Table of Contents

April 1999; 289 (1)

Articles

Select this article
- A. Jenny Versluis,
- Erik T. Rump,
- Patrick C. N. Rensen,
- Theo J. C. van Berkel,
- and Martin K. Bijsterbosch
Stable Incorporation of a Lipophilic Daunorubicin Prodrug into Apolipoprotein E-Exposing Liposomes Induces Uptake of Prodrug via Low-Density Lipoprotein Receptor in Vivo
J Pharmacol Exp Ther April 1, 1999 289:1-7
Select this article
- Ronald J. Tallarida,
- Dennis J. Stone, Jr.,
- Jeffrey D. McCary,
- and Robert B. Raffa
Response Surface Analysis of Synergism Between Morphine and Clonidine
J Pharmacol Exp Ther April 1, 1999 289:8-13
Select this article
- Elizabeth A. Pehek
Comparison of Effects of Haloperidol Administration on Amphetamine-Stimulated Dopamine Release in the Rat Medial Prefrontal Cortex and Dorsal Striatum
J Pharmacol Exp Ther April 1, 1999 289:14-23
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- Tatsuo Watanabe,
- Yoshiyuki Sakata,
- Takashi Fujioka,
- Daikai Sadamitsu,
- and Tsuyoshi Maekawa
Glucocorticoid Enhances Interleukin-1-Induced Pressor Response in Freely Moving Rats Through Its Effect on Nitric Oxide Release
J Pharmacol Exp Ther April 1, 1999 289:24-30
Select this article
- Torben Leo Nielsen,
- Birgitte Buur Rasmussen,
- Jean-Pierre Flinois,
- Philippe Beaune,
- and Kim Brøsen
In Vitro Metabolism of Quinidine: The (3S)-3-Hydroxylation of Quinidine Is a Specific Marker Reaction for Cytochrome P-4503A4 Activity in Human Liver Microsomes
J Pharmacol Exp Ther April 1, 1999 289:31-37
Select this article
- Bryan K. Tolliver,
- Lauren B. Ho,
- Lisa M. Fox,
- and S. Paul Berger
Necessary Role for Ventral Tegmental Area Adenylate Cyclase and Protein Kinase A in Induction of Behavioral Sensitization to Intraventral Tegmental Area Amphetamine
J Pharmacol Exp Ther April 1, 1999 289:38-47
Select this article
- Robert N. Willette,
- Nambi Aiyar,
- Tian-Li Yue,
- Marcus P. Mitchell,
- Jyoti Disa,
- Barbara L. Storer,
- Diane P. Naselsky,
- Jeffery M. Stadel,
- Eliot H. Ohlstein,
- and Robert R. Ruffolo, Jr.
In Vitro and In Vivo Characterization of Intrinsic Sympathomimetic Activity in Normal and Heart Failure Rats
J Pharmacol Exp Ther April 1, 1999 289:48-53
Select this article
- Ratna Sircar and
- David Kim
Female Gonadal Hormones Differentially Modulate Cocaine-Induced Behavioral Sensitization in Fischer, Lewis, and Sprague-Dawley Rats
J Pharmacol Exp Ther April 1, 1999 289:54-65
Select this article
- Ken Iseki,
- Mitsuru Sugawara,
- Kaori Sato,
- Imad Naasani,
- Tomohisa Hayakawa,
- Michiya Kobayashi,
- and Katsumi Miyazaki
Multiplicity of the H⁺-Dependent Transport Mechanism of Dipeptide and Anionic β-Lactam Antibiotic Ceftibuten in Rat Intestinal Brush-Border Membrane
J Pharmacol Exp Ther April 1, 1999 289:66-71
Select this article
- Masahiko Kurokawa,
- Purusotam Basnet,
- Mizue Ohsugi,
- Toyoharu Hozumi,
- Shigetoshi Kadota,
- Tsuneo Namba,
- Takashi Kawana,
- and Kimiyasu Shiraki
Anti-Herpes Simplex Virus Activity of Moronic Acid Purified fromRhus javanica In Vitro and In Vivo
J Pharmacol Exp Ther April 1, 1999 289:72-78
Select this article
- Mitsuo Murata,
- Ikumi Tamai,
- Yoshimichi Sai,
- Osamu Nagata,
- Hideo Kato,
- and Akira Tsuji
Carrier-Mediated Lung Distribution of HSR-903, a New Quinolone Antibacterial Agent
J Pharmacol Exp Ther April 1, 1999 289:79-84
Select this article
- William R. Bensch,
- Robert A. Gadski,
- James S. Bean,
- Lisa S. Beavers,
- Robert J. Schmidt,
- David N. Perry,
- Anthony T. Murphy,
- Donald B. McClure,
- Patrick I. Eacho,
- Alan P. Breau,
- Robert A. Archer,
- and Raymond F. Kauffman
Effects of LY295427, a Low-Density Lipoprotein (LDL) Receptor Up-Regulator, on LDL Receptor Gene Transcription and Cholesterol Metabolism in Normal and Hypercholesterolemic Hamsters
J Pharmacol Exp Ther April 1, 1999 289:85-92
Select this article
- Masamichi Kuwajima,
- Hideyoshi Harashima,
- Miyuki Hayashi,
- Saori Ise,
- Masako Sei,
- Kang-mo Lu,
- Hiroshi Kiwada,
- Yuichi Sugiyama,
- and Kenji Shima
Pharmacokinetic Analysis of the Cardioprotective Effect of 3-(2,2,2-Trimethylhydrazinium) Propionate in Mice: Inhibition of Carnitine Transport in Kidney
J Pharmacol Exp Ther April 1, 1999 289:93-102
Select this article
- Hideyuki Hiraishi,
- Tadahito Shimada,
- Kevin J. Ivey,
- and Akira Terano
Role of Antioxidant Defenses Against Ethanol-Induced Damage in Cultured Rat Gastric Epithelial Cells
J Pharmacol Exp Ther April 1, 1999 289:103-109
Select this article
- Bryan K. Tolliver,
- Amy H. Newman,
- Jonathan L. Katz,
- Lauren B. Ho,
- Lisa M. Fox,
- Kang Hsu, Jr.,
- and S. Paul Berger
Behavioral and Neurochemical Effects of the Dopamine Transporter Ligand 4-Chlorobenztropine Alone and in Combination with Cocaine In Vivo
J Pharmacol Exp Ther April 1, 1999 289:110-122
Select this article
- V. Moreno Manzano,
- M. Rodriguez Puyol,
- D. Rodriguez Puyol,
- and F. J. Lucio Cazaña
Tretinoin Prevents Age-Related Renal Changes and Stimulates Antioxidant Defenses in Cultured Renal Mesangial Cells
J Pharmacol Exp Ther April 1, 1999 289:123-132
Select this article
- Yitong Fu,
- Shannon G. Matta,
- and Burt M. Sharp
Local α-Bungarotoxin-Sensitive Nicotinic Receptors Modulate Hippocampal Norepinephrine Release by Systemic Nicotine
J Pharmacol Exp Ther April 1, 1999 289:133-139
Select this article
- Laurent P. Audoly,
- Lijun Ma,
- Igor Feoktistov,
- Stephanie K. de Foe,
- Matthew D. Breyer,
- and Richard M. Breyer
Prostaglandin E-Prostanoid-3 Receptor Activation of Cyclic AMP Response Element-Mediated Gene Transcription
J Pharmacol Exp Ther April 1, 1999 289:140-148
Select this article
- Ryoko Yumoto,
- Teruo Murakami,
- Yuko Nakamoto,
- Risa Hasegawa,
- Junya Nagai,
- and Mikihisa Takano
Transport of Rhodamine 123, a P-Glycoprotein Substrate, across Rat Intestine and Caco-2 Cell Monolayers in the Presence of Cytochrome P-450 3A-Related Compounds
J Pharmacol Exp Ther April 1, 1999 289:149-155
Select this article
- Ralph F. Bosch,
- Gui-Rong Li,
- Rania Gaspo,
- and Stanley Nattel
Electrophysiologic Effects of Chronic Amiodarone Therapy and Hypothyroidism, Alone and in Combination, on Guinea Pig Ventricular Myocytes
J Pharmacol Exp Ther April 1, 1999 289:156-165
Select this article
- Pablo Garcia-Pastor,
- Antonio Randazzo,
- Luigi Gomez-Paloma,
- M. Jose Alcaraz,
- and Miguel Paya
Effects of Petrosaspongiolide M, a Novel Phospholipase A₂ Inhibitor, on Acute and Chronic Inflammation
J Pharmacol Exp Ther April 1, 1999 289:166-172
Select this article
- Daniel R. Kapusta,
- Jaw-Kang Chang,
- and Velga A. Kenigs
Central Administration of [Phe¹Ψ(CH₂-NH)Gly²]Nociceptin(1-13)-NH₂and Orphanin FQ/Nociceptin (OFQ/N) Produce Similar Cardiovascular and Renal Responses in Conscious Rats
J Pharmacol Exp Ther April 1, 1999 289:173-180
Select this article
- L. Iouzalen,
- O. Stepien,
- and P. Marche
Effects of Bay 10–6734 (Embusartan), a New Angiotensin II Type I Receptor Antagonist, on Vascular Smooth Muscle Cell Growth ,
J Pharmacol Exp Ther April 1, 1999 289:181-187
Select this article
- Joachim Neumann,
- Renke Maas,
- Peter Boknı́k,
- Larry R. Jones,
- Norbert Zimmermann,
- and Hasso Scholz
Pharmacological Characterization of Protein Phosphatase Activities in Preparations from Failing Human Hearts
J Pharmacol Exp Ther April 1, 1999 289:188-193
Select this article
- Marta Bosch-Marcé,
- Jorge-Luis Poo,
- Wladimiro Jiménez,
- Nuria Bordas,
- Alberto Leivas,
- Manuel Morales-Ruiz,
- Rosa Maria Muñoz,
- Manuel Pérez,
- Vicente Arroyo,
- Francisca Rivera,
- and Juan Rodés
Comparison of Two Aquaretic Drugs (Niravoline and OPC-31260) in Cirrhotic Rats with Ascites and Water Retention
J Pharmacol Exp Ther April 1, 1999 289:194-201
Select this article
- Zao Dung Ling,
- Heather C. Robie,
- Chong Wai Tong,
- and Paul M. Carvey
Both the Antioxidant and D₃ Agonist Actions of Pramipexole Mediate Its Neuroprotective Actions in Mesencephalic Cultures
J Pharmacol Exp Ther April 1, 1999 289:202-210
Select this article
- S. N. Iyer,
- G. Gurujeyalakshmi,
- and S. N. Giri
Effects of Pirfenidone on Procollagen Gene Expression at the Transcriptional Level in Bleomycin Hamster Model of Lung Fibrosis
J Pharmacol Exp Ther April 1, 1999 289:211-218
Select this article
- Abba J. Kastin and
- Victoria Akerstrom
Orexin A but Not Orexin B Rapidly Enters Brain from Blood by Simple Diffusion
J Pharmacol Exp Ther April 1, 1999 289:219-223
Select this article
- Koichi Yokogawa,
- Yasuhiko Higashi,
- Ikumi Tamai,
- Masaaki Nomura,
- Noriyoshi Hashimoto,
- Hiroko Nikaido,
- Jun-Ichiro Hayakawa,
- Ken-Ichi Miyamoto,
- and Akira Tsuji
Decreased Tissue Distribution of l-Carnitine in Juvenile Visceral Steatosis Mice
J Pharmacol Exp Ther April 1, 1999 289:224-230
Select this article
- Elisabeth Filipski,
- Sophie Amat,
- Guy Lemaigre,
- Marc Vincenti,
- Fabienne Breillout,
- and Francis A. Lévi
Relationship Between Circadian Rhythm of Vinorelbine Toxicity and Efficacy in P388-Bearing Mice
J Pharmacol Exp Ther April 1, 1999 289:231-235
Select this article
- S. L. Yong,
- R. Xu,
- J. G. McLarnon,
- A. B. Zolotoy,
- G. N. Beatch,
- and M. J. A. Walker
RSD1000: A Novel Antiarrhythmic Agent with Increased Potency under Acidic and High-Potassium Conditions
J Pharmacol Exp Ther April 1, 1999 289:236-244
Select this article
- Norio Ishioka and
- Richard D. Bukoski
A Role for N-Arachidonylethanolamine (Anandamide) as the Mediator of Sensory Nerve-Dependent Ca²⁺-Induced Relaxation
J Pharmacol Exp Ther April 1, 1999 289:245-250
Select this article
- Malliga E. Ganapathy,
- Puttur D. Prasad,
- Wei Huang,
- Pankaj Seth,
- Frederick H. Leibach,
- and Vadivel Ganapathy
Molecular and Ligand-Binding Characterization of the ς-Receptor in the Jurkat Human T Lymphocyte Cell Line
J Pharmacol Exp Ther April 1, 1999 289:251-260
Select this article
- John D. Parker,
- Jake J. Thiessen,
- Ray Reilly,
- Jeffrey H. Tong,
- Duncan J. Stewart,
- and A. Shekhar Pandey
Human Endothelin-1 Clearance Kinetics Revealed by a Radiotracer Technique
J Pharmacol Exp Ther April 1, 1999 289:261-265
Select this article
- Nancy R. Zahniser,
- Gaynor A. Larson,
- and Greg A. Gerhardt
In Vivo Dopamine Clearance Rate in Rat Striatum: Regulation by Extracellular Dopamine Concentration and Dopamine Transporter Inhibitors
J Pharmacol Exp Ther April 1, 1999 289:266-277
Select this article
- John K. Weatherspoon and
- Linda L. Werling
Modulation of Amphetamine-Stimulated [³H]Dopamine Release from Rat Pheochromocytoma (PC12) Cells by ς Type 2 Receptors
J Pharmacol Exp Ther April 1, 1999 289:278-284
Select this article
- Suzette M. Evans and
- Roland R. Griffiths
Caffeine Withdrawal: A Parametric Analysis of Caffeine Dosing Conditions
J Pharmacol Exp Ther April 1, 1999 289:285-294
Select this article
- Ann-Maree Duncan,
- Gail M. James,
- Frank Anastasopoulos,
- Athena Kladis,
- Todd A. Briscoe,
- and Duncan J. Campbell
Interaction Between Neutral Endopeptidase and Angiotensin Converting Enzyme Inhibition in Rats with Myocardial Infarction: Effects on Cardiac Hypertrophy and Angiotensin and Bradykinin Peptide Levels
J Pharmacol Exp Ther April 1, 1999 289:295-303
Select this article
- Jay P. McLaughlin,
- Kevin P. Hill,
- Qi Jiang,
- Alice Sebastian,
- Sydney Archer,
- and Jean M. Bidlack
Nitrocinnamoyl and Chlorocinnamoyl Derivatives of Dihydrocodeinone: In Vivo and In Vitro Characterization of μ-Selective Agonist and Antagonist Activity
J Pharmacol Exp Ther April 1, 1999 289:304-311
Select this article
- Anthony P.J. King,
- Karen E. Hall,
- and Robert L. Macdonald
κ- and μ-Opioid Inhibition of N-Type Calcium Currents Is Attenuated by 4β-Phorbol 12-Myristate 13-Acetate and Protein Kinase C in Rat Dorsal Root Ganglion Neurons
J Pharmacol Exp Ther April 1, 1999 289:312-320
Select this article
- Olivier Soriani,
- Frank Le Foll,
- François Roman,
- François P. Monnet,
- Hubert Vaudry,
- and Lionel Cazin
A-Current Down-Modulated by ς Receptor in Frog Pituitary Melanotrope Cells Through a G Protein-Dependent Pathway
J Pharmacol Exp Ther April 1, 1999 289:321-328
Select this article
- Judith van Asperen,
- Olaf van Tellingen,
- Alfred H. Schinkel,
- and Jos H. Beijnen
Comparative Pharmacokinetics of Vinblastine after a 96-Hour Continuous Infusion in Wild-Type Mice and Mice Lacking mdr1a P-Glycoprotein
J Pharmacol Exp Ther April 1, 1999 289:329-333
Select this article
- Theodore A. Slotkin,
- Diane B. Miller,
- Fabio Fumagalli,
- Everett C. McCook,
- Jian Zhang,
- Garth Bissette,
- and Frederic J. Seidler
Modeling Geriatric Depression in Animals: Biochemical and Behavioral Effects of Olfactory Bulbectomy in Young Versus Aged Rats
J Pharmacol Exp Ther April 1, 1999 289:334-345
Select this article
- Nusara Piyapolrungroj,
- Cheng Li,
- Ronald L. Pisoni,
- and David Fleisher
Cimetidine Transport in Brush-Border Membrane Vesicles from Rat Small Intestine
J Pharmacol Exp Ther April 1, 1999 289:346-353
Select this article
- James R. Smith,
- Cheol Kim,
- Heather Kim,
- and Ralph E. Purdy
Precontraction with Elevated Concentrations of Extracellular Potassium Enables both 5-HT_1B and 5-HT_2A“Silent” Receptors in Rabbit Ear Artery
J Pharmacol Exp Ther April 1, 1999 289:354-360
Select this article
- Marina T. Seme,
- Phyllis Summerfelt,
- Michele M. Henry,
- Jay Neitz,
- and Janis T. Eells
Formate-Induced Inhibition of Photoreceptor Function in Methanol Intoxication
J Pharmacol Exp Ther April 1, 1999 289:361-370
Select this article
- Jean-Michel Gries,
- Alain Munafo,
- Herve C. Porchet,
- and Davide Verotta
Down-Regulation Models and Modeling of Testosterone Production Induced by Recombinant Human Choriogonadotropin
J Pharmacol Exp Ther April 1, 1999 289:371-377
Select this article
- Mei-Chuan Ko,
- Eduardo R. Butelman,
- and James H. Woods
Activation of Peripheral κ Opioid Receptors Inhibits Capsaicin-Induced Thermal Nociception in Rhesus Monkeys
J Pharmacol Exp Ther April 1, 1999 289:378-385
Select this article
- William J. Crumb, Jr,
- Nabil Munfakh,
- Herman A. Heck,
- and Lynn H. Harrison, Jr
Fatty Acid Block of the Transient Outward Current in Adult Human Atrium
J Pharmacol Exp Ther April 1, 1999 289:386-391
Select this article
- Steven A. Johnson,
- Nguyen T. Luu,
- Todd A. Herbst,
- Richard Knapp,
- David Lutz,
- Amy Arai,
- Gary A. Rogers,
- and Gary Lynch
Synergistic Interactions between Ampakines and Antipsychotic Drugs
J Pharmacol Exp Ther April 1, 1999 289:392-397
Select this article
- Takaaki Ishine,
- Jun-Ge Yu,
- Yujiro Asada,
- and Tony Jer-Fu Lee
Nitric Oxide Is the Predominant Mediator for Neurogenic Vasodilation in Porcine Pial Veins
J Pharmacol Exp Ther April 1, 1999 289:398-404
Select this article
- Carrie A. Bowen,
- Robert H. Purdy,
- and Kathleen A. Grant
Ethanol-Like Discriminative Stimulus Effects of Endogenous Neuroactive Steroids: Effect of Ethanol Training Dose and Dosing Procedure
J Pharmacol Exp Ther April 1, 1999 289:405-411
Select this article
- Gang Hu,
- Patricia Duffy,
- Chad Swanson,
- M. Behnam Ghasemzadeh,
- and Peter W. Kalivas
The Regulation of Dopamine Transmission by Metabotropic Glutamate Receptors
J Pharmacol Exp Ther April 1, 1999 289:412-416
Select this article
- Adair R. S. Santos,
- Obdúlio G. Miguel,
- Rosendo A. Yunes,
- and João B. Calixto
Antinociceptive Properties of the New Alkaloid,cis-8,10-Di-N-Propyllobelidiol Hydrochloride Dihydrate Isolated from Siphocampylus verticillatus: Evidence for the Mechanism of Action
J Pharmacol Exp Ther April 1, 1999 289:417-426
Select this article
- Mark J. Millan,
- Rudy Schreiber,
- Sabine Monneyron,
- Brigitte Denorme,
- Christophe Melon,
- Sophie Queriaux,
- and Anne Dekeyne
S-16924, a Novel, Potential Antipsychotic with Marked Serotonin_1A Agonist Properties. IV. A Drug Discrimination Comparison with Clozapine
J Pharmacol Exp Ther April 1, 1999 289:427-436
Select this article
- Ken-Ichi Nunoya,
- Tsuyoshi Yokoi,
- Kanzo Kimura,
- Tadashi Kainuma,
- Kunio Satoh,
- Moritoshi Kinoshita,
- and Tetsuya Kamataki
A New CYP2A6 Gene Deletion Responsible for the In Vivo Polymorphic Metabolism of (+)-cis-3,5-Dimethyl-2-(3-pyridyl)thiazolidin-4-one Hydrochloride in Humans
J Pharmacol Exp Ther April 1, 1999 289:437-442
Select this article
- Klaus Thomsen,
- Martin Bak,
- and David G. Shirley
Chronic Lithium Treatment Inhibits Amiloride-Sensitive Sodium Transport in the Rat Distal Nephron
J Pharmacol Exp Ther April 1, 1999 289:443-447
Select this article
- Ailan Guo,
- Peidi Hu,
- Praveen V. Balimane,
- Frederick H. Leibach,
- and Patrick J. Sinko
Interactions of a Nonpeptidic Drug, Valacyclovir, with the Human Intestinal Peptide Transporter (hPEPT1) Expressed in a Mammalian Cell Line
J Pharmacol Exp Ther April 1, 1999 289:448-454
Select this article
- Alexander F. Hoffman and
- Greg A. Gerhardt
Differences in Pharmacological Properties of Dopamine Release Between the Substantia Nigra and Striatum: An In Vivo Electrochemical Study
J Pharmacol Exp Ther April 1, 1999 289:455-463
Select this article
- Gregory W. Sawyer and
- Frederick J. Ehlert
Muscarinic M₃ Receptor Inactivation Reveals a Pertussis Toxin-Sensitive Contractile Response in the Guinea Pig Colon: Evidence for M₂/M₃ Receptor Interactions
J Pharmacol Exp Ther April 1, 1999 289:464-476
Select this article
- Edmond D. Buck,
- Wilhelm G. Lachnit,
- and Isaac N. Pessah
Mechanisms of δ-Hexachlorocyclohexane Toxicity: I. Relationship Between Altered Ventricular Myocyte Contractility and Ryanodine Receptor Function
J Pharmacol Exp Ther April 1, 1999 289:477-485
Select this article
- Edmond D. Buck and
- Isaac N. Pessah
Mechanisms of δ-Hexachlorocyclohexane Toxicity: II. Evidence for Ca²⁺-Dependent K⁺-Selective Ionophore Activity
J Pharmacol Exp Ther April 1, 1999 289:486-493
Select this article
- D. L. DeHaven-Hudkins,
- L. Cortes Burgos,
- J. A. Cassel,
- J. D. Daubert,
- R. N. DeHaven,
- E. Mansson,
- H. Nagasaka,
- G. Yu,
- and T. Yaksh
Loperamide (ADL 2-1294), an Opioid Antihyperalgesic Agent with Peripheral Selectivity
J Pharmacol Exp Ther April 1, 1999 289:494-502
Select this article
- Jacquelynn J. Cook,
- Stephen J. Gardell,
- Marie A. Holahan,
- Gary R. Sitko,
- Gary L. Stump,
- Audrey A. Wallace,
- David B. Gilberto,
- Timothy R. Hare,
- Julie A. Krueger,
- Dona L. Dyer,
- Philip E. J. Sanderson,
- Joseph P. Vacca,
- Jules A. Shafer,
- and Joseph J. Lynch, Jr.
Antithrombotic Efficacy of Thrombin Inhibitor L-374,087: Intravenous Activity in a Primate Model of Venous Thrombus Extension and Oral Activity in a Canine Model of Primary Venous and Coronary Artery Thrombosis
J Pharmacol Exp Ther April 1, 1999 289:503-510
Select this article
- Laurence P. D. Bishop,
- James L. Maggs,
- Paul M. O’Neill,
- and B. Kevin Park
Metabolism of the Antimalarial Endoperoxide Ro 42-1611 (Arteflene) in the Rat: Evidence for Endoperoxide Bioactivation
J Pharmacol Exp Ther April 1, 1999 289:511-520
Select this article
- Cory M. Campbell,
- Eduardo R. Butelman,
- and James H. Woods
Effects of (+)-HA-966, CGS-19755, Phencyclidine, and Dizocilpine on Repeated Acquisition of Response Chains in Pigeons: Systemic Manipulation of Central Glycine Sites ,
J Pharmacol Exp Ther April 1, 1999 289:521-527
Select this article
- Helga E. de Vries,
- Anne C. E. Moor,
- Tom M.A.R. Dubbelman,
- Theo J. C. van Berkel,
- and Johan Kuiper
Oxidized Low-Density Lipoprotein as a Delivery System for Photosensitizers: Implications for Photodynamic Therapy of Atherosclerosis
J Pharmacol Exp Ther April 1, 1999 289:528-534
Select this article
- David W. Johnson,
- Heather J. Saunders,
- Fiona J. Johnson,
- Syed O. Huq,
- Michael J. Field,
- and Carol A. Pollock
Cyclosporin Exerts a Direct Fibrogenic Effect on Human Tubulointerstitial Cells: Roles of Insulin-Like Growth Factor I, Transforming Growth Factor β₁, and Platelet-Derived Growth Factor
J Pharmacol Exp Ther April 1, 1999 289:535-542
Select this article
- Joseph J. McArdle,
- Thomas L. Lentz,
- Veit Witzemann,
- Holger Schwarz,
- Scott A. Weinstein,
- and James J. Schmidt
Waglerin-1 Selectively Blocks the Epsilon Form of the Muscle Nicotinic Acetylcholine Receptor
J Pharmacol Exp Ther April 1, 1999 289:543-550
Select this article
- Murali Gopalakrishnan,
- Kristi L. Whiteaker,
- Eduardo J. Molinari,
- Rachel Davis-Taber,
- Victoria E. S. Scott,
- Char-Chang Shieh,
- Steve A. Buckner,
- Ivan Milicic,
- John C. Cain,
- Steve Postl,
- James P. Sullivan,
- and Jorge D. Brioni
Characterization of the ATP-Sensitive Potassium Channels (K_ATP) Expressed in Guinea Pig Bladder Smooth Muscle Cells
J Pharmacol Exp Ther April 1, 1999 289:551-558
Select this article
- A. Bergamo,
- R. Gagliardi,
- V. Scarcia,
- A. Furlani,
- E. Alessio,
- G. Mestroni,
- and G. Sava
In Vitro Cell Cycle Arrest, In Vivo Action on Solid Metastasizing Tumors, and Host Toxicity of the Antimetastatic Drug NAMI-A and Cisplatin
J Pharmacol Exp Ther April 1, 1999 289:559-564
Select this article
- Hans Peter Brunner-La Rocca,
- Daniel Weilenmann,
- Wolfgang Kiowski,
- Friedrich E. Maly,
- and Ferenc Follath
Plasma Levels of Enalaprilat in Chronic Therapy of Heart Failure: Relationship to Adverse Events
J Pharmacol Exp Ther April 1, 1999 289:565-571
Select this article
- Jae W. Choi and
- Sung E. Jung
Lovastatin-Induced Proliferation Inhibition and Apoptosis in C6 Glial Cells
J Pharmacol Exp Ther April 1, 1999 289:572-579
Select this article
- Jie Liu,
- Yaping Liu,
- Dylan Hartley,
- Curtis D. Klaassen,
- Stacey E. Shehin-Johnson,
- Angela Lucas,
- and Steven D. Cohen
Metallothionein-I/II Knockout Mice Are Sensitive to Acetaminophen-Induced Hepatotoxicity
J Pharmacol Exp Ther April 1, 1999 289:580-586
Select this article
- Eugenia V. Gurevich,
- J. William Himes,
- and Jeffrey N. Joyce
Developmental Regulation of Expression of the D₃Dopamine Receptor in Rat Nucleus Accumbens and Islands of Calleja
J Pharmacol Exp Ther April 1, 1999 289:587-598
Select this article
- Rüdiger Schulz,
- Andrea Wehmeyer,
- Karin Schulz,
- and John Murphy
Effect of Phosducin on Opioid Receptor Function
J Pharmacol Exp Ther April 1, 1999 289:599-606

Current Issue

November 2009, 331 (2)

Articles

Stable Incorporation of a Lipophilic Daunorubicin Prodrug into Apolipoprotein E-Exposing Liposomes Induces Uptake of Prodrug via Low-Density Lipoprotein Receptor in Vivo

Response Surface Analysis of Synergism Between Morphine and Clonidine

Comparison of Effects of Haloperidol Administration on Amphetamine-Stimulated Dopamine Release in the Rat Medial Prefrontal Cortex and Dorsal Striatum

Glucocorticoid Enhances Interleukin-1-Induced Pressor Response in Freely Moving Rats Through Its Effect on Nitric Oxide Release

In Vitro Metabolism of Quinidine: The (3S)-3-Hydroxylation of Quinidine Is a Specific Marker Reaction for Cytochrome P-4503A4 Activity in Human Liver Microsomes

Necessary Role for Ventral Tegmental Area Adenylate Cyclase and Protein Kinase A in Induction of Behavioral Sensitization to Intraventral Tegmental Area Amphetamine

In Vitro and In Vivo Characterization of Intrinsic Sympathomimetic Activity in Normal and Heart Failure Rats

Female Gonadal Hormones Differentially Modulate Cocaine-Induced Behavioral Sensitization in Fischer, Lewis, and Sprague-Dawley Rats

Multiplicity of the H+-Dependent Transport Mechanism of Dipeptide and Anionic β-Lactam Antibiotic Ceftibuten in Rat Intestinal Brush-Border Membrane

Anti-Herpes Simplex Virus Activity of Moronic Acid Purified fromRhus javanica In Vitro and In Vivo

Carrier-Mediated Lung Distribution of HSR-903, a New Quinolone Antibacterial Agent

Effects of LY295427, a Low-Density Lipoprotein (LDL) Receptor Up-Regulator, on LDL Receptor Gene Transcription and Cholesterol Metabolism in Normal and Hypercholesterolemic Hamsters

Pharmacokinetic Analysis of the Cardioprotective Effect of 3-(2,2,2-Trimethylhydrazinium) Propionate in Mice: Inhibition of Carnitine Transport in Kidney

Role of Antioxidant Defenses Against Ethanol-Induced Damage in Cultured Rat Gastric Epithelial Cells

Behavioral and Neurochemical Effects of the Dopamine Transporter Ligand 4-Chlorobenztropine Alone and in Combination with Cocaine In Vivo

Tretinoin Prevents Age-Related Renal Changes and Stimulates Antioxidant Defenses in Cultured Renal Mesangial Cells

Local α-Bungarotoxin-Sensitive Nicotinic Receptors Modulate Hippocampal Norepinephrine Release by Systemic Nicotine

Prostaglandin E-Prostanoid-3 Receptor Activation of Cyclic AMP Response Element-Mediated Gene Transcription

Transport of Rhodamine 123, a P-Glycoprotein Substrate, across Rat Intestine and Caco-2 Cell Monolayers in the Presence of Cytochrome P-450 3A-Related Compounds

Electrophysiologic Effects of Chronic Amiodarone Therapy and Hypothyroidism, Alone and in Combination, on Guinea Pig Ventricular Myocytes

Effects of Petrosaspongiolide M, a Novel Phospholipase A2 Inhibitor, on Acute and Chronic Inflammation

Central Administration of [Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)-NH2and Orphanin FQ/Nociceptin (OFQ/N) Produce Similar Cardiovascular and Renal Responses in Conscious Rats

Effects of Bay 10–6734 (Embusartan), a New Angiotensin II Type I Receptor Antagonist, on Vascular Smooth Muscle Cell Growth ,

Pharmacological Characterization of Protein Phosphatase Activities in Preparations from Failing Human Hearts

Comparison of Two Aquaretic Drugs (Niravoline and OPC-31260) in Cirrhotic Rats with Ascites and Water Retention

Both the Antioxidant and D3 Agonist Actions of Pramipexole Mediate Its Neuroprotective Actions in Mesencephalic Cultures

Effects of Pirfenidone on Procollagen Gene Expression at the Transcriptional Level in Bleomycin Hamster Model of Lung Fibrosis

Orexin A but Not Orexin B Rapidly Enters Brain from Blood by Simple Diffusion

Decreased Tissue Distribution of l-Carnitine in Juvenile Visceral Steatosis Mice

Relationship Between Circadian Rhythm of Vinorelbine Toxicity and Efficacy in P388-Bearing Mice

RSD1000: A Novel Antiarrhythmic Agent with Increased Potency under Acidic and High-Potassium Conditions

A Role for N-Arachidonylethanolamine (Anandamide) as the Mediator of Sensory Nerve-Dependent Ca2+-Induced Relaxation

Molecular and Ligand-Binding Characterization of the ς-Receptor in the Jurkat Human T Lymphocyte Cell Line

Human Endothelin-1 Clearance Kinetics Revealed by a Radiotracer Technique

In Vivo Dopamine Clearance Rate in Rat Striatum: Regulation by Extracellular Dopamine Concentration and Dopamine Transporter Inhibitors

Modulation of Amphetamine-Stimulated [3H]Dopamine Release from Rat Pheochromocytoma (PC12) Cells by ς Type 2 Receptors

Caffeine Withdrawal: A Parametric Analysis of Caffeine Dosing Conditions

Interaction Between Neutral Endopeptidase and Angiotensin Converting Enzyme Inhibition in Rats with Myocardial Infarction: Effects on Cardiac Hypertrophy and Angiotensin and Bradykinin Peptide Levels

Nitrocinnamoyl and Chlorocinnamoyl Derivatives of Dihydrocodeinone: In Vivo and In Vitro Characterization of μ-Selective Agonist and Antagonist Activity

κ- and μ-Opioid Inhibition of N-Type Calcium Currents Is Attenuated by 4β-Phorbol 12-Myristate 13-Acetate and Protein Kinase C in Rat Dorsal Root Ganglion Neurons

A-Current Down-Modulated by ς Receptor in Frog Pituitary Melanotrope Cells Through a G Protein-Dependent Pathway

Comparative Pharmacokinetics of Vinblastine after a 96-Hour Continuous Infusion in Wild-Type Mice and Mice Lacking mdr1a P-Glycoprotein

Modeling Geriatric Depression in Animals: Biochemical and Behavioral Effects of Olfactory Bulbectomy in Young Versus Aged Rats

Cimetidine Transport in Brush-Border Membrane Vesicles from Rat Small Intestine

Precontraction with Elevated Concentrations of Extracellular Potassium Enables both 5-HT1B and 5-HT2A“Silent” Receptors in Rabbit Ear Artery

Formate-Induced Inhibition of Photoreceptor Function in Methanol Intoxication

Down-Regulation Models and Modeling of Testosterone Production Induced by Recombinant Human Choriogonadotropin

Activation of Peripheral κ Opioid Receptors Inhibits Capsaicin-Induced Thermal Nociception in Rhesus Monkeys

Fatty Acid Block of the Transient Outward Current in Adult Human Atrium

Synergistic Interactions between Ampakines and Antipsychotic Drugs

Nitric Oxide Is the Predominant Mediator for Neurogenic Vasodilation in Porcine Pial Veins

Ethanol-Like Discriminative Stimulus Effects of Endogenous Neuroactive Steroids: Effect of Ethanol Training Dose and Dosing Procedure

The Regulation of Dopamine Transmission by Metabotropic Glutamate Receptors

Antinociceptive Properties of the New Alkaloid,cis-8,10-Di-N-Propyllobelidiol Hydrochloride Dihydrate Isolated from Siphocampylus verticillatus: Evidence for the Mechanism of Action

S-16924, a Novel, Potential Antipsychotic with Marked Serotonin1A Agonist Properties. IV. A Drug Discrimination Comparison with Clozapine

A New CYP2A6 Gene Deletion Responsible for the In Vivo Polymorphic Metabolism of (+)-cis-3,5-Dimethyl-2-(3-pyridyl)thiazolidin-4-one Hydrochloride in Humans

Chronic Lithium Treatment Inhibits Amiloride-Sensitive Sodium Transport in the Rat Distal Nephron

Interactions of a Nonpeptidic Drug, Valacyclovir, with the Human Intestinal Peptide Transporter (hPEPT1) Expressed in a Mammalian Cell Line

Differences in Pharmacological Properties of Dopamine Release Between the Substantia Nigra and Striatum: An In Vivo Electrochemical Study

Muscarinic M3 Receptor Inactivation Reveals a Pertussis Toxin-Sensitive Contractile Response in the Guinea Pig Colon: Evidence for M2/M3 Receptor Interactions

Mechanisms of δ-Hexachlorocyclohexane Toxicity: I. Relationship Between Altered Ventricular Myocyte Contractility and Ryanodine Receptor Function

Mechanisms of δ-Hexachlorocyclohexane Toxicity: II. Evidence for Ca2+-Dependent K+-Selective Ionophore Activity

Loperamide (ADL 2-1294), an Opioid Antihyperalgesic Agent with Peripheral Selectivity

Antithrombotic Efficacy of Thrombin Inhibitor L-374,087: Intravenous Activity in a Primate Model of Venous Thrombus Extension and Oral Activity in a Canine Model of Primary Venous and Coronary Artery Thrombosis

Metabolism of the Antimalarial Endoperoxide Ro 42-1611 (Arteflene) in the Rat: Evidence for Endoperoxide Bioactivation

Effects of (+)-HA-966, CGS-19755, Phencyclidine, and Dizocilpine on Repeated Acquisition of Response Chains in Pigeons: Systemic Manipulation of Central Glycine Sites ,

Oxidized Low-Density Lipoprotein as a Delivery System for Photosensitizers: Implications for Photodynamic Therapy of Atherosclerosis

Cyclosporin Exerts a Direct Fibrogenic Effect on Human Tubulointerstitial Cells: Roles of Insulin-Like Growth Factor I, Transforming Growth Factor β1, and Platelet-Derived Growth Factor

Waglerin-1 Selectively Blocks the Epsilon Form of the Muscle Nicotinic Acetylcholine Receptor

Characterization of the ATP-Sensitive Potassium Channels (KATP) Expressed in Guinea Pig Bladder Smooth Muscle Cells

In Vitro Cell Cycle Arrest, In Vivo Action on Solid Metastasizing Tumors, and Host Toxicity of the Antimetastatic Drug NAMI-A and Cisplatin

Plasma Levels of Enalaprilat in Chronic Therapy of Heart Failure: Relationship to Adverse Events

Lovastatin-Induced Proliferation Inhibition and Apoptosis in C6 Glial Cells

Metallothionein-I/II Knockout Mice Are Sensitive to Acetaminophen-Induced Hepatotoxicity

Developmental Regulation of Expression of the D3Dopamine Receptor in Rat Nucleus Accumbens and Islands of Calleja

Effect of Phosducin on Opioid Receptor Function

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Multiplicity of the H⁺-Dependent Transport Mechanism of Dipeptide and Anionic β-Lactam Antibiotic Ceftibuten in Rat Intestinal Brush-Border Membrane

Effects of Petrosaspongiolide M, a Novel Phospholipase A₂ Inhibitor, on Acute and Chronic Inflammation

Central Administration of [Phe¹Ψ(CH₂-NH)Gly²]Nociceptin(1-13)-NH₂and Orphanin FQ/Nociceptin (OFQ/N) Produce Similar Cardiovascular and Renal Responses in Conscious Rats

Both the Antioxidant and D₃ Agonist Actions of Pramipexole Mediate Its Neuroprotective Actions in Mesencephalic Cultures

A Role for N-Arachidonylethanolamine (Anandamide) as the Mediator of Sensory Nerve-Dependent Ca²⁺-Induced Relaxation

Modulation of Amphetamine-Stimulated [³H]Dopamine Release from Rat Pheochromocytoma (PC12) Cells by ς Type 2 Receptors

Precontraction with Elevated Concentrations of Extracellular Potassium Enables both 5-HT_1B and 5-HT_2A“Silent” Receptors in Rabbit Ear Artery

S-16924, a Novel, Potential Antipsychotic with Marked Serotonin_1A Agonist Properties. IV. A Drug Discrimination Comparison with Clozapine

Muscarinic M₃ Receptor Inactivation Reveals a Pertussis Toxin-Sensitive Contractile Response in the Guinea Pig Colon: Evidence for M₂/M₃ Receptor Interactions

Mechanisms of δ-Hexachlorocyclohexane Toxicity: II. Evidence for Ca²⁺-Dependent K⁺-Selective Ionophore Activity

Cyclosporin Exerts a Direct Fibrogenic Effect on Human Tubulointerstitial Cells: Roles of Insulin-Like Growth Factor I, Transforming Growth Factor β₁, and Platelet-Derived Growth Factor

Characterization of the ATP-Sensitive Potassium Channels (K_ATP) Expressed in Guinea Pig Bladder Smooth Muscle Cells

Developmental Regulation of Expression of the D₃Dopamine Receptor in Rat Nucleus Accumbens and Islands of Calleja