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Table of Contents
February 1991; 256 (2)
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J G Granneman
and
C J Whitty
CGP 12177A modulates brown fat adenylate cyclase activity by interacting with two distinct receptor sites.
J Pharmacol Exp Ther
February 1991
256
:
421
-
425
Abstract
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G L Kamatchi
and
M K Ticku
A functional assay to measure postsynaptic gamma-aminobutyric acidB responses in cultured spinal cord neurons: heterologous regulation of the same K+ channel.
J Pharmacol Exp Ther
February 1991
256
:
426
-
431
Abstract
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W Löscher
and
D Hönack
Anticonvulsant and behavioral effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine.
J Pharmacol Exp Ther
February 1991
256
:
432
-
440
Abstract
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G E Boeckxstaens
,
P A Pelckmans
,
J J Bogers
,
H Bult
,
J G De Man
,
L Oosterbosch
,
A G Herman
,
and
Y M Van Maercke
Release of nitric oxide upon stimulation of nonadrenergic noncholinergic nerves in the rat gastric fundus.
J Pharmacol Exp Ther
February 1991
256
:
441
-
447
Abstract
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J J Rady
,
S C Roerig
,
and
J M Fujimoto
Heroin acts on different opioid receptors than morphine in Swiss Webster and ICR mice to produce antinociception.
J Pharmacol Exp Ther
February 1991
256
:
448
-
457
Abstract
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M Polhuijs
,
D K Meijer
,
and
G J Mulder
The fate of diastereomeric glutathione conjugates of alpha-bromoisovalerylurea in blood in the rat in vivo and in the perfused liver. Stereoselectivity in biliary and urinary excretion.
J Pharmacol Exp Ther
February 1991
256
:
458
-
461
Abstract
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D J Hupe
,
E R Pfefferkorn
,
N D Behrens
,
and
K Peters
L-651,582 inhibition of intracellular parasitic protozoal growth correlates with host-cell directed effects.
J Pharmacol Exp Ther
February 1991
256
:
462
-
467
Abstract
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N H Lee
and
E E el-Fakahany
Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes.
J Pharmacol Exp Ther
February 1991
256
:
468
-
479
Abstract
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D Raeburn
and
T J Brown
RP 49356 and cromakalim relax airway smooth muscle in vitro by opening a sulphonylurea-sensitive K+ channel: a comparison with nifedipine.
J Pharmacol Exp Ther
February 1991
256
:
480
-
485
Abstract
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C J Chen
,
S Apparsundaram
,
and
M F Lokhandwala
Intrarenally produced angiotensin II opposes the natriuretic action of the dopamine-1 receptor agonist fenoldopam in rats.
J Pharmacol Exp Ther
February 1991
256
:
486
-
491
Abstract
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K D Meisheri
,
M A Swirtz
,
S S Purohit
,
L A Cipkus-Dubray
,
S A Khan
,
and
J J Oleynek
Characterization of K+ channel-dependent as well as -independent components of pinacidil-induced vasodilation.
J Pharmacol Exp Ther
February 1991
256
:
492
-
499
Abstract
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J Manzanares
,
K J Lookingland
,
and
K E Moore
Kappa opioid receptor-mediated regulation of dopaminergic neurons in the rat brain.
J Pharmacol Exp Ther
February 1991
256
:
500
-
505
Abstract
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P K Sonsalla
,
D E Riordan
,
and
R E Heikkila
Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.
J Pharmacol Exp Ther
February 1991
256
:
506
-
512
Abstract
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S P Duckles
Reserpine-induced supersensitivity in rat caudal artery: influence of age.
J Pharmacol Exp Ther
February 1991
256
:
513
-
518
Abstract
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T Massamiri
and
S P Duckles
Interactions of sigma and phencyclidine receptor ligands with the norepinephrine uptake carrier in both rat brain and rat tail artery.
J Pharmacol Exp Ther
February 1991
256
:
519
-
524
Abstract
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O Mukaiyama
,
A Takeuchi
,
T Kimura
,
and
S Satoh
Effects of pirenzepine and AF-DX 116 on ganglionic transmission in the cardiac sympathetic nerves of the dog: interaction of M1 and M2 receptors with nicotinic receptors.
J Pharmacol Exp Ther
February 1991
256
:
525
-
529
Abstract
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N R Swerdlow
,
V A Keith
,
D L Braff
,
and
M A Geyer
Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat.
J Pharmacol Exp Ther
February 1991
256
:
530
-
536
Abstract
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K F Heim
,
G Thomas
,
and
P W Ramwell
Superoxide production in the isolated rabbit aorta and the effect of alloxan, indomethacin and nitrovasodilators.
J Pharmacol Exp Ther
February 1991
256
:
537
-
541
Abstract
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A S Nies
,
M L Beckmann
,
and
J G Gerber
Contrasting effects of changes in salt balance on the renovascular response to A1-adenosine receptor stimulation in vivo and in vitro in the rat.
J Pharmacol Exp Ther
February 1991
256
:
542
-
546
Abstract
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P J Rivière
,
S C Farmer
,
T F Burks
,
and
F Porreca
Prostaglandin E2-induced diarrhea in mice: importance of colonic secretion.
J Pharmacol Exp Ther
February 1991
256
:
547
-
552
Abstract
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G J Christ
and
M Jean-Jacques
Mutual-effect amplification of contractile responses elicited by simultaneous activation of alpha-1 adrenergic and 5-hydroxytryptamine2 receptors in isolated rat aorta.
J Pharmacol Exp Ther
February 1991
256
:
553
-
561
Abstract
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L Noronha-Blob
and
J F Kachur
Enantiomers of oxybutynin: in vitro pharmacological characterization at M1, M2 and M3 muscarinic receptors and in vivo effects on urinary bladder contraction, mydriasis and salivary secretion in guinea pigs.
J Pharmacol Exp Ther
February 1991
256
:
562
-
567
Abstract
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R E Weishaar
,
R L Panek
,
T C Major
,
J Simmerman
,
S T Rapundalo
,
and
D G Taylor, Jr
Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure.
J Pharmacol Exp Ther
February 1991
256
:
568
-
574
Abstract
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K Lutfy
and
B C Yoburn
The role of opioid receptor density in morphine tolerance.
J Pharmacol Exp Ther
February 1991
256
:
575
-
580
Abstract
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E Baldi
and
M J Dunn
Endothelin binding and receptor down regulation in rat glomerular mesangial cells.
J Pharmacol Exp Ther
February 1991
256
:
581
-
586
Abstract
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P A Johnston
and
S T Kau
Micropuncture evaluation of the site of action of 2-aminomethyl-4-(1,1-dimethylethyl)-6-iodophenol hydrochloride (MK447) in the rat kidney.
J Pharmacol Exp Ther
February 1991
256
:
587
-
591
Abstract
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J Hauser
and
S Szabo
Extremely long protection by pyrazole derivatives against chemically induced gastric mucosal injury.
J Pharmacol Exp Ther
February 1991
256
:
592
-
598
Abstract
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R N Willette
,
J P Hieble
,
and
C F Sauermelch
The role of alpha adrenoceptor subtypes in sympathetic control of the acral-cutaneous microcirculation.
J Pharmacol Exp Ther
February 1991
256
:
599
-
605
Abstract
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E Tibiriça
,
J Feldman
,
C Mermet
,
F Gonon
,
and
P Bousquet
An imidazoline-specific mechanism for the hypotensive effect of clonidine: a study with yohimbine and idazoxan.
J Pharmacol Exp Ther
February 1991
256
:
606
-
613
Abstract
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R G Pendleton
,
G Gessner
,
and
E Horner
Comparative effects of angiotensin II and angiotensin III in rabbit adrenal and aortic tissues.
J Pharmacol Exp Ther
February 1991
256
:
614
-
620
Abstract
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J W Hubbard
,
P G Conway
,
L C Nordstrom
,
H B Hartman
,
Y Lebedinsky
,
G J O'Malley
,
and
R W Kosley, Jr
Cardiac adenylate cyclase activity, positive chronotropic and inotropic effects of forskolin analogs with either low, medium or high binding site affinity.
J Pharmacol Exp Ther
February 1991
256
:
621
-
627
Abstract
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L C Wilkes
and
M R Boarder
Characterization of the endothelin binding site on bovine adrenomedullary chromaffin cells: comparison with vascular smooth muscle cells. Evidence for receptor heterogeneity.
J Pharmacol Exp Ther
February 1991
256
:
628
-
633
Abstract
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Y Kamisaki
,
T Hamahashi
,
C Mita
,
and
T Itoh
D-2 dopamine receptors inhibit release of aspartate and glutamate in rat retina.
J Pharmacol Exp Ther
February 1991
256
:
634
-
638
Abstract
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N J Lodge
,
R B Cohen
,
C N Havens
,
and
T J Colatsky
The effects of the putative potassium channel activator WAY-120,491 on 86Rb efflux from the rabbit aorta.
J Pharmacol Exp Ther
February 1991
256
:
639
-
644
Abstract
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T E Nelson
,
M Lin
,
and
P Volpe
Evidence for intraluminal Ca++ regulatory site defect in sarcoplasmic reticulum from malignant hyperthermia pig muscle.
J Pharmacol Exp Ther
February 1991
256
:
645
-
649
Abstract
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S Shibanoki
,
S B Weinberger
,
D Beniston
,
K A Nudelman
,
G Schulteis
,
E L Bennett
,
M R Rosenzweig
,
K Ishikawa
,
and
J L Martinez, Jr
Hydrolysis of [Leu]enkephalin by chick plasma in vitro.
J Pharmacol Exp Ther
February 1991
256
:
650
-
655
Abstract
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J G Hensler
,
G A Ordway
,
C Gambarana
,
P Areso
,
and
A Frazer
Serotonergic neurons do not influence the regulation of beta adrenoceptors induced by either desipramine or isoproterenol.
J Pharmacol Exp Ther
February 1991
256
:
656
-
664
Abstract
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F A Redegeld
,
G A Hofman
,
P G van de Loo
,
A S Koster
,
and
J Noordhoek
Nephrotoxicity of the glutathione conjugate of menadione (2-methyl-1, 4-naphthoquinone) in the isolated perfused rat kidney. Role of metabolism by gamma-glutamyltranspeptidase and probenecid-sensitive transport.
J Pharmacol Exp Ther
February 1991
256
:
665
-
669
Abstract
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L J Janssen
and
E E Daniel
Classification of postjunctional beta adrenoceptors mediating relaxation of canine bronchi.
J Pharmacol Exp Ther
February 1991
256
:
670
-
676
Abstract
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M Kuhn
,
A Otten
,
J C Frölich
,
and
U Förstermann
Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells.
J Pharmacol Exp Ther
February 1991
256
:
677
-
682
Abstract
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H Shirahase
,
H Usui
,
H Shimaji
,
K Kurahashi
,
and
M Fujiwara
Endothelium-independent and endothelium-dependent contractions mediated by P2X- and P2Y-purinoceptors in canine basilar arteries.
J Pharmacol Exp Ther
February 1991
256
:
683
-
688
Abstract
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L Mei
,
J Lai
,
H I Yamamura
,
and
W R Roeske
Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82).
J Pharmacol Exp Ther
February 1991
256
:
689
-
694
Abstract
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V L Lucaites
,
L G Mendelsohn
,
N R Mason
,
and
M L Cohen
CCK-8, CCK-4 and gastrin-induced contractions in guinea pig ileum: evidence for differential release of acetylcholine and substance P by CCK-A and CCK-B receptors.
J Pharmacol Exp Ther
February 1991
256
:
695
-
703
Abstract
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J E Shaffer
,
F Lee
,
S Thomson
,
B J Han
,
J P Cooke
,
and
J Loscalzo
The hemodynamic effects of S-nitrosocaptopril in anesthetized dogs.
J Pharmacol Exp Ther
February 1991
256
:
704
-
709
Abstract
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P Y Law
,
D S Hom
,
and
H H Loh
Effect of chronic D-Ala,2 D-Leu5-enkephalin or pertussis toxin treatment on the high-affinity state of delta opioid receptor in neuroblastoma x glioma NG108-15 hybrid cells.
J Pharmacol Exp Ther
February 1991
256
:
710
-
716
Abstract
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P T Peachell
,
L M Lichtenstein
,
and
R P Schleimer
Differential regulation of human basophil and lung mast cell function by adenosine.
J Pharmacol Exp Ther
February 1991
256
:
717
-
726
Abstract
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F Dörje
,
J Wess
,
G Lambrecht
,
R Tacke
,
E Mutschler
,
and
M R Brann
Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
J Pharmacol Exp Ther
February 1991
256
:
727
-
733
Abstract
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J V Frnka
,
A S Chang
,
and
D M Lam
Pharmacological characteristics of high-affinity serotonin uptake systems established through gene transfer.
J Pharmacol Exp Ther
February 1991
256
:
734
-
740
Abstract
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P J Bushnell
,
S S Padilla
,
T Ward
,
C N Pope
,
and
V B Olszyk
Behavioral and neurochemical changes in rats dosed repeatedly with diisopropylfluorophosphate.
J Pharmacol Exp Ther
February 1991
256
:
741
-
750
Abstract
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S X Ma
,
J P Long
,
J R Flynn
,
P A Leonard
,
and
J G Cannon
Dopaminergic structure-activity relationships of 2-aminoindans and cardiovascular action and dopaminergic activity of 4-hydroxy, 5-methyl, 2-di-n-propylaminoindan (RD-211).
J Pharmacol Exp Ther
February 1991
256
:
751
-
756
Abstract
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J B Pracyk
,
S E Lappi
,
and
T A Slotkin
Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney.
J Pharmacol Exp Ther
February 1991
256
:
757
-
766
Abstract
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C Legrand
,
V Vivat
,
C Rigolot
,
and
J P Maltier
Selective distribution of alpha-1 and beta adrenoceptors in pregnant rat uterus visualized by autoradiography.
J Pharmacol Exp Ther
February 1991
256
:
767
-
772
Abstract
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T Kobayashi
,
H Hasegawa
,
E Kaneko
,
and
A Ichiyama
Gastrointestinal serotonin: depletion due to tetrahydrobiopterin deficiency induced by 2,4-diamino-6-hydroxypyrimidine administration.
J Pharmacol Exp Ther
February 1991
256
:
773
-
779
Abstract
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P J Simpson
,
J A Schelm
,
and
G F Smith
Therapeutic defibrination with ancrod does not protect canine myocardium from reperfusion injury.
J Pharmacol Exp Ther
February 1991
256
:
780
-
786
Abstract
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M J Owens
,
D L Knight
,
J C Ritchie
,
and
C B Nemeroff
The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. I. Acute effects on HPA axis activity and corticotropin-releasing factor-containing neurons in the rat brain.
J Pharmacol Exp Ther
February 1991
256
:
787
-
794
Abstract
Full Text (PDF)
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M J Owens
,
D L Knight
,
J C Ritchie
,
and
C B Nemeroff
The 5-hydroxytryptamine2 agonist, (+-)-1-(2,5-dimethoxy-4-bromophenyl)-2-aminopropane stimulates the hypothalamic-pituitary-adrenal (HPA) axis. II. Biochemical and physiological evidence for the development of tolerance after chronic administration.
J Pharmacol Exp Ther
February 1991
256
:
795
-
800
Abstract
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S K Wilson
Peripheral alpha-1 and alpha-2 adrenergic receptors in three models of hypertension in rats: an in vitro autoradiography study.
J Pharmacol Exp Ther
February 1991
256
:
801
-
810
Abstract
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S Subramaniam
and
P McGonigle
Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines.
J Pharmacol Exp Ther
February 1991
256
:
811
-
819
Abstract
Full Text (PDF)
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