Table of Contents

April 1996; 277 (1)

- G A Weisman,
- J T Turner,
- and J S Fedan
Structure and function of P2 purinocepters.
J Pharmacol Exp Ther April 1996 277:1-9
- Full Text (PDF)
- S M Lanier,
- M Lafontan,
- L E Limbird,
- and H Paris
Summary of the ASPET-sponsored Colloquium: Alpha-2 adrenergic receptors: structure, function, and therapeutic implications, October 25-27, 1995.
J Pharmacol Exp Ther April 1996 277:10-16
- Full Text (PDF)
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- P Provost and
- Y Merhi
BW755C, a dual lipoxygenase/cyclooxygenase inhibitor, reduces mural platelet and neutrophil deposition and vasoconstriction after angioplasty injury in pigs.
J Pharmacol Exp Ther April 1996 277:17-21
- Abstract
- Full Text (PDF)
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- M A Oriowo,
- H Chapman,
- D M Kirkham,
- M V Sennitt,
- R R Ruffolo, Jr,
- and M A Cawthorne
The selectivity in vitro of the stereoisomers of the beta-3 adrenoceptor agonist BRL 37344.
J Pharmacol Exp Ther April 1996 277:22-27
- Abstract
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- M Kinoshita,
- N Saito,
- T Noto,
- and H Tamaki
Reversible inhibition of rat gastric H+/K+-ATPase by T-330, 2-[2-dimethylaminobenzyl)sulfinyl]-1-(3-methylpyridine-2-yl)imidazole.
J Pharmacol Exp Ther April 1996 277:28-33
- Abstract
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- C E Costarella,
- J N Stallone,
- G W Rutecki,
- and F C Whittier
Testosterone causes direct relaxation of rat thoracic aorta.
J Pharmacol Exp Ther April 1996 277:34-39
- Abstract
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- R N Iyer and
- C W Bradberry
Serotonin-mediated increase in prefrontal cortex dopamine release: pharmacological characterization.
J Pharmacol Exp Ther April 1996 277:40-47
- Abstract
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- F Brunner,
- K Schmidt,
- E B Nielsen,
- and B Mayer
Novel guanylyl cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery.
J Pharmacol Exp Ther April 1996 277:48-53
- Abstract
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- F Sanae,
- S Ohmae,
- D Kobayashi,
- K Takag,
- and K Miyamoto
Negative inotropic action of denbufylline through interfering with the calcium channel independently of its PDE IV inhibitory activity in guinea pig ventricle papillary muscles.
J Pharmacol Exp Ther April 1996 277:54-60
- Abstract
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- M Endoh,
- I Norota,
- H T Yang,
- S Fujita,
- and M Takanashi
The positive inotropic effect and the hydrolysis of phosphoinositide induced by endothelin-3 in rabbit ventricular myocardium: inhibition by a selective antagonist of ET(A) receptors, FR139317.
J Pharmacol Exp Ther April 1996 277:61-70
- Abstract
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- S Roux,
- T Tschopp,
- and H R Baumgartner
Effects of napsagatran (Ro 46-6240), a new synthetic thrombin inhibitor and of heparin in a canine model of coronary artery thrombosis: comparison with an ex vivo annular perfusion chamber model.
J Pharmacol Exp Ther April 1996 277:71-78
- Abstract
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- M M Barzago,
- A Bortolotti,
- F F Stellari,
- L Diomede,
- M Algeri,
- S Efrati,
- M Salmona,
- and M Bonati
Placental transfer of valproic acid after liposome encapsulation during in vitro human placenta perfusion.
J Pharmacol Exp Ther April 1996 277:79-86
- Abstract
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- J M Witkin,
- J B Acri,
- G Wong,
- S Gleeson,
- and J E Barrett
Behavioral and biochemical characterization of benzodiazepine receptor partial agonists in pigeons.
J Pharmacol Exp Ther April 1996 277:87-96
- Abstract
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- M L Cohen,
- W Bloomquist,
- J M Schaus,
- D C Thompson,
- A D Susemichel,
- D A Calligaro,
- and I Cohen
LY353433, a potent, orally effective, long-acting 5-HT(4) receptor antagonist: comparison to cisapride and RS23597-190.
J Pharmacol Exp Ther April 1996 277:97-104
- Abstract
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- D M Gentile,
- E S Tomlinson,
- J L Maggs,
- B K Park,
- and D J Back
Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation.
J Pharmacol Exp Ther April 1996 277:105-112
- Abstract
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- S M Waters,
- C S Konkoy,
- and T P Davis
Haloperidol and apomorphine differentially affect neuropeptidase activity.
J Pharmacol Exp Ther April 1996 277:113-120
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- A Stefani,
- P Calabresi,
- A Pisani,
- N B Mercuri,
- A Siniscalchi,
- and G Bernardi
Felbamate inhibits dihydropyridine-sensitive calcium channels in central neurons.
J Pharmacol Exp Ther April 1996 277:121-127
- Abstract
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- X L Ma,
- T L Yue,
- B L Lopez,
- F C Barone,
- T A Christopher,
- R R Ruffolo, Jr,
- and G Z Feuerstein
Carvedilol, a new beta adrenoreceptor blocker and free radical scavenger, attenuates myocardial ischemia-reperfusion injury in hypercholesterolemic rabbits.
J Pharmacol Exp Ther April 1996 277:128-136
- Abstract
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- T Inoue,
- M Domae,
- K Yamada,
- and T Furukawa
Effects of the novel antipsychotic agent 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro -2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland.
J Pharmacol Exp Ther April 1996 277:137-143
- Abstract
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- C Hillemeier,
- K N Bitar,
- U Sohn,
- and P Biancani
Protein kinase C mediates spontaneous tone in the cat lower esophageal sphincter.
J Pharmacol Exp Ther April 1996 277:144-149
- Abstract
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- P G Gunasekar,
- P W Sun,
- A G Kanthasamy,
- J L Borowitz,
- and G E Isom
Cyanide-induced neurotoxicity involves nitric oxide and reactive oxygen species generation after N-methyl-D-aspartate receptor activation.
J Pharmacol Exp Ther April 1996 277:150-155
- Abstract
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- P Lebrun,
- M H Antoine,
- R Ouedraogo,
- C Kane,
- M Dunne,
- M Hermann,
- A Herchuelz,
- B Masereel,
- J Delarge,
- P de Tullio,
- and B Pirotte
Activation of ATP-dependent K+ channels and inhibition of insulin release: effect of BPDZ 62.
J Pharmacol Exp Ther April 1996 277:156-162
- Abstract
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- A Guia,
- T Chau,
- D Bose,
- and R Bose
Mechanism of cardiac inotropy by phenamil, and epithelial sodium channel blocker.
J Pharmacol Exp Ther April 1996 277:163-173
- Abstract
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- H Fei and
- L H Frame
d-Sotalol terminates reentry by two mechanisms with different dependence on the duration of the excitable gap.
J Pharmacol Exp Ther April 1996 277:174-185
- Abstract
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- C M O'Hara,
- A Uhland-Smith,
- K L O'Malley,
- and R D Todd
Inhibition of dopamine synthesis by dopamine D2 and D3 but not D4 receptors.
J Pharmacol Exp Ther April 1996 277:186-192
- Abstract
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- R M Broad and
- B B Fredholm
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
J Pharmacol Exp Ther April 1996 277:193-197
- Abstract
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- J B Acri,
- B K Siedleck,
- and J M Witkin
Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine.
J Pharmacol Exp Ther April 1996 277:198-206
- Abstract
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- N Hoque,
- A N Hoque,
- H Hashizume,
- K Ichihara,
- and Y Abiko
K-7259, a novel dilazep derivative, and d-propranolol attenuate H2O2-induced cell damage.
J Pharmacol Exp Ther April 1996 277:207-211
- Abstract
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- R L Peltier,
- D H Li,
- D Lytle,
- C M Taylor,
- and M W Emmett-Oglesby
Chronic d-amphetamine or methamphetamine produces cross-tolerance to the discriminative and reinforcing stimulus effects of cocaine.
J Pharmacol Exp Ther April 1996 277:212-218
- Abstract
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- S E Shoaf and
- B Schmall
Pharmacokinetics of alpha-methyl-L-tryptophan in rhesus monkeys and calculation of the lumped constant for estimating the rate of serotonin synthesis.
J Pharmacol Exp Ther April 1996 277:219-224
- Abstract
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- Z Sarnyai,
- N K Mello,
- J H Mendelson,
- M Erös-Sarnyai,
- and G Mercer
Effects of cocaine on pulsatile activity of hypothalamic-pituitary-adrenal axis in male rhesus monkeys: neuroendocrine and behavioral correlates.
J Pharmacol Exp Ther April 1996 277:225-234
- Abstract
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- G Faintrenie and
- A Géloën
Alpha-1 adrenergic regulation of lactate production by white adipocytes.
J Pharmacol Exp Ther April 1996 277:235-238
- Abstract
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- M D Martin,
- T McCann,
- C Naleway,
- J S Woods,
- B G Leroux,
- and A M Bollen
The validity of spot urine samples for low-level occupational mercury exposure assessment and relationship to porphyrin and creatinine excretion rates.
J Pharmacol Exp Ther April 1996 277:239-244
- Abstract
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- M A Sattar and
- E J Johns
Alpha-1 adrenoceptor subtypes involved in mediating adrenergically induced antinatriuresis and antidiuresis in two kidney, one clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats.
J Pharmacol Exp Ther April 1996 277:245-252
- Abstract
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- O Curet,
- G Damoiseau,
- N Aubin,
- N Sontag,
- V Rovei,
- and F X Jarreau
Befloxatone, a new reversible and selective monoamine oxidase-A inhibitor. I. Biochemical profile.
J Pharmacol Exp Ther April 1996 277:253-264
- Abstract
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- D Caille,
- O E Bergis,
- C Fankhauser,
- A Gardes,
- R Adam,
- T Charieras,
- A Grosset,
- V Rovei,
- and F X Jarreau
Befloxatone, a new reversible and selective monoamine oxidase-A inhibitor. II. Pharmacological profile.
J Pharmacol Exp Ther April 1996 277:265-277
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- K Kasamo,
- P Blier,
- and C De Montigny
Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain.
J Pharmacol Exp Ther April 1996 277:278-286
- Abstract
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- C A Lee,
- J H Lillibridge,
- S D Nelson,
- and J T Slattery
Effects of caffeine and theophylline on acetaminophen pharmacokinetics: P450 inhibition and activation.
J Pharmacol Exp Ther April 1996 277:287-291
- Abstract
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- S R Shelnutt,
- T M Badger,
- and S M Owens
Phencyclidine metabolite irreversible binding in the rat: gonadal steroid regulation and CYP2C11.
J Pharmacol Exp Ther April 1996 277:292-298
- Abstract
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- D A Cabrini,
- D J Kyle,
- and J B Calixto
A pharmacological analysis of receptor subtypes and the mechanisms mediating the biphasic response induced by kinins in the rat stomach fundus in vitro.
J Pharmacol Exp Ther April 1996 277:299-307
- Abstract
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- G I Elmer and
- F R George
The role of specific eicosanoids in mediating the acute narcotic effects of ethanol.
J Pharmacol Exp Ther April 1996 277:308-315
- Abstract
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- M Kutzer,
- S Meer,
- S Haller,
- and J Greven
Basolateral glutarate transport by isolated S2 segments of rabbit kidney proximal tubules.
J Pharmacol Exp Ther April 1996 277:316-320
- Abstract
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- M Bourrié,
- V Meunier,
- Y Berger,
- and G Fabre
Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes.
J Pharmacol Exp Ther April 1996 277:321-332
- Abstract
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- G M Campo,
- F Squadrito,
- D Altavilla,
- G Squadrito,
- A Avenoso,
- P Canale,
- M Ioculano,
- A Sperandeo,
- and A P Caputi
Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation.
J Pharmacol Exp Ther April 1996 277:333-340
- Abstract
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- D L Allen,
- W P Hoffman,
- P Marder,
- M R Matchett,
- P A Leiter,
- D L Abbott,
- and R K Wolff
The effects of LY293111Na, a leukotriene B4 receptor antagonist, on the pulmonary neutrophilia and CD11b expression caused by inhalation of a leukotriene B4 aerosol in rhesus monkeys.
J Pharmacol Exp Ther April 1996 277:341-349
- Abstract
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- T Ishibashi,
- C I Lee,
- and E Okabe
Skeletal sarcoplasmic reticulum dysfunction induced by reactive oxygen intermediates derived from photoactivated rose bengal.
J Pharmacol Exp Ther April 1996 277:350-358
- Abstract
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- L H Claye,
- E M Unterwald,
- A Ho,
- and M J Kreek
Both dynorphin A(1-17) [Des-Tyr1]dynorphin A(2-17) inhibit adenylyl cyclase activity in rat caudate putamen.
J Pharmacol Exp Ther April 1996 277:359-365
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- S E Cross,
- Z Wu,
- and M S Roberts
The effect of protein binding on the deep tissue penetration and efflux of dermally applied salicylic acid, lidocaine and diazepam in the perfused rat hindlimb.
J Pharmacol Exp Ther April 1996 277:366-374
- Abstract
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- R M Maiorino,
- Z F Xu,
- and H V Aposhian
Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides.
J Pharmacol Exp Ther April 1996 277:375-384
- Abstract
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- R M Carelli and
- S A Deadwyler
Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats.
J Pharmacol Exp Ther April 1996 277:385-393
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- J Ren,
- E Karpinski,
- and C G Benishin
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
J Pharmacol Exp Ther April 1996 277:394-402
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- D M McKay,
- R Brattsand,
- E Wieslander,
- M Fung,
- K Croitoru,
- and M H Perdue
Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation.
J Pharmacol Exp Ther April 1996 277:403-410
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- S J Mihic and
- R A Harris
Inhibition of rho1 receptor GABAergic currents by alcohols and volatile anesthetics.
J Pharmacol Exp Ther April 1996 277:411-416
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- M D Salducci,
- A M Chauvet-Monges,
- J P Tillement,
- E Albengres,
- B Testa,
- P Carrupt,
- and A Crevat
Trimetazidine reverses calcium accumulation and impairment of phosphorylation induced by cyclosporine A in isolated rat liver mitochondria.
J Pharmacol Exp Ther April 1996 277:417-422
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- G N Kumar,
- A D Rodrigues,
- A M Buko,
- and J F Denissen
Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.
J Pharmacol Exp Ther April 1996 277:423-431
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- R Bonfante-Cabarcas,
- K L Swanson,
- M Alkondon,
- and E X Albuquerque
Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. IV. Regulation by external Ca++ of alpha-bungarotoxin-sensitive receptor function and of rectification induced by internal Mg++.
J Pharmacol Exp Ther April 1996 277:432-444
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- J H Song and
- T Narahashi
Modulation of sodium channels of rat cerebellar Purkinje neurons by the pyrethroid tetramethrin.
J Pharmacol Exp Ther April 1996 277:445-453
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- M I Damaj,
- S P Welch,
- and B R Martin
Characterization and modulation of acute tolerance to nicotine in mice.
J Pharmacol Exp Ther April 1996 277:454-461
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- A Liguori,
- W H Morse,
- and J Bergman
Respiratory effects of opioid full and partial agonists in rhesus monkeys.
J Pharmacol Exp Ther April 1996 277:462-472
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- M van den Buuse,
- S J Morton,
- J L Cornish,
- and G A Head
Prolonged central effects of quinpirole on cardiovascular regulation.
J Pharmacol Exp Ther April 1996 277:473-483
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- E J Bilsky,
- R N Bernstein,
- Z Wang,
- W Sadée,
- and F Porreca
Effects of naloxone and D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice.
J Pharmacol Exp Ther April 1996 277:484-490
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- E J Bilsky,
- R N Bernstein,
- V J Hruby,
- R B Rothman,
- J Lai,
- and F Porreca
Characterization of antinociception to opioid receptor selective agonists after antisense oligodeoxynucleotide-mediated "knock-down" of opioid receptor in vivo.
J Pharmacol Exp Ther April 1996 277:491-501
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- M Kawamura,
- Y Imura,
- N Moriya,
- S Kita,
- H Fukushi,
- H Sugihara,
- K Nishikawa,
- and Z Terashita
Antithrombotic effects of TAK-029, a novel GPIIb/IIIa antagonist, in guinea pigs: comparative studies with ticlopidine, clopidogrel, aspirin, prostaglandin E1 and argatroban.
J Pharmacol Exp Ther April 1996 277:502-510
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- V J Cunningham,
- S D Rosen,
- H Boyd,
- S Osman,
- R J Davenport,
- R N Gunn,
- V W Pike,
- and P G Camici
Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium.
J Pharmacol Exp Ther April 1996 277:511-517
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- H Y Wang,
- E Fiorica-Howells,
- H Pan,
- M D Gershon,
- and E Friedman
Myenteric ganglionic 5-hydroxytryptamine(1P) signal transmission is mediated via Go protein.
J Pharmacol Exp Ther April 1996 277:518-524
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- T M Zheng,
- H J Caruncho,
- W J Zhu,
- S Vicini,
- S Ikonomovic,
- D R Grayson,
- and E Costa
Chronic flumazenil alters GABA(A) receptor subunit mRNA expression, translation product assembly and channel function in neuronal cultures.
J Pharmacol Exp Ther April 1996 277:525-533
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- S C Makrides,
- P A Nygren,
- B Andrews,
- P J Ford,
- K S Evans,
- E G Hayman,
- H Adari,
- M Uhlén,
- and C A Toth
Extended in vivo half-life of human soluble complement receptor type 1 fused to a serum albumin-binding receptor.
J Pharmacol Exp Ther April 1996 277:534-542
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- M Sato,
- H U Bryant,
- J A Dodge,
- H Davis,
- W F Matter,
- and C J Vlahos
Effects of wortmannin analogs on bone in vitro and in vivo.
J Pharmacol Exp Ther April 1996 277:543-550
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- G Zhang,
- A H Lagrange,
- O K Rønnekleiv,
- and M J Kelly
Tolerance of hypothalamic beta-endorphin neurons to mu-opioid receptor activation after chronic morphine.
J Pharmacol Exp Ther April 1996 277:551-558
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Current Issue

November 2009, 331 (2)

Structure and function of P2 purinocepters.

Summary of the ASPET-sponsored Colloquium: Alpha-2 adrenergic receptors: structure, function, and therapeutic implications, October 25-27, 1995.

BW755C, a dual lipoxygenase/cyclooxygenase inhibitor, reduces mural platelet and neutrophil deposition and vasoconstriction after angioplasty injury in pigs.

The selectivity in vitro of the stereoisomers of the beta-3 adrenoceptor agonist BRL 37344.

Reversible inhibition of rat gastric H+/K+-ATPase by T-330, 2-[2-dimethylaminobenzyl)sulfinyl]-1-(3-methylpyridine-2-yl)imidazole.

Testosterone causes direct relaxation of rat thoracic aorta.

Serotonin-mediated increase in prefrontal cortex dopamine release: pharmacological characterization.

Novel guanylyl cyclase inhibitor potently inhibits cyclic GMP accumulation in endothelial cells and relaxation of bovine pulmonary artery.

Negative inotropic action of denbufylline through interfering with the calcium channel independently of its PDE IV inhibitory activity in guinea pig ventricle papillary muscles.

The positive inotropic effect and the hydrolysis of phosphoinositide induced by endothelin-3 in rabbit ventricular myocardium: inhibition by a selective antagonist of ET(A) receptors, FR139317.

Effects of napsagatran (Ro 46-6240), a new synthetic thrombin inhibitor and of heparin in a canine model of coronary artery thrombosis: comparison with an ex vivo annular perfusion chamber model.

Placental transfer of valproic acid after liposome encapsulation during in vitro human placenta perfusion.

Behavioral and biochemical characterization of benzodiazepine receptor partial agonists in pigeons.

LY353433, a potent, orally effective, long-acting 5-HT(4) receptor antagonist: comparison to cisapride and RS23597-190.

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation.

Haloperidol and apomorphine differentially affect neuropeptidase activity.

Felbamate inhibits dihydropyridine-sensitive calcium channels in central neurons.

Carvedilol, a new beta adrenoreceptor blocker and free radical scavenger, attenuates myocardial ischemia-reperfusion injury in hypercholesterolemic rabbits.

Effects of the novel antipsychotic agent 7-(4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro -2(1H)-quinolinone (OPC-14597) on prolactin release from the rat anterior pituitary gland.

Protein kinase C mediates spontaneous tone in the cat lower esophageal sphincter.

Cyanide-induced neurotoxicity involves nitric oxide and reactive oxygen species generation after N-methyl-D-aspartate receptor activation.

Activation of ATP-dependent K+ channels and inhibition of insulin release: effect of BPDZ 62.

Mechanism of cardiac inotropy by phenamil, and epithelial sodium channel blocker.

d-Sotalol terminates reentry by two mechanisms with different dependence on the duration of the excitable gap.

Inhibition of dopamine synthesis by dopamine D2 and D3 but not D4 receptors.

A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.

Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine.

K-7259, a novel dilazep derivative, and d-propranolol attenuate H2O2-induced cell damage.

Chronic d-amphetamine or methamphetamine produces cross-tolerance to the discriminative and reinforcing stimulus effects of cocaine.

Pharmacokinetics of alpha-methyl-L-tryptophan in rhesus monkeys and calculation of the lumped constant for estimating the rate of serotonin synthesis.

Effects of cocaine on pulsatile activity of hypothalamic-pituitary-adrenal axis in male rhesus monkeys: neuroendocrine and behavioral correlates.

Alpha-1 adrenergic regulation of lactate production by white adipocytes.

The validity of spot urine samples for low-level occupational mercury exposure assessment and relationship to porphyrin and creatinine excretion rates.

Alpha-1 adrenoceptor subtypes involved in mediating adrenergically induced antinatriuresis and antidiuresis in two kidney, one clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats.

Befloxatone, a new reversible and selective monoamine oxidase-A inhibitor. I. Biochemical profile.

Befloxatone, a new reversible and selective monoamine oxidase-A inhibitor. II. Pharmacological profile.

Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain.

Effects of caffeine and theophylline on acetaminophen pharmacokinetics: P450 inhibition and activation.

Phencyclidine metabolite irreversible binding in the rat: gonadal steroid regulation and CYP2C11.

A pharmacological analysis of receptor subtypes and the mechanisms mediating the biphasic response induced by kinins in the rat stomach fundus in vitro.

The role of specific eicosanoids in mediating the acute narcotic effects of ethanol.

Basolateral glutarate transport by isolated S2 segments of rabbit kidney proximal tubules.

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes.

Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation.

The effects of LY293111Na, a leukotriene B4 receptor antagonist, on the pulmonary neutrophilia and CD11b expression caused by inhalation of a leukotriene B4 aerosol in rhesus monkeys.

Skeletal sarcoplasmic reticulum dysfunction induced by reactive oxygen intermediates derived from photoactivated rose bengal.

Both dynorphin A(1-17) [Des-Tyr1]dynorphin A(2-17) inhibit adenylyl cyclase activity in rat caudate putamen.

The effect of protein binding on the deep tissue penetration and efflux of dermally applied salicylic acid, lidocaine and diazepam in the perfused rat hindlimb.

Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides.

Dose-dependent transitions in nucleus accumbens cell firing and behavioral responding during cocaine self-administration sessions in rats.

The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.

Budesonide inhibits T cell-initiated epithelial pathophysiology in an in vitro model of inflammation.

Inhibition of rho1 receptor GABAergic currents by alcohols and volatile anesthetics.

Trimetazidine reverses calcium accumulation and impairment of phosphorylation induced by cyclosporine A in isolated rat liver mitochondria.

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. IV. Regulation by external Ca++ of alpha-bungarotoxin-sensitive receptor function and of rectification induced by internal Mg++.

Modulation of sodium channels of rat cerebellar Purkinje neurons by the pyrethroid tetramethrin.

Characterization and modulation of acute tolerance to nicotine in mice.

Respiratory effects of opioid full and partial agonists in rhesus monkeys.

Prolonged central effects of quinpirole on cardiovascular regulation.

Effects of naloxone and D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice.

Characterization of antinociception to opioid receptor selective agonists after antisense oligodeoxynucleotide-mediated "knock-down" of opioid receptor in vivo.

Antithrombotic effects of TAK-029, a novel GPIIb/IIIa antagonist, in guinea pigs: comparative studies with ticlopidine, clopidogrel, aspirin, prostaglandin E1 and argatroban.

Uptake of [N-methyl-11C]propionyl-L-carnitine (PLC) in human myocardium.

Myenteric ganglionic 5-hydroxytryptamine(1P) signal transmission is mediated via Go protein.

Chronic flumazenil alters GABA(A) receptor subunit mRNA expression, translation product assembly and channel function in neuronal cultures.

Extended in vivo half-life of human soluble complement receptor type 1 fused to a serum albumin-binding receptor.

Effects of wortmannin analogs on bone in vitro and in vivo.

Tolerance of hypothalamic beta-endorphin neurons to mu-opioid receptor activation after chronic morphine.

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