Abstract
1. In nine anesthetized dogs after atropine, ephedrine given intravenously increased the submaxillary flow in two cases, slightly in one, but had no effect in the other six animals over a wide range of dosage. In intact dogs, ephedrine intravenously, in large doses close to the M.L.D., always produced salivation.
2. In two dogs with Heidenhain pouches and three with Pavlov fundus pouches, ephedrine given subcutaneously or intravenously increased the gastric secretion although very slightly. The increase was less than that after a meal.
3. Ephedrine had no action on pancreatic secretion, bile flow or intestinal secretion, either in anesthetized or in unanesthetized dogs which had been previously submitted to operative procedures in order to enable one to make the required observations.
Footnotes
- Received August 8, 1925.
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