Table of Contents

May 2003; 305 (2)

PERSPECTIVES IN PHARMACOLOGY

    • Lawrence H. Lash,
    • Ronald N. Hines,
    • Frank J. Gonzalez,
    • Timothy R. Zacharewski,
    • and Mark A. Rothstein

    Genetics and Susceptibility to Toxic Chemicals: Do You (or Should You) Know Your Genetic Profile?

    J Pharmacol Exp Ther May 1, 2003 305:403-409; published ahead of print January 24, 2003, doi:10.1124/jpet.102.039925
    • Keith A. Gary,
    • Kevin A. Sevarino,
    • George G. Yarbrough,
    • Arthur J. Prange, Jr.,
    • and Andrew Winokur

    The Thyrotropin-Releasing Hormone (TRH) Hypothesis of Homeostatic Regulation: Implications for TRH-Based Therapeutics

    J Pharmacol Exp Ther May 1, 2003 305:410-416; published ahead of print February 20, 2003, doi:10.1124/jpet.102.044040

INFLAMMATION AND IMMUNOPHARMACOLOGY

    • Bryan L. Copple,
    • Frederic Moulin,
    • Umesh M. Hanumegowda,
    • Patricia E. Ganey,
    • and Robert A. Roth

    Thrombin and Protease-Activated Receptor-1 Agonists Promote Lipopolysaccharide-Induced Hepatocellular Injury in Perfused Livers

    J Pharmacol Exp Ther May 1, 2003 305:417-425; published ahead of print January 24, 2003, doi:10.1124/jpet.102.046391

CARDIOVASCULAR

    • Irina Korichneva,
    • John Waka,
    • and Ulrich Hammerling

    Regulation of the Cardiac Mitochondrial Membrane Potential by Retinoids

    J Pharmacol Exp Ther May 1, 2003 305:426-433; published ahead of print January 24, 2003, doi:10.1124/jpet.103.048900
    • Liping Gao,
    • Chongxue Zhu,
    • and Edwin K. Jackson

    α2-Adrenoceptors Potentiate Angiotensin II- and Vasopressin-Induced Renal Vasoconstriction in Spontaneously Hypertensive Rats

    J Pharmacol Exp Ther May 1, 2003 305:581-586; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047647
    • Toshio Obata,
    • Hidetoshi Yonemochi,
    • and Makoto Arita

    Norepinephrine Evoked by Potassium Depolarization Increases Interstitial Adenosine Concentration via Activation of ecto-5′-Nucleotidase in Rat Hearts

    J Pharmacol Exp Ther May 1, 2003 305:719-724; published ahead of print February 11, 2003, doi:10.1124/jpet.102.039917
    • Robert Létienne,
    • Yvan Verscheure,
    • Michel Perez,
    • Bruno Le Grand,
    • Francis C. Colpaert,
    • and Gareth W. John

    Donitriptan Selectively Decreases Jugular Venous Oxygen Saturation in the Anesthetized Pig: Further Insights into Its Mechanism of Action Relevant to Headache Relief

    J Pharmacol Exp Ther May 1, 2003 305:749-754; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047225
    • M. Rocchetti,
    • A. Besana,
    • G. Mostacciuolo,
    • P. Ferrari,
    • R. Micheletti,
    • and A. Zaza

    Diverse Toxicity Associated with Cardiac Na+/K+ Pump Inhibition: Evaluation of Electrophysiological Mechanisms

    J Pharmacol Exp Ther May 1, 2003 305:765-771; published ahead of print February 20, 2003, doi:10.1124/jpet.102.047696
    • D. F. Woodward,
    • A. H.-P. Krauss,
    • J. Chen,
    • Y. Liang,
    • C. Li,
    • C. E. Protzman,
    • A. Bogardus,
    • R. Chen,
    • K. M. Kedzie,
    • H. A. Krauss,
    • D. W. Gil,
    • A. Kharlamb,
    • L. A. Wheeler,
    • D. Babusis,
    • D. Welty,
    • D. D.-S. Tang-Liu,
    • M. Cherukury,
    • S. W. Andrews,
    • R. M. Burk,
    • and M. E. Garst

    Pharmacological Characterization of a Novel Antiglaucoma Agent, Bimatoprost (AGN 192024)

    J Pharmacol Exp Ther May 1, 2003 305:772-785; published ahead of print January 24, 2003, doi:10.1124/jpet.102.047837

NEUROPHARMACOLOGY

    • Michelle L. Gilmor,
    • Kelly H. Skelton,
    • Charles B. Nemeroff,
    • and Michael J. Owens

    The Effects of Chronic Treatment with the Mood Stabilizers Valproic Acid and Lithium on Corticotropin-Releasing Factor Neuronal Systems

    J Pharmacol Exp Ther May 1, 2003 305:434-439; published ahead of print January 24, 2003, doi:10.1124/jpet.102.045419
    • Michel Bottlaender,
    • Frédéric Dollé,
    • Ilonka Guenther,
    • Dimitri Roumenov,
    • Chantal Fuseau,
    • Yann Bramoulle,
    • Olivier Curet,
    • Jamir Jegham,
    • Jean-Louis Pinquier,
    • Pascal George,
    • and Heric Valette

    Mapping the Cerebral Monoamine Oxidase Type A: Positron Emission Tomography Characterization of the Reversible Selective Inhibitor [11C]Befloxatone

    J Pharmacol Exp Ther May 1, 2003 305:467-473; published ahead of print February 11, 2003, doi:10.1124/jpet.102.046953
    • Makoto Inoue,
    • Toshiko Kawashima,
    • Hiroshi Takeshima,
    • Girolamo Calo,
    • Atsuko Inoue,
    • Yoshihiro Nakata,
    • and Hiroshi Ueda

    In Vivo Pain-Inhibitory Role of Nociceptin/Orphanin FQ in Spinal Cord

    J Pharmacol Exp Ther May 1, 2003 305:495-501; published ahead of print January 24, 2003, doi:10.1124/jpet.102.046326
    • Xue Qing Wang,
    • Ai Ying Xiao,
    • Aizhen Yang,
    • Lori LaRose,
    • Ling Wei,
    • and Shan Ping Yu

    Block of Na+,K+-ATPase and Induction of Hybrid Death by 4-Aminopyridine in Cultured Cortical Neurons

    J Pharmacol Exp Ther May 1, 2003 305:502-506; published ahead of print January 21, 2003, doi:10.1124/jpet.102.045013
    • Regina P. Markus,
    • Jussara M. Santos,
    • Wagner Zago,
    • and Lı́via A. C. Renó

    Melatonin Nocturnal Surge Modulates Nicotinic Receptors and Nicotine-Induced [3H]Glutamate Release in Rat Cerebellum Slices

    J Pharmacol Exp Ther May 1, 2003 305:525-530; published ahead of print January 24, 2003, doi:10.1124/jpet.102.045625
    • Yu Zhao,
    • Han-Ting Zhang,
    • and James M. O'Donnell

    Inhibitor Binding to Type 4 Phosphodiesterase (PDE4) Assessed Using [3H]Piclamilast and [3H]Rolipram

    J Pharmacol Exp Ther May 1, 2003 305:565-572; published ahead of print January 24, 2003, doi:10.1124/jpet.102.047407
    • J. E. Kralic,
    • M. Wheeler,
    • K. Renzi,
    • C. Ferguson,
    • T. K. O'Buckley,
    • A. C. Grobin,
    • A. L. Morrow,
    • and G. E. Homanics

    Deletion of GABAA Receptor α1 Subunit-containing Receptors Alters Responses to Ethanol and Other Anesthetics

    J Pharmacol Exp Ther May 1, 2003 305:600-607; published ahead of print February 11, 2003, doi:10.1124/jpet.102.048124
    • Shitij Kapur,
    • Susan C. VanderSpek,
    • Barbara A. Brownlee,
    • and José N. Nobrega

    Antipsychotic Dosing in Preclinical Models Is Often Unrepresentative of the Clinical Condition: A Suggested Solution Based on in Vivo Occupancy

    J Pharmacol Exp Ther May 1, 2003 305:625-631; published ahead of print February 20, 2003, doi:10.1124/jpet.102.046987
    • Michael T. Flink and
    • William D. Atchison

    Iberiotoxin-Induced Block of Ca2+-Activated K+ Channels Induces Dihydropyridine Sensitivity of ACh Release from Mammalian Motor Nerve Terminals

    J Pharmacol Exp Ther May 1, 2003 305:646-652; published ahead of print January 24, 2003, doi:10.1124/jpet.102.046102
    • Natalie R. Lenard,
    • Thomas W. Gettys,
    • and Adrian J. Dunn

    Activation of β2- and β3-Adrenergic Receptors Increases Brain Tryptophan

    J Pharmacol Exp Ther May 1, 2003 305:653-659; published ahead of print January 24, 2003, doi:10.1124/jpet.102.048249
    • Wei-Xing Shi and
    • Xue-Xiang Zhang

    Dendritic Glutamate-Induced Bursting in the Prefrontal Cortex: Further Characterization and Effects of Phencyclidine

    J Pharmacol Exp Ther May 1, 2003 305:680-687; published ahead of print January 24, 2003, doi:10.1124/jpet.102.046359
    • Hazel H. Szeto,
    • Yi Soong,
    • Dunli Wu,
    • XuanXuan Qian,
    • and Guo-Min Zhao

    Endogenous Opioid Peptides Contribute to Antinociceptive Potency of Intrathecal [Dmt1]DALDA

    J Pharmacol Exp Ther May 1, 2003 305:696-702; published ahead of print January 24, 2003, doi:10.1124/jpet.102.048561
    • Sonya G. Wilson,
    • Camron D. Bryant,
    • William R. Lariviere,
    • Michael S. Olsen,
    • Belinda E. Giles,
    • Elissa J. Chesler,
    • and Jeffrey S. Mogil

    The Heritability of Antinociception II: Pharmacogenetic Mediation of Three Over-the-Counter Analgesics in Mice

    J Pharmacol Exp Ther May 1, 2003 305:755-764; published ahead of print February 20, 2003, doi:10.1124/jpet.102.047902

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

    • Carolyn B. Coyne,
    • Carla M. P. Ribeiro,
    • Richard C. Boucher,
    • and Larry G. Johnson

    Acute Mechanism of Medium Chain Fatty Acid-Induced Enhancement of Airway Epithelial Permeability

    J Pharmacol Exp Ther May 1, 2003 305:440-450; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047654
    • Zoltán Kapui,
    • Márton Varga,
    • Katalin Urban-Szabó,
    • Endre Mikus,
    • Tibor Szabó,
    • Judit Szeredi,
    • Sándor Bátori,
    • Olivier Finance,
    • and Péter Arányi

    Biochemical and Pharmacological Characterization of 2-(9-(2-Piperidinoethoxy)-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yloxymethyl)-4-(1-methylethyl)-6-methoxy-1,2-benzisothiazol-3(2H)-one-1,1-dioxide (SSR69071), a Novel, Orally Active Elastase Inhibitor

    J Pharmacol Exp Ther May 1, 2003 305:451-459; published ahead of print February 11, 2003, doi:10.1124/jpet.102.044263
    • Florian Loher,
    • Kathrin Schmall,
    • Philipp Freytag,
    • Nikola Landauer,
    • Roland Hallwachs,
    • Christian Bauer,
    • Britta Siegmund,
    • Florian Rieder,
    • Hans-Anton Lehr,
    • Marc Dauer,
    • Joachim Friedrich Kapp,
    • Stefan Endres,
    • and Andreas Eigler

    The Specific Type-4 Phosphodiesterase Inhibitor Mesopram Alleviates Experimental Colitis in Mice

    J Pharmacol Exp Ther May 1, 2003 305:549-556; published ahead of print February 11, 2003, doi:10.1124/jpet.102.039529
    • Sandeep Rathi,
    • Shiva Kazerounian,
    • Kuldip Banwait,
    • Stephanie Schulz,
    • Scott A. Waldman,
    • and Satish Rattan

    Functional and Molecular Characterization of β-Adrenoceptors in the Internal Anal Sphincter

    J Pharmacol Exp Ther May 1, 2003 305:615-624; published ahead of print February 11, 2003, doi:10.1124/jpet.102.048462
    • Inge Depoortere,
    • Theo Thijs,
    • Leen Thielemans,
    • Patrick Robberecht,
    • and Theo L. Peeters

    Interaction of the Growth Hormone-Releasing Peptides Ghrelin and Growth Hormone-Releasing Peptide-6 with the Motilin Receptor in the Rabbit Gastric Antrum

    J Pharmacol Exp Ther May 1, 2003 305:660-667; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047563
    • Benedict T. Green,
    • Andrew Calvin,
    • Scott M. O'Grady,
    • and David R. Brown

    Kinin-Induced Anion-Dependent Secretion in Porcine Ileum: Characterization and Involvement of Opioid- and Cannabinoid-Sensitive Enteric Neural Circuits

    J Pharmacol Exp Ther May 1, 2003 305:733-739; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047829

CELLULAR AND MOLECULAR

    • Janice Y. Zhou,
    • Peter T. Toth,
    • and Richard J. Miller

    Direct Interactions between the Heterotrimeric G Protein Subunit Gβ5 and the G Protein γ Subunit-Like Domain-Containing Regulator of G Protein Signaling 11: Gain of Function of Cyan Fluorescent Protein-Tagged Gγ3

    J Pharmacol Exp Ther May 1, 2003 305:460-466; published ahead of print February 11, 2003, doi:10.1124/jpet.102.048637
    • Jong-M. Kim,
    • Hae R. Bae,
    • Bong S. Park,
    • Je M. Lee,
    • Hee B. Ahn,
    • Jee H. Rho,
    • Kyung W. Yoo,
    • Woo C. Park,
    • Sae H. Rho,
    • Hee S. Yoon,
    • and Young Hyun Yoo

    Early Mitochondrial Hyperpolarization and Intracellular Alkalinization in Lactacystin-Induced Apoptosis of Retinal Pigment Epithelial Cells

    J Pharmacol Exp Ther May 1, 2003 305:474-481; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047811
    • A. Banan,
    • A. Farhadi,
    • J. Z. Fields,
    • L. J. Zhang,
    • M. Shaikh,
    • and A. Keshavarzian

    The δ-Isoform of Protein Kinase C Causes Inducible Nitric-Oxide Synthase and Nitric Oxide Up-Regulation: Key Mechanism for Oxidant-Induced Carbonylation, Nitration, and Disassembly of the Microtubule Cytoskeleton and Hyperpermeability of Barrier of Intestinal Epithelia

    J Pharmacol Exp Ther May 1, 2003 305:482-494; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047308
    • Sylwia Ammoun,
    • Tomas Holmqvist,
    • Ramin Shariatmadari,
    • Hendrica B. Oonk,
    • Michel Detheux,
    • Marc Parmentier,
    • Karl E. O. Åkerman,
    • and Jyrki P. Kukkonen

    Distinct Recognition of OX1 and OX2Receptors by Orexin Peptides

    J Pharmacol Exp Ther May 1, 2003 305:507-514; published ahead of print January 24, 2003, doi:10.1124/jpet.102.048025
    • Jian-Guo Li,
    • Fengqin Zhang,
    • Xi-Lu Jin,
    • and Lee-Yuan Liu-Chen

    Differential Regulation of the Human κ Opioid Receptor by Agonists: Etorphine and Levorphanol Reduced Dynorphin A- and U50,488H-Induced Internalization and Phosphorylation

    J Pharmacol Exp Ther May 1, 2003 305:531-540; published ahead of print January 24, 2003, doi:10.1124/jpet.102.045559
    • Xi-Lin Chen,
    • Qiang Zhang,
    • Ruozhi Zhao,
    • Xiaoyu Ding,
    • Pradyumna E. Tummala,
    • and Russell M. Medford

    Rac1 and Superoxide Are Required for the Expression of Cell Adhesion Molecules Induced by Tumor Necrosis Factor-α in Endothelial Cells

    J Pharmacol Exp Ther May 1, 2003 305:573-580; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047894
    • G. Hawcroft,
    • S. H. Gardner,
    • and M. A. Hull

    Activation of Peroxisome Proliferator-Activated Receptor γ Does Not Explain the Antiproliferative Activity of the Nonsteroidal Anti-Inflammatory Drug Indomethacin on Human Colorectal Cancer Cells

    J Pharmacol Exp Ther May 1, 2003 305:632-637; published ahead of print February 11, 2003, doi:10.1124/jpet.103.048769
    • Kyoungho Suk,
    • Heasuk Lee,
    • Sang Soo Kang,
    • Gyeong Jae Cho,
    • and Wan Sung Choi

    Flavonoid Baicalein Attenuates Activation-Induced Cell Death of Brain Microglia

    J Pharmacol Exp Ther May 1, 2003 305:638-645; published ahead of print January 21, 2003, doi:10.1124/jpet.102.047373
    • Keith Williams,
    • Michael Dattilo,
    • Thomas N. Sabado,
    • Keiko Kashiwagi,
    • and Kazuei Igarashi.

    Pharmacology of δ2 Glutamate Receptors: Effects of Pentamidine and Protons

    J Pharmacol Exp Ther May 1, 2003 305:740-748; published ahead of print February 11, 2003, doi:10.1124/jpet.102.045799
    • Francesca Novi,
    • Marco Scarselli,
    • Giovanni U. Corsini,
    • and Roberto Maggio

    An Unusual Form of the Association Binding Kinetics ofN-[3H]Methylscopolamine to the Split Muscarinic M2trunk/M2tail Receptor

    J Pharmacol Exp Ther May 1, 2003 305:786-795; published ahead of print January 24, 2003, doi:10.1124/jpet.102.045393

ENDOCRINE AND REPRODUCTIVE

    • M. A. Serrano,
    • R. I. R. Macias,
    • M. Vallejo,
    • O. Briz,
    • A. Bravo,
    • M. J. Pascual,
    • M. V. St-Pierre,
    • B. Stieger,
    • P. J. Meier,
    • and J. J. G. Marin

    Effect of Ursodeoxycholic Acid on the Impairment Induced by Maternal Cholestasis in the Rat Placenta-Maternal Liver Tandem Excretory Pathway

    J Pharmacol Exp Ther May 1, 2003 305:515-524; published ahead of print January 24, 2003, doi:10.1124/jpet.102.047977
    • Jo Ann Janovick,
    • Mark Goulet,
    • Eugene Bush,
    • Jonathan Greer,
    • David G. Wettlaufer,
    • and P. Michael Conn

    Structure-Activity Relations of Successful Pharmacologic Chaperones for Rescue of Naturally Occurring and Manufactured Mutants of the Gonadotropin-Releasing Hormone Receptor

    J Pharmacol Exp Ther May 1, 2003 305:608-614; published ahead of print February 11, 2003, doi:10.1124/jpet.102.048454
    • Kenna L. Anderes,
    • David R. Luthin,
    • Rosemary Castillo,
    • Eugenia A. Kraynov,
    • Mary Castro,
    • Karen Nared-Hood,
    • Margaret L. Gregory,
    • Ved P. Pathak,
    • Lance C. Christie,
    • Genevieve Paderes,
    • Haresh Vazir,
    • Qiang Ye,
    • Mark B. Anderson,
    • and John M. May

    Biological Characterization of a Novel, Orally Active Small Molecule Gonadotropin-Releasing Hormone (GnRH) Antagonist Using Castrated and Intact Rats

    J Pharmacol Exp Ther May 1, 2003 305:688-695; published ahead of print January 24, 2003, doi:10.1124/jpet.102.046656

BEHAVIORAL PHARMACOLOGY

    • M. Gulinello and
    • S. S. Smith

    Anxiogenic Effects of Neurosteroid Exposure: Sex Differences and Altered GABAA Receptor Pharmacology in Adult Rats

    J Pharmacol Exp Ther May 1, 2003 305:541-548; published ahead of print February 11, 2003, doi:10.1124/jpet.102.045120
    • Matthew C. Lee,
    • Forrest L. Smith,
    • David L. Stevens,
    • and Sandra P. Welch

    The Role of Several Kinases in Mice Tolerant to Δ9-Tetrahydrocannabinol

    J Pharmacol Exp Ther May 1, 2003 305:593-599; published ahead of print February 11, 2003, doi:10.1124/jpet.102.044446
    • Lawrence P. Carter,
    • Lauren R. Flores,
    • Huifang Wu,
    • Weibin Chen,
    • Andrew W. Unzeitig,
    • Andy Coop,
    • and Charles P. France

    The Role of GABAB Receptors in the Discriminative Stimulus Effects of γ-Hydroxybutyrate in Rats: Time Course and Antagonism Studies

    J Pharmacol Exp Ther May 1, 2003 305:668-674; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047860
    • Huifang Wu,
    • Nick Zink,
    • Lawrence P. Carter,
    • Ashok K. Mehta,
    • R. Jason Hernandez,
    • Maharaj K. Ticku,
    • Richard Lamb,
    • Charles P. France,
    • and Andrew Coop

    A Tertiary Alcohol Analog of γ-Hydroxybutyric Acid as a Specific γ-Hydroxybutyric Acid Receptor Ligand

    J Pharmacol Exp Ther May 1, 2003 305:675-679; published ahead of print January 21, 2003, doi:10.1124/jpet.102.046797

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

    • Undi Hoffler,
    • Hisham A. El-Masri,
    • and Burhan I. Ghanayem

    Cytochrome P450 2E1 (CYP2E1) Is the Principal Enzyme Responsible for Urethane Metabolism: Comparative Studies Using CYP2E1-Null and Wild-Type Mice

    J Pharmacol Exp Ther May 1, 2003 305:557-564; published ahead of print January 24, 2003, doi:10.1124/jpet.103.049072
    • D. E. Keyler,
    • D. Shoeman,
    • M. G. LeSage,
    • A. D. Calvin,
    • and P. R. Pentel

    Maternal Vaccination Against Nicotine Reduces Nicotine Distribution to Fetal Brain in Rats

    J Pharmacol Exp Ther May 1, 2003 305:587-592; published ahead of print February 11, 2003, doi:10.1124/jpet.102.046805
    • Sayeepriyadarshini Anakk,
    • Chun Ying Ku,
    • Mary Vore,
    • and Henry W. Strobel

    Insights into Gender Bias: Rat Cytochrome P450 3A9

    J Pharmacol Exp Ther May 1, 2003 305:703-709; published ahead of print February 11, 2003, doi:10.1124/jpet.102.048090
    • Marı́a J. Garrido,
    • Onintza Sayar,
    • Cristina Segura,
    • Javier Rapado,
    • Marı́a Carmen Dios-Viéitez,
    • Marı́a Jesús Renedo,
    • and Iñaki F. Trocóniz

    Pharmacokinetic/Pharmacodynamic Modeling of the Antinociceptive Effects of (+)-Tramadol in the Rat: Role of Cytochrome P450 2D Activity

    J Pharmacol Exp Ther May 1, 2003 305:710-718; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047779

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

    • Alberta Bergamo,
    • Gabriele Stocco,
    • Barbara Gava,
    • Moreno Cocchietto,
    • Enzo Alessio,
    • Barbara Serli,
    • Elisabetta Iengo,
    • and Gianni Sava

    Distinct Effects of Dinuclear Ruthenium(III) Complexes on Cell Proliferation and on Cell Cycle Regulation in Human and Murine Tumor Cell Lines

    J Pharmacol Exp Ther May 1, 2003 305:725-732; published ahead of print February 11, 2003, doi:10.1124/jpet.102.047803

Errata

  • Correction to “α4β7/α4β1Dual Integrin Antagonists Block α4β7-Dependent Adhesion under Shear Flow”

    J Pharmacol Exp Ther May 1, 2003 305:796

  • Correction to “Up-Regulation of Regulator of G Protein Signaling 4 Expression in a Model of Neuropathic Pain and Insensitivity to Morphine”

    J Pharmacol Exp Ther May 1, 2003 305:797

  • Correction to “Structural Requirements for Functional Interaction of Glutathione Tripeptide Analogs with the Human Multidrug Resistance Protein 1 (MRP1)”

    J Pharmacol Exp Ther May 1, 2003 305:798
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This Issue

May 2003; 305 (2)
Cover
  1. PERSPECTIVES IN PHARMACOLOGY
  2. INFLAMMATION AND IMMUNOPHARMACOLOGY
  3. CARDIOVASCULAR
  4. NEUROPHARMACOLOGY
  5. GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  6. CELLULAR AND MOLECULAR
  7. ENDOCRINE AND REPRODUCTIVE
  8. BEHAVIORAL PHARMACOLOGY
  9. ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  10. CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  11. Errata

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