Table of Contents

December 1993; 267 (3)

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- Y Shin,
- K J Romstedt,
- D D Miller,
- and D R Feller
Interactions of nonprostanoid trimetoquinol analogs with thromboxane A2/prostaglandin H2 receptors in human platelets, rat vascular endothelial cells and rat vascular smooth muscle cells.
J Pharmacol Exp Ther December 1993 267:1017-1023
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- A Rengasamy and
- R A Johns
Inhibition of nitric oxide synthase by a superoxide generating system.
J Pharmacol Exp Ther December 1993 267:1024-1027
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- R M Edwards,
- E J Stack,
- M Pullen,
- and P Nambi
Endothelin inhibits vasopressin action in rat inner medullary collecting duct via the ETB receptor.
J Pharmacol Exp Ther December 1993 267:1028-1033
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- A Chaudhary,
- R A Lane,
- D Woo,
- and R J Herman
Multiple-dose lorazepam kinetics: shuttling of lorazepam glucuronide between the circulation and the gut during day- and night-time dosing intervals in response to feeding.
J Pharmacol Exp Ther December 1993 267:1034-1038
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- S P Boom and
- F G Russel
Cimetidine uptake and interactions with cationic drugs in freshly isolated proximal tubular cells of the rat.
J Pharmacol Exp Ther December 1993 267:1039-1044
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- A Tosaki,
- P Szerdahelyi,
- R M Engelman,
- and D K Das
Effects of extracellular magnesium manipulation on reperfusion-induced arrhythmias and myocardial ion shifts in isolated ischemic reperfused rat hearts.
J Pharmacol Exp Ther December 1993 267:1045-1053
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- C Blandizzi,
- G Tarkovacs,
- G Natale,
- M Del Tacca,
- and E S Vizi
Functional evidence that [3H]acetylcholine and [3H]noradrenaline release from guinea pig ileal myenteric plexus and noradrenergic terminals is modulated by different presynaptic alpha-2 adrenoceptor subtypes.
J Pharmacol Exp Ther December 1993 267:1054-1060
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- M Gårdmark,
- M Ekblom,
- R Bouw,
- and M Hammarlund-Udenaes
Quantification of effect delay and acute tolerance development to morphine in the rat.
J Pharmacol Exp Ther December 1993 267:1061-1067
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- Z Gregus,
- T Fekete,
- F Varga,
- and C D Klaassen
Effect of valproic acid on glycine conjugation of benzoic acid.
J Pharmacol Exp Ther December 1993 267:1068-1075
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- L Carlsson,
- L Drews,
- G Duker,
- and G Schiller-Linhardt
Attenuation of proarrhythmias related to delayed repolarization by low-dose lidocaine in the anesthetized rabbit.
J Pharmacol Exp Ther December 1993 267:1076-1080
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- J H Li,
- A Shaw,
- and S T Kau
Stereoselective blockade of amphibian epithelial sodium channels by amiloride analogs.
J Pharmacol Exp Ther December 1993 267:1081-1084
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- A Tsuji,
- A Saheki,
- I Tamai,
- and T Terasaki
Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier.
J Pharmacol Exp Ther December 1993 267:1085-1090
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- Y X Wang,
- C I Poon,
- and C C Pang
Vascular pharmacodynamics of NG-nitro-L-arginine methyl ester in vitro and in vivo.
J Pharmacol Exp Ther December 1993 267:1091-1099
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- A Rubino,
- V Ralevic,
- and G Burnstock
The P1-purinoceptors that mediate the prejunctional inhibitory effect of adenosine on capsaicin-sensitive nonadrenergic noncholinergic neurotransmission in the rat mesenteric arterial bed are of the A1 subtype.
J Pharmacol Exp Ther December 1993 267:1100-1104
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- M A Hossain and
- N Weiner
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
J Pharmacol Exp Ther December 1993 267:1105-1111
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- A Zembowicz,
- R J Hatchett,
- W Radziszewski,
- and R J Gryglewski
Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.
J Pharmacol Exp Ther December 1993 267:1112-1118
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- M D Sauro and
- B Thomas
Tyrphostin attenuates platelet-derived growth factor-induced contraction in aortic smooth muscle through inhibition of protein tyrosine kinase(s).
J Pharmacol Exp Ther December 1993 267:1119-1125
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- C S Bockman,
- W B Jeffries,
- and P W Abel
Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium.
J Pharmacol Exp Ther December 1993 267:1126-1133
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- R Chàvez,
- C Bravo,
- C Zazueta,
- J Pichardo,
- A Uribe,
- N Corona,
- H Reyes-Vivas,
- C González,
- and E Chàvez
Ionophoretic-like properties of ketorolac for calcium.
J Pharmacol Exp Ther December 1993 267:1134-1139
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- J L Boyer,
- E R Lazarowski,
- X H Chen,
- and T K Harden
Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase.
J Pharmacol Exp Ther December 1993 267:1140-1146
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- D Raeburn and
- J A Karlsson
Effects of isoenzyme-selective inhibitors of cyclic nucleotide phosphodiesterase on microvascular leak in guinea pig airways in vivo.
J Pharmacol Exp Ther December 1993 267:1147-1152
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- K W Kim and
- B M Cox
Inhibition of norepinephrine release from rat cortex slices by opioids: differences among agonists in sensitivities to antagonists suggest receptor heterogeneity.
J Pharmacol Exp Ther December 1993 267:1153-1160
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- N Priymenko,
- J P Ferre,
- A Rascol,
- G Costes,
- and P L Toutain
Migrating motor complex of the intestine and absorption of a biliary excreted drug in the dog.
J Pharmacol Exp Ther December 1993 267:1161-1167
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- C K Buckner,
- N Liberati,
- D Dea,
- D Lengel,
- C Stinson-Fisher,
- J Campbell,
- S Miller,
- A Shenvi,
- and R D Krell
Differential blockade by tachykinin NK1 and NK2 receptor antagonists of bronchoconstriction induced by direct-acting agonists and the indirect-acting mimetics capsaicin, serotonin and 2-methyl-serotonin in the anesthetized guinea pig.
J Pharmacol Exp Ther December 1993 267:1168-1175
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- Y Chen and
- D B Hoover
Pharmacological characterization of the pressor response to tachykinins in isolated perfused rat kidney.
J Pharmacol Exp Ther December 1993 267:1176-1180
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- P A Cossum,
- H Sasmor,
- D Dellinger,
- L Truong,
- L Cummins,
- S R Owens,
- P M Markham,
- J P Shea,
- and S Crooke
Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.
J Pharmacol Exp Ther December 1993 267:1181-1190
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- L P Feigen,
- N S Nicholson,
- L W King,
- J G Campion,
- F S Tjoeng,
- and S G Panzer-Knodle
SC-49992, a mimetic of the peptide arginine-glycine-aspartic acid-phenylalanine that blocks platelet aggregation, enhances recombinant tissue plasminogen activator-induced thrombolysis and prevents reocclusion in a canine model of coronary artery thrombosis.
J Pharmacol Exp Ther December 1993 267:1191-1197
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- T W Vickroy,
- W L Malphurs,
- and N C Defiebre
Absence of receptor reserve at hippocampal muscarinic autoreceptors which inhibit stimulus-dependent acetylcholine release.
J Pharmacol Exp Ther December 1993 267:1198-1204
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- U D Sohn,
- K M Harnett,
- G De Petris,
- J Behar,
- and P Biancani
Distinct muscarinic receptors, G proteins and phospholipases in esophageal and lower esophageal sphincter circular muscle.
J Pharmacol Exp Ther December 1993 267:1205-1214
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- L Turski and
- D N Stephens
Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam.
J Pharmacol Exp Ther December 1993 267:1215-1220
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- R M Maiorino,
- M M Aposhian,
- Z F Xu,
- Y Li,
- R L Polt,
- and H V Aposhian
Determination and metabolism of dithiol chelating agents. XV. The meso-2,3-dimercaptosuccinic acid-cysteine (1:2) mixed disulfide, a major urinary metabolite of DMSA in the human, increases the urinary excretion of lead in the rat.
J Pharmacol Exp Ther December 1993 267:1221-1226
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- K H Dykstra,
- A Arya,
- D M Arriola,
- P M Bungay,
- P F Morrison,
- and R L Dedrick
Microdialysis study of zidovudine (AZT) transport in rat brain.
J Pharmacol Exp Ther December 1993 267:1227-1236
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- W A Schumacher,
- T E Steinbacher,
- C L Heran,
- S M Seiler,
- I M Michel,
- and M L Ogletree
Comparison of thrombin active site and exosite inhibitors and heparin in experimental models of arterial and venous thrombosis and bleeding.
J Pharmacol Exp Ther December 1993 267:1237-1242
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- W A Van Sickle,
- P K Wilson,
- M W Wannamaker,
- J R Cooper,
- M A Flanagan,
- J R McCarthy,
- P Bey,
- and R L Jackson
An alternative mechanism for the inhibition of cholesterol biosynthesis in HepG2 cells by N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol (MDL 28,815).
J Pharmacol Exp Ther December 1993 267:1243-1249
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- M T Piascik,
- M S Smith,
- K W Barron,
- and E E Soltis
The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat.
J Pharmacol Exp Ther December 1993 267:1250-1255
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- J B Richards,
- K E Sabol,
- and L S Seiden
Fluoxetine prevents the disruptive effects of fenfluramine on differential-reinforcement-of-low-rate 72-second schedule performance.
J Pharmacol Exp Ther December 1993 267:1256-1263
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- M Goto,
- J J Lemasters,
- and R G Thurman
Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat.
J Pharmacol Exp Ther December 1993 267:1264-1268
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- E R Butelman,
- S S Negus,
- Y Ai,
- B R de Costa,
- and J H Woods
Kappa opioid antagonist effects of systemically administered nor-binaltorphimine in a thermal antinociception assay in rhesus monkeys.
J Pharmacol Exp Ther December 1993 267:1269-1276
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- M Asano,
- K Masuzawa-Ito,
- T Matsuda,
- Y Suzuki,
- H Oyama,
- M Shibuya,
- and K Sugita
Functional role of charybdotoxin-sensitive K+ channels in the resting state of cerebral, coronary and mesenteric arteries of the dog.
J Pharmacol Exp Ther December 1993 267:1277-1285
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- D C Bode,
- L T Hamel,
- and M B Wax
Distinct profiles of phosphodiesterase isozymes in cultured cells derived from nonpigmented and pigmented ocular ciliary epithelium.
J Pharmacol Exp Ther December 1993 267:1286-1291
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- D Y Li,
- D R Varma,
- T K Chatterjee,
- H Fernandez,
- D Abran,
- and S Chemtob
Fewer PGE2 and PGF2 alpha receptors in brain synaptosomes of newborn than of adult pigs.
J Pharmacol Exp Ther December 1993 267:1292-1297
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- B Christensen and
- P M Ueland
Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.
J Pharmacol Exp Ther December 1993 267:1298-1303
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- E K Jackson,
- W A Herzer,
- and F Suzuki
KF17837 is an A2 adenosine receptor antagonist in vivo.
J Pharmacol Exp Ther December 1993 267:1304-1310
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- C A Sannerud,
- R J Marley,
- S L Serdikoff,
- A J Alastra,
- C Cohen,
- and S R Goldberg
Tolerance to the behavioral effects of chlordiazepoxide: pharmacological and biochemical selectivity.
J Pharmacol Exp Ther December 1993 267:1311-1320
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- H A Thomas,
- N Ling,
- E T Wei,
- F Berree,
- A Cobas,
- and H Rapoport
Novel anti-inflammatory undecapeptides that contain anisolyated glutamic acid derivatives.
J Pharmacol Exp Ther December 1993 267:1321-1326
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- S A Khan,
- W R Mathews,
- and K D Meisheri
Role of calcium-activated K+ channels in vasodilation induced by nitroglycerine, acetylcholine and nitric oxide.
J Pharmacol Exp Ther December 1993 267:1327-1335
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- M C Hernandez,
- L R Flores,
- and B M Bayer
Immunosuppression by morphine is mediated by central pathways.
J Pharmacol Exp Ther December 1993 267:1336-1341
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- P L Martin,
- M Kelly,
- and N J Cusack
(-)-2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0923), a selective D2 dopamine receptor agonist demonstrates the presence of D2 dopamine receptors in the mouse vas deferens but not in the rat vas deferens.
J Pharmacol Exp Ther December 1993 267:1342-1348
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- J R Clague,
- R Harvey,
- and G A Langer
Protamine and other polycationic drugs inhibit calcium leak in cardiac cells during metabolic inhibition and free radical exposure.
J Pharmacol Exp Ther December 1993 267:1349-1354
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- A Tosaki,
- P Szerdahelyi,
- R M Engelman,
- and D K Das
Potassium channel openers and blockers: do they possess proarrhythmic or antiarrhythmic activity in ischemic and reperfused rat hearts?
J Pharmacol Exp Ther December 1993 267:1355-1362
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- P Thatikunta,
- S Chakder,
- and S Rattan
Nitric oxide synthase inhibitor inhibits catecholamines release caused by hypogastric sympathetic nerve stimulation.
J Pharmacol Exp Ther December 1993 267:1363-1368
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- F Costa and
- I Biaggioni
Adenosine activates afferent fibers in the forearm, producing sympathetic stimulation in humans.
J Pharmacol Exp Ther December 1993 267:1369-1374
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- V Casolaro,
- S Meliota,
- O Marino,
- V Patella,
- A de Paulis,
- G Guidi,
- and G Marone
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
J Pharmacol Exp Ther December 1993 267:1375-1385
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- D B Vaupel,
- W R Lange,
- and E D London
Effects of verapamil on morphine-induced euphoria, analgesia and respiratory depression in humans.
J Pharmacol Exp Ther December 1993 267:1386-1394
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- P Li and
- D D Smyth
Suppressed renal response to 2,6-dimethyl clonidine but not clonidine in one kidney-one clip hypertensive rats.
J Pharmacol Exp Ther December 1993 267:1395-1400
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- M Runge-Morris and
- R F Novak
Effects of phenelzine and hydralazine on hydrogen peroxide production and proteolysis in human red blood cells.
J Pharmacol Exp Ther December 1993 267:1401-1406
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- G B Weiss,
- B Sturm,
- and N R Levens
Rapid reversal of angiotensin I-induced contractions in rat carotid arteries after acute and chronic treatment with the angiotensin-converting enzyme inhibitor, 3-[(5-amino-1-carboxy-1S-pentyl)amino]2,3,4,5-tetrahydro-2-oxo- 3S-1H-1-benzazepena-1-acetic acid (CGS 16617).
J Pharmacol Exp Ther December 1993 267:1407-1413
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- L G Aguayo and
- J M Alarcón
Modulation of the developing rat sympathetic GABAA receptor by Zn++, benzodiazepines, barbiturates and ethanol.
J Pharmacol Exp Ther December 1993 267:1414-1422
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- A F Hajj-Ali and
- P C Wong
Beta adrenoceptor blockade in rabbit inhibits the renin-releasing effect of AT1 receptor antagonist losartan.
J Pharmacol Exp Ther December 1993 267:1423-1427
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- R P Simon,
- M Niro,
- and R Gwinn
Brain acidosis induced by hypercarbic ventilation attenuates focal ischemic injury.
J Pharmacol Exp Ther December 1993 267:1428-1431
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- A M Andrews and
- D L Murphy
2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission.
J Pharmacol Exp Ther December 1993 267:1432-1439
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- L T Wong,
- M R Escobar,
- D D Smyth,
- and D S Sitar
Gender-associated differences in rat renal tubular amantadine transport and absence of stereoselective transport inhibition by quinine and quinidine in distal tubules.
J Pharmacol Exp Ther December 1993 267:1440-1444
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- N H Chen and
- M E Reith
Dopamine and serotonin release-regulating autoreceptor sensitivity in A9/A10 cell body and terminal areas after withdrawal of rats from continuous infusion of cocaine.
J Pharmacol Exp Ther December 1993 267:1445-1453
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- R C Boldry,
- T N Chase,
- and T M Engber
Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions.
J Pharmacol Exp Ther December 1993 267:1454-1459
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- M E McNerney and
- H H Szeto
Prenatal nicotine exposure evokes changes in the incidence and degree of fetal electrocortical activation.
J Pharmacol Exp Ther December 1993 267:1460-1469
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- S D Comer,
- S T Lac,
- L K Curtis,
- and M E Carroll
Effects of buprenorphine and naltrexone on reinstatement of cocaine-reinforced responding in rats.
J Pharmacol Exp Ther December 1993 267:1470-1477
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- P Aagaard and
- M McKinney
Pharmacological characterization of the novel cholinomimetic L-689,660 at cloned and native brain muscarinic receptors.
J Pharmacol Exp Ther December 1993 267:1478-1483
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- P Riekkinen, Jr,
- M Riekkinen,
- and J Sirviö
Cholinergic drugs regulate passive avoidance performance via the amygdala.
J Pharmacol Exp Ther December 1993 267:1484-1492
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- J E Piletz and
- K Sletten
Nonadrenergic imidazoline binding sites on human platelets.
J Pharmacol Exp Ther December 1993 267:1493-1502
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- O Traub and
- R C Webb
Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.
J Pharmacol Exp Ther December 1993 267:1503-1508
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- H Kovacic,
- P Gallice,
- M Sarrazin,
- and A Crevat
Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.
J Pharmacol Exp Ther December 1993 267:1509-1514
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- P Chan,
- J W Langston,
- and D A Di Monte
MK-801 temporarily prevents MPTP-induced acute dopamine depletion and MPP+ elimination in the mouse striatum.
J Pharmacol Exp Ther December 1993 267:1515-1520
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- E Leung,
- J M Rapp,
- L K Walsh,
- K D Zeitung,
- and R M Eglen
Characterization of angiotensin II receptors in smooth muscle preparations of the guinea pig in vitro.
J Pharmacol Exp Ther December 1993 267:1521-1528
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- W R Mathews and
- S W Kerr
Biological activity of S-nitrosothiols: the role of nitric oxide.
J Pharmacol Exp Ther December 1993 267:1529-1537
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- K Yoshida,
- A Morimoto,
- T Makisumi,
- and N Murakami
Cardiovascular, thermal and behavioral sensitization to methamphetamine in freely moving rats.
J Pharmacol Exp Ther December 1993 267:1538-1543
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- M Yamada,
- A Terzic,
- I Findlay,
- A Jahangir,
- W K Shen,
- and Y Kurachi
YM934, a novel K+ channel opener, activates ATP-sensitive K+ channels in cardiac myocytes.
J Pharmacol Exp Ther December 1993 267:1544-1549
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- R Rabinovici,
- P J Bugelski,
- K M Esser,
- L M Hillegass,
- D E Griswold,
- J Vernick,
- and G Feuerstein
Tumor necrosis factor-alpha mediates endotoxin-induced lung injury in platelet activating factor-primed rats.
J Pharmacol Exp Ther December 1993 267:1550-1557
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- K Fischer-Stenger,
- D A Dove Pettit,
- and G A Cabral
Delta 9-tetrahydrocannabinol inhibition of tumor necrosis factor-alpha: suppression of post-translational events.
J Pharmacol Exp Ther December 1993 267:1558-1565
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- K M Linner,
- S E Nicol,
- and B M Sharp
IL-1 beta modulates the concanavalin-A-induced expression of proenkephalin A mRNA in murine thymocytes.
J Pharmacol Exp Ther December 1993 267:1566-1572
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- M E Lajiness,
- C L Chio,
- and R M Huff
D2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: relationship to dopamine stimulation of tyrosine phosphorylations.
J Pharmacol Exp Ther December 1993 267:1573-1581
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- Y Qian,
- B Hitzemann,
- G L Yount,
- J D White,
- and R Hitzemann
D1 and D2 dopamine receptor turnover and D2 messenger RNA levels in the neuroleptic-responsive and the neuroleptic nonresponsive lines of mice.
J Pharmacol Exp Ther December 1993 267:1582-1590
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Current Issue

November 2009, 331 (2)

Interactions of nonprostanoid trimetoquinol analogs with thromboxane A2/prostaglandin H2 receptors in human platelets, rat vascular endothelial cells and rat vascular smooth muscle cells.

Inhibition of nitric oxide synthase by a superoxide generating system.

Endothelin inhibits vasopressin action in rat inner medullary collecting duct via the ETB receptor.

Multiple-dose lorazepam kinetics: shuttling of lorazepam glucuronide between the circulation and the gut during day- and night-time dosing intervals in response to feeding.

Cimetidine uptake and interactions with cationic drugs in freshly isolated proximal tubular cells of the rat.

Effects of extracellular magnesium manipulation on reperfusion-induced arrhythmias and myocardial ion shifts in isolated ischemic reperfused rat hearts.

Functional evidence that [3H]acetylcholine and [3H]noradrenaline release from guinea pig ileal myenteric plexus and noradrenergic terminals is modulated by different presynaptic alpha-2 adrenoceptor subtypes.

Quantification of effect delay and acute tolerance development to morphine in the rat.

Effect of valproic acid on glycine conjugation of benzoic acid.

Attenuation of proarrhythmias related to delayed repolarization by low-dose lidocaine in the anesthetized rabbit.

Stereoselective blockade of amphibian epithelial sodium channels by amiloride analogs.

Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier.

Vascular pharmacodynamics of NG-nitro-L-arginine methyl ester in vitro and in vivo.

The P1-purinoceptors that mediate the prejunctional inhibitory effect of adenosine on capsaicin-sensitive nonadrenergic noncholinergic neurotransmission in the rat mesenteric arterial bed are of the A1 subtype.

Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.

Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.

Tyrphostin attenuates platelet-derived growth factor-induced contraction in aortic smooth muscle through inhibition of protein tyrosine kinase(s).

Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium.

Ionophoretic-like properties of ketorolac for calcium.

Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase.

Effects of isoenzyme-selective inhibitors of cyclic nucleotide phosphodiesterase on microvascular leak in guinea pig airways in vivo.

Inhibition of norepinephrine release from rat cortex slices by opioids: differences among agonists in sensitivities to antagonists suggest receptor heterogeneity.

Migrating motor complex of the intestine and absorption of a biliary excreted drug in the dog.

Differential blockade by tachykinin NK1 and NK2 receptor antagonists of bronchoconstriction induced by direct-acting agonists and the indirect-acting mimetics capsaicin, serotonin and 2-methyl-serotonin in the anesthetized guinea pig.

Pharmacological characterization of the pressor response to tachykinins in isolated perfused rat kidney.

Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.

SC-49992, a mimetic of the peptide arginine-glycine-aspartic acid-phenylalanine that blocks platelet aggregation, enhances recombinant tissue plasminogen activator-induced thrombolysis and prevents reocclusion in a canine model of coronary artery thrombosis.

Absence of receptor reserve at hippocampal muscarinic autoreceptors which inhibit stimulus-dependent acetylcholine release.

Distinct muscarinic receptors, G proteins and phospholipases in esophageal and lower esophageal sphincter circular muscle.

Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam.

Determination and metabolism of dithiol chelating agents. XV. The meso-2,3-dimercaptosuccinic acid-cysteine (1:2) mixed disulfide, a major urinary metabolite of DMSA in the human, increases the urinary excretion of lead in the rat.

Microdialysis study of zidovudine (AZT) transport in rat brain.

Comparison of thrombin active site and exosite inhibitors and heparin in experimental models of arterial and venous thrombosis and bleeding.

An alternative mechanism for the inhibition of cholesterol biosynthesis in HepG2 cells by N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol (MDL 28,815).

The regulation of regional hemodynamics by alpha-1 adrenoceptor subtypes in the conscious rat.

Fluoxetine prevents the disruptive effects of fenfluramine on differential-reinforcement-of-low-rate 72-second schedule performance.

Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat.

Kappa opioid antagonist effects of systemically administered nor-binaltorphimine in a thermal antinociception assay in rhesus monkeys.

Functional role of charybdotoxin-sensitive K+ channels in the resting state of cerebral, coronary and mesenteric arteries of the dog.

Distinct profiles of phosphodiesterase isozymes in cultured cells derived from nonpigmented and pigmented ocular ciliary epithelium.

Fewer PGE2 and PGF2 alpha receptors in brain synaptosomes of newborn than of adult pigs.

Methionine synthase inactivation by nitrous oxide during methionine loading of normal human fibroblasts. Homocysteine remethylation as determinant of enzyme inactivation and homocysteine export.

KF17837 is an A2 adenosine receptor antagonist in vivo.

Tolerance to the behavioral effects of chlordiazepoxide: pharmacological and biochemical selectivity.

Novel anti-inflammatory undecapeptides that contain anisolyated glutamic acid derivatives.

Role of calcium-activated K+ channels in vasodilation induced by nitroglycerine, acetylcholine and nitric oxide.

Immunosuppression by morphine is mediated by central pathways.

(-)-2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0923), a selective D2 dopamine receptor agonist demonstrates the presence of D2 dopamine receptors in the mouse vas deferens but not in the rat vas deferens.

Protamine and other polycationic drugs inhibit calcium leak in cardiac cells during metabolic inhibition and free radical exposure.

Potassium channel openers and blockers: do they possess proarrhythmic or antiarrhythmic activity in ischemic and reperfused rat hearts?

Nitric oxide synthase inhibitor inhibits catecholamines release caused by hypogastric sympathetic nerve stimulation.

Adenosine activates afferent fibers in the forearm, producing sympathetic stimulation in humans.

Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.

Effects of verapamil on morphine-induced euphoria, analgesia and respiratory depression in humans.

Suppressed renal response to 2,6-dimethyl clonidine but not clonidine in one kidney-one clip hypertensive rats.

Effects of phenelzine and hydralazine on hydrogen peroxide production and proteolysis in human red blood cells.

Rapid reversal of angiotensin I-induced contractions in rat carotid arteries after acute and chronic treatment with the angiotensin-converting enzyme inhibitor, 3-[(5-amino-1-carboxy-1S-pentyl)amino]2,3,4,5-tetrahydro-2-oxo- 3S-1H-1-benzazepena-1-acetic acid (CGS 16617).

Modulation of the developing rat sympathetic GABAA receptor by Zn++, benzodiazepines, barbiturates and ethanol.

Beta adrenoceptor blockade in rabbit inhibits the renin-releasing effect of AT1 receptor antagonist losartan.

Brain acidosis induced by hypercarbic ventilation attenuates focal ischemic injury.

2'-NH2-MPTP in Swiss Webster mice: evidence for long-term (6-month) depletions in cortical and hippocampal serotonin and norepinephrine, differential protection by selective uptake inhibitors or clorgyline and functional changes in central serotonin neurotransmission.

Gender-associated differences in rat renal tubular amantadine transport and absence of stereoselective transport inhibition by quinine and quinidine in distal tubules.

Dopamine and serotonin release-regulating autoreceptor sensitivity in A9/A10 cell body and terminal areas after withdrawal of rats from continuous infusion of cocaine.

Influence of previous exposure to levodopa on the interaction between dizocilpine and dopamine D1 and D2 agonists in rats with 6-hydroxydopamine-induced lesions.

Prenatal nicotine exposure evokes changes in the incidence and degree of fetal electrocortical activation.

Effects of buprenorphine and naltrexone on reinstatement of cocaine-reinforced responding in rats.

Pharmacological characterization of the novel cholinomimetic L-689,660 at cloned and native brain muscarinic receptors.

Cholinergic drugs regulate passive avoidance performance via the amygdala.

Nonadrenergic imidazoline binding sites on human platelets.

Angiotensin-converting enzyme inhibition during development alters calcium regulation in adult hypertensive rats.

Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.

MK-801 temporarily prevents MPTP-induced acute dopamine depletion and MPP+ elimination in the mouse striatum.

Characterization of angiotensin II receptors in smooth muscle preparations of the guinea pig in vitro.

Biological activity of S-nitrosothiols: the role of nitric oxide.

Cardiovascular, thermal and behavioral sensitization to methamphetamine in freely moving rats.

YM934, a novel K+ channel opener, activates ATP-sensitive K+ channels in cardiac myocytes.

Tumor necrosis factor-alpha mediates endotoxin-induced lung injury in platelet activating factor-primed rats.

Delta 9-tetrahydrocannabinol inhibition of tumor necrosis factor-alpha: suppression of post-translational events.

IL-1 beta modulates the concanavalin-A-induced expression of proenkephalin A mRNA in murine thymocytes.