Journal of Pharmacology and Experimental Therapeutics: 319 (1)

October 01, 2006; Volume 319,Issue 1

PERSPECTIVES IN PHARMACOLOGY

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An Overview of Drug Combination Analysis with Isobolograms
Ronald J. Tallarida

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 1-7; DOI: https://doi.org/10.1124/jpet.106.104117

BEHAVIORAL PHARMACOLOGY

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Metabotropic Glutamate 5 Receptor Antagonism Is Associated with Antidepressant-Like Effects in Mice
Xia Li, Anne B. Need, Melvyn Baez and Jeffrey M. Witkin

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 254-259; DOI: https://doi.org/10.1124/jpet.106.103143
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Confirmation and Fine Mapping of Ethanol Sensitivity Quantitative Trait Loci, and Candidate Gene Testing in the LXS Recombinant Inbred Mice
Beth Bennett, Phyllis Carosone-Link, Nancy R. Zahniser and Thomas E. Johnson

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 299-307; DOI: https://doi.org/10.1124/jpet.106.103572

CARDIOVASCULAR

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A Role for Nitric Oxide-Mediated Peroxynitrite Formation in a Model of Endotoxin-Induced Shock
Salvatore Cuzzocrea, Emanuela Mazzon, Rosanna Di Paola, Emanuela Esposito, Heather Macarthur, George M. Matuschak and Daniela Salvemini

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 73-81; DOI: https://doi.org/10.1124/jpet.106.108100
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The Prototypical Inhibitor of Cholesterol Esterification, Sah 58-035 [3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenylethyl]propanamide], Is an Agonist of Estrogen Receptors
Philippe de Medina, Nadia Boubekeur, Patrick Balaguer, Gilles Favre, Sandrine Silvente-Poirot and Marc Poirot

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 139-149; DOI: https://doi.org/10.1124/jpet.106.104349
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Regional Hemodynamic Effects of Neutral Endopeptidase Inhibition and Angiotensin (AT₁) Receptor Antagonism Alone or in Combination in Conscious Spontaneously Hypertensive Rats
S. M. Gardiner, J. E. March, P. A. Kemp, S. A. Ballard and T. Bennett

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 340-348; DOI: https://doi.org/10.1124/jpet.106.106781
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Simvastatin Improves Diabetes-Induced Coronary Endothelial Dysfunction
Huda E. Tawfik, Azza B. El-Remessy, Suraporn Matragoon, Guochuan Ma, Ruth B. Caldwell and R. William Caldwell

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 386-395; DOI: https://doi.org/10.1124/jpet.106.106823
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Corpus Cavernosum from Men with Vasculogenic Impotence Is Partially Resistant to Adenosine Relaxation due to Endothelial A_2B Receptor Dysfunction
Miguel Faria, Teresa Magalhães-Cardoso, José-Maria Lafuente-de-Carvalho and Paulo Correia-de-Sá

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 405-413; DOI: https://doi.org/10.1124/jpet.106.107821
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Chronic Treatment with the β₂-Adrenoceptor Agonist Prodrug BRL-47672 Impairs Rat Skeletal Muscle Function by Inducing a Comprehensive Shift to a Faster Muscle Phenotype
David J. Baker, D. Constantin-Teodosiu, Simon W. Jones, James A. Timmons and Paul L. Greenhaff

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 439-446; DOI: https://doi.org/10.1124/jpet.106.107045

CELLULAR AND MOLECULAR

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Differential Effects of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxyl]-5-pyridyl]carbamoyl]-6-trifluoromethylindone (SB 243213) on 5-Hydroxytryptamine_2C Receptor-Mediated Responses
Kelly A. Berg, Sylvia Navailles, Teresa A. Sanchez, Yamille M. Silva, Martyn D. Wood, Umberto Spampinato and William P. Clarke

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 260-268; DOI: https://doi.org/10.1124/jpet.106.104448
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Discovery of Pyrrolo[2,3-b]pyrazines Derivatives as Submicromolar Affinity Activators of Wild Type, G551D, and F508del Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels
Sabrina Noel, Christelle Faveau, Caroline Norez, Christian Rogier, Yvette Mettey and Frédéric Becq

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 349-359; DOI: https://doi.org/10.1124/jpet.106.104521
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Enzyme-Mediated Protein Haptenation of Dapsone and Sulfamethoxazole in Human Keratinocytes: I. Expression and Role of Cytochromes P450
Piyush M. Vyas, Sanjoy Roychowdhury, Farah D. Khan, Thomas E. Prisinzano, Jatinder Lamba, Erin G. Schuetz, Joyce Blaisdell, Joyce A. Goldstein, Kimber L. Munson, Ronald N. Hines and Craig K. Svensson

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 488-496; DOI: https://doi.org/10.1124/jpet.106.105858
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Enzyme-Mediated Protein Haptenation of Dapsone and Sulfamethoxazole in Human Keratinocytes: II. Expression and Role of Flavin-Containing Monooxygenases and Peroxidases
Piyush M. Vyas, Sanjoy Roychowdhury, Sevasti B. Koukouritaki, Ronald N. Hines, Sharon K. Krueger, David E. Williams, William M. Nauseef and Craig K. Svensson

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 497-505; DOI: https://doi.org/10.1124/jpet.106.105874

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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Inhibition of the Enzymatic Activity of Heme Oxygenases by Azole-Based Antifungal Drugs
Robert T. Kinobe, Ryan A. Dercho, Jason Z. Vlahakis, James F. Brien, Walter A. Szarek and Kanji Nakatsu

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 277-284; DOI: https://doi.org/10.1124/jpet.106.102699

ENDOCRINE AND DIABETES

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Inhibition of Protein Kinase Cβ Protects against Diabetes-Induced Impairment in Arachidonic Acid Dilation of Small Coronary Arteries
Wei Zhou, Xiao-Li Wang, Kathryn G. Lamping and Hon-Chi Lee

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 199-207; DOI: https://doi.org/10.1124/jpet.106.106666

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Intracellular Delivery of the p38 Mitogen-Activated Protein Kinase Inhibitor SB202190 [4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in Renal Tubular Cells: A Novel Strategy to Treat Renal Fibrosis
Jai Prakash, Maria Sandovici, Vinay Saluja, Marie Lacombe, Roel Q. J. Schaapveld, Martin H. de Borst, Harry van Goor, Robert H. Henning, Johannes H. Proost, Frits Moolenaar, György Këri, Dirk K. F. Meijer, Klaas Poelstra and Robbert J. Kok

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 8-19; DOI: https://doi.org/10.1124/jpet.106.106054
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Y₄ Receptors Mediate the Inhibitory Responses of Pancreatic Polypeptide in Human and Mouse Colon Mucosa
Iain R. Tough, Nicholas D. Holliday and Helen M. Cox

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 20-30; DOI: https://doi.org/10.1124/jpet.106.106500
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Role of Renal Nerves and Salt Intake on Erythropoietin Secretion in Rats following Carbon Monoxide Exposure
Cathérine Gebhard, Fotios Petroktistis, Hua Zhang, Daniel Kammerer, Christoph Köhle, Karin Klingel, Margitta Albinus, Christoph H. Gleiter, Hartmut Osswald and Almut Grenz

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 111-116; DOI: https://doi.org/10.1124/jpet.106.105973
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Acid-Induced Release of Platelet-Activating Factor by Human Esophageal Mucosa Induces Inflammatory Mediators in Circular Smooth Muscle
Ling Cheng, Weibiao Cao, Jose Behar, Claudio Fiocchi, Piero Biancani and Karen M. Harnett

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 117-126; DOI: https://doi.org/10.1124/jpet.106.106104
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Therapeutic Potential of (-)-Epigallocatechin 3-O-Gallate on Renal Damage in Diabetic Nephropathy Model Rats
Noriko Yamabe, Takako Yokozawa, Takeshi Oya and Mujo Kim

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 228-236; DOI: https://doi.org/10.1124/jpet.106.107029
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5-Amino-2-hydroxybenzoic Acid 4-(5-Thioxo-5H-[1,2]dithiol-3yl)-phenyl Ester (ATB-429), a Hydrogen Sulfide-Releasing Derivative of Mesalamine, Exerts Antinociceptive Effects in a Model of Postinflammatory Hypersensitivity
Eleonora Distrutti, Luca Sediari, Andrea Mencarelli, Barbara Renga, Stefano Orlandi, Giuseppe Russo, Giuseppe Caliendo, Vincenzo Santagada, Giuseppe Cirino, John L. Wallace and Stefano Fiorucci

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 447-458; DOI: https://doi.org/10.1124/jpet.106.106435
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Prostaglandin/Cyclooxygenase Pathway in Ghrelin-Induced Gastroprotection against Ischemia-Reperfusion Injury
Tomasz Brzozowski, Peter C. Konturek, Zbigniew Sliwowski, Robert Pajdo, Danuta Drozdowicz, Slawomir Kwiecien, Grzegorz Burnat, Stanislaw J. Konturek and Wieslaw W. Pawlik

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 477-487; DOI: https://doi.org/10.1124/jpet.106.105932

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA

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Interleukin-10 Protects Lipopolysaccharide-Induced Neurotoxicity in Primary Midbrain Cultures by Inhibiting the Function of NADPH Oxidase
Li Qian, Michelle L. Block, Sung-Jen Wei, Chiou-feng Lin, Jeffrey Reece, Hao Pang, Belinda Wilson, Jau-Shyong Hong and Patrick M. Flood

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 44-52; DOI: https://doi.org/10.1124/jpet.106.106351
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Peripheral Phosphodiesterase 4 Inhibition Produced by 4-[2-(3,4-Bis-difluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) Prevents Experimental Autoimmune Encephalomyelitis
C. S. Moore, N. Earl, R. Frenette, A. Styhler, J. A. Mancini, D. W. Nicholson, A. L. O. Hebb, T. Owens and G. S. Robertson

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 63-72; DOI: https://doi.org/10.1124/jpet.106.106096
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Glucocerebroside Ameliorates the Metabolic Syndrome in OB/OB Mice
Maya Margalit, Zvi Shalev, Orit Pappo, Miriam Sklair-Levy, Ruslana Alper, Moshe Gomori, Dean Engelhardt, Elazar Rabbani and Yaron Ilan

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 105-110; DOI: https://doi.org/10.1124/jpet.106.104950
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Poly(ADP-Ribose) Glycohydrolase Activity Mediates Post-Traumatic Inflammatory Reaction after Experimental Spinal Cord Trauma
Salvatore Cuzzocrea, Tiziana Genovese, Emanuela Mazzon, Concetta Crisafulli, Wookee Min, Rosanna Di Paola, Carmelo Muià, Jia-He Li, Emanuela Esposito, Placido Bramanti, Weizheng Xu, Edmond Massuda, Jie Zhang and Zhao-Qi Wang

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 127-138; DOI: https://doi.org/10.1124/jpet.106.108076
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Cannabinoid Treatment Suppresses the T-Helper Cell-Polarizing Function of Mouse Dendritic Cells Stimulated with Legionella pneumophila Infection
Tangying Lu, Cathy Newton, Izabella Perkins, Herman Friedman and Thomas W. Klein

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 269-276; DOI: https://doi.org/10.1124/jpet.106.108381
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Basiliolides, a Class of Tetracyclic C19 Dilactones from Thapsia garganica, Release Ca²⁺ from the Endoplasmic Reticulum and Regulate the Activity of the Transcription Factors Nuclear Factor of Activated T Cells, Nuclear Factor-κB, and Activator Protein 1 in T Lymphocytes
Carmen Navarrete, Rocío Sancho, Francisco J. Caballero, Federica Pollastro, Bernd L. Fiebich, Olov Sterner, Giovanni Appendino and Eduardo Muñoz

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 422-430; DOI: https://doi.org/10.1124/jpet.106.108209
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Phosphodiesterase Type 4 Inhibitors Cause Proinflammatory Effects in Vivo
Kerryn McCluskie, Uwe Klein, Chris Linnevers, Yu-hua Ji, Alfred Yang, Craig Husfeld and G. Roger Thomas

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 468-476; DOI: https://doi.org/10.1124/jpet.106.105080

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS

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Expression and Transport Activity of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Dually Perfused Rat Placenta and HRP-1 Cell Line
Frantisek Staud, Zuzana Vackova, Katerina Pospechova, Petr Pavek, Martina Ceckova, Antonin Libra, Lenka Cygalova, Petr Nachtigal and Zdenek Fendrich

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 53-62; DOI: https://doi.org/10.1124/jpet.106.105023
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A Mechanistic Study on Reduced Toxicity of Irinotecan by Coadministered Thalidomide, a Tumor Necrosis Factor-α Inhibitor
Xiao-Xia Yang, Ze-Ping Hu, An-Long Xu, Wei Duan, Yi-Zhun Zhu, Min Huang, Fwu-Shan Sheu, Qiang Zhang, Jin-Song Bian, Eli Chan, Xiaotian Li, Jian-Cheng Wang and Shu-Feng Zhou

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 82-104; DOI: https://doi.org/10.1124/jpet.106.103606
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Human Organic Anion Transporter 3 Gene Is Regulated Constitutively and Inducibly via a cAMP-Response Element
Ken Ogasawara, Tomohiro Terada, Jun-ichi Asaka, Toshiya Katsura and Ken-ichi Inui

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 317-322; DOI: https://doi.org/10.1124/jpet.106.108233
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The Role of Retinoid X Receptor α in Regulating Alcohol Metabolism
Maxwell Afari Gyamfi, Michael George Kocsis, Lin He, Guoli Dai, Alphonse John Mendy and Yu-Jui Yvonne Wan

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 360-368; DOI: https://doi.org/10.1124/jpet.106.108175
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Differential Involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in Biliary Excretion of 4-Methylumbelliferyl Glucuronide and Sulfate in the Rat
Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Joan E. Humphreys, Xianbin Tian, Ken-ichi Nezasa and Kim L. R. Brouwer

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 459-467; DOI: https://doi.org/10.1124/jpet.106.101840

NEUROPHARMACOLOGY

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Heterogeneous Dopamine Neurochemistry in the Striatum: The Fountain-Drain Matrix
Manuel Rodriguez, Ingrid Morales, Isabel Gomez, Sergio Gonzalez, Tomas Gonzalez-Hernandez and Jose Luis Gonzalez-Mora

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 31-43; DOI: https://doi.org/10.1124/jpet.106.104687
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Role for Neuronal Nitric-Oxide Synthase in Cannabinoid-Induced Neurogenesis
Sun Hee Kim, Seok Joon Won, Xiao Ou Mao, Catherine Ledent, Kunlin Jin and David A. Greenberg

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 150-154; DOI: https://doi.org/10.1124/jpet.106.107698
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Iptakalim Modulates ATP-Sensitive K⁺ Channels in Dopamine Neurons from Rat Substantia Nigra Pars Compacta
Jie Wu, Jun Hu, Yu-Ping Chen, Teruko Takeo, Sechiko Suga, Jamie DeChon, Qiang Liu, Ke-Chun Yang, Paul A. St. John, Gang Hu, Hai Wang and Makoto Wakui

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 155-164; DOI: https://doi.org/10.1124/jpet.106.106286
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Involvement of Multitargets in Paeoniflorin-Induced Preconditioning
Dong-Mei Chen, Liang Xiao, Xin Cai, Rong Zeng and Xing-Zu Zhu

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 165-180; DOI: https://doi.org/10.1124/jpet.106.104380
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Gabapentin-Lactam Induces Dendritic Filopodia and Motility in Cultured Hippocampal Neurons
Frank Henle, Jost Leemhuis, Catharina Fischer, Hans H. Bock, Kerstin Lindemeyer, Thomas J. Feuerstein and Dieter K. Meyer

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 181-191; DOI: https://doi.org/10.1124/jpet.106.106146
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A Polyclonal Antibody to the Prepore Loop of Transient Receptor Potential Vanilloid Type 1 Blocks Channel Activation
Lana Klionsky, Rami Tamir, Bob Holzinger, Xiaojuan Bi, Jane Talvenheimo, Helen Kim, Frank Martin, Jean-Claude Louis, James J. S. Treanor and Narender R. Gavva

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 192-198; DOI: https://doi.org/10.1124/jpet.106.108092
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An Isoflurane- and Alcohol-Insensitive Mutant GABA_A Receptor α₁ Subunit with Near-Normal Apparent Affinity for GABA: Characterization in Heterologous Systems and Production of Knockin Mice
C. M. Borghese, D. F. Werner, N. Topf, N. V. Baron, L. A. Henderson, S. L. Boehm, Y. A. Blednov, A. Saad, S. Dai, R. A. Pearce, R. A. Harris, G. E. Homanics and N. L. Harrison

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 208-218; DOI: https://doi.org/10.1124/jpet.106.104406
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Knockin Mice with Ethanol-Insensitive α1-Containing γ-Aminobutyric Acid Type A Receptors Display Selective Alterations in Behavioral Responses to Ethanol
David F. Werner, Yuri A. Blednov, Olusegun J. Ariwodola, Yuval Silberman, Exazevia Logan, Raymond B. Berry, Cecilia M. Borghese, Douglas B. Matthews, Jeffrey L. Weiner, Neil L. Harrison, R. Adron Harris and Gregg E. Homanics

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 219-227; DOI: https://doi.org/10.1124/jpet.106.106161
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Interaction of Amphetamines and Related Compounds at the Vesicular Monoamine Transporter
John S. Partilla, Allison G. Dempsey, Ameet S. Nagpal, Bruce E. Blough, Michael H. Baumann and Richard B. Rothman

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 237-246; DOI: https://doi.org/10.1124/jpet.106.103622
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Separation of Binding Affinity and Intrinsic Activity of the Potent μ-Opioid 14-Methoxymetopon
Loriann Mahurter, Carrie Garceau, Jacqueline Marino, Helmut Schmidhammer, Géza Tóth and Gavril W. Pasternak

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 247-253; DOI: https://doi.org/10.1124/jpet.106.105395
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Partial Recovery of Striatal Nicotinic Receptors in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Lesioned Monkeys with Chronic Oral Nicotine
Tanuja Bordia, Neeraja Parameswaran, Hong Fan, J. William Langston, J. Michael McIntosh and Maryka Quik

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 285-292; DOI: https://doi.org/10.1124/jpet.106.106997
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Pharmacological Characterization of cGMP Regulation by the Biarylpropylsulfonamide Class of Positive, Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors
John W. Ryder, Julie F. Falcone, Jason R. Manro, Kjell A. Svensson and Kalpana M. Merchant

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 293-298; DOI: https://doi.org/10.1124/jpet.106.105734
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Utilization of Combined Chemical Modifications to Enhance the Blood-Brain Barrier Permeability and Pharmacological Activity of Endomorphin-1
Hong-Mei Liu, Xue-Feng Liu, Jin-Long Yao, Chang-Lin Wang, Ye Yu and Rui Wang

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 308-316; DOI: https://doi.org/10.1124/jpet.106.106484
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Interaction of Riluzole with the Closed Inactivated State of Kv4.3 Channels
Hye Sook Ahn, Sung Eun Kim, Hyun-Jong Jang, Myung-Jun Kim, Duck-Joo Rhie, Shin-Hee Yoon, Yang-Hyeok Jo, Myung-Suk Kim, Ki-Wug Sung and Sang June Hahn

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 323-331; DOI: https://doi.org/10.1124/jpet.106.106724
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NAP Enhances Neurodevelopment of Newborn Apolipoprotein E-Deficient Mice Subjected to Hypoxia
Michael Rotstein, Haim Bassan, Naam Kariv, Zipora Speiser, Shaul Harel and Illana Gozes

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 332-339; DOI: https://doi.org/10.1124/jpet.106.106898
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The Magnitude of α7 Nicotinic Receptor Currents in Rat Hippocampal Neurons Is Dependent upon GABAergic Activity and Depolarization
Hélio R. Santos, Helizane S. Ribeiro, Pedro Setti-Perdigão, Edson X. Albuquerque and Newton G. Castro

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 376-385; DOI: https://doi.org/10.1124/jpet.106.106385
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Antiallodynic and Antihyperalgesic Effects of Selective Competitive GLU_K5 (GluR5) Ionotropic Glutamate Receptor Antagonists in the Capsaicin and Carrageenan Models in Rats
Carrie K. Jones, Andrew Alt, Ann Marie Ogden, David Bleakman, Rosa M. A. Simmons, Smriti Iyengar, Esteban Dominguez, Paul L. Ornstein and Harlan E. Shannon

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 396-404; DOI: https://doi.org/10.1124/jpet.106.105601
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Multiple High Doses of Methamphetamine Increase the Number of Preproneuropeptide Y mRNA-Expressing Neurons in the Striatum of Rat via a Dopamine D1 Receptor-Dependent Mechanism
Kristen A. Horner, Scot C. Westwood, Glen R. Hanson and Kristen A. Keefe

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 414-421; DOI: https://doi.org/10.1124/jpet.106.106856
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Effects of Ethanol on Tonic GABA Currents in Cerebellar Granule Cells and Mammalian Cells Recombinantly Expressing GABA_A Receptors
Megumi Yamashita, William Marszalec, Jay Z. Yeh and Toshio Narahashi

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 431-438; DOI: https://doi.org/10.1124/jpet.106.106260

TOXICOLOGY

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Identification and Characterization of Functional Rat Arylamine N-Acetyltransferase 3: Comparisons with Rat Arylamine N-Acetyltransferases 1 and 2
Jason M. Walraven, Mark A. Doll and David W. Hein

Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 369-375; DOI: https://doi.org/10.1124/jpet.106.108399

Erratum

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Correction to “Mitochondrial Arginase II Modulates Nitric-Oxide Synthesis through Nonfreely Exchangeable l-Arginine Pools in Human Endothelial Cells”
Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 506;

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND DIABETES

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS

NEUROPHARMACOLOGY

TOXICOLOGY

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