Table of Contents

April 1994; 269 (1)

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- J Imagawa,
- K Kamei,
- S Yoshida,
- I Sugo,
- T Koga,
- and H Nabata
In vivo bronchodilator action of a novel K+ channel opener, KC 399, in the guinea pig.
J Pharmacol Exp Ther April 1994 269:1-6
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- F Betoin,
- D Ardid,
- A Herbet,
- O Aumaitre,
- J L Kemeny,
- P Duchene-Marullaz,
- J Lavarenne,
- and A Eschalier
Evidence for a central long-lasting antinociceptive effect of vapreotide, an analog of somatostatin, involving an opioidergic mechanism.
J Pharmacol Exp Ther April 1994 269:7-14
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- J Itoh,
- M Ukai,
- and T Kameyama
Dynorphin A-(1-13) potently improves the impairment of spontaneous alternation performance induced by the mu-selective opioid receptor agonist DAMGO in mice.
J Pharmacol Exp Ther April 1994 269:15-21
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- T Colombo,
- M Zucchetti,
- and M D'Incalci
Cyclosporin A markedly changes the distribution of doxorubicin in mice and rats.
J Pharmacol Exp Ther April 1994 269:22-27
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- M M Barzago,
- D Omarini,
- A Bortolotti,
- F F Stellari,
- G Lucchini,
- S Efrati,
- and M Bonati
Mefloquine transfer during in vitro human placenta perfusion.
J Pharmacol Exp Ther April 1994 269:28-31
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- M Serra,
- C A Ghiani,
- C Motzo,
- T Cuccheddu,
- S Floris,
- P Giusti,
- and G Biggio
Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.
J Pharmacol Exp Ther April 1994 269:32-38
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- J C Wurzer,
- R J Tallarida,
- and M A Sirover
New mechanism of action of the cancer chemotherapeutic agent 5-fluorouracil in human cells.
J Pharmacol Exp Ther April 1994 269:39-43
- Abstract
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- I Terleckyj and
- P K Sonsalla
The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine-induced dopaminergic neurotoxicity via interactions at dopamine receptors.
J Pharmacol Exp Ther April 1994 269:44-50
- Abstract
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- A Sanbe,
- K Tanonaka,
- Y Niwano,
- and S Takeo
Improvement of cardiac function and myocardial energy metabolism of rats with chronic heart failure by long-term coenzyme Q10 treatment.
J Pharmacol Exp Ther April 1994 269:51-56
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- G Zernig,
- E R Butelman,
- J W Lewis,
- E A Walker,
- and J H Woods
In vivo determination of mu opioid receptor turnover in rhesus monkeys after irreversible blockade with clocinnamox.
J Pharmacol Exp Ther April 1994 269:57-65
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- M T Slawsky and
- N A Castle
K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes.
J Pharmacol Exp Ther April 1994 269:66-74
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- M J Mangino,
- M K Murphy,
- and C B Anderson
Effects of the arachidonate 5-lipoxygenase synthesis inhibitor A-64077 in intestinal ischemia-reperfusion injury.
J Pharmacol Exp Ther April 1994 269:75-81
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- C K Kost, Jr,
- W A Herzer,
- P Li,
- and E K Jackson
Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats.
J Pharmacol Exp Ther April 1994 269:82-88
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- P A Cossum,
- L Truong,
- S R Owens,
- P M Markham,
- J P Shea,
- and S T Crooke
Pharmacokinetics of a 14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats.
J Pharmacol Exp Ther April 1994 269:89-94
- Abstract
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- I A Paul,
- G Nowak,
- R T Layer,
- P Popik,
- and P Skolnick
Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments.
J Pharmacol Exp Ther April 1994 269:95-102
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- W Piekoszewski,
- F S Chow,
- and W J Jusko
Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits.
J Pharmacol Exp Ther April 1994 269:103-109
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- K Bervoets and
- M J Millan
5-HT1A receptors and the tail-flick response. V. Opposite modulation of 5-HT1A receptor-induced spontaneous tail-flicks by alpha 1A- as compared with alpha 2D-adrenoceptors in rat lumbar spinal cord.
J Pharmacol Exp Ther April 1994 269:110-120
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- M J Millan,
- J M Rivet,
- A Gobert,
- H Canton,
- S Veiga,
- and K Bervoets
5-HT1A receptors and the tail-flick response. VI. Intrinsic alpha 1A-adrenoceptor antagonist properties can mask the actions of 5-HT1A receptor agonists in the spontaneous tail-flick paradigm.
J Pharmacol Exp Ther April 1994 269:121-131
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- R W Fuller,
- S K Hemrick-Luecke,
- and H D Snoddy
Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice.
J Pharmacol Exp Ther April 1994 269:132-136
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- T A Kosten,
- M J Miserendino,
- S Chi,
- and E J Nestler
Fischer and Lewis rat strains show differential cocaine effects in conditioned place preference and behavioral sensitization but not in locomotor activity or conditioned taste aversion.
J Pharmacol Exp Ther April 1994 269:137-144
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- P A Bombardt,
- J E Brewer,
- and M G Johnson
Protein binding of tirilazad (U-74006) in human, Sprague-Dawley rat, beagle dog and cynomolgus monkey serum.
J Pharmacol Exp Ther April 1994 269:145-150
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- W E Perkins,
- R G Bianchi,
- S J Tremont,
- P W Collins,
- J J Casler,
- R L Fenton,
- G M Wagner,
- M P McGrath,
- J C Stolzenbach,
- and D L Kowalski
Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem.
J Pharmacol Exp Ther April 1994 269:151-156
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- W Marszalec,
- Y Kurata,
- B J Hamilton,
- D B Carter,
- and T Narahashi
Selective effects of alcohols on gamma-aminobutyric acid A receptor subunits expressed in human embryonic kidney cells.
J Pharmacol Exp Ther April 1994 269:157-163
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- K Nagata and
- T Narahashi
Dual action of the cyclodiene insecticide dieldrin on the gamma-aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons.
J Pharmacol Exp Ther April 1994 269:164-171
- Abstract
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- M Babich,
- G E Alford,
- and R A Nissenson
A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells.
J Pharmacol Exp Ther April 1994 269:172-177
- Abstract
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- S K Mishra and
- K Hermsmeyer
Resting state block and use independence of rat vascular muscle Ca++ channels by Ro 40-5967.
J Pharmacol Exp Ther April 1994 269:178-183
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- J C Crabbe,
- J K Belknap,
- S R Mitchell,
- and L I Crawshaw
Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.
J Pharmacol Exp Ther April 1994 269:184-192
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- S Palea,
- M Corsi,
- C Pietra,
- W Artibani,
- A Calpista,
- G Gaviraghi,
- and D G Trist
ADP beta S induces contraction of the human isolated urinary bladder through a purinoceptor subtype different from P2X and P2Y.
J Pharmacol Exp Ther April 1994 269:193-197
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- C C Chao,
- G Gekker,
- W S Sheng,
- S Hu,
- M Tsang,
- and P K Peterson
Priming effect of morphine on the production of tumor necrosis factor-alpha by microglia: implications in respiratory burst activity and human immunodeficiency virus-1 expression.
J Pharmacol Exp Ther April 1994 269:198-203
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- R J Ott,
- J K Chan,
- V K Ramanathan,
- A C Hui,
- and K M Giacomini
Effect of phenylisothiocyanate on organic cation transport in opossum kidney cells.
J Pharmacol Exp Ther April 1994 269:204-208
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- J Ren,
- E Karpinski,
- and C G Benishin
Inhibition of a K+ current by beta-dendrotoxin in primary and subcultured vascular smooth muscle cells.
J Pharmacol Exp Ther April 1994 269:209-214
- Abstract
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- A L Chamienia and
- E J Johns
Renal functional responses to the 5-HT1A receptor agonist flesinoxan: effects of controlled renal perfusion pressure.
J Pharmacol Exp Ther April 1994 269:215-220
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- M Endou,
- E Poli,
- and R Levi
Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels.
J Pharmacol Exp Ther April 1994 269:221-229
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- M L Adams,
- E R Meyer,
- B N Sewing,
- and T J Cicero
Effects of nitric oxide-related agents on rat testicular function.
J Pharmacol Exp Ther April 1994 269:230-237
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- P Salvati,
- L Dho,
- G Ukmar,
- L Vaga,
- O Rimoldi,
- and C Patrono
A comparative evaluation of thromboxane receptor blockade, thromboxane synthase inhibition and both in animal models of arterial thrombosis.
J Pharmacol Exp Ther April 1994 269:238-245
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- C D Unsworth and
- P B Molinoff
Characterization of a 5-hydroxytryptamine receptor in mouse neuroblastoma N18TG2 cells.
J Pharmacol Exp Ther April 1994 269:246-255
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- L L Simpson,
- J A Coffield,
- and N Bakry
Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins.
J Pharmacol Exp Ther April 1994 269:256-262
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- A A Seymour,
- J H Sheldon,
- P L Smith,
- M Asaad,
- and W L Rogers
Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.
J Pharmacol Exp Ther April 1994 269:263-270
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- H E Shannon,
- F P Bymaster,
- D O Calligaro,
- B Greenwood,
- C H Mitch,
- B D Sawyer,
- J S Ward,
- D T Wong,
- P H Olesen,
- and M J Sheardown
Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors.
J Pharmacol Exp Ther April 1994 269:271-281
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- F P Bymaster,
- D T Wong,
- C H Mitch,
- J S Ward,
- D O Calligaro,
- D D Schoepp,
- H E Shannon,
- M J Sheardown,
- P H Olesen,
- and P D Suzdak
Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232).
J Pharmacol Exp Ther April 1994 269:282-289
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- C S Moravec,
- T Ruhe,
- J R Cifani,
- M Milovanovic,
- and P A Khairallah
Structural and functional consequences of minoxidil-induced cardiac hypertrophy.
J Pharmacol Exp Ther April 1994 269:290-296
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- M D Levitt and
- D G Levitt
The critical role of the rate of ethanol absorption in the interpretation of studies purporting to demonstrate gastric metabolism of ethanol.
J Pharmacol Exp Ther April 1994 269:297-304
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- R H Alper and
- M H Zink, 3rd
Adrenergic and nonadrenergic regulation of hindlimb blood flow during stress in rats.
J Pharmacol Exp Ther April 1994 269:305-312
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- J Zhang,
- L A Chiodo,
- and A S Freeman
Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra.
J Pharmacol Exp Ther April 1994 269:313-321
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- S K Salzman,
- G Kelly,
- J Chavin,
- L Wang,
- M A Puniak,
- C A Agresta,
- and S Azim
Characterization of mianserin neuroprotection in experimental spinal trauma: dose/route response and late treatment.
J Pharmacol Exp Ther April 1994 269:322-328
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- R A Huff,
- J J Corcoran,
- J K Anderson,
- and M B Abou-Donia
Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum.
J Pharmacol Exp Ther April 1994 269:329-335
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- A Zaza,
- G Malfatto,
- and P J Schwartz
Diverse electrophysiologic effects of propafenone and flecainide in canine Purkinje fibers: implications for antiarrhythmic drug classification.
J Pharmacol Exp Ther April 1994 269:336-343
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- Y S Kang and
- W M Pardridge
Use of neutral avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate.
J Pharmacol Exp Ther April 1994 269:344-350
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- L Cooke and
- K H Muntz
Differences in beta adrenergic receptor agonist affinity between cardiac myocytes and coronary arterioles in canine heart.
J Pharmacol Exp Ther April 1994 269:351-357
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- J B Long,
- D D Rigamonti,
- M A Oleshansky,
- C P Wingfield,
- and A Martinez-Arizala
Dynorphin A-induced rat spinal cord injury: evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury.
J Pharmacol Exp Ther April 1994 269:358-366
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- G M Adamson and
- R E Billings
Tumor necrosis factor: receptor binding and expression of receptors in cultured mouse hepatocytes.
J Pharmacol Exp Ther April 1994 269:367-373
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- L H Lash,
- P J Sausen,
- R J Duescher,
- A J Cooley,
- and A A Elfarra
Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
J Pharmacol Exp Ther April 1994 269:374-383
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- R Curi-Pedrosa,
- M Daujat,
- L Pichard,
- J C Ourlin,
- P Clair,
- L Gervot,
- P Lesca,
- J Domergue,
- H Joyeux,
- and G Fourtanier
Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture.
J Pharmacol Exp Ther April 1994 269:384-392
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- M Weller,
- A M Marini,
- B Martin,
- and S M Paul
The reduced unsubstituted pteroate moiety is required for folate toxicity of cultured cerebellar granule neurons.
J Pharmacol Exp Ther April 1994 269:393-401
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- R K Dubey
Vasodilator-derived nitric oxide inhibits fetal calf serum- and angiotensin-II-induced growth of renal arteriolar smooth muscle cells.
J Pharmacol Exp Ther April 1994 269:402-408
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- G E Billman
The effect of adrenergic receptor antagonists on cocaine-induced ventricular fibrillation: alpha but not beta adrenergic receptor antagonists prevent malignant arrhythmias independent of heart rate.
J Pharmacol Exp Ther April 1994 269:409-416
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- C J Omiecinski,
- L Aicher,
- and L Swenson
Developmental expression of human microsomal epoxide hydrolase.
J Pharmacol Exp Ther April 1994 269:417-423
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- A Giacometti,
- D Micheli,
- G Gaviraghi,
- and D G Trist
Quantification of the calcium antagonism of lacidipine by kinetic analysis.
J Pharmacol Exp Ther April 1994 269:424-429
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- L Tesoriere,
- M Ciaccio,
- M Valenza,
- A Bongiorno,
- E Maresi,
- R Albiero,
- and M A Livrea
Effect of vitamin A administration on resistance of rat heart against doxorubicin-induced cardiotoxicity and lethality.
J Pharmacol Exp Ther April 1994 269:430-436
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- M A Klitenick and
- P W Kalivas
Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus.
J Pharmacol Exp Ther April 1994 269:437-448
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J Pharmacol Exp Ther April 1994 269:449
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November 2009, 331 (2)

In vivo bronchodilator action of a novel K+ channel opener, KC 399, in the guinea pig.

Evidence for a central long-lasting antinociceptive effect of vapreotide, an analog of somatostatin, involving an opioidergic mechanism.

Dynorphin A-(1-13) potently improves the impairment of spontaneous alternation performance induced by the mu-selective opioid receptor agonist DAMGO in mice.

Cyclosporin A markedly changes the distribution of doxorubicin in mice and rats.

Mefloquine transfer during in vitro human placenta perfusion.

Imidazenil, a new partial agonist of benzodiazepine receptors, reverses the inhibitory action of isoniazid and stress on gamma-aminobutyric acidA receptor function.

New mechanism of action of the cancer chemotherapeutic agent 5-fluorouracil in human cells.

The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine-induced dopaminergic neurotoxicity via interactions at dopamine receptors.

Improvement of cardiac function and myocardial energy metabolism of rats with chronic heart failure by long-term coenzyme Q10 treatment.

In vivo determination of mu opioid receptor turnover in rhesus monkeys after irreversible blockade with clocinnamox.

K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes.

Effects of the arachidonate 5-lipoxygenase synthesis inhibitor A-64077 in intestinal ischemia-reperfusion injury.

Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats.

Pharmacokinetics of a 14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats.

Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments.

Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits.

5-HT1A receptors and the tail-flick response. V. Opposite modulation of 5-HT1A receptor-induced spontaneous tail-flicks by alpha 1A- as compared with alpha 2D-adrenoceptors in rat lumbar spinal cord.

5-HT1A receptors and the tail-flick response. VI. Intrinsic alpha 1A-adrenoceptor antagonist properties can mask the actions of 5-HT1A receptor agonists in the spontaneous tail-flick paradigm.

Effects of duloxetine, an antidepressant drug candidate, on concentrations of monoamines and their metabolites in rats and mice.

Fischer and Lewis rat strains show differential cocaine effects in conditioned place preference and behavioral sensitization but not in locomotor activity or conditioned taste aversion.

Protein binding of tirilazad (U-74006) in human, Sprague-Dawley rat, beagle dog and cynomolgus monkey serum.

Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem.

Selective effects of alcohols on gamma-aminobutyric acid A receptor subunits expressed in human embryonic kidney cells.

Dual action of the cyclodiene insecticide dieldrin on the gamma-aminobutyric acid receptor-chloride channel complex of rat dorsal root ganglion neurons.

A novel phospholipase C inhibitor and phorbol esters reveal selective regulation of thrombin- and parathyroid hormone-stimulated signaling pathways in rat osteosarcoma cells.

Resting state block and use independence of rat vascular muscle Ca++ channels by Ro 40-5967.

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

ADP beta S induces contraction of the human isolated urinary bladder through a purinoceptor subtype different from P2X and P2Y.

Priming effect of morphine on the production of tumor necrosis factor-alpha by microglia: implications in respiratory burst activity and human immunodeficiency virus-1 expression.

Effect of phenylisothiocyanate on organic cation transport in opossum kidney cells.

Inhibition of a K+ current by beta-dendrotoxin in primary and subcultured vascular smooth muscle cells.

Renal functional responses to the 5-HT1A receptor agonist flesinoxan: effects of controlled renal perfusion pressure.

Histamine H3-receptor signaling in the heart: possible involvement of Gi/Go proteins and N-type Ca++ channels.

Effects of nitric oxide-related agents on rat testicular function.

A comparative evaluation of thromboxane receptor blockade, thromboxane synthase inhibition and both in animal models of arterial thrombosis.

Characterization of a 5-hydroxytryptamine receptor in mouse neuroblastoma N18TG2 cells.

Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins.

Potentiation of the renal responses to bradykinin by inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in anesthetized dogs.

Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors.

Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232).

Structural and functional consequences of minoxidil-induced cardiac hypertrophy.

The critical role of the rate of ethanol absorption in the interpretation of studies purporting to demonstrate gastric metabolism of ethanol.

Adrenergic and nonadrenergic regulation of hindlimb blood flow during stress in rats.

Influence of excitatory amino acid receptor subtypes on the electrophysiological activity of dopaminergic and nondopaminergic neurons in rat substantia nigra.

Characterization of mianserin neuroprotection in experimental spinal trauma: dose/route response and late treatment.

Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum.

Diverse electrophysiologic effects of propafenone and flecainide in canine Purkinje fibers: implications for antiarrhythmic drug classification.

Use of neutral avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate.

Differences in beta adrenergic receptor agonist affinity between cardiac myocytes and coronary arterioles in canine heart.

Dynorphin A-induced rat spinal cord injury: evidence for excitatory amino acid involvement in a pharmacological model of ischemic spinal cord injury.

Tumor necrosis factor: receptor binding and expression of receptors in cultured mouse hepatocytes.

Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.

Omeprazole and lansoprazole are mixed inducers of CYP1A and CYP3A in human hepatocytes in primary culture.

The reduced unsubstituted pteroate moiety is required for folate toxicity of cultured cerebellar granule neurons.

Vasodilator-derived nitric oxide inhibits fetal calf serum- and angiotensin-II-induced growth of renal arteriolar smooth muscle cells.

The effect of adrenergic receptor antagonists on cocaine-induced ventricular fibrillation: alpha but not beta adrenergic receptor antagonists prevent malignant arrhythmias independent of heart rate.

Developmental expression of human microsomal epoxide hydrolase.

Quantification of the calcium antagonism of lacidipine by kinetic analysis.

Effect of vitamin A administration on resistance of rat heart against doxorubicin-induced cardiotoxicity and lethality.

Behavioral and neurochemical studies of opioid effects in the pedunculopontine nucleus and mediodorsal thalamus.

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