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OtherDRUG METABOLISM AND DISPOSITION

Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats

Xiao-Yan Chu, Yukio Kato, Kayoko Niinuma, Ken-Ichi Sudo, Hideo Hakusui and Yuichi Sugiyama
Journal of Pharmacology and Experimental Therapeutics April 1997, 281 (1) 304-314;
Xiao-Yan Chu
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Yukio Kato
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Kayoko Niinuma
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Ken-Ichi Sudo
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Hideo Hakusui
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Yuichi Sugiyama
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Article Information

vol. 281 no. 1 304-314
PubMed 
9103511

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 10, 1996
  • Accepted December 6, 1996
  • Published online April 1, 1997.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Xiao-Yan Chu1,
  2. Yukio Kato1,
  3. Kayoko Niinuma1,
  4. Ken-Ichi Sudo2,
  5. Hideo Hakusui2 and
  6. Yuichi Sugiyama1
  1. 1Faculty of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan (X.-Y.C., Y.K., K.N., Y.S.), and 2Drug Metabolism and Analytical Chemistry Research Center, Developmental Research Laboratories, Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan (K.-I.S., H.H.)
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    Journal of Pharmacology and Experimental Therapeutics
    Vol. 281, Issue 1
    1 Apr 1997
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    OtherDRUG METABOLISM AND DISPOSITION

    Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats

    Xiao-Yan Chu, Yukio Kato, Kayoko Niinuma, Ken-Ichi Sudo, Hideo Hakusui and Yuichi Sugiyama
    Journal of Pharmacology and Experimental Therapeutics April 1, 1997, 281 (1) 304-314;

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    OtherDRUG METABOLISM AND DISPOSITION

    Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats

    Xiao-Yan Chu, Yukio Kato, Kayoko Niinuma, Ken-Ichi Sudo, Hideo Hakusui and Yuichi Sugiyama
    Journal of Pharmacology and Experimental Therapeutics April 1, 1997, 281 (1) 304-314;
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    • Characterization of Efflux Transport of Organic Anions in a Mouse Brain Capillary Endothelial Cell Line
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