Table of Contents

February 1994; 268 (2)
    • K Groen,
    • D D Breimer,
    • E J Jansen,
    • and C F van Bezooijen

    The influence of aging on the metabolism of simultaneously administered hexobarbital enantiomers and antipyrine before and after phenobarbital induction in male rats: a longitudinal study.

    J Pharmacol Exp Ther February 1994 268:531-536
    • T V Dunwiddie and
    • L Diao

    Extracellular adenosine concentrations in hippocampal brain slices and the tonic inhibitory modulation of evoked excitatory responses.

    J Pharmacol Exp Ther February 1994 268:537-545
    • G Mikus,
    • F Bochner,
    • M Eichelbaum,
    • P Horak,
    • A A Somogyi,
    • and S Spector

    Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism.

    J Pharmacol Exp Ther February 1994 268:546-551
    • S Z Wang,
    • S Z Zhu,
    • and E E el-Fakahany

    Efficient coupling of m5 muscarinic acetylcholine receptors to activation of nitric oxide synthase.

    J Pharmacol Exp Ther February 1994 268:552-557
    • C J Tseng,
    • L L Chou,
    • L P Ger,
    • and C S Tung

    Cardiovascular effects of angiotensin III in brainstem nuclei of normotensive and hypertensive rats.

    J Pharmacol Exp Ther February 1994 268:558-564
    • M I Christie and
    • G W Smith

    Cardiovascular and renal hemodynamic effects of A-68930 in the conscious dog: a comparison with fenoldopam.

    J Pharmacol Exp Ther February 1994 268:565-570
    • H Ito,
    • H Sogabe,
    • T Nakarai,
    • Y Sato,
    • M Tomoi,
    • M Kadowaki,
    • M Matsuo,
    • K Tokoro,
    • and K Yoshida

    Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide.

    J Pharmacol Exp Ther February 1994 268:571-575
    • S Suzuki,
    • Y Takata,
    • S Kubota,
    • S Ozaki,
    • and H Kato

    Characterization of the alpha-1 adrenoceptors in the mesenteric vasculature from deoxycorticosterone-salt hypertensive rats: studies on vasoconstriction, radioligand binding and postreceptor events.

    J Pharmacol Exp Ther February 1994 268:576-583
    • M Tsutsui,
    • N Yanagihara,
    • K Minami,
    • H Kobayashi,
    • Y Nakashima,
    • A Kuroiwa,
    • and F Izumi

    C-type natriuretic peptide stimulates catecholamine synthesis through the accumulation of cyclic GMP in cultured bovine adrenal medullary cells.

    J Pharmacol Exp Ther February 1994 268:584-589
    • C Y Chen and
    • C S Chen

    Stereoselective disposition of ibuprofen in patients with renal dysfunction.

    J Pharmacol Exp Ther February 1994 268:590-594
    • E Ronken,
    • A H Mulder,
    • and A N Schoffelmeer

    Chronic activation of mu- and kappa-opioid receptors in cultured catecholaminergic neurons from rat brain causes neuronal supersensitivity without receptor desensitization.

    J Pharmacol Exp Ther February 1994 268:595-599
    • R P Rubin and
    • M A Adolf

    Cyclic AMP regulation of calcium mobilization and amylase release from isolated permeabilized rat parotid cells.

    J Pharmacol Exp Ther February 1994 268:600-606
    • D L Hammond,
    • A Stapelfeld,
    • E J Drower,
    • M A Savage,
    • L Tam,
    • and R H Mazur

    Antinociception produced by oral, subcutaneous or intrathecal administration of SC-39566, an opioid dipeptide arylalkylamide, in the rodent.

    J Pharmacol Exp Ther February 1994 268:607-615
    • R A Mathôt,
    • E A van Schaick,
    • M W Langemeijer,
    • W Soudijn,
    • D D Breimer,
    • A P Ijzerman,
    • and M Danhof

    Pharmacokinetic-pharmacodynamic relationship of the cardiovascular effects of adenosine A1 receptor agonist N6-cyclopentyladenosine in the rat.

    J Pharmacol Exp Ther February 1994 268:616-624
    • R Pohorecki,
    • B J Howard,
    • M Matsushita,
    • P M Stemmer,
    • G L Becker,
    • and D F Landers

    Isoflurane isomers differ in preservation of ATP in anoxic rat hepatocytes.

    J Pharmacol Exp Ther February 1994 268:625-628
    • K A Freeman and
    • R J Tallarida

    A quantitative study of dopamine control in the rat striatum.

    J Pharmacol Exp Ther February 1994 268:629-638
    • T Okamoto,
    • S Mizoguchi,
    • H Terasaki,
    • and T Morioka

    Safety of high-dose of nafamostat mesilate: toxicological study in beagles.

    J Pharmacol Exp Ther February 1994 268:639-644
    • M J Eaton,
    • K J Lookingland,
    • and K E Moore

    Effects of the selective dopaminergic D2 agonist quinelorane on the activity of dopaminergic and noradrenergic neurons projecting to the diencephalon of the rat.

    J Pharmacol Exp Ther February 1994 268:645-652
    • C S Wong,
    • Y F Su,
    • W D Watkins,
    • and K J Chang

    Opioid agonist binding affinity is increased by magnesium in the presence of guanosine diphosphate but decreased by magnesium in the presence of guanyl-5'-yl imidodiphosphate.

    J Pharmacol Exp Ther February 1994 268:653-661
    • K M Hurlbut,
    • R M Maiorino,
    • M Mayersohn,
    • R C Dart,
    • D C Bruce,
    • and H V Aposhian

    Determination and metabolism of dithiol chelating agents. XVI: Pharmacokinetics of 2,3-dimercapto-1-propanesulfonate after intravenous administration to human volunteers.

    J Pharmacol Exp Ther February 1994 268:662-668
    • M Takano,
    • Y Ohishi,
    • M Okuda,
    • M Yasuhara,
    • and R Hori

    Transport of gentamicin and fluid-phase endocytosis markers in the LLC-PK1 kidney epithelial cell line.

    J Pharmacol Exp Ther February 1994 268:669-674
    • Y Wu,
    • H C Rosenberg,
    • T H Chiu,
    • and V Ramsey-Williams

    Regional changes in [3H]zolpidem binding to brain benzodiazepine receptors in flurazepam tolerant rat: comparison with changes in [3H]flunitrazepam binding.

    J Pharmacol Exp Ther February 1994 268:675-682
    • K P Mayfield and
    • L G D'Alecy

    Delta-1 opioid agonist acutely increases hypoxic tolerance.

    J Pharmacol Exp Ther February 1994 268:683-688
    • J E Fox-Threlkeld,
    • E E Daniel,
    • F Christinck,
    • V J Hruby,
    • S Cipris,
    • and Z Woskowska

    Identification of mechanisms and sites of actions of mu and delta opioid receptor activation in the canine intestine.

    J Pharmacol Exp Ther February 1994 268:689-700
    • P E Stewart and
    • D L Hammond

    Activation of spinal delta-1 or delta-2 opioid receptors reduces carrageenan-induced hyperalgesia in the rat.

    J Pharmacol Exp Ther February 1994 268:701-708
    • L A Marshall,
    • J D Winkler,
    • D E Griswold,
    • B Bolognese,
    • A Roshak,
    • C M Sung,
    • E F Webb,
    • and R Jacobs

    Effects of scalaradial, a type II phospholipase A2 inhibitor, on human neutrophil arachidonic acid mobilization and lipid mediator formation.

    J Pharmacol Exp Ther February 1994 268:709-717
    • R L Papke,
    • A G Craig,
    • and S F Heinemann

    Inhibition of nicotinic acetylcholine receptors by bis (2,2,6,6-tetramethyl- 4-piperidinyl) sebacate (Tinuvin 770), an additive to medical plastics.

    J Pharmacol Exp Ther February 1994 268:718-726
    • F C Tortella,
    • L Robles,
    • J M Witkin,
    • and A H Newman

    Novel anticonvulsant analogs of dextromethorphan: improved efficacy, potency, duration and side-effect profile.

    J Pharmacol Exp Ther February 1994 268:727-733
    • J Balthasar and
    • H L Fung

    Utilization of antidrug antibody fragments for the optimization of intraperitoneal drug therapy: studies using digoxin as a model drug.

    J Pharmacol Exp Ther February 1994 268:734-739
    • L A Burns,
    • T L Spriggs,
    • B A Fuchs,
    • and A E Munson

    Gallium arsenide-induced increase in serum corticosterone is not responsible for suppression of the IgM antibody response.

    J Pharmacol Exp Ther February 1994 268:740-746
    • F Bertolino,
    • J P Valentin,
    • M Maffre,
    • B Jover,
    • A M Bessac,
    • and G W John

    Prevention of thromboxane A2 receptor-mediated pulmonary hypertension by a nonpeptide angiotensin II type 1 receptor antagonist.

    J Pharmacol Exp Ther February 1994 268:747-752
    • K K Miller and
    • C R Lupica

    Morphine-induced excitation of pyramidal neurons is inhibited by cholecystokinin in the CA1 region of the rat hippocampal slice.

    J Pharmacol Exp Ther February 1994 268:753-761
    • S Abe,
    • J Nishimura,
    • M Nakamura,
    • and H Kanaide

    Effects of nicorandil on cytosolic calcium concentrations and on tension development in the rabbit femoral artery.

    J Pharmacol Exp Ther February 1994 268:762-771
    • V Ralevic,
    • A Rubino,
    • and G Burnstock

    Prejunctional modulation of sensory-motor nerve-mediated vasodilatation of the rat mesenteric arterial bed by opioid peptides.

    J Pharmacol Exp Ther February 1994 268:772-778
    • H Shimamoto,
    • Y Shimamoto,
    • C Y Kwan,
    • and E E Daniel

    Amplification of 5-hydroxytryptamine-induced contractile responses via 5-hydroxytryptamine receptors and alpha-adrenoceptors in dog mesenteric artery and vein.

    J Pharmacol Exp Ther February 1994 268:779-784
    • D D Mousseau,
    • X Sun,
    • and A A Larson

    An antinociceptive effect of capsaicin in the adult mouse mediated by the NH2-terminus of substance P.

    J Pharmacol Exp Ther February 1994 268:785-790
    • U Bickel,
    • S Yamada,
    • and W M Pardridge

    Synthesis and bioactivity of monobiotinylated DALDA: a mu-specific opioid peptide designed for targeted brain delivery.

    J Pharmacol Exp Ther February 1994 268:791-796
    • K D Adkison,
    • A A Artru,
    • K M Powers,
    • and D D Shen

    Contribution of probenecid-sensitive anion transport processes at the brain capillary endothelium and choroid plexus to the efficient efflux of valproic acid from the central nervous system.

    J Pharmacol Exp Ther February 1994 268:797-805
    • R M Woodward,
    • L Polenzani,
    • and R Miledi

    Effects of fenamates and other nonsteroidal anti-inflammatory drugs on rat brain GABAA receptors expressed in Xenopus oocytes.

    J Pharmacol Exp Ther February 1994 268:806-817
    • A Terzic,
    • A Jahangir,
    • and Y Kurachi

    HOE-234, a second generation K+ channel opener, antagonizes the ATP-dependent gating of cardiac ATP-sensitive K+ channels.

    J Pharmacol Exp Ther February 1994 268:818-825
    • Y Yagil

    The effects of adenosine on water and sodium excretion.

    J Pharmacol Exp Ther February 1994 268:826-835
    • L Fang,
    • R J Knapp,
    • R Horvath,
    • T O Matsunaga,
    • R C Haaseth,
    • V J Hruby,
    • F Porreca,
    • and H I Yamamura

    Characterization of [3H]naltrindole binding to delta opioid receptors in mouse brain and mouse vas deferens: evidence for delta opioid receptor heterogeneity.

    J Pharmacol Exp Ther February 1994 268:836-846
    • C M Handler,
    • T C Piliero,
    • E B Geller,
    • and M W Adler

    Effect of ambient temperature on the ability of mu-, kappa- and delta-selective opioid agonists to modulate thermoregulatory mechanisms in the rat.

    J Pharmacol Exp Ther February 1994 268:847-855
    • H N Bhargava,
    • G A Matwyshyn,
    • A K Rattan,
    • K L Koo,
    • and G A Tejwani

    beta-Endorphin-like immunoreactivity in discrete brain regions, spinal cord, pituitary gland and peripheral tissues of U-50,488H-tolerant and -abstinent rats.

    J Pharmacol Exp Ther February 1994 268:856-861
    • S E Mulroney,
    • C Skudlarek,
    • A Shemer,
    • M D Lumpkin,
    • and K J Kellar

    Tandospirone stimulates prolactin secretion in the rat by an action at serotonin-1A receptors.

    J Pharmacol Exp Ther February 1994 268:862-867
    • I Gorenne,
    • C Labat,
    • J P Gascard,
    • X Norel,
    • R Müller-Peddinghaus,
    • K H Mohrs,
    • W A Taylor,
    • P J Gardiner,
    • and C Brink

    (R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl] acetic acid (BAY x1005), a potent leukotriene synthesis inhibitor: effects on anti-IgE challenge in human airways.

    J Pharmacol Exp Ther February 1994 268:868-872
    • F S Wang,
    • J J Rady,
    • and J M Fujimoto

    Elimination of the antianalgesic action of dynorphin A by spinal transsection in barbital-anesthetized mice.

    J Pharmacol Exp Ther February 1994 268:873-880
    • G F Wilkinson,
    • K McKechnie,
    • I A Dainty,
    • and M R Boarder

    P2Y purinoceptor and nucleotide receptor-induced relaxation of precontracted bovine aortic collateral artery rings: differential sensitivity to suramin and indomethacin.

    J Pharmacol Exp Ther February 1994 268:881-887
    • R J Heaslip,
    • L J Lombardo,
    • J M Golankiewicz,
    • B A Ilsemann,
    • D Y Evans,
    • B D Sickels,
    • J K Mudrick,
    • J Bagli,
    • and B M Weichman

    Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641.

    J Pharmacol Exp Ther February 1994 268:888-896
    • H Hohage,
    • D M Mörth,
    • I U Querl,
    • and J Greven

    Regulation by protein kinase C of the contraluminal transport system for organic cations in rabbit kidney S2 proximal tubules.

    J Pharmacol Exp Ther February 1994 268:897-901
    • A H Campos and
    • J B Calixto

    Mechanisms involved in the contractile responses of kinins in rat portal vein rings: mediation by B1 and B2 receptors.

    J Pharmacol Exp Ther February 1994 268:902-909
    • S J De Kimpe,
    • D Van Heuven-Nolsen,
    • J G van Amsterdam,
    • M W Radomski,
    • and F P Nijkamp

    Induction of nitric oxide release by interferon-gamma inhibits vasodilation and cyclic GMP increase in bovine isolated mesenteric arteries.

    J Pharmacol Exp Ther February 1994 268:910-915
    • I M Maisonneuve and
    • M J Kreek

    Acute tolerance to the dopamine response induced by a binge pattern of cocaine administration in male rats: an in vivo microdialysis study.

    J Pharmacol Exp Ther February 1994 268:916-921
    • A M Birchall,
    • J Bishop,
    • D Bradshaw,
    • A Cline,
    • J Coffey,
    • L H Elliott,
    • V M Gibson,
    • A Greenham,
    • T J Hallam,
    • and W Harris

    Ro 32-0432, a selective and orally active inhibitor of protein kinase C prevents T-cell activation.

    J Pharmacol Exp Ther February 1994 268:922-929
    • Q Xia,
    • J Z Sheng,
    • K K Tai,
    • and T M Wong

    Effects of chronic U50,488H treatment on binding and mechanical responses of the rat hearts.

    J Pharmacol Exp Ther February 1994 268:930-934
    • K D Burris,
    • T M Filtz,
    • S Chumpradit,
    • M P Kung,
    • C Foulon,
    • J G Hensler,
    • H F Kung,
    • and P B Molinoff

    Characterization of [125I](R)-trans-7-hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino] tetralin binding to dopamine D3 receptors in rat olfactory tubercle.

    J Pharmacol Exp Ther February 1994 268:935-942
    • G E De Lander and
    • G J Keil, 2nd

    Antinociception induced by intrathecal coadministration of selective adenosine receptor and selective opioid receptor agonists in mice.

    J Pharmacol Exp Ther February 1994 268:943-951
    • R Kalfin,
    • N Maulik,
    • R M Engelman,
    • G A Cordis,
    • K Milenov,
    • L Kasakov,
    • and D K Das

    Protective role of intracoronary vasoactive intestinal peptide in ischemic and reperfused myocardium.

    J Pharmacol Exp Ther February 1994 268:952-958
    • Q Liu,
    • Y Horio,
    • K Fujimoto,
    • and H Fukui

    Does the [3H]mepyramine binding site represent the histamine H1 receptor? Re-examination of the histamine H1 receptor with quinine.

    J Pharmacol Exp Ther February 1994 268:959-964
    • Y Kojima,
    • T Takahashi,
    • M Fujina,
    • and C Owyang

    Inhibition of cholinergic transmission by opiates in ileal myenteric plexus is mediated by kappa receptor. Involvement of regulatory inhibitory G protein and calcium N-channels.

    J Pharmacol Exp Ther February 1994 268:965-970
    • B Cemerikic,
    • R Zamah,
    • and M S Ahmed

    Opioids regulation of human chorionic gonadotropin release from trophoblast tissue is mediated by gonadotropin releasing hormone.

    J Pharmacol Exp Ther February 1994 268:971-977
    • B Gaston,
    • J M Drazen,
    • A Jansen,
    • D A Sugarbaker,
    • J Loscalzo,
    • W Richards,
    • and J S Stamler

    Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro.

    J Pharmacol Exp Ther February 1994 268:978-984
    • L D Todorov,
    • R A Bjur,
    • and D P Westfall

    Inhibitory and facilitatory effects of purines on transmitter release from sympathetic nerves.

    J Pharmacol Exp Ther February 1994 268:985-989
    • S Guimarães,
    • D Moura,
    • M Q Paiva,
    • and M J Vaz-da-Silva

    Lack of pre- and postjunctional beta adrenoceptor-mediated effects in the canine saphenous vein at birth.

    J Pharmacol Exp Ther February 1994 268:990-995
    • B R Bianchi,
    • T R Miller,
    • D G Witte,
    • and C W Lin

    Novel CCK analogues and bombesin: a detailed analysis between phosphoinositide breakdown and high-dose inhibition of pancreatic enzyme secretion in three rodent species.

    J Pharmacol Exp Ther February 1994 268:996-1002
    • R K Rao,
    • S Levenson,
    • S N Fang,
    • V J Hruby,
    • H I Yamamura,
    • and F Porreca

    Characterization of SNF 9007, a novel cholecystokinin/opoid ligand in mouse ileum in vitro: evidence for involvement of cholecystokininA and cholecystokininB receptors in regulation of ion transport.

    J Pharmacol Exp Ther February 1994 268:1003-1009
    • M Nakajima,
    • A Inui,
    • A Teranishi,
    • M Miura,
    • Y Hirosue,
    • M Okita,
    • N Himori,
    • S Baba,
    • and M Kasuga

    Effects of pancreatic polypeptide family peptides on feeding and learning behavior in mice.

    J Pharmacol Exp Ther February 1994 268:1010-1014
    • L W Zhou,
    • S P Zhang,
    • Z H Qin,
    • and B Weiss

    In vivo administration of an oligodeoxynucleotide antisense to the D2 dopamine receptor messenger RNA inhibits D2 dopamine receptor-mediated behavior and the expression of D2 dopamine receptors in mouse striatum.

    J Pharmacol Exp Ther February 1994 268:1015-1023
    • H Fujisaki,
    • M Mise,
    • Y Ishii,
    • H Yamada,
    • and K Oguri

    Strychnine and brucine as the potent inducers of drug metabolizing enzymes in rat liver: different profiles from phenobarbital on the induction of cytochrome P450 and UDP-glucuronosyltransferase.

    J Pharmacol Exp Ther February 1994 268:1024-1031
    • T Asano,
    • A McWatters,
    • T An,
    • K Matsushima,
    • and E S Kleinerman

    Liposomal muramyl tripeptide up-regulates interleukin-1 alpha, interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 gene expression in human monocytes.

    J Pharmacol Exp Ther February 1994 268:1032-1039
    • A Di Giannuario,
    • S Pieretti,
    • M Luzi,
    • and A Loizzo

    Subchronic treatment with fragments of beta-endorphin prevents electroencephalographic seizures and behavioral alterations induced by centrally administered beta-endorphin in the rabbit.

    J Pharmacol Exp Ther February 1994 268:1040-1050
    • A J Windebank,
    • M D Blexrud,
    • and P C de Groen

    Potential neurotoxicity of the solvent vehicle for cyclosporine.

    J Pharmacol Exp Ther February 1994 268:1051-1056
    • K Varga,
    • N S Gantenberg,
    • and G Kunos

    Endogenous gamma-aminobutyric acid (GABA) mediates ethanol inhibition of vagally mediated reflex bradycardia elicited from aortic baroreceptors.

    J Pharmacol Exp Ther February 1994 268:1057-1062
    • D Felsen,
    • P Ernsberger,
    • P M Sutaria,
    • R J Nejat,
    • P Nguyen,
    • M May,
    • D S Breslin,
    • D N Marion,
    • and E D Vaughan, Jr

    Identification, localization and functional analysis of imidazoline and alpha adrenergic receptors in canine prostate.

    J Pharmacol Exp Ther February 1994 268:1063-1071

Articles

  • ERRATUM

    J Pharmacol Exp Ther February 1994 268:1072
    • M. Quik,
    • B. Collier,
    • G. Goldstein,
    • and T. Audhya

    RETRACTION LETTER

    J Pharmacol Exp Ther February 1994 268:1072
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