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Table of Contents
December 1992; 263 (3)
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Y Yamaguchi
,
F J Fenoy
,
R J Roman
,
and
A Nasjletti
Angiotensin II influences the renal hemodynamic response to blockade of thromboxane A2 and prostaglandin H2 receptors.
J Pharmacol Exp Ther
December 1992
263
:
905
-
909
Abstract
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E H Gerstin, Jr
,
T Luong
,
and
F J Ehlert
Heparin, dextran and trypan blue allosterically modulate M2 muscarinic receptor binding properties and interfere with receptor-mediated inhibition of adenylate cyclase.
J Pharmacol Exp Ther
December 1992
263
:
910
-
917
Abstract
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K J Slavik
and
J E Szilagyi
Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors.
J Pharmacol Exp Ther
December 1992
263
:
918
-
927
Abstract
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T Li
,
K Croce
,
and
R J Winquist
Vasoconstrictor and vasodilator effects of serotonin in the isolated rabbit kidney.
J Pharmacol Exp Ther
December 1992
263
:
928
-
932
Abstract
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R M Burch
,
J R Connor
,
J M Bator
,
M Weitzberg
,
K Laemont
,
L Noronha-Blob
,
J P Sullivan
,
and
L R Steranka
NPC 15669 inhibits the reversed passive Arthus reaction in rats by blocking neutrophil recruitment.
J Pharmacol Exp Ther
December 1992
263
:
933
-
937
Abstract
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U Frei
,
R Schindler
,
C Matthies
,
and
K M Koch
Glomerular hemodynamics of the clipped kidney: effects of captopril and diltiazem.
J Pharmacol Exp Ther
December 1992
263
:
938
-
942
Abstract
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M Ohno
,
T Yamamoto
,
and
S Watanabe
Effects of intrahippocampal injections of N-methyl-D-aspartate receptor antagonists and scopolamine on working and reference memory assessed in rats by a three-panel runway task.
J Pharmacol Exp Ther
December 1992
263
:
943
-
950
Abstract
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K Kuratani
,
M Yamazaki
,
H Kodama
,
and
I Yamaguchi
Possible involvement of hyperinsulinemia and adrenergic activation in the pathogenesis of indomethacin-induced antral ulcers in nonfasted hamsters and refed rats.
J Pharmacol Exp Ther
December 1992
263
:
951
-
955
Abstract
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Y Suzuki
,
Y Matsumura
,
Y Egi
,
and
S Morimoto
Effects of Losartan, a nonpeptide angiotensin II receptor antagonist, on norepinephrine overflow and antidiuresis induced by stimulation of renal nerves in anesthetized dogs.
J Pharmacol Exp Ther
December 1992
263
:
956
-
963
Abstract
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R Kannan
,
J F Kuhlenkamp
,
M Ookhtens
,
and
N Kaplowitz
Transport of glutathione at blood-brain barrier of the rat: inhibition by glutathione analogs and age-dependence.
J Pharmacol Exp Ther
December 1992
263
:
964
-
970
Abstract
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T Fujita
,
M Nishikawa
,
C Tamaki
,
Y Takakura
,
M Hashida
,
and
H Sezaki
Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives.
J Pharmacol Exp Ther
December 1992
263
:
971
-
978
Abstract
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M Columbo
,
M Taglialatela
,
J A Warner
,
D W MacGlashan, Jr
,
T Yasumoto
,
L Annunziato
,
and
G Marone
Maitotoxin, a novel activator of mediator release from human basophils, induces large increases in cytosolic calcium resulting in histamine, but not leukotriene C4, release.
J Pharmacol Exp Ther
December 1992
263
:
979
-
986
Abstract
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C Nebigil
and
K U Malik
Comparison of signal transduction mechanisms of alpha-2C and alpha-1A adrenergic receptor-stimulated prostaglandin synthesis.
J Pharmacol Exp Ther
December 1992
263
:
987
-
996
Abstract
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R K Gordon
,
R R Gray
,
C B Reaves
,
D L Butler
,
and
P K Chiang
Induced release of acetylcholine from guinea pig ileum longitudinal muscle-myenteric plexus by anatoxin-a.
J Pharmacol Exp Ther
December 1992
263
:
997
-
1002
Abstract
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C Madhu
,
Z Gregus
,
and
C D Klaassen
Marked interanimal differences in susceptibility of Sprague-Dawley rats to diquat-induced oxidative stress in the liver: correlation with hepatic uptake of diquat.
J Pharmacol Exp Ther
December 1992
263
:
1003
-
1008
Abstract
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W T Jackson
,
R J Boyd
,
L L Froelich
,
B E Mallett
,
and
D M Gapinski
Specific inhibition of leukotriene B4-induced neutrophil activation by LY223982.
J Pharmacol Exp Ther
December 1992
263
:
1009
-
1014
Abstract
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M D Swedberg
,
H E Shannon
,
B Nickel
,
and
S R Goldberg
D-16949 (anpirtoline): a novel serotonergic (5-HT1B) psychotherapeutic agent assessed by its discriminative effects in the rat.
J Pharmacol Exp Ther
December 1992
263
:
1015
-
1022
Abstract
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M R Cernadas
,
A López-Farré
,
A Riesco
,
M J Gallego
,
G Espinosa
,
E Digiuni
,
L Hernando
,
S Casado
,
and
C Caramelo
Renal and systemic effects of aminoacids administered separately: comparison between L-arginine and non-nitric oxide donor aminoacids.
J Pharmacol Exp Ther
December 1992
263
:
1023
-
1029
Abstract
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R B Raffa
,
K D Wild
,
H I Mosberg
,
and
F Porreca
Thermodynamic analysis of the temperature dependence of the dissociation constant of naloxone at opioid delta receptors in the mouse isolated vas deferens.
J Pharmacol Exp Ther
December 1992
263
:
1030
-
1035
Abstract
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H Watanabe
,
S Ohdo
,
M Ishikawa
,
and
N Ogawa
Effects of social isolation on pentobarbital activity in mice: relationship to racemate levels and enantiomer levels in brain.
J Pharmacol Exp Ther
December 1992
263
:
1036
-
1045
Abstract
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C Correa-Sales
,
C Nacif-Coelho
,
K Reid
,
and
M Maze
Inhibition of adenylate cyclase in the locus coeruleus mediates the hypnotic response to an alpha 2 agonist in the rat.
J Pharmacol Exp Ther
December 1992
263
:
1046
-
1049
Abstract
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S E Ishikawa
,
K Okada
,
and
T Saito
Modulation by intracellular calcium pool of arginine vasopressin-induced cellular cyclic AMP production in rat renal papillary collecting tubule cells in culture.
J Pharmacol Exp Ther
December 1992
263
:
1050
-
1055
Abstract
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P J Little
,
M L Adams
,
and
T J Cicero
Effects of alcohol on the hypothalamic-pituitary-gonadal axis in the developing male rat.
J Pharmacol Exp Ther
December 1992
263
:
1056
-
1061
Abstract
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J E Porter
,
F J Dowd
,
and
P W Abel
Atypical alpha-1 adrenergic receptors on the rat parotid gland acinar cell.
J Pharmacol Exp Ther
December 1992
263
:
1062
-
1067
Abstract
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T S Gaginella
,
M B Grisham
,
D B Thomas
,
R Walsh
,
and
C Moummi
Oxidant-evoked release of acetylcholine from enteric neurons of the rat colon.
J Pharmacol Exp Ther
December 1992
263
:
1068
-
1073
Abstract
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G J Grover
,
P G Sleph
,
M Fox
,
and
N C Trippodo
Role of endothelin-1 and big endothelin-1 in modulating coronary vascular tone, contractile function and severity of ischemia in rat hearts.
J Pharmacol Exp Ther
December 1992
263
:
1074
-
1082
Abstract
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G Tavernier
,
J Galitzky
,
A Bousquet-Melou
,
J L Montastruc
,
and
M Berlan
The positive chronotropic effect induced by BRL 37344 and CGP 12177, two beta-3 adrenergic agonists, does not involve cardiac beta adrenoceptors but baroreflex mechanisms.
J Pharmacol Exp Ther
December 1992
263
:
1083
-
1090
Abstract
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C D la Rochelle
,
V Richard
,
J L Dubois-Randé
,
E Roupie
,
J F Giudicelli
,
L Hittinger
,
and
A Berdeaux
Potassium channel openers dilate large epicardial coronary arteries in conscious dogs by an indirect, endothelium-dependent mechanism.
J Pharmacol Exp Ther
December 1992
263
:
1091
-
1096
Abstract
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G E DeLander
,
H I Mosberg
,
and
F Porreca
Involvement of adenosine in antinociception produced by spinal or supraspinal receptor-selective opioid agonists: dissociation from gastrointestinal effects in mice.
J Pharmacol Exp Ther
December 1992
263
:
1097
-
1104
Abstract
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M Z Badr
Induction of peroxisomal enzyme activities by di-(2-ethylhexyl) phthalate in thyroidectomized rats with parathyroid replants.
J Pharmacol Exp Ther
December 1992
263
:
1105
-
1110
Abstract
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J J Andazola
,
J A Underwood
,
M Chiono
,
O A Torres
,
and
C A Herman
Leukotriene B4 and leukotriene B5 have binding sites on lung membranes and cause contraction of bullfrog lung.
J Pharmacol Exp Ther
December 1992
263
:
1111
-
1117
Abstract
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D R Compton
,
L H Gold
,
S J Ward
,
R L Balster
,
and
B R Martin
Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol.
J Pharmacol Exp Ther
December 1992
263
:
1118
-
1126
Abstract
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H Ito
,
K Hidaka
,
K Miyata
,
T Kamato
,
A Nishida
,
and
K Honda
Characterization of YM060, a potent and selective 5-hydroxytryptamine3 receptor antagonist, in rabbit nodose ganglion and N1E-115 neuroblastoma cells.
J Pharmacol Exp Ther
December 1992
263
:
1127
-
1132
Abstract
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B T Gabelt
and
P L Kaufman
Inhibition of outflow facility and accommodative and miotic responses to pilocarpine in rhesus monkeys by muscarinic receptor subtype antagonists.
J Pharmacol Exp Ther
December 1992
263
:
1133
-
1139
Abstract
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U Jaehde
,
M W Langemeijer
,
A G de Boer
,
and
D D Breimer
Cerebrospinal fluid transport and disposition of the quinolones ciprofloxacin and pefloxacin in rats.
J Pharmacol Exp Ther
December 1992
263
:
1140
-
1146
Abstract
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T A Pugsley
,
C L Christofferson
,
A Corbin
,
H A DeWald
,
S Demattos
,
L T Meltzer
,
S L Myers
,
Y H Shih
,
S Z Whetzel
,
and
J N Wiley
Pharmacological characterization of PD 118717, a putative piperazinyl benzopyranone dopamine autoreceptor agonist.
J Pharmacol Exp Ther
December 1992
263
:
1147
-
1158
Abstract
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L Cook
,
S W Tam
,
and
K W Rohrbach
DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'- oxoethyl)piperidine HBr], a potential antipsychotic agent: preclinical behavioral effects.
J Pharmacol Exp Ther
December 1992
263
:
1159
-
1166
Abstract
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S W Tam
,
G F Steinfels
,
P J Gilligan
,
W K Schmidt
,
and
L Cook
DuP 734 [1-(cyclopropylmethyl)-4-(2'(4''-fluorophenyl)-2'-oxoethyl)- piperidine HBr], a sigma and 5-hydroxytryptamine2 receptor antagonist: receptor-binding, electrophysiological and neuropharmacological profiles.
J Pharmacol Exp Ther
December 1992
263
:
1167
-
1174
Abstract
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S G Culp
,
D Rominger
,
S W Tam
,
and
E B De Souza
[3H]DuP 734 [1-(cyclopropylmethyl)-4-(2'-(4''-fluorophenyl)-2'- oxoethyl)-piperidine HBr]: a receptor binding profile of a high-affinity novel sigma receptor ligand in guinea pig brain.
J Pharmacol Exp Ther
December 1992
263
:
1175
-
1187
Abstract
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Y X Wang
and
D P Brooks
The role of adenosine in glycine-induced glomerular hyperfiltration in rats.
J Pharmacol Exp Ther
December 1992
263
:
1188
-
1194
Abstract
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T J Torphy
,
H L Zhou
,
and
L B Cieslinski
Stimulation of beta adrenoceptors in a human monocyte cell line (U937) up-regulates cyclic AMP-specific phosphodiesterase activity.
J Pharmacol Exp Ther
December 1992
263
:
1195
-
1205
Abstract
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J L Vatier
,
Z Gao
,
X M Fu-Cheng
,
M T Vitre
,
D A Levy
,
G Cohen
,
and
M Mignon
Evidence for the interaction between antacid and gastric mucosa using an "artificial stomach" model including gastric mucosa.
J Pharmacol Exp Ther
December 1992
263
:
1206
-
1211
Abstract
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F P Monnet
,
A Fournier
,
G Debonnel
,
and
C de Montigny
Neuropeptide Y potentiates selectively the N-methyl-D-aspartate response in the rat CA3 dorsal hippocampus. I. Involvement of an atypical neuropeptide Y receptor.
J Pharmacol Exp Ther
December 1992
263
:
1212
-
1218
Abstract
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F P Monnet
,
G Debonnel
,
A Fournier
,
and
C de Montigny
Neuropeptide Y potentiates the N-methyl-D-aspartate response in the CA3 dorsal hippocampus. II. Involvement of a subtype of sigma receptor.
J Pharmacol Exp Ther
December 1992
263
:
1219
-
1225
Abstract
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A Claing
,
S Télémaque
,
A Cadieux
,
A Fournier
,
D Regoli
,
and
P D'Orléans-Juste
Nonadrenergic and noncholinergic arterial dilatation and venoconstriction are mediated by calcitonin gene-related peptide1 and neurokinin-1 receptors, respectively, in the mesenteric vasculature of the rat after perivascular nerve stimulation.
J Pharmacol Exp Ther
December 1992
263
:
1226
-
1232
Abstract
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O F Schanne
and
R Dumaine
Interaction of taurine with the fast Na-current in isolated rabbit myocytes.
J Pharmacol Exp Ther
December 1992
263
:
1233
-
1240
Abstract
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A Giacometti
,
M Quartaroli
,
G Gaviraghi
,
D Micheli
,
and
D Trist
Analysis of the interaction between lacidipine and BAY K 8644 in two isolated rabbit arteries.
J Pharmacol Exp Ther
December 1992
263
:
1241
-
1247
Abstract
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J Kitanaka
,
H Hashimoto
,
M Gotoh
,
T Mayumi
,
and
A Baba
Mechanism of extracellular ATP-stimulated phosphoinositide hydrolysis in rat glioma C6 cells.
J Pharmacol Exp Ther
December 1992
263
:
1248
-
1252
Abstract
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A Veltmar
,
J Culman
,
F Qadri
,
W Rascher
,
and
T Unger
Involvement of adrenergic and angiotensinergic receptors in the paraventricular nucleus in the angiotensin II-induced vasopressin release.
J Pharmacol Exp Ther
December 1992
263
:
1253
-
1260
Abstract
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C F Toombs
,
N R Norman
,
V E Groppi
,
K S Lee
,
R C Gadwood
,
and
R J Shebuski
Limitation of myocardial injury with the potassium channel opener cromakalim and the nonvasoactive analog U-89,232: vascular vs. cardiac actions in vitro and in vivo.
J Pharmacol Exp Ther
December 1992
263
:
1261
-
1268
Abstract
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R V Considine
,
J R Sherwin
,
and
L L Simpson
Role of protein kinase C in short-term transmission at the mammalian neuromuscular junction.
J Pharmacol Exp Ther
December 1992
263
:
1269
-
1274
Abstract
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C D Mahle
,
H L Wiener
,
F D Yocca
,
and
S Maayani
Allosteric interactions between the binding sites of receptor agonists and guanine nucleotides: a comparative study of the 5-hydroxytryptamine1A and adenosine A1 receptor systems in rat hippocampal membranes.
J Pharmacol Exp Ther
December 1992
263
:
1275
-
1284
Abstract
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C van Horne
,
B J Hoffer
,
I Strömberg
,
and
G A Gerhardt
Clearance and diffusion of locally applied dopamine in normal and 6-hydroxydopamine-lesioned rat striatum.
J Pharmacol Exp Ther
December 1992
263
:
1285
-
1292
Abstract
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Y Takata
,
F Shimada
,
and
H Kato
Differential effects of diazoxide, cromakalim and pinacidil on adrenergic neurotransmission and 86Rb+ efflux in rat brain cortical slices.
J Pharmacol Exp Ther
December 1992
263
:
1293
-
1301
Abstract
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A Miyake
,
H Yamamoto
,
Y Takebayashi
,
H Imai
,
and
K Honda
The novel natural product YM-26567-1 [(+)-trans-4-(3-dodecanoyl-2,4,6- trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman]: a competitive inhibitor of group II phospholipase A2.
J Pharmacol Exp Ther
December 1992
263
:
1302
-
1307
Abstract
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S J Weber
,
D L Greene
,
V J Hruby
,
H I Yamamura
,
F Porreca
,
and
T P Davis
Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration.
J Pharmacol Exp Ther
December 1992
263
:
1308
-
1316
Abstract
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P Lazarovici
and
P I Lelkes
Pardaxin induces exocytosis in bovine adrenal medullary chromaffin cells independent of calcium.
J Pharmacol Exp Ther
December 1992
263
:
1317
-
1326
Abstract
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I Angel
,
H Schoemaker
,
S Arbilla
,
A M Galzin
,
C Berry
,
R Niddam
,
C Pimoule
,
M Sevrin
,
A Wick
,
and
S Z Langer
SL 84.0418: a novel, potent and selective alpha-2 adrenoceptor antagonist: in vitro pharmacological profile.
J Pharmacol Exp Ther
December 1992
263
:
1327
-
1333
Abstract
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H Bergstrand
,
T Eriksson
,
A Hallberg
,
B Johansson
,
K Karabelas
,
P Michelsen
,
and
A Nybom
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase.
J Pharmacol Exp Ther
December 1992
263
:
1334
-
1346
Abstract
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A Wada
,
Y Uezono
,
M Arita
,
T Yuhi
,
H Kobayashi
,
N Yanagihara
,
and
F Izumi
Cooperative modulation of voltage-dependent sodium channels by brevetoxin and classical neurotoxins in cultured bovine adrenal medullary cells.
J Pharmacol Exp Ther
December 1992
263
:
1347
-
1351
Abstract
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R H Schwinger
,
M Böhm
,
R Uhlmann
,
K La Rosée
,
A Koch
,
and
E Erdmann
Increase of the extracellular magnesium concentration reduces cardiac glycoside toxicity in the human myocardium.
J Pharmacol Exp Ther
December 1992
263
:
1352
-
1359
Abstract
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M Serra
,
M C Foddi
,
C A Ghiani
,
M A Melis
,
C Motzo
,
A Concas
,
E Sanna
,
and
G Biggio
Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil.
J Pharmacol Exp Ther
December 1992
263
:
1360
-
1368
Abstract
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J P Beregi
,
D Escande
,
N Coudray
,
P Mery
,
M Mestre
,
D Chemla
,
and
Y Lecarpentier
Positive inotropic effects of RP 62719, a new pure class III antiarrhythmic agent, on guinea pig myocardium.
J Pharmacol Exp Ther
December 1992
263
:
1369
-
1376
Abstract
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A Trifilieff
,
A Da Silva
,
Y Landry
,
and
J P Gies
Effect of Hoe 140, a new B2 noncompetitive antagonist, on guinea pig tracheal bradykinin receptors.
J Pharmacol Exp Ther
December 1992
263
:
1377
-
1382
Abstract
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B F Thomas
,
X Wei
,
and
B R Martin
Characterization and autoradiographic localization of the cannabinoid binding site in rat brain using [3H]11-OH-delta 9-THC-DMH.
J Pharmacol Exp Ther
December 1992
263
:
1383
-
1390
Abstract
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K A Frey
and
M M Howland
Quantitative autoradiography of muscarinic cholinergic receptor binding in the rat brain: distinction of receptor subtypes in antagonist competition assays.
J Pharmacol Exp Ther
December 1992
263
:
1391
-
1400
Abstract
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B X Carlson
,
A M Mans
,
R A Hawkins
,
and
H A Baghdoyan
Pentobarbital-enhanced [3H]flunitrazepam binding throughout the rat brain: an autoradiographic study.
J Pharmacol Exp Ther
December 1992
263
:
1401
-
1414
Abstract
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N M Appel
,
J D Robbins
,
E B De Souza
,
and
K B Seamon
[125I]-labeled forskolin analogs which discriminate adenylyl cyclase and a glucose transporter: pharmacological characterization and localization of binding sites in rat brain by in vitro receptor autoradiography.
J Pharmacol Exp Ther
December 1992
263
:
1415
-
1423
Abstract
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C C Deck
,
T E Raya
,
M A Gaballa
,
and
S Goldman
Baroreflex control of heart rate in rats with heart failure after myocardial infarction: effects of captopril.
J Pharmacol Exp Ther
December 1992
263
:
1424
-
1431
Abstract
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M B Genter
,
J Llorens
,
J P O'Callaghan
,
D B Peele
,
K T Morgan
,
and
K M Crofton
Olfactory toxicity of beta,beta'-iminodipropionitrile in the rat.
J Pharmacol Exp Ther
December 1992
263
:
1432
-
1439
Abstract
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S D Skaper
,
L Facci
,
N Schiavo
,
G Vantini
,
F Moroni
,
R Dal Toso
,
and
A Leon
Characterization of 2,4,5-trihydroxyphenylalanine neurotoxicity in vitro and protective effects of ganglioside GM1: implications for Parkinson's disease.
J Pharmacol Exp Ther
December 1992
263
:
1440
-
1446
Abstract
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F Amenta
,
F Ferrante
,
A Rossodivita
,
and
A Ricci
Pharmacological characterization and autoradiographic localization of dopamine receptors in human epicardial arteries.
J Pharmacol Exp Ther
December 1992
263
:
1447
-
1453
Abstract
Full Text (PDF)
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P E Simson
,
K B Johnson
,
H A Jurevics
,
H E Criswell
,
T C Napier
,
G E Duncan
,
R A Mueller
,
and
G R Breese
Augmented sensitivity of D1-dopamine receptors in lateral but not medial striatum after 6-hydroxydopamine-induced lesions in the neonatal rat.
J Pharmacol Exp Ther
December 1992
263
:
1454
-
1463
Abstract
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S J Kohlhepp
,
D N McGregor
,
S J Cohen
,
M E Kohlhepp
,
and
D N Gilbert
Determinants of the in vitro interaction of polyaspartic acid and aminoglycoside antibiotics.
J Pharmacol Exp Ther
December 1992
263
:
1464
-
1470
Abstract
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X Boulenc
,
M Bourrie
,
I Fabre
,
C Roque
,
H Joyeux
,
Y Berger
,
and
G Fabre
Regulation of cytochrome P450IA1 gene expression in a human intestinal cell line, Caco-2.
J Pharmacol Exp Ther
December 1992
263
:
1471
-
1478
Abstract
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J Zhu
,
W Li
,
M L Toews
,
and
T D Hexum
Neuropeptide Y inhibits forskolin-stimulated adenylate cyclase in bovine adrenal chromaffin cells via a pertussis toxin-sensitive process.
J Pharmacol Exp Ther
December 1992
263
:
1479
-
1486
Abstract
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J Kukkonen
,
P Ojala
,
J Näsman
,
H Hämäläinen
,
J Heikkilä
,
and
K E Akerman
Muscarinic receptor subtypes in human neuroblastoma cell lines SH-SY5Y and IMR-32 as determined by receptor binding, Ca++ mobilization and northern blotting.
J Pharmacol Exp Ther
December 1992
263
:
1487
-
1493
Abstract
Full Text (PDF)
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December 1992; 263 (3)
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