Table of Contents

October 1991; 259 (1)

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- D K Agrawal,
- D R Bergren,
- P J Byorth,
- and R G Townley
Platelet-activating factor induces nonspecific desensitization to bronchodilators in guinea pigs.
J Pharmacol Exp Ther October 1991 259:1-7
- Abstract
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- R J Klauser,
- W Raake,
- E Meinetsberger,
- and P Zeiller
Antithrombotic and anticoagulant properties of synthetic polyanions: sulfated bis-aldonic acid amides.
J Pharmacol Exp Ther October 1991 259:8-14
- Abstract
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- K Miyata,
- T Kamato,
- A Nishida,
- H Ito,
- Y Katsuyama,
- A Iwai,
- H Yuki,
- M Yamano,
- R Tsutsumi,
- and M Ohta
Pharmacologic profile of (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H- benzimidazole hydrochloride (YM060), a potent and selective 5-hydroxytryptamine3 receptor antagonist, and its enantiomer in the isolated tissue.
J Pharmacol Exp Ther October 1991 259:15-21
- Abstract
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- T Massamiri and
- S P Duckles
Sigma receptor ligands inhibit rat tail artery contractile responses by multiple mechanisms.
J Pharmacol Exp Ther October 1991 259:22-29
- Abstract
- Full Text (PDF)
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- M A Rogawski,
- S Yamaguchi,
- S M Jones,
- K C Rice,
- A Thurkauf,
- and J A Monn
Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine.
J Pharmacol Exp Ther October 1991 259:30-37
- Abstract
- Full Text (PDF)
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- L M Ren,
- Y Furukawa,
- Y Karasawa,
- M Murakami,
- M Takei,
- M Narita,
- and S Chiba
Differential inhibition of neuropeptide Y on the chronotropic and inotropic responses to sympathetic and parasympathetic stimulation in the isolated, perfused dog atrium.
J Pharmacol Exp Ther October 1991 259:38-43
- Abstract
- Full Text (PDF)
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- J M Herbert,
- A Bernat,
- G Valette,
- V Gigo,
- A Lale,
- M C LaPlace,
- L Lespy,
- P Savi,
- J P Maffrand,
- and G Le Fur
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
J Pharmacol Exp Ther October 1991 259:44-51
- Abstract
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- J Yamazaki,
- N Fujita,
- and T Nagao
NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.
J Pharmacol Exp Ther October 1991 259:52-57
- Abstract
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- P A Rittenhouse,
- E A Bakkum,
- and L D Van de Kar
Evidence that the serotonin agonist, DOI, increases renin secretion and blood pressure through both central and peripheral 5-HT2 receptors.
J Pharmacol Exp Ther October 1991 259:58-65
- Abstract
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- W M Pardridge,
- J L Buciak,
- and P M Friden
Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo.
J Pharmacol Exp Ther October 1991 259:66-70
- Abstract
- Full Text (PDF)
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- S N Joshi,
- A J Lonigro,
- R J Secrest,
- and B M Chapnick
Role of endothelium in responses of isolated hepatic vessels to vasoactive agents.
J Pharmacol Exp Ther October 1991 259:71-77
- Abstract
- Full Text (PDF)
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- H J Crowley,
- B Yaremko,
- W M Selig,
- D R Janero,
- C Burghardt,
- A F Welton,
- and M O'Donnell
Pharmacology of a potent platelet-activating factor antagonist: Ro 24-4736.
J Pharmacol Exp Ther October 1991 259:78-85
- Abstract
- Full Text (PDF)
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- Y Yoneda and
- K Ogita
Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques.
J Pharmacol Exp Ther October 1991 259:86-96
- Abstract
- Full Text (PDF)
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- C A Sargent,
- M A Smith,
- S Dzwonczyk,
- P G Sleph,
- and G J Grover
Effect of potassium channel blockade on the anti-ischemic actions of mechanistically diverse agents.
J Pharmacol Exp Ther October 1991 259:97-103
- Abstract
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- A C Myers and
- B J Undem
Functional interactions between capsaicin-sensitive and cholinergic nerves in the guinea pig bronchus.
J Pharmacol Exp Ther October 1991 259:104-109
- Abstract
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- L J Janssen and
- E E Daniel
Depolarizing agents induce oscillations in canine bronchial smooth muscle membrane potential: possible mechanisms.
J Pharmacol Exp Ther October 1991 259:110-117
- Abstract
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- M S D'Almeida and
- W W Lautt
Glucagon pharmacodynamics and modulation of sympathetic nerve and norepinephrine-induced constrictor responses in the superior mesenteric artery of the cat.
J Pharmacol Exp Ther October 1991 259:118-123
- Abstract
- Full Text (PDF)
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- M O Carruba,
- E Nisoli,
- V Garosi,
- M Pizzi,
- M Memo,
- and P Spano
Characterization of monoaminergic receptors in hypothalamic nuclei mediating feeding behavior in rats.
J Pharmacol Exp Ther October 1991 259:124-130
- Abstract
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- R D Buñag,
- D Krizsan-Agbas,
- and H Itoh
Sympathetic activation by chronic insulin treatment in conscious rats.
J Pharmacol Exp Ther October 1991 259:131-138
- Abstract
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- B J Aungst,
- J A Blake,
- and M A Hussain
An in vitro evaluation of metabolism and poor membrane permeation impeding intestinal absorption of leucine enkephalin, and methods to increase absorption.
J Pharmacol Exp Ther October 1991 259:139-145
- Abstract
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- D Aharony,
- C A Catanese,
- and D P Woodhouse
Binding of the novel ligand [4,5-3H-Leu10]substance P to high-affinity NK-1 receptors on guinea pig lung membranes: modulation by GTP analogs and sulfhydryl modifying agents.
J Pharmacol Exp Ther October 1991 259:146-155
- Abstract
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- J B Pritchard,
- R Walden,
- and A Oikari
Dehydroabietic acid, a major anionic contaminant of pulp mill effluent, reduces both active p-aminohippurate transport and passive membrane permeability in isolated renal membranes.
J Pharmacol Exp Ther October 1991 259:156-163
- Abstract
- Full Text (PDF)
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- L Rakotoarisoa,
- C Mironneau,
- I Sayet,
- and J Mironneau
Guanine nucleotide-binding proteins modulate desmethoxyverapamil binding to calcium channels in vascular smooth muscle.
J Pharmacol Exp Ther October 1991 259:164-168
- Abstract
- Full Text (PDF)
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- A M Bendele,
- S M Spaethe,
- D N Benslay,
- and H U Bryant
Anti-inflammatory activity of pergolide, a dopamine receptor agonist.
J Pharmacol Exp Ther October 1991 259:169-175
- Abstract
- Full Text (PDF)
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- D C Eikenburg
Age-related changes in vascular sympathetic neurotransmission in the rat kidney.
J Pharmacol Exp Ther October 1991 259:176-181
- Abstract
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- E Aceto and
- M Vassalle
On the mechanism of the positive inotropy of low concentrations of strophanthidin.
J Pharmacol Exp Ther October 1991 259:182-189
- Abstract
- Full Text (PDF)
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- C Dedieu-Chaufour,
- F Hertz,
- F Caussade,
- and A Cloarec
Pharmacological profile of UP 5145-52, an original antiulcer and antisecretory agent.
J Pharmacol Exp Ther October 1991 259:190-197
- Abstract
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- K J Morrison and
- P M Vanhoutte
Inhibition of airway smooth muscle tone by a phorbol ester in the guinea pig trachea: role of epithelium and receptor reserve of the contractile agent.
J Pharmacol Exp Ther October 1991 259:198-204
- Abstract
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- T Sakurada,
- T Yamada,
- K Tan-no,
- Y Manome,
- S Sakurada,
- K Kisara,
- and M Ohba
Differential effects of substance P analogs on neurokinin 1 receptor agonists in the mouse spinal cord.
J Pharmacol Exp Ther October 1991 259:205-210
- Abstract
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- C S Park,
- T W Honeyman,
- S K Ha,
- H K Choi,
- C L Chung,
- and C D Hong
Mechanisms of ionophore-induced stimulation of renin secretion with special reference to a chemiosmotic hypothesis.
J Pharmacol Exp Ther October 1991 259:211-218
- Abstract
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- N R Levens,
- D Cóte,
- and G Ksander
Inhibition of thromboxane synthetase potentiates the antihypertensive action of an angiotensin-converting enzyme inhibitor by a prostaglandin-dependent but kinin-independent mechanism.
J Pharmacol Exp Ther October 1991 259:219-227
- Abstract
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- G W Dorn, 2nd
Mechanism for homologous downregulation of thromboxane A2 receptors in cultured human chronic myelogenous leukemia (K562) cells.
J Pharmacol Exp Ther October 1991 259:228-234
- Abstract
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- M Nakahiro,
- O Arakawa,
- and T Narahashi
Modulation of gamma-aminobutyric acid receptor-channel complex by alcohols.
J Pharmacol Exp Ther October 1991 259:235-240
- Abstract
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- J M Farley,
- J G Adderholt,
- and T M Dwyer
Cocaine and tracheal epithelial function: effects on short circuit current and neurotransmitter receptors.
J Pharmacol Exp Ther October 1991 259:241-247
- Abstract
- Full Text (PDF)
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- A H Tang,
- S R Franklin,
- C S Himes,
- and P M Ho
Behavioral effects of U-78875, a quinoxalinone anxiolytic with potent benzodiazepine antagonist activity.
J Pharmacol Exp Ther October 1991 259:248-254
- Abstract
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- M D Johnson,
- H Y Wang,
- D Ciechanowski,
- and E Friedman
Reduced G protein function in desensitized rat aorta.
J Pharmacol Exp Ther October 1991 259:255-259
- Abstract
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- J F French,
- L E Lambert,
- and R C Dage
Nitric oxide synthase inhibitors inhibit interleukin-1 beta-induced depression of vascular smooth muscle.
J Pharmacol Exp Ther October 1991 259:260-264
- Abstract
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- J K Saha,
- J N Sengupta,
- and R K Goyal
Effects of bradykinin and bradykinin analogs on the opossum lower esophageal sphincter: characterization of an inhibitory bradykinin receptor.
J Pharmacol Exp Ther October 1991 259:265-273
- Abstract
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- J Hidalgo,
- M Giralt,
- J S Garvey,
- and A Armario
Effect of morphine administration on rat liver metallothionein and zinc metabolism.
J Pharmacol Exp Ther October 1991 259:274-278
- Abstract
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- M G López,
- F Abad,
- C Sancho,
- R de Pascual,
- R Borges,
- R Maroto,
- W Dixon,
- and A G Garcia
Membrane-mediated effects of the steroid 17-alpha-estradiol on adrenal catecholamine release.
J Pharmacol Exp Ther October 1991 259:279-285
- Abstract
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- O Nikodijević,
- R Sarges,
- J W Daly,
- and K A Jacobson
Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.
J Pharmacol Exp Ther October 1991 259:286-294
- Abstract
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- J A Leedham,
- L E Bennett,
- D A Taylor,
- and W W Fleming
Involvement of mu, delta and kappa receptors in morphine-induced tolerance in the guinea pig myenteric plexus.
J Pharmacol Exp Ther October 1991 259:295-301
- Abstract
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- M M Belcheva,
- J Barg,
- R J McHale,
- X M Gao,
- D M Chuang,
- and C J Coscia
Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone.
J Pharmacol Exp Ther October 1991 259:302-309
- Abstract
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- A Rengasamy and
- R A Johns
Characterization of endothelium-derived relaxing factor/nitric oxide synthase from bovine cerebellum and mechanism of modulation by high and low oxygen tensions.
J Pharmacol Exp Ther October 1991 259:310-316
- Abstract
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- P Arner,
- E Kriegholm,
- and P Engfeldt
In vivo interactions between beta-1 and beta-2 adrenoceptors regulate catecholamine tachyphylaxia in human adipose tissue.
J Pharmacol Exp Ther October 1991 259:317-322
- Abstract
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- H S Blaxall,
- T J Murphy,
- J C Baker,
- C Ray,
- and D B Bylund
Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line.
J Pharmacol Exp Ther October 1991 259:323-329
- Abstract
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- L F Tseng and
- K A Collins
Involvement of epsilon and kappa opioid receptors in inhibition of the tail-flick response induced by bremazocine in the mouse.
J Pharmacol Exp Ther October 1991 259:330-336
- Abstract
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- B J Ebersole and
- P B Molinoff
Inhibition of binding of [3H]PN200-110 to membranes from rat brain and heart by ascorbate is mediated by lipid peroxidation.
J Pharmacol Exp Ther October 1991 259:337-344
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- M Buonamici,
- S Mantegani,
- M A Cervini,
- R Maj,
- A C Rossi,
- C Caccia,
- N Carfagna,
- P Carminati,
- and R G Fariello
FCE 23884, substrate-dependent interaction with the dopaminergic system. I. Preclinical behavioral studies.
J Pharmacol Exp Ther October 1991 259:345-355
- Abstract
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- N Carfagna,
- C Caccia,
- S Mantegani,
- S Cavanus,
- M G Fornaretto,
- M Buonamici,
- A C Rossi,
- R Roncucci,
- and R G Fariello
FCE 23884, substrate-dependent interaction with the dopaminergic system. II. Preclinical biochemical studies.
J Pharmacol Exp Ther October 1991 259:356-364
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- F Ikomi,
- Y Kawai,
- and T Ohhashi
Beta-1 and beta-2 adrenoceptors mediate smooth muscle relaxation in bovine isolated mesenteric lymphatics.
J Pharmacol Exp Ther October 1991 259:365-370
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- T Ohrui,
- K Sekizawa,
- K Yamauchi,
- Y Ohkawara,
- H Nakazawa,
- T Aikawa,
- H Sasaki,
- and T Takishima
Chemical oxidant potentiates electrically and acetylcholine-induced contraction in rat trachea: possible involvement of cholinesterase inhibition.
J Pharmacol Exp Ther October 1991 259:371-376
- Abstract
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- K L Swanson,
- R S Aronstam,
- S Wonnacott,
- H Rapoport,
- and E X Albuquerque
Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites.
J Pharmacol Exp Ther October 1991 259:377-386
- Abstract
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- S Wonnacott,
- S Jackman,
- K L Swanson,
- H Rapoport,
- and E X Albuquerque
Nicotinic pharmacology of anatoxin analogs. II. Side chain structure-activity relationships at neuronal nicotinic ligand binding sites.
J Pharmacol Exp Ther October 1991 259:387-391
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- M J Marks,
- S M Campbell,
- E Romm,
- and A C Collins
Genotype influences the development of tolerance to nicotine in the mouse.
J Pharmacol Exp Ther October 1991 259:392-402
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- F J Carmichael,
- Y Israel,
- M Crawford,
- K Minhas,
- V Saldivia,
- S Sandrin,
- P Campisi,
- and H Orrego
Central nervous system effects of acetate: contribution to the central effects of ethanol.
J Pharmacol Exp Ther October 1991 259:403-408
- Abstract
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- B Gomez-Mancilla and
- P J Bédard
Effect of D1 and D2 agonists and antagonists on dyskinesia produced by L-dopa in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.
J Pharmacol Exp Ther October 1991 259:409-413
- Abstract
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- R Zini,
- D Morin,
- P Martin,
- A J Puech,
- and J P Tillement
Interactions of flerobuterol, an antidepressant drug candidate, with beta adrenoceptors in the rat brain.
J Pharmacol Exp Ther October 1991 259:414-422
- Abstract
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- K J Ivins and
- P B Molinoff
Desensitization and down-regulation of 5-HT2 receptors in P11 cells.
J Pharmacol Exp Ther October 1991 259:423-429
- Abstract
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- D Bleakman,
- P S Chard,
- S Foucart,
- and R J Miller
Block of neuronal Ca++ influx by the anti-ischemic agent TA3090.
J Pharmacol Exp Ther October 1991 259:430-438
- Abstract
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- G Suarez-Kurtz,
- M L Garcia,
- and G J Kaczorowski
Effects of charybdotoxin and iberiotoxin on the spontaneous motility and tonus of different guinea pig smooth muscle tissues.
J Pharmacol Exp Ther October 1991 259:439-443
- Abstract
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- D W Thibeault,
- G Downing,
- N Reddy,
- A J Sonderfan,
- and A Parkinson
Oxygen-induced lung damage in newborn rats, potentiated by 3-methylcholanthrene, a P-450 inducer, and lack of protection by cimetidine, a P-450 inhibitor.
J Pharmacol Exp Ther October 1991 259:444-451
- Abstract
- Full Text (PDF)
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- S D Skaper,
- A Leon,
- and L Facci
Death of cultured hippocampal pyramidal neurons induced by pathological activation of N-methyl-D-aspartate receptors is reduced by monosialogangliosides.
J Pharmacol Exp Ther October 1991 259:452-457
- Abstract
- Full Text (PDF)
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- Z Argov,
- S Nioka,
- S Eleff,
- and B Chance
Effects of intra-arterial epinephrine on energy metabolism in exercising rabbit gastrocnemius muscle, studied by in vivo phosphorus nuclear magnetic resonance.
J Pharmacol Exp Ther October 1991 259:458-463
- Abstract
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- K Grasing and
- H Szeto
Naloxone causes a dose-dependent increase in total power and delta wave activity in the EEG of opioid-naive rats.
J Pharmacol Exp Ther October 1991 259:464-469
- Abstract
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- S G Kim,
- R M Philpot,
- and R F Novak
Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: characterization of high- and low-affinity pyridine N-oxygenases.
J Pharmacol Exp Ther October 1991 259:470-477
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Platelet-activating factor induces nonspecific desensitization to bronchodilators in guinea pigs.

Antithrombotic and anticoagulant properties of synthetic polyanions: sulfated bis-aldonic acid amides.

Pharmacologic profile of (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H- benzimidazole hydrochloride (YM060), a potent and selective 5-hydroxytryptamine3 receptor antagonist, and its enantiomer in the isolated tissue.

Sigma receptor ligands inhibit rat tail artery contractile responses by multiple mechanisms.

Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine.

Differential inhibition of neuropeptide Y on the chronotropic and inotropic responses to sympathetic and parasympathetic stimulation in the isolated, perfused dog atrium.

Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.

NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.

Evidence that the serotonin agonist, DOI, increases renin secretion and blood pressure through both central and peripheral 5-HT2 receptors.

Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo.

Role of endothelium in responses of isolated hepatic vessels to vasoactive agents.

Pharmacology of a potent platelet-activating factor antagonist: Ro 24-4736.

Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques.

Effect of potassium channel blockade on the anti-ischemic actions of mechanistically diverse agents.

Functional interactions between capsaicin-sensitive and cholinergic nerves in the guinea pig bronchus.

Depolarizing agents induce oscillations in canine bronchial smooth muscle membrane potential: possible mechanisms.

Glucagon pharmacodynamics and modulation of sympathetic nerve and norepinephrine-induced constrictor responses in the superior mesenteric artery of the cat.

Characterization of monoaminergic receptors in hypothalamic nuclei mediating feeding behavior in rats.

Sympathetic activation by chronic insulin treatment in conscious rats.

An in vitro evaluation of metabolism and poor membrane permeation impeding intestinal absorption of leucine enkephalin, and methods to increase absorption.

Binding of the novel ligand [4,5-3H-Leu10]substance P to high-affinity NK-1 receptors on guinea pig lung membranes: modulation by GTP analogs and sulfhydryl modifying agents.

Dehydroabietic acid, a major anionic contaminant of pulp mill effluent, reduces both active p-aminohippurate transport and passive membrane permeability in isolated renal membranes.

Guanine nucleotide-binding proteins modulate desmethoxyverapamil binding to calcium channels in vascular smooth muscle.

Anti-inflammatory activity of pergolide, a dopamine receptor agonist.

Age-related changes in vascular sympathetic neurotransmission in the rat kidney.

On the mechanism of the positive inotropy of low concentrations of strophanthidin.

Pharmacological profile of UP 5145-52, an original antiulcer and antisecretory agent.

Inhibition of airway smooth muscle tone by a phorbol ester in the guinea pig trachea: role of epithelium and receptor reserve of the contractile agent.

Differential effects of substance P analogs on neurokinin 1 receptor agonists in the mouse spinal cord.

Mechanisms of ionophore-induced stimulation of renin secretion with special reference to a chemiosmotic hypothesis.

Inhibition of thromboxane synthetase potentiates the antihypertensive action of an angiotensin-converting enzyme inhibitor by a prostaglandin-dependent but kinin-independent mechanism.

Mechanism for homologous downregulation of thromboxane A2 receptors in cultured human chronic myelogenous leukemia (K562) cells.

Modulation of gamma-aminobutyric acid receptor-channel complex by alcohols.

Cocaine and tracheal epithelial function: effects on short circuit current and neurotransmitter receptors.

Behavioral effects of U-78875, a quinoxalinone anxiolytic with potent benzodiazepine antagonist activity.

Reduced G protein function in desensitized rat aorta.

Nitric oxide synthase inhibitors inhibit interleukin-1 beta-induced depression of vascular smooth muscle.

Effects of bradykinin and bradykinin analogs on the opossum lower esophageal sphincter: characterization of an inhibitory bradykinin receptor.

Effect of morphine administration on rat liver metallothionein and zinc metabolism.

Membrane-mediated effects of the steroid 17-alpha-estradiol on adrenal catecholamine release.

Behavioral effects of A1- and A2-selective adenosine agonists and antagonists: evidence for synergism and antagonism.

Involvement of mu, delta and kappa receptors in morphine-induced tolerance in the guinea pig myenteric plexus.

Up-regulation of delta opioid receptors in neuroblastoma hybrid cells: evidence for differences in the mechanisms of action of sodium butyrate and naltrexone.

Characterization of endothelium-derived relaxing factor/nitric oxide synthase from bovine cerebellum and mechanism of modulation by high and low oxygen tensions.

In vivo interactions between beta-1 and beta-2 adrenoceptors regulate catecholamine tachyphylaxia in human adipose tissue.

Characterization of the alpha-2C adrenergic receptor subtype in the opossum kidney and in the OK cell line.

Involvement of epsilon and kappa opioid receptors in inhibition of the tail-flick response induced by bremazocine in the mouse.

Inhibition of binding of [3H]PN200-110 to membranes from rat brain and heart by ascorbate is mediated by lipid peroxidation.

FCE 23884, substrate-dependent interaction with the dopaminergic system. I. Preclinical behavioral studies.

FCE 23884, substrate-dependent interaction with the dopaminergic system. II. Preclinical biochemical studies.

Beta-1 and beta-2 adrenoceptors mediate smooth muscle relaxation in bovine isolated mesenteric lymphatics.

Chemical oxidant potentiates electrically and acetylcholine-induced contraction in rat trachea: possible involvement of cholinesterase inhibition.

Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites.

Nicotinic pharmacology of anatoxin analogs. II. Side chain structure-activity relationships at neuronal nicotinic ligand binding sites.

Genotype influences the development of tolerance to nicotine in the mouse.

Central nervous system effects of acetate: contribution to the central effects of ethanol.

Effect of D1 and D2 agonists and antagonists on dyskinesia produced by L-dopa in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkeys.

Interactions of flerobuterol, an antidepressant drug candidate, with beta adrenoceptors in the rat brain.

Desensitization and down-regulation of 5-HT2 receptors in P11 cells.

Block of neuronal Ca++ influx by the anti-ischemic agent TA3090.

Effects of charybdotoxin and iberiotoxin on the spontaneous motility and tonus of different guinea pig smooth muscle tissues.

Oxygen-induced lung damage in newborn rats, potentiated by 3-methylcholanthrene, a P-450 inducer, and lack of protection by cimetidine, a P-450 inhibitor.

Death of cultured hippocampal pyramidal neurons induced by pathological activation of N-methyl-D-aspartate receptors is reduced by monosialogangliosides.

Effects of intra-arterial epinephrine on energy metabolism in exercising rabbit gastrocnemius muscle, studied by in vivo phosphorus nuclear magnetic resonance.

Naloxone causes a dose-dependent increase in total power and delta wave activity in the EEG of opioid-naive rats.

Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: characterization of high- and low-affinity pyridine N-oxygenases.

This Issue

Current Issue