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Table of Contents
April 1991; 257 (1)
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D Paul
,
C G Pick
,
L A Tive
,
and
G W Pasternak
Pharmacological characterization of nalorphine, a kappa 3 analgesic.
J Pharmacol Exp Ther
April 1991
257
:
1
-
7
Abstract
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A H Oliveto
,
M J Picker
,
and
L A Dykstra
Acute and chronic morphine administration: effects of mixed-action opioids in rats and squirrel monkeys responding under a schedule of food presentation.
J Pharmacol Exp Ther
April 1991
257
:
8
-
18
Abstract
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E Agneter
,
H Drobny
,
and
E A Singer
Estimation of agonist dissociation constants at central presynaptic alpha-2 autoreceptors in the absence of autoinhibition.
J Pharmacol Exp Ther
April 1991
257
:
19
-
25
Abstract
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C K Buckner
,
D Dea
,
N Liberati
,
and
R D Krell
A pharmacologic examination of receptors mediating serotonin-induced bronchoconstriction in the anesthetized guinea pig.
J Pharmacol Exp Ther
April 1991
257
:
26
-
34
Abstract
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L Farraway
and
J D Huizinga
Potassium channel activation by cromakalim affects the slow wave type action potential of colonic smooth muscle.
J Pharmacol Exp Ther
April 1991
257
:
35
-
41
Abstract
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R D McQuade
,
R A Duffy
,
V L Coffin
,
R E Chipkin
,
and
A Barnett
In vivo binding of SCH 39166: a D-1 selective antagonist.
J Pharmacol Exp Ther
April 1991
257
:
42
-
49
Abstract
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K H Park
and
J P Long
Modulation by physostigmine of head-up tilt- and bilateral carotid occlusion-induced baroreflexes in rats.
J Pharmacol Exp Ther
April 1991
257
:
50
-
55
Abstract
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J T Eells
Methanol-induced visual toxicity in the rat.
J Pharmacol Exp Ther
April 1991
257
:
56
-
63
Abstract
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Z Yu
and
J H McNeill
Altered inotropic responses in diabetic cardiomyopathy and hypertensive-diabetic cardiomyopathy.
J Pharmacol Exp Ther
April 1991
257
:
64
-
71
Abstract
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N L Ostrowski
and
A R Caggiula
Correlation between locomotor stimulation and the electrophysiological effects of low doses of morphine on substantia nigra dopamine neurons. I. Acute drug administration.
J Pharmacol Exp Ther
April 1991
257
:
72
-
81
Abstract
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M Kobayashi
,
H Nakamura
,
J Kobayashi
,
and
Y Ohizumi
Mechanism of inotropic action of xestoquinone, a novel cardiotonic agent isolated from a sea sponge.
J Pharmacol Exp Ther
April 1991
257
:
82
-
89
Abstract
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M Kobayashi
,
A Muroyama
,
H Nakamura
,
J Kobayashi
,
and
Y Ohizumi
Xestoquinone, a novel cardiotonic agent activates actomyosin ATPase to enhance contractility of skinned cardiac or skeletal muscle fibers.
J Pharmacol Exp Ther
April 1991
257
:
90
-
94
Abstract
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J A Saydoff
,
P A Rittenhouse
,
L D van de Kar
,
and
M S Brownfield
Enhanced serotonergic transmission stimulates oxytocin secretion in conscious male rats.
J Pharmacol Exp Ther
April 1991
257
:
95
-
99
Abstract
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R A Yokel
,
A K Datta
,
and
E G Jackson
Evaluation of potential aluminum chelators in vitro by aluminum solubilization ability, aluminum mobilization from transferrin and the octanol/aqueous distribution of the chelators and their complexes with aluminum.
J Pharmacol Exp Ther
April 1991
257
:
100
-
106
Abstract
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O Matusak
,
O Kuchel
,
and
P Hamet
Effect of atrial natriuretic factor and 8-bromo cyclic guanosine 3':5'-monophosphate on [3H]acetylcholine outflow from myenteric-plexus longitudinal muscle of the guinea pig.
J Pharmacol Exp Ther
April 1991
257
:
107
-
113
Abstract
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E Ongini
,
S Milani
,
M Marzanatti
,
M Trampus
,
and
A Monopoli
Effects of selected beta-adrenergic blocking agents on sleep stages in spontaneously hypertensive rats.
J Pharmacol Exp Ther
April 1991
257
:
114
-
119
Abstract
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E T Iwamoto
Characterization of the antinociception induced by nicotine in the pedunculopontine tegmental nucleus and the nucleus raphe magnus.
J Pharmacol Exp Ther
April 1991
257
:
120
-
133
Abstract
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L A Merkel
,
L M Rivera
,
D J Colussi
,
and
M H Perrone
Protein kinase C and vascular smooth muscle contractility: effects of inhibitors and down-regulation.
J Pharmacol Exp Ther
April 1991
257
:
134
-
140
Abstract
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Y Itzhak
,
I Stein
,
S H Zhang
,
C O Kassim
,
and
D Cristante
Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes.
J Pharmacol Exp Ther
April 1991
257
:
141
-
148
Abstract
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D A Griffiths
,
S D Hall
,
and
P P Sokol
Interaction of 3'-azido-3'-deoxythymidine with organic ion transport in rat renal basolateral membrane vesicles.
J Pharmacol Exp Ther
April 1991
257
:
149
-
155
Abstract
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G J Grover
,
J Newburger
,
P G Sleph
,
S Dzwonczyk
,
S C Taylor
,
S Z Ahmed
,
and
K S Atwal
Cardioprotective effects of the potassium channel opener cromakalim: stereoselectivity and effects on myocardial adenine nucleotides.
J Pharmacol Exp Ther
April 1991
257
:
156
-
162
Abstract
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C P Cheng
,
Y Igarashi
,
K Pettersson
,
and
W C Little
Effect of felodipine on left ventricular performance in conscious dogs: assessment by left ventricular pressure-volume analysis.
J Pharmacol Exp Ther
April 1991
257
:
163
-
169
Abstract
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M Pacheco
,
S R Childers
,
R Arnold
,
F Casiano
,
and
S J Ward
Aminoalkylindoles: actions on specific G-protein-linked receptors.
J Pharmacol Exp Ther
April 1991
257
:
170
-
183
Abstract
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J J Pancrazio
,
M P Viglione
,
R J Kleiman
,
and
Y I Kim
Verapamil-induced blockade of voltage-activated K+ current in small-cell lung cancer cells.
J Pharmacol Exp Ther
April 1991
257
:
184
-
191
Abstract
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L S Sorkin
,
M G Hughes
,
D Liu
,
W D Willis, Jr
,
and
D J McAdoo
Release and metabolism of 5-hydroxytryptamine in the cat spinal cord examined with microdialysis.
J Pharmacol Exp Ther
April 1991
257
:
192
-
199
Abstract
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A Takayama
,
Y Okazaki
,
K Fukuda
,
M Takano
,
K Inui
,
and
R Hori
Transport of cyclosporin A in kidney epithelial cell line (LLC-PK1).
J Pharmacol Exp Ther
April 1991
257
:
200
-
204
Abstract
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L E Brackett
and
J W Daly
Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms.
J Pharmacol Exp Ther
April 1991
257
:
205
-
213
Abstract
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G Bittar
,
H S Friedman
,
A Dominguez
,
and
V Vorperian
Theophylline produces an adverse effect on myocardial lactate metabolism at a therapeutic serum concentration: an effect blocked by verapamil.
J Pharmacol Exp Ther
April 1991
257
:
214
-
218
Abstract
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C S Park
,
P S Doh
,
C J Lee
,
D S Han
,
R E Carraway
,
and
T B Miller
Cellular mechanism of stimulation of renin secretion by the mercurial diuretic mersalyl.
J Pharmacol Exp Ther
April 1991
257
:
219
-
224
Abstract
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P E Simson
,
H E Criswell
,
K B Johnson
,
R E Hicks
,
and
G R Breese
Ethanol inhibits NMDA-evoked electrophysiological activity in vivo.
J Pharmacol Exp Ther
April 1991
257
:
225
-
231
Abstract
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D Ratge
,
K P Kohse
,
U Steegmüller
,
and
H Wisser
Distribution of free and conjugated catecholamines between plasma, platelets and erythrocytes: different effects of intravenous and oral catecholamine administrations.
J Pharmacol Exp Ther
April 1991
257
:
232
-
238
Abstract
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S M Johnson
Nonspecific tolerance in ileal circular muscle-myenteric plexus preparations from morphine-pretreated guinea pigs.
J Pharmacol Exp Ther
April 1991
257
:
239
-
246
Abstract
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R W Foltin
and
M W Fischman
Smoked and intravenous cocaine in humans: acute tolerance, cardiovascular and subjective effects.
J Pharmacol Exp Ther
April 1991
257
:
247
-
261
Abstract
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J F Bowyer
,
A C Scallet
,
R R Holson
,
G W Lipe
,
W Slikker, Jr
,
and
S F Ali
Interactions of MK-801 with glutamate-, glutamine- and methamphetamine-evoked release of [3H]dopamine from striatal slices.
J Pharmacol Exp Ther
April 1991
257
:
262
-
270
Abstract
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T Nabeshima
,
K Tohyama
,
K Murase
,
S Ishihara
,
T Kameyama
,
T Yamasaki
,
S Hatanaka
,
H Kojima
,
T Sakurai
,
and
Y Takasu
Effects of DM-9384, a cyclic derivative of GABA, on amnesia and decreases in GABAA and muscarinic receptors induced by cycloheximide.
J Pharmacol Exp Ther
April 1991
257
:
271
-
275
Abstract
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R Andriantsitohaina
,
J C Stoclet
,
and
R D Bukoski
Role of endothelium on the effects of neuropeptide Y in mesenteric resistance arteries of spontaneously hypertensive and Wistar-Kyoto normotensive rats.
J Pharmacol Exp Ther
April 1991
257
:
276
-
281
Abstract
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M B Abou-Donia
,
Z H Hu
,
D M Lapadula
,
and
R P Gupta
Mechanisms of joint neurotoxicity of n-hexane, methyl isobutyl ketone and O-ethyl O-4-nitrophenyl phenylphosphonothioate in hens.
J Pharmacol Exp Ther
April 1991
257
:
282
-
289
Abstract
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V M Miller
,
N A Flavahan
,
and
P M Vanhoutte
Pertussis toxin reduces endothelium-dependent and independent responses to alpha-2- adrenergic stimulation in systemic canine arteries and veins.
J Pharmacol Exp Ther
April 1991
257
:
290
-
293
Abstract
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K S Pang
,
F Barker, 3rd
,
W F Cherry
,
and
C A Goresky
Esterases for enalapril hydrolysis are concentrated in the perihepatic venous region of the rat liver.
J Pharmacol Exp Ther
April 1991
257
:
294
-
301
Abstract
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J L Banasik
,
H Hosick
,
J W Wright
,
and
J W Harding
Endothelin binding in brain of normotensive and spontaneously hypertensive rats.
J Pharmacol Exp Ther
April 1991
257
:
302
-
306
Abstract
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J P Boni
,
W H Barr
,
and
B R Martin
Cocaine inhalation in the rat: pharmacokinetics and cardiovascular response.
J Pharmacol Exp Ther
April 1991
257
:
307
-
315
Abstract
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M R Bleavins
,
F A de la Iglesia
,
A E Munson
,
J A McCay
,
M L Stern
,
B A Fuchs
,
and
K L White, Jr
Effects of CI-949, a novel antiallergy agent, on immune function of male Fischer 344 rats.
J Pharmacol Exp Ther
April 1991
257
:
316
-
322
Abstract
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K Y Sheff
,
M A Yorek
,
and
J P Long
Hemicholinium-3 derivatives A-4 and A-5 alter choline metabolism in NB41A3 neuroblastoma cells.
J Pharmacol Exp Ther
April 1991
257
:
323
-
330
Abstract
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P Porta
,
S Aebi
,
K Summer
,
and
B H Lauterburg
L-2-oxothiazolidine-4-carboxylic acid, a cysteine prodrug: pharmacokinetics and effects on thiols in plasma and lymphocytes in human.
J Pharmacol Exp Ther
April 1991
257
:
331
-
334
Abstract
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C W Murray
and
A Cowan
Tonic pain perception in the mouse: differential modulation by three receptor-selective opioid agonists.
J Pharmacol Exp Ther
April 1991
257
:
335
-
341
Abstract
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N A Castle
Selective inhibition of potassium currents in rat ventricle by clofilium and its tertiary homolog.
J Pharmacol Exp Ther
April 1991
257
:
342
-
350
Abstract
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X Z Wu
,
J A Bell
,
C E Spivak
,
E D London
,
and
T P Su
Electrophysiological and binding studies on intact NCB-20 cells suggest presence of a low affinity sigma receptor.
J Pharmacol Exp Ther
April 1991
257
:
351
-
359
Abstract
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S Aran
and
D L Hammond
Antagonism of baclofen-induced antinociception by intrathecal administration of phaclofen or 2-hydroxy-saclofen, but not delta-aminovaleric acid in the rat.
J Pharmacol Exp Ther
April 1991
257
:
360
-
368
Abstract
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T Shimamura
,
T Kimura
,
and
S Satoh
Effects of pirenzepine, AF-DX 116 and gallamine on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation: interaction of M1 and M2 receptors with nicotinic receptors.
J Pharmacol Exp Ther
April 1991
257
:
369
-
373
Abstract
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T L Yue
,
M M Gleason
,
J L Gu
,
P G Lysko
,
J Hallenbeck
,
and
G Feuerstein
Platelet-activating factor (PAF) receptor-mediated calcium mobilization and phosphoinositide turnover in neurohybrid NG108-15 cells: studies with BN50739, a new PAF antagonist.
J Pharmacol Exp Ther
April 1991
257
:
374
-
381
Abstract
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P J Silver
,
B O'Connor
,
W R Cumiskey
,
G Van Aller
,
L T Hamel
,
R G Bentley
,
and
E D Pagani
Inhibition of low Km cGMP phosphodiesterases and Ca+(+)-regulated protein kinases and relationship to vasorelaxation by cicletanine.
J Pharmacol Exp Ther
April 1991
257
:
382
-
391
Abstract
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A Fisher
,
R Brandeis
,
I Karton
,
Z Pittel
,
D Gurwitz
,
R Haring
,
M Sapir
,
A Levy
,
and
E Heldman
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease.
J Pharmacol Exp Ther
April 1991
257
:
392
-
403
Abstract
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S Takeo
,
R Tanonaka
,
K Miyake
,
K Tanonaka
,
T Taguchi
,
K Kawakami
,
M Ono
,
M Hiramatsu
,
and
K Okano
Naftidrofuryl oxalate improves impaired brain glucose metabolism after microsphere-induced cerebral embolism in rats.
J Pharmacol Exp Ther
April 1991
257
:
404
-
410
Abstract
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D R Abernethy
,
L S Kaminsky
,
and
T H Dickinson
Selective inhibition of warfarin metabolism by diltiazem in humans.
J Pharmacol Exp Ther
April 1991
257
:
411
-
415
Abstract
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R R Ben-Harari
,
B A Dalton
,
R Osman
,
and
S Maayani
Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta.
J Pharmacol Exp Ther
April 1991
257
:
416
-
424
Abstract
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A Dedeoğlu
and
L A Fisher
Central nervous actions of serotonin and a serotonin1A receptor agonist: cardiovascular excitation at low doses.
J Pharmacol Exp Ther
April 1991
257
:
425
-
432
Abstract
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A Varrault
,
V Leviel
,
and
J Bockaert
5-HT1A-sensitive adenylyl cyclase of rodent hippocampal neurons: effects of antidepressant treatments and chronic stimulation with agonists.
J Pharmacol Exp Ther
April 1991
257
:
433
-
438
Abstract
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G Bravo
,
J Ghysel-Burton
,
P Jaumin
,
and
T Godfraind
A comparison of the inotropic effects of dopamine and epinine in human isolated cardiac preparations.
J Pharmacol Exp Ther
April 1991
257
:
439
-
443
Abstract
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C E Lau
,
A Imam
,
F Ma
,
and
J L Falk
Acute effects of cocaine on spontaneous and discriminative motor functions: relation to route of administration and pharmacokinetics.
J Pharmacol Exp Ther
April 1991
257
:
444
-
456
Abstract
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J L Falk
,
F Ma
,
and
C E Lau
Chronic oral cocaine self-administration: pharmacokinetics and effects on spontaneous and discriminative motor functions.
J Pharmacol Exp Ther
April 1991
257
:
457
-
465
Abstract
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A Ezzaher
,
N el Houda Bouanani
,
J B Su
,
L Hittinger
,
and
B Crozatier
Increased negative inotropic effect of calcium-channel blockers in hypertrophied and failing rabbit heart.
J Pharmacol Exp Ther
April 1991
257
:
466
-
471
Abstract
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J W Mandema
,
L N Sansom
,
M C Dios-Vièitez
,
M Hollander-Jansen
,
and
M Danhof
Pharmacokinetic-pharmacodynamic modeling of the electroencephalographic effects of benzodiazepines. Correlation with receptor binding and anticonvulsant activity.
J Pharmacol Exp Ther
April 1991
257
:
472
-
478
Abstract
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A E Ahmed
,
S Jacob
,
J P Loh
,
S K Samra
,
M Nokta
,
and
R B Pollard
Comparative disposition and whole-body autoradiographic distribution of [2-14C]azidothymidine and [2-14C]thymidine in mice.
J Pharmacol Exp Ther
April 1991
257
:
479
-
486
Abstract
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D M Kerins
,
M Shuh
,
S Kunitada
,
G A Fitzgerald
,
and
D J Fitzgerald
A prostacyclin analog impairs the response to tissue-type plasminogen activator during coronary thrombolysis: evidence for a pharmacokinetic interaction.
J Pharmacol Exp Ther
April 1991
257
:
487
-
492
Abstract
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M Soose
,
W Gwinner
,
J Grotkamp
,
W Hansemann
,
and
H Stolte
Altered renal fibronectin excretion in early adriamycin nephrosis of rats.
J Pharmacol Exp Ther
April 1991
257
:
493
-
499
Abstract
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H A Pretus
,
H E Ensley
,
R B McNamee
,
E L Jones
,
I W Browder
,
and
D L Williams
Isolation, physicochemical characterization and preclinical efficacy evaluation of soluble scleroglucan.
J Pharmacol Exp Ther
April 1991
257
:
500
-
510
Abstract
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V F Raczkowski
,
Y M Hernandez
,
H K Erzouki
,
T P Abrahams
,
A K Mandal
,
P Hamosh
,
E Friedman
,
J A Quest
,
K L Dretchen
,
and
R A Gillis
Cocaine acts in the central nervous system to inhibit sympathetic neural activity.
J Pharmacol Exp Ther
April 1991
257
:
511
-
519
Abstract
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A Terzic
and
S M Vogel
On the mechanism of the positive inotropic action of the alpha adrenoceptor agonist, phenylephrine, in isolated rat left atria.
J Pharmacol Exp Ther
April 1991
257
:
520
-
529
Abstract
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L F Tseng
and
K A Collins
Different mechanisms mediating tail-flick inhibition induced by beta-endorphin, DAMGO and morphine from ROb and GiA in anesthetized rats.
J Pharmacol Exp Ther
April 1991
257
:
530
-
538
Abstract
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Article
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ERRATUM
J Pharmacol Exp Ther
April 1991
257
:
539
Abstract
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April 1991; 257 (1)
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