Table of Contents

January 1991; 256 (1)

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- R K Zalups,
- R M Gelein,
- and E Cernichiari
DMPS as a rescue agent for the nephropathy induced by mercuric chloride.
J Pharmacol Exp Ther January 1991 256:1-10
- Abstract
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- K Miura,
- T Yukimura,
- Y Yamashita,
- T Shimmen,
- M Okumura,
- S Yamanaka,
- M Imanishi,
- and K Yamamoto
Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins.
J Pharmacol Exp Ther January 1991 256:11-17
- Abstract
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- M Kimura,
- I Kimura,
- T Kondoh,
- and H Tsuneki
Noncontractile acetylcholine receptor-operated Ca++ mobilization: suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle.
J Pharmacol Exp Ther January 1991 256:18-23
- Abstract
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- I Kimura,
- H Tsuneki,
- T Kondoh,
- and M Kimura
Enhancing effect by nicotinic acetylcholine receptor channel blockers, including beta-eudesmol, on succinylcholine-induced inhibition of twitch tension and intracellular Ca++ in mouse diaphragm muscle.
J Pharmacol Exp Ther January 1991 256:24-28
- Abstract
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- K G Mugridge,
- M Perretti,
- C Becherucci,
- and L Parente
Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase.
J Pharmacol Exp Ther January 1991 256:29-37
- Abstract
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- K Ishii,
- B Chang,
- J F Kerwin, Jr,
- F L Wagenaar,
- Z J Huang,
- and F Murad
Formation of endothelium-derived relaxing factor in porcine kidney epithelial LLC-PK1 cells: an intra- and intercellular messenger for activation of soluble guanylate cyclase.
J Pharmacol Exp Ther January 1991 256:38-43
- Abstract
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- L G Harsing, Jr and
- E S Vizi
Evidence that two stereochemically different alpha-2 adrenoceptors modulate norepinephrine release in rat cerebral cortex.
J Pharmacol Exp Ther January 1991 256:44-49
- Abstract
- Full Text (PDF)
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- N A Flavahan,
- H Shimokawa,
- and P M Vanhoutte
Inhibition of endothelium-dependent relaxations by phorbol myristate acetate in canine coronary arteries: role of a pertussis toxin-sensitive G-protein.
J Pharmacol Exp Ther January 1991 256:50-55
- Abstract
- Full Text (PDF)
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- N J Brown,
- J Porter,
- D Ryder,
- and R A Branch
Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine.
J Pharmacol Exp Ther January 1991 256:56-61
- Abstract
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- S G Holtzman,
- S Mante,
- and K P Minneman
Role of adenosine receptors in caffeine tolerance.
J Pharmacol Exp Ther January 1991 256:62-68
- Abstract
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- Y F Huang,
- R N Upton,
- W B Runciman,
- and L E Mather
Insight into interstitial drug disposition: lymph concentrations of lidocaine, procainamide and meperidine in the hindquarters of unanesthetized and anesthetized sheep.
J Pharmacol Exp Ther January 1991 256:69-75
- Abstract
- Full Text (PDF)
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- T Nakazawa,
- Y Furuya,
- T Kaneko,
- and K Yamatsu
Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice.
J Pharmacol Exp Ther January 1991 256:76-81
- Abstract
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- A G Meehan and
- D L Kreulen
Electrophysiological studies on the interaction of 5-hydroxytryptamine with sympathetic transmission in the guinea pig inferior mesenteric artery and ganglion.
J Pharmacol Exp Ther January 1991 256:82-87
- Abstract
- Full Text (PDF)
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- M Raiteri,
- G Bonanno,
- E Fedele,
- G Fontana,
- and A Gemignani
gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex.
J Pharmacol Exp Ther January 1991 256:88-93
- Abstract
- Full Text (PDF)
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- R A Hahn,
- B R MacDonald,
- P J Simpson,
- L Wang,
- R D Towner,
- P P Ho,
- M Goodwin,
- A P Breau,
- T Suarez,
- and E D Mihelich
Characterization of LY233569 on 5-lipoxygenase and reperfusion injury of ischemic myocardium.
J Pharmacol Exp Ther January 1991 256:94-102
- Abstract
- Full Text (PDF)
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- R J Secrest,
- V L Lucaites,
- L G Mendelsohn,
- and M L Cohen
Protein kinase C translocation in rat stomach fundus: effects of serotonin, carbamylcholine and phorbol dibutyrate.
J Pharmacol Exp Ther January 1991 256:103-109
- Abstract
- Full Text (PDF)
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- A Roca-Cusachs,
- D J DiPette,
- and G A Nickols
Regional and systemic hemodynamic effects of parathyroid hormone-related protein: preservation of cardiac function and coronary and renal flow with reduced blood pressure.
J Pharmacol Exp Ther January 1991 256:110-118
- Abstract
- Full Text (PDF)
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- E E Brown,
- J M Finlay,
- J T Wong,
- G Damsma,
- and H C Fibiger
Behavioral and neurochemical interactions between cocaine and buprenorphine: implications for the pharmacotherapy of cocaine abuse.
J Pharmacol Exp Ther January 1991 256:119-126
- Abstract
- Full Text (PDF)
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- A García-Pascual,
- G Costa,
- M Isla,
- E Jimenez,
- and A García-Sacristán
Potassium-induced contraction in the lamb proximal urethra: involvement of norepinephrine and different calcium entry pathways.
J Pharmacol Exp Ther January 1991 256:127-134
- Abstract
- Full Text (PDF)
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- X B Wang,
- N Sato,
- M A Greer,
- S E Greer,
- and S McAdams
Quinidine inhibits prolactin secretion induced by thyrotropin-releasing hormone, high medium potassium or hyposmolarity in GH4C1 cells.
J Pharmacol Exp Ther January 1991 256:135-140
- Abstract
- Full Text (PDF)
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- C C Shieh,
- M F Petrini,
- T M Dwyer,
- and J M Farley
Concentration-dependence of acetylcholine-induced changes in calcium and tension in swine trachealis.
J Pharmacol Exp Ther January 1991 256:141-148
- Abstract
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- S S Negus,
- M J Picker,
- and L A Dykstra
Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey.
J Pharmacol Exp Ther January 1991 256:149-158
- Abstract
- Full Text (PDF)
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- J M Spitsbergen and
- W D Atchison
Voltage clamp analysis reveals multiple populations of quanta released at neuromuscular junctions of rats treated with 2,4-dithiobiuret.
J Pharmacol Exp Ther January 1991 256:159-163
- Abstract
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- F M Lai,
- T Tanikella,
- and P Cervoni
Characterization of serotonin receptors in isolated rat intramyocardial coronary artery.
J Pharmacol Exp Ther January 1991 256:164-168
- Abstract
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- K Takahashi and
- N Akaike
Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons.
J Pharmacol Exp Ther January 1991 256:169-175
- Abstract
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- N A Robinson,
- J G Pace,
- C F Matson,
- G A Miura,
- and W B Lawrence
Tissue distribution, excretion and hepatic biotransformation of microcystin-LR in mice.
J Pharmacol Exp Ther January 1991 256:176-182
- Abstract
- Full Text (PDF)
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- S P Han,
- A J Trapani,
- K F Fok,
- T C Westfall,
- and M M Knuepfer
A comparison of the hemodynamic effects of endothelin-1 and sarafotoxin S6b in conscious rats.
J Pharmacol Exp Ther January 1991 256:183-188
- Abstract
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- D A Katzka,
- J C Reynolds,
- A D King,
- and S Cohen
Low dose verapamil and nitroprusside distinguish tonic from cholinergic-induced contractions in in vivo feline lower esophageal sphincter.
J Pharmacol Exp Ther January 1991 256:189-193
- Abstract
- Full Text (PDF)
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- M J Van Diest,
- T J Verbeuren,
- and A G Herman
15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase.
J Pharmacol Exp Ther January 1991 256:194-203
- Abstract
- Full Text (PDF)
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- B Borowsky and
- C M Kuhn
Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation.
J Pharmacol Exp Ther January 1991 256:204-210
- Abstract
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- D B Vaupel and
- E J Cone
Pharmacodynamic and pharmacokinetic actions of ketocyclazocine enantiomers in the dog: absence of sigma- or phencyclidine-like activity.
J Pharmacol Exp Ther January 1991 256:211-221
- Abstract
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- M I Steinberg,
- S A Wiest,
- K M Zimmerman,
- P J Ertel,
- K G Bemis,
- and D W Robertson
Chiral recognition of pinacidil and its 3-pyridyl isomer by canine cardiac and smooth muscle: antagonism by sulfonylureas.
J Pharmacol Exp Ther January 1991 256:222-229
- Abstract
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- C J Schmidt,
- V L Taylor,
- G M Abbate,
- and T R Nieduzak
5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.
J Pharmacol Exp Ther January 1991 256:230-235
- Abstract
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- P C Levesque and
- W D Atchison
Disruption of brain mitochondrial calcium sequestration by methylmercury.
J Pharmacol Exp Ther January 1991 256:236-242
- Abstract
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- M Floreani and
- F Carpenedo
Modifications of cardiac contractility by redox cycling alkylating and mixed redox cycling/alkylating quinones.
J Pharmacol Exp Ther January 1991 256:243-248
- Abstract
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- J A Bauer and
- H L Fung
Differential hemodynamic effects and tolerance properties of nitroglycerin and an S-nitrosothiol in experimental heart failure.
J Pharmacol Exp Ther January 1991 256:249-254
- Abstract
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- C C Chao,
- T W Molitor,
- G Gekker,
- M P Murtaugh,
- and P K Peterson
Cocaine-mediated suppression of superoxide production by human peripheral blood mononuclear cells.
J Pharmacol Exp Ther January 1991 256:255-258
- Abstract
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- C K Kellogg,
- R J Primus,
- and D Bitran
Sexually dimorphic influence of prenatal exposure to diazepam on behavioral responses to environmental challenge and on gamma-aminobutyric acid (GABA)-stimulated chloride uptake in the brain.
J Pharmacol Exp Ther January 1991 256:259-265
- Abstract
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- C Moummi,
- G W Gullikson,
- M B Grisham,
- and T S Gaginella
Differential effects of reactive oxygen metabolites on neurally stimulated and nonstimulated guinea pig ileum.
J Pharmacol Exp Ther January 1991 256:266-271
- Abstract
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- N Yoshida,
- A Mizumoto,
- Y Iwanaga,
- and Z Itoh
Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs.
J Pharmacol Exp Ther January 1991 256:272-278
- Abstract
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- S F Flaim,
- M M Gleason,
- A Hedberg,
- R P Shank,
- J R McCullough,
- A Gill,
- B P Damiano,
- M D Brannan,
- and J R Carson
Structurally novel antihypertensive compound, McN-5691, is a calcium channel blocker in vascular smooth muscle.
J Pharmacol Exp Ther January 1991 256:279-288
- Abstract
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- C W Xie and
- D V Lewis
Opioid-mediated facilitation of long-term potentiation at the lateral perforant path-dentate granule cell synapse.
J Pharmacol Exp Ther January 1991 256:289-296
- Abstract
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- S S Navran,
- G Allain,
- H F Garcia,
- J C Allen,
- and C L Seidel
Serotonin-induced Na+/K+ pump stimulation in vascular smooth muscle cells. Evidence for coupling to multiple receptor mechanisms.
J Pharmacol Exp Ther January 1991 256:297-303
- Abstract
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- D J Pettibone,
- B V Clineschmidt,
- E V Lis,
- D R Reiss,
- J A Totaro,
- C J Woyden,
- M G Bock,
- R M Freidinger,
- R D Tung,
- and D F Veber
In vitro pharmacological profile of a novel structural class of oxytocin antagonists.
J Pharmacol Exp Ther January 1991 256:304-308
- Abstract
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- T Wang and
- Y L Chan
The role of phosphoinositide turnover in mediating the biphasic effect of angiotensin II on renal tubular transport.
J Pharmacol Exp Ther January 1991 256:309-317
- Abstract
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- M Gwilt,
- J E Arrowsmith,
- K J Blackburn,
- R A Burges,
- P E Cross,
- H W Dalrymple,
- and A J Higgins
UK-68,798: a novel, potent and highly selective class III antiarrhythmic agent which blocks potassium channels in cardiac cells.
J Pharmacol Exp Ther January 1991 256:318-324
- Abstract
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- G Zuanetti and
- P B Corr
Antiarrhythmic efficacy of a new class III agent, UK-68,798, during chronic myocardial infarction: evaluation using three-dimensional mapping.
J Pharmacol Exp Ther January 1991 256:325-334
- Abstract
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- C R Albrightson-Winslow,
- B Brickson,
- D P Brooks,
- W M Bryan,
- N Caldwell,
- L B Kinter,
- M L Moore,
- P Nambi,
- F L Stassen,
- and W F Huffman
Vasopressin antidiuretic agonist and antagonist activity in dogs: structural and stereochemical relationship between bridge and carboxyl terminus.
J Pharmacol Exp Ther January 1991 256:335-340
- Abstract
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- P Blandina,
- J Goldfarb,
- J Walcott,
- and J P Green
Serotonergic modulation of the release of endogenous norepinephrine from rat hypothalamic slices.
J Pharmacol Exp Ther January 1991 256:341-347
- Abstract
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- J Ichikawa and
- H Y Meltzer
Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens.
J Pharmacol Exp Ther January 1991 256:348-357
- Abstract
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- J A Miller,
- N L Velayo,
- R C Dage,
- and D Rampe
High affinity [3H]glibenclamide binding sites in rat neuronal and cardiac tissue: localization and developmental characteristics.
J Pharmacol Exp Ther January 1991 256:358-364
- Abstract
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- X Nair,
- J Quigley,
- K M Tramposch,
- F I Carroll,
- A H Lewin,
- and I Kiss
BMY 30047: a novel topically active retinoid with low local and systemic toxicity.
J Pharmacol Exp Ther January 1991 256:365-370
- Abstract
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- K Fujino,
- S Nakaya,
- T Wakatsuki,
- Y Miyoshi,
- Y Nakaya,
- H Mori,
- and I Inoue
Effects of nitroglycerin on ATP-induced Ca(++)-mobilization, Ca(++)-activated K channels and contraction of cultured smooth muscle cells of porcine coronary artery.
J Pharmacol Exp Ther January 1991 256:371-377
- Abstract
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- T Nabeshima,
- A Katoh,
- H Ishimaru,
- Y Yoneda,
- K Ogita,
- K Murase,
- H Ohtsuka,
- K Inari,
- T Fukuta,
- and T Kameyama
Carbon monoxide-induced delayed amnesia, delayed neuronal death and change in acetylcholine concentration in mice.
J Pharmacol Exp Ther January 1991 256:378-384
- Abstract
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- E Chávez,
- C Zazueta,
- A Osornio,
- J A Holguín,
- and M E Miranda
Protective behavior of captopril on Hg(++)-induced toxicity on kidney mitochondria. In vivo and in vitro experiments.
J Pharmacol Exp Ther January 1991 256:385-390
- Abstract
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- S Kanekal,
- C Plopper,
- D Morin,
- and A Buckpitt
Metabolism and cytotoxicity of naphthalene oxide in the isolated perfused mouse lung.
J Pharmacol Exp Ther January 1991 256:391-401
- Abstract
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- K Kato,
- P S Puttfarcken,
- W E Lyons,
- and J T Coyle
Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures.
J Pharmacol Exp Ther January 1991 256:402-411
- Abstract
- Full Text (PDF)
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- L J Dahm,
- A E Schultze,
- and R A Roth
An antibody to neutrophils attenuates alpha-naphthylisothiocyanate-induced liver injury.
J Pharmacol Exp Ther January 1991 256:412-420
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

DMPS as a rescue agent for the nephropathy induced by mercuric chloride.

Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins.

Noncontractile acetylcholine receptor-operated Ca++ mobilization: suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle.

Enhancing effect by nicotinic acetylcholine receptor channel blockers, including beta-eudesmol, on succinylcholine-induced inhibition of twitch tension and intracellular Ca++ in mouse diaphragm muscle.

Persistent effects of interleukin-1 on smooth muscle preparations from adrenalectomized rats: implications for increased phospholipase-A2 activity via stimulation of 5-lipoxygenase.

Formation of endothelium-derived relaxing factor in porcine kidney epithelial LLC-PK1 cells: an intra- and intercellular messenger for activation of soluble guanylate cyclase.

Evidence that two stereochemically different alpha-2 adrenoceptors modulate norepinephrine release in rat cerebral cortex.

Inhibition of endothelium-dependent relaxations by phorbol myristate acetate in canine coronary arteries: role of a pertussis toxin-sensitive G-protein.

Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine.

Role of adenosine receptors in caffeine tolerance.

Insight into interstitial drug disposition: lymph concentrations of lidocaine, procainamide and meperidine in the hindquarters of unanesthetized and anesthetized sheep.

Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice.

Electrophysiological studies on the interaction of 5-hydroxytryptamine with sympathetic transmission in the guinea pig inferior mesenteric artery and ganglion.

gamma-Aminobutyric acid (GABA) stimulates somatostatin release following activation of a GABA uptake carrier located on somatostatin nerve endings of rat cerebral cortex.

Characterization of LY233569 on 5-lipoxygenase and reperfusion injury of ischemic myocardium.

Protein kinase C translocation in rat stomach fundus: effects of serotonin, carbamylcholine and phorbol dibutyrate.

Regional and systemic hemodynamic effects of parathyroid hormone-related protein: preservation of cardiac function and coronary and renal flow with reduced blood pressure.

Behavioral and neurochemical interactions between cocaine and buprenorphine: implications for the pharmacotherapy of cocaine abuse.

Potassium-induced contraction in the lamb proximal urethra: involvement of norepinephrine and different calcium entry pathways.

Quinidine inhibits prolactin secretion induced by thyrotropin-releasing hormone, high medium potassium or hyposmolarity in GH4C1 cells.

Concentration-dependence of acetylcholine-induced changes in calcium and tension in swine trachealis.

Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey.

Voltage clamp analysis reveals multiple populations of quanta released at neuromuscular junctions of rats treated with 2,4-dithiobiuret.

Characterization of serotonin receptors in isolated rat intramyocardial coronary artery.

Calcium antagonist effects on low-threshold (T-type) calcium current in rat isolated hippocampal CA1 pyramidal neurons.

Tissue distribution, excretion and hepatic biotransformation of microcystin-LR in mice.

A comparison of the hemodynamic effects of endothelin-1 and sarafotoxin S6b in conscious rats.

Low dose verapamil and nitroprusside distinguish tonic from cholinergic-induced contractions in in vivo feline lower esophageal sphincter.

15-lipoxygenase metabolites of arachidonic acid evoke contractions and relaxations in isolated canine arteries: role of thromboxane receptors, endothelial cells and cyclooxygenase.

Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation.

Pharmacodynamic and pharmacokinetic actions of ketocyclazocine enantiomers in the dog: absence of sigma- or phencyclidine-like activity.

Chiral recognition of pinacidil and its 3-pyridyl isomer by canine cardiac and smooth muscle: antagonism by sulfonylureas.

5-HT2 antagonists stereoselectively prevent the neurotoxicity of 3,4-methylenedioxymethamphetamine by blocking the acute stimulation of dopamine synthesis: reversal by L-dopa.

Disruption of brain mitochondrial calcium sequestration by methylmercury.

Modifications of cardiac contractility by redox cycling alkylating and mixed redox cycling/alkylating quinones.

Differential hemodynamic effects and tolerance properties of nitroglycerin and an S-nitrosothiol in experimental heart failure.

Cocaine-mediated suppression of superoxide production by human peripheral blood mononuclear cells.

Sexually dimorphic influence of prenatal exposure to diazepam on behavioral responses to environmental challenge and on gamma-aminobutyric acid (GABA)-stimulated chloride uptake in the brain.

Differential effects of reactive oxygen metabolites on neurally stimulated and nonstimulated guinea pig ileum.

Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs.

Structurally novel antihypertensive compound, McN-5691, is a calcium channel blocker in vascular smooth muscle.

Opioid-mediated facilitation of long-term potentiation at the lateral perforant path-dentate granule cell synapse.

Serotonin-induced Na+/K+ pump stimulation in vascular smooth muscle cells. Evidence for coupling to multiple receptor mechanisms.

In vitro pharmacological profile of a novel structural class of oxytocin antagonists.

The role of phosphoinositide turnover in mediating the biphasic effect of angiotensin II on renal tubular transport.

UK-68,798: a novel, potent and highly selective class III antiarrhythmic agent which blocks potassium channels in cardiac cells.

Antiarrhythmic efficacy of a new class III agent, UK-68,798, during chronic myocardial infarction: evaluation using three-dimensional mapping.

Vasopressin antidiuretic agonist and antagonist activity in dogs: structural and stereochemical relationship between bridge and carboxyl terminus.

Serotonergic modulation of the release of endogenous norepinephrine from rat hypothalamic slices.

Differential effects of repeated treatment with haloperidol and clozapine on dopamine release and metabolism in the striatum and the nucleus accumbens.

High affinity [3H]glibenclamide binding sites in rat neuronal and cardiac tissue: localization and developmental characteristics.

BMY 30047: a novel topically active retinoid with low local and systemic toxicity.

Effects of nitroglycerin on ATP-induced Ca(++)-mobilization, Ca(++)-activated K channels and contraction of cultured smooth muscle cells of porcine coronary artery.

Carbon monoxide-induced delayed amnesia, delayed neuronal death and change in acetylcholine concentration in mice.

Protective behavior of captopril on Hg(++)-induced toxicity on kidney mitochondria. In vivo and in vitro experiments.

Metabolism and cytotoxicity of naphthalene oxide in the isolated perfused mouse lung.

Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures.

An antibody to neutrophils attenuates alpha-naphthylisothiocyanate-induced liver injury.

This Issue

Current Issue