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Table of Contents
January 1994; 268 (1)
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J P Zacny
,
J L Lichtor
,
D Flemming
,
D W Coalson
,
and
W K Thompson
A dose-response analysis of the subjective, psychomotor and physiological effects of intravenous morphine in healthy volunteers.
J Pharmacol Exp Ther
January 1994
268
:
1
-
9
Abstract
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I Stadler
,
K C Chadha
,
S Nakeeb
,
C Toumbis
,
J Butsch
,
N Mathur
,
F Munschauer
,
A Vladutiu
,
S K Satchidanand
,
and
J L Ambrus
Pentoxifylline and meclofenamic acid treatment reduces clinical manifestations in a murine model of AIDS.
J Pharmacol Exp Ther
January 1994
268
:
10
-
13
Abstract
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W M Pardridge
,
T Yoshikawa
,
Y S Kang
,
and
L P Miller
Blood-brain barrier transport and brain metabolism of adenosine and adenosine analogs.
J Pharmacol Exp Ther
January 1994
268
:
14
-
18
Abstract
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J Shan
,
X Wu
,
and
P K Pang
Human parathyroid hormone fragment(1-34) and human [Ala25,26,27]parathyroid hormone fragment(1-34): their vascular and intracellular calcium regulating action in vascular smooth muscle cells.
J Pharmacol Exp Ther
January 1994
268
:
19
-
24
Abstract
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X H Xiao
and
J A Bevan
Pharmacological evidence that flow- and potassium-induced contraction of rabbit facial vein may involve the same calcium entry pathway.
J Pharmacol Exp Ther
January 1994
268
:
25
-
31
Abstract
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F J Dumont
,
C Kastner
,
F Iacovone, Jr
,
and
P A Fischer
Quantitative and temporal analysis of the cellular interaction of FK-506 and rapamycin in T-lymphocytes.
J Pharmacol Exp Ther
January 1994
268
:
32
-
41
Abstract
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D L Kachel
and
W J Martin, 2nd
Cyclophosphamide-induced lung toxicity: mechanism of endothelial cell injury.
J Pharmacol Exp Ther
January 1994
268
:
42
-
46
Abstract
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C P France
,
F Medzihradsky
,
and
J H Woods
Comparison of kappa opioids in rhesus monkeys: behavioral effects and receptor binding affinities.
J Pharmacol Exp Ther
January 1994
268
:
47
-
58
Abstract
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C Nuki
,
H Kawasaki
,
K Takasaki
,
and
A Wada
Pharmacological characterization of presynaptic calcitonin gene-related peptide (CGRP) receptors on CGRP-containing vasodilator nerves in rat mesenteric resistance vessels.
J Pharmacol Exp Ther
January 1994
268
:
59
-
64
Abstract
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K Sathirakul
,
H Suzuki
,
T Yamada
,
M Hanano
,
and
Y Sugiyama
Multiple transport systems for organic anions across the bile canalicular membrane.
J Pharmacol Exp Ther
January 1994
268
:
65
-
73
Abstract
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K P Mayfield
and
L G D'Alecy
Delta-1 opioid receptor dependence of acute hypoxic adaptation.
J Pharmacol Exp Ther
January 1994
268
:
74
-
77
Abstract
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D J Brackett
,
D V Gauvin
,
M R Lerner
,
F A Holloway
,
and
M F Wilson
Dose- and time-dependent cardiovascular responses induced by ethanol.
J Pharmacol Exp Ther
January 1994
268
:
78
-
84
Abstract
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J L Ellis
and
B J Undem
Inhibition by capsazepine of resiniferatoxin- and capsaicin-induced contractions of guinea pig trachea.
J Pharmacol Exp Ther
January 1994
268
:
85
-
89
Abstract
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G J Grover
and
P G Sleph
The cardioprotective effects of R 75231 and lidoflazine are not caused by adenosine A1 receptor activation.
J Pharmacol Exp Ther
January 1994
268
:
90
-
96
Abstract
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P J Mueller
and
M M Knuepfer
Coronary vascular effects of cocaine in rats.
J Pharmacol Exp Ther
January 1994
268
:
97
-
103
Abstract
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T R Martin
,
M L Cohen
,
and
J M Drazen
Serotonin-induced pulmonary responses are mediated by the 5-HT2 receptor in the mouse.
J Pharmacol Exp Ther
January 1994
268
:
104
-
109
Abstract
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L J Murphey
and
G D Olsen
Morphine-6-beta-D-glucuronide respiratory pharmacodynamics in the neonatal guinea pig.
J Pharmacol Exp Ther
January 1994
268
:
110
-
116
Abstract
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S Kanwal
and
G J Trachte
Potassium channel inhibitors attenuate neuromodulatory effects of atrial natriuretic factor in the rabbit isolated vas deferens.
J Pharmacol Exp Ther
January 1994
268
:
117
-
123
Abstract
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M Félétou
,
O Dellazuana
,
and
J Duhault
Serotoninergic receptor subtype in coronary artery smooth muscle from young and atherosclerotic rabbit.
J Pharmacol Exp Ther
January 1994
268
:
124
-
132
Abstract
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H Adachi
Effects of E4080, a novel bradycardic agent with a coronary vasodilating property, on coronary and systemic hemodynamics in conscious dogs.
J Pharmacol Exp Ther
January 1994
268
:
133
-
138
Abstract
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N M Munoz
,
A J Vita
,
S P Neeley
,
K McAllister
,
S M Spaethe
,
S R White
,
and
A R Leff
Beta adrenergic modulation of formyl-methionine-leucine-phenylalanine-stimulated secretion of eosinophil peroxidase and leukotriene C4.
J Pharmacol Exp Ther
January 1994
268
:
139
-
143
Abstract
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P Singh
and
M S Roberts
Skin permeability and local tissue concentrations of nonsteroidal anti-inflammatory drugs after topical application.
J Pharmacol Exp Ther
January 1994
268
:
144
-
151
Abstract
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R J Bauer
,
J A Gibbons
,
D P Bell
,
Z P Luo
,
and
J D Young
Nonlinear pharmacokinetics of recombinant human macrophage colony-stimulating factor (M-CSF) in rats.
J Pharmacol Exp Ther
January 1994
268
:
152
-
158
Abstract
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D Oliva
,
M R Accomazzo
,
S Giovanazzi
,
and
S Nicosia
Correlation between leukotriene D4-induced contraction and cytosolic calcium elevation: a quantitative and simultaneous evaluation in smooth muscle.
J Pharmacol Exp Ther
January 1994
268
:
159
-
166
Abstract
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N Lepretre
,
J Mironneau
,
S Arnaudeau
,
Z Tanfin
,
S Harbon
,
G Guillon
,
and
J Ibarrondo
Activation of alpha-1A adrenoceptors mobilizes calcium from the intracellular stores in myocytes from rat portal vein.
J Pharmacol Exp Ther
January 1994
268
:
167
-
174
Abstract
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J L Goudreau
,
K J Lookingland
,
and
K E Moore
5-Hydroxytryptamine2 receptor-mediated regulation of periventricular-hypophysial dopaminergic neuronal activity and the secretion of alpha-melanocyte-stimulating hormone.
J Pharmacol Exp Ther
January 1994
268
:
175
-
179
Abstract
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J F French
,
G A Flynn
,
E L Giroux
,
S Mehdi
,
B Anderson
,
D C Beach
,
J R Koehl
,
and
R C Dage
Characterization of a dual inhibitor of angiotensin I-converting enzyme and neutral endopeptidase.
J Pharmacol Exp Ther
January 1994
268
:
180
-
186
Abstract
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R S Sheldon
,
H J Duff
,
E Thakore
,
and
R J Hill
Class I antiarrhythmic drugs: allosteric inhibitors of [3H] batrachotoxinin binding to rat cardiac sodium channels.
J Pharmacol Exp Ther
January 1994
268
:
187
-
194
Abstract
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P J Tiseo
,
J Cheng
,
G W Pasternak
,
and
C E Inturrisi
Modulation of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist LY274614: assessment of opioid receptor changes.
J Pharmacol Exp Ther
January 1994
268
:
195
-
201
Abstract
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P Nambi
,
M Pullen
,
and
W Spielman
Species differences in the binding characteristics of [125I]IRL-1620, a potent agonist specific for endothelin-B receptors.
J Pharmacol Exp Ther
January 1994
268
:
202
-
207
Abstract
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C Du
,
A Carl
,
T K Smith
,
K M Sanders
,
and
K D Keef
Mechanism of cyclic AMP-induced hyperpolarization in canine colon.
J Pharmacol Exp Ther
January 1994
268
:
208
-
215
Abstract
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G D Pennock
,
J J Milavetz
,
T E Raya
,
J J Bahl
,
S Goldman
,
and
E Morkin
Identification of simple substituted phenols with thyromimetic activity: cardiac effects of 3,5-diiodo-4-hydroxyphenylpropionic acid.
J Pharmacol Exp Ther
January 1994
268
:
216
-
223
Abstract
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Z A Abassi
,
G Kelly
,
E Golomb
,
H Klein
,
and
H R Keiser
Losartan improves the natriuretic response to ANF in rats with high-output heart failure.
J Pharmacol Exp Ther
January 1994
268
:
224
-
230
Abstract
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R Brus
,
R M Kostrzewa
,
K W Perry
,
and
R W Fuller
Supersensitization of the oral response to SKF 38393 in neonatal 6-hydroxydopamine-lesioned rats is eliminated by neonatal 5,7-dihydroxytryptamine treatment.
J Pharmacol Exp Ther
January 1994
268
:
231
-
237
Abstract
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A M Mayer
and
J A Spitzer
Modulation of superoxide generation in in vivo lipopolysaccharide-primed Kupffer cells by staurosporine, okadaic acid, manoalide, arachidonic acid, genistein and sodium orthovanadate.
J Pharmacol Exp Ther
January 1994
268
:
238
-
247
Abstract
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M E Nevins
and
E W Anthony
Antagonists at the serotonin-3 receptor can reduce the fear-potentiated startle response in the rat: evidence for different types of anxiolytic activity?
J Pharmacol Exp Ther
January 1994
268
:
248
-
254
Abstract
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Y Itoh
,
T Ogasawara
,
A Yamazaki
,
Y Ukai
,
A Miura
,
and
K Kimura
Enhancement of noradrenaline release from rat frontal cortex by thyrotropin releasing hormone and its analog, (3R,6R)-6-methyl-5-oxo-3-thiomorpholinylcarbonyl-L-histidyl-L-prolinami de, as studied by intracerebral microdialysis.
J Pharmacol Exp Ther
January 1994
268
:
255
-
261
Abstract
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A O Oyekan
,
J C McGiff
,
P Rosencrantz-Weiss
,
and
J Quilley
Relaxant responses of rabbit aorta: influence of cytochrome P450 inhibitors.
J Pharmacol Exp Ther
January 1994
268
:
262
-
269
Abstract
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A E Fleckenstein
,
K J Lookingland
,
and
K E Moore
Differential effects of histamine on the activity of hypothalamic dopaminergic neurons in the rat.
J Pharmacol Exp Ther
January 1994
268
:
270
-
276
Abstract
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J M Koff
,
L Shuster
,
and
L G Miller
Chronic cocaine administration is associated with behavioral sensitization and time-dependent changes in striatal dopamine transporter binding.
J Pharmacol Exp Ther
January 1994
268
:
277
-
282
Abstract
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D J Morgan
and
J L Huang
Albumin decreases myocardial permeability of unbound quinidine in perfused rat heart.
J Pharmacol Exp Ther
January 1994
268
:
283
-
290
Abstract
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N Mascolo
,
A A Izzo
,
G Autore
,
F Barbato
,
and
F Capasso
Nitric oxide and castor oil-induced diarrhea.
J Pharmacol Exp Ther
January 1994
268
:
291
-
295
Abstract
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N L Benowitz
,
P Jacob, 3rd
,
I Fong
,
and
S Gupta
Nicotine metabolic profile in man: comparison of cigarette smoking and transdermal nicotine.
J Pharmacol Exp Ther
January 1994
268
:
296
-
303
Abstract
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D C Underwood
,
R M Muccitelli
,
M A Luttmann
,
D W Hay
,
T J Torphy
,
and
M A Wasserman
Differential antagonism of airway contractile responses to prostaglandin (PG)D2 and 9 alpha, 11 beta-PGF2 by atropine, SK&F 88046 and SQ 29,548 in the guinea pig.
J Pharmacol Exp Ther
January 1994
268
:
304
-
310
Abstract
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A Horita
,
M A Carino
,
and
Y Ukai
The analeptic effect of methamphetamine in pentobarbital-narcotized rats is mediated via a dopaminergic-cholinergic mechanism.
J Pharmacol Exp Ther
January 1994
268
:
311
-
318
Abstract
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K Kamei
,
H Nabata
,
and
H Kuriyama
Effects of KC 399, a novel ATP-sensitive K+ channel opener, on electrical and mechanical responses in dog tracheal smooth muscle.
J Pharmacol Exp Ther
January 1994
268
:
319
-
327
Abstract
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C Labbé-Jullié
,
I Dubuc
,
A Brouard
,
S Doulut
,
E Bourdel
,
D Pelaprat
,
J Mazella
,
J Martinez
,
W Rostène
,
and
J Costentin
In vivo and in vitro structure-activity studies with peptide and pseudopeptide neurotensin analogs suggest the existence of distinct central neurotensin receptor subtypes.
J Pharmacol Exp Ther
January 1994
268
:
328
-
336
Abstract
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M J Millan
,
H Canton
,
A Gobert
,
F Lejeune
,
J M Rivet
,
K Bervoets
,
M Brocco
,
P Widdowson
,
T Mennini
,
and
V Audinot
Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists.
J Pharmacol Exp Ther
January 1994
268
:
337
-
352
Abstract
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R E Howell
,
B D Sickels
,
S L Woeppel
,
L P Jenkins
,
E B Rubin
,
and
B M Weichman
Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs.
J Pharmacol Exp Ther
January 1994
268
:
353
-
358
Abstract
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A L Curtis
,
D E Grigoriadis
,
M E Page
,
J Rivier
,
and
R J Valentino
Pharmacological comparison of two corticotropin-releasing factor antagonists: in vivo and in vitro studies.
J Pharmacol Exp Ther
January 1994
268
:
359
-
365
Abstract
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A A Larson
and
X Sun
Role of the NH2-terminus of substance P in the inhibition by capsaicin of behavioral sensitization to kainic acid-induced activity in the adult mouse.
J Pharmacol Exp Ther
January 1994
268
:
366
-
371
Abstract
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M J Ryan
,
G W Hicks
,
B L Batley
,
S T Rapundalo
,
W C Patt
,
D G Taylor
,
and
J A Keiser
Effect of an orally active renin inhibitor Cl-992 on blood pressure in normotensive and hypertensive monkeys.
J Pharmacol Exp Ther
January 1994
268
:
372
-
379
Abstract
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H Rollema
,
M Skolnik
,
J D'Engelbronner
,
K Igarashi
,
E Usuki
,
and
N Castagnoli, Jr
MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies.
J Pharmacol Exp Ther
January 1994
268
:
380
-
387
Abstract
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I A de Lannoy
,
R S Mandin
,
and
M Silverman
Renal secretion of vinblastine, vincristine and colchicine in vivo.
J Pharmacol Exp Ther
January 1994
268
:
388
-
395
Abstract
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H Ohjimi
,
K Kushiku
,
H Yamada
,
T Kuwahara
,
Y Kohno
,
and
T Furukawa
Increase of acetylcholine release by nebracetam in dog cardiac sympathetic ganglion.
J Pharmacol Exp Ther
January 1994
268
:
396
-
402
Abstract
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M Inazu
,
H Zhang
,
and
E E Daniel
Properties of the LP-805-induced potassium currents in cultured bovine pulmonary artery endothelial cells.
J Pharmacol Exp Ther
January 1994
268
:
403
-
408
Abstract
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M Chiba
,
K Poon
,
J Hollands
,
and
K S Pang
Glycine conjugation activity of benzoic acid and its acinar localization in the perfused rat liver.
J Pharmacol Exp Ther
January 1994
268
:
409
-
416
Abstract
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S B Freedman
,
S Patel
,
R Marwood
,
F Emms
,
G R Seabrook
,
M R Knowles
,
and
G McAllister
Expression and pharmacological characterization of the human D3 dopamine receptor.
J Pharmacol Exp Ther
January 1994
268
:
417
-
426
Abstract
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J Y Lee
,
S A Buckner
,
M E Brune
,
R B Warner
,
M Winn
,
B De
,
T M Zydowsky
,
T J Opgenorth
,
D J Kerkman
,
and
J F Debernardis
Characterization of antihypertensive activity of ABBOTT-81988, a nonpeptide angiotensin II antagonist in the renal hypertensive rat.
J Pharmacol Exp Ther
January 1994
268
:
427
-
433
Abstract
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J J Liu
,
C I Johnston
,
and
B F Buxton
Synergistic effect of nisoldipine and nitroglycerin on human internal mammary artery.
J Pharmacol Exp Ther
January 1994
268
:
434
-
440
Abstract
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N A Escandon
,
D C Zimmermann
,
and
R B McCall
Characterization of the serotonin1A receptor antagonist activity of WAY-100135 and spiperone.
J Pharmacol Exp Ther
January 1994
268
:
441
-
447
Abstract
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A C Granholm
,
C Bäckman
,
F Bloom
,
T Ebendal
,
G A Gerhardt
,
B Hoffer
,
L Mackerlova
,
L Olson
,
S Söderström
,
and
L R Walus
NGF and anti-transferrin receptor antibody conjugate: short and long-term effects on survival of cholinergic neurons in intraocular septal transplants.
J Pharmacol Exp Ther
January 1994
268
:
448
-
459
Abstract
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M S Seren
,
A Lazzaro
,
C L Yang
,
R Canella
,
M Bassan
,
R Zanoni
,
and
H Manev
Orally administered glycolipid derivative LIGA20 reduces infarct volume and behavioral impairment after focal cerebral ischemia.
J Pharmacol Exp Ther
January 1994
268
:
460
-
465
Abstract
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Y T Shen
,
H Zhang
,
and
S F Vatner
Peripheral vascular effects of beta-3 adrenergic receptor stimulation in conscious dogs.
J Pharmacol Exp Ther
January 1994
268
:
466
-
473
Abstract
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A P Zou
,
Y H Ma
,
Z H Sui
,
P R Ortiz de Montellano
,
J E Clark
,
B S Masters
,
and
R J Roman
Effects of 17-octadecynoic acid, a suicide-substrate inhibitor of cytochrome P450 fatty acid omega-hydroxylase, on renal function in rats.
J Pharmacol Exp Ther
January 1994
268
:
474
-
481
Abstract
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M Miura
,
M G Belvisi
,
and
P J Barnes
Modulation of nonadrenergic noncholinergic neural bronchoconstriction by bradykinin in anesthetized guinea pigs in vivo.
J Pharmacol Exp Ther
January 1994
268
:
482
-
486
Abstract
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A E Cribb
,
E Delaporte
,
S G Kim
,
R F Novak
,
and
K W Renton
Regulation of cytochrome P-4501A and cytochrome P-4502E induction in the rat during the production of interferon alpha/beta.
J Pharmacol Exp Ther
January 1994
268
:
487
-
494
Abstract
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L Tang
,
R D Todd
,
A Heller
,
and
K L O'Malley
Pharmacological and functional characterization of D2, D3 and D4 dopamine receptors in fibroblast and dopaminergic cell lines.
J Pharmacol Exp Ther
January 1994
268
:
495
-
502
Abstract
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A C Costa
and
E X Albuquerque
Dynamics of the actions of tetrahydro-9-aminoacridine and 9-aminoacridine on glutamatergic currents: concentration-jump studies in cultured rat hippocampal neurons.
J Pharmacol Exp Ther
January 1994
268
:
503
-
514
Abstract
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C Thal
,
J el Kahwaji
,
J Loeper
,
M Tinel
,
J Doostzadeh
,
G Labbe
,
J Leclaire
,
P Beaune
,
and
D Pessayre
Administration of high doses of human recombinant interleukin-2 decreases the expression of several cytochromes P-450 in the rat.
J Pharmacol Exp Ther
January 1994
268
:
515
-
521
Abstract
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M J Blake
,
A R Buckley
,
D J Buckley
,
K P LaVoi
,
and
T Bartlett
Neural and endocrine mechanisms of cocaine-induced 70-kDa heat shock protein expression in aorta and adrenal gland.
J Pharmacol Exp Ther
January 1994
268
:
522
-
529
Abstract
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Article
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ERRATUM
J Pharmacol Exp Ther
January 1994
268
:
529
Abstract
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January 1994; 268 (1)
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