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Table of Contents
September 1994; 270 (3)
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W C Duane
Effects of lovastatin in humans on biliary lipid composition and secretion as a function of dosage and treatment interval.
J Pharmacol Exp Ther
September 1994
270
:
841
-
845
Abstract
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P J Riviere
,
X Pascaud
,
E Chevalier
,
and
J L Junien
Fedotozine reversal of peritoneal-irritation-induced ileus in rats: possible peripheral action on sensory afferents.
J Pharmacol Exp Ther
September 1994
270
:
846
-
850
Abstract
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Y N Cheng
,
T Kiyosue
,
and
M Arita
Effects of KT-362, a new antiarrhythmic agent, on membrane ionic currents of guinea pig ventricular myocytes.
J Pharmacol Exp Ther
September 1994
270
:
851
-
857
Abstract
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J A Awad
,
R F Burk
,
and
L J Roberts, 2nd
Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats.
J Pharmacol Exp Ther
September 1994
270
:
858
-
864
Abstract
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J P Uetrecht
,
N Zahid
,
and
D Whitfield
Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis.
J Pharmacol Exp Ther
September 1994
270
:
865
-
872
Abstract
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B M Tune
and
C Y Hsu
Toxicity of cephaloridine to carnitine transport and fatty acid metabolism in rabbit renal cortical mitochondria: structure-activity relationships.
J Pharmacol Exp Ther
September 1994
270
:
873
-
880
Abstract
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K Yamada
,
S Nakayama
,
T Shiotani
,
T Hasegawa
,
and
T Nabeshima
Possible involvement of the activation of voltage-sensitive calcium channels in the ameliorating effects of nefiracetam on scopolamine-induced impairment of performance in a passive avoidance task.
J Pharmacol Exp Ther
September 1994
270
:
881
-
892
Abstract
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P L Martin
and
A A Potts
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
J Pharmacol Exp Ther
September 1994
270
:
893
-
899
Abstract
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T H Chen
,
B Lee
,
and
W H Hsu
Arginine vasopressin-stimulated insulin secretion and elevation of intracellular Ca++ concentration in rat insulinoma cells: influences of a phospholipase C inhibitor 1-[6-[[17 beta-methoxyestra-1,3,5(10)-trien- 17-yl]amino]hexyl]-1H-pyrrole-2,5-dione (U-73122) and a phospholipase A2 inhibitor N-(p-amylcinnamoyl)anthranilic acid.
J Pharmacol Exp Ther
September 1994
270
:
900
-
904
Abstract
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D Saphier
and
J E Welch
Central stimulation of adrenocortical secretion by 5-hydroxytryptamine1A agonists is mediated by sympathomedullary activation.
J Pharmacol Exp Ther
September 1994
270
:
905
-
917
Abstract
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J E Welch
and
D Saphier
Central and peripheral mechanisms in the stimulation of adrenocortical secretion by the 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane.
J Pharmacol Exp Ther
September 1994
270
:
918
-
928
Abstract
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R Ciccocioppo
,
L Onori
,
E Messori
,
S M Candura
,
T Coccini
,
and
M Tonini
Role of nitric oxide-dependent and -independent mechanisms in peristalsis and accommodation in the rabbit distal colon.
J Pharmacol Exp Ther
September 1994
270
:
929
-
937
Abstract
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P J Pauwels
and
C Palmier
Differential functional activity of 5-hydroxytryptamine receptor ligands and beta adrenergic receptor antagonists at 5-hydroxytryptamine1B receptor sites in Chinese hamster lung fibroblasts and opossum renal epithelial cells.
J Pharmacol Exp Ther
September 1994
270
:
938
-
945
Abstract
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A Renouard
,
P S Widdowson
,
and
M J Millan
Multiple alpha 2 adrenergic receptor subtypes. I. Comparison of [3H]RX821002-labeled rat R alpha-2A adrenergic receptors in cerebral cortex to human H alpha2A adrenergic receptor and other populations of alpha-2 adrenergic subtypes.
J Pharmacol Exp Ther
September 1994
270
:
946
-
957
Abstract
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M J Millan
,
K Bervoets
,
J M Rivet
,
P Widdowson
,
A Renouard
,
S Le Marouille-Girardon
,
and
A Gobert
Multiple alpha-2 adrenergic receptor subtypes. II. Evidence for a role of rat R alpha-2A adrenergic receptors in the control of nociception, motor behavior and hippocampal synthesis of noradrenaline.
J Pharmacol Exp Ther
September 1994
270
:
958
-
972
Abstract
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M Breuiller-Fouché
,
V Héluy
,
T Fournier
,
and
F Ferré
Endothelin receptors: binding and phosphoinositide breakdown in human myometrium.
J Pharmacol Exp Ther
September 1994
270
:
973
-
978
Abstract
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M R Escorbar
,
L T Wong
,
and
D S Sitar
Bicarbonate-dependent amantadine transport by rat renal cortical proximal and distal tubules.
J Pharmacol Exp Ther
September 1994
270
:
979
-
986
Abstract
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S A Zimmerman
,
M V Jones
,
and
N L Harrison
Potentiation of gamma-aminobutyric acidA receptor Cl- current correlates with in vivo anesthetic potency.
J Pharmacol Exp Ther
September 1994
270
:
987
-
991
Abstract
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C P France
and
L R Gerak
Behavioral effects of 6-methylene naltrexone (nalmefene) in rhesus monkeys.
J Pharmacol Exp Ther
September 1994
270
:
992
-
999
Abstract
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A Giovanni
,
B A Sieber
,
R E Heikkila
,
and
P K Sonsalla
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration.
J Pharmacol Exp Ther
September 1994
270
:
1000
-
1007
Abstract
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A Giovanni
,
P K Sonsalla
,
and
R E Heikkila
Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 2: Central administration of 1-methyl-4-phenylpyridinium.
J Pharmacol Exp Ther
September 1994
270
:
1008
-
1014
Abstract
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K A Criswell
,
E L Stuenkel
,
and
R Loch-Caruso
Lindane increases intracellular calcium in rat myometrial smooth muscle cells through modulation of inositol 1,4,5-trisphosphate-sensitive stores.
J Pharmacol Exp Ther
September 1994
270
:
1015
-
1024
Abstract
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S S Negus
,
E R Butelman
,
K J Chang
,
B DeCosta
,
G Winger
,
and
J H Woods
Behavioral effects of the systemically active delta opioid agonist BW373U86 in rhesus monkeys.
J Pharmacol Exp Ther
September 1994
270
:
1025
-
1034
Abstract
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S Ozaki
,
M Ihara
,
T Saeki
,
T Fukami
,
K Ishikawa
,
and
M Yano
Endothelin ETB receptors couple to two distinct signaling pathways in porcine kidney epithelial LLC-PK1 cells.
J Pharmacol Exp Ther
September 1994
270
:
1035
-
1040
Abstract
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P Terry
,
J M Witkin
,
and
J L Katz
Pharmacological characterization of the novel discriminative stimulus effects of a low dose of cocaine.
J Pharmacol Exp Ther
September 1994
270
:
1041
-
1048
Abstract
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K E Vanover
and
W L Woolverton
Behavioral effects of the dopamine autoreceptor agonist PD 128483 alone and in combination with cocaine.
J Pharmacol Exp Ther
September 1994
270
:
1049
-
1056
Abstract
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A Keshavarzian
,
O Zorub
,
M Sayeed
,
G Urban
,
C Sweeney
,
D Winship
,
and
J Fields
Acute ethanol inhibits calcium influxes into esophageal smooth but not striated muscle: a possible mechanism for ethanol-induced inhibition of esophageal contractility.
J Pharmacol Exp Ther
September 1994
270
:
1057
-
1062
Abstract
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C K Kost, Jr
,
P Li
,
C A Pfeifer
,
and
E K Jackson
Telemetric blood pressure monitoring in benign 2-kidney, 1-clip renovascular hypertension: effect of chronic caffeine ingestion.
J Pharmacol Exp Ther
September 1994
270
:
1063
-
1070
Abstract
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J C Hartman
,
G M Kurc
,
T G Hullinger
,
T M Wall
,
R M Sheehy
,
and
R J Shebuski
Inhibition of nitric oxide synthase prevents myocardial protection by ramiprilat.
J Pharmacol Exp Ther
September 1994
270
:
1071
-
1076
Abstract
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S Greenberg
,
C McGowan
,
J Xie
,
and
W R Summer
Selective pulmonary and venous smooth muscle relaxation by furosemide: a comparison with morphine.
J Pharmacol Exp Ther
September 1994
270
:
1077
-
1085
Abstract
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J E Zadina
,
L M Harrison
,
L J Ge
,
A J Kastin
,
and
S L Chang
Differential regulation of mu and delta opiate receptors by morphine, selective agonists and antagonists and differentiating agents in SH-SY5Y human neuroblastoma cells.
J Pharmacol Exp Ther
September 1994
270
:
1086
-
1096
Abstract
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F Courjault-Gautier
,
D Hoet
,
D Leroy
,
and
H J Toutain
Dissimilar alterations of sodium-coupled uptake by platinum-coordination complexes in renal proximal tubular cells in primary culture.
J Pharmacol Exp Ther
September 1994
270
:
1097
-
1104
Abstract
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J W Karanian
,
H Y Kim
,
and
N Salem, Jr
Inhibitory effects of n-6 and n-3 hydroxy fatty acids on thromboxane (U46619)-induced smooth muscle contraction.
J Pharmacol Exp Ther
September 1994
270
:
1105
-
1109
Abstract
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N K Mello
,
J H Mendelson
,
J M Drieze
,
S K Teoh
,
M L Kelly
,
and
J W Sholar
Effects of dopamine on prolactin: interactions with cocaine self-administration by female rhesus monkeys.
J Pharmacol Exp Ther
September 1994
270
:
1110
-
1120
Abstract
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L Fernández
,
L D Boada
,
O P Luzardo
,
M Zumbado
,
J C Díaz-Chico
,
B N Díaz-Chico
,
and
R Chirino
Ethinylestradiol interacts with liver microsomes and induces binding sites for steroid hormones in the male rat liver.
J Pharmacol Exp Ther
September 1994
270
:
1121
-
1126
Abstract
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D O Freier
and
B A Fuchs
A mechanism of action for morphine-induced immunosuppression: corticosterone mediates morphine-induced suppression of natural killer cell activity.
J Pharmacol Exp Ther
September 1994
270
:
1127
-
1133
Abstract
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S K Teoh
,
Z Sarnyai
,
J H Mendelson
,
N K Mello
,
S A Springer
,
J W Sholar
,
M Wapler
,
J C Kuehnle
,
and
H Gelles
Cocaine effects on pulsatile secretion of ACTH in men.
J Pharmacol Exp Ther
September 1994
270
:
1134
-
1138
Abstract
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K J LePard
and
R L Stephens, Jr
Serotonin inhibits gastric acid secretion through a 5-hydroxytryptamine1-like receptor in the rat.
J Pharmacol Exp Ther
September 1994
270
:
1139
-
1144
Abstract
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T Oguro
,
Z Gregus
,
C Madhu
,
L Liu
,
and
C D Klaassen
Molybdate depletes hepatic 3-phosphoadenosine 5-phosphosulfate and impairs the sulfation of acetaminophen in rats.
J Pharmacol Exp Ther
September 1994
270
:
1145
-
1151
Abstract
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A F Hajj-Ali
,
T M Reilly
,
and
P C Wong
Modulation of renal vasoconstrictor effect of NG-nitro-L-arginine in rabbit by angiotensin II and alpha-1 adrenergic receptor blockade.
J Pharmacol Exp Ther
September 1994
270
:
1152
-
1157
Abstract
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G Yadid
,
K Pacak
,
I J Kopin
,
and
D S Goldstein
Endogenous serotonin stimulates striatal dopamine release in conscious rats.
J Pharmacol Exp Ther
September 1994
270
:
1158
-
1165
Abstract
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L B Fernandes
,
W C Hubbard
,
and
B J Undem
Release of inflammatory mediators from guinea pig trachea by electrical field stimulation: lack of neuronal involvement.
J Pharmacol Exp Ther
September 1994
270
:
1166
-
1170
Abstract
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H C Lee
,
J J Cai
,
and
H Yu
Effect of protein kinase C on cyclic 3',5'-adenosine monophosphate-dependent phosphodiesterase in hypertrophic cardiomyopathic hamster hearts.
J Pharmacol Exp Ther
September 1994
270
:
1171
-
1176
Abstract
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F L Smith
,
D A Brase
,
D S Dombrowski
,
and
W L Dewey
Endogenous opioids released by suspending mice by the tail selectively enhance spinal mu opioid analgesia.
J Pharmacol Exp Ther
September 1994
270
:
1177
-
1185
Abstract
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F P Lacreta
,
J M Brennan
,
S L Nash
,
R L Comis
,
K D Tew
,
and
P J O'Dwyer
Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer.
J Pharmacol Exp Ther
September 1994
270
:
1186
-
1191
Abstract
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K Yin
,
P V Halushka
,
Y T Yan
,
and
P Y Wong
Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets.
J Pharmacol Exp Ther
September 1994
270
:
1192
-
1196
Abstract
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D E Wesson
and
S J Elliott
Xanthine oxidase inhibits transmembrane signal transduction in vascular endothelial cells.
J Pharmacol Exp Ther
September 1994
270
:
1197
-
1207
Abstract
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S C Black
,
C S Schasteen
,
R H Weiss
,
D P Riley
,
E M Driscoll
,
and
B R Lucchesi
Inhibition of in vivo myocardial ischemic and reperfusion injury by a synthetic manganese-based superoxide dismutase mimetic.
J Pharmacol Exp Ther
September 1994
270
:
1208
-
1215
Abstract
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J E Caldwell
,
J Szenohradszky
,
V Segredo
,
P M Wright
,
C McLoughlin
,
M L Sharma
,
L D Gruenke
,
D M Fisher
,
and
R D Miller
The pharmacodynamics and pharmacokinetics of the metabolite 3-desacetylvecuronium (ORG 7268) and its parent compound, vecuronium, in human volunteers.
J Pharmacol Exp Ther
September 1994
270
:
1216
-
1222
Abstract
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T G Kokate
,
B E Svensson
,
and
M A Rogawski
Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation.
J Pharmacol Exp Ther
September 1994
270
:
1223
-
1229
Abstract
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B K Tolliver
,
J K Belknap
,
W E Woods
,
and
J M Carney
Genetic analysis of sensitization and tolerance to cocaine.
J Pharmacol Exp Ther
September 1994
270
:
1230
-
1238
Abstract
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T S Gaginella
,
N Mascolo
,
A A Izzo
,
G Autore
,
and
F Capasso
Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase.
J Pharmacol Exp Ther
September 1994
270
:
1239
-
1245
Abstract
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K M Standifer
,
J Cheng
,
A I Brooks
,
C P Honrado
,
W Su
,
L M Visconti
,
J L Biedler
,
and
G W Pasternak
Biochemical and pharmacological characterization of mu, delta and kappa 3 opioid receptors expressed in BE(2)-C neuroblastoma cells.
J Pharmacol Exp Ther
September 1994
270
:
1246
-
1255
Abstract
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A Nishida
,
Y Takinami
,
H Yuki
,
A Kobayashi
,
S Akuzawa
,
T Kamato
,
H Ito
,
M Yamano
,
Y Nagakura
,
and
K Miyata
YM022 [(R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo-5-phenyl- 1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea], a potent and selective gastrin/cholecystokinin-B receptor antagonist, prevents gastric and duodenal lesions in rats.
J Pharmacol Exp Ther
September 1994
270
:
1256
-
1261
Abstract
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J Auta
,
P Giusti
,
A Guidotti
,
and
E Costa
Imidazenil, a partial positive allosteric modulator of GABAA receptors, exhibits low tolerance and dependence liabilities in the rat.
J Pharmacol Exp Ther
September 1994
270
:
1262
-
1269
Abstract
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M M Foreman
,
R W Fuller
,
K Rasmussen
,
D L Nelson
,
D O Calligaro
,
L Zhang
,
J E Barrett
,
R N Booher
,
C J Paget, Jr
,
and
M E Flaugh
Pharmacological characterization of LY293284: A 5-HT1A receptor agonist with high potency and selectivity.
J Pharmacol Exp Ther
September 1994
270
:
1270
-
1281
Abstract
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M O'Donnell
,
R J Garippa
,
N Rinaldi
,
W M Selig
,
B Simko
,
L Renzetti
,
S A Tannu
,
M A Wasserman
,
A Welton
,
and
D R Bolin
Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part I: In vitro and in vivo bronchodilator studies.
J Pharmacol Exp Ther
September 1994
270
:
1282
-
1288
Abstract
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M O'Donnell
,
R J Garippa
,
N Rinaldi
,
W M Selig
,
J E Tocker
,
S A Tannu
,
M A Wasserman
,
A Welton
,
and
D R Bolin
Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part II: Effect on in vitro and in vivo models of pulmonary anaphylaxis.
J Pharmacol Exp Ther
September 1994
270
:
1289
-
1294
Abstract
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X P Zeng
and
E Burcher
Use of selective antagonists for further characterization of tachykinin NK-2, NK-1 and possible "septide-selective" receptors in guinea pig bronchus.
J Pharmacol Exp Ther
September 1994
270
:
1295
-
1300
Abstract
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A Lothe
,
P Li
,
C Tong
,
Y Yoon
,
H Bouaziz
,
D J Detweiler
,
and
J C Eisenach
Spinal cholinergic alpha-2 adrenergic interactions in analgesia and hemodynamic control: role of muscarinic receptor subtypes and nitric oxide.
J Pharmacol Exp Ther
September 1994
270
:
1301
-
1306
Abstract
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C Y Chen
,
V F Pang
,
and
C S Chen
Assessment of ibuprofen-associated nephrotoxicity in renal dysfunction.
J Pharmacol Exp Ther
September 1994
270
:
1307
-
1312
Abstract
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Y Kondo
,
S M Kuo
,
and
J S Lazo
Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum.
J Pharmacol Exp Ther
September 1994
270
:
1313
-
1318
Abstract
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K Okazaki
,
T Ishikawa
,
M Inui
,
M Tada
,
K Goshima
,
T Okamoto
,
and
H Hidaka
KN-62, a specific Ca++/calmodulin-dependent protein kinase inhibitor, reversibly depresses the rate of beating of cultured fetal mouse cardiac myocytes.
J Pharmacol Exp Ther
September 1994
270
:
1319
-
1324
Abstract
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T L Knight
,
K M Scatchard
,
F N Van Pelt
,
and
J G Kenna
Sera from patients with halothane hepatitis contain antibodies to halothane-induced liver antigens which are not detectable by immunoblotting.
J Pharmacol Exp Ther
September 1994
270
:
1325
-
1333
Abstract
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W Zhu
,
C Newton
,
Y Daaka
,
H Friedman
,
and
T W Klein
delta 9-Tetrahydrocannabinol enhances the secretion of interleukin 1 from endotoxin-stimulated macrophages.
J Pharmacol Exp Ther
September 1994
270
:
1334
-
1339
Abstract
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J L Masferrer
,
S T Reddy
,
B S Zweifel
,
K Seibert
,
P Needleman
,
R S Gilbert
,
and
H R Herschman
In vivo glucocorticoids regulate cyclooxygenase-2 but not cyclooxygenase-1 in peritoneal macrophages.
J Pharmacol Exp Ther
September 1994
270
:
1340
-
1344
Abstract
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C A Fornal
,
W J Litto
,
C W Metzler
,
F Marrosu
,
K Tada
,
and
B L Jacobs
Single-unit responses of serotonergic dorsal raphe neurons to 5-HT1A agonist and antagonist drug administration in behaving cats.
J Pharmacol Exp Ther
September 1994
270
:
1345
-
1358
Abstract
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C A Fornal
,
F Marrosu
,
C W Metzler
,
K Tada
,
and
B L Jacobs
Effects of the putative 5-hydroxytryptamine1A antagonists BMY 7378, NAN 190 and (-)-propranolol on serotonergic dorsal raphe unit activity in behaving cats.
J Pharmacol Exp Ther
September 1994
270
:
1359
-
1366
Abstract
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J C Kraner
,
E T Morgan
,
and
J R Halpert
Selective suppression of rat hepatic cytochrome P450 2C11 by chloramphenicol.
J Pharmacol Exp Ther
September 1994
270
:
1367
-
1372
Abstract
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A B Noach
,
M Sakai
,
M C Blom-Roosemalen
,
H R de Jonge
,
A G de Boer
,
and
D D Breimer
Effect of anisotonic conditions on the transport of hydrophilic model compounds across monolayers of human colonic cell lines.
J Pharmacol Exp Ther
September 1994
270
:
1373
-
1380
Abstract
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K Raynor
,
H Kong
,
J Hines
,
G Kong
,
J Benovic
,
K Yasuda
,
G I Bell
,
and
T Reisine
Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor.
J Pharmacol Exp Ther
September 1994
270
:
1381
-
1386
Abstract
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E M Unterwald
,
A Ho
,
J M Rubenfeld
,
and
M J Kreek
Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration.
J Pharmacol Exp Ther
September 1994
270
:
1387
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1396
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J Pharmacol Exp Ther
September 1994
270
:
1397
Abstract
Full Text (PDF)
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September 1994; 270 (3)
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