Research ArticleMetabolism, Transport, and Pharmacogenomics
Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4–CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex
Haoming Zhang, Chitra Sridar, Cesar Kenaan, Hemali Amunugama, David P. Ballou and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics September 2011, 338 (3) 803-809; DOI: https://doi.org/10.1124/jpet.111.183111
Haoming Zhang
Chitra Sridar
Cesar Kenaan
Hemali Amunugama
David P. Ballou
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Research ArticleMetabolism, Transport, and Pharmacogenomics
Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4–CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex
Haoming Zhang, Chitra Sridar, Cesar Kenaan, Hemali Amunugama, David P. Ballou and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics September 1, 2011, 338 (3) 803-809; DOI: https://doi.org/10.1124/jpet.111.183111
Research ArticleMetabolism, Transport, and Pharmacogenomics
Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4–CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex
Haoming Zhang, Chitra Sridar, Cesar Kenaan, Hemali Amunugama, David P. Ballou and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics September 1, 2011, 338 (3) 803-809; DOI: https://doi.org/10.1124/jpet.111.183111
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