Table of Contents

November 1995; 275 (2)

Select this article
- M Lee,
- K H Yang,
- and N E Kaminski
Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes.
J Pharmacol Exp Ther November 1995 275:529-536
- Abstract
- Full Text (PDF)
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- A Takagi,
- H Masuda,
- Y Takakura,
- and M Hashida
Disposition characteristics of recombinant human interleukin-11 after a bolus intravenous administration in mice.
J Pharmacol Exp Ther November 1995 275:537-543
- Abstract
- Full Text (PDF)
Select this article
- A A Larson and
- K F Kitto
Sensitization to the behavioral effect of kainic acid in the mouse is mediated by nitric oxide.
J Pharmacol Exp Ther November 1995 275:544-550
- Abstract
- Full Text (PDF)
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- H S Kim and
- W K Park
Nitric oxide mediation of cocaine-induced dopaminergic behaviors: ambulation-accelerating activity, reverse tolerance and conditioned place preference in mice.
J Pharmacol Exp Ther November 1995 275:551-557
- Abstract
- Full Text (PDF)
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- T E Jonassen,
- L Grønbeck,
- M Shalmi,
- J S Petersen,
- F Andreasen,
- and S Christensen
Supra-additive natriuretic synergism between bendroflumethiazide and furosemide in rats.
J Pharmacol Exp Ther November 1995 275:558-565
- Abstract
- Full Text (PDF)
Select this article
- D S Sonnichsen,
- Q Liu,
- E G Schuetz,
- J D Schuetz,
- A Pappo,
- and M V Relling
Variability in human cytochrome P450 paclitaxel metabolism.
J Pharmacol Exp Ther November 1995 275:566-575
- Abstract
- Full Text (PDF)
Select this article
- L Zhang and
- X Q Hu
Serotonin stimulates rapid increase of inositol 1,4,5-trisphosphate in ovine uterine artery: correlation with contractile state.
J Pharmacol Exp Ther November 1995 275:576-583
- Abstract
- Full Text (PDF)
Select this article
- G Abou-Mohamed,
- A Papapetropoulos,
- D Ulrich,
- J D Catravas,
- R R Tuttle,
- and R W Caldwell
HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro.
J Pharmacol Exp Ther November 1995 275:584-591
- Abstract
- Full Text (PDF)
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- J Schmider,
- D J Greenblatt,
- L L von Moltke,
- J S Harmatz,
- and R I Shader
N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors.
J Pharmacol Exp Ther November 1995 275:592-597
- Abstract
- Full Text (PDF)
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- C E Tedford,
- S L Yates,
- G P Pawlowski,
- J W Nalwalk,
- L B Hough,
- M A Khan,
- J G Phillips,
- G J Durant,
- and R C Frederickson
Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.
J Pharmacol Exp Ther November 1995 275:598-604
- Abstract
- Full Text (PDF)
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- R B Parker,
- C L Williams,
- S C Laizure,
- and J J Lima
Factors affecting serum protein binding of cocaine in humans.
J Pharmacol Exp Ther November 1995 275:605-610
- Abstract
- Full Text (PDF)
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- P K Rangachari,
- P A Betti,
- E T Prior,
- and L J Roberts, 2nd
Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?
J Pharmacol Exp Ther November 1995 275:611-617
- Abstract
- Full Text (PDF)
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- V Neugebauer,
- G Geisslinger,
- P Rümenapp,
- F Weiretter,
- I Szelenyi,
- K Brune,
- and H G Schaible
Antinociceptive effects of R(-)- and S(+)-flurbiprofen on rat spinal dorsal horn neurons rendered hyperexcitable by an acute knee joint inflammation.
J Pharmacol Exp Ther November 1995 275:618-628
- Abstract
- Full Text (PDF)
Select this article
- F Guirimand,
- M Chauvin,
- J C Willer,
- and D Le Bars
Effects of intrathecal and intracerebroventricular buprenorphine on a C-fiber reflex in the rat.
J Pharmacol Exp Ther November 1995 275:629-637
- Abstract
- Full Text (PDF)
Select this article
- M M Usowicz,
- M Gigg,
- L M Jones,
- C W Cheung,
- and S A Hartley
Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644.
J Pharmacol Exp Ther November 1995 275:638-645
- Abstract
- Full Text (PDF)
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- A A Houdi,
- R T Dowell,
- and J N Diana
Cardiovascular responses to cigarette smoke exposure in restrained conscious rats.
J Pharmacol Exp Ther November 1995 275:646-653
- Abstract
- Full Text (PDF)
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- H J Kim,
- J H Cho,
- and C D Klaassen
Depletion of hepatic 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and sulfate in rats by xenobiotics that are sulfated.
J Pharmacol Exp Ther November 1995 275:654-658
- Abstract
- Full Text (PDF)
Select this article
- L Simon,
- B Ghaleh,
- L Puybasset,
- J F Giudicelli,
- and A Berdeaux
Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs.
J Pharmacol Exp Ther November 1995 275:659-666
- Abstract
- Full Text (PDF)
Select this article
- S Cardin,
- A H Soll,
- and Y Taché
Different effects of indomethacin and nabumetone on prostaglandin-mediated gastric responses to central vagal activation in rats.
J Pharmacol Exp Ther November 1995 275:667-673
- Abstract
- Full Text (PDF)
Select this article
- H Chen,
- H Li,
- and D M Chuang
Role of second messengers in agonist up-regulation of 5-HT2A (5-HT2) receptor binding sites in cerebellar granule neurons: involvement of calcium influx and a calmodulin-dependent pathway.
J Pharmacol Exp Ther November 1995 275:674-680
- Abstract
- Full Text (PDF)
Select this article
- M Gollasch,
- R Bychkov,
- C Ried,
- F Behrendt,
- S Scholze,
- F C Luft,
- and H Haller
Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells.
J Pharmacol Exp Ther November 1995 275:681-692
- Abstract
- Full Text (PDF)
Select this article
- C Rundfeldt,
- P Wlaź,
- D Hönack,
- and W Löscher
Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil.
J Pharmacol Exp Ther November 1995 275:693-702
- Abstract
- Full Text (PDF)
Select this article
- R E Howell,
- L P Jenkins,
- and D E Howell
Inhibition of lipopolysaccharide-induced pulmonary edema by isozyme-selective phosphodiesterase inhibitors in guinea pigs.
J Pharmacol Exp Ther November 1995 275:703-709
- Abstract
- Full Text (PDF)
Select this article
- J Ren,
- E Karpinski,
- and C G Benishin
Prostaglandin E2 contracts vascular smooth muscle and inhibits potassium currents in vascular smooth muscle cells of rat tail artery.
J Pharmacol Exp Ther November 1995 275:710-719
- Abstract
- Full Text (PDF)
Select this article
- D C Deecher,
- O O Odusan,
- and E J Mufson
Galanin receptors in human basal forebrain differ from receptors in the hypothalamus: characterization using [125I]galanin (porcine) and [125I]galantide.
J Pharmacol Exp Ther November 1995 275:720-727
- Abstract
- Full Text (PDF)
Select this article
- M Suzuki,
- T Yamaguchi,
- Y Ozawa,
- M Ohyama,
- and M Yamamoto
Effects of (-)-S-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4,5]decane L-tartrate monohydrate (YM796), a novel muscarinic agonist, on disturbance of passive avoidance learning behavior in drug-treated and senescence-accelerated mice.
J Pharmacol Exp Ther November 1995 275:728-736
- Abstract
- Full Text (PDF)
Select this article
- B D Gitter,
- R F Bruns,
- J J Howbert,
- D C Waters,
- P G Threlkeld,
- L M Cox,
- J A Nixon,
- K L Lobb,
- N R Mason,
- and P W Stengel
Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist.
J Pharmacol Exp Ther November 1995 275:737-744
- Abstract
- Full Text (PDF)
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- N C Trippodo,
- J A Robl,
- M M Asaad,
- J E Bird,
- B C Panchal,
- T R Schaeffer,
- M Fox,
- M R Giancarli,
- and H S Cheung
Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure.
J Pharmacol Exp Ther November 1995 275:745-752
- Abstract
- Full Text (PDF)
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- P Popik,
- R T Layer,
- L H Fossom,
- M Benveniste,
- B Geter-Douglass,
- J M Witkin,
- and P Skolnick
NMDA antagonist properties of the putative antiaddictive drug, ibogaine.
J Pharmacol Exp Ther November 1995 275:753-760
- Abstract
- Full Text (PDF)
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- A H Tang,
- M W Smith,
- D B Carter,
- W B Im,
- and P F VonVoigtlander
U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes.
J Pharmacol Exp Ther November 1995 275:761-767
- Abstract
- Full Text (PDF)
Select this article
- J Liu,
- Y Liu,
- A Parkinson,
- and C D Klaassen
Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice.
J Pharmacol Exp Ther November 1995 275:768-774
- Abstract
- Full Text (PDF)
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- M Asano,
- Y Nomura,
- K Ito,
- Y Uyama,
- Y Imaizumi,
- and M Watanabe
Increased function of voltage-dependent Ca++ channels and Ca(++)-activated K+ channels in resting state of femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
J Pharmacol Exp Ther November 1995 275:775-783
- Abstract
- Full Text (PDF)
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- R Yu and
- M K Ticku
Chronic neurosteroid treatment decreases the efficacy of benzodiazepine ligands and neurosteroids at the gamma-aminobutyric acidA receptor complex in mammalian cortical neurons.
J Pharmacol Exp Ther November 1995 275:784-789
- Abstract
- Full Text (PDF)
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- A J Roberts,
- C N Lessov,
- and T J Phillips
Critical role for glucocorticoid receptors in stress- and ethanol-induced locomotor sensitization.
J Pharmacol Exp Ther November 1995 275:790-797
- Abstract
- Full Text (PDF)
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- P K Gonzalez,
- J Zhuang,
- S R Doctrow,
- B Malfroy,
- P F Benson,
- M J Menconi,
- and M P Fink
EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine.
J Pharmacol Exp Ther November 1995 275:798-806
- Abstract
- Full Text (PDF)
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- Y G Kwak,
- S K Park,
- H S Kang,
- J S Kim,
- S W Chae,
- K P Cho,
- S E Yoo,
- and D Kim
KR-30450, a newly synthesized benzopyran derivative, activates the cardiac ATP-sensitive K+ channel.
J Pharmacol Exp Ther November 1995 275:807-812
- Abstract
- Full Text (PDF)
Select this article
- N Hayase,
- S Inagaki,
- and Y Abiko
Effects of photodegradation products of nifedipine: the nitroso-derivative relaxes contractions of the rat aortic strip induced by norepinephrine and other agonists.
J Pharmacol Exp Ther November 1995 275:813-821
- Abstract
- Full Text (PDF)
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- R Schreiber,
- M Brocco,
- B Lefèbvre de Ladonchamps,
- S Monneyron,
- and M J Millan
A drug discrimination analysis of the actions of novel serotonin1A receptor ligands in the rat using the 5-HT1A receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin.
J Pharmacol Exp Ther November 1995 275:822-831
- Abstract
- Full Text (PDF)
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- M Kähönen,
- P A Doris,
- H Mäkynen,
- and I Pörsti
Plasma digoxin immunoreactivity and arterial potassium relaxation after quinapril therapy in hypertensive rats.
J Pharmacol Exp Ther November 1995 275:832-837
- Abstract
- Full Text (PDF)
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- D M Mooney,
- B Hu,
- and V V Senatorov
Muscarine induces an anomalous inhibition of synaptic transmission in rat auditory thalamic neurons in vitro.
J Pharmacol Exp Ther November 1995 275:838-844
- Abstract
- Full Text (PDF)
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- L Steardo,
- P Monteleone,
- M d'Istria,
- I Serino,
- M Maj,
- and V Cuomo
(+)-N-allylnormetazocine enhances N-acetyltransferase activity and melatonin synthesis: preliminary evidence for a functional role of sigma receptors in the rat pineal gland.
J Pharmacol Exp Ther November 1995 275:845-849
- Abstract
- Full Text (PDF)
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- F Buttgereit,
- I Brink,
- B Thiele,
- G R Burmester,
- F Hiepe,
- and E D Hall
Effects of methylprednisolone and 21-aminosteroids on mitogen-induced interleukin-6 and tumor necrosis factor-alpha production in human peripheral blood mononuclear cells.
J Pharmacol Exp Ther November 1995 275:850-853
- Abstract
- Full Text (PDF)
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- O Edling,
- G Bao,
- M Feelisch,
- T Unger,
- and P Gohlke
Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril.
J Pharmacol Exp Ther November 1995 275:854-863
- Abstract
- Full Text (PDF)
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- R Bouchard and
- D Fedida
Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5.
J Pharmacol Exp Ther November 1995 275:864-876
- Abstract
- Full Text (PDF)
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- J Wang and
- K M Johnson
Regulation of striatal cyclic-3',5'-adenosine monophosphate accumulation and GABA release by glutamate metabotropic and dopamine D1 receptors.
J Pharmacol Exp Ther November 1995 275:877-884
- Abstract
- Full Text (PDF)
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- M J Millan,
- J L Peglion,
- J Vian,
- J M Rivet,
- M Brocco,
- A Gobert,
- A Newman-Tancredi,
- C Dacquet,
- K Bervoets,
- and S Girardon
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy.
J Pharmacol Exp Ther November 1995 275:885-898
- Abstract
- Full Text (PDF)
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- A Gobert,
- J M Rivet,
- V Audinot,
- L Cistarelli,
- M Spedding,
- J Vian,
- J L Peglion,
- and M J Millan
Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways.
J Pharmacol Exp Ther November 1995 275:899-913
- Abstract
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- C Casati,
- A Monopoli,
- A Forlani,
- E Bonizzoni,
- and E Ongini
Telemetry monitoring of hemodynamic effects induced over time by adenosine agonists in spontaneously hypertensive rats.
J Pharmacol Exp Ther November 1995 275:914-919
- Abstract
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- K Ito,
- K Ito,
- Y Sawada,
- J Kamei,
- M Misawa,
- and T Iga
Toxicodynamic analysis of cough and inflammatory reactions by angiotensin-converting enzyme inhibitors in guinea pig.
J Pharmacol Exp Ther November 1995 275:920-925
- Abstract
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- C E Groves,
- M N Morales,
- A J Gandolfi,
- W H Dantzler,
- and S H Wright
Peritubular paraquat transport in isolated renal proximal tubules.
J Pharmacol Exp Ther November 1995 275:926-932
- Abstract
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- C Chou,
- A J McLachlan,
- and M Rowland
Membrane permeability and lipophilicity in the isolated perfused rat liver: 5-ethyl barbituric acid and other compounds.
J Pharmacol Exp Ther November 1995 275:933-940
- Abstract
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- C F Toombs,
- G L DeGraaf,
- J P Martin,
- J G Geng,
- D C Anderson,
- and R J Shebuski
Pretreatment with a blocking monoclonal antibody to P-selectin accelerates pharmacological thrombolysis in a primate model of arterial thrombosis.
J Pharmacol Exp Ther November 1995 275:941-949
- Abstract
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- Y C Han and
- S B Pruett
Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking.
J Pharmacol Exp Ther November 1995 275:950-957
- Abstract
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- T Lindmark,
- T Nikkilä,
- and P Artursson
Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers.
J Pharmacol Exp Ther November 1995 275:958-964
- Abstract
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- R A Dean,
- J Zhang,
- M R Brzezinski,
- and W F Bosron
Tissue distribution of cocaine methyl esterase and ethyl transferase activities: correlation with carboxylesterase protein.
J Pharmacol Exp Ther November 1995 275:965-971
- Abstract
- Full Text (PDF)
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- M Shimada,
- N Murayama,
- Y Yamazoe,
- H Hashimoto,
- H Ishikawa,
- and R Kato
Age- and sex-related alterations of microsomal drug- and testosterone-oxidizing cytochrome P450 in Sprague-Dawley strain-derived dwarf rats.
J Pharmacol Exp Ther November 1995 275:972-977
- Abstract
- Full Text (PDF)
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- E E Daniel,
- V Gaspar,
- I Berezin,
- and C Y Kwan
Characterization of alpha 2 adrenoceptors and other adrenoceptors in membranes isolated from dog mesenteric nerve axons.
J Pharmacol Exp Ther November 1995 275:978-986
- Abstract
- Full Text (PDF)
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- M Bencherif,
- K Fowler,
- R J Lukas,
- and P M Lippiello
Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain.
J Pharmacol Exp Ther November 1995 275:987-994
- Abstract
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- P B Jacobson,
- S L Kuchera,
- A Metz,
- C Schächtele,
- K Imre,
- and D J Schrier
Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.
J Pharmacol Exp Ther November 1995 275:995-1002
- Abstract
- Full Text (PDF)
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- M J Picklo,
- R G Wiley,
- S Lonce,
- D A Lappi,
- and D Robertson
Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats.
J Pharmacol Exp Ther November 1995 275:1003-1010
- Abstract
- Full Text (PDF)
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- E G Schuetz,
- K N Furuya,
- and J D Schuetz
Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.
J Pharmacol Exp Ther November 1995 275:1011-1018
- Abstract
- Full Text (PDF)
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- R C Pierce and
- P W Kalivas
Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.
J Pharmacol Exp Ther November 1995 275:1019-1029
- Abstract
- Full Text (PDF)
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- D C Perry and
- K J Kellar
[3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study.
J Pharmacol Exp Ther November 1995 275:1030-1034
- Abstract
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- M A Scofield,
- F Liu,
- P W Abel,
- and W B Jeffries
Quantification of steady state expression of mRNA for alpha-1 adrenergic receptor subtypes using reverse transcription and a competitive polymerase chain reaction.
J Pharmacol Exp Ther November 1995 275:1035-1042
- Abstract
- Full Text (PDF)
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- H M Cherwinski,
- R G Cohn,
- P Cheung,
- D J Webster,
- Y Z Xu,
- J P Caulfield,
- J M Young,
- G Nakano,
- and J T Ransom
The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.
J Pharmacol Exp Ther November 1995 275:1043-1049
- Abstract
- Full Text (PDF)
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- R L Smith,
- R J Barrett,
- and E Sanders-Bush
Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor.
J Pharmacol Exp Ther November 1995 275:1050-1057
- Abstract
- Full Text (PDF)
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- L W Liu,
- L Thuneberg,
- and J D Huizinga
Cyclopiazonic acid, inhibiting the endoplasmic reticulum calcium pump, reduces the canine colonic pacemaker frequency.
J Pharmacol Exp Ther November 1995 275:1058-1068
- Abstract
- Full Text (PDF)
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- M Visentin,
- R Bellasio,
- and M T Tacconi
Reye syndrome model in rats: protection against liver abnormalities by L-carnitine and acetyl-L-carnitine.
J Pharmacol Exp Ther November 1995 275:1069-1075
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes.

Disposition characteristics of recombinant human interleukin-11 after a bolus intravenous administration in mice.

Sensitization to the behavioral effect of kainic acid in the mouse is mediated by nitric oxide.

Nitric oxide mediation of cocaine-induced dopaminergic behaviors: ambulation-accelerating activity, reverse tolerance and conditioned place preference in mice.

Supra-additive natriuretic synergism between bendroflumethiazide and furosemide in rats.

Variability in human cytochrome P450 paclitaxel metabolism.

Serotonin stimulates rapid increase of inositol 1,4,5-trisphosphate in ovine uterine artery: correlation with contractile state.

HP-228, a novel synthetic peptide, inhibits the induction of nitric oxide synthase in vivo but not in vitro.

N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors.

Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.

Factors affecting serum protein binding of cocaine in humans.

Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: an argument for a different DP receptor?

Antinociceptive effects of R(-)- and S(+)-flurbiprofen on rat spinal dorsal horn neurons rendered hyperexcitable by an acute knee joint inflammation.

Effects of intrathecal and intracerebroventricular buprenorphine on a C-fiber reflex in the rat.

Allosteric interactions at L-type calcium channels between FPL 64176 and the enantiomers of the dihydropyridine Bay K 8644.

Cardiovascular responses to cigarette smoke exposure in restrained conscious rats.

Depletion of hepatic 3'-phosphoadenosine 5'-phosphosulfate (PAPS) and sulfate in rats by xenobiotics that are sulfated.

Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs.

Different effects of indomethacin and nabumetone on prostaglandin-mediated gastric responses to central vagal activation in rats.

Role of second messengers in agonist up-regulation of 5-HT2A (5-HT2) receptor binding sites in cerebellar granule neurons: involvement of calcium influx and a calmodulin-dependent pathway.

Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells.

Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil.

Inhibition of lipopolysaccharide-induced pulmonary edema by isozyme-selective phosphodiesterase inhibitors in guinea pigs.

Prostaglandin E2 contracts vascular smooth muscle and inhibits potassium currents in vascular smooth muscle cells of rat tail artery.

Galanin receptors in human basal forebrain differ from receptors in the hypothalamus: characterization using [125I]galanin (porcine) and [125I]galantide.

Effects of (-)-S-2,8-dimethyl-3-methylene-1-oxa-8-azaspiro[4,5]decane L-tartrate monohydrate (YM796), a novel muscarinic agonist, on disturbance of passive avoidance learning behavior in drug-treated and senescence-accelerated mice.

Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist.

Cardiovascular effects of the novel dual inhibitor of neutral endopeptidase and angiotensin-converting enzyme BMS-182657 in experimental hypertension and heart failure.

NMDA antagonist properties of the putative antiaddictive drug, ibogaine.

U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes.

Effect of oleanolic acid on hepatic toxicant-activating and detoxifying systems in mice.

Increased function of voltage-dependent Ca++ channels and Ca(++)-activated K+ channels in resting state of femoral arteries from spontaneously hypertensive rats at prehypertensive stage.

Chronic neurosteroid treatment decreases the efficacy of benzodiazepine ligands and neurosteroids at the gamma-aminobutyric acidA receptor complex in mammalian cortical neurons.

Critical role for glucocorticoid receptors in stress- and ethanol-induced locomotor sensitization.

EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine.

KR-30450, a newly synthesized benzopyran derivative, activates the cardiac ATP-sensitive K+ channel.

Effects of photodegradation products of nifedipine: the nitroso-derivative relaxes contractions of the rat aortic strip induced by norepinephrine and other agonists.

A drug discrimination analysis of the actions of novel serotonin1A receptor ligands in the rat using the 5-HT1A receptor agonist, 8-hydroxy-2-(di-n-propylamino)tetralin.

Plasma digoxin immunoreactivity and arterial potassium relaxation after quinapril therapy in hypertensive rats.

Muscarine induces an anomalous inhibition of synaptic transmission in rat auditory thalamic neurons in vitro.

(+)-N-allylnormetazocine enhances N-acetyltransferase activity and melatonin synthesis: preliminary evidence for a functional role of sigma receptors in the rat pineal gland.

Effects of methylprednisolone and 21-aminosteroids on mitogen-induced interleukin-6 and tumor necrosis factor-alpha production in human peripheral blood mononuclear cells.

Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril.

Closed- and open-state binding of 4-aminopyridine to the cloned human potassium channel Kv1.5.

Regulation of striatal cyclic-3',5'-adenosine monophosphate accumulation and GABA release by glutamate metabotropic and dopamine D1 receptors.

Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy.

Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: II. Both D2 and "silent" D3 autoreceptors control synthesis and release in mesolimbic, mesocortical and nigrostriatal pathways.

Telemetry monitoring of hemodynamic effects induced over time by adenosine agonists in spontaneously hypertensive rats.

Toxicodynamic analysis of cough and inflammatory reactions by angiotensin-converting enzyme inhibitors in guinea pig.

Peritubular paraquat transport in isolated renal proximal tubules.

Membrane permeability and lipophilicity in the isolated perfused rat liver: 5-ethyl barbituric acid and other compounds.

Pretreatment with a blocking monoclonal antibody to P-selectin accelerates pharmacological thrombolysis in a primate model of arterial thrombosis.

Mechanisms of ethanol-induced suppression of a primary antibody response in a mouse model for binge drinking.

Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers.

Tissue distribution of cocaine methyl esterase and ethyl transferase activities: correlation with carboxylesterase protein.

Age- and sex-related alterations of microsomal drug- and testosterone-oxidizing cytochrome P450 in Sprague-Dawley strain-derived dwarf rats.

Characterization of alpha 2 adrenoceptors and other adrenoceptors in membranes isolated from dog mesenteric nerve axons.

Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain.

Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.

Anti-dopamine beta-hydroxylase immunotoxin-induced sympathectomy in adult rats.

Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.

Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine.

[3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study.

Quantification of steady state expression of mRNA for alpha-1 adrenergic receptor subtypes using reverse transcription and a competitive polymerase chain reaction.

The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis.

Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor.

Cyclopiazonic acid, inhibiting the endoplasmic reticulum calcium pump, reduces the canine colonic pacemaker frequency.

Reye syndrome model in rats: protection against liver abnormalities by L-carnitine and acetyl-L-carnitine.

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