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Table of Contents
August 1992; 262 (2)
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M J Millan
,
J M Rivet
,
H Canton
,
F Lejeune
,
K Bervoets
,
M Brocco
,
A Gobert
,
B Lefebvre de Ladonchamps
,
S Le Marouille-Girardon
,
and
L Verriele
S 14671: a naphtylpiperazine 5-hydroxytryptamine1A agonist of exceptional potency and high efficacy possessing antagonist activity at 5-hydroxytryptamine1C/2 receptors.
J Pharmacol Exp Ther
August 1992
262
:
451
-
463
Abstract
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Y Itzhak
and
I Stein
Sensitization to the toxic effects of cocaine in mice is associated with the regulation of N-methyl-D-aspartate receptors in the cortex.
J Pharmacol Exp Ther
August 1992
262
:
464
-
470
Abstract
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M L Toews
,
J M Hoffman
,
S A Liewer
,
and
L J Arneson-Rotert
Serum-induced sensitization of cyclic AMP accumulation in C62B rat glioma cells.
J Pharmacol Exp Ther
August 1992
262
:
471
-
478
Abstract
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L H Gold
,
R L Balster
,
R L Barrett
,
D T Britt
,
and
B R Martin
A comparison of the discriminative stimulus properties of delta 9-tetrahydrocannabinol and CP 55,940 in rats and rhesus monkeys.
J Pharmacol Exp Ther
August 1992
262
:
479
-
486
Abstract
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J E Dildy-Mayfield
and
R A Harris
Comparison of ethanol sensitivity of rat brain kainate, DL-alpha-amino-3-hydroxy-5-methyl-4-isoxalone proprionic acid and N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
J Pharmacol Exp Ther
August 1992
262
:
487
-
494
Abstract
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M Schwanstecher
,
S Behrends
,
C Brandt
,
and
U Panten
The binding properties of the solubilized sulfonylurea receptor from a pancreatic B-cell line are modulated by the Mg(++)-complex of ATP.
J Pharmacol Exp Ther
August 1992
262
:
495
-
502
Abstract
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R P Koopmans
,
M C Braat
,
B Oosterhuis
,
and
C J van Boxtel
Time-dependent effects of dexamethasone administration on the suppression of plasma hydrocortisone, assessed with a pharmacokinetic model.
J Pharmacol Exp Ther
August 1992
262
:
503
-
508
Abstract
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M C Braat
,
B Oosterhuis
,
R P Koopmans
,
J M Meewis
,
and
C J Van Boxtel
Kinetic-dynamic modeling of lymphocytopenia induced by the combined action of dexamethasone and hydrocortisone in humans, after inhalation and intravenous administration of dexamethasone.
J Pharmacol Exp Ther
August 1992
262
:
509
-
515
Abstract
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D Chemla
,
E Scalbert
,
P Desche
,
J C Pourny
,
F Lambert
,
and
Y Lecarpentier
Effects of perindopril on myocardial inotropy, lusitropy and economy, and on diaphragmatic contractility in the cardiomyopathic Syrian hamster.
J Pharmacol Exp Ther
August 1992
262
:
516
-
525
Abstract
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Q Jiang
,
A Seyed-Mozaffari
,
S Archer
,
and
J M Bidlack
Antinociceptive properties of two alkylating derivatives of morphinone: 14 beta-(thioglycolamido)-7,8-dihydromorphinone (TAMO) and 14 beta-(bromoacetamido)-7,8-dihydromorphinone (H2BAMO).
J Pharmacol Exp Ther
August 1992
262
:
526
-
531
Abstract
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N M Deighton
,
S Motomura
,
S Bals
,
H R Zerkowski
,
and
O E Brodde
Characterization of the beta adrenoceptor subtype(s) mediating the positive inotropic effects of epinine, dopamine, dobutamine, denopamine and xamoterol in isolated human right atrium.
J Pharmacol Exp Ther
August 1992
262
:
532
-
538
Abstract
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K Williams
,
L M Pullan
,
C Romano
,
R J Powel
,
A I Salama
,
and
P B Molinoff
An antagonist/partial agonist at the polyamine recognition site of the N-methyl-D-aspartate receptor that alters the properties of the glutamate recognition site.
J Pharmacol Exp Ther
August 1992
262
:
539
-
544
Abstract
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N A Moore
,
N C Tye
,
M S Axton
,
and
F C Risius
The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent.
J Pharmacol Exp Ther
August 1992
262
:
545
-
551
Abstract
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I Van Liefde
,
A Van Witzenburg
,
and
G Vauquelin
Multiple beta adrenergic receptor subclasses mediate the l-isoproterenol-induced lipolytic response in rat adipocytes.
J Pharmacol Exp Ther
August 1992
262
:
552
-
558
Abstract
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B F Ramos
,
Y Zhang
,
V Angkachatchai
,
and
B A Jakschik
Mast cell mediators regulate vascular permeability changes in Arthus reaction.
J Pharmacol Exp Ther
August 1992
262
:
559
-
565
Abstract
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B E Wood
,
S E O'Connor
,
and
P Leff
Adenosine 5'-(2-fluorodiphosphate) is not a selective P2Y purinoceptor agonist in the rabbit jugular vein.
J Pharmacol Exp Ther
August 1992
262
:
566
-
569
Abstract
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H Ninomiya
,
Y Uchida
,
M Saotome
,
A Nomura
,
H Ohse
,
H Matsumoto
,
F Hirata
,
and
S Hasegawa
Endothelins constrict guinea pig tracheas by multiple mechanisms.
J Pharmacol Exp Ther
August 1992
262
:
570
-
576
Abstract
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M Narita
,
Y Furukawa
,
M Murakami
,
M Takei
,
L M Ren
,
and
S Chiba
Parasympatholytic effects of vecuronium are mediated by nicotinic and muscarinic receptors in hearts of anesthetized dogs.
J Pharmacol Exp Ther
August 1992
262
:
577
-
583
Abstract
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S J Wall
,
R P Yasuda
,
M Li
,
W Ciesla
,
and
B B Wolfe
Differential regulation of subtypes m1-m5 of muscarinic receptors in forebrain by chronic atropine administration.
J Pharmacol Exp Ther
August 1992
262
:
584
-
588
Abstract
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S Yamada
,
Y Matsuoka
,
Y Kato
,
R Kimura
,
and
O Inagaki
A sustained occupancy in vivo of cardiovascular calcium antagonist receptors by mepirodipine and its relation to pharmacodynamic effect in spontaneously hypertensive rats.
J Pharmacol Exp Ther
August 1992
262
:
589
-
594
Abstract
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E H Ohlstein
,
M Gellai
,
D P Brooks
,
L Vickery
,
J Jugus
,
A Sulpizio
,
R R Ruffolo, Jr
,
J Weinstock
,
and
R M Edwards
The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism.
J Pharmacol Exp Ther
August 1992
262
:
595
-
601
Abstract
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S R Tella
,
C W Schindler
,
and
S R Goldberg
Cardiovascular effects of cocaine in conscious rats: relative significance of central sympathetic stimulation and peripheral neuronal monoamine uptake and release mechanisms.
J Pharmacol Exp Ther
August 1992
262
:
602
-
610
Abstract
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C L Cioffi
,
R F Neale, Jr
,
R H Jackson
,
and
M A Sills
Characterization of rat lung endothelin receptor subtypes which are coupled to phosphoinositide hydrolysis.
J Pharmacol Exp Ther
August 1992
262
:
611
-
618
Abstract
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W J Dutczak
and
N Ballatori
gamma-Glutamyltransferase-dependent biliary-hepatic recycling of methyl mercury in the guinea pig.
J Pharmacol Exp Ther
August 1992
262
:
619
-
623
Abstract
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A C Petropoulos
,
S L Winbery
,
and
L A Barker
Effect of short-term treatment with gastrin and related peptides on gastrointestinal histamine H2-receptors.
J Pharmacol Exp Ther
August 1992
262
:
624
-
631
Abstract
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M Naka
,
D E Mais
,
T A Morinelli
,
N Hamanaka
,
J E Oatis, Jr
,
and
P V Halushka
7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors.
J Pharmacol Exp Ther
August 1992
262
:
632
-
637
Abstract
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D N Jones
and
S G Holtzman
Interaction between opioid antagonists and amphetamine: evidence for mediation by central delta opioid receptors.
J Pharmacol Exp Ther
August 1992
262
:
638
-
645
Abstract
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J L Ellis
and
B J Undem
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea.
J Pharmacol Exp Ther
August 1992
262
:
646
-
653
Abstract
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W F Hood
,
N M Gray
,
M S Dappen
,
G B Watson
,
R P Compton
,
A A Cordi
,
T H Lanthorn
,
and
J B Monahan
Characterization of indole-2-carboxylate derivatives as antagonists of N-methyl-D-aspartate receptor activity at the associated glycine recognition site.
J Pharmacol Exp Ther
August 1992
262
:
654
-
660
Abstract
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I N Pessah
,
F C Mohr
,
M Schiedt
,
and
R M Joy
Stereoselective modulation of ryanodine-sensitive calcium channels by the delta isomer of hexachlorocyclohexane (delta-HCH).
J Pharmacol Exp Ther
August 1992
262
:
661
-
669
Abstract
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Y Q Xu
,
A S Pickoff
,
and
C W Clarkson
Developmental changes in the effects of lidocaine on sodium channels in rat cardiac myocytes.
J Pharmacol Exp Ther
August 1992
262
:
670
-
676
Abstract
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P P Bertrand
and
J J Galligan
Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine.
J Pharmacol Exp Ther
August 1992
262
:
677
-
682
Abstract
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K Yeleswaram
,
D W Rurak
,
C Hall
,
M R Wright
,
and
J E Axelson
Pharmacokinetics and pharmacodynamics of labetalol in the pregnant sheep.
J Pharmacol Exp Ther
August 1992
262
:
683
-
691
Abstract
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N A Darmani
,
B R Martin
,
and
R A Glennon
Behavioral evidence for differential adaptation of the serotonergic system after acute and chronic treatment with (+/- )-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) or ketanserin.
J Pharmacol Exp Ther
August 1992
262
:
692
-
698
Abstract
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C R Bowden
,
S J Voina
,
R Woestenborghs
,
R De Coster
,
and
J Heykants
Stimulation by risperidone of rat prolactin secretion in vivo and in cultured pituitary cells in vitro.
J Pharmacol Exp Ther
August 1992
262
:
699
-
706
Abstract
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K L Preston
,
B Wolf
,
J J Guarino
,
and
R R Griffiths
Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability.
J Pharmacol Exp Ther
August 1992
262
:
707
-
720
Abstract
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S R Smith
,
A W Watnick
,
R W Bryant
,
M Billah
,
and
M I Siegel
Actions of a 5-lipoxygenase inhibitor, Sch 40120, on acute inflammatory responses.
J Pharmacol Exp Ther
August 1992
262
:
721
-
728
Abstract
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G Wiemer
and
K Wirth
Production of cyclic GMP via activation of B1 and B2 kinin receptors in cultured bovine aortic endothelial cells.
J Pharmacol Exp Ther
August 1992
262
:
729
-
733
Abstract
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R T McCabe
,
A H Newman
,
and
P Skolnick
AHN 683: a fluorescent ligand for peripheral-type benzodiazepine receptors.
J Pharmacol Exp Ther
August 1992
262
:
734
-
740
Abstract
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J S Fedan
and
D G Frazer
Influence of epithelium on the reactivity of guinea pig isolated, perfused trachea to bronchoactive drugs.
J Pharmacol Exp Ther
August 1992
262
:
741
-
750
Abstract
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S L Pugh
,
M S Boone
,
and
M W Emmett-Oglesby
Tolerance, cross-tolerance and withdrawal in rats made dependent on diazepam.
J Pharmacol Exp Ther
August 1992
262
:
751
-
758
Abstract
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M Rinaldi-Carmona
,
C Congy
,
V Santucci
,
J Simiand
,
B Gautret
,
G Neliat
,
B Labeeuw
,
G Le Fur
,
P Soubrie
,
and
J C Breliere
Biochemical and pharmacological properties of SR 46349B, a new potent and selective 5-hydroxytryptamine2 receptor antagonist.
J Pharmacol Exp Ther
August 1992
262
:
759
-
768
Abstract
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R Invernizzi
,
L Pozzi
,
F Vallebuona
,
I Bonini
,
G Sacchetti
,
and
R Samanin
Effect of amineptine on regional extracellular concentrations of dopamine and noradrenaline in the rat brain.
J Pharmacol Exp Ther
August 1992
262
:
769
-
774
Abstract
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G Jagadeesh
and
R C Deth
Phorbol ester and staurosporine modulation of antagonist and agonist binding to alpha-2 adrenergic receptors: differential influence on Na+ versus guanylylnucleotide regulation.
J Pharmacol Exp Ther
August 1992
262
:
775
-
783
Abstract
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G P Dubé
,
D E Mais
,
J A Jakubowski
,
K A Brune
,
B G Utterback
,
T A True
,
L E Rinkema
,
and
W L Kurtz
In vitro characterization of a novel TXA2/PGH2 receptor ligand (S-145) in platelets and vascular and airway smooth muscle.
J Pharmacol Exp Ther
August 1992
262
:
784
-
791
Abstract
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M G Corda
,
M Orlandi
,
D Lecca
,
and
O Giorgi
Decrease in GABAergic function induced by pentylenetetrazol kindling in rats: antagonism by MK-801.
J Pharmacol Exp Ther
August 1992
262
:
792
-
800
Abstract
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D W Sapp
,
U Witte
,
D M Turner
,
B Longoni
,
N Kokka
,
and
R W Olsen
Regional variation in steroid anesthetic modulation of [35S]TBPS binding to gamma-aminobutyric acidA receptors in rat brain.
J Pharmacol Exp Ther
August 1992
262
:
801
-
808
Abstract
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E Carmeliet
Voltage- and time-dependent block of the delayed K+ current in cardiac myocytes by dofetilide.
J Pharmacol Exp Ther
August 1992
262
:
809
-
817
Abstract
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V Mares
,
M Baudysová
,
J Kvítek
,
V Hnatovicz
,
J Cervená
,
J Vacík
,
and
J Folbergrová
Accumulation of boron-10 (10B) in cell cultures exposed to mercaptododecaborate (Na2H(11)10B12SH) used for the neutron capture therapy of brain tumors.
J Pharmacol Exp Ther
August 1992
262
:
818
-
822
Abstract
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D L Somers
and
R M Beckstead
N-methyl-D-aspartate receptor antagonism alters substance P and met5-enkephalin biosynthesis in neurons of the rat striatum.
J Pharmacol Exp Ther
August 1992
262
:
823
-
833
Abstract
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T Whittem
,
R G Schnellmann
,
and
D C Ferguson
Poly-L-aspartic acid does but triiodothyronine does not protect against gentamicin-induced cytotoxicity in the porcine kidney cell line LLC-PK1.
J Pharmacol Exp Ther
August 1992
262
:
834
-
840
Abstract
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M Kimura
,
K Maeda
,
Y Harasawa
,
Y Ohno
,
M Nakamura
,
I Sakurai
,
and
S Hayashi
Recovery of endothelium-dependent responses by reseeding endothelial cells in culture onto the denuded coronary artery.
J Pharmacol Exp Ther
August 1992
262
:
841
-
849
Abstract
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E Montcalm-Mazzilli
and
T Shea-Donohue
Effect of leukotriene D4 on gastric emptying and secretion in rhesus monkeys.
J Pharmacol Exp Ther
August 1992
262
:
850
-
854
Abstract
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K B Johnson
,
H E Criswell
,
K F Jensen
,
P E Simson
,
R A Mueller
,
and
G R Breese
Comparison of the D1-dopamine agonists SKF-38393 and A-68930 in neonatal 6-hydroxydopamine-lesioned rats: behavioral effects and induction of c-fos-like immunoreactivity.
J Pharmacol Exp Ther
August 1992
262
:
855
-
865
Abstract
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P B Jacobson
and
R S Jacobs
Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part I: Physiological and biochemical studies in murine inflammatory models.
J Pharmacol Exp Ther
August 1992
262
:
866
-
873
Abstract
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P B Jacobson
and
R S Jacobs
Fuscoside: an anti-inflammatory marine natural product which selectively inhibits 5-lipoxygenase. Part II: Biochemical studies in the human neutrophil.
J Pharmacol Exp Ther
August 1992
262
:
874
-
882
Abstract
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