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Table of Contents
January 1993; 264 (1)
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E Donato di Paola
,
B Cusack
,
M Yamada
,
and
E Richelson
Desensitization and down-regulation of neurotensin receptors in murine neuroblastoma clone N1E-115 by [D-Lys8] neurotensin(8-13).
J Pharmacol Exp Ther
January 1993
264
:
1
-
5
Abstract
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G L DeGraaf
,
D T Pals
,
S J Couch
,
and
J A Lawson
Hormonal and cardiovascular effects of losartan (DuP753), an angiotensin receptor antagonist, in nonhuman primates.
J Pharmacol Exp Ther
January 1993
264
:
6
-
10
Abstract
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M J Miller
,
H Sadowska-Krowicka
,
S Chotinaruemol
,
J L Kakkis
,
and
D A Clark
Amelioration of chronic ileitis by nitric oxide synthase inhibition.
J Pharmacol Exp Ther
January 1993
264
:
11
-
16
Abstract
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R Patacchini
,
L Quartara
,
P Rovero
,
C Goso
,
and
C A Maggi
Role of C-terminal amidation on the biological activity of neurokinin A derivatives with agonist and antagonist properties.
J Pharmacol Exp Ther
January 1993
264
:
17
-
21
Abstract
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E Reuveny
,
D A Twombly
,
and
T Narahashi
Chlordiazepoxide block of two types of calcium channels in neuroblastoma cells.
J Pharmacol Exp Ther
January 1993
264
:
22
-
28
Abstract
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T S King
,
M S Canez
,
S Gaskill
,
M A Javors
,
and
R S Schenken
Chronic cocaine disruption of estrous cyclicity in the rat: dose-dependent effects.
J Pharmacol Exp Ther
January 1993
264
:
29
-
34
Abstract
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M Ohta
,
J Nelson
,
D Nelson
,
M D Meglasson
,
and
M Erecińska
Effect of Ca++ channel blockers on energy level and stimulated insulin secretion in isolated rat islets of Langerhans.
J Pharmacol Exp Ther
January 1993
264
:
35
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40
Abstract
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I Y Hwang
and
A A Elfarra
Detection and mechanisms of formation of S-(6-purinyl)glutathione and 6-mercaptopurine in rats given 6-chloropurine.
J Pharmacol Exp Ther
January 1993
264
:
41
-
46
Abstract
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T J Cicero
,
B Nock
,
and
L O'Connor
Naloxone does not reverse the inhibitory effect of morphine on luteinizing hormone secretion in prepubescent male rats.
J Pharmacol Exp Ther
January 1993
264
:
47
-
53
Abstract
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K Yokotani
and
Y Osumi
Cholinergic M2 muscarinic receptor-mediated inhibition of endogenous noradrenaline release from the isolated vascularly perfused rat stomach.
J Pharmacol Exp Ther
January 1993
264
:
54
-
60
Abstract
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T R Traynor
,
D R Brown
,
and
S M O'Grady
Effects of inflammatory mediators on electrolyte transport across the porcine distal colon epithelium.
J Pharmacol Exp Ther
January 1993
264
:
61
-
66
Abstract
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G R Thomas
,
H Thibodeaux
,
W F Bennett
,
C J Refino
,
J M Badillo
,
C J Errett
,
and
J A Zivin
Optimized thrombolysis of cerebral clots with tissue-type plasminogen activator in a rabbit model of embolic stroke.
J Pharmacol Exp Ther
January 1993
264
:
67
-
73
Abstract
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M McKinney
,
J H Miller
,
and
P J Aagaard
Pharmacological characterization of the rat hippocampal muscarinic autoreceptor.
J Pharmacol Exp Ther
January 1993
264
:
74
-
78
Abstract
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W J de Ridder
and
J A Schuurkes
Cisapride and 5-hydroxytryptamine enhance motility in the canine antrum via separate pathways, not involving 5-hydroxytryptamine1,2,3,4 receptors.
J Pharmacol Exp Ther
January 1993
264
:
79
-
88
Abstract
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T Yasumori
,
L Chen
,
K Nagata
,
Y Yamazoe
,
and
R Kato
Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A).
J Pharmacol Exp Ther
January 1993
264
:
89
-
94
Abstract
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K Bervoets
,
J M Rivet
,
and
M J Millan
5-HT1A receptors and the tail-flick response. IV. Spinally localized 5-HT1A receptors postsynaptic to serotoninergic neurones mediate spontaneous tail-flicks in the rat.
J Pharmacol Exp Ther
January 1993
264
:
95
-
104
Abstract
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S Homma
,
E Kusano
,
S Takeda
,
N Murayama
,
Y Asano
,
and
T P Dousa
Both beta-1 and beta-2 adrenoceptors are coupled to the cyclic AMP system in connecting tubules of rabbit nephron.
J Pharmacol Exp Ther
January 1993
264
:
105
-
109
Abstract
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K Raynor
and
T Reisine
Subtypes of somatostatin receptors are expressed in the anterior pituitary cell line GH3.
J Pharmacol Exp Ther
January 1993
264
:
110
-
116
Abstract
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A Ogasawara
,
H Hisa
,
and
S Satoh
An intracellular calcium release inhibitor TMB-8 suppresses renal nerve stimulation-induced antinatriuresis in dogs.
J Pharmacol Exp Ther
January 1993
264
:
117
-
121
Abstract
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K Ichihara
,
T Nabeshima
,
and
T Kameyama
Dopaminergic agonists impair latent learning in mice: possible modulation by noradrenergic function.
J Pharmacol Exp Ther
January 1993
264
:
122
-
128
Abstract
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G Balasubramaniam
,
H S Lee
,
and
S C Mah
Differences in the acute and chronic antihypertensive mechanism of action of ketanserin in spontaneously hypertensive rats.
J Pharmacol Exp Ther
January 1993
264
:
129
-
134
Abstract
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G D Lopaschuk
,
R B Wambolt
,
and
R L Barr
An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemic hearts.
J Pharmacol Exp Ther
January 1993
264
:
135
-
144
Abstract
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E R Butelman
,
C P France
,
and
J H Woods
Apparent pA2 analysis on the respiratory depressant effects of alfentanil, etonitazene, ethylketocyclazocine (EKC) and Mr2033 in rhesus monkeys.
J Pharmacol Exp Ther
January 1993
264
:
145
-
151
Abstract
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S Ueki
,
M Seiki
,
T Yoneta
,
H Aita
,
K Chaki
,
Y Hori
,
H Morita
,
E Tagashira
,
and
Z Itoh
Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats.
J Pharmacol Exp Ther
January 1993
264
:
152
-
157
Abstract
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M Oka
,
Y Noda
,
Y Ochi
,
K Furukawa
,
T Une
,
S Kurumiya
,
K Hino
,
and
T Karasawa
Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties.
J Pharmacol Exp Ther
January 1993
264
:
158
-
165
Abstract
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Y Imamura
,
K Iwamoto
,
Y Yanachi
,
T Higuchi
,
and
M Otagiri
Postnatal development, sex-related difference and hormonal regulation of acetohexamide reductase activities in rat liver and kidney.
J Pharmacol Exp Ther
January 1993
264
:
166
-
171
Abstract
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P Ernsberger
,
T H Damon
,
L M Graff
,
S G Schäfer
,
and
M O Christen
Moxonidine, a centrally acting antihypertensive agent, is a selective ligand for I1-imidazoline sites.
J Pharmacol Exp Ther
January 1993
264
:
172
-
182
Abstract
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J L Katz
,
J W Griffiths
,
L G Sharpe
,
E B De Souza
,
and
J M Witkin
Cocaine tolerance and cross-tolerance.
J Pharmacol Exp Ther
January 1993
264
:
183
-
192
Abstract
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D J Cushing
and
M L Cohen
Serotonin-induced contraction in porcine coronary artery: use of ergolines to support vascular 5-hydroxytryptamine2-receptor heterogeneity.
J Pharmacol Exp Ther
January 1993
264
:
193
-
200
Abstract
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Y Shimamoto
,
H Shimamoto
,
C Y Kwan
,
and
E E Daniel
Rauwolscine induces contraction in the dog mesenteric artery precontracted with KCl and endothelin-1: mediation via 5-hydroxytryptamine1-like receptors.
J Pharmacol Exp Ther
January 1993
264
:
201
-
209
Abstract
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J S Fedan
,
J J Belt
,
L X Yuan
,
and
D G Frazer
Contractile effects of nucleotides in guinea pig isolated, perfused trachea: involvement of respiratory epithelium, prostanoids and Na+ and Cl- channels.
J Pharmacol Exp Ther
January 1993
264
:
210
-
216
Abstract
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J S Fedan
,
J J Belt
,
L X Yuan
,
and
D G Frazer
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine.
J Pharmacol Exp Ther
January 1993
264
:
217
-
220
Abstract
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E F Domino
and
J Sheng
N-methyl-D-aspartate receptor antagonist and dopamine D1 and D2 agonist interactions in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced hemiparkinsonian monkeys.
J Pharmacol Exp Ther
January 1993
264
:
221
-
225
Abstract
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S Fujita
,
S Umeda
,
Y Funae
,
S Imaoka
,
H Abe
,
R Ishida
,
T Adachi
,
M Masuda
,
A Kazusaka
,
and
T Suzuki
Regio- and stereoselective propranolol metabolism by 15 forms of purified cytochromes P-450 from rat liver.
J Pharmacol Exp Ther
January 1993
264
:
226
-
233
Abstract
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P Kostka
,
E Jang
,
E G Watson
,
J L Stewart
,
and
E E Daniel
Nitric oxide synthase in the autonomic nervous system of canine ileum.
J Pharmacol Exp Ther
January 1993
264
:
234
-
239
Abstract
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G W Gullikson
,
M A Virina
,
R F Loeffler
,
D C Yang
,
B Goldstin
,
S X Wang
,
C Moummi
,
D L Flynn
,
and
D L Zabrowski
SC-49518 enhances gastric emptying of solid and liquid meals and stimulates gastrointestinal motility in dogs by a 5-hydroxytryptamine4 receptor mechanism.
J Pharmacol Exp Ther
January 1993
264
:
240
-
248
Abstract
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M E Wolf
,
F J White
,
R Nassar
,
R J Brooderson
,
and
M R Khansa
Differential development of autoreceptor subsensitivity and enhanced dopamine release during amphetamine sensitization.
J Pharmacol Exp Ther
January 1993
264
:
249
-
255
Abstract
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J W Ferkany
,
G S Hamilton
,
R J Patch
,
Z Huang
,
S A Borosky
,
D L Bednar
,
B E Jones
,
R Zubrowski
,
J Willetts
,
and
E W Karbon
Pharmacological profile of NPC 17742 [2R,4R,5S-(2-amino-4,5-(1, 2-cyclohexyl)-7-phosphonoheptanoic acid)], a potent, selective and competitive N-methyl-D-aspartate receptor antagonist.
J Pharmacol Exp Ther
January 1993
264
:
256
-
264
Abstract
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M J Winn
,
N K Asante
,
and
D D Ku
Vasomotor responses of canine coronary arterial rings to NG-monomethyl-L-arginine and N omega nitro L-arginine methyl ester.
J Pharmacol Exp Ther
January 1993
264
:
265
-
270
Abstract
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S W Watts
and
M L Cohen
Further evidence that the guinea pig tracheal contractile serotonergic receptor is a 5-hydroxytryptamine2 receptor: use of 5-methyltryptamine and dipropyl-5-carboxamidotryptamine.
J Pharmacol Exp Ther
January 1993
264
:
271
-
275
Abstract
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N A Shahabi
and
B M Sharp
Activation of protein kinase C rapidly down-regulates naloxone-resistant receptors for beta-endorphin on U937 cells.
J Pharmacol Exp Ther
January 1993
264
:
276
-
281
Abstract
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R A Gonzales
,
L C Roper
,
and
S L Westbrook
Cholinergic modulation of N-methyl-D-aspartate-evoked [3H]norepinephrine release from rat cortical slices.
J Pharmacol Exp Ther
January 1993
264
:
282
-
288
Abstract
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K D Youngren
,
D A Daly
,
and
B Moghaddam
Distinct actions of endogenous excitatory amino acids on the outflow of dopamine in the nucleus accumbens.
J Pharmacol Exp Ther
January 1993
264
:
289
-
293
Abstract
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C J Heyser
,
R E Hampson
,
and
S A Deadwyler
Effects of delta-9-tetrahydrocannabinol on delayed match to sample performance in rats: alterations in short-term memory associated with changes in task specific firing of hippocampal cells.
J Pharmacol Exp Ther
January 1993
264
:
294
-
307
Abstract
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D J Pettibone
,
B V Clineschmidt
,
M T Kishel
,
E V Lis
,
D R Reiss
,
C J Woyden
,
B E Evans
,
R M Freidinger
,
D F Veber
,
and
M J Cook
Identification of an orally active, nonpeptidyl oxytocin antagonist.
J Pharmacol Exp Ther
January 1993
264
:
308
-
314
Abstract
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J M Gallo
,
A R Swagler
,
M Mehta
,
and
M Qian
Pharmacokinetic evaluation of drug interactions with anti-human immunodeficiency virus drugs. VI. Effect of the calcium channel blocker nimodipine on zidovudine kinetics in monkeys.
J Pharmacol Exp Ther
January 1993
264
:
315
-
320
Abstract
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K Kaechi
,
Y Furukawa
,
R Ikegami
,
N Nakamura
,
F Omae
,
Y Hashimoto
,
K Hayashi
,
and
S Furukawa
Pharmacological induction of physiologically active nerve growth factor in rat peripheral nervous system.
J Pharmacol Exp Ther
January 1993
264
:
321
-
326
Abstract
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Y Takano
and
T L Yaksh
Chronic spinal infusion of dexmedetomidine, ST-91 and clonidine: spinal alpha 2 adrenoceptor subtypes and intrinsic activity.
J Pharmacol Exp Ther
January 1993
264
:
327
-
335
Abstract
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P Hoffmann
,
I Heinroth-Hoffmann
,
and
M Toraason
Alterations by a thromboxane A2 analog (U46619) of calcium dynamics in isolated rat cardiomyocytes.
J Pharmacol Exp Ther
January 1993
264
:
336
-
344
Abstract
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P Nambi
,
M Pullen
,
M Jugus
,
and
M Gellai
Rat kidney endothelin receptors in ischemia-induced acute renal failure.
J Pharmacol Exp Ther
January 1993
264
:
345
-
348
Abstract
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B Nock
,
A L Giordano
,
B W Moore
,
and
T J Cicero
Properties of the putative epsilon opioid receptor: identification in rat, guinea pig, cow, pig and chicken brain.
J Pharmacol Exp Ther
January 1993
264
:
349
-
359
Abstract
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W K Bickel
,
A H Oliveto
,
J B Kamien
,
S T Higgins
,
and
J R Hughes
A novel-response procedure enhances the selectivity and sensitivity of a triazolam discrimination in humans.
J Pharmacol Exp Ther
January 1993
264
:
360
-
367
Abstract
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J M Thomas
and
B B Hoffman
Buprenorphine prevents and reverses the expression of chronic etorphine-induced sensitization of adenylyl cyclase in SK-N-SH human neuroblastoma cells.
J Pharmacol Exp Ther
January 1993
264
:
368
-
374
Abstract
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J J Galligan
Differential inhibition of cholinergic and noncholinergic neurogenic contractions by mu opioid and alpha-2 adrenergic agonists in guinea pig ileum.
J Pharmacol Exp Ther
January 1993
264
:
375
-
383
Abstract
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D M Hammerbeck
and
D R Brown
Neurally mediated actions of leukotrienes on ion transport in guinea pig distal colon.
J Pharmacol Exp Ther
January 1993
264
:
384
-
390
Abstract
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P Holzer
,
W Schluet
,
and
C A Maggi
Ascending enteric reflex contraction: roles of acetylcholine and tachykinins in relation to distension and propagation of excitation.
J Pharmacol Exp Ther
January 1993
264
:
391
-
396
Abstract
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T Hohlfeld
,
H Strobach
,
and
K Schrör
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury.
J Pharmacol Exp Ther
January 1993
264
:
397
-
405
Abstract
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P Soares-da-Silva
,
M H Fernandes
,
and
M Pestana
Studies on the role of sodium on the synthesis of dopamine in the rat kidney.
J Pharmacol Exp Ther
January 1993
264
:
406
-
414
Abstract
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J K Zubieta
and
K A Frey
Autoradiographic mapping of M3 muscarinic receptors in the rat brain.
J Pharmacol Exp Ther
January 1993
264
:
415
-
422
Abstract
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I Holopainen
and
W J Wojcik
A specific antisense oligodeoxynucleotide to mRNAs encoding receptors with seven transmembrane spanning regions decreases muscarinic m2 and gamma-aminobutyric acidB receptors in rat cerebellar granule cells.
J Pharmacol Exp Ther
January 1993
264
:
423
-
430
Abstract
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A Ricci
,
S Escaf
,
J A Vega
,
and
F Amenta
Autoradiographic localization of dopamine D1 receptors in the human kidney.
J Pharmacol Exp Ther
January 1993
264
:
431
-
437
Abstract
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T M Badger
,
M J Ronis
,
C K Lumpkin
,
C R Valentine
,
M Shahare
,
D Irby
,
J Huang
,
C Mercado
,
P Thomas
,
and
M Ingelman-Sundberg
Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat.
J Pharmacol Exp Ther
January 1993
264
:
438
-
447
Abstract
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C R Breese
,
A D'Costa
,
R L Ingram
,
J Lenham
,
and
W E Sonntag
Long-term suppression of insulin-like growth factor-1 in rats after in utero ethanol exposure: relationship to somatic growth.
J Pharmacol Exp Ther
January 1993
264
:
448
-
456
Abstract
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M D Maines
,
R D Mayer
,
J F Ewing
,
and
W K McCoubrey, Jr
Induction of kidney heme oxygenase-1 (HSP32) mRNA and protein by ischemia/reperfusion: possible role of heme as both promotor of tissue damage and regulator of HSP32.
J Pharmacol Exp Ther
January 1993
264
:
457
-
462
Abstract
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K Sunaga
,
D M Chuang
,
and
R Ishitani
Tetrahydroaminoacridine is neurotrophic and promotes the expression of muscarinic receptor-coupled phosphoinositide turnover in differentiating cerebellar granule cells.
J Pharmacol Exp Ther
January 1993
264
:
463
-
468
Abstract
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S Kamei
,
H Okada
,
Y Inoue
,
T Yoshioka
,
Y Ogawa
,
and
H Toguchi
Antitumor effects of angiogenesis inhibitor TNP-470 in rabbits bearing VX-2 carcinoma by arterial administration of microspheres and oil solution.
J Pharmacol Exp Ther
January 1993
264
:
469
-
474
Abstract
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C Jin
,
J O Miners
,
K J Lillywhite
,
and
P I Mackenzie
Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.
J Pharmacol Exp Ther
January 1993
264
:
475
-
479
Abstract
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K Rasmussen
,
J F Czachura
,
M E Stockton
,
and
J J Howbert
Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain dopamine neurons.
J Pharmacol Exp Ther
January 1993
264
:
480
-
488
Abstract
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R Bals-Kubik
,
A Ableitner
,
A Herz
,
and
T S Shippenberg
Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats.
J Pharmacol Exp Ther
January 1993
264
:
489
-
495
Abstract
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J Nagakawa
,
K Hirota
,
I Hishinuma
,
K Miyamoto
,
J Sonoda
,
T Yamanaka
,
K Katayama
,
and
I Yamatsu
Protective effect of E3330, a novel quinone derivative, in galactosamine-induced hepatitis in rats.
J Pharmacol Exp Ther
January 1993
264
:
496
-
500
Abstract
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S P Roux
,
T B Tschopp
,
H Kuhn
,
B Steiner
,
and
P Hadváry
Effects of heparin, aspirin and a synthetic platelet glycoprotein IIb-IIIa receptor antagonist (Ro 43-5054) on coronary artery reperfusion and reocclusion after thrombolysis with tissue-type plasminogen activator in the dog.
J Pharmacol Exp Ther
January 1993
264
:
501
-
508
Abstract
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G Petersson
,
E Bacci
,
D M McDonald
,
and
J A Nadel
Neurogenic plasma extravasation in the rat nasal mucosa is potentiated by peptidase inhibitors.
J Pharmacol Exp Ther
January 1993
264
:
509
-
514
Abstract
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ERRATUM
J Pharmacol Exp Ther
January 1993
264
:
514
Abstract
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January 1993; 264 (1)
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