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Table of Contents
November 1994; 271 (2)
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M A Simmons
,
C R Schneider
,
and
J E Krause
Regulation of the responses to gonadotropin-releasing hormone, muscarine and substance P in sympathetic neurons by changes in cellular constituents and intracellular application of peptide fragments of the substance P receptor.
J Pharmacol Exp Ther
November 1994
271
:
581
-
589
Abstract
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B Yu
and
P Shinnick-Gallagher
Interleukin-1 beta inhibits synaptic transmission and induces membrane hyperpolarization in amygdala neurons.
J Pharmacol Exp Ther
November 1994
271
:
590
-
600
Abstract
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E T Iwamoto
and
L Marion
Pharmacologic evidence that spinal muscarinic analgesia is mediated by an L-arginine/nitric oxide/cyclic GMP cascade in rats.
J Pharmacol Exp Ther
November 1994
271
:
601
-
608
Abstract
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A Asplund
,
D Grant
,
and
J O Karlsson
Mangafodipir (MnDPDP)-and MnCl2-induced endothelium-dependent relaxation in bovine mesenteric arteries.
J Pharmacol Exp Ther
November 1994
271
:
609
-
614
Abstract
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E W Jonsson
and
S E Dahlén
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
J Pharmacol Exp Ther
November 1994
271
:
615
-
623
Abstract
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J P Sullivan
,
M W Decker
,
J D Brioni
,
D Donnelly-Roberts
,
D J Anderson
,
A W Bannon
,
C H Kang
,
P Adams
,
M Piattoni-Kaplan
,
and
M J Buckley
(+/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors.
J Pharmacol Exp Ther
November 1994
271
:
624
-
631
Abstract
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K Kon
,
E Krause
,
and
H Gögelein
Inhibition of K+ channels by chlorpromazine in rat ventricular myocytes.
J Pharmacol Exp Ther
November 1994
271
:
632
-
637
Abstract
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G Mittleman
,
A L Rosner
,
and
C L Schaub
Polydipsia and dopamine: behavioral effects of dopamine D1 and D2 receptor agonists and antagonists.
J Pharmacol Exp Ther
November 1994
271
:
638
-
650
Abstract
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X Yang
and
J J Buccafusco
Effect of chronic central treatment with the acetylcholine analog methylcarbamylcholine on cortical nicotinic receptors: correlation between receptor changes and behavioral function.
J Pharmacol Exp Ther
November 1994
271
:
651
-
659
Abstract
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M Orihata
and
S K Sarna
Inhibition of nitric oxide synthase delays gastric emptying of solid meals.
J Pharmacol Exp Ther
November 1994
271
:
660
-
670
Abstract
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J K Williams
,
Y D Kim
,
M R Adams
,
M F Chen
,
A K Myers
,
and
P W Ramwell
Effects of estrogen on cardiovascular responses of premenopausal monkeys.
J Pharmacol Exp Ther
November 1994
271
:
671
-
676
Abstract
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R P Irwin
,
S Z Lin
,
M A Rogawski
,
R H Purdy
,
and
S M Paul
Steroid potentiation and inhibition of N-methyl-D-aspartate receptor-mediated intracellular Ca++ responses: structure-activity studies.
J Pharmacol Exp Ther
November 1994
271
:
677
-
682
Abstract
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S M Evans
,
J R Troisi, 2nd
,
and
R R Griffiths
Tandospirone and alprazolam: comparison of behavioral effects and abuse liability in humans.
J Pharmacol Exp Ther
November 1994
271
:
683
-
694
Abstract
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K Kuratani
,
H Kodama
,
and
I Yamaguchi
The differential roles of sympathetic nerve activity in the pathogenesis of antral and corpus lesions induced by indomethacin in rats.
J Pharmacol Exp Ther
November 1994
271
:
695
-
702
Abstract
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M Sugiura
,
Y Shoyama
,
H Saito
,
and
K Abe
Crocin (crocetin di-gentiobiose ester) prevents the inhibitory effect of ethanol on long-term potentiation in the dentate gyrus in vivo.
J Pharmacol Exp Ther
November 1994
271
:
703
-
707
Abstract
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J J McGuire
,
D J Anderson
,
and
B M Bennett
Inhibition of the biotransformation and pharmacological actions of glyceryl trinitrate by the flavoprotein inhibitor, diphenyleneiodonium sulfate.
J Pharmacol Exp Ther
November 1994
271
:
708
-
714
Abstract
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T F Burke
,
J H Woods
,
J W Lewis
,
and
F Medzihradsky
Irreversible opioid antagonist effects of clocinnamox on opioid analgesia and mu receptor binding in mice.
J Pharmacol Exp Ther
November 1994
271
:
715
-
721
Abstract
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W J Wu
,
R M Wolcott
,
and
S B Pruett
Ethanol decreases the number and activity of splenic natural killer cells in a mouse model for binge drinking.
J Pharmacol Exp Ther
November 1994
271
:
722
-
729
Abstract
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N J Lodge
Direct vasoconstrictor effects of sandimmune (cyclosporine A) are mediated by its vehicle cremophor EL: inhibition by the thromboxane A2/prostaglandin endoperoxide receptor antagonist ifetroban.
J Pharmacol Exp Ther
November 1994
271
:
730
-
734
Abstract
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M F O'Rourke
,
L J Iversen
,
J W Lomasney
,
and
D B Bylund
Species orthologs of the alpha-2A adrenergic receptor: the pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors.
J Pharmacol Exp Ther
November 1994
271
:
735
-
740
Abstract
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S S Hedge
,
T M Moy
,
M R Perry
,
M Loeb
,
and
R M Eglen
Evidence for the involvement of 5-hydroxytryptamine 4 receptors in 5-hydroxytryptophan-induced diarrhea in mice.
J Pharmacol Exp Ther
November 1994
271
:
741
-
747
Abstract
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H M Vargas
,
L Zhou
,
and
A J Gorman
Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat.
J Pharmacol Exp Ther
November 1994
271
:
748
-
754
Abstract
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P Nambi
,
N Elshourbagy
,
H L Wu
,
M Pullen
,
E H Ohlstein
,
D P Brooks
,
M A Lago
,
J D Elliott
,
J G Gleason
,
and
R R Ruffolo, Jr
Nonpeptide endothelin receptor antagonists. I. Effects on binding and signal transduction on human endothelinA and endothelinB receptors.
J Pharmacol Exp Ther
November 1994
271
:
755
-
761
Abstract
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E H Ohlstein
,
G R Beck, Jr
,
S A Douglas
,
P Nambi
,
M A Lago
,
J G Gleason
,
R R Ruffolo, Jr
,
G Feuerstein
,
and
J D Elliott
Nonpeptide endothelin receptor antagonists. II. Pharmacological characterization of SB 209670.
J Pharmacol Exp Ther
November 1994
271
:
762
-
768
Abstract
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D P Brooks
,
P D dePalma
,
M Gellai
,
P Nambi
,
E H Ohlstein
,
J D Elliott
,
J G Gleason
,
and
R R Ruffolo, Jr
Nonpeptide endothelin receptor antagonists. III. Effect of SB 209670 and BQ123 on acute renal failure in anesthetized dogs.
J Pharmacol Exp Ther
November 1994
271
:
769
-
775
Abstract
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R B McCall
,
N A Escandon
,
L T Harris
,
and
M E Clement
Tolerance development to the vagal-mediated bradycardia produced by 5-HT1A receptor agonists.
J Pharmacol Exp Ther
November 1994
271
:
776
-
781
Abstract
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J L Ellis
and
N D Conanan
Effect of potassium channel blockers on relaxations to a nitric oxide donor and to nonadrenergic nerve stimulation in guinea pig trachea.
J Pharmacol Exp Ther
November 1994
271
:
782
-
786
Abstract
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V P Bakshi
,
N R Swerdlow
,
and
M A Geyer
Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response.
J Pharmacol Exp Ther
November 1994
271
:
787
-
794
Abstract
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M W Lutz
,
P H Morgan
,
M K James
,
P L Feldman
,
M F Brackeen
,
A P Lahey
,
S V James
,
J M Bilotta
,
and
J C Pressley
A pharmacodynamic model to investigate the structure-activity profile of a series of novel opioid analgesics.
J Pharmacol Exp Ther
November 1994
271
:
795
-
803
Abstract
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V J Gorbea-Oppliger
,
M G Melaragno
,
G S Potter
,
R L Petit
,
and
G D Fink
Time course of losartan blockade of angiotensin II hypertension versus blockade of angiotensin II fast pressor effects.
J Pharmacol Exp Ther
November 1994
271
:
804
-
810
Abstract
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B J Undem
,
S N Meeker
,
and
J Chen
Inhibition of neurally mediated nonadrenergic, noncholinergic contractions of guinea pig bronchus by isozyme-selective phosphodiesterase inhibitors.
J Pharmacol Exp Ther
November 1994
271
:
811
-
817
Abstract
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X Gao
,
C A Buffington
,
and
J L Au
Effect of interstitial cystitis on drug absorption from urinary bladder.
J Pharmacol Exp Ther
November 1994
271
:
818
-
823
Abstract
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M R James-Kracke
,
R B Sexe
,
and
S D Shukla
Picomolar platelet-activating factor mobilizes Ca to change platelet shape without activating phospholipase C or protein kinase C; simultaneous fluorometric measurement of intracellular free Ca concentration and aggregation.
J Pharmacol Exp Ther
November 1994
271
:
824
-
831
Abstract
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S W Watts
,
D A Cox
,
B G Johnson
,
D D Schoepp
,
and
M L Cohen
Contractile serotonin-2A receptor signal transduction in guinea pig trachea: importance of protein kinase C and extracellular and intracellular calcium but not phosphoinositide hydrolysis.
J Pharmacol Exp Ther
November 1994
271
:
832
-
844
Abstract
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J C Wanstall
In vitro hypoxia attenuates vasorelaxation by potassium channel opening drugs and nitroprusside in isolated pulmonary arteries from rats.
J Pharmacol Exp Ther
November 1994
271
:
845
-
851
Abstract
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K M Tramposch
,
F H Chilton
,
P L Stanley
,
R C Franson
,
M B Havens
,
D O Nettleton
,
L B Davern
,
I M Darling
,
and
R J Bonney
Inhibitor of phospholipase A2 blocks eicosanoid and platelet activating factor biosynthesis and has topical anti-inflammatory activity.
J Pharmacol Exp Ther
November 1994
271
:
852
-
859
Abstract
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E Koyama
,
D R Sohn
,
S G Shin
,
K Chiba
,
J G Shin
,
Y H Kim
,
H Echizen
,
and
T Ishizaki
Metabolic disposition of imipramine in oriental subjects: relation to metoprolol alpha-hydroxylation and S-mephenytoin 4'-hydroxylation phenotypes.
J Pharmacol Exp Ther
November 1994
271
:
860
-
867
Abstract
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E V Mishina
,
J Binder
,
J W Kupiec-Weglinski
,
and
W J Jusko
Effect of liposomal methylprednisolone on heart allograft survival and immune function in rats.
J Pharmacol Exp Ther
November 1994
271
:
868
-
874
Abstract
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R B McCall
,
A G Romero
,
M J Bienkowski
,
D W Harris
,
J C McGuire
,
M F Piercey
,
M E Shuck
,
M W Smith
,
K A Svensson
,
and
P J Schreur
Characterization of U-92016A as a selective, orally active, high intrinsic activity 5-hydroxytryptamine1A agonist.
J Pharmacol Exp Ther
November 1994
271
:
875
-
883
Abstract
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Y Itoh
,
T Ogasawara
,
T Mushiroi
,
A yamazaki
,
Y Ukai
,
and
K Kimura
Effect of NS-3, a thyrotropin-releasing hormone analog, on in vivo acetylcholine release in rat brain: regional differences and its sites of action.
J Pharmacol Exp Ther
November 1994
271
:
884
-
890
Abstract
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C M Maciag
,
A R Logue
,
W J Tinker
,
J A Saydoff
,
S W Tam
,
and
R Zaczek
Studies on the role of K+, Cl- and Na+ ion permeabilities in the acetylcholine release enhancing effects of linopirdine (DuP 996) in rat cortical slices.
J Pharmacol Exp Ther
November 1994
271
:
891
-
897
Abstract
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T K Machu
and
R A Harris
Alcohols and anesthetics enhance the function of 5-hydroxytryptamine3 receptors expressed in Xenopus laevis oocytes.
J Pharmacol Exp Ther
November 1994
271
:
898
-
905
Abstract
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J R Hammond
Functional reconstitution of pharmacologically distinct subtypes of nucleoside transporters in liposomal membranes.
J Pharmacol Exp Ther
November 1994
271
:
906
-
917
Abstract
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L M Hryhorenko
,
Z Woskowska
,
and
J A Fox-Threlkeld
Nitric oxide (NO) inhibits release of acetylcholine from nerves of isolated circular muscle of the canine ileum: relationship to motility and release of nitric oxide.
J Pharmacol Exp Ther
November 1994
271
:
918
-
926
Abstract
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O Laneuville
,
D K Breuer
,
D L Dewitt
,
T Hla
,
C D Funk
,
and
W L Smith
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs.
J Pharmacol Exp Ther
November 1994
271
:
927
-
934
Abstract
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Q Y Liu
,
E Karpinski
,
and
P K Pang
The L-type calcium channel current is increased by alpha-1 adrenoceptor activation in neonatal rat ventricular cells.
J Pharmacol Exp Ther
November 1994
271
:
935
-
943
Abstract
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Q Y Liu
,
E Karpinski
,
and
P K Pang
L-channel modulation by alpha-1 adrenoceptor activation in neonatal rat ventricular cells: intracellular mechanisms.
J Pharmacol Exp Ther
November 1994
271
:
944
-
951
Abstract
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C B Unal
,
M D Owen
,
and
W R Millington
Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.
J Pharmacol Exp Ther
November 1994
271
:
952
-
958
Abstract
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E A Walker
,
M M Makhay
,
J D House
,
and
A M Young
In vivo apparent pA2 analysis for naltrexone antagonism of discriminative stimulus and analgesic effects of opiate agonists in rats.
J Pharmacol Exp Ther
November 1994
271
:
959
-
968
Abstract
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B Hitzemann
,
K Dains
,
S Kanes
,
and
R Hitzemann
Further studies on the relationship between dopamine cell density and haloperidol-induced catalepsy.
J Pharmacol Exp Ther
November 1994
271
:
969
-
976
Abstract
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S Zalcman
,
J M Green-Johnson
,
L Murray
,
W Wan
,
D M Nance
,
and
A H Greenberg
Interleukin-2-induced enhancement of an antigen-specific IgM plaque-forming cell response is mediated by the sympathetic nervous system.
J Pharmacol Exp Ther
November 1994
271
:
977
-
982
Abstract
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E Sehic
,
Y Ruan
,
and
K U Malik
Attenuation by alpha,beta-methylenadenosine-5'-triphosphate of periarterial nerve stimulation-induced renal vasoconstriction is not due to desensitization of purinergic receptors.
J Pharmacol Exp Ther
November 1994
271
:
983
-
992
Abstract
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L R Gerak
,
E R Butelman
,
J H Woods
,
and
C P France
Antinociceptive and respiratory effects of nalbuphine in rhesus monkeys.
J Pharmacol Exp Ther
November 1994
271
:
993
-
999
Abstract
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J L Goudreau
,
E J Wagner
,
K J Lookingland
,
and
K E Moore
gamma-Aminobutyric acid receptor-mediated regulation of periventricular-hypophysial dopaminergic neurons: possible role in mediating stress- and 5-hydroxytryptamine-induced decreases in neuronal activity.
J Pharmacol Exp Ther
November 1994
271
:
1000
-
1006
Abstract
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G A Knock
,
M H Sullivan
,
A McCarthy
,
M G Elder
,
J M Polak
,
and
J Wharton
Angiotensin II (AT1) vascular binding sites in human placentae from normal-term, preeclamptic and growth retarded pregnancies.
J Pharmacol Exp Ther
November 1994
271
:
1007
-
1015
Abstract
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P K Rangachari
and
T Prior
Functional subtyping of histamine receptors on the canine proximal colonic mucosa.
J Pharmacol Exp Ther
November 1994
271
:
1016
-
1026
Abstract
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S Takano
,
S Gately
,
J B Jiang
,
and
S Brem
A diaminoantraquinone inhibitor of angiogenesis.
J Pharmacol Exp Ther
November 1994
271
:
1027
-
1033
Abstract
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D D D'Angelo
,
M G Davis
,
S Ali
,
and
G W Dorn, 2nd
Cloning and pharmacologic characterization of a thromboxane A2 receptor from K562 (human chronic myelogenous leukemia) cells.
J Pharmacol Exp Ther
November 1994
271
:
1034
-
1041
Abstract
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E A Thomas
and
F J Ehlert
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis.
J Pharmacol Exp Ther
November 1994
271
:
1042
-
1050
Abstract
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S M Roberts
,
R D Harbison
,
and
R C James
Methamphetamine potentiation of carbon tetrachloride hepatotoxicity in mice.
J Pharmacol Exp Ther
November 1994
271
:
1051
-
1057
Abstract
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G S Robertson
,
H Matsumura
,
and
H C Fibiger
Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity.
J Pharmacol Exp Ther
November 1994
271
:
1058
-
1066
Abstract
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N A Pampori
and
B H Shapiro
Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats neonatally exposed to low levels of monosodium glutamate.
J Pharmacol Exp Ther
November 1994
271
:
1067
-
1073
Abstract
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H Farrington
,
F Mendelsohn
,
S Chan
,
L Reinlib
,
and
S E Guggino
Strychnine-binding proteins in intestinal cells: novel brucine binding site with binding affinities for alkaloids.
J Pharmacol Exp Ther
November 1994
271
:
1074
-
1079
Abstract
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C J Kirk
,
N L Reddy
,
J B Fischer
,
T C Wolcott
,
A G Knapp
,
and
R N McBurney
In vitro neuroprotection by substituted guanidines with varying affinities for the N-methyl-D-aspartate receptor ionophore and for sigma sites.
J Pharmacol Exp Ther
November 1994
271
:
1080
-
1085
Abstract
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P M Lacal
,
A Puglianiello
,
E Bonmassar
,
and
C D'Onofrio
Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. I. Cell differentiation determines sensitivity to prostaglandins and virus infection.
J Pharmacol Exp Ther
November 1994
271
:
1086
-
1095
Abstract
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P M Lacal
,
C Amici
,
E Bonmassar
,
and
C D'Onofrio
Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV-I. II. Regulation of synthesis of inducible p72 heat shock protein.
J Pharmacol Exp Ther
November 1994
271
:
1096
-
1102
Abstract
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C A Branch
and
M M Knuepfer
Causes of differential cardiovascular sensitivity to cocaine. II: Sympathetic, metabolic and cardiac effects.
J Pharmacol Exp Ther
November 1994
271
:
1103
-
1113
Abstract
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M B Grisham
,
R D Specian
,
and
T E Zimmerman
Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis.
J Pharmacol Exp Ther
November 1994
271
:
1114
-
1121
Abstract
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M S Grotewiel
,
H Chu
,
and
E Sanders-Bush
m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine are partial agonists at cloned 5-HT2A receptors expressed in fibroblasts.
J Pharmacol Exp Ther
November 1994
271
:
1122
-
1126
Abstract
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