Research ArticleNEUROPHARMACOLOGY
First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates
Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi, Ming-Chih Crouthamel, Viswanath Devanarayan, Joan Ellis, Amy Espeseth, Adam T. Gates, Samuel L. Graham, Allison R. Gregro, Daria Hazuda, Jerome H. Hochman, Katharine Holloway, Lixia Jin, Jason Kahana, Ming-tain Lai, Janet Lineberger, Georgia McGaughey, Keith P. Moore, Philippe Nantermet, Beth Pietrak, Eric A. Price, Hemaka Rajapakse, Shaun Stauffer, Melissa A. Steinbeiser, Guy Seabrook, Harold G. Selnick, Xiao-Ping Shi, Matthew G. Stanton, John Swestock, Katherine Tugusheva, Keala X. Tyler, Joseph P. Vacca, Jacky Wong, Guoxin Wu, Min Xu, Jacquelynn J. Cook and Adam J. Simon
Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 131-140; DOI: https://doi.org/10.1124/jpet.108.143628
Sethu Sankaranarayanan
Marie A. Holahan
Dennis Colussi
Ming-Chih Crouthamel
Viswanath Devanarayan
Joan Ellis
Amy Espeseth
Adam T. Gates
Samuel L. Graham
Allison R. Gregro
Daria Hazuda
Jerome H. Hochman
Katharine Holloway
Lixia Jin
Jason Kahana
Ming-tain Lai
Janet Lineberger
Georgia McGaughey
Keith P. Moore
Philippe Nantermet
Beth Pietrak
Eric A. Price
Hemaka Rajapakse
Shaun Stauffer
Melissa A. Steinbeiser
Guy Seabrook
Harold G. Selnick
Xiao-Ping Shi
Matthew G. Stanton
John Swestock
Katherine Tugusheva
Keala X. Tyler
Joseph P. Vacca
Jacky Wong
Guoxin Wu
Min Xu
Jacquelynn J. Cook
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In this issue
Research ArticleNEUROPHARMACOLOGY
First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates
Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi, Ming-Chih Crouthamel, Viswanath Devanarayan, Joan Ellis, Amy Espeseth, Adam T. Gates, Samuel L. Graham, Allison R. Gregro, Daria Hazuda, Jerome H. Hochman, Katharine Holloway, Lixia Jin, Jason Kahana, Ming-tain Lai, Janet Lineberger, Georgia McGaughey, Keith P. Moore, Philippe Nantermet, Beth Pietrak, Eric A. Price, Hemaka Rajapakse, Shaun Stauffer, Melissa A. Steinbeiser, Guy Seabrook, Harold G. Selnick, Xiao-Ping Shi, Matthew G. Stanton, John Swestock, Katherine Tugusheva, Keala X. Tyler, Joseph P. Vacca, Jacky Wong, Guoxin Wu, Min Xu, Jacquelynn J. Cook and Adam J. Simon
Journal of Pharmacology and Experimental Therapeutics January 1, 2009, 328 (1) 131-140; DOI: https://doi.org/10.1124/jpet.108.143628
Research ArticleNEUROPHARMACOLOGY
First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates
Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi, Ming-Chih Crouthamel, Viswanath Devanarayan, Joan Ellis, Amy Espeseth, Adam T. Gates, Samuel L. Graham, Allison R. Gregro, Daria Hazuda, Jerome H. Hochman, Katharine Holloway, Lixia Jin, Jason Kahana, Ming-tain Lai, Janet Lineberger, Georgia McGaughey, Keith P. Moore, Philippe Nantermet, Beth Pietrak, Eric A. Price, Hemaka Rajapakse, Shaun Stauffer, Melissa A. Steinbeiser, Guy Seabrook, Harold G. Selnick, Xiao-Ping Shi, Matthew G. Stanton, John Swestock, Katherine Tugusheva, Keala X. Tyler, Joseph P. Vacca, Jacky Wong, Guoxin Wu, Min Xu, Jacquelynn J. Cook and Adam J. Simon
Journal of Pharmacology and Experimental Therapeutics January 1, 2009, 328 (1) 131-140; DOI: https://doi.org/10.1124/jpet.108.143628
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