Table of Contents

November 1999; 291 (2)

Articles

Select this article
- Katrin Palm,
- Kristina Luthman,
- Jenny Ros,
- Johan Gråsjö,
- and Per Artursson
Effect of Molecular Charge on Intestinal Epithelial Drug Transport: pH-Dependent Transport of Cationic Drugs
J Pharmacol Exp Ther November 1, 1999 291:435-443
Select this article
- Heather S. Hain,
- John K. Belknap,
- and Jeffrey S. Mogil
Pharmacogenetic Evidence for the Involvement of 5-Hydroxytryptamine (Serotonin)-1B Receptors in the Mediation of Morphine Antinociceptive Sensitivity
J Pharmacol Exp Ther November 1, 1999 291:444-449
Select this article
- Harald Hofer,
- Guan-min Ho,
- Meinrad Peterlik,
- Milan R. Uskokovic,
- Jae Kyoo Lee,
- M. Christina White,
- Gary H. Posner,
- and Heide S. Cross
Biological Effects of 1α-Hydroxy- and 1β-(Hydroxymethyl)-Vitamin D Compounds Relevant for Potential Colorectal Cancer Therapy
J Pharmacol Exp Ther November 1, 1999 291:450-455
Select this article
- Neil C. E. Smith and
- Roberto Levi
LLC-PK₁ Cells Stably Expressing the Human Norepinephrine Transporter: A Functional Model of Carrier-Mediated Norepinephrine Release in Protracted Myocardial Ischemia
J Pharmacol Exp Ther November 1, 1999 291:456-463
Select this article
- Taiji Furukawa,
- Takeshi Yamakawa,
- Takayuki Midera,
- Toshio Sagawa,
- Yasuo Mori,
- and Toshihide Nukada
Selectivities of Dihydropyridine Derivatives in Blocking Ca²⁺ Channel Subtypes Expressed in XenopusOocytes
J Pharmacol Exp Ther November 1, 1999 291:464-473
Select this article
- Klaus J. Wirth,
- Björn Rosenstein,
- Jörg Uhde,
- Heinrich C. Englert,
- Andreas E. Busch,
- and Bernward A. Schölkens
ATP-Sensitive Potassium Channel Blocker HMR 1883 Reduces Mortality and Ischemia-Associated Electrocardiographic Changes in Pigs with Coronary Occlusion
J Pharmacol Exp Ther November 1, 1999 291:474-481
Select this article
- Marc N. Potenza,
- Stephen J. Gold,
- Alison Roby-Shemkowitz,
- Michael R. Lerner,
- and Eric J. Nestler
Effects of Regulators of G Protein-Signaling Proteins on the Functional Response of the μ-Opioid Receptor in a Melanophore-Based Assay
J Pharmacol Exp Ther November 1, 1999 291:482-491
Select this article
- Lawrence H. Lash,
- David A. Putt,
- and Rudolfs K. Zalups
Influence of Exogenous Thiols on Inorganic Mercury-Induced Injury in Renal Proximal and Distal Tubular Cells from Normal and Uninephrectomized Rats
J Pharmacol Exp Ther November 1, 1999 291:492-502
Select this article
- J. L. Zeiders,
- F. J. Seidler,
- and T. A. Slotkin
Agonist-Induced Sensitization of β-Adrenoceptor Signaling in Neonatal Rat Heart: Expression and Catalytic Activity of Adenylyl Cyclase
J Pharmacol Exp Ther November 1, 1999 291:503-510
Select this article
- R. John MacLeod,
- P. Lembessis,
- J. R. Hamilton,
- and William S. Powell
5-Oxo-6,8,11,14-eicosatetraenoic Acid Stimulates Isotonic Volume Reduction of Guinea Pig Jejunal Crypt Epithelial Cells
J Pharmacol Exp Ther November 1, 1999 291:511-516
Select this article
- Shaoheng He,
- Marianna D. A. Gaça,
- Alan R. McEuen,
- and Andrew F. Walls
Inhibitors of Chymase as Mast Cell-Stabilizing Agents: Contribution of Chymase in the Activation of Human Mast Cells
J Pharmacol Exp Ther November 1, 1999 291:517-523
Select this article
- Jennifer Case and
- Cathy A. Davison
Estrogen Alters Relative Contributions of Nitric Oxide and Cyclooxygenase Products to Endothelium-Dependent Vasodilation
J Pharmacol Exp Ther November 1, 1999 291:524-530
Select this article
- Elena H. Chartoff,
- Raymond P. Ward,
- and Daniel M. Dorsa
Role of Adenosine andN-Methyl-d-aspartate Receptors in Mediating Haloperidol-Induced Gene Expression and Catalepsy
J Pharmacol Exp Ther November 1, 1999 291:531-537
Select this article
- Peter Dobelis,
- James E. Madl,
- James A. Pfister,
- Gary D. Manners,
- and John P. Walrond
Effects of Delphinium Alkaloids on Neuromuscular Transmission
J Pharmacol Exp Ther November 1, 1999 291:538-546
Select this article
- Metin Bagli,
- Richard Süverkrüp,
- Ralph Quadflieg,
- Gereon Höflich,
- Siegfried Kasper,
- Hans-Jürgen Möller,
- Michael Langer,
- Uwe Barlage,
- and Marie Luise Rao
Pharmacokinetic-Pharmacodynamic Modeling of Tolerance to the Prolactin-Secreting Effect of Chlorprothixene after Different Modes of Drug Administration
J Pharmacol Exp Ther November 1, 1999 291:547-554
Select this article
- Carlotta E. Groves and
- Mark N. Morales
Chlorotrifluoroethylcysteine Interaction with Rabbit Proximal Tubule Cell Basolateral Membrane Organic Anion Transport and Apical Membrane Amino Acid Transport
J Pharmacol Exp Ther November 1, 1999 291:555-561
Select this article
- Yulong Li,
- Toshiaki Sato,
- and Makoto Arita
Bepridil Blunts the Shortening of Action Potential Duration Caused by Metabolic Inhibition via Blockade of ATP-Sensitive K⁺ Channels and Na⁺-Activated K⁺Channels
J Pharmacol Exp Ther November 1, 1999 291:562-568
Select this article
- John Smeda,
- Sudesh Vasdev,
- and Shelley R. King
Effect of Poststroke Captopril Treatment on Mortality Associated with Hemorrhagic Stroke in Stroke-Prone Rats
J Pharmacol Exp Ther November 1, 1999 291:569-575
Select this article
- Marianna E. Jung,
- Cleatus J. Wallis,
- Michael B. Gatch,
- and Harbans Lal
Sex Differences in the Pentylenetetrazol-Like Stimulus Induced by Ethanol Withdrawal
J Pharmacol Exp Ther November 1, 1999 291:576-582
Select this article
- Laurent Loufrani,
- Daniel Henrion,
- Dominique Chansel,
- Raymond Ardaillou,
- and Bernard I. Levy
Functional Evidence for an Angiotensin IV Receptor in Rat Resistance Arteries
J Pharmacol Exp Ther November 1, 1999 291:583-588
Select this article
- Nobuyuki Ohte,
- Che-Ping Cheng,
- Makoto Suzuki,
- and William C. Little
Effects of Atrial Natriuretic Peptide on Left Ventricular Performance in Conscious Dogs Before and After Pacing-Induced Heart Failure
J Pharmacol Exp Ther November 1, 1999 291:589-595
Select this article
- Ronald L. George,
- Xiang Wu,
- Wei Huang,
- You-Jun Fei,
- Frederick H. Leibach,
- and Vadivel Ganapathy
Molecular Cloning and Functional Characterization of a Polyspecific Organic Anion Transporter from Caenorhabditis elegans
J Pharmacol Exp Ther November 1, 1999 291:596-603
Select this article
- Kensuke Orito,
- Takashi Imaizumi,
- Kenji Yoshida,
- Hiroyuki Fujiki,
- Masami Kishi,
- Shuji Teramoto,
- Michinori Tanaka,
- Hiroshi Shimizu,
- Michiaki Tominaga,
- Yukio Kimura,
- Junichi Kambayashi,
- and Toyoki Mori
Mechanisms of Action of OPC-28326, a Selective Hindlimb Vasodilator
J Pharmacol Exp Ther November 1, 1999 291:604-611
Select this article
- Michael W. Lark,
- George B. Stroup,
- Shing Mei Hwang,
- Ian E. James,
- David J. Rieman,
- Fred H. Drake,
- Jeremy N. Bradbeer,
- Ashwini Mathur,
- Karl F. Erhard,
- Kenneth A. Newlander,
- Stephen T. Ross,
- Kevin L. Salyers,
- Brian R. Smith,
- William H. Miller,
- William F. Huffman,
- and Maxine Gowen
Design and Characterization of Orally Active Arg-Gly-Asp Peptidomimetic Vitronectin Receptor Antagonist SB 265123 for Prevention of Bone Loss in Osteoporosis
J Pharmacol Exp Ther November 1, 1999 291:612-617
Select this article
- Sean D. McAllister,
- Graeme Griffin,
- Leslie S. Satin,
- and Mary E. Abood
Cannabinoid Receptors Can Activate and Inhibit G Protein-Coupled Inwardly Rectifying Potassium Channels in a Xenopus Oocyte Expression System
J Pharmacol Exp Ther November 1, 1999 291:618-626
Select this article
- Isabelle Dumont,
- Xin Hou,
- Pierre Hardy,
- Krishna G. Peri,
- Martin Beauchamp,
- Taline Najarian,
- Stéphane Molotchnikoff,
- Daya R. Varma,
- and Sylvain Chemtob
Developmental Regulation of Endothelial Nitric Oxide Synthase in Cerebral Vessels of Newborn Pig by Prostaglandin E₂
J Pharmacol Exp Ther November 1, 1999 291:627-633
Select this article
- Satoru Takahashi,
- Norihiro Kobayashi,
- and Susumu Okabe
Regulation by Endogenous Interleukin-1 of mRNA Expression of Healing-Related Factors in Gastric Ulcers in Rats
J Pharmacol Exp Ther November 1, 1999 291:634-641
Select this article
- Titti Martinsson,
- Tryggve Ljung,
- Carlos Rubio,
- and Per M. Hellström
Beneficial Effects of Ropivacaine in Rat Experimental Colitis
J Pharmacol Exp Ther November 1, 1999 291:642-647
Select this article
- Sylvie Chalon,
- Lucette Garreau,
- Patrick Emond,
- Luc Zimmer,
- Marie-Paule Vilar,
- Jean-Claude Besnard,
- and Denis Guilloteau
Pharmacological Characterization of (E)-N-(3-iodoprop-2-enyl)-2β-Carbomethoxy-3β-(4′-methylphenyl)nortropane as a Selective and Potent Inhibitor of the Neuronal Dopamine Transporter
J Pharmacol Exp Ther November 1, 1999 291:648-654
Select this article
- Travis W. Hein,
- Luiz Belardinelli,
- and Lih Kuo
Adenosine A_2A Receptors Mediate Coronary Microvascular Dilation to Adenosine: Role of Nitric Oxide and ATP-Sensitive Potassium Channels
J Pharmacol Exp Ther November 1, 1999 291:655-664
Select this article
- William A. Banks
Characterization of Interleukin-1α Binding to Mouse Brain Endothelial Cells
J Pharmacol Exp Ther November 1, 1999 291:665-670
Select this article
- E. E. Daniel,
- R. Dale Brown,
- Y. F. Wang,
- A. M. Low,
- H. Lu-Chao,
- and C.-Y. Kwan
α-Adrenoceptors in Canine Mesenteric Artery Are Predominantly 1A Subtype: Pharmacological and Immunochemical Evidence
J Pharmacol Exp Ther November 1, 1999 291:671-679
Select this article
- Scott A. Wadsworth,
- Druie E. Cavender,
- Scott A. Beers,
- Praful Lalan,
- Peter H. Schafer,
- Elizabeth A. Malloy,
- Wei Wu,
- Bohumila Fahmy,
- Gilbert C. Olini,
- Janet E. Davis,
- J. Lee Pellegrino-Gensey,
- Michael P. Wachter,
- and John J. Siekierka
RWJ 67657, a Potent, Orally Active Inhibitor of p38 Mitogen-Activated Protein Kinase
J Pharmacol Exp Ther November 1, 1999 291:680-687
Select this article
- Yogesh Dwivedi and
- Ghanshyam N. Pandey
Effects of Treatment with Haloperidol, Chlorpromazine, and Clozapine on Protein Kinase C (PKC) and Phosphoinositide-Specific Phospholipase C (PI-PLC) Activity and on mRNA and Protein Expression of PKC and PLC Isozymes in Rat Brain
J Pharmacol Exp Ther November 1, 1999 291:688-704
Select this article
- Kyoko Sawada,
- Tomohiro Terada,
- Hideyuki Saito,
- Yukiya Hashimoto,
- and Ken-Ichi Inui
Recognition of l-Amino Acid Ester Compounds by Rat Peptide Transporters PEPT1 and PEPT2
J Pharmacol Exp Ther November 1, 1999 291:705-709
Select this article
- Kouichi Tanonaka,
- Taku Taguchi,
- Miki Koshimizu,
- Tsuyoshi Ando,
- Tomohiro Morinaka,
- Tomoya Yogo,
- Fusako Konishi,
- and Satoshi Takeo
Role of an ATP-Sensitive Potassium Channel Opener, YM934, in Mitochondrial Energy Production in Ischemic/Reperfused Heart
J Pharmacol Exp Ther November 1, 1999 291:710-716
Select this article
- Lars Börjesson,
- Svante Nordgren,
- and Dick S. Delbro
K⁺-Induced Neurogenic Relaxation of Rat Distal Colon
J Pharmacol Exp Ther November 1, 1999 291:717-724
Select this article
- Leslie D. Napier,
- Sandra C. Roerig,
- Darice A. Yoshishige,
- Barbara A. Barron,
- and James L. Caffrey
Canine Cardiac Muscarinic Receptors, G Proteins, and Adenylate Cyclase after Long-Term Morphine
J Pharmacol Exp Ther November 1, 1999 291:725-732
Select this article
- B. C. Yang,
- D. S. Zander,
- and J. L. Mehta
Hypoxia-Reoxygenation-Induced Apoptosis in Cultured Adult Rat Myocytes and the Protective Effect of Platelets and Transforming Growth Factor-β₁
J Pharmacol Exp Ther November 1, 1999 291:733-738
Select this article
- Vincent A. Pollack,
- Douglas M. Savage,
- Deborah A. Baker,
- Konstantinos E. Tsaparikos,
- Donald E. Sloan,
- James D. Moyer,
- Elsa G. Barbacci,
- Leslie R. Pustilnik,
- Teresa A. Smolarek,
- John A. Davis,
- Madhur P. Vaidya,
- Lee D. Arnold,
- John L. Doty,
- Kenneth K. Iwata,
- and Michael J. Morin
Inhibition of Epidermal Growth Factor Receptor-Associated Tyrosine Phosphorylation in Human Carcinomas with CP-358,774: Dynamics of Receptor Inhibition In Situ and Antitumor Effects in Athymic Mice
J Pharmacol Exp Ther November 1, 1999 291:739-748
Select this article
- Qin Mei,
- Cuyue Tang,
- Carol Assang,
- Yuh Lin,
- Donald Slaughter,
- A. David Rodrigues,
- Thomas A. Baillie,
- Thomas H. Rushmore,
- and Magang Shou
Role of a Potent Inhibitory Monoclonal Antibody to Cytochrome P-450 3A4 in Assessment of Human Drug Metabolism
J Pharmacol Exp Ther November 1, 1999 291:749-759
Select this article
- Qingbo Tang,
- Ronnie Gandhoke,
- Andrew Burritt,
- Victor J. Hruby,
- Frank Porreca,
- and Josephine Lai
High-Affinity Interaction of (des-Tyrosyl)Dynorphin A(2-17) with NMDA Receptors
J Pharmacol Exp Ther November 1, 1999 291:760-765
Select this article
- Qiangrong Liang,
- Edward C. Carlson,
- Anthony J. Borgerding,
- and Paul N. Epstein
A Transgenic Model of Acetaldehyde Overproduction Accelerates Alcohol Cardiomyopathy
J Pharmacol Exp Ther November 1, 1999 291:766-772
Select this article
- Shijie Sun,
- Max Harry Weil,
- Wanchun Tang,
- Heitor P. Povoas,
- and Earl Mason
Combined Effects of Buffer and Adrenergic Agents on Postresuscitation Myocardial Function
J Pharmacol Exp Ther November 1, 1999 291:773-777
Select this article
- Rikiya Ohashi,
- Ikumi Tamai,
- Hikaru Yabuuchi,
- Jun-Ichi Nezu,
- Asuka Oku,
- Yoshimichi Sai,
- Miyuki Shimane,
- and Akira Tsuji
Na⁺-Dependent Carnitine Transport by Organic Cation Transporter (OCTN2): Its Pharmacological and Toxicological Relevance
J Pharmacol Exp Ther November 1, 1999 291:778-784
Select this article
- Jessica C. Brimecombe,
- William K. Potthoff,
- and Elias Aizenman
A Critical Role of theN-Methyl-d-aspartate (NMDA) Receptor Subunit (NR) 2A in the Expression of Redox Sensitivity of NR1/NR2A Recombinant NMDA Receptors
J Pharmacol Exp Ther November 1, 1999 291:785-792
Select this article
- Rainer Büscher,
- Volker Herrmann,
- Kevin M. Ring,
- Mala T. Kailasam,
- Daniel T. O’Connor,
- Robert J. Parmer,
- and Paul A. Insel
Variability in Phenylephrine Response and Essential Hypertension: A Search for Human α_1B-Adrenergic Receptor Polymorphisms
J Pharmacol Exp Ther November 1, 1999 291:793-798
Select this article
- James H. McElmurray III,
- Rupak Mukherjee,
- R. Brent New,
- Angela C. Sampson,
- Mary K. King,
- Jennifer W. Hendrick,
- Aron Goldberg,
- Thomas J. Peterson,
- Hussein Hallak,
- Michael R. Zile,
- and Francis G. Spinale
Angiotensin-Converting Enzyme and Matrix Metalloproteinase Inhibition with Developing Heart Failure: Comparative Effects on Left Ventricular Function and Geometry
J Pharmacol Exp Ther November 1, 1999 291:799-811
Select this article
- Roy D. Schwarz,
- Michael J. Callahan,
- Linda L. Coughenour,
- Melvin R. Dickerson,
- Jack J. Kinsora,
- William J. Lipinski,
- Charlotte A. Raby,
- Carolyn J. Spencer,
- and Haile Tecle
Milameline (CI-979/RU35926): A Muscarinic Receptor Agonist with Cognition-Activating Properties: Biochemical and In Vivo Characterization
J Pharmacol Exp Ther November 1, 1999 291:812-822
Select this article
- Mohammad A. Khoyi,
- Lisa G. Gregory,
- Andrew D. Smith,
- Kathleen D. Keef,
- and David P. Westfall
An Unusual Ca²⁺ Entry Pathway Activated by Protein Kinase C in Dog Splenic Artery
J Pharmacol Exp Ther November 1, 1999 291:823-828
Select this article
- You-Yi Zhang,
- Kai-Ming Xu,
- and Chide Han
α₁-Adrenoceptor Subtypes Mediating Inotropic Responses in Rat Heart
J Pharmacol Exp Ther November 1, 1999 291:829-836
Select this article
- Chen-ni Chin,
- James W. Murphy,
- John W. Huffman,
- and Debra A. Kendall
The Third Transmembrane Helix of the Cannabinoid Receptor Plays a Role in the Selectivity of Aminoalkylindoles for CB2, Peripheral Cannabinoid Receptor
J Pharmacol Exp Ther November 1, 1999 291:837-844
Select this article
- Robert G. Tsushima,
- James E. Kelly,
- Joseph J. Salata,
- Kristine N. Liberty,
- and J. Andrew Wasserstrom
Modification of Cardiac Na⁺ Current by RWJ 24517 and Its Enantiomers in Guinea Pig Ventricular Myocytes
J Pharmacol Exp Ther November 1, 1999 291:845-855
Select this article
- Hiroyuki Inoue,
- Kay Castagnoli,
- Cornelis Van der Schyf,
- Stéphane Mabic,
- Kazuo Igarashi,
- and Neal Castagnoli, Jr
Species-Dependent Differences in Monoamine Oxidase A and B-Catalyzed Oxidation of Various C4 Substituted 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridinyl Derivatives
J Pharmacol Exp Ther November 1, 1999 291:856-864
Select this article
- Yolanda Gutiérrez-Puente,
- Ana M. Tari,
- Clifton Stephens,
- Michael Rosenblum,
- Reyes Tamez Guerra,
- and Gabriel Lopez-Berestein
Safety, Pharmacokinetics, and Tissue Distribution of Liposomal P-Ethoxy Antisense Oligonucleotides Targeted to Bcl-2
J Pharmacol Exp Ther November 1, 1999 291:865-869
Select this article
- Brenda J. Kitchen,
- Asher Moser,
- Elizabeth Lowe,
- Frank M. Balis,
- Brigitte Widemann,
- Lawrence Anderson,
- John Strong,
- Susan M. Blaney,
- Stacey L. Berg,
- Michelle O’Brien,
- and Peter C. Adamson
Thioguanine Administered as a Continuous Intravenous Infusion to Pediatric Patients Is Metabolized to the Novel Metabolite 8-Hydroxy-Thioguanine
J Pharmacol Exp Ther November 1, 1999 291:870-874
Select this article
- Anish A. Konkar,
- Sandeep S. Vansal,
- Gamal Shams,
- Paul F. Fraundorfer,
- Wei-Ping Zheng,
- Victor I. Nikulin,
- Joseph De Los Angeles,
- Richard H. Fertel,
- Duane D. Miller,
- and Dennis R. Feller
β-Adrenoceptor Subtype Activities of Trimetoquinol Derivatives: Biochemical Studies on Human β-Adrenoceptors Expressed in Chinese Hamster Ovary Cells
J Pharmacol Exp Ther November 1, 1999 291:875-883
Select this article
- Lidia Serova,
- Emil Danailov,
- Firas Chamas,
- and Esther L. Sabban
Nicotine Infusion Modulates Immobilization Stress-Triggered Induction of Gene Expression of Rat Catecholamine Biosynthetic Enzymes
J Pharmacol Exp Ther November 1, 1999 291:884-892
Select this article
- Jian Mu,
- Shou-yuan Zhuang,
- M. Todd Kirby,
- Robert E. Hampson,
- and Sam A. Deadwyler
Cannabinoid Receptors Differentially Modulate Potassium A and D Currents in Hippocampal Neurons in Culture
J Pharmacol Exp Ther November 1, 1999 291:893-902
Select this article
- Steven W. Kerr,
- Walter W. Wolyniec,
- Zoran Filipovic,
- Suzanne G. Nodop,
- Frank Braza,
- Raymond J. Winquist,
- and Thomas C. Noonan
Repeated Measurement of Intestinal Permeability as an Assessment of Colitis Severity in HLA-B27 Transgenic Rats
J Pharmacol Exp Ther November 1, 1999 291:903-910
Select this article
- Mahin D. Maines,
- Vulapali S. Raju,
- and Nariman Panahian
Spin Trap (N-t-butyl-α-phenylnitrone)-Mediated Suprainduction of Heme Oxygenase-1 in Kidney Ischemia/Reperfusion Model: Role of the Oxygenase in Protection against Oxidative Injury
J Pharmacol Exp Ther November 1, 1999 291:911-919
Select this article
- Asad Junaid,
- Li Cui,
- S. Brian Penner,
- and Donald D. Smyth
Regulation of Aquaporin-2 Expression by the α₂-Adrenoceptor Agonist Clonidine in the Rat
J Pharmacol Exp Ther November 1, 1999 291:920-923

Current Issue

November 2009, 331 (2)

Articles

Effect of Molecular Charge on Intestinal Epithelial Drug Transport: pH-Dependent Transport of Cationic Drugs

Pharmacogenetic Evidence for the Involvement of 5-Hydroxytryptamine (Serotonin)-1B Receptors in the Mediation of Morphine Antinociceptive Sensitivity

Biological Effects of 1α-Hydroxy- and 1β-(Hydroxymethyl)-Vitamin D Compounds Relevant for Potential Colorectal Cancer Therapy

LLC-PK1 Cells Stably Expressing the Human Norepinephrine Transporter: A Functional Model of Carrier-Mediated Norepinephrine Release in Protracted Myocardial Ischemia

Selectivities of Dihydropyridine Derivatives in Blocking Ca2+ Channel Subtypes Expressed in XenopusOocytes

ATP-Sensitive Potassium Channel Blocker HMR 1883 Reduces Mortality and Ischemia-Associated Electrocardiographic Changes in Pigs with Coronary Occlusion

Effects of Regulators of G Protein-Signaling Proteins on the Functional Response of the μ-Opioid Receptor in a Melanophore-Based Assay

Influence of Exogenous Thiols on Inorganic Mercury-Induced Injury in Renal Proximal and Distal Tubular Cells from Normal and Uninephrectomized Rats

Agonist-Induced Sensitization of β-Adrenoceptor Signaling in Neonatal Rat Heart: Expression and Catalytic Activity of Adenylyl Cyclase

5-Oxo-6,8,11,14-eicosatetraenoic Acid Stimulates Isotonic Volume Reduction of Guinea Pig Jejunal Crypt Epithelial Cells

Inhibitors of Chymase as Mast Cell-Stabilizing Agents: Contribution of Chymase in the Activation of Human Mast Cells

Estrogen Alters Relative Contributions of Nitric Oxide and Cyclooxygenase Products to Endothelium-Dependent Vasodilation

Role of Adenosine andN-Methyl-d-aspartate Receptors in Mediating Haloperidol-Induced Gene Expression and Catalepsy

Effects of Delphinium Alkaloids on Neuromuscular Transmission

Pharmacokinetic-Pharmacodynamic Modeling of Tolerance to the Prolactin-Secreting Effect of Chlorprothixene after Different Modes of Drug Administration

Chlorotrifluoroethylcysteine Interaction with Rabbit Proximal Tubule Cell Basolateral Membrane Organic Anion Transport and Apical Membrane Amino Acid Transport

Bepridil Blunts the Shortening of Action Potential Duration Caused by Metabolic Inhibition via Blockade of ATP-Sensitive K+ Channels and Na+-Activated K+Channels

Effect of Poststroke Captopril Treatment on Mortality Associated with Hemorrhagic Stroke in Stroke-Prone Rats

Sex Differences in the Pentylenetetrazol-Like Stimulus Induced by Ethanol Withdrawal

Functional Evidence for an Angiotensin IV Receptor in Rat Resistance Arteries

Effects of Atrial Natriuretic Peptide on Left Ventricular Performance in Conscious Dogs Before and After Pacing-Induced Heart Failure

Molecular Cloning and Functional Characterization of a Polyspecific Organic Anion Transporter from Caenorhabditis elegans

Mechanisms of Action of OPC-28326, a Selective Hindlimb Vasodilator

Design and Characterization of Orally Active Arg-Gly-Asp Peptidomimetic Vitronectin Receptor Antagonist SB 265123 for Prevention of Bone Loss in Osteoporosis

Cannabinoid Receptors Can Activate and Inhibit G Protein-Coupled Inwardly Rectifying Potassium Channels in a Xenopus Oocyte Expression System

Developmental Regulation of Endothelial Nitric Oxide Synthase in Cerebral Vessels of Newborn Pig by Prostaglandin E2

Regulation by Endogenous Interleukin-1 of mRNA Expression of Healing-Related Factors in Gastric Ulcers in Rats

Beneficial Effects of Ropivacaine in Rat Experimental Colitis

Pharmacological Characterization of (E)-N-(3-iodoprop-2-enyl)-2β-Carbomethoxy-3β-(4′-methylphenyl)nortropane as a Selective and Potent Inhibitor of the Neuronal Dopamine Transporter

Adenosine A2A Receptors Mediate Coronary Microvascular Dilation to Adenosine: Role of Nitric Oxide and ATP-Sensitive Potassium Channels

Characterization of Interleukin-1α Binding to Mouse Brain Endothelial Cells

α-Adrenoceptors in Canine Mesenteric Artery Are Predominantly 1A Subtype: Pharmacological and Immunochemical Evidence

RWJ 67657, a Potent, Orally Active Inhibitor of p38 Mitogen-Activated Protein Kinase

Effects of Treatment with Haloperidol, Chlorpromazine, and Clozapine on Protein Kinase C (PKC) and Phosphoinositide-Specific Phospholipase C (PI-PLC) Activity and on mRNA and Protein Expression of PKC and PLC Isozymes in Rat Brain

Recognition of l-Amino Acid Ester Compounds by Rat Peptide Transporters PEPT1 and PEPT2

Role of an ATP-Sensitive Potassium Channel Opener, YM934, in Mitochondrial Energy Production in Ischemic/Reperfused Heart

K+-Induced Neurogenic Relaxation of Rat Distal Colon

Canine Cardiac Muscarinic Receptors, G Proteins, and Adenylate Cyclase after Long-Term Morphine

Hypoxia-Reoxygenation-Induced Apoptosis in Cultured Adult Rat Myocytes and the Protective Effect of Platelets and Transforming Growth Factor-β1

Inhibition of Epidermal Growth Factor Receptor-Associated Tyrosine Phosphorylation in Human Carcinomas with CP-358,774: Dynamics of Receptor Inhibition In Situ and Antitumor Effects in Athymic Mice

Role of a Potent Inhibitory Monoclonal Antibody to Cytochrome P-450 3A4 in Assessment of Human Drug Metabolism

High-Affinity Interaction of (des-Tyrosyl)Dynorphin A(2-17) with NMDA Receptors

A Transgenic Model of Acetaldehyde Overproduction Accelerates Alcohol Cardiomyopathy

Combined Effects of Buffer and Adrenergic Agents on Postresuscitation Myocardial Function

Na+-Dependent Carnitine Transport by Organic Cation Transporter (OCTN2): Its Pharmacological and Toxicological Relevance

A Critical Role of theN-Methyl-d-aspartate (NMDA) Receptor Subunit (NR) 2A in the Expression of Redox Sensitivity of NR1/NR2A Recombinant NMDA Receptors

Variability in Phenylephrine Response and Essential Hypertension: A Search for Human α1B-Adrenergic Receptor Polymorphisms

Angiotensin-Converting Enzyme and Matrix Metalloproteinase Inhibition with Developing Heart Failure: Comparative Effects on Left Ventricular Function and Geometry

Milameline (CI-979/RU35926): A Muscarinic Receptor Agonist with Cognition-Activating Properties: Biochemical and In Vivo Characterization

An Unusual Ca2+ Entry Pathway Activated by Protein Kinase C in Dog Splenic Artery

α1-Adrenoceptor Subtypes Mediating Inotropic Responses in Rat Heart

The Third Transmembrane Helix of the Cannabinoid Receptor Plays a Role in the Selectivity of Aminoalkylindoles for CB2, Peripheral Cannabinoid Receptor

Modification of Cardiac Na+ Current by RWJ 24517 and Its Enantiomers in Guinea Pig Ventricular Myocytes

Species-Dependent Differences in Monoamine Oxidase A and B-Catalyzed Oxidation of Various C4 Substituted 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridinyl Derivatives

Safety, Pharmacokinetics, and Tissue Distribution of Liposomal P-Ethoxy Antisense Oligonucleotides Targeted to Bcl-2

Thioguanine Administered as a Continuous Intravenous Infusion to Pediatric Patients Is Metabolized to the Novel Metabolite 8-Hydroxy-Thioguanine

β-Adrenoceptor Subtype Activities of Trimetoquinol Derivatives: Biochemical Studies on Human β-Adrenoceptors Expressed in Chinese Hamster Ovary Cells

Nicotine Infusion Modulates Immobilization Stress-Triggered Induction of Gene Expression of Rat Catecholamine Biosynthetic Enzymes

Cannabinoid Receptors Differentially Modulate Potassium A and D Currents in Hippocampal Neurons in Culture

Repeated Measurement of Intestinal Permeability as an Assessment of Colitis Severity in HLA-B27 Transgenic Rats

Spin Trap (N-t-butyl-α-phenylnitrone)-Mediated Suprainduction of Heme Oxygenase-1 in Kidney Ischemia/Reperfusion Model: Role of the Oxygenase in Protection against Oxidative Injury

Regulation of Aquaporin-2 Expression by the α2-Adrenoceptor Agonist Clonidine in the Rat

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LLC-PK₁ Cells Stably Expressing the Human Norepinephrine Transporter: A Functional Model of Carrier-Mediated Norepinephrine Release in Protracted Myocardial Ischemia

Selectivities of Dihydropyridine Derivatives in Blocking Ca²⁺ Channel Subtypes Expressed in XenopusOocytes

Bepridil Blunts the Shortening of Action Potential Duration Caused by Metabolic Inhibition via Blockade of ATP-Sensitive K⁺ Channels and Na⁺-Activated K⁺Channels

Developmental Regulation of Endothelial Nitric Oxide Synthase in Cerebral Vessels of Newborn Pig by Prostaglandin E₂

Adenosine A_2A Receptors Mediate Coronary Microvascular Dilation to Adenosine: Role of Nitric Oxide and ATP-Sensitive Potassium Channels

K⁺-Induced Neurogenic Relaxation of Rat Distal Colon

Hypoxia-Reoxygenation-Induced Apoptosis in Cultured Adult Rat Myocytes and the Protective Effect of Platelets and Transforming Growth Factor-β₁

Na⁺-Dependent Carnitine Transport by Organic Cation Transporter (OCTN2): Its Pharmacological and Toxicological Relevance

Variability in Phenylephrine Response and Essential Hypertension: A Search for Human α_1B-Adrenergic Receptor Polymorphisms

An Unusual Ca²⁺ Entry Pathway Activated by Protein Kinase C in Dog Splenic Artery

α₁-Adrenoceptor Subtypes Mediating Inotropic Responses in Rat Heart

Modification of Cardiac Na⁺ Current by RWJ 24517 and Its Enantiomers in Guinea Pig Ventricular Myocytes

Regulation of Aquaporin-2 Expression by the α₂-Adrenoceptor Agonist Clonidine in the Rat