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Table of Contents
February 1992; 260 (2)
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L A Merkel
,
R W Lappe
,
L M Rivera
,
B F Cox
,
and
M H Perrone
Demonstration of vasorelaxant activity with an A1-selective adenosine agonist in porcine coronary artery: involvement of potassium channels.
J Pharmacol Exp Ther
February 1992
260
:
437
-
443
Abstract
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D Beauchamp
,
P Gourde
,
G Thériault
,
and
M G Bergeron
Age-dependent gentamicin experimental nephrotoxicity.
J Pharmacol Exp Ther
February 1992
260
:
444
-
449
Abstract
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S T Kau
,
B B Howe
,
P A Johnston
,
J H Li
,
T J Halterman
,
J S Zuzack
,
K Leszczynska
,
C L Yochim
,
J A Schwartz
,
and
R E Giles
Renal and antihypertensive effects of a novel eukalemic diuretic, ICI 207,828.
J Pharmacol Exp Ther
February 1992
260
:
450
-
457
Abstract
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P A Johnston
and
S T Kau
Evaluation of the renal site of action of a novel, eukalemic diuretic, ICI 207,828.
J Pharmacol Exp Ther
February 1992
260
:
458
-
462
Abstract
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I Salonen
,
P Pakarinen
,
and
I Huhtaniemi
Effect of chronic ethanol diet on expression of gonadotropin genes in the male rat.
J Pharmacol Exp Ther
February 1992
260
:
463
-
467
Abstract
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M Floreani
and
F Carpenedo
The catecholamine-mediated positive inotropic effect of simple quinones is related to superoxide anion generation.
J Pharmacol Exp Ther
February 1992
260
:
468
-
473
Abstract
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S T Ahlers
,
B A Weissman
,
and
J E Barrett
Antagonism studies with BMY-7378 and NAN-190: effects on 8-hydroxy-2-(di-n-propylamino)tetralin-induced increases in punished responding of pigeons.
J Pharmacol Exp Ther
February 1992
260
:
474
-
481
Abstract
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K Inui
,
Y Tomita
,
T Katsura
,
T Okano
,
M Takano
,
and
R Hori
H+ coupled active transport of bestatin via the dipeptide transport system in rabbit intestinal brush-border membranes.
J Pharmacol Exp Ther
February 1992
260
:
482
-
486
Abstract
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B Ulrich
,
F J Frey
,
R F Speck
,
and
B M Frey
Pharmacokinetics/pharmacodynamics of ketoconazole-prednisolone interaction.
J Pharmacol Exp Ther
February 1992
260
:
487
-
490
Abstract
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D D Gretler
,
K C Jones
,
and
M B Murphy
5-Hydroxytryptamine receptor activity of the dopamine receptor agonist fenoldopam in canine tracheal smooth muscle.
J Pharmacol Exp Ther
February 1992
260
:
491
-
498
Abstract
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H Matsushita
,
H Suzuki
,
Y Sugiyama
,
Y Sawada
,
T Iga
,
Y Kawaguchi
,
and
M Hanano
Effect of benzylpenicillin on the disposition of cefodizime in rats: no net effect on total clearance due to decreased hepatobiliary clearance and increased renal clearance.
J Pharmacol Exp Ther
February 1992
260
:
499
-
504
Abstract
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J Uemasu
,
K Godai
,
A Tokumoto
,
and
H Kawasaki
Reduced glomerular hypertrophy by somatostatin analog, SMS 201-995, in the subtotal nephrectomized rats fed high-protein meals.
J Pharmacol Exp Ther
February 1992
260
:
505
-
508
Abstract
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A D Miller
and
S Nonaka
Mechanisms of vomiting induced by serotonin-3 receptor agonists in the cat: effect of vagotomy, splanchnicectomy or area postrema lesion.
J Pharmacol Exp Ther
February 1992
260
:
509
-
517
Abstract
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A Mattia
,
S C Farmer
,
A E Takemori
,
M Sultana
,
P S Portoghese
,
H I Mosberg
,
W D Bowen
,
and
F Porreca
Spinal opioid delta antinociception in the mouse: mediation by a 5'-NTII-sensitive delta receptor subtype.
J Pharmacol Exp Ther
February 1992
260
:
518
-
525
Abstract
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A R Almeida
,
D Bunnachak
,
M Burnier
,
J F Wetzels
,
T J Burke
,
and
R W Schrier
Time-dependent protective effects of calcium channel blockers on anoxia- and hypoxia-induced proximal tubule injury.
J Pharmacol Exp Ther
February 1992
260
:
526
-
532
Abstract
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J W Dailey
,
Q S Yan
,
P K Mishra
,
R L Burger
,
and
P C Jobe
Effects of fluoxetine on convulsions and on brain serotonin as detected by microdialysis in genetically epilepsy-prone rats.
J Pharmacol Exp Ther
February 1992
260
:
533
-
540
Abstract
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S F Liu
,
D E Crawley
,
T W Evans
,
and
P J Barnes
Endothelium-dependent nonadrenergic, noncholinergic neural relaxation in guinea pig pulmonary artery.
J Pharmacol Exp Ther
February 1992
260
:
541
-
548
Abstract
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C Moummi
,
G W Gullikson
,
and
T S Gaginella
Effect of endothelin-1 on guinea pig gallbladder smooth muscle in vitro.
J Pharmacol Exp Ther
February 1992
260
:
549
-
553
Abstract
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S Zbaida
and
W G Levine
Role of electronic factors in binding and reduction of azo dyes by hepatic microsomes.
J Pharmacol Exp Ther
February 1992
260
:
554
-
561
Abstract
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C B Hubner
and
C Kornetsky
Heroin, 6-acetylmorphine and morphine effects on threshold for rewarding and aversive brain stimulation.
J Pharmacol Exp Ther
February 1992
260
:
562
-
567
Abstract
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D J Friedman
,
D N Krause
,
and
S P Duckles
Complex prejunctional actions of the D2 dopamine agonists N-0923 and N-0924 in the rat tail artery.
J Pharmacol Exp Ther
February 1992
260
:
568
-
575
Abstract
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C Bolden
,
B Cusack
,
and
E Richelson
Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells.
J Pharmacol Exp Ther
February 1992
260
:
576
-
580
Abstract
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T W Molitor
,
A Morilla
,
J M Risdahl
,
M P Murtaugh
,
C C Chao
,
and
P K Peterson
Chronic morphine administration impairs cell-mediated immune responses in swine.
J Pharmacol Exp Ther
February 1992
260
:
581
-
586
Abstract
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J A Sandberg
and
G D Olsen
Cocaine and metabolite concentrations in the fetal guinea pig after chronic maternal cocaine administration.
J Pharmacol Exp Ther
February 1992
260
:
587
-
591
Abstract
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K D Keef
,
J S Pasco
,
and
D M Eckman
Purinergic relaxation and hyperpolarization in guinea pig and rabbit coronary artery: role of the endothelium.
J Pharmacol Exp Ther
February 1992
260
:
592
-
600
Abstract
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A Keshavarzian
,
J H Gordon
,
C Willson
,
G Urban
,
and
J Z Fields
Chronic ethanol feeding produces a muscarinic receptor upregulation, but not a muscarinic supersensitivity in lower esophageal sphincter muscle.
J Pharmacol Exp Ther
February 1992
260
:
601
-
607
Abstract
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J T Dalton
,
M D Harrington
,
and
J L Au
Evidence of significant absorption of antipyrine from urinary bladder of rats.
J Pharmacol Exp Ther
February 1992
260
:
608
-
613
Abstract
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I Matsumoto
,
M R Combs
,
and
D J Jones
Characterization of 5-hydroxytryptamine1B receptors in rat spinal cord via [125I]iodocyanopindolol binding and inhibition of [3H]-5-hydroxytryptamine release.
J Pharmacol Exp Ther
February 1992
260
:
614
-
626
Abstract
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L F Jones
and
M J Brody
Coronary blood flow in rats is dependent on the release of vascular nitric oxide.
J Pharmacol Exp Ther
February 1992
260
:
627
-
631
Abstract
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H I Magazine
,
A B Malik
,
C A Bruner
,
and
T T Andersen
Acetylated endothelin-1 is a constrictor in guinea pig lung vasculature but not in isolated vascular strips.
J Pharmacol Exp Ther
February 1992
260
:
632
-
636
Abstract
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H Nielsen
,
F V Mortensen
,
H K Pilegaard
,
J M Hasenkam
,
and
M J Mulvany
Calcium utilization coupled to stimulation of postjunctional alpha-1 and alpha-2 adrenoceptors in isolated human resistance arteries.
J Pharmacol Exp Ther
February 1992
260
:
637
-
643
Abstract
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F J Miao
and
T J Lee
Regional variation in acute vascular homologous tachyphylaxis.
J Pharmacol Exp Ther
February 1992
260
:
644
-
651
Abstract
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S J Chung
,
S Chong
,
P Seth
,
C Y Jung
,
and
H L Fung
Conversion of nitroglycerin to nitric oxide in microsomes of the bovine coronary artery smooth muscle is not primarily mediated by glutathione-S-transferases.
J Pharmacol Exp Ther
February 1992
260
:
652
-
659
Abstract
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F Dauphin
and
E Hamel
Identification of multiple muscarinic binding site subtypes in cat and human cerebral vasculature.
J Pharmacol Exp Ther
February 1992
260
:
660
-
667
Abstract
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M R Siegfried
,
J Erhardt
,
T Rider
,
X L Ma
,
and
A M Lefer
Cardioprotection and attenuation of endothelial dysfunction by organic nitric oxide donors in myocardial ischemia-reperfusion.
J Pharmacol Exp Ther
February 1992
260
:
668
-
675
Abstract
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G Thomas
and
P W Ramwell
Interaction of non-arginine compounds with the endothelium-derived relaxing factor inhibitor, NG-monomethyl L-arginine.
J Pharmacol Exp Ther
February 1992
260
:
676
-
679
Abstract
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S M Hatfield
and
N W Roehm
Cyclosporine and FK506 inhibition of murine mast cell cytokine production.
J Pharmacol Exp Ther
February 1992
260
:
680
-
688
Abstract
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J G Drewett
,
R J Ziegler
,
and
G J Trachte
Neuromodulatory effects of atrial natriuretic peptides correlate with an inhibition of adenylate cyclase but not an activation of guanylate cyclase.
J Pharmacol Exp Ther
February 1992
260
:
689
-
696
Abstract
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N Toda
,
H Baba
,
Y Tanobe
,
and
T Okamura
Mechanism of relaxation induced by K+ and nicotine in dog duodenal longitudinal muscle.
J Pharmacol Exp Ther
February 1992
260
:
697
-
701
Abstract
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T Notsu
,
I Tanaka
,
M Takano
,
and
A Noma
Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes.
J Pharmacol Exp Ther
February 1992
260
:
702
-
708
Abstract
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A M Elhawary
,
W A Pettinger
,
and
D W Wolff
Subtype-selective alpha-1 adrenoceptor alkylation in the rat kidney and its effect on the vascular pressor response.
J Pharmacol Exp Ther
February 1992
260
:
709
-
713
Abstract
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W S Wong
,
A M Bendele
,
and
J H Fleisch
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
J Pharmacol Exp Ther
February 1992
260
:
714
-
721
Abstract
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J Buchholz
,
H Tsai
,
D Friedman
,
and
S P Duckles
Influence of age on control of norepinephrine release from the rat tail artery.
J Pharmacol Exp Ther
February 1992
260
:
722
-
727
Abstract
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K Yokotani
,
Y Okuma
,
and
Y Osumi
Release of endogenous noradrenaline from the vascularly perfused rat stomach in vitro: modulation by pre- and postsynaptic adrenoceptors.
J Pharmacol Exp Ther
February 1992
260
:
728
-
733
Abstract
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E Brändle
,
G Fritzsch
,
and
J Greven
Affinity of different local anesthetic drugs and catecholamines for the contraluminal transport system for organic cations in proximal tubules of rat kidneys.
J Pharmacol Exp Ther
February 1992
260
:
734
-
741
Abstract
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L Turski
,
P Jacobsen
,
T Honoré
,
and
D N Stephens
Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline.
J Pharmacol Exp Ther
February 1992
260
:
742
-
747
Abstract
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Z Terashita
,
M Kawamura
,
M Takatani
,
S Tsushima
,
Y Imura
,
and
K Nishikawa
Beneficial effects of TCV-309, a novel potent and selective platelet activating factor antagonist in endotoxin and anaphylactic shock in rodents.
J Pharmacol Exp Ther
February 1992
260
:
748
-
755
Abstract
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Z W Hu
,
K Honda
,
F Murad
,
and
B B Hoffman
Prolonged exposure to catecholamines enhances sensitivity of smooth muscle relaxation induced by sodium nitroprusside and atriopeptin.
J Pharmacol Exp Ther
February 1992
260
:
756
-
761
Abstract
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J L Ortiz
,
C Labat
,
X Norel
,
I Gorenne
,
J Verley
,
and
C Brink
Histamine receptors on human isolated pulmonary arterial muscle preparations: effects of endothelial cell removal and nitric oxide inhibitors.
J Pharmacol Exp Ther
February 1992
260
:
762
-
767
Abstract
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J J Beutler
,
W H Boer
,
H A Koomans
,
and
E J Dorhout Mees
Comparative study of the effects of furosemide, ethacrynic acid and bumetanide on the lithium clearance and diluting segment reabsorption in humans.
J Pharmacol Exp Ther
February 1992
260
:
768
-
772
Abstract
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W K MacNaughton
,
A G Catto-Smith
,
and
D G Gall
A role for phospholipid-derived inflammatory mediators in intestinal anaphylaxis in the rat.
J Pharmacol Exp Ther
February 1992
260
:
773
-
779
Abstract
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B Szabo
,
A Schramm
,
and
K Starke
Effect of yohimbine on renal sympathetic nerve activity and renal norepinephrine spillover in anesthetized rabbits.
J Pharmacol Exp Ther
February 1992
260
:
780
-
788
Abstract
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M L Ogletree
and
G T Allen
Interspecies differences in thromboxane receptors: studies with thromboxane receptor antagonists in rat and guinea pig smooth muscles.
J Pharmacol Exp Ther
February 1992
260
:
789
-
794
Abstract
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S Saeki
and
T L Yaksh
Suppression by spinal alpha-2 agonists of motor and autonomic responses evoked by low- and high-intensity thermal stimuli.
J Pharmacol Exp Ther
February 1992
260
:
795
-
802
Abstract
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J D Huizinga
,
J Tomlinson
,
and
J Pintin-Quezada
Involvement of nitric oxide in nerve-mediated inhibition and action of vasoactive intestinal peptide in colonic smooth muscle.
J Pharmacol Exp Ther
February 1992
260
:
803
-
808
Abstract
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J M Herbert
,
D Frehel
,
M P Rosso
,
E Seban
,
C Castet
,
O Pepin
,
J P Maffrand
,
and
G Le Fur
Biochemical and pharmacological activities of SR 26831, a potent and selective elastase inhibitor.
J Pharmacol Exp Ther
February 1992
260
:
809
-
816
Abstract
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J F Bowyer
,
A W Tank
,
G D Newport
,
W Slikker, Jr
,
S F Ali
,
and
R R Holson
The influence of environmental temperature on the transient effects of methamphetamine on dopamine levels and dopamine release in rat striatum.
J Pharmacol Exp Ther
February 1992
260
:
817
-
824
Abstract
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T Sano
,
Y Morishita
,
Y Matsuda
,
and
K Yamada
Pharmacological profile of HS-142-1, a novel nonpeptide atrial natriuretic peptide antagonist of microbial origin. I. Selective inhibition of the actions of natriuretic peptides in anesthetized rats.
J Pharmacol Exp Ther
February 1992
260
:
825
-
831
Abstract
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M F Bureau
,
F De Clerck
,
J Lefort
,
C D Arreto
,
and
B B Vargaftig
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung.
J Pharmacol Exp Ther
February 1992
260
:
832
-
840
Abstract
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K Raynor
and
T Reisine
Differential coupling of somatostatin1 receptors to adenylyl cyclase in the rat striatum vs. the pituitary and other regions of the rat brain.
J Pharmacol Exp Ther
February 1992
260
:
841
-
848
Abstract
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C Nebigil
and
K U Malik
Prostaglandin synthesis elicited by adrenergic stimuli is mediated via alpha-2C and alpha-1A adrenergic receptors in cultured smooth muscle cells of rabbit aorta.
J Pharmacol Exp Ther
February 1992
260
:
849
-
858
Abstract
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R V Considine
,
L L Simpson
,
and
J R Sherwin
Botulinum C2 toxin and steroid production in adrenal Y-1 cells: the role of microfilaments in the toxin-induced increase in steroid release.
J Pharmacol Exp Ther
February 1992
260
:
859
-
864
Abstract
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T J Flammang
,
T Yerokun
,
M S Bryant
,
L H Couch
,
W G Kirlin
,
K J Lee
,
F Ogolla
,
R J Ferguson
,
G Talaska
,
and
D W Hein
Hemoglobin adduct and hepatic- and urinary bladder-DNA adduct levels in rapid and slow acetylator Syrian inbred hamsters administered 2-aminofluorene.
J Pharmacol Exp Ther
February 1992
260
:
865
-
871
Abstract
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S M Sorensen
,
T M Humphreys
,
V L Taylor
,
and
C J Schmidt
5-HT2 receptor antagonists reverse amphetamine-induced slowing of dopaminergic neurons by interfering with stimulated dopamine synthesis.
J Pharmacol Exp Ther
February 1992
260
:
872
-
878
Abstract
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M R Palmer
,
J T Harlan
,
and
K Spuhler
Genetic covariation in low alcohol-sensitive and high alcohol-sensitive selected lines of rats: behavioral and electrophysiological sensitivities to the depressant effects of ethanol and the development of acute neuronal tolerance to ethanol in situ at generation eight.
J Pharmacol Exp Ther
February 1992
260
:
879
-
886
Abstract
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M R Palmer
and
A C Granholm
Electrophysiological effects of ethanol on hippocampal and cerebellar neurons cografted with locus coeruleus in oculo: role of the noradrenergic circuitry.
J Pharmacol Exp Ther
February 1992
260
:
887
-
895
Abstract
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J Benavides
,
B Peny
,
J Allen
,
and
B Scatton
Pharmacological characterization of in vivo [3H]lfenprodil binding sites in the mouse brain.
J Pharmacol Exp Ther
February 1992
260
:
896
-
901
Abstract
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P Soares-da-Silva
,
M H Fernandes
,
A Albino-Teixeira
,
I Azevedo
,
and
M Pestana
Brief transient ischemia induces long-term depletion of norepinephrine without affecting the aromatic amino acid decarboxylase and monoamine oxidase activities in the rat kidney.
J Pharmacol Exp Ther
February 1992
260
:
902
-
908
Abstract
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M D Maines
and
G M Trakshel
Tin-protoporphyrin: a potent inhibitor of hemoprotein-dependent steroidogenesis in rat adrenals and testes.
J Pharmacol Exp Ther
February 1992
260
:
909
-
916
Abstract
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M Yoshioka
,
Y Goda
,
H Togashi
,
M Matsumoto
,
and
H Saito
Pharmacological characterization of 5-hydroxytryptamine-induced apnea in the rat.
J Pharmacol Exp Ther
February 1992
260
:
917
-
924
Abstract
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I A Shalaby
,
B L Chenard
,
M A Prochniak
,
and
T W Butler
Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture.
J Pharmacol Exp Ther
February 1992
260
:
925
-
932
Abstract
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