Table of Contents

May 1993; 265 (2)

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- P R Farina,
- A G Graham,
- C A Homon,
- E S Lazer,
- S E Hattox,
- P S Riska,
- R H Gundel,
- and C D Wegner
A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor.
J Pharmacol Exp Ther May 1993 265:483-489
- Abstract
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- M Kageyama,
- T Yanagisawa,
- and N Taira
Calcitonin gene-related peptide relaxes porcine coronary arteries via cyclic AMP-dependent mechanisms, but not activation of ATP-sensitive potassium channels.
J Pharmacol Exp Ther May 1993 265:490-497
- Abstract
- Full Text (PDF)
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- S Matsubara,
- R Matsubara,
- I Kusumi,
- T Koyama,
- and I Yamashita
Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo.
J Pharmacol Exp Ther May 1993 265:498-508
- Abstract
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- J A Nathanson
Identification of octopaminergic agonists with selectivity for octopamine receptor subtypes.
J Pharmacol Exp Ther May 1993 265:509-515
- Abstract
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- Y Uejima,
- M Kokubo,
- J Oshida,
- H Kawabata,
- Y Kato,
- and K Fujii
5-Methyl-4H-3,1-benzoxazin-4-one derivatives: specific inhibitors of human leukocyte elastase.
J Pharmacol Exp Ther May 1993 265:516-523
- Abstract
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- B E Pichoff,
- C F Uyehara,
- and K T Nakamura
Effect of calcium agonists, BAY K 8644 and CGP 28392, on guinea pig airway smooth muscle function during development.
J Pharmacol Exp Ther May 1993 265:524-528
- Abstract
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- H K Im,
- W B Im,
- and K Tsuzuki
Selective block of transient Ca channel current in mouse neuroblastoma cells by U-88779E.
J Pharmacol Exp Ther May 1993 265:529-535
- Abstract
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- D J Detweiler,
- J C Eisenach,
- C Tong,
- and C Jackson
A cholinergic interaction in alpha 2 adrenoceptor-mediated antinociception in sheep.
J Pharmacol Exp Ther May 1993 265:536-542
- Abstract
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- D M Dennis,
- J Shryock,
- and L Belardinelli
Correlation of (-)N6-phenylisopropyladenosine blood levels with cardiac responses in the anesthetized guinea pig.
J Pharmacol Exp Ther May 1993 265:543-550
- Abstract
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- E A Kalso,
- A F Sullivan,
- H J McQuay,
- A H Dickenson,
- and B P Roques
Cross-tolerance between mu opioid and alpha-2 adrenergic receptors, but not between mu and delta opioid receptors in the spinal cord of the rat.
J Pharmacol Exp Ther May 1993 265:551-558
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- G J Grover,
- S Dzwonczyk,
- P G Sleph,
- and C A Sargent
The ATP-sensitive potassium channel blocker glibenclamide (glyburide) does not abolish preconditioning in isolated ischemic rat hearts.
J Pharmacol Exp Ther May 1993 265:559-564
- Abstract
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- C Yurdaydin,
- Z Q Gu,
- G Nowak,
- C Fromm,
- A G Holt,
- and A S Basile
Benzodiazepine receptor ligands are elevated in an animal model of hepatic encephalopathy: relationship between brain concentration and severity of encephalopathy.
J Pharmacol Exp Ther May 1993 265:565-571
- Abstract
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- R Schreiber and
- J de Vry
Studies on the neuronal circuits involved in the discriminative stimulus effects of 5-hydroxytryptamine1A receptor agonists in the rat.
J Pharmacol Exp Ther May 1993 265:572-579
- Abstract
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- M O Urban and
- D J Smith
Role of neurotensin in the nucleus raphe magnus in opioid-induced antinociception from the periaqueductal gray.
J Pharmacol Exp Ther May 1993 265:580-586
- Abstract
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- C D Kurth,
- C Monitto,
- M L Albuquerque,
- P Feuer,
- E Anday,
- and L Shaw
Cocaine and its metabolites constrict cerebral arterioles in newborn pigs.
J Pharmacol Exp Ther May 1993 265:587-591
- Abstract
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- N E Goeders and
- J E Smith
Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens.
J Pharmacol Exp Ther May 1993 265:592-600
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- S S Hegde and
- D E Clarke
Characterization of angiotensin receptors mediating the neuromodulatory effects of angiotensin in the vas deferens of the rabbit.
J Pharmacol Exp Ther May 1993 265:601-608
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- C A Sargent,
- P G Sleph,
- S Dzwonczyk,
- M A Smith,
- D Normandin,
- M J Antonaccio,
- and G J Grover
Cardioprotection in ischemic rat hearts with the SH-containing angiotensin-converting enzyme inhibitor zofenopril: possible involvement of the ATP-sensitive potassium channel.
J Pharmacol Exp Ther May 1993 265:609-618
- Abstract
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- G C Gao and
- E T Wei
Xenopsin, neurotensin, neurotensin(8-13) and N-acetyl-neurotensin(8-13) inhibit vascular leakage in rats after tissue injury.
J Pharmacol Exp Ther May 1993 265:619-625
- Abstract
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- G D Nicol
The calcium channel antagonist, pimozide, blocks the cyclic GMP-activated current in rod photoreceptors.
J Pharmacol Exp Ther May 1993 265:626-632
- Abstract
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- S P Welch
Blockade of cannabinoid-induced antinociception by norbinaltorphimine, but not N,N-diallyl-tyrosine-Aib-phenylalanine-leucine, ICI 174,864 or naloxone in mice.
J Pharmacol Exp Ther May 1993 265:633-640
- Abstract
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- T Shirayama,
- K Matsumoto,
- and A J Pappano
Carbachol-induced sodium current in guinea pig ventricular myocytes is not regulated by guanine nucleotides.
J Pharmacol Exp Ther May 1993 265:641-648
- Abstract
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- J Auta,
- E Romeo,
- A Kozikowski,
- D Ma,
- E Costa,
- and A Guidotti
Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.
J Pharmacol Exp Ther May 1993 265:649-656
- Abstract
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- H M Sadeghi and
- D C Eikenburg
Is sympathetic neurotransmission in the rat mesentery modulated by prejunctional beta adrenoceptors?
J Pharmacol Exp Ther May 1993 265:657-663
- Abstract
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- N Jaiswal,
- E A Tallant,
- R K Jaiswal,
- D I Diz,
- and C M Ferrario
Differential regulation of prostaglandin synthesis by angiotensin peptides in porcine aortic smooth muscle cells: subtypes of angiotensin receptors involved.
J Pharmacol Exp Ther May 1993 265:664-673
- Abstract
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- C Szabó,
- J A Mitchell,
- S S Gross,
- C Thiemermann,
- and J R Vane
Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.
J Pharmacol Exp Ther May 1993 265:674-680
- Abstract
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- H Takahashi,
- H Ogata,
- K Kashiwada,
- M Ohira,
- and K Someya
Dosing rate-dependent relationship between propranolol plasma concentration and beta-blockade.
J Pharmacol Exp Ther May 1993 265:681-689
- Abstract
- Full Text (PDF)
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- J B Schwartz,
- I F Troconiz,
- D Verotta,
- S Liu,
- and H Capili
Aging effects on stereoselective pharmacokinetics and pharmacodynamics of verapamil.
J Pharmacol Exp Ther May 1993 265:690-698
- Abstract
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- L A Merkel,
- L M Rivera,
- D J Colussi,
- M H Perrone,
- G J Smits,
- and B F Cox
In vitro and in vivo characterization of an A1-selective adenosine agonist, RG14202.
J Pharmacol Exp Ther May 1993 265:699-706
- Abstract
- Full Text (PDF)
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- S Hjorth and
- T Sharp
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.
J Pharmacol Exp Ther May 1993 265:707-712
- Abstract
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- M Parlani,
- B Conte,
- and S Manzini
Nonadrenergic, noncholinergic inhibitory control of the rat external urethral sphincter: involvement of nitric oxide.
J Pharmacol Exp Ther May 1993 265:713-719
- Abstract
- Full Text (PDF)
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- J J Lynch, Jr,
- A A Wallace,
- L H Van der Gaag,
- E P Baskin,
- C M Bear,
- J R Gehret,
- T Kothstein,
- R F Stupienski,
- S D Appleby,
- and M C Sanguinetti
Cardiac electrophysiologic and antiarrhythmic actions of 3,4-dihydro-1'-[2-(benzofurazan-5-yl) ethyl]-6-methanesulfonamidospiro [(2H)-1-benzopyran-2,4'-piperidin]-4-one HCl (L-691,121), a novel class III agent.
J Pharmacol Exp Ther May 1993 265:720-730
- Abstract
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- S L Bramer,
- J L Au,
- and M G Wientjes
Gastrointestinal and hepatic first-pass elimination of 2',3'-dideoxyinosine in rats.
J Pharmacol Exp Ther May 1993 265:731-738
- Abstract
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- S Prisco,
- A Cagnotto,
- D Talone,
- A De Blasi,
- T Mennini,
- and E Esposito
Tertatolol, a new beta-blocker, is a serotonin (5-hydroxytryptamine1A) receptor antagonist in rat brain.
J Pharmacol Exp Ther May 1993 265:739-744
- Abstract
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- Y Noda,
- S Kurumiya,
- Y Miura,
- and M Oka
Comparative study of 2-(4-ethyl-1-piperazinyl)-4-(fluorophenyl)-5,6,7,8,9, 10-hexahydrocycloocta[b]pyridine (AD-5423) and haloperidol for their pharmacological activities related to antipsychotic efficacy and/or adverse side-effects.
J Pharmacol Exp Ther May 1993 265:745-751
- Abstract
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- Y Nagakura,
- M Kadowaki,
- K Tokoro,
- M Tomoi,
- J Mori,
- and M Kohsaka
Pharmacological characterization of FK1052, a dihydropyridoindole derivative, as a new serotonin 3 and 4 dual receptor antagonist.
J Pharmacol Exp Ther May 1993 265:752-758
- Abstract
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- W B Xiao,
- A Nordberg,
- and X Zhang
Effect of in vivo microdialysis of 1,2,3,4-tetrahydro-9-aminoacridine (THA) on the extracellular concentration of acetylcholine in the striatum of anesthetized rats.
J Pharmacol Exp Ther May 1993 265:759-764
- Abstract
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- G Bonanno and
- M Raiteri
gamma-Aminobutyric acid (GABA) autoreceptors in rat cerebral cortex and spinal cord represent pharmacologically distinct subtypes of the GABAB receptor.
J Pharmacol Exp Ther May 1993 265:765-770
- Abstract
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- D M Lovinger and
- Q Zhou
Trichloroethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in nodose ganglion neurons from the adult rat.
J Pharmacol Exp Ther May 1993 265:771-776
- Abstract
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- E T Iwamoto and
- L Marion
Adrenergic, serotonergic and cholinergic components of nicotinic antinociception in rats.
J Pharmacol Exp Ther May 1993 265:777-789
- Abstract
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- Z Han,
- D Chatterjee,
- and J H Wyche
Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parental 8-Cl-cyclic AMP.
J Pharmacol Exp Ther May 1993 265:790-794
- Abstract
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- L A Burns,
- J A McCay,
- R Brown,
- and A E Munson
Arsenic in the sera of gallium arsenide-exposed mice inhibits bacterial growth and increases host resistance.
J Pharmacol Exp Ther May 1993 265:795-800
- Abstract
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- Y Furukawa,
- S Takayama,
- S Sawaki,
- Y Inoue,
- and S Chiba
A bradycardic agent, UL-FS 49, increases atrial force and decreases ventricular force in isolated, perfused heart preparations of dogs.
J Pharmacol Exp Ther May 1993 265:801-806
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- M P Owen
Functional characterization of alpha adrenoceptors on rabbit intrarenal arteries in vitro.
J Pharmacol Exp Ther May 1993 265:807-812
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- I Elayan,
- J W Gibb,
- G R Hanson,
- H K Lim,
- R L Foltz,
- and M Johnson
Short-term effects of 2,4,5-trihydroxyamphetamine, 2,4,5-trihydroxymethamphetamine and 3,4-dihydroxymethamphetamine on central tryptophan hydroxylase activity.
J Pharmacol Exp Ther May 1993 265:813-818
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- Y Abe,
- Y Kitada,
- and A Narimatsu
Effect of MCI-154, a cardiotonic agent, on regional contractile function and myocardial oxygen consumption in the presence and absence of coronary artery stenosis in dogs.
J Pharmacol Exp Ther May 1993 265:819-825
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- C Cazaubon,
- J Gougat,
- F Bousquet,
- P Guiraudou,
- R Gayraud,
- C Lacour,
- A Roccon,
- G Galindo,
- G Barthelemy,
- and B Gautret
Pharmacological characterization of SR 47436, a new nonpeptide AT1 subtype angiotensin II receptor antagonist.
J Pharmacol Exp Ther May 1993 265:826-834
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- P Sánchez-Blázquez and
- J Garzón
N-acetyl beta-endorphin-(1-31) and substance P regulate the supraspinal antinociception mediated by mu opioid and alpha-2 adrenoceptors but not by delta opioid receptors in the mouse.
J Pharmacol Exp Ther May 1993 265:835-843
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- M Yoshiyama,
- J R Roppolo,
- and W C de Groat
Effects of MK-801 on the micturition reflex in the rat--possible sites of action.
J Pharmacol Exp Ther May 1993 265:844-850
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- K Matsuno,
- K Matsunaga,
- T Senda,
- and S Mita
Increase in extracellular acetylcholine level by sigma ligands in rat frontal cortex.
J Pharmacol Exp Ther May 1993 265:851-859
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- R S Garcha,
- P S Sever,
- and A D Hughes
The action of amlodipine on human subcutaneous resistance arteries studied in vitro.
J Pharmacol Exp Ther May 1993 265:860-865
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- E W Karbon,
- M E Abreu,
- R H Erickson,
- C Kaiser,
- K J Natalie, Jr,
- D B Clissold,
- S Borosky,
- M Bailey,
- L A Martin,
- and M J Pontecorvo
NPC 16377, a potent and selective sigma-ligand. I. Receptor binding, neurochemical and neuroendocrine profile.
J Pharmacol Exp Ther May 1993 265:866-875
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- D B Clissold,
- M J Pontecorvo,
- B E Jones,
- M E Abreu,
- E W Karbon,
- R H Erickson,
- K J Natalie, Jr,
- S Borosky,
- T Hartman,
- and R S Mansbach
NPC 16377, a potent and selective sigma-ligand. II. Behavioral and neuroprotective profile.
J Pharmacol Exp Ther May 1993 265:876-886
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- M P Owen
Similarities and differences in the postjunctional role for neuropeptide Y in sympathetic vasomotor control of large vs. small arteries of rabbit renal and ear vasculature.
J Pharmacol Exp Ther May 1993 265:887-895
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- P J Horan,
- K D Wild,
- A Misicka,
- A Lipkowski,
- R C Haaseth,
- V J Hruby,
- S J Weber,
- T P Davis,
- H I Yamamura,
- and F Porreca
Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity.
J Pharmacol Exp Ther May 1993 265:896-902
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- S Foucart,
- D Bleakman,
- V P Bindokas,
- and R J Miller
Neuropeptide Y and pancreatic polypeptide reduce calcium currents in acutely dissociated neurons from adult rat superior cervical ganglia.
J Pharmacol Exp Ther May 1993 265:903-909
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- P T Brackley and
- P N Usherwood
Are chimeric kainate/N-methyl-D-aspartate receptors expressed in Xenopus oocytes from mammalian and amphibian RNA?
J Pharmacol Exp Ther May 1993 265:910-919
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- V N Mutafova-Yambolieva,
- K M Venkova,
- and L S Lasova
Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.
J Pharmacol Exp Ther May 1993 265:920-926
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- B Ault and
- L M Hildebrand
Activation of nociceptive reflexes by peripheral kainate receptors.
J Pharmacol Exp Ther May 1993 265:927-932
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- M A Clark,
- S J Humphrey,
- M P Smith,
- and J H Ludens
Unique natriuretic properties of the ATP-sensitive K(+)-channel blocker glyburide in conscious rats.
J Pharmacol Exp Ther May 1993 265:933-937
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- M I Walton and
- P Workman
Pharmacokinetics and bioreductive metabolism of the novel benzotriazine di-N-oxide hypoxic cell cytotoxin tirapazamine (WIN 59075; SR 4233; NSC 130181) in mice.
J Pharmacol Exp Ther May 1993 265:938-947
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- J D Kaunitz,
- Y Nishizaki,
- K Kaneko,
- and P H Guth
Effect of orogastric nicotine on rat gastric mucosal gel thickness, surface cell viability and intracellular pH.
J Pharmacol Exp Ther May 1993 265:948-954
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- E L Lecluyse,
- S C Sutton,
- and J A Fix
In vitro effects of long-chain acylcarnitines on the permeability, transepithelial electrical resistance and morphology of rat colonic mucosa.
J Pharmacol Exp Ther May 1993 265:955-962
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- J M Ackerman,
- P A Johansen,
- D Clark,
- and F J White
Electrophysiological effects of putative autoreceptor-selective dopamine agonists on A10 dopamine neurons.
J Pharmacol Exp Ther May 1993 265:963-970
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- L L Howell
Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys.
J Pharmacol Exp Ther May 1993 265:971-978
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- B H Shapiro,
- N A Pampori,
- P A Ram,
- and D J Waxman
Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate.
J Pharmacol Exp Ther May 1993 265:979-984
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- A Y Valeyev,
- J L Barker,
- R A Cruciani,
- G D Lange,
- V V Smallwood,
- and L C Mahan
Characterization of the gamma-aminobutyric acidA receptor-channel complex composed of alpha 1 beta 2 and alpha 1 beta 3 subunits from rat brain.
J Pharmacol Exp Ther May 1993 265:985-991
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- J L Renfro,
- M A Brown,
- S L Parker,
- and L E Hightower
Relationship of thermal and chemical tolerance to transepithelial transport by cultured flounder renal epithelium.
J Pharmacol Exp Ther May 1993 265:992-1000
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- H E Criswell,
- K B Johnson,
- R A Mueller,
- and G R Breese
Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats.
J Pharmacol Exp Ther May 1993 265:1001-1010
- Abstract
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- A N Lopatin and
- C G Nichols
2,3-Butanedione monoxime (BDM) inhibition of delayed rectifier DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes.
J Pharmacol Exp Ther May 1993 265:1011-1016
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- Y Tamura,
- Y Sato,
- T Yokota,
- A Akaike,
- M Sasa,
- and S Takaori
Ifenprodil prevents glutamate cytotoxicity via polyamine modulatory sites of N-methyl-D-aspartate receptors in cultured cortical neurons.
J Pharmacol Exp Ther May 1993 265:1017-1025
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- Y T Shen and
- S F Vatner
Effects of a K+ATP channel opener, lemakalim, on systemic, coronary and regional vascular dynamics in conscious dogs: comparison with nifedipine, adenosine, nitroglycerin and acetylcholine.
J Pharmacol Exp Ther May 1993 265:1026-1037
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Current Issue

November 2009, 331 (2)

A prodrug of a 2,6-disubstituted 4-(2-arylethenyl)phenol is a selective and orally active 5-lipoxygenase inhibitor.

Calcitonin gene-related peptide relaxes porcine coronary arteries via cyclic AMP-dependent mechanisms, but not activation of ATP-sensitive potassium channels.

Dopamine D1, D2 and serotonin2 receptor occupation by typical and atypical antipsychotic drugs in vivo.

Identification of octopaminergic agonists with selectivity for octopamine receptor subtypes.

5-Methyl-4H-3,1-benzoxazin-4-one derivatives: specific inhibitors of human leukocyte elastase.

Effect of calcium agonists, BAY K 8644 and CGP 28392, on guinea pig airway smooth muscle function during development.

Selective block of transient Ca channel current in mouse neuroblastoma cells by U-88779E.

A cholinergic interaction in alpha 2 adrenoceptor-mediated antinociception in sheep.

Correlation of (-)N6-phenylisopropyladenosine blood levels with cardiac responses in the anesthetized guinea pig.

Cross-tolerance between mu opioid and alpha-2 adrenergic receptors, but not between mu and delta opioid receptors in the spinal cord of the rat.

The ATP-sensitive potassium channel blocker glibenclamide (glyburide) does not abolish preconditioning in isolated ischemic rat hearts.

Benzodiazepine receptor ligands are elevated in an animal model of hepatic encephalopathy: relationship between brain concentration and severity of encephalopathy.

Studies on the neuronal circuits involved in the discriminative stimulus effects of 5-hydroxytryptamine1A receptor agonists in the rat.

Role of neurotensin in the nucleus raphe magnus in opioid-induced antinociception from the periaqueductal gray.

Cocaine and its metabolites constrict cerebral arterioles in newborn pigs.

Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens.

Characterization of angiotensin receptors mediating the neuromodulatory effects of angiotensin in the vas deferens of the rabbit.

Cardioprotection in ischemic rat hearts with the SH-containing angiotensin-converting enzyme inhibitor zofenopril: possible involvement of the ATP-sensitive potassium channel.

Xenopsin, neurotensin, neurotensin(8-13) and N-acetyl-neurotensin(8-13) inhibit vascular leakage in rats after tissue injury.

The calcium channel antagonist, pimozide, blocks the cyclic GMP-activated current in rod photoreceptors.

Blockade of cannabinoid-induced antinociception by norbinaltorphimine, but not N,N-diallyl-tyrosine-Aib-phenylalanine-leucine, ICI 174,864 or naloxone in mice.

Carbachol-induced sodium current in guinea pig ventricular myocytes is not regulated by guanine nucleotides.

Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.

Is sympathetic neurotransmission in the rat mesentery modulated by prejunctional beta adrenoceptors?

Differential regulation of prostaglandin synthesis by angiotensin peptides in porcine aortic smooth muscle cells: subtypes of angiotensin receptors involved.

Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.

Dosing rate-dependent relationship between propranolol plasma concentration and beta-blockade.

Aging effects on stereoselective pharmacokinetics and pharmacodynamics of verapamil.

In vitro and in vivo characterization of an A1-selective adenosine agonist, RG14202.

In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.

Nonadrenergic, noncholinergic inhibitory control of the rat external urethral sphincter: involvement of nitric oxide.

Cardiac electrophysiologic and antiarrhythmic actions of 3,4-dihydro-1'-[2-(benzofurazan-5-yl) ethyl]-6-methanesulfonamidospiro [(2H)-1-benzopyran-2,4'-piperidin]-4-one HCl (L-691,121), a novel class III agent.

Gastrointestinal and hepatic first-pass elimination of 2',3'-dideoxyinosine in rats.

Tertatolol, a new beta-blocker, is a serotonin (5-hydroxytryptamine1A) receptor antagonist in rat brain.

Comparative study of 2-(4-ethyl-1-piperazinyl)-4-(fluorophenyl)-5,6,7,8,9, 10-hexahydrocycloocta[b]pyridine (AD-5423) and haloperidol for their pharmacological activities related to antipsychotic efficacy and/or adverse side-effects.

Pharmacological characterization of FK1052, a dihydropyridoindole derivative, as a new serotonin 3 and 4 dual receptor antagonist.

Effect of in vivo microdialysis of 1,2,3,4-tetrahydro-9-aminoacridine (THA) on the extracellular concentration of acetylcholine in the striatum of anesthetized rats.

gamma-Aminobutyric acid (GABA) autoreceptors in rat cerebral cortex and spinal cord represent pharmacologically distinct subtypes of the GABAB receptor.

Trichloroethanol potentiation of 5-hydroxytryptamine3 receptor-mediated ion current in nodose ganglion neurons from the adult rat.

Adrenergic, serotonergic and cholinergic components of nicotinic antinociception in rats.

Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parental 8-Cl-cyclic AMP.

Arsenic in the sera of gallium arsenide-exposed mice inhibits bacterial growth and increases host resistance.

A bradycardic agent, UL-FS 49, increases atrial force and decreases ventricular force in isolated, perfused heart preparations of dogs.

Functional characterization of alpha adrenoceptors on rabbit intrarenal arteries in vitro.

Short-term effects of 2,4,5-trihydroxyamphetamine, 2,4,5-trihydroxymethamphetamine and 3,4-dihydroxymethamphetamine on central tryptophan hydroxylase activity.

Effect of MCI-154, a cardiotonic agent, on regional contractile function and myocardial oxygen consumption in the presence and absence of coronary artery stenosis in dogs.

Pharmacological characterization of SR 47436, a new nonpeptide AT1 subtype angiotensin II receptor antagonist.

N-acetyl beta-endorphin-(1-31) and substance P regulate the supraspinal antinociception mediated by mu opioid and alpha-2 adrenoceptors but not by delta opioid receptors in the mouse.

Effects of MK-801 on the micturition reflex in the rat--possible sites of action.

Increase in extracellular acetylcholine level by sigma ligands in rat frontal cortex.

The action of amlodipine on human subcutaneous resistance arteries studied in vitro.

NPC 16377, a potent and selective sigma-ligand. I. Receptor binding, neurochemical and neuroendocrine profile.

NPC 16377, a potent and selective sigma-ligand. II. Behavioral and neuroprotective profile.

Similarities and differences in the postjunctional role for neuropeptide Y in sympathetic vasomotor control of large vs. small arteries of rabbit renal and ear vasculature.

Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity.

Neuropeptide Y and pancreatic polypeptide reduce calcium currents in acutely dissociated neurons from adult rat superior cervical ganglia.

Are chimeric kainate/N-methyl-D-aspartate receptors expressed in Xenopus oocytes from mammalian and amphibian RNA?

Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.

Activation of nociceptive reflexes by peripheral kainate receptors.

Unique natriuretic properties of the ATP-sensitive K(+)-channel blocker glyburide in conscious rats.

Pharmacokinetics and bioreductive metabolism of the novel benzotriazine di-N-oxide hypoxic cell cytotoxin tirapazamine (WIN 59075; SR 4233; NSC 130181) in mice.

Effect of orogastric nicotine on rat gastric mucosal gel thickness, surface cell viability and intracellular pH.

In vitro effects of long-chain acylcarnitines on the permeability, transepithelial electrical resistance and morphology of rat colonic mucosa.

Electrophysiological effects of putative autoreceptor-selective dopamine agonists on A10 dopamine neurons.

Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxia in rhesus monkeys.

Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate.

Characterization of the gamma-aminobutyric acidA receptor-channel complex composed of alpha 1 beta 2 and alpha 1 beta 3 subunits from rat brain.

Relationship of thermal and chemical tolerance to transepithelial transport by cultured flounder renal epithelium.

Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats.

2,3-Butanedione monoxime (BDM) inhibition of delayed rectifier DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes.

Ifenprodil prevents glutamate cytotoxicity via polyamine modulatory sites of N-methyl-D-aspartate receptors in cultured cortical neurons.

Effects of a K+ATP channel opener, lemakalim, on systemic, coronary and regional vascular dynamics in conscious dogs: comparison with nifedipine, adenosine, nitroglycerin and acetylcholine.

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