Table of Contents

May 1994; 269 (2)

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- G M Pieper,
- G A Clarke,
- and G J Gross
Stimulatory and inhibitory action of nitric oxide donor agents vs. nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes.
J Pharmacol Exp Ther May 1994 269:451-456
- Abstract
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- M Ozawa,
- K Sugimachi,
- Y Nakada-Kometani,
- T Akai,
- and M Yamaguchi
Chronic pharmacological activities of the novel anxiolytic beta-carboline abecarnil in rats.
J Pharmacol Exp Ther May 1994 269:457-462
- Abstract
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- Y X Wang and
- C C Pang
Effects of adrenalectomy and chemical sympathectomy on pressor and tachycardic responses to diphenyleneiodonium.
J Pharmacol Exp Ther May 1994 269:463-469
- Abstract
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- E Agneter,
- I S Hoffmann,
- E A Singer,
- and L X Cubeddu
Behavior of mesocortical dopamine terminals during single and repetitive stimulation: comparison with nigrostriatal neurons.
J Pharmacol Exp Ther May 1994 269:470-476
- Abstract
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- R Sheldon,
- E Thakore,
- L Wilson,
- and H Duff
Interaction of drug metabolites with the class I antiarrhythmic drug receptor on rat cardiac myocytes.
J Pharmacol Exp Ther May 1994 269:477-481
- Abstract
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- S Hashimoto,
- Y Kawai,
- and T Ohhashi
Effects of vasoactive substances on the pig isolated hepatic lymph vessels.
J Pharmacol Exp Ther May 1994 269:482-488
- Abstract
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- H Ohnota,
- T Koizumi,
- N Tsutsumi,
- M Kobayashi,
- S Inoue,
- and F Sato
Novel rapid- and short-acting hypoglycemic agent, a calcium(2s)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) that acts on the sulfonylurea receptor: comparison of effects between KAD-1229 and gliclazide.
J Pharmacol Exp Ther May 1994 269:489-495
- Abstract
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- N M Griffiths,
- B H Hirst,
- and N L Simmons
Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?
J Pharmacol Exp Ther May 1994 269:496-502
- Abstract
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- L G Aguayo and
- J Grossie
Dopamine inhibits a sustained calcium current through activation of alpha adrenergic receptors and a GTP-binding protein in adult rat sympathetic neurons.
J Pharmacol Exp Ther May 1994 269:503-508
- Abstract
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- J S Zhang,
- J C Van Meel,
- M Pfaffendorf,
- and P A Van Zwieten
Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; the influence of receptor reserve.
J Pharmacol Exp Ther May 1994 269:509-514
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- C Breugnot,
- S Privat,
- C Guillonneau,
- G Regnier,
- F Bouzom,
- J P Vilaine,
- and A Lenaers
S 12340: a potent inhibitor of the oxidative modification of low-density lipoprotein in vitro and ex vivo in WHHL rabbits.
J Pharmacol Exp Ther May 1994 269:515-520
- Abstract
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- A Hoogerkamp,
- P W Vis,
- M Danhof,
- and R A Voskuyl
Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat.
J Pharmacol Exp Ther May 1994 269:521-528
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- Y Egi,
- Y Matsumura,
- S Murata,
- T Umekawa,
- K Hisaki,
- M Takaoka,
- and S Morimoto
The effects of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs.
J Pharmacol Exp Ther May 1994 269:529-535
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- G J Grover,
- A J D'Alonzo,
- P G Sleph,
- S Dzwonczyk,
- T A Hess,
- and R B Darbenzio
The cardioprotective and electrophysiological effects of cromakalim are attenuated by meclofenamate through a cyclooxygenase-independent mechanism.
J Pharmacol Exp Ther May 1994 269:536-540
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- J J Lynch, Jr,
- A A Wallace,
- R F Stupienski, 3rd,
- E P Baskin,
- C M Beare,
- S D Appleby,
- J J Salata,
- N K Jurkiewicz,
- M C Sanguinetti,
- and R B Stein
Cardiac electrophysiologic and antiarrhythmic actions of two long-acting spirobenzopyran piperidine class III agents, L-702,958 and L-706,000 [MK-499].
J Pharmacol Exp Ther May 1994 269:541-554
- Abstract
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- C S Konkoy,
- S M Waters,
- and T P Davis
Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat brain slices.
J Pharmacol Exp Ther May 1994 269:555-563
- Abstract
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- F Menzaghi,
- R L Howard,
- S C Heinrichs,
- W Vale,
- J Rivier,
- and G F Koob
Characterization of a novel and potent corticotropin-releasing factor antagonist in rats.
J Pharmacol Exp Ther May 1994 269:564-572
- Abstract
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- A J Carter
Many agents that antagonize the NMDA receptor-channel complex in vivo also cause disturbances of motor coordination.
J Pharmacol Exp Ther May 1994 269:573-580
- Abstract
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- B I Ghanayem,
- I M Sanchez,
- and L T Burka
Investigation of methacrylonitrile metabolism and the metabolic basis for the differences in its toxicity in rats and mice.
J Pharmacol Exp Ther May 1994 269:581-588
- Abstract
- Full Text (PDF)
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- M Ito,
- A Naruse,
- I Yamamoto,
- M Oguri,
- Y Suzuki,
- N Satake,
- and S Shibata
Nephrosis augments contractile response to adrenoceptor agonists by the decrease in release of endothelium-derived relaxing factor from the endothelial cells.
J Pharmacol Exp Ther May 1994 269:589-595
- Abstract
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- B L Hodges,
- M J Gagnon,
- T R Gillespie,
- J R Breneisen,
- D F O'Leary,
- S Hara,
- and R M Quock
Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockade.
J Pharmacol Exp Ther May 1994 269:596-600
- Abstract
- Full Text (PDF)
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- C E McDonald,
- M J Gagnon,
- E A Ellenberger,
- B L Hodges,
- J K Ream,
- S A Tousman,
- and R M Quock
Inhibitors of nitric oxide synthesis antagonize nitrous oxide antinociception in mice and rats.
J Pharmacol Exp Ther May 1994 269:601-608
- Abstract
- Full Text (PDF)
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- T C Krejcie,
- T K Henthorn,
- C A Shanks,
- and M J Avram
A recirculatory pharmacokinetic model describing the circulatory mixing, tissue distribution and elimination of antipyrine in dogs.
J Pharmacol Exp Ther May 1994 269:609-616
- Abstract
- Full Text (PDF)
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- S W Watts and
- R C Webb
Mechanism of ergonovine-induced contraction in the mesenteric artery from deoxycorticosterone acetate-salt hypertensive rat.
J Pharmacol Exp Ther May 1994 269:617-625
- Abstract
- Full Text (PDF)
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- R K Rao,
- P J Riviere,
- X Pascaud,
- J L Junien,
- and F Porreca
Tonic regulation of mouse ileal ion transport by nitric oxide.
J Pharmacol Exp Ther May 1994 269:626-631
- Abstract
- Full Text (PDF)
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- S M Sadrzadeh,
- A A Nanji,
- and P L Price
The oral iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats.
J Pharmacol Exp Ther May 1994 269:632-636
- Abstract
- Full Text (PDF)
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- T M Cabrera and
- G Battaglia
Delayed decreases in brain 5-hydroxytryptamine2A/2C receptor density and function in male rat progeny following prenatal fluoxetine.
J Pharmacol Exp Ther May 1994 269:637-645
- Abstract
- Full Text (PDF)
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- M Tencé,
- J Cordier,
- J Premont,
- and J Glowinski
Muscarinic cholinergic agonists stimulate arachidonic acid release from mouse striatal neurons in primary culture.
J Pharmacol Exp Ther May 1994 269:646-653
- Abstract
- Full Text (PDF)
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- P Wils,
- A Warnery,
- V Phung-Ba,
- S Legrain,
- and D Scherman
High lipophilicity decreases drug transport across intestinal epithelial cells.
J Pharmacol Exp Ther May 1994 269:654-658
- Abstract
- Full Text (PDF)
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- H Hohage,
- M Löhr,
- U Querl,
- and J Greven
The renal basolateral transport system for organic anions: properties of the regulation mechanism.
J Pharmacol Exp Ther May 1994 269:659-664
- Abstract
- Full Text (PDF)
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- T Maurice,
- M Hiramatsu,
- T Kameyama,
- T Hasegawa,
- and T Nabeshima
Cholecystokinin-related peptides, after systemic or central administration, prevent carbon monoxide-induced amnesia in mice.
J Pharmacol Exp Ther May 1994 269:665-673
- Abstract
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- C A Branch and
- M M Knuepfer
Causes of differential cardiovascular sensitivity to cocaine. I: Studies in conscious rats.
J Pharmacol Exp Ther May 1994 269:674-683
- Abstract
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- K J Ullrich,
- G Fritzsch,
- G Rumrich,
- and C David
Polysubstrates: substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: sulfamoyl-, sulfonylurea-, thiazide- and benzeneamino-carboxylate (nicotinate) compounds.
J Pharmacol Exp Ther May 1994 269:684-692
- Abstract
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- D J Carr,
- L R Gerak,
- and C P France
Naltrexone antagonizes the analgesic and immunosuppressive effects of morphine in mice.
J Pharmacol Exp Ther May 1994 269:693-698
- Abstract
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- E T Iwamoto and
- L Marion
Pharmacological evidence that nitric oxide mediates the antinociception produced by muscarinic agonists in the rostral ventral medulla of rats.
J Pharmacol Exp Ther May 1994 269:699-708
- Abstract
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- Q M Chen,
- D D Smyth,
- J K McKenzie,
- G B Glavin,
- J G Gu,
- J D Geiger,
- and F S LaBella
Chlorotyrosine exerts renal effects and antagonizes renal and gastric responses to atrial natriuretic peptide.
J Pharmacol Exp Ther May 1994 269:709-716
- Abstract
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- J T Emmick,
- S Kwon,
- K R Bidasee,
- K T Besch,
- and H R Besch, Jr
Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes.
J Pharmacol Exp Ther May 1994 269:717-724
- Abstract
- Full Text (PDF)
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- A Nishida,
- K Miyata,
- R Tsutsumi,
- H Yuki,
- S Akuzawa,
- A Kobayashi,
- T Kamato,
- H Ito,
- M Yamano,
- and Y Katuyama
Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.
J Pharmacol Exp Ther May 1994 269:725-731
- Abstract
- Full Text (PDF)
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- H T Yang and
- M Endoh
Dissociation of the positive inotropic effect of methoxamine from the hydrolysis of phosphoinositide in rabbit ventricular myocardium: a comparison with the effects of phenylephrine and the subtype of the alpha-1 adrenoceptor involved.
J Pharmacol Exp Ther May 1994 269:732-742
- Abstract
- Full Text (PDF)
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- G R King,
- E H Ellinwood, Jr,
- C Silvia,
- C M Joyner,
- Z Xue,
- M G Caron,
- and T H Lee
Withdrawal from continuous or intermittent cocaine administration: changes in D2 receptor function.
J Pharmacol Exp Ther May 1994 269:743-749
- Abstract
- Full Text (PDF)
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- C L Williams,
- G C Rosenfeld,
- N Dafny,
- S N Fang,
- V J Hruby,
- G Bowden,
- C A Cullinan,
- and T F Burks
SNF9007: a novel analgesic that acts simultaneously at delta 1, delta 2 and mu opioid receptors.
J Pharmacol Exp Ther May 1994 269:750-755
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- L O Derewlany,
- B Knie,
- and G Koren
Arylamine N-acetyltransferase activity of the human placenta.
J Pharmacol Exp Ther May 1994 269:756-760
- Abstract
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- L O Derewlany,
- B Knie,
- and G Koren
Human placental transfer and metabolism of p-aminobenzoic acid.
J Pharmacol Exp Ther May 1994 269:761-765
- Abstract
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- G Alloatti,
- G Montrucchio,
- and G Camussi
Role of platelet-activating factor (PAF) in oxygen radical-induced cardiac dysfunction.
J Pharmacol Exp Ther May 1994 269:766-771
- Abstract
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- P Savi,
- M C Laplace,
- J P Maffrand,
- and J M Herbert
Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine.
J Pharmacol Exp Ther May 1994 269:772-777
- Abstract
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- R H Schwinger,
- M Böhm,
- A Koch,
- I Morano,
- J C Rüegg,
- and E Erdmann
Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium.
J Pharmacol Exp Ther May 1994 269:778-786
- Abstract
- Full Text (PDF)
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- C Perret,
- M T Foultier,
- V Vonarx-Coinsman,
- O Quancard,
- A Combre,
- and T Patrice
Malondialdehyde dosimetry in laser-irradiated tissues sensitized by hematoporphyrin derivative.
J Pharmacol Exp Ther May 1994 269:787-791
- Abstract
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- U McCann,
- G Hatzidimitriou,
- A Ridenour,
- C Fischer,
- J Yuan,
- J Katz,
- and G Ricaurte
Dexfenfluramine and serotonin neurotoxicity: further preclinical evidence that clinical caution is indicated.
J Pharmacol Exp Ther May 1994 269:792-798
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- H Hara,
- K Tanaka,
- Y Harada,
- and T Sukamoto
Sigma receptor-mediated effects of a new antiulcer agent, KB-5492, on experimental gastric mucosal lesions and gastric alkaline secretion in rats.
J Pharmacol Exp Ther May 1994 269:799-805
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- K M Merchant,
- G R Hanson,
- and D M Dorsa
Induction of neurotensin and c-fos mRNA in distinct subregions of rat neostriatum after acute methamphetamine: comparison with acute haloperidol effects.
J Pharmacol Exp Ther May 1994 269:806-812
- Abstract
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- J H Hochman,
- J A Fix,
- and E L LeCluyse
In vitro and in vivo analysis of the mechanism of absorption enhancement by palmitoylcarnitine.
J Pharmacol Exp Ther May 1994 269:813-822
- Abstract
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- M Ohtsuyama,
- F Sato,
- T Toyomoto,
- and K Sato
Stimulation of Cl conductance by minoxidil sulfate and K conductance by minoxidil in eccrine clear cells.
J Pharmacol Exp Ther May 1994 269:823-831
- Abstract
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- A A Nanji,
- S Zhao,
- S Khwaja,
- S M Sadrzadeh,
- and D J Waxman
Cimetidine prevents alcoholic hepatic injury in the intragastric feeding rat model.
J Pharmacol Exp Ther May 1994 269:832-837
- Abstract
- Full Text (PDF)
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- C A Louis,
- S G Wood,
- V Kostrubsky,
- P R Sinclair,
- and J F Sinclair
Synergistic increases in rat hepatic cytochrome P450s by ethanol and isopentanol.
J Pharmacol Exp Ther May 1994 269:838-845
- Abstract
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- D Van Rossum,
- D P Ménard,
- A Fournier,
- S St-Pierre,
- and R Quirion
Binding profile of a selective calcitonin gene-related peptide (CGRP) receptor antagonist ligand, [125I-Tyr]hCGRP8-37, in rat brain and peripheral tissues.
J Pharmacol Exp Ther May 1994 269:846-853
- Abstract
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- S H Graham,
- J Chen,
- J Lan,
- M J Leach,
- and R P Simon
Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion.
J Pharmacol Exp Ther May 1994 269:854-859
- Abstract
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- T Umekawa,
- Y Matsumura,
- N Yoshimura,
- S Murata,
- K Takada,
- Y Tsukahara,
- M Takaoka,
- and S Morimoto
Platelets-induced stimulation of endothelin-1 production and inhibition by phosphoramidon.
J Pharmacol Exp Ther May 1994 269:860-866
- Abstract
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- C G Plopper,
- A J Weir,
- S J Nishio,
- A Chang,
- M Voit,
- R M Philpot,
- and A R Buckpitt
Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits.
J Pharmacol Exp Ther May 1994 269:867-880
- Abstract
- Full Text (PDF)
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- M Cho,
- C Chichester,
- D Morin,
- C Plopper,
- and A Buckpitt
Covalent interactions of reactive naphthalene metabolites with proteins.
J Pharmacol Exp Ther May 1994 269:881-889
- Abstract
- Full Text (PDF)

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J Pharmacol Exp Ther May 1994 269:889
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November 2009, 331 (2)

Stimulatory and inhibitory action of nitric oxide donor agents vs. nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes.

Chronic pharmacological activities of the novel anxiolytic beta-carboline abecarnil in rats.

Effects of adrenalectomy and chemical sympathectomy on pressor and tachycardic responses to diphenyleneiodonium.

Behavior of mesocortical dopamine terminals during single and repetitive stimulation: comparison with nigrostriatal neurons.

Interaction of drug metabolites with the class I antiarrhythmic drug receptor on rat cardiac myocytes.

Effects of vasoactive substances on the pig isolated hepatic lymph vessels.

Novel rapid- and short-acting hypoglycemic agent, a calcium(2s)-2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl) propionate (KAD-1229) that acts on the sulfonylurea receptor: comparison of effects between KAD-1229 and gliclazide.

Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?

Dopamine inhibits a sustained calcium current through activation of alpha adrenergic receptors and a GTP-binding protein in adult rat sympathetic neurons.

Different types of angiotensin II receptor antagonism induced by BIBS 222 in the rat portal vein and rabbit aorta; the influence of receptor reserve.

S 12340: a potent inhibitor of the oxidative modification of low-density lipoprotein in vitro and ex vivo in WHHL rabbits.

Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat.

The effects of NG-nitro-L-arginine, a nitric oxide synthase inhibitor, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs.

The cardioprotective and electrophysiological effects of cromakalim are attenuated by meclofenamate through a cyclooxygenase-independent mechanism.

Cardiac electrophysiologic and antiarrhythmic actions of two long-acting spirobenzopyran piperidine class III agents, L-702,958 and L-706,000 [MK-499].

Acute administration of neuroleptics decreases neurotensin metabolism on intact, regional rat brain slices.

Characterization of a novel and potent corticotropin-releasing factor antagonist in rats.

Many agents that antagonize the NMDA receptor-channel complex in vivo also cause disturbances of motor coordination.

Investigation of methacrylonitrile metabolism and the metabolic basis for the differences in its toxicity in rats and mice.

Nephrosis augments contractile response to adrenoceptor agonists by the decrease in release of endothelium-derived relaxing factor from the endothelial cells.

Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockade.

Inhibitors of nitric oxide synthesis antagonize nitrous oxide antinociception in mice and rats.

A recirculatory pharmacokinetic model describing the circulatory mixing, tissue distribution and elimination of antipyrine in dogs.

Mechanism of ergonovine-induced contraction in the mesenteric artery from deoxycorticosterone acetate-salt hypertensive rat.

Tonic regulation of mouse ileal ion transport by nitric oxide.

The oral iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats.

Delayed decreases in brain 5-hydroxytryptamine2A/2C receptor density and function in male rat progeny following prenatal fluoxetine.

Muscarinic cholinergic agonists stimulate arachidonic acid release from mouse striatal neurons in primary culture.

High lipophilicity decreases drug transport across intestinal epithelial cells.

The renal basolateral transport system for organic anions: properties of the regulation mechanism.

Cholecystokinin-related peptides, after systemic or central administration, prevent carbon monoxide-induced amnesia in mice.

Causes of differential cardiovascular sensitivity to cocaine. I: Studies in conscious rats.

Polysubstrates: substances that interact with renal contraluminal PAH, sulfate, and NMeN transport: sulfamoyl-, sulfonylurea-, thiazide- and benzeneamino-carboxylate (nicotinate) compounds.

Naltrexone antagonizes the analgesic and immunosuppressive effects of morphine in mice.

Pharmacological evidence that nitric oxide mediates the antinociception produced by muscarinic agonists in the rostral ventral medulla of rats.

Chlorotyrosine exerts renal effects and antagonizes renal and gastric responses to atrial natriuretic peptide.

Dual effect of suramin on calcium fluxes across sarcoplasmic reticulum vesicle membranes.

Pharmacological profile of (R)-1-[2,3-dihydro-1-(2'-methylphenacyl)-2-oxo- 5-phenyl-1H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea (YM022), a new potent and selective gastrin/cholecystokinin-B receptor antagonist, in vitro and in vivo.

Dissociation of the positive inotropic effect of methoxamine from the hydrolysis of phosphoinositide in rabbit ventricular myocardium: a comparison with the effects of phenylephrine and the subtype of the alpha-1 adrenoceptor involved.

Withdrawal from continuous or intermittent cocaine administration: changes in D2 receptor function.

SNF9007: a novel analgesic that acts simultaneously at delta 1, delta 2 and mu opioid receptors.

Arylamine N-acetyltransferase activity of the human placenta.

Human placental transfer and metabolism of p-aminobenzoic acid.

Role of platelet-activating factor (PAF) in oxygen radical-induced cardiac dysfunction.

Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine.

Inotropic effect of the cardioprotective agent 2,3-butanedione monoxime in failing and nonfailing human myocardium.

Malondialdehyde dosimetry in laser-irradiated tissues sensitized by hematoporphyrin derivative.

Dexfenfluramine and serotonin neurotoxicity: further preclinical evidence that clinical caution is indicated.

Sigma receptor-mediated effects of a new antiulcer agent, KB-5492, on experimental gastric mucosal lesions and gastric alkaline secretion in rats.

Induction of neurotensin and c-fos mRNA in distinct subregions of rat neostriatum after acute methamphetamine: comparison with acute haloperidol effects.

In vitro and in vivo analysis of the mechanism of absorption enhancement by palmitoylcarnitine.

Stimulation of Cl conductance by minoxidil sulfate and K conductance by minoxidil in eccrine clear cells.

Cimetidine prevents alcoholic hepatic injury in the intragastric feeding rat model.

Synergistic increases in rat hepatic cytochrome P450s by ethanol and isopentanol.

Binding profile of a selective calcitonin gene-related peptide (CGRP) receptor antagonist ligand, [125I-Tyr]hCGRP8-37, in rat brain and peripheral tissues.

Neuroprotective effects of a use-dependent blocker of voltage-dependent sodium channels, BW619C89, in rat middle cerebral artery occlusion.

Platelets-induced stimulation of endothelin-1 production and inhibition by phosphoramidon.

Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits.

Covalent interactions of reactive naphthalene metabolites with proteins.

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