Table of Contents

March 1999; 288 (3)

Articles

Select this article
- Linda P. Dwoskin,
- Lihong Teng,
- Susan T. Buxton,
- and Peter A. Crooks
(S)-(−)-Cotinine, the Major Brain Metabolite of Nicotine, Stimulates Nicotinic Receptors to Evoke [³H]Dopamine Release from Rat Striatal Slices in a Calcium-Dependent Manner
J Pharmacol Exp Ther March 1, 1999 288:905-911
Select this article
- Hideo Tanaka and
- Kenji Mizojiri
Drug-Protein Binding and Blood-Brain Barrier Permeability
J Pharmacol Exp Ther March 1, 1999 288:912-918
Select this article
- Eiichiro Hatta,
- Ryushi Maruyama,
- Stuart J. Marshall,
- Michiaki Imamura,
- and Roberto Levi
Bradykinin Promotes Ischemic Norepinephrine Release in Guinea Pig and Human Hearts
J Pharmacol Exp Ther March 1, 1999 288:919-927
Select this article
- Li J. Yu,
- Pernille Drewes,
- Katja Gustafsson,
- Etienne G. C. Brain,
- Jodi E. D. Hecht,
- and David J. Waxman
In Vivo Modulation of Alternative Pathways of P-450-Catalyzed Cyclophosphamide Metabolism: Impact on Pharmacokinetics and Antitumor Activity
J Pharmacol Exp Ther March 1, 1999 288:928-937
Select this article
- Guang-Wu Wang and
- Y. James Kang
Inhibition of Doxorubicin Toxicity in Cultured Neonatal Mouse Cardiomyocytes with Elevated Metallothionein Levels
J Pharmacol Exp Ther March 1, 1999 288:938-944
Select this article
- Graham W. Warren,
- Samuel M. Poloyac,
- Devin S. Gary,
- Mark P. Mattson,
- and Robert A. Blouin
Hepatic Cytochrome P-450 Expression in Tumor Necrosis Factor-α Receptor (p55/p75) Knockout Mice After Endotoxin Administration
J Pharmacol Exp Ther March 1, 1999 288:945-950
Select this article
- Timothy P. Reilly,
- Patrick M. Woster,
- and Craig K. Svensson
Methemoglobin Formation by Hydroxylamine Metabolites of Sulfamethoxazole and Dapsone: Implications for Differences in Adverse Drug Reactions
J Pharmacol Exp Ther March 1, 1999 288:951-959
Select this article
- S. Taverna,
- G. Sancini,
- M. Mantegazza,
- S. Franceschetti,
- and G. Avanzini
Inhibition of Transient and Persistent Na⁺ Current Fractions by the New Anticonvulsant Topiramate
J Pharmacol Exp Ther March 1, 1999 288:960-968
Select this article
- Rennolds S. Ostrom and
- Frederick J. Ehlert
Comparison of Functional Antagonism Between Isoproterenol and M₂ Muscarinic Receptors in Guinea Pig Ileum and Trachea
J Pharmacol Exp Ther March 1, 1999 288:969-976
Select this article
- Xiang-Qun Hu,
- Shumei Yang,
- William J. Pearce,
- Lawrence D. Longo,
- and Lubo Zhang
Effect of Chronic Hypoxia on Alpha-1 Adrenoceptor-Mediated Inositol 1,4,5-Trisphosphate Signaling in Ovine Uterine Artery
J Pharmacol Exp Ther March 1, 1999 288:977-983
Select this article
- Wolfgang Löscher,
- Holger Lehmann,
- Hans-Jürgen Teschendorf,
- Martin Traut,
- and Gerhard Gross
Inhibition of Monoamine Oxidase Type A, but Not Type B, Is an Effective Means of Inducing Anticonvulsant Activity in the Kindling Model of Epilepsy
J Pharmacol Exp Ther March 1, 1999 288:984-992
Select this article
- Varanuj Chatsudthipong,
- Promsuk Jutabha,
- Kristen K. Evans,
- and William H. Dantzler
Effects of Inhibitors and Substitutes for Chloride in Lumen onp-Aminohippurate Transport by Isolated Perfused Rabbit Renal Proximal Tubules
J Pharmacol Exp Ther March 1, 1999 288:993-1001
Select this article
- Mark J. Millan,
- Mauricette Brocco,
- Alain Gobert,
- Rudy Schreiber,
- and Anne Dekeyne
S-16924 [(R)-2-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl}-1-(4-fluorophenyl)-ethanone], a Novel, Potential Antipsychotic with Marked Serotonin_1AAgonist Properties: III. Anxiolytic Actions in Comparison with Clozapine and Haloperidol
J Pharmacol Exp Ther March 1, 1999 288:1002-1014
Select this article
- Yukun Yuan and
- William D. Atchison
Comparative Effects of Methylmercury on Parallel-Fiber and Climbing-Fiber Responses of Rat Cerebellar Slices
J Pharmacol Exp Ther March 1, 1999 288:1015-1025
Select this article
- Hui-Lin Pan,
- James C. Eisenach,
- and Shao-Rui Chen
Gabapentin Suppresses Ectopic Nerve Discharges and Reverses Allodynia in Neuropathic Rats
J Pharmacol Exp Ther March 1, 1999 288:1026-1030
Select this article
- Tomio Okamura,
- Kazuhide Ayajiki,
- Masami Uchiyama,
- Masami Uehara,
- and Noboru Toda
Neurogenic Vasodilatation of Canine Isolated Small Labial Arteries
J Pharmacol Exp Ther March 1, 1999 288:1031-1036
Select this article
- Françoise Berlioz,
- Stéphanie Julien,
- Annick Tsocas,
- Jacques Chariot,
- Claude Carbon,
- Robert Farinotti,
- and Claude Rozé
Neural Modulation of Cephalexin Intestinal Absorption Through the Di- and Tripeptide Brush Border Transporter of Rat Jejunum In Vivo
J Pharmacol Exp Ther March 1, 1999 288:1037-1044
Select this article
- Francesca Crema,
- Chiara Modini,
- Tiziano Croci,
- Michel Langlois,
- and Fabrizio de Ponti
Intestinal Prokinesia by Two Esters of 4-Amino-5-Chloro-2-Methoxybenzoic Acid: Involvement of 5-Hydroxytryptamine-4 Receptors and Dissociation from Cardiac Effects In Vivo
J Pharmacol Exp Ther March 1, 1999 288:1045-1052
Select this article
- Maciej Gasior,
- Mohammed Shoaib,
- Sevil Yasar,
- Maria Jaszyna,
- and Steven R. Goldberg
Acquisition of Nicotine Discrimination and Discriminative Stimulus Effects of Nicotine in Rats Chronically Exposed to Caffeine ,
J Pharmacol Exp Ther March 1, 1999 288:1053-1073
Select this article
- P. Ferrari,
- M. Ferrandi,
- G. Tripodi,
- L. Torielli,
- G. Padoani,
- E. Minotti,
- P. Melloni,
- and G. Bianchi
PST 2238: A New Antihypertensive Compound that Modulates Na,K-ATPase in Genetic Hypertension
J Pharmacol Exp Ther March 1, 1999 288:1074-1083
Select this article
- Andrea Teschemacher and
- Horst Lemoine
Kinetic Analysis of Drug-Receptor Interactions of Long-Acting β₂ Sympathomimetics in Isolated Receptor Membranes: Evidence against Prolonged Effects of Salmeterol and Formoterol on Receptor-Coupled Adenylyl Cyclase
J Pharmacol Exp Ther March 1, 1999 288:1084-1092
Select this article
- Lilijana Šprah,
- Marko Živin,
- and Dušan Sket
Ergoline Derivative LEK-8829-Induced Turning Behavior in Rats with Unilateral Striatal Ibotenic Acid Lesions: Interaction with Bromocriptine
J Pharmacol Exp Ther March 1, 1999 288:1093-1100
Select this article
- Michael A. Saunders,
- Maria G. Belvisi,
- Guiseppe Cirino,
- P. J. Barnes,
- Timothy D. Warner,
- and Jane A. Mitchell
Mechanisms of Prostaglandin E₂ Release by Intact Cells Expressing Cyclooxygenase-2: Evidence for a ‘Two-Component’ Model
J Pharmacol Exp Ther March 1, 1999 288:1101-1106
Select this article
- Carolyn A. Fairbanks and
- George L. Wilcox
Spinal Antinociceptive Synergism between Morphine and Clonidine Persists in Mice Made Acutely or Chronically Tolerant to Morphine
J Pharmacol Exp Ther March 1, 1999 288:1107-1116
Select this article
- David W. Snyder,
- Nicholas J. Bach,
- Robert D. Dillard,
- Susan E. Draheim,
- Donald G. Carlson,
- Niles Fox,
- Neal W. Roehm,
- Christopher T. Armstrong,
- Chan H. Chang,
- Lawrence W. Hartley,
- Lea M. Johnson,
- Carlos R. Roman,
- Amy C. Smith,
- Min Song,
- and Jerome H. Fleisch
Pharmacology of LY315920/S-5920,[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A₂Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI
J Pharmacol Exp Ther March 1, 1999 288:1117-1124
Select this article
- S. F. de Boer,
- M. Lesourd,
- E. Mocaer,
- and J. M. Koolhaas
Selective Antiaggressive Effects of Alnespirone in Resident-Intruder Test Are Mediated via 5-Hydroxytryptamine_1A Receptors: A Comparative Pharmacological Study with 8-Hydroxy-2-Dipropylaminotetralin, Ipsapirone, Buspirone, Eltoprazine, and WAY-100635
J Pharmacol Exp Ther March 1, 1999 288:1125-1133
Select this article
- H. Kevin Happe,
- David B. Bylund,
- and L. Charles Murrin
Alpha-2 Adrenergic Receptor Functional Coupling to G Proteins in Rat Brain During Postnatal Development
J Pharmacol Exp Ther March 1, 1999 288:1134-1142
Select this article
- James L. Ellis,
- Dean Harman,
- Javier Gonzalez,
- Michael L. Spera,
- Ronggang Liu,
- T. Y. Shen,
- Donna M. Wypij,
- and Fangming Zuo
Development of Muscarinic Analgesics Derived from Epibatidine: Role of the M₄ Receptor Subtype
J Pharmacol Exp Ther March 1, 1999 288:1143-1150
Select this article
- P. Salvati,
- R. Maj,
- C. Caccia,
- M. A. Cervini,
- M. G. Fornaretto,
- E. Lamberti,
- P. Pevarello,
- G. A. Skeen,
- H. S. White,
- H. H. Wolf,
- L. Faravelli,
- M. Mazzanti,
- E. Mancinelli,
- M. Varasi,
- and R. G. Fariello
Biochemical and Electrophysiological Studies on the Mechanism of Action of PNU-151774E, A Novel Antiepileptic Compound
J Pharmacol Exp Ther March 1, 1999 288:1151-1159
Select this article
- Scot C. Westwood and
- Glen R. Hanson
Effects of Stimulants of Abuse on Extrapyramidal and Limbic Neuropeptide Y Systems
J Pharmacol Exp Ther March 1, 1999 288:1160-1166
Select this article
- Minako Kaburaki,
- Hideo Yabana,
- Hisayoshi Doi,
- Koichi Nagata,
- Hiroshi Narita,
- and Sakae Murata
The Mechanism of the Increasing Action of TA-993, a New 1,5-Benzothiazepine Derivative, on Limb Blood Flow in Anesthetized Dogs: Selective Suppression of Sympathetic Nerve Activity
J Pharmacol Exp Ther March 1, 1999 288:1167-1173
Select this article
- Bengt Särnstrand,
- Anne-Helene Jansson,
- Giedre Matuseviciene,
- Annika Scheynius,
- Stefan Pierrou,
- and Håkan Bergstrand
N,N′-Diacetyl-l-cystine—the Disulfide Dimer of N-acetylcysteine—Is a Potent Modulator of Contact Sensitivity/Delayed Type Hypersensitivity Reactions in Rodents
J Pharmacol Exp Ther March 1, 1999 288:1174-1184
Select this article
- James R. Hammond,
- Stephanie Lee,
- and Peter J. Ferguson
[³H]Gemcitabine Uptake by Nucleoside Transporters in a Human Head and Neck Squamous Carcinoma Cell Line
J Pharmacol Exp Ther March 1, 1999 288:1185-1191
Select this article
- Lei Zhang,
- Wenche Gorset,
- Mark J. Dresser,
- and Kathleen M. Giacomini
The Interaction of n-Tetraalkylammonium Compounds with a Human Organic Cation Transporter, hOCT1
J Pharmacol Exp Ther March 1, 1999 288:1192-1198
Select this article
- C. Fernando Valenzuela and
- Rita A. Cardoso
Acute Effects of Ethanol on Kainate Receptors with Different Subunit Compositions
J Pharmacol Exp Ther March 1, 1999 288:1199-1206
Select this article
- Pierre Gressens,
- Leslie Besse,
- Patrick Robberecht,
- Illana Gozes,
- Mati Fridkin,
- and Philippe Evrard
Neuroprotection of the Developing Brain by Systemic Administration of Vasoactive Intestinal Peptide Derivatives
J Pharmacol Exp Ther March 1, 1999 288:1207-1213
Select this article
- Katsuya Onishi,
- Michiya Ohno,
- William C. Little,
- and Che-Ping Cheng
Endogenous Endothelin-1 Depresses Left Ventricular Systolic and Diastolic Performance in Congestive Heart Failure
J Pharmacol Exp Ther March 1, 1999 288:1214-1222
Select this article
- Amanda D. Smith and
- Friedbert Weiss
Ethanol Exposure Differentially Alters Central Monoamine Neurotransmission in Alcohol-Preferring versus -Nonpreferring Rats
J Pharmacol Exp Ther March 1, 1999 288:1223-1228
Select this article
- Tomoo Inoue,
- Zaichuan Mi,
- Delbert G. Gillespie,
- Raghvendra K. Dubey,
- and Edwin K. Jackson
Angiotensin Receptor Subtype 1 Mediates Angiotensin II Enhancement of Isoproterenol-Induced Cyclic AMP Production in Preglomerular Microvascular Smooth Muscle Cells
J Pharmacol Exp Ther March 1, 1999 288:1229-1234
Select this article
- Nuria A. Callejas,
- Antonio Castrillo,
- Lisardo Boscá,
- and Paloma Martı́n-Sanz
Inhibition of Prostaglandin Synthesis Up-Regulates Cyclooxygenase-2 Induced by Lipopolysaccharide and Peroxisomal Proliferators
J Pharmacol Exp Ther March 1, 1999 288:1235-1241
Select this article
- Kenichi Kato,
- A. Mark Evans,
- and Roland Z. Kozlowski
Relaxation of Endothelin-1-Induced Pulmonary Arterial Constriction by Niflumic Acid and NPPB: Mechanism(s) Independent of Chloride Channel Block
J Pharmacol Exp Ther March 1, 1999 288:1242-1250
Select this article
- John R. Cashman,
- Yeng N. Xiong,
- Lifen Xu,
- and Aaron Janowsky
N-Oxygenation of Amphetamine and Methamphetamine by the Human Flavin-Containing Monooxygenase (Form 3): Role in Bioactivation and Detoxication
J Pharmacol Exp Ther March 1, 1999 288:1251-1260
Select this article
- Benoit Drolet,
- Frédérick Vincent,
- Jimmy Rail,
- Mohamed Chahine,
- Dominic Deschênes,
- Sylvie Nadeau,
- Majed Khalifa,
- Bettina A. Hamelin,
- and Jacques Turgeon
Thioridazine Lengthens Repolarization of Cardiac Ventricular Myocytes by Blocking the Delayed Rectifier Potassium Current
J Pharmacol Exp Ther March 1, 1999 288:1261-1268
Select this article
- Keith W. Easterling and
- Stephen G. Holtzman
Discriminative Stimulus Effects of Naltrexone After a Single Dose of Morphine in the Rat
J Pharmacol Exp Ther March 1, 1999 288:1269-1277
Select this article
- Wilfred Lieberthal,
- Robert Fuhro,
- Jane E. Freedman,
- George Toolan,
- Joseph Loscalzo,
- and C. Robert Valeri
O-Raffinose Cross-Linking Markedly Reduces Systemic and Renal Vasoconstrictor Effects of Unmodified Human Hemoglobin
J Pharmacol Exp Ther March 1, 1999 288:1278-1287
Select this article
- Mary-Frances Jett,
- Chakk S. Ramesha,
- Carl D. Brown,
- Sophie Chiu,
- Caroline Emmett,
- Tatyana Voronin,
- Thomas Sun,
- Counde O’Yang,
- John C. Hunter,
- Richard M. Eglen,
- and Randolph M. Johnson
Characterization of the Analgesic and Anti-Inflammatory Activities of Ketorolac and Its Enantiomers in the Rat
J Pharmacol Exp Ther March 1, 1999 288:1288-1297
Select this article
- J. M. Witkin,
- N. Savtchenko,
- M. Mashkovsky,
- M. Beekman,
- P. Munzar,
- M. Gasior,
- S. R. Goldberg,
- J. T. Ungard,
- J. Kim,
- T. Shippenberg,
- and V. Chefer
Behavioral, Toxic, and Neurochemical Effects of Sydnocarb, a Novel Psychomotor Stimulant: Comparisons with Methamphetamine
J Pharmacol Exp Ther March 1, 1999 288:1298-1310
Select this article
- Deanne L. Heath and
- Robert Vink
Optimization of Magnesium Therapy after Severe Diffuse Axonal Brain Injury in Rats
J Pharmacol Exp Ther March 1, 1999 288:1311-1316
Select this article
- Geri A. Sawada,
- Craig L. Barsuhn,
- Barry S. Lutzke,
- Michael E. Houghton,
- Guy E. Padbury,
- Norman F. H. Ho,
- and Thomas J. Raub
Increased Lipophilicity and Subsequent Cell Partitioning Decrease Passive Transcellular Diffusion of Novel, Highly Lipophilic Antioxidants
J Pharmacol Exp Ther March 1, 1999 288:1317-1326
Select this article
- Geri A. Sawada,
- Lawrence R. Williams,
- Barry S. Lutzke,
- and Thomas J. Raub
Novel, Highly Lipophilic Antioxidants Readily Diffuse Across the Blood-Brain Barrier and Access Intracellular Sites
J Pharmacol Exp Ther March 1, 1999 288:1327-1333
Select this article
- Meleik A. Hebert,
- Gaynor A. Larson,
- Nancy R. Zahniser,
- and Greg A. Gerhardt
Age-Related Reductions in [³H]WIN 35,428 Binding to the Dopamine Transporter in Nigrostriatal and Mesolimbic Brain Regions of the Fischer 344 Rat
J Pharmacol Exp Ther March 1, 1999 288:1334-1339
Select this article
- Anumantha G. Kanthasamy,
- Richard J. Yun,
- Bang Nguyen,
- and Daniel D. Truong
Effect of Riluzole on the Neurological and Neuropathological Changes in an Animal Model of Cardiac Arrest-Induced Movement Disorder
J Pharmacol Exp Ther March 1, 1999 288:1340-1348
Select this article
- Leena K. Singh,
- William Boucher,
- Xinzhu Pang,
- Richard Letourneau,
- Dimitri Seretakis,
- Marlon Green,
- and Theoharis C. Theoharides
Potent Mast Cell Degranulation and Vascular Permeability Triggered by Urocortin Through Activation of Corticotropin-Releasing Hormone Receptors
J Pharmacol Exp Ther March 1, 1999 288:1349-1356
Select this article
- Yaakov Waksman,
- John M. Olson,
- Steven J. Carlisle,
- and Guy A. Cabral
The Central Cannabinoid Receptor (CB1) Mediates Inhibition of Nitric Oxide Production by Rat Microglial Cells
J Pharmacol Exp Ther March 1, 1999 288:1357-1366
Select this article
- Masayuki Takeda,
- Kenji Obara,
- Takaki Mizusawa,
- Yoshihiko Tomita,
- Kei Arai,
- Toshiki Tsutsui,
- Akihiko Hatano,
- Kota Takahashi,
- and Shintaro Nomura
Evidence for β₃-Adrenoceptor Subtypes in Relaxation of the Human Urinary Bladder Detrusor: Analysis by Molecular Biological and Pharmacological Methods
J Pharmacol Exp Ther March 1, 1999 288:1367-1373

Current Issue

November 2009, 331 (2)

Articles

(S)-(−)-Cotinine, the Major Brain Metabolite of Nicotine, Stimulates Nicotinic Receptors to Evoke [3H]Dopamine Release from Rat Striatal Slices in a Calcium-Dependent Manner

Drug-Protein Binding and Blood-Brain Barrier Permeability

Bradykinin Promotes Ischemic Norepinephrine Release in Guinea Pig and Human Hearts

In Vivo Modulation of Alternative Pathways of P-450-Catalyzed Cyclophosphamide Metabolism: Impact on Pharmacokinetics and Antitumor Activity

Inhibition of Doxorubicin Toxicity in Cultured Neonatal Mouse Cardiomyocytes with Elevated Metallothionein Levels

Hepatic Cytochrome P-450 Expression in Tumor Necrosis Factor-α Receptor (p55/p75) Knockout Mice After Endotoxin Administration

Methemoglobin Formation by Hydroxylamine Metabolites of Sulfamethoxazole and Dapsone: Implications for Differences in Adverse Drug Reactions

Inhibition of Transient and Persistent Na+ Current Fractions by the New Anticonvulsant Topiramate

Comparison of Functional Antagonism Between Isoproterenol and M2 Muscarinic Receptors in Guinea Pig Ileum and Trachea

Effect of Chronic Hypoxia on Alpha-1 Adrenoceptor-Mediated Inositol 1,4,5-Trisphosphate Signaling in Ovine Uterine Artery

Inhibition of Monoamine Oxidase Type A, but Not Type B, Is an Effective Means of Inducing Anticonvulsant Activity in the Kindling Model of Epilepsy

Effects of Inhibitors and Substitutes for Chloride in Lumen onp-Aminohippurate Transport by Isolated Perfused Rabbit Renal Proximal Tubules

S-16924 [(R)-2-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl}-1-(4-fluorophenyl)-ethanone], a Novel, Potential Antipsychotic with Marked Serotonin1AAgonist Properties: III. Anxiolytic Actions in Comparison with Clozapine and Haloperidol

Comparative Effects of Methylmercury on Parallel-Fiber and Climbing-Fiber Responses of Rat Cerebellar Slices

Gabapentin Suppresses Ectopic Nerve Discharges and Reverses Allodynia in Neuropathic Rats

Neurogenic Vasodilatation of Canine Isolated Small Labial Arteries

Neural Modulation of Cephalexin Intestinal Absorption Through the Di- and Tripeptide Brush Border Transporter of Rat Jejunum In Vivo

Intestinal Prokinesia by Two Esters of 4-Amino-5-Chloro-2-Methoxybenzoic Acid: Involvement of 5-Hydroxytryptamine-4 Receptors and Dissociation from Cardiac Effects In Vivo

Acquisition of Nicotine Discrimination and Discriminative Stimulus Effects of Nicotine in Rats Chronically Exposed to Caffeine ,

PST 2238: A New Antihypertensive Compound that Modulates Na,K-ATPase in Genetic Hypertension

Kinetic Analysis of Drug-Receptor Interactions of Long-Acting β2 Sympathomimetics in Isolated Receptor Membranes: Evidence against Prolonged Effects of Salmeterol and Formoterol on Receptor-Coupled Adenylyl Cyclase

Ergoline Derivative LEK-8829-Induced Turning Behavior in Rats with Unilateral Striatal Ibotenic Acid Lesions: Interaction with Bromocriptine

Mechanisms of Prostaglandin E2 Release by Intact Cells Expressing Cyclooxygenase-2: Evidence for a ‘Two-Component’ Model

Spinal Antinociceptive Synergism between Morphine and Clonidine Persists in Mice Made Acutely or Chronically Tolerant to Morphine

Pharmacology of LY315920/S-5920,[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A2Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI

Selective Antiaggressive Effects of Alnespirone in Resident-Intruder Test Are Mediated via 5-Hydroxytryptamine1A Receptors: A Comparative Pharmacological Study with 8-Hydroxy-2-Dipropylaminotetralin, Ipsapirone, Buspirone, Eltoprazine, and WAY-100635

Alpha-2 Adrenergic Receptor Functional Coupling to G Proteins in Rat Brain During Postnatal Development

Development of Muscarinic Analgesics Derived from Epibatidine: Role of the M4 Receptor Subtype

Biochemical and Electrophysiological Studies on the Mechanism of Action of PNU-151774E, A Novel Antiepileptic Compound

Effects of Stimulants of Abuse on Extrapyramidal and Limbic Neuropeptide Y Systems

The Mechanism of the Increasing Action of TA-993, a New 1,5-Benzothiazepine Derivative, on Limb Blood Flow in Anesthetized Dogs: Selective Suppression of Sympathetic Nerve Activity

N,N′-Diacetyl-l-cystine—the Disulfide Dimer of N-acetylcysteine—Is a Potent Modulator of Contact Sensitivity/Delayed Type Hypersensitivity Reactions in Rodents

[3H]Gemcitabine Uptake by Nucleoside Transporters in a Human Head and Neck Squamous Carcinoma Cell Line

The Interaction of n-Tetraalkylammonium Compounds with a Human Organic Cation Transporter, hOCT1

Acute Effects of Ethanol on Kainate Receptors with Different Subunit Compositions

Neuroprotection of the Developing Brain by Systemic Administration of Vasoactive Intestinal Peptide Derivatives

Endogenous Endothelin-1 Depresses Left Ventricular Systolic and Diastolic Performance in Congestive Heart Failure

Ethanol Exposure Differentially Alters Central Monoamine Neurotransmission in Alcohol-Preferring versus -Nonpreferring Rats

Angiotensin Receptor Subtype 1 Mediates Angiotensin II Enhancement of Isoproterenol-Induced Cyclic AMP Production in Preglomerular Microvascular Smooth Muscle Cells

Inhibition of Prostaglandin Synthesis Up-Regulates Cyclooxygenase-2 Induced by Lipopolysaccharide and Peroxisomal Proliferators

Relaxation of Endothelin-1-Induced Pulmonary Arterial Constriction by Niflumic Acid and NPPB: Mechanism(s) Independent of Chloride Channel Block

N-Oxygenation of Amphetamine and Methamphetamine by the Human Flavin-Containing Monooxygenase (Form 3): Role in Bioactivation and Detoxication

Thioridazine Lengthens Repolarization of Cardiac Ventricular Myocytes by Blocking the Delayed Rectifier Potassium Current

Discriminative Stimulus Effects of Naltrexone After a Single Dose of Morphine in the Rat

O-Raffinose Cross-Linking Markedly Reduces Systemic and Renal Vasoconstrictor Effects of Unmodified Human Hemoglobin

Characterization of the Analgesic and Anti-Inflammatory Activities of Ketorolac and Its Enantiomers in the Rat

Behavioral, Toxic, and Neurochemical Effects of Sydnocarb, a Novel Psychomotor Stimulant: Comparisons with Methamphetamine

Optimization of Magnesium Therapy after Severe Diffuse Axonal Brain Injury in Rats

Increased Lipophilicity and Subsequent Cell Partitioning Decrease Passive Transcellular Diffusion of Novel, Highly Lipophilic Antioxidants

Novel, Highly Lipophilic Antioxidants Readily Diffuse Across the Blood-Brain Barrier and Access Intracellular Sites

Age-Related Reductions in [3H]WIN 35,428 Binding to the Dopamine Transporter in Nigrostriatal and Mesolimbic Brain Regions of the Fischer 344 Rat

Effect of Riluzole on the Neurological and Neuropathological Changes in an Animal Model of Cardiac Arrest-Induced Movement Disorder

Potent Mast Cell Degranulation and Vascular Permeability Triggered by Urocortin Through Activation of Corticotropin-Releasing Hormone Receptors

The Central Cannabinoid Receptor (CB1) Mediates Inhibition of Nitric Oxide Production by Rat Microglial Cells

Evidence for β3-Adrenoceptor Subtypes in Relaxation of the Human Urinary Bladder Detrusor: Analysis by Molecular Biological and Pharmacological Methods

This Issue

Current Issue

(S)-(−)-Cotinine, the Major Brain Metabolite of Nicotine, Stimulates Nicotinic Receptors to Evoke [³H]Dopamine Release from Rat Striatal Slices in a Calcium-Dependent Manner

Inhibition of Transient and Persistent Na⁺ Current Fractions by the New Anticonvulsant Topiramate

Comparison of Functional Antagonism Between Isoproterenol and M₂ Muscarinic Receptors in Guinea Pig Ileum and Trachea

S-16924 [(R)-2-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-pyrrolidin-3yl}-1-(4-fluorophenyl)-ethanone], a Novel, Potential Antipsychotic with Marked Serotonin_1AAgonist Properties: III. Anxiolytic Actions in Comparison with Clozapine and Haloperidol

Kinetic Analysis of Drug-Receptor Interactions of Long-Acting β₂ Sympathomimetics in Isolated Receptor Membranes: Evidence against Prolonged Effects of Salmeterol and Formoterol on Receptor-Coupled Adenylyl Cyclase

Mechanisms of Prostaglandin E₂ Release by Intact Cells Expressing Cyclooxygenase-2: Evidence for a ‘Two-Component’ Model

Pharmacology of LY315920/S-5920,[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A₂Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI

Selective Antiaggressive Effects of Alnespirone in Resident-Intruder Test Are Mediated via 5-Hydroxytryptamine_1A Receptors: A Comparative Pharmacological Study with 8-Hydroxy-2-Dipropylaminotetralin, Ipsapirone, Buspirone, Eltoprazine, and WAY-100635

Development of Muscarinic Analgesics Derived from Epibatidine: Role of the M₄ Receptor Subtype

[³H]Gemcitabine Uptake by Nucleoside Transporters in a Human Head and Neck Squamous Carcinoma Cell Line

Age-Related Reductions in [³H]WIN 35,428 Binding to the Dopamine Transporter in Nigrostriatal and Mesolimbic Brain Regions of the Fischer 344 Rat

Evidence for β₃-Adrenoceptor Subtypes in Relaxation of the Human Urinary Bladder Detrusor: Analysis by Molecular Biological and Pharmacological Methods