Table of Contents

April 1997; 281 (1)

DRUG METABOLISM AND DISPOSITION

    • Gilles Rivière,
    • Valérie Choumet,
    • Françoise Audebert,
    • Alain Sabouraud,
    • Marcel Debray,
    • Jean-Michel Scherrmann,
    • and Cassian Bon

    Effect of Antivenom on Venom Pharmacokinetics in Experimentally Envenomed Rabbits: Toward an Optimization of Antivenom Therapy

    J Pharmacol Exp Ther April 1, 1997 281:1-8
    • Charles F. Minto,
    • Christopher Howe,
    • Susan Wishart,
    • Ann J. Conway,
    • and David J. Handelsman

    Pharmacokinetics and Pharmacodynamics of Nandrolone Esters in Oil Vehicle: Effects of Ester, Injection Site and Injection Volume

    J Pharmacol Exp Ther April 1, 1997 281:93-102
    • Howard L. Kaplan,
    • Usoa E. Busto,
    • Godofredo J. Baylon,
    • Siu W. Cheung,
    • S. Victoria Otton,
    • Gail Somer,
    • and Edward M. Sellers

    Inhibition of Cytochrome P450 2D6 Metabolism of Hydrocodone to Hydromorphone Does Not Importantly Affect Abuse Liability

    J Pharmacol Exp Ther April 1, 1997 281:103-108
    • Harumi Takahashi,
    • Richard B. Kim,
    • Patrick R. Perry,
    • and Grant R. Wilkinson

    Characterization of the Hepatic Canalicular Membrane Transport of a Model Oligopeptide: Ditekiren

    J Pharmacol Exp Ther April 1, 1997 281:297-303
    • Xiao-Yan Chu,
    • Yukio Kato,
    • Kayoko Niinuma,
    • Ken-Ichi Sudo,
    • Hideo Hakusui,
    • and Yuichi Sugiyama

    Multispecific Organic Anion Transporter Is Responsible for the Biliary Excretion of the Camptothecin Derivative Irinotecan and its Metabolites in Rats

    J Pharmacol Exp Ther April 1, 1997 281:304-314
    • Katsuko Takasawa,
    • Tetsuya Terasaki,
    • Hiroshi Suzuki,
    • and Yuichi Sugiyama

    In Vivo Evidence for Carrier-Mediated Efflux Transport of 3′-Azido-3′-Deoxythymidine and 2′,3′-Dideoxyinosine Across the Blood-Brain Barriervia a Probenecid-Sensitive Transport System

    J Pharmacol Exp Ther April 1, 1997 281:369-375
    • Douglas K. Spracklin,
    • Douglas C. Hankins,
    • Jeannine M. Fisher,
    • Kenneth E. Thummel,
    • and Evan D. Kharasch

    Cytochrome P450 2E1 is the Principal Catalyst of Human Oxidative Halothane Metabolism in Vitro

    J Pharmacol Exp Ther April 1, 1997 281:400-411
    • Michiteru Ohtani,
    • Hajime Kotaki,
    • Kenji Nishitateno,
    • Yasufumi Sawada,
    • and Tatsuji Iga

    Kinetics of Respiratory Depression in Rats Induced by Buprenorphine and its Metabolite, Norbuprenorphine

    J Pharmacol Exp Ther April 1, 1997 281:428-433
    • M. Teresa Donato,
    • M. Isabel Guillén,
    • Ramiro Jover,
    • José V. Castell,
    • and M. José Gómez-Lechón

    Nitric Oxide-Mediated Inhibition of Cytochrome P450 by Interferon-γ in Human Hepatocytes

    J Pharmacol Exp Ther April 1, 1997 281:484-490
    • Zhou-Sheng Xiao,
    • Joyce A. Goldstein,
    • Hong-Guang Xie,
    • Joyce Blaisdell,
    • Wei Wang,
    • Chang-Hong Jiang,
    • Feng-Xiang Yan,
    • Nan He,
    • Song-Ling Huang,
    • Zhen-Hua Xu,
    • and Hong-Hao Zhou

    Differences in the Incidence of the CYP2C19Polymorphism Affecting the S-Mephenytoin Phenotype in Chinese Han and Bai Populations and Identification of a New RareCYP2C19 Mutant Allele

    J Pharmacol Exp Ther April 1, 1997 281:604-609

CARDIOVASCULAR PHARMACOLOGY

    • Amrita Ahluwalia and
    • Patrick Vallance

    Evidence for Functional Responses to Sensory Nerve Stimulation of Rat Small Mesenteric Veins

    J Pharmacol Exp Ther April 1, 1997 281:9-14
    • Allen W. Gomoll,
    • Russell A. Roth,
    • Robert E. Swillo,
    • Anne J. Baird,
    • Carol S. Sargent,
    • Ronald W. Behling,
    • Harold J. Malone,
    • and Gary J. Grover

    Effect of Timing of Treatment of the Glyburide-Reversible Cardioprotective Activity of BMS-180448

    J Pharmacol Exp Ther April 1, 1997 281:24-33
    • Eugene Patterson,
    • Benjamin J. Scherlag,
    • Subiah Sangiah,
    • Gregory L. Garrison,
    • Kevin M. Couch,
    • K. Darrell Berlin,
    • and Ralph Lazzara

    Class III Electrophysiologic Actions of Imidazole-Substituted Diheterabicyclononanes in Canine Myocardium

    J Pharmacol Exp Ther April 1, 1997 281:155-162
    • Anthony A. Fossa,
    • Michael J. Depasquale,
    • Jean Morrone,
    • Stevin H. Zorn,
    • Dianne Bryce,
    • John A. Lowe,
    • and Stafford McLean

    Cardiovascular Effects of Cholecystokinin-4 Are Mediated By the Cholecystokinin-B Receptor Subtype In the Conscious Guinea Pig and Dog

    J Pharmacol Exp Ther April 1, 1997 281:180-187
    • Yi-Ching Lo,
    • Jiunn-Ren Wu,
    • Sheng-Nan Wu,
    • and Ing-Jun Chen

    Glyceryl Nonivamide: A Capsaicin Derivative with Cardiac Calcitonin Gene-Related Peptide Releasing, K+ Channel Opening and Vasorelaxant Properties

    J Pharmacol Exp Ther April 1, 1997 281:253-260
    • Randa Hilal-Dandan,
    • Sonia Villegas,
    • Annette Gonzalez,
    • and Laurence L. Brunton

    The Quasi-irreversible Nature of Endothelin Binding and G Protein-Linked Signaling in Cardiac Myocytes

    J Pharmacol Exp Ther April 1, 1997 281:267-273
    • David S. Feldman and
    • Jerry J. Buccafusco

    Spinal Muscarinic, Glutamatergic and GABAergic Receptor Systems in Cardiovascular Regulation

    J Pharmacol Exp Ther April 1, 1997 281:274-283
    • Antonia Brizzolara-Gourdie and
    • Jerry G. Webb

    Angiotensin II Potentiates Vasodilation of Rat Aorta by cAMP Elevating Agonists

    J Pharmacol Exp Ther April 1, 1997 281:354-359
    • Jianlin Feng,
    • Zhiguo Wang,
    • Gui-Rong Li,
    • and Stanley Nattel

    Effects of Class III Antiarrhythmic Drugs on Transient Outward and Ultra-rapid Delayed Rectifier Currents in Human Atrial Myocytes

    J Pharmacol Exp Ther April 1, 1997 281:384-392
    • P. M. Ter Wee,
    • H. G. Forster,
    • and M. Epstein

    Video-microscopic Assessment of the Role of Tissue Angiotensin-converting Enzyme in the Control of the Renal Microcirculation

    J Pharmacol Exp Ther April 1, 1997 281:434-439
    • Cynthia J. Meininger and
    • Guoyao Wu

    l-Glutamine Inhibits Nitric Oxide Synthesis in Bovine Venular Endothelial Cells

    J Pharmacol Exp Ther April 1, 1997 281:448-453

CELLULAR AND MOLECULAR PHARMACOLOGY

    • Sandrine Naze,
    • Hervé Le Stunff,
    • Lien Dokhac,
    • Gisèle Thomas,
    • and Simone Harbon

    Activation of Phospholipase D by Endothelin-1 in Rat Myometrium. Role of Calcium and Protein Kinase C

    J Pharmacol Exp Ther April 1, 1997 281:15-23
    • S. I. Alekseev,
    • A. S. Alekseev,
    • and M. C. Ziskin

    Effects of Alcohols on A-Type K+ Currents inLymnaea Neurons

    J Pharmacol Exp Ther April 1, 1997 281:84-92
    • Masafumi Hagiwara,
    • Satomi Adachi-Akahane,
    • and Taku Nagao

    High-Affinity Binding of DTZ323, a Novel Derivative of Diltiazem, to Rabbit Skeletal Muscle L-type Ca++ Channels

    J Pharmacol Exp Ther April 1, 1997 281:173-179
    • Nancy Bowling,
    • William E. Bloomquist,
    • Marlene L. Cohen,
    • Henry U. Bryant,
    • Harlan W. Cole,
    • David E. Magee,
    • Ellen R. Rowley,
    • and Chris J. Vlahos

    Effects of Prolonged Ethinyl Estradiol Treatment on Calcium Channel Binding and In Vivo Calcium-Mediated Hemodynamic Responses in Ovariectomized Rats

    J Pharmacol Exp Ther April 1, 1997 281:218-225
    • Chang Mann Ko,
    • Ivan Ducic,
    • Jing Fan,
    • Yaroslav M. Shuba,
    • and Martin Morad

    Suppression of Mammalian K+ Channel Family by Ebastine

    J Pharmacol Exp Ther April 1, 1997 281:233-244
    • Jian Huang and
    • John E. Casida

    Avermectin B1a Binds to High- and Low-Affinity Sites with Dual Effects on the γ-Aminobutyric Acid-Gated Chloride Channel of Cultured Cerebellar Granule Neurons

    J Pharmacol Exp Ther April 1, 1997 281:261-266
    • Stephanie L. Borgl and
    • and Fiona E. Parkinson

    Uptake and Release of [3H]Formycin Bvia Sodium-Dependent Nucleoside Transporters in Mouse Leukemic L1210/MA27.1 Cells

    J Pharmacol Exp Ther April 1, 1997 281:347-353
    • G. A. R. Mealing,
    • T. H. Lanthorn,
    • D. L. Small,
    • M. A. Black,
    • N. B. Laferriere,
    • and P. Morley

    Antagonism ofN-Methyl-d-aspartate-evoked Currents in Rat Cortical Cultures by ARL 15896AR

    J Pharmacol Exp Ther April 1, 1997 281:376-383
    • Julius D. Militante,
    • Douglas L. Feinstein,
    • and Peter J. Syapin

    Suppression by Ethanol of Inducible Nitric Oxide Synthase Expression in C6 Glioma Cells

    J Pharmacol Exp Ther April 1, 1997 281:558-565

GASTROINTESTINAL PHARMACOLOGY

    • Richard H. Moseley,
    • Lena J. Zugger,
    • and Rebecca W. Van Dyke

    The Neurotoxin 1-Methyl-4-phenylpyridinium Is a Substrate for the Canalicular Organic Cation/H+ Exchanger

    J Pharmacol Exp Ther April 1, 1997 281:34-40
    • Koji Takeuchi,
    • Koji Takehara,
    • Kimihito Tajima,
    • Shinichi Kato,
    • and Takuya Hirata

    Impaired Healing of Gastric Lesions in Streptozotocin-Induced Diabetic Rats: Effect of Basic Fibroblast Growth Factor

    J Pharmacol Exp Ther April 1, 1997 281:200-207
    • K. Aurang,
    • J. Wang,
    • and K. C. K. Lloyd

    Somatostatin Inhibition of Acid and Histamine Release by Activation of Somatostatin Receptor Subtype 2 Receptors in Rats

    J Pharmacol Exp Ther April 1, 1997 281:245-252
    • Yasunori Nagakura,
    • Akiko Kontoh,
    • Kenichi Tokita,
    • Masaaki Tomoi,
    • Kyoichi Shimomura,
    • and Makoto Kadowaki

    Combined Blockade of 5-HT3- and 5-HT4-Serotonin Receptors Inhibits Colonic Functions in Conscious Rats and Mice

    J Pharmacol Exp Ther April 1, 1997 281:284-290
    • Chi Dae Kim and
    • Ki Whan Hong

    Preventive Effect of Rebamipide on Gastric Mucosal Cell Damage Evoked by Activation of Formyl-Methionyl-Leucyl-Phenylalanine Receptors of Rabbit Neutrophils

    J Pharmacol Exp Ther April 1, 1997 281:478-483

ANALGESIA AND DRUGS OF ABUSE

    • Jianzhong Meng,
    • C. J. Malanga,
    • Jian-Qiang Kong,
    • David A. Taylor,
    • and William W. Fleming

    Hyperpolarizing Effects of Morphine, Clonidine and 2-Chloroadenosine in Myenteric Neurons Associated with Tolerance to Morphine

    J Pharmacol Exp Ther April 1, 1997 281:41-47
    • Grace C. Rossi,
    • Liza Leventhal,
    • Ying-Xin Pan,
    • Jessica Cole,
    • Wendy Su,
    • Richard J. Bodnar,
    • and Gavril W. Pasternak

    Antisense Mapping of MOR-1 in Rats: Distinguishing between Morphine and Morphine-6β-glucuronide Antinociception

    J Pharmacol Exp Ther April 1, 1997 281:109-114
    • Janice Ho,
    • Andrew J. Mannes,
    • Ronald Dubner,
    • and Robert M. Caudle

    Putative kappa-2 Opioid Agonists Are Antihyperalgesic in a Rat Model of Inflammation

    J Pharmacol Exp Ther April 1, 1997 281:136-141
    • Prisca Honoré,
    • Jaroslava Buritova,
    • Marie-Claude Fournié-Zaluski,
    • Bernard P. Roques,
    • and Jean-Marie Besson

    Antinociceptive Effects of RB101, a Complete Inhibitor of Enkephalin-catabolizing Enzymes, Are Enhanced by a Cholecystokinin Type B Receptor Antagonist, as Revealed by Noxiously Evoked Spinal c-Fos Expression in Rats

    J Pharmacol Exp Ther April 1, 1997 281:208-217
    • J. Frank Hoke,
    • Francesca Cunningham,
    • Michael K. James,
    • Keith T. Muir,
    • and William E. Hoffman

    Comparative Pharmacokinetics and Pharmacodynamics of Remifentanil, Its Principle Metabolite (GR90291) and Alfentanil in Dogs

    J Pharmacol Exp Ther April 1, 1997 281:226-232
    • Nobuaki Takeshita and
    • Isamu Yamaguchi

    Insulin Attenuates Formalin-Induced Nociceptive Response in Mice through a Mechanism that Is Deranged by Diabetes Mellitus

    J Pharmacol Exp Ther April 1, 1997 281:315-321
    • Yoseph Caraco,
    • James Sheller,
    • and Alastair J. J. Wood

    Pharmacogenetic Determinants of Codeine Induction by Rifampin: The Impact on Codeine’s Respiratory, Psychomotor and Miotic Effects

    J Pharmacol Exp Ther April 1, 1997 281:330-336
    • Li Xin,
    • Ellen B. Geller,
    • and Martin W. Adler

    Body Temperature and Analgesic Effects of Selective Muand Kappa Opioid Receptor Agonists Microdialyzed into Rat Brain

    J Pharmacol Exp Ther April 1, 1997 281:499-507
    • Suzanne R. Thornton and
    • Forrest L. Smith

    Characterization of Neonatal Rat Fentanyl Tolerance and Dependence

    J Pharmacol Exp Ther April 1, 1997 281:514-521
    • Javier Garzón,
    • Antonio García-España,
    • and Pilar Sánchez-Blázquez

    Opioids Binding Mu and DeltaReceptors Exhibit Diverse Efficacy in the Activation of Gi2and Gx/z Transducer Proteins in Mouse Periaqueductal Gray Matter

    J Pharmacol Exp Ther April 1, 1997 281:549-557
    • S. R. Shelnutt,
    • L. E. Cornett,
    • and S. M. Owens

    Phencyclidine Continuous Dosing Produces a Treatment Time-Dependent Regulation of Rat CYP2C11 Function, Protein Expression and mRNA Levels

    J Pharmacol Exp Ther April 1, 1997 281:574-581
    • Josephine Lai,
    • Tracy J. Crook,
    • Andrea Payne,
    • Ronald M. Lynch,
    • and Frank Porreca

    Antisense Targeting of Delta Opioid Receptors in NG 108-15 Cells: Direct Correlation between Oligodeoxynucleotide Uptake and Receptor Density

    J Pharmacol Exp Ther April 1, 1997 281:589-596

RENAL PHARMACOLOGY

    • H. D. Intengan and
    • D. D. Smyth

    Alpha-2a/d Adrenoceptor Subtype Stimulation by Guanfacine Increases Osmolar Clearance

    J Pharmacol Exp Ther April 1, 1997 281:48-53
    • Alexander J. Rouch,
    • Lúcia H. Kudo,
    • and Connie Hébert

    Dexmedetomidine Inhibits Osmotic Water Permeability in the Rat Cortical Collecting Duct

    J Pharmacol Exp Ther April 1, 1997 281:62-69

NEUROPHARMACOLOGY

    • Barbara A. Sorg,
    • Debra L. Davidson,
    • Peter W. Kalivas,
    • and Balakrishna M. Prasad

    Repeated Daily Cocaine Alters Subsequent Cocaine-induced Increase of Extracellular Dopamine in the Medial Prefrontal Cortex

    J Pharmacol Exp Ther April 1, 1997 281:54-61
    • Sheryl G. Beck,
    • Susanne Birnstiel,
    • Kue C. Choi,
    • and Wendy A. Pouliot

    Fluoxetine Selectively Alters 5-Hydroxytryptamine1Aand γ-Aminobutyric AcidB Receptor-Mediated Hyperpolarization in Area CA1, but not Area CA3, Hippocampal Pyramidal Cells

    J Pharmacol Exp Ther April 1, 1997 281:115-122
    • Wenzhen Jin,
    • Gregory W. Terman,
    • and Charles Chavkin

    Kappa Opioid Receptor Tolerance in the Guinea Pig Hippocampus

    J Pharmacol Exp Ther April 1, 1997 281:123-128
    • Ismail H. Ulus and
    • Richard J. Wurtman

    Metabotropic Glutamate Receptor Agonists Increase Release of Soluble Amyloid Precursor Protein Derivatives from Rat Brain Cortical and Hippocampal Slices

    J Pharmacol Exp Ther April 1, 1997 281:149-154
    • Andre L. Curtis,
    • Sandra M. Lechner,
    • Luis A. Pavcovich,
    • and Rita J. Valentino

    Activation of the Locus Coeruleus Noradrenergic System by Intracoerulear Microinfusion of Corticotropin-Releasing Factor: Effects on Discharge Rate, Cortical Norepinephrine Levels and Cortical Electroencephalographic Activity

    J Pharmacol Exp Ther April 1, 1997 281:163-172
    • Elio Acquas,
    • Catriona Wilson,
    • and Hans C. Fibiger

    Nonstriatal Dopamine D1 Receptors Regulate Striatal Acetylcholine Release In Vivo

    J Pharmacol Exp Ther April 1, 1997 281:360-368
    • K. E. Asin,
    • E. F. Domino,
    • A. Nikkel,
    • and K. Shiosaki

    The Selective Dopamine D1 Receptor Agonist A-86929 Maintains Efficacy with Repeated Treatment in Rodent and Primate Models of Parkinson’s Disease

    J Pharmacol Exp Ther April 1, 1997 281:454-459
    • Srihari R. Tella,
    • Bruce Ladenheim,
    • and Jean Lud Cadet

    Differential Regulation of Dopamine Transporter after Chronic Self-administration of Bupropion and Nomifensine

    J Pharmacol Exp Ther April 1, 1997 281:508-513
    • Ratan V. Bhat,
    • Thomas M. Engber,
    • Yuan Zhu,
    • Matthew S. Miller,
    • and Patricia C. Contreras

    Identification of Insulin-Like Growth Factor Binding Protein-2 as a Biochemical Surrogate Marker for the in Vivo Effects of Recombinant Human Insulin-Like Growth Factor-1 in Mice

    J Pharmacol Exp Ther April 1, 1997 281:522-530
    • M. A. Parada,
    • L. Hernandez,
    • M. Puig De Parada,
    • P. Rada,
    • and E. Murzi

    Selective Action of Acute Systemic Clozapine on Acetylcholine Release in the Rat Prefrontal Cortex by Reference to the Nucleus Accumbens and Striatum

    J Pharmacol Exp Ther April 1, 1997 281:582-588
    • Michael S. Lidow,
    • John D. Elsworth,
    • and Patricia S. Goldman-Rakic

    Down-Regulation of the D1 and D5 Dopamine Receptors in the Primate Prefrontal Cortex by Chronic Treatment with Antipsychotic Drugs

    J Pharmacol Exp Ther April 1, 1997 281:597-603

ENDOCRINE PHARMACOLOGY

    • Nancy K. Mello,
    • Jack H. Mendelson,
    • Maureen Kelly,
    • Nicolas Diaz-Migoyo,
    • and J. Wallis Sholar

    The Effects of Chronic Cocaine Self-Administration on the Menstrual Cycle in Rhesus Monkeys

    J Pharmacol Exp Ther April 1, 1997 281:70-83
    • Cindy C. Taylor,
    • Dunli Wu,
    • Yi Soong,
    • Jenny S. Yee,
    • and Hazel H. Szeto

    Opioid Modulation of the Fetal Hypothalamic-Pituitary-Adrenal Axis: The Role of Receptor Subtypes and Route of Administration

    J Pharmacol Exp Ther April 1, 1997 281:129-135
    • Vincent A. Dipippo and
    • C. Andrew Powers

    Tamoxifen and ICI 182,780 Interactions with Thyroid Hormone in the Ovariectomized-Thyroidectomized Rat

    J Pharmacol Exp Ther April 1, 1997 281:142-148
    • Joy L. Stone,
    • Joel B. Braunstein,
    • Timothy M. Beaty,
    • Ruth A. Sanders,
    • and John B. Watkins III

    Hepatobiliary Excretion of Bile Acids and Rose Bengal in Streptozotocin-Induced and Genetic Diabetic Rats

    J Pharmacol Exp Ther April 1, 1997 281:412-419

BEHAVIORAL PHARMACOLOGY

    • Keith W. Easterling and
    • Stephen G. Holtzman

    Intracranial Self-Stimulation in Rats: Sensitization to an Opioid Antagonist Following Acute or Chronic Treatment with MuOpioid Agonists ,

    J Pharmacol Exp Ther April 1, 1997 281:188-199
    • A. H. Tang,
    • S. R. Franklin,
    • C. S. Himes,
    • M. W. Smith,
    • and R. E. Tenbrink

    PNU-96415E, a Potential Antipsychotic Agent with Clozapine-Like Pharmacological Properties

    J Pharmacol Exp Ther April 1, 1997 281:440-447

AUTONOMIC PHARMACOLOGY

    • Brian Kennedy,
    • Gregory H. Shen,
    • and Michael G. Ziegler

    Neuropeptide Y-Mediated Pressor Responses Following High-Frequency Stimulation of the Rat Sympathetic Nervous System

    J Pharmacol Exp Ther April 1, 1997 281:291-296
    • Xing Fei Deng,
    • Shree Mulay,
    • Sylvain Chemtob,
    • and Daya R. Varma

    Mechanisms of the Atrium-Specific Positive Inotropic Activities of Quinidine- and Atropine-Like Agents in Rats

    J Pharmacol Exp Ther April 1, 1997 281:322-329
    • John W. Hubbard,
    • Scott T. Nordstrom,
    • Craig P. Smith,
    • Karen M. Brooks,
    • Lynn Laws-Ricker,
    • Lily Zhou,
    • and Hugo M. Vargas

    α-Adrenergic Activity and Cardiovascular Effects of Besipirdine HCl (HP 749) and Metabolite P7480 in Vitro and in the Conscious Rat and Dog

    J Pharmacol Exp Ther April 1, 1997 281:337-346
    • Enzo Poli,
    • Cristina Pozzoli,
    • and Giulio Bertaccini

    Interaction Between Histamine H3 Receptors and Other Prejunctional Receptor Systems in the Isolated Guinea Pig Duodenum ,

    J Pharmacol Exp Ther April 1, 1997 281:393-399
    • A. U. Höglund and
    • H. A. Baghdoyan

    M2, M3 and M4, but not M1, Muscarinic Receptor Subtypes are Present in Rat Spinal Cord

    J Pharmacol Exp Ther April 1, 1997 281:470-477
    • Anne Cadène,
    • Florin Grigorescu,
    • Jean-Jacques Serrano,
    • and Gérard Cros

    Characterization of Vanadyl Sulfate Effect on Vascular Contraction: Roles of Calcium and Tyrosine Phosphorylation

    J Pharmacol Exp Ther April 1, 1997 281:491-498

CHEMOTHERAPY/GENE THERAPY

    • Florence I. Raynaud,
    • Rosanne M. Orr,
    • Phyllis M. Goddard,
    • Heidi A. Lacey,
    • Helen Lancashire,
    • Ian R. Judson,
    • Terry Beck,
    • Bob Bryan,
    • and Finbarr E. Cotter

    Pharmacokinetics of G3139, a Phosphorothioate Oligodeoxynucleotide Antisense to bcl-2, after Intravenous Administration or Continuous Subcutaneous Infusion to Mice

    J Pharmacol Exp Ther April 1, 1997 281:420-427
    • Ru-Kun He and
    • Marielle Gascon-Barré

    Influence of the Vitamin D Status on the Early Hepatic Response to Carcinogen Exposure in Rats

    J Pharmacol Exp Ther April 1, 1997 281:464-469
    • Howard J. Lim,
    • Dana Masin,
    • Thomas D. Madden,
    • and Marcel B. Bally

    Influence of Drug Release Characteristics on the Therapeutic Activity of Liposomal Mitoxantrone

    J Pharmacol Exp Ther April 1, 1997 281:566-573

PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS

    • Hasan Safayhi,
    • Beatrice Rall,
    • Eckart-Roderich Sailer,
    • and Hermann P T. Ammon

    Inhibition by Boswellic Acids of Human Leukocyte Elastase

    J Pharmacol Exp Ther April 1, 1997 281:460-463

PULMONARY PHARMACOLOGY

    • Shigeji Matsumoto

    Functional Evidence of Excitatory M1 Receptors in the Rabbit Airway

    J Pharmacol Exp Ther April 1, 1997 281:531-539

IMMUNOPHARMACOLOGY

    • David A. Hess,
    • Ingrid A. Bird,
    • Wassim Y. Almawi,
    • and Michael J. Rieder

    The Hydroxylamine of Sulfamethoxazole Synergizes with FK506 and Cyclosporin A, Inhibiting T-Cell Proliferation

    J Pharmacol Exp Ther April 1, 1997 281:540-548
« Previous | Next Issue »

This Issue

April 1997; 281 (1)
  1. DRUG METABOLISM AND DISPOSITION
  2. CARDIOVASCULAR PHARMACOLOGY
  3. CELLULAR AND MOLECULAR PHARMACOLOGY
  4. GASTROINTESTINAL PHARMACOLOGY
  5. ANALGESIA AND DRUGS OF ABUSE
  6. RENAL PHARMACOLOGY
  7. NEUROPHARMACOLOGY
  8. ENDOCRINE PHARMACOLOGY
  9. BEHAVIORAL PHARMACOLOGY
  10. AUTONOMIC PHARMACOLOGY
  11. CHEMOTHERAPY/GENE THERAPY
  12. PROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS
  13. PULMONARY PHARMACOLOGY
  14. IMMUNOPHARMACOLOGY

Find articles in this issue containing these words:

Current Issue

  1. November 2009, 331 (2)
  1. Current Issue
  1. Alert me to new issues of JPET