Table of Contents

Select this article
- J A Keiser,
- M J Ryan,
- R L Panek,
- J C Hodges,
- and I Sircar
Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist.
J Pharmacol Exp Ther March 1995 272:963-969
- Abstract
- Full Text (PDF)
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- D B Joseph and
- J M Bidlack
The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure.
J Pharmacol Exp Ther March 1995 272:970-976
- Abstract
- Full Text (PDF)
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- P Rondé,
- H Ansanay,
- A Dumuis,
- R Miller,
- and J Bockaert
Homologous desensitization of 5-hydroxytryptamine4 receptors in rat esophagus: functional and second messenger studies.
J Pharmacol Exp Ther March 1995 272:977-983
- Abstract
- Full Text (PDF)
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- M Pirmohamed,
- D Williams,
- S Madden,
- E Templeton,
- and B K Park
Metabolism and bioactivation of clozapine by human liver in vitro.
J Pharmacol Exp Ther March 1995 272:984-990
- Abstract
- Full Text (PDF)
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- H A el-Fawal and
- R W Wood
Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine.
J Pharmacol Exp Ther March 1995 272:991-996
- Abstract
- Full Text (PDF)
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- J L Ellis and
- N D Conanan
Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea.
J Pharmacol Exp Ther March 1995 272:997-1004
- Abstract
- Full Text (PDF)
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- R S Sheldon and
- E Thakore
Ring and link requirements for tocainide binding to the class I antiarrhythmic drug receptor on rat cardiac myocytes.
J Pharmacol Exp Ther March 1995 272:1005-1010
- Abstract
- Full Text (PDF)
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- W R Tracey,
- J Tse,
- and G Carter
Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.
J Pharmacol Exp Ther March 1995 272:1011-1015
- Abstract
- Full Text (PDF)
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- M F Hare and
- W D Atchison
Methylmercury mobilizes Ca++ from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells.
J Pharmacol Exp Ther March 1995 272:1016-1023
- Abstract
- Full Text (PDF)
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- D M Dennis,
- J C Shryock,
- and L Belardinelli
Homologous desensitization of the A1-adenosine receptor system in the guinea pig atrioventricular node.
J Pharmacol Exp Ther March 1995 272:1024-1035
- Abstract
- Full Text (PDF)
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- C Scavone,
- C Scanlon,
- M McKee,
- and J A Nathanson
Atrial natriuretic peptide modulates sodium and potassium-activated adenosine triphosphatase through a mechanism involving cyclic GMP and cyclic GMP-dependent protein kinase.
J Pharmacol Exp Ther March 1995 272:1036-1043
- Abstract
- Full Text (PDF)
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- M Matsumoto,
- M Yoshioka,
- H Togashi,
- M Tochihara,
- T Ikeda,
- and H Saito
Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis.
J Pharmacol Exp Ther March 1995 272:1044-1051
- Abstract
- Full Text (PDF)
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- D E Semler,
- E H Ohlstein,
- P Nambi,
- C Slater,
- and P H Stern
Endothelin-1-evoked calcium transients in UMR-106 osteoblastic osteosarcoma cells are mediated through endothelin-A and endothelin-B receptors.
J Pharmacol Exp Ther March 1995 272:1052-1058
- Abstract
- Full Text (PDF)
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- N K Mello,
- Z Sarnyai,
- J H Mendelson,
- J M Drieze,
- and M Kelly
The acute effects of cocaine on anterior pituitary hormones in ovariectomized rhesus monkeys.
J Pharmacol Exp Ther March 1995 272:1059-1066
- Abstract
- Full Text (PDF)
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- A Katoh,
- M Eigyo,
- C Ishibashi,
- Y Naitoh,
- M Takeuchi,
- N Ibii,
- M Ikeda,
- and A Matsushita
Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats.
J Pharmacol Exp Ther March 1995 272:1067-1075
- Abstract
- Full Text (PDF)
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- J O Miners,
- D L Rees,
- L Valente,
- M E Veronese,
- and D J Birkett
Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism.
J Pharmacol Exp Ther March 1995 272:1076-1081
- Abstract
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- R Patacchini,
- L Quartara,
- M Astolfi,
- C Goso,
- A Giachetti,
- and C A Maggi
Activity of cyclic pseudopeptide antagonists at peripheral tachykinin receptors.
J Pharmacol Exp Ther March 1995 272:1082-1087
- Abstract
- Full Text (PDF)
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- H Zhong and
- K P Minneman
Coexisting beta-1 and beta-2-adrenergic receptors with differential receptor reserves in rat C6 glioma cells.
J Pharmacol Exp Ther March 1995 272:1088-1094
- Abstract
- Full Text (PDF)
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- S Takahashi,
- Y Kato,
- M Adachi,
- N Agata,
- H Tanaka,
- and K Shigenobu
Effects of cyclopiazonic acid on rat myocardium: inhibition of calcium uptake into sarcoplasmic reticulum.
J Pharmacol Exp Ther March 1995 272:1095-1100
- Abstract
- Full Text (PDF)
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- K Igarashi and
- K Williams
Antagonist properties of polyamines and bis(ethyl)polyamines at N-methyl-D-aspartate receptors.
J Pharmacol Exp Ther March 1995 272:1101-1109
- Abstract
- Full Text (PDF)
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- A Parent,
- W Rowe,
- M J Meaney,
- and R Quirion
Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors.
J Pharmacol Exp Ther March 1995 272:1110-1116
- Abstract
- Full Text (PDF)
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- D E Keyler,
- D G Le Couteur,
- S M Pond,
- J V St Peter,
- and P R Pentel
Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated, perfused liver.
J Pharmacol Exp Ther March 1995 272:1117-1123
- Abstract
- Full Text (PDF)
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- M L Webb,
- J E Bird,
- E C Liu,
- P M Rose,
- R Serafino,
- P D Stein,
- and S Moreland
BMS-182874 is a selective, nonpeptide endothelin ETA receptor antagonist.
J Pharmacol Exp Ther March 1995 272:1124-1134
- Abstract
- Full Text (PDF)
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- T J Martin,
- S I Dworkin,
- and J E Smith
Alkylation of mu opioid receptors by beta-funaltrexamine in vivo: comparison of the effects on in situ binding and heroin self-administration in rats.
J Pharmacol Exp Ther March 1995 272:1135-1140
- Abstract
- Full Text (PDF)
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- J S Fedan,
- T E Warner,
- L X Yuan,
- V a Robinson,
- and D G Frazer
Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.
J Pharmacol Exp Ther March 1995 272:1141-1150
- Abstract
- Full Text (PDF)
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- S Takayanagi,
- H Hanai,
- J Kumagai,
- and E Kaneko
Serotonin uptake and its modulation in rat jejunal enterocyte preparation.
J Pharmacol Exp Ther March 1995 272:1151-1159
- Abstract
- Full Text (PDF)
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- A A Hancock,
- S A Buckner,
- W J Giardina,
- M E Brune,
- J Y Lee,
- P A Morse,
- K W Oheim,
- D S Stanisic,
- R B Warner,
- and D J Kerkman
Preclinical pharmacological actions of (+/-)-(1'R*,3R*)-3-phenyl-1- [1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200), a potential antidepressant agent that antagonizes alpha-2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine.
J Pharmacol Exp Ther March 1995 272:1160-1169
- Abstract
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- S Nishino,
- J Shelton,
- A Renaud,
- W C Dement,
- and E Mignot
Effect of 5-HT1A receptor agonists and antagonists on canine cataplexy.
J Pharmacol Exp Ther March 1995 272:1170-1175
- Abstract
- Full Text (PDF)
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- B A Bennett,
- C H Wichems,
- C K Hollingsworth,
- H M Davies,
- C Thornley,
- T Sexton,
- and S R Childers
Novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain.
J Pharmacol Exp Ther March 1995 272:1176-1186
- Abstract
- Full Text (PDF)
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- J W Van Huysse,
- D P Henry,
- and L R Willis
In vivo renal production and tubular secretion of tyramine.
J Pharmacol Exp Ther March 1995 272:1187-1192
- Abstract
- Full Text (PDF)
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- K Shinozuka,
- M Kunitomo,
- K Hattori,
- R A Bjur,
- and D P Westfall
Differences in purinoceptor modulation of norepinephrine release between caudal arteries of normotensive and hypertensive rats.
J Pharmacol Exp Ther March 1995 272:1193-1198
- Abstract
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- D W Bonhaus,
- K R Bley,
- C A Broka,
- D J Fontana,
- E Leung,
- R Lewis,
- A Shieh,
- and E H Wong
Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine.
J Pharmacol Exp Ther March 1995 272:1199-1203
- Abstract
- Full Text (PDF)
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- P L Smith,
- C P Lee,
- M Pullen,
- E H Ohlstein,
- G Beck,
- E P Eddy,
- and P Nambi
Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects.
J Pharmacol Exp Ther March 1995 272:1204-1210
- Abstract
- Full Text (PDF)
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- S Rattan,
- G J Rosenthal,
- and S Chakder
Human recombinant hemoglobin (rHb1.1) inhibits nonadrenergic noncholinergic (NANC) nerve-mediated relaxation of internal anal sphincter.
J Pharmacol Exp Ther March 1995 272:1211-1216
- Abstract
- Full Text (PDF)
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- K Van Belle,
- S Sarre,
- G Ebinger,
- and Y Michotte
Brain, liver and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: a quantitative microdialysis study.
J Pharmacol Exp Ther March 1995 272:1217-1222
- Abstract
- Full Text (PDF)
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- M Kähönen,
- H Mäkynen,
- P Arvola,
- H Wuorela,
- and I Pörsti
Arterial function after trichlormethiazide therapy in spontaneously hypertensive rats.
J Pharmacol Exp Ther March 1995 272:1223-1230
- Abstract
- Full Text (PDF)
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- S A Azer,
- V Kukongviriyapan,
- and N H Stacey
Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes.
J Pharmacol Exp Ther March 1995 272:1231-1237
- Abstract
- Full Text (PDF)
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- G Bannenberg,
- J Xue,
- L Engman,
- I Cotgreave,
- P Moldéus,
- and A Ryrfeldt
Characterization of bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung.
J Pharmacol Exp Ther March 1995 272:1238-1245
- Abstract
- Full Text (PDF)
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- L R Flores,
- S M Wahl,
- and B M Bayer
Mechanisms of morphine-induced immunosuppression: effect of acute morphine administration on lymphocyte trafficking.
J Pharmacol Exp Ther March 1995 272:1246-1251
- Abstract
- Full Text (PDF)
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- M Sato,
- J Kim,
- L L Short,
- C W Slemenda,
- and H U Bryant
Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats.
J Pharmacol Exp Ther March 1995 272:1252-1259
- Abstract
- Full Text (PDF)
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- I Mitrovic and
- T C Napier
Electrophysiological demonstration of mu, delta and kappa opioid receptors in the ventral pallidum.
J Pharmacol Exp Ther March 1995 272:1260-1270
- Abstract
- Full Text (PDF)
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- O Pol,
- E Planas,
- and M M Puig
Peripheral effects of naloxone in mice with acute diarrhea associated with intestinal inflammation.
J Pharmacol Exp Ther March 1995 272:1271-1276
- Abstract
- Full Text (PDF)
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- E M Mokrzan,
- L E Kerper,
- N Ballatori,
- and T W Clarkson
Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L.
J Pharmacol Exp Ther March 1995 272:1277-1284
- Abstract
- Full Text (PDF)
Select this article
- I Khan,
- N Lapierre,
- and P K Rangachari
Messenger RNAs for neurokinin and histamine receptor subtypes in isolated canine colonic crypts.
J Pharmacol Exp Ther March 1995 272:1285-1292
- Abstract
- Full Text (PDF)
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- S E Shehin-Johnson,
- D E Williams,
- S Larsen-Su,
- D M Stresser,
- and R N Hines
Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit.
J Pharmacol Exp Ther March 1995 272:1293-1299
- Abstract
- Full Text (PDF)
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- K Kaechi,
- R Ikegami,
- N Nakamura,
- M Nakajima,
- Y Furukawa,
- and S Furukawa
4-Methylcatechol, an inducer of nerve growth factor synthesis, enhances peripheral nerve regeneration across nerve gaps.
J Pharmacol Exp Ther March 1995 272:1300-1304
- Abstract
- Full Text (PDF)
Select this article
- X Tao,
- J J Cai,
- and P E Lipsky
The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook. F.
J Pharmacol Exp Ther March 1995 272:1305-1312
- Abstract
- Full Text (PDF)
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- M W Verghese,
- R T McConnell,
- A B Strickland,
- R C Gooding,
- S A Stimpson,
- D P Yarnall,
- J D Taylor,
- and P J Furdon
Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors.
J Pharmacol Exp Ther March 1995 272:1313-1320
- Abstract
- Full Text (PDF)

Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist.

The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure.

Homologous desensitization of 5-hydroxytryptamine4 receptors in rat esophagus: functional and second messenger studies.

Metabolism and bioactivation of clozapine by human liver in vitro.

Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine.

Modulation of relaxant responses evoked by a nitric oxide donor and by nonadrenergic, noncholinergic stimulation by isozyme-selective phosphodiesterase inhibitors in guinea pig trachea.

Ring and link requirements for tocainide binding to the class I antiarrhythmic drug receptor on rat cardiac myocytes.

Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.

Methylmercury mobilizes Ca++ from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells.

Homologous desensitization of the A1-adenosine receptor system in the guinea pig atrioventricular node.

Atrial natriuretic peptide modulates sodium and potassium-activated adenosine triphosphatase through a mechanism involving cyclic GMP and cyclic GMP-dependent protein kinase.

Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis.

Endothelin-1-evoked calcium transients in UMR-106 osteoblastic osteosarcoma cells are mediated through endothelin-A and endothelin-B receptors.

The acute effects of cocaine on anterior pituitary hormones in ovariectomized rhesus monkeys.

Behavioral and electroencephalographic properties of duloxetine (LY248686), a reuptake inhibitor of norepinephrine and serotonin, in mice and rats.

Human hepatic cytochrome P450 2C9 catalyzes the rate-limiting pathway of torsemide metabolism.

Activity of cyclic pseudopeptide antagonists at peripheral tachykinin receptors.

Coexisting beta-1 and beta-2-adrenergic receptors with differential receptor reserves in rat C6 glioma cells.

Effects of cyclopiazonic acid on rat myocardium: inhibition of calcium uptake into sarcoplasmic reticulum.

Antagonist properties of polyamines and bis(ethyl)polyamines at N-methyl-D-aspartate receptors.

Increased production of inositol phosphates and diacylglycerol in aged cognitively impaired rats after stimulation of muscarinic, metabotropic-glutamate and endothelin receptors.

Effects of specific antibody Fab fragments on desipramine pharmacokinetics in the rat in vivo and in the isolated, perfused liver.

BMS-182874 is a selective, nonpeptide endothelin ETA receptor antagonist.

Alkylation of mu opioid receptors by beta-funaltrexamine in vivo: comparison of the effects on in situ binding and heroin self-administration in rats.

Nitric oxide synthase inhibitor and lipopolysaccharide effects on reactivity of guinea pig airways.

Serotonin uptake and its modulation in rat jejunal enterocyte preparation.

Effect of 5-HT1A receptor agonists and antagonists on canine cataplexy.

Novel 2-substituted cocaine analogs: uptake and ligand binding studies at dopamine, serotonin and norepinephrine transport sites in the rat brain.

In vivo renal production and tubular secretion of tyramine.

Differences in purinoceptor modulation of norepinephrine release between caudal arteries of normotensive and hypertensive rats.

Characterization of the electrophysiological, biochemical and behavioral actions of epibatidine.

Nonpeptide endothelin receptor antagonists: IV. Identification of receptors in rabbit colonic mucosa and smooth muscle and correlation with physiological effects.

Human recombinant hemoglobin (rHb1.1) inhibits nonadrenergic noncholinergic (NANC) nerve-mediated relaxation of internal anal sphincter.

Brain, liver and blood distribution kinetics of carbamazepine and its metabolic interaction with clomipramine in rats: a quantitative microdialysis study.

Arterial function after trichlormethiazide therapy in spontaneously hypertensive rats.

Mechanism of ketoconazole-induced elevation of individual serum bile acids in the rat: relationship to the effect of ketoconazole on bile acid uptake by isolated hepatocytes.

Characterization of bronchodilator effects and fate of S-nitrosothiols in the isolated perfused and ventilated guinea pig lung.

Mechanisms of morphine-induced immunosuppression: effect of acute morphine administration on lymphocyte trafficking.

Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats.

Electrophysiological demonstration of mu, delta and kappa opioid receptors in the ventral pallidum.

Peripheral effects of naloxone in mice with acute diarrhea associated with intestinal inflammation.

Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L.

Messenger RNAs for neurokinin and histamine receptor subtypes in isolated canine colonic crypts.

Tissue-specific expression of flavin-containing monooxygenase (FMO) forms 1 and 2 in the rabbit.

4-Methylcatechol, an inducer of nerve growth factor synthesis, enhances peripheral nerve regeneration across nerve gaps.

The identity of immunosuppressive components of the ethyl acetate extract and chloroform methanol extract (T2) of Tripterygium wilfordii Hook. F.

Differential regulation of human monocyte-derived TNF alpha and IL-1 beta by type IV cAMP-phosphodiesterase (cAMP-PDE) inhibitors.

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