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Table of Contents
April 1995; 273 (1)
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T Kitazono
,
D D Heistad
,
and
F M Faraci
Dilatation of the basilar artery in response to selective activation of endothelin B receptors in vivo.
J Pharmacol Exp Ther
April 1995
273
:
1
-
6
Abstract
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E Tirelli
and
J M Witkin
Differential effects of direct and indirect dopamine agonists on the induction of gnawing in C57Bl/6J mice.
J Pharmacol Exp Ther
April 1995
273
:
7
-
15
Abstract
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M J Patel
,
D M Wypij
,
D A Rose
,
T J Rimele
,
and
J S Wiseman
Secretion of cyclic GMP by cultured epithelial and fibroblast cell lines in response to nitric oxide.
J Pharmacol Exp Ther
April 1995
273
:
16
-
25
Abstract
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I Tamai
,
N Tomizawa
,
T Takeuchi
,
K Nakayama
,
H Higashida
,
and
A Tsuji
Functional expression of transporter for beta-lactam antibiotics and dipeptides in Xenopus laevis oocytes injected with messenger RNA from human, rat and rabbit small intestines.
J Pharmacol Exp Ther
April 1995
273
:
26
-
31
Abstract
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Q Y Liu
,
B Li
,
J M Gang
,
E Karpinski
,
and
P K Pang
Tetrandrine, a Ca++ antagonist: effects and mechanisms of action in vascular smooth muscle cells.
J Pharmacol Exp Ther
April 1995
273
:
32
-
39
Abstract
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J Bergman
,
S Rosenzweig-Lipson
,
and
R D Spealman
Differential effects of dopamine D1 and D2 receptor agonists on schedule-controlled behavior of squirrel monkeys.
J Pharmacol Exp Ther
April 1995
273
:
40
-
48
Abstract
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K C Dines
,
N E Cameron
,
and
M A Cotter
Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats.
J Pharmacol Exp Ther
April 1995
273
:
49
-
55
Abstract
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A M Elhawary
and
C C Pang
Renal vascular and tubular actions of calcitonin gene-related peptide: effect of NG-nitro-L-arginine methyl ester.
J Pharmacol Exp Ther
April 1995
273
:
56
-
63
Abstract
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T A Christopher
,
B L Lopez
,
T L Yue
,
G Z Feuerstein
,
R R Ruffolo, Jr
,
and
X L Ma
Carvedilol, a new beta-adrenoreceptor blocker, vasodilator and free-radical scavenger, exerts an anti-shock and endothelial protective effect in rat splanchnic ischemia and reperfusion.
J Pharmacol Exp Ther
April 1995
273
:
64
-
71
Abstract
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M R Escobar
and
D S Sitar
Site-selective effect of bicarbonate on amantadine renal transport: quinine-sensitive in proximal vs quinidine-sensitive sites in distal tubules.
J Pharmacol Exp Ther
April 1995
273
:
72
-
79
Abstract
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J Mattana
and
P C Singhal
Heparin attenuates the effect of mitogenic vasoconstrictors on mesangial cell proliferation and handling of immunoglobulin G complexes.
J Pharmacol Exp Ther
April 1995
273
:
80
-
87
Abstract
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A C Rudy
,
P M Knight
,
D C Brater
,
and
S D Hall
Enantioselective disposition of ibuprofen in elderly persons with and without renal impairment.
J Pharmacol Exp Ther
April 1995
273
:
88
-
93
Abstract
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A I Haj-Yehia
and
L Z Benet
Dissociation of tissue thiols content from nitroglycerin-induced cyclic-3',5'-guanosine monophosphate and the state of tolerance: in vivo experiments in rats.
J Pharmacol Exp Ther
April 1995
273
:
94
-
100
Abstract
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R Schreiber
,
M Brocco
,
V Audinot
,
A Gobert
,
S Veiga
,
and
M J Millan
(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists.
J Pharmacol Exp Ther
April 1995
273
:
101
-
112
Abstract
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A Martelli
,
A Allavena
,
G B Campart
,
R Canonero
,
M Ghia
,
F Mattioli
,
E Mereto
,
L Robbiano
,
and
G Brambilla
In vitro and in vivo testing of hydralazine genotoxicity.
J Pharmacol Exp Ther
April 1995
273
:
113
-
120
Abstract
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L X Zhou
,
D K Finley
,
A E Hassell
,
and
J L Holtzman
Pharmacokinetic interaction between isradipine and lovastatin in normal, female and male volunteers.
J Pharmacol Exp Ther
April 1995
273
:
121
-
127
Abstract
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B Szabo
,
A Obergfell
,
and
K Starke
Involvement of monoamine uptake inhibition and local anesthesia in the cardiovascular response to cocaine in conscious rabbits.
J Pharmacol Exp Ther
April 1995
273
:
128
-
137
Abstract
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R Pellón
,
P Flores
,
K Alling
,
J M Witkin
,
and
J L Katz
Pharmacological analysis of the scratching produced by dopamine D2 agonists in squirrel monkeys.
J Pharmacol Exp Ther
April 1995
273
:
138
-
145
Abstract
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M J Makhuli
,
C A Polkowski
,
and
S M Grassl
Organic anion transport in rabbit renal basolateral membrane vesicles.
J Pharmacol Exp Ther
April 1995
273
:
146
-
153
Abstract
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R J MacAllister
,
A L Calver
,
J Riezebos
,
J Collier
,
and
P Vallance
Relative potency and arteriovenous selectivity of nitrovasodilators on human blood vessels: an insight into the targeting of nitric oxide delivery.
J Pharmacol Exp Ther
April 1995
273
:
154
-
160
Abstract
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I Gozes
,
G Lilling
,
R Glazer
,
A Ticher
,
I E Ashkenazi
,
A Davidson
,
S Rubinraut
,
M Fridkin
,
and
D E Brenneman
Superactive lipophilic peptides discriminate multiple vasoactive intestinal peptide receptors.
J Pharmacol Exp Ther
April 1995
273
:
161
-
167
Abstract
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A A Wallace
,
R F Stupienski, 3rd
,
E P Baskin
,
S D Appleby
,
T Kothstein
,
J R Gehret
,
S W King
,
D C Remy
,
and
J J Lynch, Jr
Cardiac electrophysiologic and antiarrhythmic actions of tedisamil.
J Pharmacol Exp Ther
April 1995
273
:
168
-
175
Abstract
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H J Showell
,
E R Pettipher
,
J B Cheng
,
R Breslow
,
M J Conklyn
,
C A Farrell
,
G P Hingorani
,
E D Salter
,
B C Hackman
,
and
D J Wimberly
The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696.
J Pharmacol Exp Ther
April 1995
273
:
176
-
184
Abstract
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C Yurdaydin
,
Y Li
,
J H Ha
,
E A Jones
,
R Rothman
,
and
A S Basile
Brain and plasma levels of opioid peptides are altered in rats with thioacetamide-induced fulminant hepatic failure: implications for the treatment of hepatic encephalopathy with opioid antagonists.
J Pharmacol Exp Ther
April 1995
273
:
185
-
192
Abstract
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E C O'Leary
,
J A Schelm
,
and
P J Simpson
Activated recombinant human protein C does not attenuate recruitment of neutrophils in rat models of acute inflammation.
J Pharmacol Exp Ther
April 1995
273
:
193
-
198
Abstract
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D R Kapusta
and
J C Obih
Central kappa opioids blunt the renal excretory responses to volume expansion by a renal nerve-dependent mechanism.
J Pharmacol Exp Ther
April 1995
273
:
199
-
205
Abstract
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W S Koo
,
P E Gengaro
,
T J Burke
,
and
R W Schrier
Verapamil attenuates calcium-induced mitochondrial swelling and respiratory dysfunction.
J Pharmacol Exp Ther
April 1995
273
:
206
-
212
Abstract
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M L Silverthorn
,
C M Dersch
,
M H Baumann
,
J L Cadet
,
J S Partilla
,
K C Rice
,
F I Carroll
,
K M Becketts
,
A Brockington
,
and
R B Rothman
Studies of the biogenic amine transporters. V. Demonstration of two binding sites for the cocaine analog [125I]RTI-55 associated with the 5-HT transporter in rat brain membranes.
J Pharmacol Exp Ther
April 1995
273
:
213
-
222
Abstract
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T Hirano
,
K Oka
,
and
T Tamaki
Gramicidin as a potential immunosuppressant for organ transplantation: suppression of human lymphocyte blastogenesis in vitro and prolongation of heart allograft survival in the rat.
J Pharmacol Exp Ther
April 1995
273
:
223
-
229
Abstract
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G Cuadra
and
E Giacobini
Coadministration of cholinesterase inhibitors and idazoxan: effects of neurotransmitters in rat cortex in vivo.
J Pharmacol Exp Ther
April 1995
273
:
230
-
240
Abstract
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L Dazzi
,
C Motzo
,
A Imperato
,
M Serra
,
G L Gessa
,
and
G Biggio
Modulation of basal and stress-induced release of acetylcholine and dopamine in rat brain by abecarnil and imidazenil, two anxioselective gamma-aminobutyric acidA receptor modulators.
J Pharmacol Exp Ther
April 1995
273
:
241
-
247
Abstract
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S S Bowersox
,
G P Miljanich
,
Y Sugiura
,
C Li
,
L Nadasdi
,
B B Hoffman
,
J Ramachandran
,
and
C P Ko
Differential blockade of voltage-sensitive calcium channels at the mouse neuromuscular junction by novel omega-conopeptides and omega-agatoxin-IVA.
J Pharmacol Exp Ther
April 1995
273
:
248
-
256
Abstract
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S S Greenberg
,
J Xie
,
J M Zatarain
,
D R Kapusta
,
and
M J Miller
Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents: role of nitric oxide.
J Pharmacol Exp Ther
April 1995
273
:
257
-
265
Abstract
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C Brugnara
,
C C Armsby
,
M Sakamoto
,
N Rifai
,
S L Alper
,
and
O Platt
Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: the imidazole ring is not required for inhibitory activity.
J Pharmacol Exp Ther
April 1995
273
:
266
-
272
Abstract
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W Billard
,
H Binch, 3rd
,
G Crosby
,
and
R D McQuade
Identification of the primary muscarinic autoreceptor subtype in rat striatum as m2 through a correlation of in vivo microdialysis and in vitro receptor binding data.
J Pharmacol Exp Ther
April 1995
273
:
273
-
279
Abstract
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W C Elliott
and
D S Patchin
Effects and interactions of gentamicin, polyaspartic acid and diuretics on urine calcium concentration.
J Pharmacol Exp Ther
April 1995
273
:
280
-
284
Abstract
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D F Woodward
,
C E Fairbairn
,
A H Krauss
,
R A Lawrence
,
and
C E Protzman
Radioligand binding analysis of receptor subtypes in two FP receptor preparations that exhibit different functional rank orders of potency in response to prostaglandins.
J Pharmacol Exp Ther
April 1995
273
:
285
-
287
Abstract
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L P Hooke
,
L He
,
and
N M Lee
Dynorphin A modulates acute and chronic opioid effects.
J Pharmacol Exp Ther
April 1995
273
:
292
-
297
Abstract
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E G Chikhale
,
P S Burton
,
and
R T Borchardt
The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: kinetic evidence for an apically polarized efflux mechanism.
J Pharmacol Exp Ther
April 1995
273
:
298
-
303
Abstract
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A S Eison
,
R P Freeman
,
V B Guss
,
U L Mullins
,
and
R N Wright
Melatonin agonists modulate 5-HT2A receptor-mediated neurotransmission: behavioral and biochemical studies in the rat.
J Pharmacol Exp Ther
April 1995
273
:
304
-
308
Abstract
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T Akai
,
M Ozawa
,
M Yamaguchi
,
E Mizuta
,
and
S Kuno
Combination treatment of the partial D2 agonist terguride with the D1 agonist SKF 82958 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned parkinsonian cynomolgus monkeys.
J Pharmacol Exp Ther
April 1995
273
:
309
-
314
Abstract
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S D Nelson
,
K S Coyne
,
and
J Meimer
The discordant influences of infarct healing on the electrophysiologic effects of procainamide and N-acetylprocainamide.
J Pharmacol Exp Ther
April 1995
273
:
315
-
319
Abstract
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C E Crosson
Adenosine receptor activation modulates intraocular pressure in rabbits.
J Pharmacol Exp Ther
April 1995
273
:
320
-
326
Abstract
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M A Klitenick
and
D Wirtshafter
Behavioral and neurochemical effects of opioids in the paramedian midbrain tegmentum including the median raphe nucleus and ventral tegmental area.
J Pharmacol Exp Ther
April 1995
273
:
327
-
336
Abstract
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R Mathison
and
J S Davison
Regulation of jejunal arterioles by capsaicin-sensitive nerves in Nippostrongylus brasiliensis-sensitized rats.
J Pharmacol Exp Ther
April 1995
273
:
337
-
343
Abstract
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W L Hasler
,
S Kurosawa
,
T Takahashi
,
H Feng
,
T S Gaginella
,
and
C Owyang
Bradykinin acting on B2 receptors contracts colon circular muscle cells by IP3 generation and adenylate cyclase inhibition.
J Pharmacol Exp Ther
April 1995
273
:
344
-
350
Abstract
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C R Rush
,
J T Sullivan
,
and
R R Griffiths
Intravenous caffeine in stimulant drug abusers: subjective reports and physiological effects.
J Pharmacol Exp Ther
April 1995
273
:
351
-
358
Abstract
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E J Bilsky
,
S N Calderon
,
T Wang
,
R N Bernstein
,
P Davis
,
V J Hruby
,
R W McNutt
,
R B Rothman
,
K C Rice
,
and
F Porreca
SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist.
J Pharmacol Exp Ther
April 1995
273
:
359
-
366
Abstract
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H Miwa
,
I Gantz
,
Y Konda
,
Y Shimoto
,
and
T Yamada
Structural determinants of the melanocortin peptides required for activation of melanocortin-3 and melanocortin-4 receptors.
J Pharmacol Exp Ther
April 1995
273
:
367
-
372
Abstract
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S R George
,
T Fan
,
G Y Ng
,
S Y Jung
,
B F O'Dowd
,
and
C A Naranjo
Low endogenous dopamine function in brain predisposes to high alcohol preference and consumption: reversal by increasing synaptic dopamine.
J Pharmacol Exp Ther
April 1995
273
:
373
-
379
Abstract
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S F Morrison
and
Y Z Ge
Adrenergic modulation of a spinal sympathetic reflex in the rat.
J Pharmacol Exp Ther
April 1995
273
:
380
-
385
Abstract
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T J Cicero
,
B Nock
,
L O'Connor
,
M Adams
,
and
E R Meyer
Adverse effects of paternal opiate exposure on offspring development and sensitivity to morphine-induced analgesia.
J Pharmacol Exp Ther
April 1995
273
:
386
-
392
Abstract
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J E Ruscoe
,
H Jewell
,
J L Maggs
,
P M O'Neill
,
R C Storr
,
S A Ward
,
and
B K Park
The effect of chemical substitution on the metabolic activation, metabolic detoxication, and pharmacological activity of amodiaquine in the mouse.
J Pharmacol Exp Ther
April 1995
273
:
393
-
404
Abstract
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R A Mathôt
,
B C Van den Aarsen
,
W Soudijn
,
D D Breimer
,
A P Ijzerman
,
and
M Danhof
Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of R- and S-N6-phenylisopropyladenosine in conscious normotensive rats.
J Pharmacol Exp Ther
April 1995
273
:
405
-
414
Abstract
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J P Wagner
,
F J Seidler
,
S E Lappi
,
E C McCook
,
and
T A Slotkin
Role of presynaptic input in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase and c-fos protooncogene expression.
J Pharmacol Exp Ther
April 1995
273
:
415
-
426
Abstract
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R Martini
,
A M Butler
,
X M Jiang
,
and
M Murray
Pretranslational down regulation of cytochrome P450 2C11 in vitamin A-deficient male rat liver: prevention by dietary inclusion of retinoic acid.
J Pharmacol Exp Ther
April 1995
273
:
427
-
434
Abstract
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V J Aloyo
,
J S Ruffin
,
P S Pazdalski
,
A L Kirifides
,
and
J A Harvey
[3H]WIN 35,428 binding in the caudate nucleus of the rabbit: evidence for a single site on the dopamine transporter.
J Pharmacol Exp Ther
April 1995
273
:
435
-
444
Abstract
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F J White
,
X T Hu
,
X F Zhang
,
and
M E Wolf
Repeated administration of cocaine or amphetamine alters neuronal responses to glutamate in the mesoaccumbens dopamine system.
J Pharmacol Exp Ther
April 1995
273
:
445
-
454
Abstract
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S M Sadrzadeh
,
M Meydani
,
U Khettry
,
and
A A Nanji
High-dose vitamin E supplementation has no effect on ethanol-induced pathological liver injury.
J Pharmacol Exp Ther
April 1995
273
:
455
-
460
Abstract
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D A Walsh
,
P I Mapp
,
J M Polak
,
and
D R Blake
Autoradiographic localization and characterization of [3H]alpha-trinositol (1D-myo-inositol 1,2,6-trisphosphate) binding sites in human and mammalian tissues.
J Pharmacol Exp Ther
April 1995
273
:
461
-
469
Abstract
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S I Zakharov
,
R A Wagner
,
and
R D Harvey
Muscarinic regulation of the cardiac CFTR Cl- current by quaternary ammonium compounds.
J Pharmacol Exp Ther
April 1995
273
:
470
-
481
Abstract
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U D Sohn
,
B Han
,
A H Tashjian, Jr
,
J Behar
,
and
P Biancani
Agonist-independent, muscle-type-specific signal transduction pathways in cat esophageal and lower esophageal sphincter circular smooth muscle.
J Pharmacol Exp Ther
April 1995
273
:
482
-
491
Abstract
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H Y Wang
,
S Runyan
,
E Yadin
,
and
E Friedman
Prenatal exposure to cocaine selectively reduces D1 dopamine receptor-mediated activation of striatal Gs proteins.
J Pharmacol Exp Ther
April 1995
273
:
492
-
498
Abstract
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Z K Krowicki
and
P J Hornby
Serotonin and thyrotropin-releasing hormone do not augment their effects on gastric motility on their microinjection into the nucleus raphe obscurus of the rat.
J Pharmacol Exp Ther
April 1995
273
:
499
-
508
Abstract
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S Kim
,
K Ohta
,
A Hamaguchi
,
T Omura
,
T Yukimura
,
K Miura
,
Y Inada
,
Y Ishimura
,
F Chatani
,
and
H Iwao
Angiotensin II type I receptor antagonist inhibits the gene expression of transforming growth factor-beta 1 and extracellular matrix in cardiac and vascular tissues of hypertensive rats.
J Pharmacol Exp Ther
April 1995
273
:
509
-
515
Abstract
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B A Heidenreich
,
R B Mailman
,
D E Nichols
,
and
T C Napier
Partial and full dopamine D1 agonists produce comparable increases in ventral pallidal neuronal activity: contribution of endogenous dopamine.
J Pharmacol Exp Ther
April 1995
273
:
516
-
525
Abstract
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H E Criswell
,
P E Simson
,
D J Knapp
,
L L Devaud
,
T J McCown
,
G E Duncan
,
A L Morrow
,
and
G R Breese
Effect of zolpidem on gamma-aminobutyric acid (GABA)-induced inhibition predicts the interaction of ethanol with GABA on individual neurons in several rat brain regions.
J Pharmacol Exp Ther
April 1995
273
:
526
-
536
Abstract
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W J Pan
,
S S Osmanović
,
and
S A Shefner
Characterization of the adenosine A1 receptor-activated potassium current in rat locus ceruleus neurons.
J Pharmacol Exp Ther
April 1995
273
:
537
-
544
Abstract
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M T Runnegar
,
T Maddatu
,
L D Deleve
,
N Berndt
,
and
S Govindarajan
Differential toxicity of the protein phosphatase inhibitors microcystin and calyculin A.
J Pharmacol Exp Ther
April 1995
273
:
545
-
553
Abstract
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J J Lynch, 3rd
,
S P Yu
,
L M Canzoniero
,
S L Sensi
,
and
D W Choi
Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists.
J Pharmacol Exp Ther
April 1995
273
:
554
-
560
Abstract
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R P Lee
and
P G Forkert
Pulmonary CYP2E1 bioactivates 1,1-dichloroethylene in male and female mice.
J Pharmacol Exp Ther
April 1995
273
:
561
-
567
Abstract
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