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Table of Contents
July 1995; 274 (1)
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M L Pucci
,
L B Dick
,
K B Miller
,
C J Smith
,
and
A Nasjletti
Enhanced responses to L-arginine in aortic rings from rats with angiotensin-dependent hypertension.
J Pharmacol Exp Ther
July 1995
274
:
1
-
7
Abstract
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J Y Xu
and
L F Tseng
Nitric oxide/cyclic guanosine monophosphate system in the spinal cord differentially modulates intracerebroventricularly administered morphine- and beta-endorphin-induced antinociception in the mouse.
J Pharmacol Exp Ther
July 1995
274
:
8
-
16
Abstract
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C P France
,
L R Gerak
,
D Flynn
,
G D Winger
,
F Medzihradsky
,
J R Bagley
,
L L Brockunier
,
and
J H Woods
Behavioral effects and receptor binding affinities of fentanyl derivatives in rhesus monkeys.
J Pharmacol Exp Ther
July 1995
274
:
17
-
28
Abstract
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D M Ford
,
R E Thieme
,
C A Lamp
,
S J Covington
,
and
B A Molitoris
HWA-448 reduces gentamicin toxicity in LLC-PK1 cells.
J Pharmacol Exp Ther
July 1995
274
:
29
-
33
Abstract
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H M Amin
,
A M Sopchak
,
B F Esposito
,
L G Henson
,
R L Batenhorst
,
A W Fox
,
and
E M Camporesi
Naloxone-induced and spontaneous reversal of depressed ventilatory responses to hypoxia during and after continuous infusion of remifentanil or alfentanil.
J Pharmacol Exp Ther
July 1995
274
:
34
-
39
Abstract
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I Nakae
,
M Takahashi
,
T Kinoshita
,
T Matsumoto
,
and
M Kinoshita
The effects of S-nitrosocaptopril on canine coronary circulation.
J Pharmacol Exp Ther
July 1995
274
:
40
-
46
Abstract
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G C Wellman
and
J A Bevan
Barium inhibits the endothelium-dependent component of flow but not acetylcholine-induced relaxation in isolated rabbit cerebral arteries.
J Pharmacol Exp Ther
July 1995
274
:
47
-
53
Abstract
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L Lacinová
,
A Welling
,
E Bosse
,
P Ruth
,
V Flockerzi
,
and
F Hofmann
Interaction of Ro 40-5967 and verapamil with the stably expressed alpha 1-subunit of the cardiac L-type calcium channel.
J Pharmacol Exp Ther
July 1995
274
:
54
-
63
Abstract
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V Ralevic
,
P Karoon
,
and
G Burnstock
Long-term sensory denervation by neonatal capsaicin treatment augments sympathetic neurotransmission in rat mesenteric arteries by increasing levels of norepinephrine and selectively enhancing postjunctional actions.
J Pharmacol Exp Ther
July 1995
274
:
64
-
71
Abstract
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J M Goldhill
,
F D Finkelman
,
S C Morris
,
and
T Shea-Donohue
Neural control of mouse small intestinal longitudinal muscle: interactions with inflammatory mediators.
J Pharmacol Exp Ther
July 1995
274
:
72
-
77
Abstract
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R R Nadeau
,
C Ostrowski
,
G Ni-Wu
,
and
D J Liberato
Pharmacokinetics and pharmacodynamics of recombinant human interleukin-12 in male rhesus monkeys.
J Pharmacol Exp Ther
July 1995
274
:
78
-
83
Abstract
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C C Tenn
and
L P Niles
Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism.
J Pharmacol Exp Ther
July 1995
274
:
84
-
89
Abstract
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W P Melega
,
A E Williams
,
D A Schmitz
,
E W DiStefano
,
and
A K Cho
Pharmacokinetic and pharmacodynamic analysis of the actions of D-amphetamine and D-methamphetamine on the dopamine terminal.
J Pharmacol Exp Ther
July 1995
274
:
90
-
96
Abstract
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S M Knepper
,
S A Buckner
,
M E Brune
,
J F DeBernardis
,
M D Meyer
,
and
A A Hancock
A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype.
J Pharmacol Exp Ther
July 1995
274
:
97
-
103
Abstract
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S N Tüzel-Kox
,
H M Patel
,
and
W J Kox
Uptake of drug-carrier liposomes by placenta: transplacental delivery of drugs and nutrients.
J Pharmacol Exp Ther
July 1995
274
:
104
-
109
Abstract
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C B Washington
,
C M Brett
,
X Wu
,
and
K M Giacomini
The effect of N-ethylmaleimide on the Na(+)-dependent nucleoside transporter (N3) in rabbit choroid plexus.
J Pharmacol Exp Ther
July 1995
274
:
110
-
114
Abstract
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E Kuhls
,
I S Gauntlett
,
M Lau
,
R Brown
,
C D Rudolph
,
D F Teitel
,
and
D M Fisher
Effect of increased intra-abdominal pressure on hepatic extraction and clearance of fentanyl in neonatal lambs.
J Pharmacol Exp Ther
July 1995
274
:
115
-
119
Abstract
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A Sanbe
and
S Takeo
Effects of NKH477, a water-soluble forskolin derivative, on cardiac function in rats with chronic heart failure after myocardial infarction.
J Pharmacol Exp Ther
July 1995
274
:
120
-
126
Abstract
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A Pap
and
C W Bradberry
Excitatory amino acid antagonists attenuate the effects of cocaine on extracellular dopamine in the nucleus accumbens.
J Pharmacol Exp Ther
July 1995
274
:
127
-
133
Abstract
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N T Burford
,
A B Tobin
,
and
S R Nahorski
Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells.
J Pharmacol Exp Ther
July 1995
274
:
134
-
142
Abstract
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K Groen
,
D D Breimer
,
A Brouwer
,
G Schijff
,
E J Jansen
,
and
C F van Bezooijen
The influence of dietary restriction on the metabolism of theophylline and antipyrine in the ageing female BN/BiRij rat.
J Pharmacol Exp Ther
July 1995
274
:
143
-
147
Abstract
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F Oury-Donat
,
P Carayon
,
O Thurneyssen
,
V Pailhon
,
X Emonds-Alt
,
P Soubrié
,
and
G Le Fur
Functional characterization of the nonpeptide neurokinin3 (NK3) receptor antagonist, SR142801 on the human NK3 receptor expressed in Chinese hamster ovary cells.
J Pharmacol Exp Ther
July 1995
274
:
148
-
154
Abstract
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M Mortensen
,
P D Suzdak
,
and
C Thomsen
The effect of lorazepam tolerance and withdrawal on metabotropic glutamate receptor function.
J Pharmacol Exp Ther
July 1995
274
:
155
-
163
Abstract
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D M Lovinger
Developmental decrease in ethanol inhibition of N-methyl-D-aspartate receptors in rat neocortical neurons: relation to the actions of ifenprodil.
J Pharmacol Exp Ther
July 1995
274
:
164
-
172
Abstract
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A Bourson
,
E Borroni
,
R H Austin
,
F J Monsma, Jr
,
and
A J Sleight
Determination of the role of the 5-ht6 receptor in the rat brain: a study using antisense oligonucleotides.
J Pharmacol Exp Ther
July 1995
274
:
173
-
180
Abstract
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S M Aziz
,
M P Gosland
,
P A Crooks
,
J W Olson
,
and
M N Gillespie
A novel polymeric spermine conjugate inhibits polyamine transport in pulmonary artery smooth muscle cells.
J Pharmacol Exp Ther
July 1995
274
:
181
-
186
Abstract
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N Sugihara
,
T Suetsugu
,
and
K Furuno
High susceptibility to paraquat-driven lipid peroxidation of cultured hepatocytes loaded with linolenic acid.
J Pharmacol Exp Ther
July 1995
274
:
187
-
193
Abstract
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B M Tune
and
C Y Hsu
Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates.
J Pharmacol Exp Ther
July 1995
274
:
194
-
199
Abstract
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E A Konorev
,
M M Tarpey
,
J Joseph
,
J E Baker
,
and
B Kalyanaraman
S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest-evidence for a cardioprotective effect of nitric oxide.
J Pharmacol Exp Ther
July 1995
274
:
200
-
206
Abstract
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B E Garrett
and
S G Holtzman
Does adenosine receptor blockade mediate caffeine-induced rotational behavior?
J Pharmacol Exp Ther
July 1995
274
:
207
-
214
Abstract
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E F McCance
,
L H Price
,
T R Kosten
,
and
P I Jatlow
Cocaethylene: pharmacology, physiology and behavioral effects in humans.
J Pharmacol Exp Ther
July 1995
274
:
215
-
223
Abstract
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A I Sacaan
,
J L Dunlop
,
and
G K Lloyd
Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices.
J Pharmacol Exp Ther
July 1995
274
:
224
-
230
Abstract
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S M Florin
,
R Kuczenski
,
and
D S Segal
Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations.
J Pharmacol Exp Ther
July 1995
274
:
231
-
241
Abstract
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A Camins
,
E Escubedo
,
J Camarasa
,
J Carretero
,
A H Newman
,
and
M E Kammüller
Dog neutrophil stimulation and cell surface expression of heat shock proteins induced by AHN 086.
J Pharmacol Exp Ther
July 1995
274
:
242
-
248
Abstract
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Z H Zhang
and
M I Steinberg
LY 97241 accelerates the apparent rate of inactivation of transient outward K+ current: characterization of open channel block.
J Pharmacol Exp Ther
July 1995
274
:
249
-
257
Abstract
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J H Todd
and
G H Hottendorf
Renal brush border membrane vesicle aminoglycoside binding and nephrotoxicity.
J Pharmacol Exp Ther
July 1995
274
:
258
-
263
Abstract
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J H Lin
,
M Chiba
,
I W Chen
,
K J Vastag
,
J A Nishime
,
B D Dorsey
,
S R Michelson
,
and
S L McDaniel
Time- and dose-dependent pharmacokinetics of L-754,394, an HIV protease inhibitor, in rats, dogs and monkeys.
J Pharmacol Exp Ther
July 1995
274
:
264
-
269
Abstract
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T K Chang
,
G Chen
,
and
D J Waxman
Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism.
J Pharmacol Exp Ther
July 1995
274
:
270
-
275
Abstract
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A J Eshleman
,
R L Neve
,
A Janowsky
,
and
K A Neve
Characterization of a recombinant human dopamine transporter in multiple cell lines.
J Pharmacol Exp Ther
July 1995
274
:
276
-
283
Abstract
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C M Handler
,
D J Mondgock
,
S F Zhao
,
E B Geller
,
and
M W Adler
Interaction between opioid agonists and neurotensin on thermoregulation in the rat. I. Body temperature.
J Pharmacol Exp Ther
July 1995
274
:
284
-
292
Abstract
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N F Jensen
and
T D Egan
Defining the concentration-effect relationship of volatile anesthetics in vessels using an in vitro nonsteady-state technique.
J Pharmacol Exp Ther
July 1995
274
:
293
-
299
Abstract
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K S Murthy
,
L McHenry
,
J R Grider
,
and
G M Makhlouf
Adenosine A1 and A2b receptors coupled to distinct interactive signaling pathways in intestinal muscle cells.
J Pharmacol Exp Ther
July 1995
274
:
300
-
306
Abstract
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W Löscher
and
D Hönack
Anticonvulsant and antiepileptogenic effect of L-deprenyl (selegiline) in the kindling model of epilepsy.
J Pharmacol Exp Ther
July 1995
274
:
307
-
314
Abstract
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T Yamashita
,
T Nakajima
,
E Hamada
,
H Hazama
,
M Omata
,
and
Y Kurachi
Flecainide inhibits the transient outward current in atrial myocytes isolated from the rabbit heart.
J Pharmacol Exp Ther
July 1995
274
:
315
-
321
Abstract
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P Holzer
,
W Schluet
,
and
C A Maggi
Substance P stimulates and inhibits intestinal peristalsis via distinct receptors.
J Pharmacol Exp Ther
July 1995
274
:
322
-
328
Abstract
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T Kikuchi
,
K Tottori
,
Y Uwahodo
,
T Hirose
,
T Miwa
,
Y Oshiro
,
and
S Morita
7-(4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyloxy)-3,4-dihydro-2(1H)-quinolinone (OPC-14597), a new putative antipsychotic drug with both presynaptic dopamine autoreceptor agonistic activity and postsynaptic D2 receptor antagonistic activity.
J Pharmacol Exp Ther
July 1995
274
:
329
-
336
Abstract
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Y Odagaki
and
K Fuxe
Pharmacological characterization of the 5-hydroxytryptamine-1A receptor-mediated activation of high-affinity GTP hydrolysis in rat hippocampal membranes.
J Pharmacol Exp Ther
July 1995
274
:
337
-
344
Abstract
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L J Brunner
,
J T DiPiro
,
and
S Feldman
Antipyrine pharmacokinetics in the tail-suspended rat model.
J Pharmacol Exp Ther
July 1995
274
:
345
-
352
Abstract
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E Sanna
,
M P Mascia
,
R L Klein
,
P J Whiting
,
G Biggio
,
and
R A Harris
Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits.
J Pharmacol Exp Ther
July 1995
274
:
353
-
360
Abstract
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S L Walsh
,
K L Preston
,
G E Bigelow
,
and
M L Stitzer
Acute administration of buprenorphine in humans: partial agonist and blockade effects.
J Pharmacol Exp Ther
July 1995
274
:
361
-
372
Abstract
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Y Taki
,
T Sakane
,
T Nadai
,
H Sezaki
,
G L Amidon
,
P Langguth
,
and
S Yamashita
Gastrointestinal absorption of peptide drug: quantitative evaluation of the degradation and the permeation of metkephamid in rat small intestine.
J Pharmacol Exp Ther
July 1995
274
:
373
-
377
Abstract
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G Z Dong
,
K Kameyama
,
A Rinken
,
and
T Haga
Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells.
J Pharmacol Exp Ther
July 1995
274
:
378
-
384
Abstract
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R B Rothman
,
M L Silverthorn
,
M H Baumann
,
C B Goodman
,
J L Cadet
,
D Matecka
,
K C Rice
,
F I Carroll
,
J B Wang
,
and
G R Uhl
Studies of the biogenic amine transporters. VI. Characterization of a novel cocaine binding site, identified with [125I]RTI-55, in membranes prepared from whole rat brain minus caudate.
J Pharmacol Exp Ther
July 1995
274
:
385
-
395
Abstract
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S R Jones
,
P A Garris
,
and
R M Wightman
Different effects of cocaine and nomifensine on dopamine uptake in the caudate-putamen and nucleus accumbens.
J Pharmacol Exp Ther
July 1995
274
:
396
-
403
Abstract
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J M Rhoads
,
R A Argenzio
,
W Chen
,
and
G G Gomez
Asparagine stimulates piglet intestinal Cl- secretion by a mechanism requiring a submucosal glutamate receptor and nitric oxide.
J Pharmacol Exp Ther
July 1995
274
:
404
-
412
Abstract
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S Hoshida
,
N Yamashita
,
J Igarashi
,
M Nishida
,
M Hori
,
T Kamada
,
T Kuzuya
,
and
M Tada
Nitric oxide synthase protects the heart against ischemia-reperfusion injury in rabbits.
J Pharmacol Exp Ther
July 1995
274
:
413
-
418
Abstract
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J Sun
and
D J Triggle
Calcium channel antagonists: cardiovascular selectivity of action.
J Pharmacol Exp Ther
July 1995
274
:
419
-
426
Abstract
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A M Mayer
,
S Brenic
,
R Stocker
,
and
K B Glaser
Modulation of superoxide generation in in vivo lipopolysaccharide-primed rat alveolar macrophages by arachidonic acid and inhibitors of protein kinase C, phospholipase A2, protein serine-threonine phosphatase(s), protein tyrosine kinase(s) and phosphatase(s).
J Pharmacol Exp Ther
July 1995
274
:
427
-
436
Abstract
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L Ratnakumari
,
I A Qureshi
,
D Maysinger
,
and
R F Butterworth
Developmental deficiency of the cholinergic system in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine.
J Pharmacol Exp Ther
July 1995
274
:
437
-
443
Abstract
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D Rampe
,
Z Wang
,
B Fermini
,
B Wible
,
R C Dage
,
and
S Nattel
Voltage- and time-dependent block by perhexiline of K+ currents in human atrium and in cells expressing a Kv1.5-type cloned channel.
J Pharmacol Exp Ther
July 1995
274
:
444
-
449
Abstract
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M Sala
,
D Braida
,
M Colombo
,
A Groppetti
,
S Sacco
,
E Gori
,
and
M Parenti
Behavioral and biochemical evidence of opioidergic involvement in cocaine sensitization.
J Pharmacol Exp Ther
July 1995
274
:
450
-
457
Abstract
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P Alberts
Classification of the presynaptic muscarinic receptor subtype that regulates 3H-acetylcholine secretion in the guinea pig urinary bladder in vitro.
J Pharmacol Exp Ther
July 1995
274
:
458
-
468
Abstract
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R Sato
,
S Koumi
,
I Hisatome
,
H Takai
,
Y Aida
,
M Oyaizu
,
S Karasaki
,
H Mashiba
,
and
R Katori
A new class III antiarrhythmic drug, MS-551, blocks the inward rectifier potassium channel in isolated guinea pig ventricular myocytes.
J Pharmacol Exp Ther
July 1995
274
:
469
-
474
Abstract
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P Y Wong
,
G Yue
,
K Yin
,
M Miyasaka
,
C L Lane
,
A M Manning
,
D C Anderson
,
and
F F Sun
Antibodies to intercellular adhesion molecule-1 ameliorate the inflammatory response in acetic acid-induced inflammatory bowel disease.
J Pharmacol Exp Ther
July 1995
274
:
475
-
480
Abstract
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H Karam
,
P Bruneval
,
J P Clozel
,
B M Löffler
,
J Bariéty
,
and
M Clozel
Role of endothelin in acute renal failure due to rhabdomyolysis in rats.
J Pharmacol Exp Ther
July 1995
274
:
481
-
486
Abstract
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T Kanda
,
H Nagaoka
,
K Kaneko
,
J E Wilson
,
B M McManus
,
S Imai
,
T Suzuki
,
K Murata
,
and
I Kobayashi
Synergistic effects of tacrolimus and human interferon-alpha A/D in murine viral myocarditis.
J Pharmacol Exp Ther
July 1995
274
:
487
-
493
Abstract
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T Kanda
,
T Yokoyama
,
S Imai
,
T Suzuki
,
K Murata
,
and
I Kobayashi
Effect of combination therapy with OK432 and recombinant human interferon-alpha A/D on atrial natriuretic peptide gene expression in mice with viral myocarditis.
J Pharmacol Exp Ther
July 1995
274
:
494
-
498
Abstract
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J R Wu-Wong
,
W J Chiou
,
S R Magnuson
,
and
T J Opgenorth
Endothelin receptor in human astrocytoma U373MG cells: binding, dissociation, receptor internalization.
J Pharmacol Exp Ther
July 1995
274
:
499
-
507
Abstract
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H J Duff
,
M Stemler
,
T Thannhauser
,
S Laganiere
,
E Rude
,
and
W Lester
Proarrhythmia of a class Ic drug: suppression by combination with a drug prolonging repolarization in the dog late after infarction.
J Pharmacol Exp Ther
July 1995
274
:
508
-
515
Abstract
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M L Dahl
,
I Johansson
,
L Bertilsson
,
M Ingelman-Sundberg
,
and
F Sjöqvist
Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis.
J Pharmacol Exp Ther
July 1995
274
:
516
-
520
Abstract
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J Y Wang
,
S A McCormack
,
M J Viar
,
and
L R Johnson
Inhibition of ornithine decarboxylase activity but not expression of the gene by cimetidine in intestinal mucosal cells.
J Pharmacol Exp Ther
July 1995
274
:
521
-
529
Abstract
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J Neumann
,
S Herzig
,
P Boknik
,
M Apel
,
G Kaspareit
,
W Schmitz
,
H Scholz
,
M Tepel
,
and
N Zimmermann
On the cardiac contractile, biochemical and electrophysiological effects of cantharidin, a phosphatase inhibitor.
J Pharmacol Exp Ther
July 1995
274
:
530
-
539
Abstract
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D C McMillan
,
J V Simson
,
R A Budinsky
,
and
D J Jollow
Dapsone-induced hemolytic anemia: effect of dapsone hydroxylamine on sulfhydryl status, membrane skeletal proteins and morphology of human and rat erythrocytes.
J Pharmacol Exp Ther
July 1995
274
:
540
-
547
Abstract
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D S Fletcher
,
D G Osinga
,
K Keenan
,
R J Bonney
,
J B Doherty
,
P E Finke
,
S K Shah
,
and
P Davies
An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.
J Pharmacol Exp Ther
July 1995
274
:
548
-
554
Abstract
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A Fujita
,
T Takeuchi
,
H Nakajima
,
H Nishio
,
and
F Hata
Involvement of heterotrimeric GTP-binding protein and rho protein, but not protein kinase C, in agonist-induced Ca2+ sensitization of skinned muscle of guinea pig vas deferens.
J Pharmacol Exp Ther
July 1995
274
:
555
-
561
Abstract
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K L Dopke
,
K E Vrana
,
L J Vogt
,
and
B A Vogt
AF-DX 384 binding in rabbit cingulate cortex: two site kinetics and section autoradiography.
J Pharmacol Exp Ther
July 1995
274
:
562
-
569
Abstract
Full Text (PDF)
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M L Donadoni
,
R Gavezzotti
,
F Borella
,
A M Di Giulio
,
and
A Gorio
Experimental diabetic neuropathy. Inhibition of protein mono-ADP-ribosylation prevents reduction of substance P axonal transport.
J Pharmacol Exp Ther
July 1995
274
:
570
-
576
Abstract
Full Text (PDF)
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M Allard
,
S Labrouche
,
A Nosjean
,
and
R Laguzzi
Mechanisms underlying the cardiovascular responses to peripheral administration of NPFF in the rat.
J Pharmacol Exp Ther
July 1995
274
:
577
-
583
Abstract
Full Text (PDF)
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H Takemura
,
J Tamaoki
,
E Tagaya
,
A Chiyotani
,
and
K Konno
Isoproterenol increases Cl diffusion potential difference of rabbit trachea through nitric oxide generation.
J Pharmacol Exp Ther
July 1995
274
:
584
-
588
Abstract
Full Text (PDF)
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July 1995; 274 (1)
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