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Table of Contents
April 1993; 265 (1)
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S Yasar
,
C W Schindler
,
E B Thorndike
,
I Szelenyi
,
and
S R Goldberg
Evaluation of the stereoisomers of deprenyl for amphetamine-like discriminative stimulus effects in rats.
J Pharmacol Exp Ther
April 1993
265
:
1
-
6
Abstract
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P Blier
,
A Lista
,
and
C De Montigny
Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone.
J Pharmacol Exp Ther
April 1993
265
:
7
-
15
Abstract
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P Blier
,
A Lista
,
and
C De Montigny
Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: II. Effect of pertussis and cholera toxins.
J Pharmacol Exp Ther
April 1993
265
:
16
-
23
Abstract
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R P Simon
,
J Chen
,
and
S H Graham
GM1 ganglioside treatment of focal ischemia: a dose-response and microdialysis study.
J Pharmacol Exp Ther
April 1993
265
:
24
-
29
Abstract
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R D Bukoski
,
J Bo
,
H Xue
,
and
K Bian
Antiproliferative and endothelium-dependent vasodilator properties of 1,3-dihydro-3-p-chlorophenyl-7-hydroxy-6-methyl-furo-(3,4c) pyridine hydrochloride (cicletanine).
J Pharmacol Exp Ther
April 1993
265
:
30
-
35
Abstract
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G Piedimonte
,
J I Hoffman
,
W K Husseini
,
C Bertrand
,
R M Snider
,
M C Desai
,
G Petersson
,
and
J A Nadel
Neurogenic vasodilation in the rat nasal mucosa involves neurokinin1 tachykinin receptors.
J Pharmacol Exp Ther
April 1993
265
:
36
-
40
Abstract
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M Okamoto
,
L J Viskatis
,
G de la Roza
,
and
J C Vidal
Induction of tolerance to crotoxin in mice.
J Pharmacol Exp Ther
April 1993
265
:
41
-
46
Abstract
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R J Lamb
and
R R Griffiths
Behavioral effects of pentobarbital, lorazepam, ethanol and chlorpromazine substitution in pentobarbital-dependent baboons.
J Pharmacol Exp Ther
April 1993
265
:
47
-
52
Abstract
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T S Shippenberg
,
R Bals-Kubik
,
and
A Herz
Examination of the neurochemical substrates mediating the motivational effects of opioids: role of the mesolimbic dopamine system and D-1 vs. D-2 dopamine receptors.
J Pharmacol Exp Ther
April 1993
265
:
53
-
59
Abstract
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P P Sokol
,
K L Longenecker
,
D L Kachel
,
and
W J Martin, 2nd
Mechanism of putrescine transport in human pulmonary artery endothelial cells.
J Pharmacol Exp Ther
April 1993
265
:
60
-
66
Abstract
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K Raynor
,
I Lucki
,
and
T Reisine
Somatostatin receptors in the nucleus accumbens selectively mediate the stimulatory effect of somatostatin on locomotor activity in rats.
J Pharmacol Exp Ther
April 1993
265
:
67
-
73
Abstract
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J C Sill
,
S Eskuri
,
R Nelson
,
J Tarara
,
and
R A Van Dyke
The volatile anesthetic isoflurane attenuates Ca++ mobilization in cultured vascular smooth muscle cells.
J Pharmacol Exp Ther
April 1993
265
:
74
-
80
Abstract
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D O Freier
and
B A Fuchs
Morphine-induced alterations in thymocyte subpopulations of B6C3F1 mice.
J Pharmacol Exp Ther
April 1993
265
:
81
-
88
Abstract
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S C Baraban
,
R L Stornetta
,
and
P G Guyenet
Respiratory control of sympathetic nerve activity during naloxone-precipitated morphine withdrawal in rats.
J Pharmacol Exp Ther
April 1993
265
:
89
-
95
Abstract
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M Million
,
J Fioramonti
,
S Gicquel
,
J M Zajac
,
and
L Bueno
Comparative action of Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 analogs on intestinal motility and nociception in rats.
J Pharmacol Exp Ther
April 1993
265
:
96
-
102
Abstract
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A Colzi
,
F D'Agostini
,
A M Cesura
,
E Borroni
,
and
M Da Prada
Monoamine oxidase-A inhibitors and dopamine metabolism in rat caudatus: evidence that an increased cytosolic level of dopamine displaces reversible monoamine oxidase-A inhibitors in vivo.
J Pharmacol Exp Ther
April 1993
265
:
103
-
111
Abstract
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Y X Wang
,
C I Poon
,
and
C C Pang
In vitro and ex vivo inhibitory effects of L- and D-enantiomers of NG-nitro-arginine on endothelium-dependent relaxation of rat aorta.
J Pharmacol Exp Ther
April 1993
265
:
112
-
119
Abstract
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T J Hudzik
and
G R Wenger
Effects of drugs of abuse and cholinergic agents on delayed matching-to-sample responding in the squirrel monkey.
J Pharmacol Exp Ther
April 1993
265
:
120
-
127
Abstract
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S L Cruz
and
J E Villarreal
Acute opioid dependence in the cardiovascular system of the spinal rat.
J Pharmacol Exp Ther
April 1993
265
:
128
-
133
Abstract
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D R Kapusta
,
J C Obih
,
and
G F Dibona
Central mu opioid receptor-mediated changes in renal function in conscious rats.
J Pharmacol Exp Ther
April 1993
265
:
134
-
143
Abstract
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L A Burns
and
A E Munson
Reversal of gallium arsenide-induced suppression of the antibody-forming cell response by vehicle supernatants. I. Pharmacokinetics after in vitro and in vivo exposure.
J Pharmacol Exp Ther
April 1993
265
:
144
-
149
Abstract
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L A Burns
and
A E Munson
Reversal of gallium arsenide-induced suppression of the antibody-forming cell response by vehicle supernatants. II. Nature and identification of reversing factors.
J Pharmacol Exp Ther
April 1993
265
:
150
-
158
Abstract
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A A Larson
and
X Sun
Modulation of kainic acid-induced activity in the mouse spinal cord by the amino terminus of substance P: sensitivity to opioid antagonists.
J Pharmacol Exp Ther
April 1993
265
:
159
-
165
Abstract
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C G Pick
,
R J Nejat
,
and
G W Pasternak
Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains.
J Pharmacol Exp Ther
April 1993
265
:
166
-
171
Abstract
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R E Tessel
,
D W Miller
,
G A Misse
,
X Dong
,
and
M B Doughty
Characterization of vascular postsynaptic neuropeptide Y receptor function and regulation. 1. NPY-induced constriction in isolated rat femoral artery rings is mediated by both Y1 and Y2 receptors: evidence from benextramine protection studies.
J Pharmacol Exp Ther
April 1993
265
:
172
-
177
Abstract
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L A Burns
and
A E Munson
Gallium arsenide selectively inhibits T cell proliferation and alters expression of CD25 (IL-2R/p55).
J Pharmacol Exp Ther
April 1993
265
:
178
-
186
Abstract
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T C Major
,
R W Overhiser
,
D G Taylor, Jr
,
and
R L Panek
Effects of quinapril, a new angiotensin-converting enzyme inhibitor, on vasoconstrictor activity in the isolated, perfused mesenteric vasculature of hypertensive rats.
J Pharmacol Exp Ther
April 1993
265
:
187
-
193
Abstract
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S B Backman
,
M Bachoo
,
and
C Polosa
Mechanism of the bradycardia produced in the cat by the anticholinesterase neostigmine.
J Pharmacol Exp Ther
April 1993
265
:
194
-
200
Abstract
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P L Martin
,
A A Potts
,
A M Sykes
,
and
D G McKenna
(+-)-N6-endonorbornan-2-yl-9-methyladenine (N-0861) and its enantiomers: selective antagonists of A1-adenosine receptors in guinea pig isolated atria.
J Pharmacol Exp Ther
April 1993
265
:
201
-
206
Abstract
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B S Neal-Beliveau
,
J N Joyce
,
and
I Lucki
Serotonergic involvement in haloperidol-induced catalepsy.
J Pharmacol Exp Ther
April 1993
265
:
207
-
217
Abstract
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D R Compton
,
K C Rice
,
B R De Costa
,
R K Razdan
,
L S Melvin
,
M R Johnson
,
and
B R Martin
Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.
J Pharmacol Exp Ther
April 1993
265
:
218
-
226
Abstract
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R J Barrett
,
J M May
,
P L Martin
,
and
J R Miller
In vitro and in vivo pharmacological characterization of N6-cyclopentyl-9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist.
J Pharmacol Exp Ther
April 1993
265
:
227
-
236
Abstract
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C Carpéné
,
J Galitzky
,
P Collon
,
F Esclapez
,
M Dauzats
,
and
M Lafontan
Desensitization of beta-1 and beta-2, but not beta-3, adrenoceptor-mediated lipolytic responses of adipocytes after long-term norepinephrine infusion.
J Pharmacol Exp Ther
April 1993
265
:
237
-
247
Abstract
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P L Martin
,
M Ueeda
,
and
R A Olsson
2-Phenylethoxy-9-methyladenine: an adenosine receptor antagonist that discriminates between A2 adenosine receptors in the aorta and the coronary vessels from the guinea pig.
J Pharmacol Exp Ther
April 1993
265
:
248
-
253
Abstract
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J E Zadina
,
S L Chang
,
L J Ge
,
and
A J Kastin
Mu opiate receptor down-regulation by morphine and up-regulation by naloxone in SH-SY5Y human neuroblastoma cells.
J Pharmacol Exp Ther
April 1993
265
:
254
-
262
Abstract
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Y X Wang
and
C C Pang
Functional integrity of the central and sympathetic nervous systems is a prerequisite for pressor and tachycardic effects of diphenyleneiodonium, a novel inhibitor of nitric oxide synthase.
J Pharmacol Exp Ther
April 1993
265
:
263
-
272
Abstract
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G Sprakties
,
H J Macherey
,
and
K U Petersen
Secretin and somatostatin as modulators of electrolyte transport in guinea pig gallbladder epithelium.
J Pharmacol Exp Ther
April 1993
265
:
273
-
280
Abstract
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J M Mathews
and
J R Bend
N-aralkyl derivatives of 1-aminobenzotriazole as potent isozyme-selective mechanism-based inhibitors of rabbit pulmonary cytochrome P450 in vivo.
J Pharmacol Exp Ther
April 1993
265
:
281
-
285
Abstract
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S Parvini
,
S R Hamann
,
and
W R Martin
Pharmacologic characteristics of a medullary hyperalgesic center.
J Pharmacol Exp Ther
April 1993
265
:
286
-
293
Abstract
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R J Lukas
Expression of ganglia-type nicotinic acetylcholine receptors and nicotinic ligand binding sites by cells of the IMR-32 human neuroblastoma clonal line.
J Pharmacol Exp Ther
April 1993
265
:
294
-
302
Abstract
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J L Goudreau
,
J Manzanares
,
K J Lookingland
,
and
K E Moore
5HT2 receptors mediate the effects of stress on the activity of periventricular hypophysial dopaminergic neurons and the secretion of alpha-melanocyte-stimulating hormone.
J Pharmacol Exp Ther
April 1993
265
:
303
-
307
Abstract
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L Wang
,
M R Lucey
,
A M Fras
,
E J Wilson
,
and
J Del Valle
Epidermal growth factor and transforming growth factor-alpha directly inhibit parietal cell function through a similar mechanism.
J Pharmacol Exp Ther
April 1993
265
:
308
-
313
Abstract
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B C Yoburn
,
B Billings
,
and
A Duttaroy
Opioid receptor regulation in mice.
J Pharmacol Exp Ther
April 1993
265
:
314
-
320
Abstract
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C A Yiamouyiannis
,
B J Martin
,
and
J B Watkins, 3rd
Chronic physical activity alters hepatobiliary excretory function in rats.
J Pharmacol Exp Ther
April 1993
265
:
321
-
327
Abstract
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T Imai
,
A Fukuhara
,
I Ueda
,
and
M Otagiri
An evaluation of an anti-inflammatory-histamine H2 antagonist drug complex on gastric erosions in the rat.
J Pharmacol Exp Ther
April 1993
265
:
328
-
333
Abstract
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P C Churchill
and
V R Ellis
Pharmacological characterization of the renovascular P2 purinergic receptors.
J Pharmacol Exp Ther
April 1993
265
:
334
-
338
Abstract
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F Y Chen
and
T J Lee
Role of nitric oxide in neurogenic vasodilation of porcine cerebral artery.
J Pharmacol Exp Ther
April 1993
265
:
339
-
345
Abstract
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R H Schwinger
,
M Böhm
,
C Schulz
,
U Schmidt
,
U Schmidt
,
B Schmid
,
H Dienemann
,
B Reichart
,
and
E Erdmann
Cardiac inotropic as well as coronary and pulmonary artery actions of epinine in human isolated tissues.
J Pharmacol Exp Ther
April 1993
265
:
346
-
357
Abstract
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J J Pancrazio
,
M J Frazer
,
and
C Lynch, 3rd
Barbiturate anesthetics depress the resting K+ conductance of myocardium.
J Pharmacol Exp Ther
April 1993
265
:
358
-
365
Abstract
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A Berson
,
C Wolf
,
C Chachaty
,
C Fisch
,
D Fau
,
D Eugene
,
J Loeper
,
J C Gauthier
,
P Beaune
,
and
D Pompon
Metabolic activation of the nitroaromatic antiandrogen flutamide by rat and human cytochromes P-450, including forms belonging to the 3A and 1A subfamilies.
J Pharmacol Exp Ther
April 1993
265
:
366
-
372
Abstract
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S Benloucif
,
M J Keegan
,
and
M P Galloway
Serotonin-facilitated dopamine release in vivo: pharmacological characterization.
J Pharmacol Exp Ther
April 1993
265
:
373
-
377
Abstract
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A A Alhaider
and
G L Wilcox
Differential roles of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptor subtypes in modulating spinal nociceptive transmission in mice.
J Pharmacol Exp Ther
April 1993
265
:
378
-
385
Abstract
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R D Verschoyle
,
D Dinsdale
,
and
C R Wolf
Inhibition and induction of cytochrome P450 isoenzymes in rat lung.
J Pharmacol Exp Ther
April 1993
265
:
386
-
391
Abstract
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R Imberti
,
A L Nieminen
,
B Herman
,
and
J J Lemasters
Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.
J Pharmacol Exp Ther
April 1993
265
:
392
-
400
Abstract
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W Tassaneeyakul
,
D J Birkett
,
M E Veronese
,
M E McManus
,
R H Tukey
,
L C Quattrochi
,
H V Gelboin
,
and
J O Miners
Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.
J Pharmacol Exp Ther
April 1993
265
:
401
-
407
Abstract
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S F Rosebrough
Plasma stability and pharmacokinetics of radiolabeled deferoxamine-biotin derivatives.
J Pharmacol Exp Ther
April 1993
265
:
408
-
415
Abstract
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P Tagari
,
A Becker
,
C Brideau
,
R Frenette
,
V Sadl
,
E Thomas
,
P Vickers
,
and
A Ford-Hutchinson
Leukotriene generation and metabolism in dogs: inhibition of biosynthesis by MK-0591.
J Pharmacol Exp Ther
April 1993
265
:
416
-
425
Abstract
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A M Lin
,
R K Freund
,
and
M R Palmer
Sensitization of gamma-aminobutyric acid-induced depressions of cerebellar Purkinje neurons to the potentiative effects of ethanol by beta adrenergic mechanisms in rat brain.
J Pharmacol Exp Ther
April 1993
265
:
426
-
432
Abstract
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J G Contrera
,
S W Mcleskey
,
I Holopainen
,
J Xu
,
and
W J Wojcik
Muscarinic m2 receptors in cerebellar granule cell cultures from rat: mechanism of short-term desensitization.
J Pharmacol Exp Ther
April 1993
265
:
433
-
440
Abstract
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P Longone
,
I Mocchetti
,
M A Riva
,
and
W J Wojcik
Characterization of a decrease in muscarinic m2 mRNA in cerebellar granule cells by carbachol.
J Pharmacol Exp Ther
April 1993
265
:
441
-
446
Abstract
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G W Dorn, 2nd
and
M W Becker
Thromboxane A2 stimulated signal transduction in vascular smooth muscle.
J Pharmacol Exp Ther
April 1993
265
:
447
-
456
Abstract
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C W Benjamin
,
A H Lin
,
J Morris
,
D G Wishka
,
and
R R Gorman
2-Aminochromones block human platelet aggregation by inhibiting cyclic AMP-dependent phosphodiesterase leading to reduced platelet phospholipase C activity.
J Pharmacol Exp Ther
April 1993
265
:
457
-
462
Abstract
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T Gemba
,
M Ninomiya
,
K Matsunaga
,
and
M Ueda
Effects of a novel calcium antagonist, S-(+)-methyl-4,7-dihydro-3-isobutyl-6- methyl-4-(3-nitrophenyl)thieno[2,3-b]pyridine-5-carboxylate (S-312-d), on ischemic amino acid release and neuronal injury in stroke-prone spontaneously hypertensive rats.
J Pharmacol Exp Ther
April 1993
265
:
463
-
467
Abstract
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Z K Krowicki
and
P J Hornby
Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway.
J Pharmacol Exp Ther
April 1993
265
:
468
-
476
Abstract
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M Murray
,
E Cantrill
,
and
G C Farrell
Induction of cytochrome P450 2B1 in rat liver by the aromatase inhibitor aminoglutethimide.
J Pharmacol Exp Ther
April 1993
265
:
477
-
481
Abstract
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