Table of Contents

August 1993; 266 (2)

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- J M Witkin,
- P Terry,
- M Menkel,
- P Hickey,
- M Pontecorvo,
- J Ferkany,
- and J L Katz
Effects of the selective sigma receptor ligand, 6-[6-(4-hydroxypiperidinyl)hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine.
J Pharmacol Exp Ther August 1993 266:473-482
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- A Delaunois,
- P Gustin,
- and M Ansay
Role of neuropeptides in acetylcholine-induced edema in isolated and perfused rabbit lungs.
J Pharmacol Exp Ther August 1993 266:483-491
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- M Chiba and
- K S Pang
Effect of protein binding on 4-methylumbelliferyl sulfate desulfation kinetics in perfused rat liver.
J Pharmacol Exp Ther August 1993 266:492-499
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- Y K Kim,
- T I Kim,
- D K Jung,
- J S Jung,
- and S H Lee
Inhibition of H+/organic cation antiport by carboxyl reagents in rabbit renal brush-border membrane vesicles.
J Pharmacol Exp Ther August 1993 266:500-505
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- R M Edwards and
- E J Stack
Angiotensin II inhibits glomerular adenylate cyclase via the angiotensin II receptor subtype 1 (AT1).
J Pharmacol Exp Ther August 1993 266:506-510
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- P Golino,
- G Ambrosio,
- P Gresele,
- I Pascucci,
- M Ragni,
- E Russolillo,
- G B Leproux,
- and M Chiariello
The in vivo antiplatelet effects of thromboxane A2 synthase inhibitors are potentiated by simultaneous thromboxane A2/prostaglandin H2 receptor blockade.
J Pharmacol Exp Ther August 1993 266:511-517
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- D G Winder,
- T Smith,
- and P J Conn
Pharmacological differentiation of metabotropic glutamate receptors coupled to potentiation of cyclic adenosine monophosphate responses and phosphoinositide hydrolysis.
J Pharmacol Exp Ther August 1993 266:518-525
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- D V Widzowski and
- D A Cory-Slechta
Apparent mediation of the stimulus properties of a low dose of quinpirole by dopaminergic autoreceptors.
J Pharmacol Exp Ther August 1993 266:526-534
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- R M Eglen,
- C H Lee,
- W L Smith,
- L G Johnson,
- R L Whiting,
- and S S Hegde
RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo.
J Pharmacol Exp Ther August 1993 266:535-543
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- P Paakkari,
- I Paakkari,
- S Vonhof,
- G Feuerstein,
- and A L Sirén
Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors?
J Pharmacol Exp Ther August 1993 266:544-550
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- L R McLean,
- J E Lewis,
- K A Hagaman,
- T J Owen,
- and E R Matthews
Role of the hydrophobic face of amphipathic alpha-helical peptides in synthetic pulmonary surfactants.
J Pharmacol Exp Ther August 1993 266:551-556
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- A Imperato,
- M C Obinu,
- M A Casu,
- M S Mascia,
- L Dazzi,
- and G L Gessa
Evidence that neuroleptics increase striatal acetylcholine release through stimulation of dopamine D1 receptors.
J Pharmacol Exp Ther August 1993 266:557-562
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- J J Woodward and
- S Cueto
Effects of the putative polyamine antagonists diethylenetriamine and 1,10-diaminodecane on N-methyl-D-aspartic acid-stimulated [3H]norepinephrine release from rat hippocampal slices.
J Pharmacol Exp Ther August 1993 266:563-569
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- G Wong,
- P Skolnick,
- J L Katz,
- and J M Witkin
Transduction of a discriminative stimulus through a diazepam-insensitive gamma-aminobutyric acidA receptor.
J Pharmacol Exp Ther August 1993 266:570-576
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- T H Kramer,
- P Davis,
- V J Hruby,
- T F Burks,
- and F Porreca
In vitro potency, affinity and agonist efficacy of highly selective delta opioid receptor ligands.
J Pharmacol Exp Ther August 1993 266:577-584
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- P M Callahan and
- K A Cunningham
Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats.
J Pharmacol Exp Ther August 1993 266:585-592
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- A V Terry, Jr,
- L A Silks, 3rd,
- R B Dunlap,
- J D Odom,
- and J W Kosh
Further biological activities of the novel choline analogs selenonium choline and acetylselenonium choline.
J Pharmacol Exp Ther August 1993 266:593-601
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- M M el-Mas and
- A A Abdel-Rahman
Role of NMDA and non-NMDA receptors in the nucleus tractus solitarius in the depressant effect of ethanol on baroreflexes.
J Pharmacol Exp Ther August 1993 266:602-610
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- B Amoah-Apraku,
- J Xu,
- J Y Lu,
- A Pelleg,
- R F Bruns,
- and L Belardinelli
Selective potentiation by an A1 adenosine receptor enhancer of the negative dromotropic action of adenosine in the guinea pig heart.
J Pharmacol Exp Ther August 1993 266:611-617
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- J Chamberlain,
- S J Offord,
- B B Wolfe,
- L S Tyau,
- H L Wang,
- and A Frazer
Potency of 5-hydroxytryptamine1a agonists to inhibit adenylyl cyclase activity is a function of affinity for the "low-affinity" state of [3H]8-hydroxy-N,N-dipropylaminotetralin ([3H]8-OH-DPAT) binding.
J Pharmacol Exp Ther August 1993 266:618-625
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- R Sorrentino,
- L Sorrentino,
- and A Pinto
Effect of some products of protein catabolism on the endothelium-dependent and -independent relaxation of rabbit thoracic aorta rings.
J Pharmacol Exp Ther August 1993 266:626-633
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- R M Broad and
- M A Cook
Inhibition of neurotransmitter release from enteric nerve endings by 2-[p-(carboxyethyl)-phenethylamino]-5'-N-ethylcarboxamido-adenosine (CGS-21680) and related adenosine analogs: lack of simple competition by antagonists.
J Pharmacol Exp Ther August 1993 266:634-641
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- E E Soltis
Alterations in vascular structure and function after short-term losartan treatment in spontaneously hypertensive rats.
J Pharmacol Exp Ther August 1993 266:642-646
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- R K Rao,
- H H Chang,
- S Levenson,
- F Porreca,
- P M Brannon,
- T P Davis,
- and O Koldovsky
Ontogenic differences in the inhibition of gastric acid secretion by epidermal growth factor.
J Pharmacol Exp Ther August 1993 266:647-654
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- K D Meisheri,
- S J Humphrey,
- S A Khan,
- L A Cipkus-Dubray,
- M P Smith,
- and A W Jones
4-morpholinecarboximidine-N-1-adamantyl-N'-cyclohexylhydrochloride (U-37883A): pharmacological characterization of a novel antagonist of vascular ATP-sensitive K+ channel openers.
J Pharmacol Exp Ther August 1993 266:655-665
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- D A Bullough,
- S Potter,
- M H Fox,
- C Zhang,
- E K Metzner,
- and K M Mullane
Acadesine prevents oxidant-induced damage in the isolated guinea pig heart.
J Pharmacol Exp Ther August 1993 266:666-672
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- M A Dawson and
- J L Renfro
Interaction of structurally similar pesticides with organic anion transport by primary cultures of winter flounder renal proximal tubule.
J Pharmacol Exp Ther August 1993 266:673-677
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- A Szallasi,
- N A Lewin,
- and P M Blumberg
Vanilloid (capsaicin) receptor in the rat: positive cooperativity of resiniferatoxin binding and its modulation by reduction and oxidation.
J Pharmacol Exp Ther August 1993 266:678-683
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- S M Sorensen,
- J H Kehne,
- G M Fadayel,
- T M Humphreys,
- H J Ketteler,
- C K Sullivan,
- V L Taylor,
- and C J Schmidt
Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies.
J Pharmacol Exp Ther August 1993 266:684-691
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- B J Ebersole,
- C A Diglio,
- D W Kaufman,
- and K A Berg
5-Hydroxytryptamine1-like receptors linked to increases in intracellular calcium concentration and inhibition of cyclic AMP accumulation in cultured vascular smooth muscle cells derived from bovine basilar artery.
J Pharmacol Exp Ther August 1993 266:692-699
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- J A Schriefer and
- C J Molineaux
Modulatory effect of endopeptidase inhibitors on bradykinin-induced contraction of rat uterus.
J Pharmacol Exp Ther August 1993 266:700-706
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- L L Bennett, Jr,
- P W Allan,
- P E Noker,
- L M Rose,
- S Niwas,
- J A Montgomery,
- and M D Erion
Purine nucleoside phosphorylase inhibitors: biochemical and pharmacological studies with 9-benzyl-9-deazaguanine and related compounds.
J Pharmacol Exp Ther August 1993 266:707-714
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- D Wu,
- S V Otton,
- P Morrow,
- T Inaba,
- W Kalow,
- and E M Sellers
Human hepatic cytochrome P450 2D6-like activity in nonhuman primates: catalytic characterization in vitro.
J Pharmacol Exp Ther August 1993 266:715-719
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- A Köppen,
- J Klein,
- T Holler,
- and K Löffelholz
Synergistic effect of nicotinamide and choline administration on extracellular choline levels in the brain.
J Pharmacol Exp Ther August 1993 266:720-725
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- E Ongini,
- E Bonizzoni,
- N Ferri,
- S Milani,
- and M Trampus
Differential effects of dopamine D-1 and D-2 receptor antagonist antipsychotics on sleep-wake patterns in the rat.
J Pharmacol Exp Ther August 1993 266:726-731
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- D L Leatherman and
- J L Middlebrook
Effects of emetine on the specific association of T-2 toxin with mammalian cells.
J Pharmacol Exp Ther August 1993 266:732-740
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- D L Leatherman and
- J L Middlebrook
Effect of emetine on T-2 toxin-induced inhibition of protein synthesis in mammalian cells.
J Pharmacol Exp Ther August 1993 266:741-748
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- E Etemadzadeh
Cerebral catecholamine depletion in mice withdrawn from repeated morphine treatment and development of tolerance to the enhancing effect of morphine on noradrenaline depletion.
J Pharmacol Exp Ther August 1993 266:749-755
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- M J Picker,
- J Yarbrough,
- C E Hughes,
- M A Smith,
- D Morgan,
- and L A Dykstra
Agonist and antagonist effects of mixed action opioids in the pigeon drug discrimination procedure: influence of training dose, intrinsic efficacy and interanimal differences.
J Pharmacol Exp Ther August 1993 266:756-767
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- M A Wilson and
- R Biscardi
Divergent alterations in gamma-aminobutyric acid responses of male and ovariectomized rats after chronic benzodiazepine agonist exposure: analysis of gamma-aminobutyric acid-activated chloride influx.
J Pharmacol Exp Ther August 1993 266:768-773
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- M A Wilson
Divergent alterations in gamma-aminobutyric acid/benzodiazepine responses of male and ovariectomized rats after chronic benzodiazepine agonist exposure: electrophysiological analysis of substantia nigra pars reticulata neurons.
J Pharmacol Exp Ther August 1993 266:774-779
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- K E Vanover,
- M F Piercey,
- and W L Woolverton
Evaluation of the reinforcing and discriminative stimulus effects of cocaine in combination with (+)-AJ76 or clozapine.
J Pharmacol Exp Ther August 1993 266:780-789
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- S I Harik,
- N J Riachi,
- M A Hritz,
- M S Berridge,
- and L M Sayre
Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies.
J Pharmacol Exp Ther August 1993 266:790-795
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- P S Puttfarcken,
- J S Handen,
- D T Montgomery,
- J T Coyle,
- and L L Werling
N-acetyl-aspartylglutamate modulation of N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat hippocampal slices.
J Pharmacol Exp Ther August 1993 266:796-803
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- N K Mello,
- Z Sarnyai,
- J H Mendelson,
- J M Drieze,
- and M Kelly
Acute effects of cocaine on anterior pituitary hormones in male and female rhesus monkeys.
J Pharmacol Exp Ther August 1993 266:804-811
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- F R Capaz,
- C Ruffié,
- J Lefort,
- S Manzini,
- B B Vargaftig,
- and M Pretolani
Effect of active sensitization on the bronchopulmonary responses to tachykinins in the guinea pig. Modulation by peptidase inhibitors.
J Pharmacol Exp Ther August 1993 266:812-819
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- P E Stewart and
- D L Hammond
Evidence for delta opioid receptor subtypes in rat spinal cord: studies with intrathecal naltriben, cyclic[D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin.
J Pharmacol Exp Ther August 1993 266:820-828
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- D G Lang,
- C M Wang,
- and B R Cooper
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells.
J Pharmacol Exp Ther August 1993 266:829-835
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- Q Li,
- M S Brownfield,
- G Battaglia,
- T M Cabrera,
- A D Levy,
- P A Rittenhouse,
- and L D van de Kar
Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (+-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI).
J Pharmacol Exp Ther August 1993 266:836-844
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- Q Xiaotao and
- S D Hall
Modulation of enantioselective metabolism and inversion of ibuprofen by xenobiotics in isolated rat hepatocytes.
J Pharmacol Exp Ther August 1993 266:845-851
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- S D Bologna,
- W L Hasler,
- and C Owyang
Down-regulation of motilin receptors on rabbit colon myocytes by chronic oral erythromycin.
J Pharmacol Exp Ther August 1993 266:852-856
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- M DeLegge,
- K S Murthy,
- J R Grider,
- and G M Makhlouf
Characterization of distinct receptors for the peptidyl leukotrienes LTC4 and LTD4/LTE4 coupled to the same signaling pathway in isolated gastric muscle cells.
J Pharmacol Exp Ther August 1993 266:857-863
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- H M Vargas,
- D Cunningham,
- L Zhou,
- H B Hartman,
- and A J Gorman
Cardiovascular effects of chloroethylclonidine, an irreversible alpha 1B-adrenoceptor antagonist, in the unanesthetized rat: a pharmacological analysis in vivo and in vitro.
J Pharmacol Exp Ther August 1993 266:864-871
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- A A Seymour,
- M M Asaad,
- V M Lanoce,
- K M Langenbacher,
- S A Fennell,
- and W L Rogers
Systemic hemodynamics, renal function and hormonal levels during inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in conscious dogs with pacing-induced heart failure.
J Pharmacol Exp Ther August 1993 266:872-883
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- M M Adamantidis,
- P Kerram,
- J F Caron,
- and B A Dupuis
Droperidol exerts dual effects on repolarization and induces early afterdepolarizations and triggered activity in rabbit Purkinje fibers.
J Pharmacol Exp Ther August 1993 266:884-893
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- L L Howell
Comparative effects of caffeine and selective phosphodiesterase inhibitors on respiration and behavior in rhesus monkeys.
J Pharmacol Exp Ther August 1993 266:894-903
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- D R Abernethy,
- I W Wainer,
- J A Longstreth,
- and N S Andrawis
Stereoselective verapamil disposition and dynamics in aging during racemic verapamil administration.
J Pharmacol Exp Ther August 1993 266:904-911
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- Z F Gu,
- W J Rossowski,
- D H Coy,
- T K Pradhan,
- and R T Jensen
Chimeric galanin analogs that function as antagonists in the CNS are full agonists in gastrointestinal smooth muscle.
J Pharmacol Exp Ther August 1993 266:912-918
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- B Stein,
- A Drögemüller,
- A Mülsch,
- W Schmitz,
- and H Scholz
Ca(++)-dependent constitutive nitric oxide synthase is not involved in the cyclic GMP-increasing effects of carbachol in ventricular cardiomyocytes.
J Pharmacol Exp Ther August 1993 266:919-925
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- P J Horan,
- B R de Costa,
- K Rice,
- R C Haaseth,
- V J Hruby,
- and F Porreca
Differential antagonism of bremazocine- and U69,593-induced antinociception by quadazocine: further functional evidence of opioid kappa receptor multiplicity in the mouse.
J Pharmacol Exp Ther August 1993 266:926-933
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- K E Barke and
- L B Hough
Simultaneous measurement of opiate-induced histamine release in the periaqueductal gray and opiate antinociception: an in vivo microdialysis study.
J Pharmacol Exp Ther August 1993 266:934-942
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- M L Cohen,
- M P Johnson,
- K W Schenck,
- A Susemichel,
- D B Wainscott,
- D W Robertson,
- and D L Nelson
DOI and alpha-methylserotonin: comparative vascular and nonvascular smooth muscle effects and central 5-hydroxytryptamine2 receptor affinities.
J Pharmacol Exp Ther August 1993 266:943-949
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- S W Watts and
- M L Cohen
Time-dependent improvement in guinea pig tracheal contractility: modification by cyclooxygenase inhibitors.
J Pharmacol Exp Ther August 1993 266:950-957
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- R D Verschoyle,
- C R Wolf,
- and D Dinsdale
Cytochrome P450 2B isoenzymes are responsible for the pulmonary bioactivation and toxicity of butylated hydroxytoluene, O,O,S-trimethylphosphorothioate and methylcyclopentadienyl manganese tricarbonyl.
J Pharmacol Exp Ther August 1993 266:958-963
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- J C Stevens and
- S A Wrighton
Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450.
J Pharmacol Exp Ther August 1993 266:964-971
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- C Bartel,
- C Wirtz,
- E Brändle,
- and J Greven
Interaction of thiazide and loop diuretics with the basolateral para-aminohippurate transport system in isolated S2 segments of rabbit kidney proximal tubules.
J Pharmacol Exp Ther August 1993 266:972-977
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- X Xu,
- T D Tsai,
- and K S Lee
A specific activator of the ATP-inhibited K+ channels in guinea pig ventricular cells.
J Pharmacol Exp Ther August 1993 266:978-984
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- R M Eisenberg
DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.
J Pharmacol Exp Ther August 1993 266:985-991
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- K C Chang,
- S Y Chung,
- W S Chong,
- J S Suh,
- S H Kim,
- H K Noh,
- B W Seong,
- H J Ko,
- and K W Chun
Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats.
J Pharmacol Exp Ther August 1993 266:992-1000
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- A M Gillis,
- H J Duff,
- L B Mitchell,
- and D G Wyse
Myocardial uptake and pharmacodynamics of procainamide in patients with coronary heart disease and sustained ventricular tachyarrhythmias.
J Pharmacol Exp Ther August 1993 266:1001-1006
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- P J Bushnell,
- C N Pope,
- and S Padilla
Behavioral and neurochemical effects of acute chlorpyrifos in rats: tolerance to prolonged inhibition of cholinesterase.
J Pharmacol Exp Ther August 1993 266:1007-1017
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- P Giusti,
- I Ducić,
- G Puia,
- R Arban,
- A Walser,
- A Guidotti,
- and E Costa
Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.
J Pharmacol Exp Ther August 1993 266:1018-1028
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- D E Brenneman,
- S W Page,
- M Schultzberg,
- F S Thomas,
- P Zelazowski,
- P Burnet,
- R Avidor,
- and E M Sternberg
A decomposition product of a contaminant implicated in L-tryptophan eosinophilia myalgia syndrome affects spinal cord neuronal cell death and survival through stereospecific, maturation and partly interleukin-1-dependent mechanisms.
J Pharmacol Exp Ther August 1993 266:1029-1035
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- J M Hanesworth,
- M F Sardinia,
- L T Krebs,
- K L Hall,
- and J W Harding
Elucidation of a specific binding site for angiotensin II(3-8), angiotensin IV, in mammalian heart membranes.
J Pharmacol Exp Ther August 1993 266:1036-1042
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- C J Mussap and
- E Burcher
Characterization and autoradiographic localization of tachykinin receptors in rat gastric fundus.
J Pharmacol Exp Ther August 1993 266:1043-1053
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- G J Christ,
- P R Brink,
- W Zhao,
- J Moss,
- C M Gondré,
- C Roy,
- and D C Spray
Gap junctions modulate tissue contractility and alpha 1 adrenergic agonist efficacy in isolated rat aorta.
J Pharmacol Exp Ther August 1993 266:1054-1065
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- J F Bowyer,
- B Gough,
- H W Broening,
- G D Newport,
- and L Schmued
Fluoro-gold and pentamidine inhibit the in vitro and in vivo release of dopamine in the striatum of rat.
J Pharmacol Exp Ther August 1993 266:1066-1074
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- F J White,
- X T Hu,
- and D J Henry
Electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies.
J Pharmacol Exp Ther August 1993 266:1075-1084
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- A A Nanji,
- S M Sadrzadeh,
- U Khettry,
- P Thomas,
- and T Yamanaka
Protective effects of a novel quinone derivative, (2E)-3-[5-(2,3 dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propanoic acid on experimental alcoholic liver injury.
J Pharmacol Exp Ther August 1993 266:1085-1090
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- E Ragazzi,
- A Chinellato,
- L Pandolfo,
- G Froldi,
- L Caparrotta,
- M Prosdocimi,
- G Aliev,
- and G Fassina
Atherosclerosis-related remodeling of aortic relaxation to purines in the Watanabe heritable hyperlipidemic rabbit.
J Pharmacol Exp Ther August 1993 266:1091-1096
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- G A Ricaurte,
- A L Markowska,
- G L Wenk,
- G Hatzidimitriou,
- J Wlos,
- and D S Olton
3,4-Methylenedioxymethamphetamine, serotonin and memory.
J Pharmacol Exp Ther August 1993 266:1097-1105
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- A W Thurston, Jr,
- S G Rhee,
- and S D Shukla
Role of guanine nucleotide-binding protein and tyrosine kinase in platelet-activating factor activation of phospholipase C in A431 cells: proposal for dual mechanisms.
J Pharmacol Exp Ther August 1993 266:1106-1112
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- C Nebigil and
- K U Malik
Alpha adrenergic receptor subtypes involved in prostaglandin synthesis are coupled to Ca++ channels through a pertussis toxin-sensitive guanine nucleotide-binding protein.
J Pharmacol Exp Ther August 1993 266:1113-1124
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- R P Carlson,
- D A Hartman,
- L A Tomchek,
- T L Walter,
- J R Lugay,
- W Calhoun,
- S N Sehgal,
- and J Y Chang
Rapamycin, a potential disease-modifying antiarthritic drug.
J Pharmacol Exp Ther August 1993 266:1125-1138
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- P Piguet and
- R A North
Opioid actions at mu and delta receptors in the rat dentate gyrus in vitro.
J Pharmacol Exp Ther August 1993 266:1139-1149
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November 2009, 331 (2)

Effects of the selective sigma receptor ligand, 6-[6-(4-hydroxypiperidinyl)hexyloxy]-3-methylflavone (NPC 16377), on behavioral and toxic effects of cocaine.

Role of neuropeptides in acetylcholine-induced edema in isolated and perfused rabbit lungs.

Effect of protein binding on 4-methylumbelliferyl sulfate desulfation kinetics in perfused rat liver.

Inhibition of H+/organic cation antiport by carboxyl reagents in rabbit renal brush-border membrane vesicles.

Angiotensin II inhibits glomerular adenylate cyclase via the angiotensin II receptor subtype 1 (AT1).

The in vivo antiplatelet effects of thromboxane A2 synthase inhibitors are potentiated by simultaneous thromboxane A2/prostaglandin H2 receptor blockade.

Pharmacological differentiation of metabotropic glutamate receptors coupled to potentiation of cyclic adenosine monophosphate responses and phosphoinositide hydrolysis.

Apparent mediation of the stimulus properties of a low dose of quinpirole by dopaminergic autoreceptors.

RS 42358-197, a novel and potent 5-HT3 receptor antagonist, in vitro and in vivo.

Dermorphin analog Tyr-D-Arg2-Phe-sarcosine-induced opioid analgesia and respiratory stimulation: the role of mu 1-receptors?

Role of the hydrophobic face of amphipathic alpha-helical peptides in synthetic pulmonary surfactants.

Evidence that neuroleptics increase striatal acetylcholine release through stimulation of dopamine D1 receptors.

Effects of the putative polyamine antagonists diethylenetriamine and 1,10-diaminodecane on N-methyl-D-aspartic acid-stimulated [3H]norepinephrine release from rat hippocampal slices.

Transduction of a discriminative stimulus through a diazepam-insensitive gamma-aminobutyric acidA receptor.

In vitro potency, affinity and agonist efficacy of highly selective delta opioid receptor ligands.

Discriminative stimulus properties of cocaine in relation to dopamine D2 receptor function in rats.

Further biological activities of the novel choline analogs selenonium choline and acetylselenonium choline.

Role of NMDA and non-NMDA receptors in the nucleus tractus solitarius in the depressant effect of ethanol on baroreflexes.

Selective potentiation by an A1 adenosine receptor enhancer of the negative dromotropic action of adenosine in the guinea pig heart.

Potency of 5-hydroxytryptamine1a agonists to inhibit adenylyl cyclase activity is a function of affinity for the "low-affinity" state of [3H]8-hydroxy-N,N-dipropylaminotetralin ([3H]8-OH-DPAT) binding.

Effect of some products of protein catabolism on the endothelium-dependent and -independent relaxation of rabbit thoracic aorta rings.

Inhibition of neurotransmitter release from enteric nerve endings by 2-[p-(carboxyethyl)-phenethylamino]-5'-N-ethylcarboxamido-adenosine (CGS-21680) and related adenosine analogs: lack of simple competition by antagonists.

Alterations in vascular structure and function after short-term losartan treatment in spontaneously hypertensive rats.

Ontogenic differences in the inhibition of gastric acid secretion by epidermal growth factor.

4-morpholinecarboximidine-N-1-adamantyl-N'-cyclohexylhydrochloride (U-37883A): pharmacological characterization of a novel antagonist of vascular ATP-sensitive K+ channel openers.

Acadesine prevents oxidant-induced damage in the isolated guinea pig heart.

Interaction of structurally similar pesticides with organic anion transport by primary cultures of winter flounder renal proximal tubule.

Vanilloid (capsaicin) receptor in the rat: positive cooperativity of resiniferatoxin binding and its modulation by reduction and oxidation.

Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies.

5-Hydroxytryptamine1-like receptors linked to increases in intracellular calcium concentration and inhibition of cyclic AMP accumulation in cultured vascular smooth muscle cells derived from bovine basilar artery.

Modulatory effect of endopeptidase inhibitors on bradykinin-induced contraction of rat uterus.

Purine nucleoside phosphorylase inhibitors: biochemical and pharmacological studies with 9-benzyl-9-deazaguanine and related compounds.

Human hepatic cytochrome P450 2D6-like activity in nonhuman primates: catalytic characterization in vitro.

Synergistic effect of nicotinamide and choline administration on extracellular choline levels in the brain.

Differential effects of dopamine D-1 and D-2 receptor antagonist antipsychotics on sleep-wake patterns in the rat.

Effects of emetine on the specific association of T-2 toxin with mammalian cells.

Effect of emetine on T-2 toxin-induced inhibition of protein synthesis in mammalian cells.

Cerebral catecholamine depletion in mice withdrawn from repeated morphine treatment and development of tolerance to the enhancing effect of morphine on noradrenaline depletion.

Agonist and antagonist effects of mixed action opioids in the pigeon drug discrimination procedure: influence of training dose, intrinsic efficacy and interanimal differences.

Divergent alterations in gamma-aminobutyric acid responses of male and ovariectomized rats after chronic benzodiazepine agonist exposure: analysis of gamma-aminobutyric acid-activated chloride influx.

Divergent alterations in gamma-aminobutyric acid/benzodiazepine responses of male and ovariectomized rats after chronic benzodiazepine agonist exposure: electrophysiological analysis of substantia nigra pars reticulata neurons.

Evaluation of the reinforcing and discriminative stimulus effects of cocaine in combination with (+)-AJ76 or clozapine.

Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies.

N-acetyl-aspartylglutamate modulation of N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat hippocampal slices.

Acute effects of cocaine on anterior pituitary hormones in male and female rhesus monkeys.

Effect of active sensitization on the bronchopulmonary responses to tachykinins in the guinea pig. Modulation by peptidase inhibitors.

Evidence for delta opioid receptor subtypes in rat spinal cord: studies with intrathecal naltriben, cyclic[D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin.

Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells.

Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (+-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI).

Modulation of enantioselective metabolism and inversion of ibuprofen by xenobiotics in isolated rat hepatocytes.

Down-regulation of motilin receptors on rabbit colon myocytes by chronic oral erythromycin.

Characterization of distinct receptors for the peptidyl leukotrienes LTC4 and LTD4/LTE4 coupled to the same signaling pathway in isolated gastric muscle cells.

Cardiovascular effects of chloroethylclonidine, an irreversible alpha 1B-adrenoceptor antagonist, in the unanesthetized rat: a pharmacological analysis in vivo and in vitro.

Systemic hemodynamics, renal function and hormonal levels during inhibition of neutral endopeptidase 3.4.24.11 and angiotensin-converting enzyme in conscious dogs with pacing-induced heart failure.

Droperidol exerts dual effects on repolarization and induces early afterdepolarizations and triggered activity in rabbit Purkinje fibers.

Comparative effects of caffeine and selective phosphodiesterase inhibitors on respiration and behavior in rhesus monkeys.

Stereoselective verapamil disposition and dynamics in aging during racemic verapamil administration.

Chimeric galanin analogs that function as antagonists in the CNS are full agonists in gastrointestinal smooth muscle.

Ca(++)-dependent constitutive nitric oxide synthase is not involved in the cyclic GMP-increasing effects of carbachol in ventricular cardiomyocytes.

Differential antagonism of bremazocine- and U69,593-induced antinociception by quadazocine: further functional evidence of opioid kappa receptor multiplicity in the mouse.

Simultaneous measurement of opiate-induced histamine release in the periaqueductal gray and opiate antinociception: an in vivo microdialysis study.

DOI and alpha-methylserotonin: comparative vascular and nonvascular smooth muscle effects and central 5-hydroxytryptamine2 receptor affinities.

Time-dependent improvement in guinea pig tracheal contractility: modification by cyclooxygenase inhibitors.

Cytochrome P450 2B isoenzymes are responsible for the pulmonary bioactivation and toxicity of butylated hydroxytoluene, O,O,S-trimethylphosphorothioate and methylcyclopentadienyl manganese tricarbonyl.

Interaction of the enantiomers of fluoxetine and norfluoxetine with human liver cytochromes P450.

Interaction of thiazide and loop diuretics with the basolateral para-aminohippurate transport system in isolated S2 segments of rabbit kidney proximal tubules.

A specific activator of the ATP-inhibited K+ channels in guinea pig ventricular cells.

DAMGO stimulates the hypothalamo-pituitary-adrenal axis through a mu-2 opioid receptor.

Possible superoxide radical-induced alteration of vascular reactivity in aortas from streptozotocin-treated rats.

Myocardial uptake and pharmacodynamics of procainamide in patients with coronary heart disease and sustained ventricular tachyarrhythmias.

Behavioral and neurochemical effects of acute chlorpyrifos in rats: tolerance to prolonged inhibition of cholinesterase.

Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.

A decomposition product of a contaminant implicated in L-tryptophan eosinophilia myalgia syndrome affects spinal cord neuronal cell death and survival through stereospecific, maturation and partly interleukin-1-dependent mechanisms.

Elucidation of a specific binding site for angiotensin II(3-8), angiotensin IV, in mammalian heart membranes.

Characterization and autoradiographic localization of tachykinin receptors in rat gastric fundus.

Gap junctions modulate tissue contractility and alpha 1 adrenergic agonist efficacy in isolated rat aorta.

Fluoro-gold and pentamidine inhibit the in vitro and in vivo release of dopamine in the striatum of rat.

Electrophysiological effects of cocaine in the rat nucleus accumbens: microiontophoretic studies.

Protective effects of a novel quinone derivative, (2E)-3-[5-(2,3 dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2-propanoic acid on experimental alcoholic liver injury.