Table of Contents

December 1994; 271 (3)

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- F Noble,
- C Smadja,
- and B P Roques
Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.
J Pharmacol Exp Ther December 1994 271:1127-1134
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- Z Li,
- V Barrios,
- J N Buchholz,
- T C Glenn,
- and S P Duckles
Chronic nicotine administration does not affect peripheral vascular reactivity in the rat.
J Pharmacol Exp Ther December 1994 271:1135-1142
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- P J Silver,
- R L Dundore,
- D C Bode,
- L de Garavilla,
- R A Buchholz,
- G van Aller,
- L T Hamel,
- E Bacon,
- B Singh,
- and G Y Lesher
Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor.
J Pharmacol Exp Ther December 1994 271:1143-1149
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- A A Abdel-Rahman
Acute effects of ethanol on cardiac output and its derivatives in spontaneously hypertensive and normotensive rats.
J Pharmacol Exp Ther December 1994 271:1150-1158
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- D W Wilde
Isoflurane reduces Ca++ channel current and accelerates current decay in guinea pig portal vein smooth muscle cells.
J Pharmacol Exp Ther December 1994 271:1159-1166
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- G Dent,
- M A Giembycz,
- P M Evans,
- K F Rabe,
- and P J Barnes
Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoceptor agonist albuterol.
J Pharmacol Exp Ther December 1994 271:1167-1174
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- A M Lin,
- R K Freund,
- B J Hoffer,
- and M R Palmer
Ethanol-induced depressions of cerebellar Purkinje neurons are potentiated by beta-adrenergic mechanisms in rat brain.
J Pharmacol Exp Ther December 1994 271:1175-1180
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- M L Pucak and
- A A Grace
Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors.
J Pharmacol Exp Ther December 1994 271:1181-1192
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- U Schröder,
- H Schröder,
- W Augustin,
- and B A Sabel
Haloperidol-induced behavioral supersensitivity is increased by monosialoganglioside treatment in rats without affecting spiroperidol-binding.
J Pharmacol Exp Ther December 1994 271:1193-1196
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- J H Lin,
- I W Chen,
- and T H Lin
Blood-brain barrier permeability and in vivo activity of partial agonists of benzodiazepine receptor: a study of L-663,581 and its metabolites in rats.
J Pharmacol Exp Ther December 1994 271:1197-1202
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- M S Chintala,
- V Bernardino,
- and P J Chiu
Cyclic GMP but not cyclic AMP prevents renal platelet accumulation after ischemia-reperfusion in anesthetized rats.
J Pharmacol Exp Ther December 1994 271:1203-1208
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- N Lepretre,
- S Arnaudeau,
- J Mironneau,
- L Rakotoarisoa,
- C Mironneau,
- and A Galiano
Electrophysiological and radioligand binding studies of elgodipine and derivatives in portal vein myocytes.
J Pharmacol Exp Ther December 1994 271:1209-1215
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- M H Baumann,
- G U Char,
- B R De Costa,
- K C Rice,
- and R B Rothman
GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat.
J Pharmacol Exp Ther December 1994 271:1216-1222
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- S S Shetty and
- D DelGrande
Inhibition by nickel of endothelin-1-induced tension and associated 45Ca movements in rabbit aorta.
J Pharmacol Exp Ther December 1994 271:1223-1227
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- A S Goetz,
- M W Lutz,
- T J Rimele,
- and D L Saussy, Jr
Characterization of alpha-1 adrenoceptor subtypes in human and canine prostate membranes.
J Pharmacol Exp Ther December 1994 271:1228-1233
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- S E Robinson,
- E K Enters,
- G F Jackson,
- V M Chinchilli,
- J R Maher,
- K P McDowell,
- H M Allen,
- and H Guo
Maternal and fetal brain and plasma levels of cocaine and benzoylecgonine after acute or chronic maternal intravenous administration of cocaine.
J Pharmacol Exp Ther December 1994 271:1234-1239
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- T H Chen and
- W H Hsu
Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP.
J Pharmacol Exp Ther December 1994 271:1240-1245
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- E Meller and
- K Bohmaker
Differential receptor reserve for 5-HT1A receptor-mediated regulation of plasma neuroendocrine hormones.
J Pharmacol Exp Ther December 1994 271:1246-1252
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- A Chaudhry and
- J G Granneman
Influence of cell type upon the desensitization of the beta 3-adrenergic receptor.
J Pharmacol Exp Ther December 1994 271:1253-1258
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- M Imamura,
- E Poli,
- A T Omoniyi,
- and R Levi
Unmasking of activated histamine H3-receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release.
J Pharmacol Exp Ther December 1994 271:1259-1266
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- S Yanai,
- H Okada,
- M Misaki,
- K Saito,
- Y Kuge,
- Y Ogawa,
- and H Toguchi
Antitumor activity of a medium-chain triglyceride solution of the angiogenesis inhibitor TNP-470 (AGM-1470) when administered via the hepatic artery to rats bearing Walker 256 carcinosarcoma in the liver.
J Pharmacol Exp Ther December 1994 271:1267-1273
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- D J Pillion,
- J A Atchison,
- R X Wang,
- and E Meezan
Alkylglycosides enhance systemic absorption of insulin applied topically to the rat eye.
J Pharmacol Exp Ther December 1994 271:1274-1280
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- J S Kreeger,
- K F Kitto,
- and A A Larson
Substance P N-terminal metabolites and nitric oxide mediate capsaicin-induced antinociception in the adult mouse.
J Pharmacol Exp Ther December 1994 271:1281-1285
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- M S Dordal,
- M Jackson-Stone,
- A C Ho,
- J N Winter,
- and A J Atkinson, Jr
Decreased intracellular compartmentalization of doxorubicin in cell lines expressing P-glycoprotein.
J Pharmacol Exp Ther December 1994 271:1286-1290
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- Y H Lee,
- K Spuhler-Phillips,
- P K Randall,
- and S W Leslie
Effects of prenatal ethanol exposure on N-methyl-D-aspartate-mediated calcium entry into dissociated neurons.
J Pharmacol Exp Ther December 1994 271:1291-1298
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- D Krajnc,
- T A Wemlinger,
- N H Neff,
- and M Hadjiconstantinou
Neonatal hypoxia: early neurotransmitter responses and the consequences of treatment with GM1 ganglioside.
J Pharmacol Exp Ther December 1994 271:1299-1305
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- J J Idänpään-Heikkilä,
- E A Kalso,
- and T Seppälä
Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50,488H against noxious thermal, mechanical and inflammatory stimuli.
J Pharmacol Exp Ther December 1994 271:1306-1313
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- A Wilkinson,
- M Courtney,
- A Westlind-Danielsson,
- G Hallnemo,
- and K E Akerman
Alaproclate acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow.
J Pharmacol Exp Ther December 1994 271:1314-1319
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- K T Delle Donne and
- P K Sonsalla
Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
J Pharmacol Exp Ther December 1994 271:1320-1326
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- M Ries,
- U Wenzel,
- and H Daniel
Transport of cefadroxil in rat kidney brush-border membranes is mediated by two electrogenic H+-coupled systems.
J Pharmacol Exp Ther December 1994 271:1327-1333
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- S Verma,
- S Bhanot,
- and J H McNeill
Antihypertensive effects of metformin in fructose-fed hyperinsulinemic, hypertensive rats.
J Pharmacol Exp Ther December 1994 271:1334-1337
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- A Björk,
- E Christensson,
- A Albinsson,
- B Gustafsson,
- E Pettersson,
- G Pettersson,
- J Svartengren,
- and G Andersson
In the search for a novel class of antipsychotic drugs: preclinical pharmacology of FG5803, a 1-piperazinecarboxamide derivative.
J Pharmacol Exp Ther December 1994 271:1338-1347
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- G Romey and
- M Lazdunski
Effects of a new class of calcium antagonists, SR33557 (fantofarone) and SR33805, on neuronal voltage-activated Ca++ channels.
J Pharmacol Exp Ther December 1994 271:1348-1352
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- C Cussac,
- M Rapp,
- E Mounetou,
- J C Madelmont,
- J C Maurizis,
- D Godeneche,
- J M Dupuy,
- J Sauzieres,
- J P Baudry,
- and A Veyre
Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.
J Pharmacol Exp Ther December 1994 271:1353-1358
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- K Amano,
- M Hori,
- H Ozaki,
- Y Matsuda,
- and H Karaki
Ca++ mobilization mediated by endothelin ETA receptor in endothelium of rabbit aortic valve.
J Pharmacol Exp Ther December 1994 271:1359-1364
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- Yukhananov RYu and
- A A Larson
Involvement of NMDA receptors in naloxone-induced contractions of the isolated guinea pig ileum after preincubation with morphine.
J Pharmacol Exp Ther December 1994 271:1365-1370
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- L Belardinelli,
- J Lu,
- D Dennis,
- J Martens,
- and J C Shryock
The cardiac effects of a novel A1-adenosine receptor agonist in guinea pig isolated heart.
J Pharmacol Exp Ther December 1994 271:1371-1382
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- F Fan,
- D R Compton,
- S Ward,
- L Melvin,
- and B R Martin
Development of cross-tolerance between delta 9-tetrahydrocannabinol, CP 55,940 and WIN 55,212.
J Pharmacol Exp Ther December 1994 271:1383-1390
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- G Schulteis,
- A Markou,
- L H Gold,
- L Stinus,
- and G F Koob
Relative sensitivity to naloxone of multiple indices of opiate withdrawal: a quantitative dose-response analysis.
J Pharmacol Exp Ther December 1994 271:1391-1398
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- D C Argentieri,
- D M Ritchie,
- M P Ferro,
- T Kirchner,
- M P Wachter,
- D W Anderson,
- M E Rosenthale,
- and R J Capetola
Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.
J Pharmacol Exp Ther December 1994 271:1399-1408
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- C P Cheng,
- K Pettersson,
- and W C Little
Effects of felodipine on left ventricular systolic and diastolic performance in congestive heart failure.
J Pharmacol Exp Ther December 1994 271:1409-1417
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- P R Farina,
- A G Graham,
- A F Hoffman,
- J M Watrous,
- P Borgeat,
- M Nadeau,
- G Hansen,
- R M Dinallo,
- J Adams,
- and C K Miao
BIRM 270: a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.
J Pharmacol Exp Ther December 1994 271:1418-1426
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- B E Daikh,
- J M Lasker,
- J L Raucy,
- and D R Koop
Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9.
J Pharmacol Exp Ther December 1994 271:1427-1433
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- K X Huang and
- J R Walters
Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output.
J Pharmacol Exp Ther December 1994 271:1434-1443
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- M E Reith and
- L L Coffey
Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts.
J Pharmacol Exp Ther December 1994 271:1444-1452
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- G Battaglia and
- T M Cabrera
Potentiation of 5-HT1A receptor-mediated neuroendocrine responses in male but not female rat progeny after prenatal cocaine: evidence for gender differences.
J Pharmacol Exp Ther December 1994 271:1453-1461
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- S P Zhang,
- L W Zhou,
- and B Weiss
Oligodeoxynucleotide antisense to the D1 dopamine receptor mRNA inhibits D1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine.
J Pharmacol Exp Ther December 1994 271:1462-1470
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- O Yamamoto,
- Y Matsunaga,
- Y Shiba,
- N Haga,
- I Sano,
- and Z Itoh
Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs.
J Pharmacol Exp Ther December 1994 271:1471-1476
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- B L Tepperman,
- J F Brown,
- R Korolkiewicz,
- and B J Whittle
Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge.
J Pharmacol Exp Ther December 1994 271:1477-1482
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- G Mehrke,
- X G Zong,
- V Flockerzi,
- and F Hofmann
The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels.
J Pharmacol Exp Ther December 1994 271:1483-1488
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- C A Maggi,
- M Astolfi,
- S Giuliani,
- C Goso,
- S Manzini,
- S Meini,
- R Patacchini,
- V Pavone,
- C Pedone,
- and L Quartara
MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors.
J Pharmacol Exp Ther December 1994 271:1489-1500
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- R C Pitts and
- L A Dykstra
Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.
J Pharmacol Exp Ther December 1994 271:1501-1508
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- E Yodoya,
- K Uemura,
- T Tenma,
- T Fujita,
- M Murakami,
- A Yamamoto,
- and S Muranishi
Enhanced permeability of tetragastrin across the rat intestinal membrane and its reduced degradation by acylation with various fatty acids.
J Pharmacol Exp Ther December 1994 271:1509-1513
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- P Wheelan,
- A Sala,
- G Folco,
- S Nicosia,
- J R Falck,
- R K Bhatt,
- and R C Murphy
Stereochemical analysis and biological activity of 3-hydroxy-leukotriene B4: a metabolite from ethanol-treated rat hepatocytes.
J Pharmacol Exp Ther December 1994 271:1514-1519
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- A G Shi and
- R C Deth
Precoupling of alpha-2B adrenergic receptors and G-proteins in transfected PC-12 cell membranes: influence of pertussis toxin and a lysine-directed cross-linker.
J Pharmacol Exp Ther December 1994 271:1520-1527
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- J Cleary,
- G Mikus,
- A Somogyi,
- and F Bochner
The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model.
J Pharmacol Exp Ther December 1994 271:1528-1534
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- T Kuwabara,
- Y Kato,
- S Kobayashi,
- H Suzuki,
- and Y Sugiyama
Nonlinear pharmacokinetics of a recombinant human granulocyte colony-stimulating factor derivative (nartograstim): species differences among rats, monkeys and humans.
J Pharmacol Exp Ther December 1994 271:1535-1543
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- M Thuong-Guyot,
- O Domarle,
- J J Pocidalo,
- and G Hayem
Effects of fluoroquinolones on cultured articular chondrocytes flow cytometric analysis of free radical production.
J Pharmacol Exp Ther December 1994 271:1544-1549
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- I M Khan,
- P Taylor,
- and T L Yaksh
Stimulatory pathways and sites of action of intrathecally administered nicotinic agents.
J Pharmacol Exp Ther December 1994 271:1550-1557
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- S Uhlén,
- A C Porter,
- and R R Neubig
The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors.
J Pharmacol Exp Ther December 1994 271:1558-1565
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- Z Nie,
- S G Madamba,
- and G R Siggins
Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.
J Pharmacol Exp Ther December 1994 271:1566-1573
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- T M Filtz,
- W Guan,
- R P Artymyshyn,
- M Facheco,
- C Ford,
- and P B Molinoff
Mechanisms of up-regulation of D2L dopamine receptors by agonists and antagonists in transfected HEK-293 cells.
J Pharmacol Exp Ther December 1994 271:1574-1582
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- C C Chien and
- G W Pasternak
Selective antagonism of opioid analgesia by a sigma system.
J Pharmacol Exp Ther December 1994 271:1583-1590
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- K W Hong,
- B Y Rhim,
- Y W Shin,
- and S E Yoo
Characterization of PD 121981- and CGP 42112-induced unmasking of low concentration effects of angiotensin II in rabbit abdominal aorta.
J Pharmacol Exp Ther December 1994 271:1591-1596
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- N H Chen and
- M E Reith
Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats.
J Pharmacol Exp Ther December 1994 271:1597-1610
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- G Wiemer,
- E Fink,
- W Linz,
- M Hropot,
- B E Schölkens,
- and P Wohlfart
Furosemide enhances the release of endothelial kinins, nitric oxide and prostacyclin.
J Pharmacol Exp Ther December 1994 271:1611-1615
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- A Pomés,
- E Rodríguez-Farré,
- and C Suñol
Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons.
J Pharmacol Exp Ther December 1994 271:1616-1623
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- T Watanabe and
- M Egawa
Effects of an antistroke agent MCl-186 on cerebral arachidonate cascade.
J Pharmacol Exp Ther December 1994 271:1624-1629
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- P J Emmerson,
- M R Liu,
- J H Woods,
- and F Medzihradsky
Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes.
J Pharmacol Exp Ther December 1994 271:1630-1637
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- M A Casado,
- M A Sevilla,
- M J Alonso,
- J Marin,
- and M Salaices
Muscarinic receptors involved in modulation of norepinephrine release and vasodilatation in guinea pig carotid arteries.
J Pharmacol Exp Ther December 1994 271:1638-1646
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- P A Rittenhouse,
- E A Bakkum,
- A D Levy,
- Q Li,
- M Carnes,
- and L D van de Kar
Evidence that ACTH secretion is regulated by serotonin2A/2C (5-HT2A/2C) receptors.
J Pharmacol Exp Ther December 1994 271:1647-1655
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- P Guillaume,
- J Gutkowska,
- and C Gianoulakis
Increased plasma atrial natriuretic peptide after acute injection of alcohol in rats.
J Pharmacol Exp Ther December 1994 271:1656-1665
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- S Matzno,
- M Gohda,
- M Eda,
- H Ebisu,
- S Uno,
- N Ishida,
- N Nakamura,
- and K Yamanouchi
A possible mechanism of action of a new potassium channel opener, AL0671, on lipid metabolism in obese Zucker rats.
J Pharmacol Exp Ther December 1994 271:1666-1671
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- R Igarashi,
- J Hoshino,
- A Ochiai,
- Y Morizawa,
- and Y Mizushima
Lecithinized superoxide dismutase enhances its pharmacologic potency by increasing its cell membrane affinity.
J Pharmacol Exp Ther December 1994 271:1672-1677
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- J K Staley,
- W L Hearn,
- A J Ruttenber,
- C V Wetli,
- and D C Mash
High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims.
J Pharmacol Exp Ther December 1994 271:1678-1685
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- P Y Law,
- T M McGinn,
- M J Wick,
- L J Erikson,
- C Evans,
- and H H Loh
Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density?
J Pharmacol Exp Ther December 1994 271:1686-1694
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- L M Kamendulis and
- G B Corcoran
DNA as a critical target in toxic cell death: enhancement of dimethylnitrosamine cytotoxicity by DNA repair inhibitors.
J Pharmacol Exp Ther December 1994 271:1695-1698
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- G E Duncan,
- D J Knapp,
- K Y Little,
- and G R Breese
Neuroanatomical specificity and dose dependence in the time course of imipramine-induced beta adrenergic receptor down-regulation in rat brain.
J Pharmacol Exp Ther December 1994 271:1699-1704
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- P Patrignani,
- M R Panara,
- A Greco,
- O Fusco,
- C Natoli,
- S Iacobelli,
- F Cipollone,
- A Ganci,
- C Créminon,
- and J Maclouf
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases.
J Pharmacol Exp Ther December 1994 271:1705-1712
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- J Y Lee,
- Y Uchida,
- T Sakamoto,
- A Hirata,
- S Hasegawa,
- and F Hirata
Alteration of G protein levels in antigen-challenged guinea pigs.
J Pharmacol Exp Ther December 1994 271:1713-1720
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J Pharmacol Exp Ther December 1994 271:1720
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Current Issue

November 2009, 331 (2)

Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.

Chronic nicotine administration does not affect peripheral vascular reactivity in the rat.

Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor.

Acute effects of ethanol on cardiac output and its derivatives in spontaneously hypertensive and normotensive rats.

Isoflurane reduces Ca++ channel current and accelerates current decay in guinea pig portal vein smooth muscle cells.

Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoceptor agonist albuterol.

Ethanol-induced depressions of cerebellar Purkinje neurons are potentiated by beta-adrenergic mechanisms in rat brain.

Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors.

Haloperidol-induced behavioral supersensitivity is increased by monosialoganglioside treatment in rats without affecting spiroperidol-binding.

Blood-brain barrier permeability and in vivo activity of partial agonists of benzodiazepine receptor: a study of L-663,581 and its metabolites in rats.

Cyclic GMP but not cyclic AMP prevents renal platelet accumulation after ischemia-reperfusion in anesthetized rats.

Electrophysiological and radioligand binding studies of elgodipine and derivatives in portal vein myocytes.

GBR12909 attenuates cocaine-induced activation of mesolimbic dopamine neurons in the rat.

Inhibition by nickel of endothelin-1-induced tension and associated 45Ca movements in rabbit aorta.

Characterization of alpha-1 adrenoceptor subtypes in human and canine prostate membranes.

Maternal and fetal brain and plasma levels of cocaine and benzoylecgonine after acute or chronic maternal intravenous administration of cocaine.

Inhibition of insulin release by a formamidine pesticide amitraz and its metabolites in a rat beta-cell line: an action mediated by alpha-2 adrenoceptors, a GTP-binding protein and a decrease in cyclic AMP.

Differential receptor reserve for 5-HT1A receptor-mediated regulation of plasma neuroendocrine hormones.

Influence of cell type upon the desensitization of the beta 3-adrenergic receptor.

Unmasking of activated histamine H3-receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release.

Antitumor activity of a medium-chain triglyceride solution of the angiogenesis inhibitor TNP-470 (AGM-1470) when administered via the hepatic artery to rats bearing Walker 256 carcinosarcoma in the liver.

Alkylglycosides enhance systemic absorption of insulin applied topically to the rat eye.

Substance P N-terminal metabolites and nitric oxide mediate capsaicin-induced antinociception in the adult mouse.

Decreased intracellular compartmentalization of doxorubicin in cell lines expressing P-glycoprotein.

Effects of prenatal ethanol exposure on N-methyl-D-aspartate-mediated calcium entry into dissociated neurons.

Neonatal hypoxia: early neurotransmitter responses and the consequences of treatment with GM1 ganglioside.

Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50,488H against noxious thermal, mechanical and inflammatory stimuli.

Alaproclate acts as a potent, reversible and noncompetitive antagonist of the NMDA receptor coupled ion flow.

Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.

Transport of cefadroxil in rat kidney brush-border membranes is mediated by two electrogenic H+-coupled systems.

Antihypertensive effects of metformin in fructose-fed hyperinsulinemic, hypertensive rats.

In the search for a novel class of antipsychotic drugs: preclinical pharmacology of FG5803, a 1-piperazinecarboxamide derivative.

Effects of a new class of calcium antagonists, SR33557 (fantofarone) and SR33805, on neuronal voltage-activated Ca++ channels.

Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.

Ca++ mobilization mediated by endothelin ETA receptor in endothelium of rabbit aortic valve.

Involvement of NMDA receptors in naloxone-induced contractions of the isolated guinea pig ileum after preincubation with morphine.

The cardiac effects of a novel A1-adenosine receptor agonist in guinea pig isolated heart.

Development of cross-tolerance between delta 9-tetrahydrocannabinol, CP 55,940 and WIN 55,212.

Relative sensitivity to naloxone of multiple indices of opiate withdrawal: a quantitative dose-response analysis.

Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.

Effects of felodipine on left ventricular systolic and diastolic performance in congestive heart failure.

BIRM 270: a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils.

Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9.

Electrophysiological effects of SKF 38393 in rats with reserpine treatment and 6-hydroxydopamine-induced nigrostriatal lesions reveal two types of plasticity in D1 dopamine receptor modulation of basal ganglia output.

Structure-activity relationships for cocaine congeners in inhibiting dopamine uptake into rat brain synaptic vesicles and bovine chromaffin granule ghosts.

Potentiation of 5-HT1A receptor-mediated neuroendocrine responses in male but not female rat progeny after prenatal cocaine: evidence for gender differences.

Oligodeoxynucleotide antisense to the D1 dopamine receptor mRNA inhibits D1 dopamine receptor-mediated behaviors in normal mice and in mice lesioned with 6-hydroxydopamine.

Inhibition of motilin-induced phase III contractions by pentagastrin in Heidenhain pouch dogs.

Nitric oxide synthase activity, viability and cyclic GMP levels in rat colonic epithelial cells: effect of endotoxin challenge.

The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels.

MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors.

Antinociceptive and response rate-altering effects of kappa opioid agonists, spiradoline, enadoline and U69,593, alone and in combination with opioid antagonists in squirrel monkeys.

Enhanced permeability of tetragastrin across the rat intestinal membrane and its reduced degradation by acylation with various fatty acids.

Stereochemical analysis and biological activity of 3-hydroxy-leukotriene B4: a metabolite from ethanol-treated rat hepatocytes.

Precoupling of alpha-2B adrenergic receptors and G-proteins in transfected PC-12 cell membranes: influence of pertussis toxin and a lysine-directed cross-linker.

The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model.

Nonlinear pharmacokinetics of a recombinant human granulocyte colony-stimulating factor derivative (nartograstim): species differences among rats, monkeys and humans.

Effects of fluoroquinolones on cultured articular chondrocytes flow cytometric analysis of free radical production.

Stimulatory pathways and sites of action of intrathecally administered nicotinic agents.

The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors.

Ethanol inhibits glutamatergic neurotransmission in nucleus accumbens neurons by multiple mechanisms.

Mechanisms of up-regulation of D2L dopamine receptors by agonists and antagonists in transfected HEK-293 cells.

Selective antagonism of opioid analgesia by a sigma system.

Characterization of PD 121981- and CGP 42112-induced unmasking of low concentration effects of angiotensin II in rabbit abdominal aorta.

Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine: a microdialysis study in freely moving rats.

Furosemide enhances the release of endothelial kinins, nitric oxide and prostacyclin.

Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons.

Effects of an antistroke agent MCl-186 on cerebral arachidonate cascade.

Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes.

Muscarinic receptors involved in modulation of norepinephrine release and vasodilatation in guinea pig carotid arteries.

Evidence that ACTH secretion is regulated by serotonin2A/2C (5-HT2A/2C) receptors.

Increased plasma atrial natriuretic peptide after acute injection of alcohol in rats.

A possible mechanism of action of a new potassium channel opener, AL0671, on lipid metabolism in obese Zucker rats.

Lecithinized superoxide dismutase enhances its pharmacologic potency by increasing its cell membrane affinity.

High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims.

Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density?

DNA as a critical target in toxic cell death: enhancement of dimethylnitrosamine cytotoxicity by DNA repair inhibitors.

Neuroanatomical specificity and dose dependence in the time course of imipramine-induced beta adrenergic receptor down-regulation in rat brain.

Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases.