Table of Contents

February 1996; 276 (2)

Select this article
- T J Lee,
- S Sarwinski,
- T Ishine,
- C C Lai,
- and F Y Chen
Inhibition of cerebral neurogenic vasodilation by L-glutamine and nitric oxide synthase inhibitors and its reversal by L-citrulline.
J Pharmacol Exp Ther February 1996 276:353-358
- Abstract
- Full Text (PDF)
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- I Limon-Boulez,
- F Tesson,
- C Gargalidis-Moudanos,
- and A Parini
I2-imidazoline binding sites: relationship with different monoamine oxidase domains and identification of histidine residues mediating ligand binding regulation by H+1.
J Pharmacol Exp Ther February 1996 276:359-364
- Abstract
- Full Text (PDF)
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- I R Coe,
- D P Dohrman,
- A Constantinescu,
- I Diamond,
- and A S Gordon
Activation of cyclic AMP-dependent protein kinase reverses tolerance of a nucleoside transporter to ethanol.
J Pharmacol Exp Ther February 1996 276:365-369
- Abstract
- Full Text (PDF)
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- L L von Moltke,
- D J Greenblatt,
- J S Harmatz,
- S X Duan,
- L M Harrel,
- M M Cotreau-Bibbo,
- G A Pritchard,
- C E Wright,
- and R I Shader
Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.
J Pharmacol Exp Ther February 1996 276:370-379
- Abstract
- Full Text (PDF)
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- G J Grover,
- C S Parham,
- D B Whigan,
- and J G Mitroka
BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs.
J Pharmacol Exp Ther February 1996 276:380-387
- Abstract
- Full Text (PDF)
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- M S Kleven and
- W Koek
Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT2A/2C antagonist anxiolytics. I. Antipunishment effects in the pigeon.
J Pharmacol Exp Ther February 1996 276:388-397
- Abstract
- Full Text (PDF)
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- C Zocchi,
- E Ongini,
- A Conti,
- A Monopoli,
- A Negretti,
- P G Baraldi,
- and S Dionisotti
The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist.
J Pharmacol Exp Ther February 1996 276:398-404
- Abstract
- Full Text (PDF)
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- F J Ehlert,
- H S Oliff,
- and M T Griffin
The quaternary transformation products of N-(3-chloropropyl)-4-piperidinyl diphenylacetate and N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) have differential affinity for subtypes of the muscarinic receptor.
J Pharmacol Exp Ther February 1996 276:405-410
- Abstract
- Full Text (PDF)
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- C K Chan,
- F Sannajust,
- and G A Head
Role of imidazoline receptors in the cardiovascular actions of moxonidine, rilmenidine and clonidine in conscious rabbits.
J Pharmacol Exp Ther February 1996 276:411-420
- Abstract
- Full Text (PDF)
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- Y Kita,
- Y Hirasawa,
- S Fukuyama,
- K Ohkubo,
- Y Kato,
- H Takamatsu,
- M Ohno,
- S Nishino,
- M Kato,
- and J Seki
Oral biological activities of spontaneous nitric oxide releasers are accounted for by their nitric oxide-releasing rates and oral absorption manners.
J Pharmacol Exp Ther February 1996 276:421-425
- Abstract
- Full Text (PDF)
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- J R Greene and
- A Mason
Effects of somatostatin and related peptides on the membrane potential and input resistance of rat ventral subicular neurons, in vitro.
J Pharmacol Exp Ther February 1996 276:426-432
- Abstract
- Full Text (PDF)
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- Y Abe,
- R Ishisu,
- K Onishi,
- K Sekioka,
- A Narimatsu,
- and T Nakano
Calcium sensitization in perfused beating guinea pig heart by a positive inotropic agent MCI-154.
J Pharmacol Exp Ther February 1996 276:433-439
- Abstract
- Full Text (PDF)
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- C W Stevens
Relative analgesic potency of mu, delta and kappa opioids after spinal administration in amphibians.
J Pharmacol Exp Ther February 1996 276:440-448
- Abstract
- Full Text (PDF)
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- T Eissenberg,
- M K Greenwald,
- R E Johnson,
- I A Liebson,
- G E Bigelow,
- and M L Stitzer
Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans.
J Pharmacol Exp Ther February 1996 276:449-459
- Abstract
- Full Text (PDF)
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- K Yamada,
- Y Noda,
- T Hasegawa,
- Y Komori,
- T Nikai,
- H Sugihara,
- and T Nabeshima
The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice.
J Pharmacol Exp Ther February 1996 276:460-466
- Abstract
- Full Text (PDF)
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- H Imamura,
- Y Furukawa,
- H Nakano,
- M Kasama,
- Y Hoyano,
- and S Chiba
Selective inhibition by a class III antiarrhythmic agent, E-4031, of the negative chronotropic response to parasympathetic stimulation in anesthetized dogs.
J Pharmacol Exp Ther February 1996 276:467-472
- Abstract
- Full Text (PDF)
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- T J Opgenorth,
- A L Adler,
- S V Calzadilla,
- W J Chiou,
- B D Dayton,
- D B Dixon,
- L J Gehrke,
- L Hernandez,
- S R Magnuson,
- K C Marsh,
- E I Novosad,
- T W Von Geldern,
- J L Wessale,
- M Winn,
- and J R Wu-Wong
Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.
J Pharmacol Exp Ther February 1996 276:473-481
- Abstract
- Full Text (PDF)
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- X Yang,
- H E Criswell,
- and G R Breese
Nicotine-induced inhibition in medial septum involves activation of presynaptic nicotinic cholinergic receptors on gamma-aminobutyric acid-containing neurons.
J Pharmacol Exp Ther February 1996 276:482-489
- Abstract
- Full Text (PDF)
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- P L Martin,
- R J Wysocki, Jr,
- R J Barrett,
- J M May,
- and J Linden
Characterization of 8-(N-methylisopropyl)amino-N6-(5'-endohydroxy- endonorbornyl)-9-methyladenine (WRC-0571), a highly potent and selective, non-xanthine antagonist of A1 adenosine receptors.
J Pharmacol Exp Ther February 1996 276:490-499
- Abstract
- Full Text (PDF)
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- B Y Li,
- J W Nalwalk,
- L A Barker,
- P Cumming,
- M E Parsons,
- and L B Hough
Characterization of the antinociceptive properties of cimetidine and a structural analog.
J Pharmacol Exp Ther February 1996 276:500-508
- Abstract
- Full Text (PDF)
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- A I Sacaan,
- F Menzaghi,
- J L Dunlop,
- L D Correa,
- K T Whelan,
- and G K Lloyd
Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats.
J Pharmacol Exp Ther February 1996 276:509-515
- Abstract
- Full Text (PDF)
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- N O Dalby and
- C Thomsen
Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.
J Pharmacol Exp Ther February 1996 276:516-522
- Abstract
- Full Text (PDF)
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- L R Gerak and
- C P France
Discriminative stimulus effects of nalbuphine in rhesus monkeys.
J Pharmacol Exp Ther February 1996 276:523-531
- Abstract
- Full Text (PDF)
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- J S Mogil,
- B Kest,
- B Sadowski,
- and J K Belknap
Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay.
J Pharmacol Exp Ther February 1996 276:532-544
- Abstract
- Full Text (PDF)
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- T S Shippenberg,
- A LeFevour,
- and C Heidbreder
kappa-Opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine.
J Pharmacol Exp Ther February 1996 276:545-554
- Abstract
- Full Text (PDF)
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- J W Proksch,
- L A Traylor,
- and P R Mayeux
Effects of lipid A on calcium homeostasis in renal proximal tubules.
J Pharmacol Exp Ther February 1996 276:555-560
- Abstract
- Full Text (PDF)
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- R H Moseley,
- H Smit,
- B G Van Solkema,
- W Wang,
- and D K Meijer
Mechanisms for the hepatic uptake and biliary excretion of tributylmethylammonium: studies with rat liver plasma membrane vesicles.
J Pharmacol Exp Ther February 1996 276:561-567
- Abstract
- Full Text (PDF)
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- D Liu,
- R J Hariman,
- and J L Bauman
Cocaine concentration-effect relationship in the presence and absence of lidocaine: evidence of competitive binding between cocaine and lidocaine.
J Pharmacol Exp Ther February 1996 276:568-577
- Abstract
- Full Text (PDF)
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- P Y Sze
Glucocorticoid interactions with ethanol effects on synaptic plasma membranes: influence on [125I]calmodulin binding.
J Pharmacol Exp Ther February 1996 276:578-584
- Abstract
- Full Text (PDF)
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- A H Lichtman,
- S A Cook,
- and B R Martin
Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement.
J Pharmacol Exp Ther February 1996 276:585-593
- Abstract
- Full Text (PDF)
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- R Young and
- R A Glennon
A three-lever operant procedure differentiates the stimulus effects of R(-)-MDA from S(+)-MDA.
J Pharmacol Exp Ther February 1996 276:594-601
- Abstract
- Full Text (PDF)
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- R B Raftogianis,
- M R Franklin,
- and R E Galinsky
Effect of lipid-free total parenteral nutrition on hepatic drug conjugation in rats.
J Pharmacol Exp Ther February 1996 276:602-608
- Abstract
- Full Text (PDF)
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- E H Ohlstein,
- P Nambi,
- A Lago,
- D W Hay,
- G Beck,
- K L Fong,
- E P Eddy,
- P Smith,
- H Ellens,
- and J D Elliott
Nonpeptide endothelin receptor antagonists. VI: Pharmacological characterization of SB 217242, a potent and highly bioavailable endothelin receptor antagonist.
J Pharmacol Exp Ther February 1996 276:609-615
- Abstract
- Full Text (PDF)
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- A Chéramy,
- G Godeheu,
- M L'Hirondel,
- and J Glowinski
Cooperative contributions of cholinergic and NMDA receptors in the presynaptic control of dopamine release from synaptosomes of the rat striatum.
J Pharmacol Exp Ther February 1996 276:616-625
- Abstract
- Full Text (PDF)
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- K Fecho,
- K A Maslonek,
- L A Dykstra,
- and D T Lysle
Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats.
J Pharmacol Exp Ther February 1996 276:626-636
- Abstract
- Full Text (PDF)
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- A Bril,
- B Gout,
- M Bonhomme,
- L Landais,
- J F Faivre,
- P Linee,
- R H Poyser,
- and R R Ruffolo, Jr
Combined potassium and calcium channel blocking activities as a basis for antiarrhythmic efficacy with low proarrhythmic risk: experimental profile of BRL-32872.
J Pharmacol Exp Ther February 1996 276:637-646
- Abstract
- Full Text (PDF)
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- R B Raffa,
- J J Schupsky,
- and H I Jacoby
Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.
J Pharmacol Exp Ther February 1996 276:647-651
- Abstract
- Full Text (PDF)
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- M Y Farhat,
- S Abi-Younes,
- B Dingaan,
- R Vargas,
- and P W Ramwell
Estradiol increases cyclic adenosine monophosphate in rat pulmonary vascular smooth muscle cells by a nongenomic mechanism.
J Pharmacol Exp Ther February 1996 276:652-657
- Abstract
- Full Text (PDF)
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- B J Ring,
- J Catlow,
- T J Lindsay,
- T Gillespie,
- L K Roskos,
- B J Cerimele,
- S P Swanson,
- M A Hamman,
- and S A Wrighton
Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine.
J Pharmacol Exp Ther February 1996 276:658-666
- Abstract
- Full Text (PDF)
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- D L Davies,
- M Bejanian,
- E S Parker,
- J Mørland,
- M B Bolger,
- R D Brinton,
- and R L Alkana
Low level hyperbaric antagonism of diazepam's locomotor depressant and anticonvulsant properties in mice.
J Pharmacol Exp Ther February 1996 276:667-675
- Abstract
- Full Text (PDF)
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- S J Chung,
- V K Ramanathan,
- C M Brett,
- and K M Giacomini
Saturable disposition of taurine in the rat cerebrospinal fluid.
J Pharmacol Exp Ther February 1996 276:676-682
- Abstract
- Full Text (PDF)
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- M R Ujhelyi,
- M B Bottorff,
- M Schur,
- K Roll,
- H Zhang,
- J Stewart,
- and M L Markel
Urine acidification affects the activity of the organic base transporter in a nonstereoselective manner.
J Pharmacol Exp Ther February 1996 276:683-689
- Abstract
- Full Text (PDF)
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- E A Pasyk,
- S Cipris,
- and E E Daniel
A G protein, not cyclic AMP, mediates effects of VIP on the inwardly rectifying K+ channels in endothelial cells.
J Pharmacol Exp Ther February 1996 276:690-696
- Abstract
- Full Text (PDF)
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- G Piñeyro and
- P Blier
Regulation of 5-hydroxytryptamine release from rat midbrain raphe nuclei by 5-hydroxytryptamine1D receptors: effect of tetrodotoxin, G protein inactivation and long-term antidepressant administration.
J Pharmacol Exp Ther February 1996 276:697-707
- Abstract
- Full Text (PDF)
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- A A Seymour,
- M M Asaad,
- B E Abboa-Offei,
- P L Smith,
- W L Rogers,
- and C R Dorso
Determinants of in vivo activity of neutral endopeptidase 3.4.24.11 and angiotensin converting enzyme inhibitors.
J Pharmacol Exp Ther February 1996 276:708-713
- Abstract
- Full Text (PDF)
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- K N Bitar,
- S Kothary,
- and P C Kothary
Somatostatin inhibits bombesin-stimulated Gi-protein via its own receptor in rabbit colonic smooth muscle cells.
J Pharmacol Exp Ther February 1996 276:714-719
- Abstract
- Full Text (PDF)
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- D B Wainscott,
- V L Lucaites,
- J D Kursar,
- M Baez,
- and D L Nelson
Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences.
J Pharmacol Exp Ther February 1996 276:720-727
- Abstract
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- W S Powell,
- J Rokach,
- S P Khanapure,
- S Manna,
- M Hashefi,
- S Gravel,
- R J Macleod,
- J R Falck,
- and R K Bhatt
Effects of metabolites of leukotriene B4 on human neutrophil migration and cytosolic calcium levels.
J Pharmacol Exp Ther February 1996 276:728-736
- Abstract
- Full Text (PDF)
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- I G Campbell and
- I Feinberg
Noncompetitive NMDA channel blockade during waking intensely stimulates NREM delta.
J Pharmacol Exp Ther February 1996 276:737-742
- Abstract
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- A Capasso,
- A Di Giannuario,
- A Loizzo,
- S Pieretti,
- S Sagratella,
- and L Sorrentino
Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues.
J Pharmacol Exp Ther February 1996 276:743-751
- Abstract
- Full Text (PDF)
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- J Haynes, Jr,
- D W Killilea,
- P D Peterson,
- and W J Thompson
Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic-3',5'-guanosine monophosphate-stimulated phosphodiesterase to reverse hypoxic pulmonary vasoconstriction in the perfused rat lung.
J Pharmacol Exp Ther February 1996 276:752-757
- Abstract
- Full Text (PDF)
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- M I Davis-Cox,
- T L Fletcher,
- J N Turner,
- D Szarowski,
- and W Shain
Three-day exposure to low-dose ethanol alters guanine nucleotide binding protein expression in the developing rat hippocampus.
J Pharmacol Exp Ther February 1996 276:758-764
- Abstract
- Full Text (PDF)
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- K Maeda and
- M Fukuda
Arbutin: mechanism of its depigmenting action in human melanocyte culture.
J Pharmacol Exp Ther February 1996 276:765-769
- Abstract
- Full Text (PDF)
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- S F Rosebrough and
- M Hashmi
Galactose-modified streptavidin-GC4 antifibrin monoclonal antibody conjugates: application for two-step thrombus/embolus imaging.
J Pharmacol Exp Ther February 1996 276:770-775
- Abstract
- Full Text (PDF)
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- Y Daaka,
- H Friedman,
- and T W Klein
Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation.
J Pharmacol Exp Ther February 1996 276:776-783
- Abstract
- Full Text (PDF)
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- V A Boundy,
- L Lu,
- and P B Molinoff
Differential coupling of rat D2 dopamine receptor isoforms expressed in Spodoptera frugiperda insect cells.
J Pharmacol Exp Ther February 1996 276:784-794
- Abstract
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- V De Gennaro Colonna,
- M Zoli,
- B P Settembrini,
- S Ciceri,
- A De Marco,
- S G Cella,
- L F Agnati,
- and E E Muller
Effects of single and short-term administration of clonidine on hypothalamic-pituitary somatotropic function of the adult male rat: an in situ hybridization study.
J Pharmacol Exp Ther February 1996 276:795-800
- Abstract
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- K R Gogas,
- J D Levine,
- and A I Basbaum
Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression.
J Pharmacol Exp Ther February 1996 276:801-809
- Abstract
- Full Text (PDF)
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- C D Manning,
- M M McLaughlin,
- G P Livi,
- L B Cieslinski,
- T J Torphy,
- and M S Barnette
Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.
J Pharmacol Exp Ther February 1996 276:810-818
- Abstract
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- M Munir,
- L Lu,
- Y H Wang,
- J Luo,
- B B Wolfe,
- and P McGonigle
Pharmacological and immunological characterization of N-methyl-D-aspartate receptors in human NT2-N neurons.
J Pharmacol Exp Ther February 1996 276:819-828
- Abstract
- Full Text (PDF)
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- K Sakai,
- N Nakahata,
- H Ono,
- T Yamamoto,
- and Y Ohizumi
Homologous desensitization of thromboxane A2 receptor in 1321N1 human astrocytoma cells.
J Pharmacol Exp Ther February 1996 276:829-836
- Abstract
- Full Text (PDF)
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- H Ali,
- O H Choi,
- P F Fraundorfer,
- K Yamada,
- H M Gonzaga,
- and M A Beaven
Sustained activation of phospholipase D via adenosine A3 receptors is associated with enhancement of antigen- and Ca(2+)-ionophore-induced secretion in a rat mast cell line.
J Pharmacol Exp Ther February 1996 276:837-845
- Abstract
- Full Text (PDF)
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- K E Sabol,
- R Lew,
- J B Richards,
- G L Vosmer,
- and L S Seiden
Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations.
J Pharmacol Exp Ther February 1996 276:846-854
- Abstract
- Full Text (PDF)
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- R Lew,
- K E Sabol,
- C Chou,
- G L Vosmer,
- J Richards,
- and L S Seiden
Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies.
J Pharmacol Exp Ther February 1996 276:855-865
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Inhibition of cerebral neurogenic vasodilation by L-glutamine and nitric oxide synthase inhibitors and its reversal by L-citrulline.

I2-imidazoline binding sites: relationship with different monoamine oxidase domains and identification of histidine residues mediating ligand binding regulation by H+1.

Activation of cyclic AMP-dependent protein kinase reverses tolerance of a nucleoside transporter to ethanol.

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.

BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs.

Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT2A/2C antagonist anxiolytics. I. Antipunishment effects in the pigeon.

The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist.

The quaternary transformation products of N-(3-chloropropyl)-4-piperidinyl diphenylacetate and N-(2-chloroethyl)-4-piperidinyl diphenylacetate (4-DAMP mustard) have differential affinity for subtypes of the muscarinic receptor.

Role of imidazoline receptors in the cardiovascular actions of moxonidine, rilmenidine and clonidine in conscious rabbits.

Oral biological activities of spontaneous nitric oxide releasers are accounted for by their nitric oxide-releasing rates and oral absorption manners.

Effects of somatostatin and related peptides on the membrane potential and input resistance of rat ventral subicular neurons, in vitro.

Calcium sensitization in perfused beating guinea pig heart by a positive inotropic agent MCI-154.

Relative analgesic potency of mu, delta and kappa opioids after spinal administration in amphibians.

Buprenorphine's physical dependence potential: antagonist-precipitated withdrawal in humans.

The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice.

Selective inhibition by a class III antiarrhythmic agent, E-4031, of the negative chronotropic response to parasympathetic stimulation in anesthetized dogs.

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

Nicotine-induced inhibition in medial septum involves activation of presynaptic nicotinic cholinergic receptors on gamma-aminobutyric acid-containing neurons.

Characterization of 8-(N-methylisopropyl)amino-N6-(5'-endohydroxy- endonorbornyl)-9-methyladenine (WRC-0571), a highly potent and selective, non-xanthine antagonist of A1 adenosine receptors.

Characterization of the antinociceptive properties of cimetidine and a structural analog.

Epibatidine: a nicotinic acetylcholine receptor agonist releases monoaminergic neurotransmitters: in vitro and in vivo evidence in rats.

Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.

Discriminative stimulus effects of nalbuphine in rhesus monkeys.

Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: influence of nociceptive assay.

kappa-Opioid receptor agonists prevent sensitization to the conditioned rewarding effects of cocaine.

Effects of lipid A on calcium homeostasis in renal proximal tubules.

Mechanisms for the hepatic uptake and biliary excretion of tributylmethylammonium: studies with rat liver plasma membrane vesicles.

Cocaine concentration-effect relationship in the presence and absence of lidocaine: evidence of competitive binding between cocaine and lidocaine.

Glucocorticoid interactions with ethanol effects on synaptic plasma membranes: influence on [125I]calmodulin binding.

Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement.

A three-lever operant procedure differentiates the stimulus effects of R(-)-MDA from S(+)-MDA.

Effect of lipid-free total parenteral nutrition on hepatic drug conjugation in rats.

Nonpeptide endothelin receptor antagonists. VI: Pharmacological characterization of SB 217242, a potent and highly bioavailable endothelin receptor antagonist.

Cooperative contributions of cholinergic and NMDA receptors in the presynaptic control of dopamine release from synaptosomes of the rat striatum.

Assessment of the involvement of central nervous system and peripheral opioid receptors in the immunomodulatory effects of acute morphine treatment in rats.

Combined potassium and calcium channel blocking activities as a basis for antiarrhythmic efficacy with low proarrhythmic risk: experimental profile of BRL-32872.

Endothelin-induced nociception in mice: mediation by ETA and ETB receptors.

Estradiol increases cyclic adenosine monophosphate in rat pulmonary vascular smooth muscle cells by a nongenomic mechanism.

Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine.

Low level hyperbaric antagonism of diazepam's locomotor depressant and anticonvulsant properties in mice.

Saturable disposition of taurine in the rat cerebrospinal fluid.

Urine acidification affects the activity of the organic base transporter in a nonstereoselective manner.

A G protein, not cyclic AMP, mediates effects of VIP on the inwardly rectifying K+ channels in endothelial cells.

Regulation of 5-hydroxytryptamine release from rat midbrain raphe nuclei by 5-hydroxytryptamine1D receptors: effect of tetrodotoxin, G protein inactivation and long-term antidepressant administration.

Determinants of in vivo activity of neutral endopeptidase 3.4.24.11 and angiotensin converting enzyme inhibitors.

Somatostatin inhibits bombesin-stimulated Gi-protein via its own receptor in rabbit colonic smooth muscle cells.

Pharmacologic characterization of the human 5-hydroxytryptamine2B receptor: evidence for species differences.

Effects of metabolites of leukotriene B4 on human neutrophil migration and cytosolic calcium levels.

Noncompetitive NMDA channel blockade during waking intensely stimulates NREM delta.

Dexamethasone selective inhibition of acute opioid physical dependence in isolated tissues.

Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic-3',5'-guanosine monophosphate-stimulated phosphodiesterase to reverse hypoxic pulmonary vasoconstriction in the perfused rat lung.

Three-day exposure to low-dose ethanol alters guanine nucleotide binding protein expression in the developing rat hippocampus.

Arbutin: mechanism of its depigmenting action in human melanocyte culture.

Galactose-modified streptavidin-GC4 antifibrin monoclonal antibody conjugates: application for two-step thrombus/embolus imaging.

Cannabinoid receptor proteins are increased in Jurkat, human T-cell line after mitogen activation.

Differential coupling of rat D2 dopamine receptor isoforms expressed in Spodoptera frugiperda insect cells.

Effects of single and short-term administration of clonidine on hypothalamic-pituitary somatotropic function of the adult male rat: an in situ hybridization study.

Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression.

Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.

Pharmacological and immunological characterization of N-methyl-D-aspartate receptors in human NT2-N neurons.

Homologous desensitization of thromboxane A2 receptor in 1321N1 human astrocytoma cells.

Sustained activation of phospholipase D via adenosine A3 receptors is associated with enhancement of antigen- and Ca(2+)-ionophore-induced secretion in a rat mast cell line.

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part I: Synaptosomal uptake and tissue concentrations.

Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies.

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