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Table of Contents
December 1990; 255 (3)
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G J Trachte
,
C M Ferrario
,
and
M C Khosla
Selective blockade of angiotensin responses in the rabbit isolated vas deferens by angiotensin receptor antagonists.
J Pharmacol Exp Ther
December 1990
255
:
929
-
934
Abstract
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H Jaeschke
Glutathione disulfide formation and oxidant stress during acetaminophen-induced hepatotoxicity in mice in vivo: the protective effect of allopurinol.
J Pharmacol Exp Ther
December 1990
255
:
935
-
941
Abstract
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L Rakotoarisoa
,
I Sayet
,
C Mironneau
,
and
J Mironneau
Selective modulation by membrane potential of desmethoxyverapamil binding to calcium channels in rat portal vein.
J Pharmacol Exp Ther
December 1990
255
:
942
-
947
Abstract
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P Lebrun
,
M H Antoine
,
V Devreux
,
M Hermann
,
and
A Herchuelz
Paradoxical inhibitory effect of cromakalim on 86Rb outflow from pancreatic islet cells.
J Pharmacol Exp Ther
December 1990
255
:
948
-
954
Abstract
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E Puil
,
H el-Beheiry
,
and
K G Baimbridge
Anesthetic effects on glutamate-stimulated increase in intraneuronal calcium.
J Pharmacol Exp Ther
December 1990
255
:
955
-
961
Abstract
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H O Heuer
,
J Casals-Stenzel
,
G Muacevic
,
and
K H Weber
Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor.
J Pharmacol Exp Ther
December 1990
255
:
962
-
968
Abstract
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J B Pritchard
Rat renal cortical slices demonstrate p-aminohippurate/glutarate exchange and sodium/glutarate coupled p-aminohippurate transport.
J Pharmacol Exp Ther
December 1990
255
:
969
-
975
Abstract
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P U Dubuc
and
C M Peterson
Ineffectiveness of parenteral fluoxetine or RU-486 to alter long-term food intake, body weight or body composition of genetically obese mice.
J Pharmacol Exp Ther
December 1990
255
:
976
-
979
Abstract
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Y Hamagishi
,
S Murata
,
H Kamei
,
T Oki
,
O Adachi
,
and
M Ameyama
New biological properties of pyrroloquinoline quinone and its related compounds: inhibition of chemiluminescence, lipid peroxidation and rat paw edema.
J Pharmacol Exp Ther
December 1990
255
:
980
-
985
Abstract
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W H Griffith
and
J A Sim
Comparison of 4-aminopyridine and tetrahydroaminoacridine on basal forebrain neurons.
J Pharmacol Exp Ther
December 1990
255
:
986
-
993
Abstract
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V B Schini
,
Z S Katusic
,
and
P M Vanhoutte
Neurohypophyseal peptides and tachykinins stimulate the production of cyclic GMP in cultured porcine aortic endothelial cells.
J Pharmacol Exp Ther
December 1990
255
:
994
-
1000
Abstract
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I J Reynolds
Arcaine uncovers dual interactions of polyamines with the N-methyl-D-aspartate receptor.
J Pharmacol Exp Ther
December 1990
255
:
1001
-
1007
Abstract
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R E Howell
Multiple mechanisms of xanthine actions on airway reactivity.
J Pharmacol Exp Ther
December 1990
255
:
1008
-
1014
Abstract
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T E Raya
,
R G Gay
,
and
S Goldman
Selective vasopressin inhibition in rats with heart failure decreases afterload and results in venodilatation.
J Pharmacol Exp Ther
December 1990
255
:
1015
-
1020
Abstract
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S Seiler
,
C L Brassard
,
A J Arnold
,
N A Meanwell
,
J S Fleming
,
and
S L Keely, Jr
Octimibate inhibition of platelet aggregation: stimulation of adenylate cyclase through prostacyclin receptor activation.
J Pharmacol Exp Ther
December 1990
255
:
1021
-
1026
Abstract
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J U Adams
,
C A Paronis
,
and
S G Holtzman
Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using beta-funaltrexamine.
J Pharmacol Exp Ther
December 1990
255
:
1027
-
1032
Abstract
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T Okano
,
H Maegawa
,
K Inui
,
and
R Hori
Interaction of ofloxacin with organic cation transport system in rat renal brush-border membranes.
J Pharmacol Exp Ther
December 1990
255
:
1033
-
1037
Abstract
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N A Castle
Bupivacaine inhibits the transient outward K+ current but not the inward rectifier in rat ventricular myocytes.
J Pharmacol Exp Ther
December 1990
255
:
1038
-
1046
Abstract
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J Zawilska
and
P M Iuvone
Alpha-2 adrenergic activity of bromocriptine and quinpirole in chicken pineal gland. Effects on melatonin synthesis and [3H]rauwolscine binding.
J Pharmacol Exp Ther
December 1990
255
:
1047
-
1052
Abstract
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D C Eikenburg
Effects of chronic norepinephrine administration on sympathetic neurotransmission in the isolated perfused rat kidney.
J Pharmacol Exp Ther
December 1990
255
:
1053
-
1059
Abstract
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A I Sacaan
and
K M Johnson
Spermidine reverses arcaine's inhibition of N-methyl-D-aspartate-induced hippocampal [3H]norepinephrine release.
J Pharmacol Exp Ther
December 1990
255
:
1060
-
1063
Abstract
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X M Yang
,
A L Gorman
,
and
A J Dunn
The involvement of central noradrenergic systems and corticotropin-releasing factor in defensive-withdrawal behavior in rats.
J Pharmacol Exp Ther
December 1990
255
:
1064
-
1070
Abstract
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H E Shannon
,
K G Bemis
,
J C Hendrix
,
and
J S Ward
Interactions between scopolamine and muscarinic cholinergic agonists or cholinesterase inhibitors on spatial alternation performance in rats.
J Pharmacol Exp Ther
December 1990
255
:
1071
-
1077
Abstract
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Y Isobe
,
H Nagai
,
M Muramatsu
,
H Aihara
,
and
S Otomo
Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats.
J Pharmacol Exp Ther
December 1990
255
:
1078
-
1082
Abstract
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W M Armstead
,
R Mirro
,
D W Busija
,
and
C W Leffler
Prostanoids modulate opioid cerebrovascular responses in newborn pigs.
J Pharmacol Exp Ther
December 1990
255
:
1083
-
1089
Abstract
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Y Itoh
,
R Oishi
,
M Nishibori
,
and
K Saeki
In vivo measurement of noradrenaline and 3,4-dihydroxyphenylethyleneglycol in the rat hypothalamus by microdialysis: effects of various drugs affecting noradrenaline metabolism.
J Pharmacol Exp Ther
December 1990
255
:
1090
-
1097
Abstract
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R Oberlender
and
D E Nichols
(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity.
J Pharmacol Exp Ther
December 1990
255
:
1098
-
1106
Abstract
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M H Ossipov
,
S Harris
,
P Lloyd
,
and
E Messineo
An isobolographic analysis of the antinociceptive effect of systemically and intrathecally administered combinations of clonidine and opiates.
J Pharmacol Exp Ther
December 1990
255
:
1107
-
1116
Abstract
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P J Pauwels
,
H P Van Assouw
,
L Peeters
,
and
J E Leysen
Neurotoxic action of veratridine in rat brain neuronal cultures: mechanism of neuroprotection by Ca++ antagonists nonselective for slow Ca++ channels.
J Pharmacol Exp Ther
December 1990
255
:
1117
-
1122
Abstract
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R R Griffiths
,
S M Evans
,
S J Heishman
,
K L Preston
,
C A Sannerud
,
B Wolf
,
and
P P Woodson
Low-dose caffeine physical dependence in humans.
J Pharmacol Exp Ther
December 1990
255
:
1123
-
1132
Abstract
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E H Ellinwood, Jr
,
A M Nikaido
,
S K Gupta
,
D G Heatherly
,
and
J K Nishita
Comparison of central nervous system and peripheral pharmacodynamics to atropine pharmacokinetics.
J Pharmacol Exp Ther
December 1990
255
:
1133
-
1139
Abstract
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C C Felder
,
P Dieter
,
J Kinsella
,
K Tamura
,
R Y Kanterman
,
and
J Axelrod
A transfected m5 muscarinic acetylcholine receptor stimulates phospholipase A2 by inducing both calcium influx and activation of protein kinase C.
J Pharmacol Exp Ther
December 1990
255
:
1140
-
1147
Abstract
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F J Ehlert
and
L P Tran
Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain.
J Pharmacol Exp Ther
December 1990
255
:
1148
-
1157
Abstract
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C T Dourish
,
M F O'Neill
,
L W Schaffer
,
P K Siegl
,
and
S D Iversen
The cholecystokinin receptor antagonist devazepide enhances morphine-induced analgesia but not morphine-induced respiratory depression in the squirrel monkey.
J Pharmacol Exp Ther
December 1990
255
:
1158
-
1165
Abstract
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D M Pollock
and
T J Opgenorth
Beneficial effect of the atrial natriuretic factor analog A68828 in postischemic acute renal failure.
J Pharmacol Exp Ther
December 1990
255
:
1166
-
1169
Abstract
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C Prior
,
J F Fiekers
,
F Henderson
,
J Dempster
,
I G Marshall
,
and
R L Parsons
End-plate ion channel block produced by lincosamide antibiotics and their chemical analogs.
J Pharmacol Exp Ther
December 1990
255
:
1170
-
1176
Abstract
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M A Czuba
,
D J Morgan
,
M S Ching
,
G W Mihaly
,
K J Hardy
,
and
R A Smallwood
Ontogeny of fetal renal organic cation excretion: a study with cimetidine and ranitidine during the latter half of gestation in the pregnant ewe.
J Pharmacol Exp Ther
December 1990
255
:
1177
-
1182
Abstract
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K W Hunter, Jr
,
A A Brimfield
,
A T Knower
,
J A Powell
,
and
G Z Feuerstein
Reversal of intracellular toxicity of the trichothecene mycotoxin T-2 with monoclonal antibody.
J Pharmacol Exp Ther
December 1990
255
:
1183
-
1187
Abstract
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M P Gupta
,
N Makino
,
S Takeo
,
M Kaneko
,
and
N S Dhalla
Cardiac sarcolemma as a possible site of action of caffeine in rat heart.
J Pharmacol Exp Ther
December 1990
255
:
1188
-
1194
Abstract
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C Brodie
and
S R Sampson
Effects of ethanol on voltage-sensitive Na-channels in cultured skeletal muscle: up-regulation as a result of chronic treatment.
J Pharmacol Exp Ther
December 1990
255
:
1195
-
1201
Abstract
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M S Dar
Central adenosinergic system involvement in ethanol-induced motor incoordination in mice.
J Pharmacol Exp Ther
December 1990
255
:
1202
-
1209
Abstract
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T Kanayama
,
Y Kimura
,
K Iseki
,
Y Hayashi
,
Y Tamao
,
and
S Mizogami
Antithrombotic effects of KP-10614, a novel and stable prostacyclin (PGI2) analog.
J Pharmacol Exp Ther
December 1990
255
:
1210
-
1217
Abstract
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I Takahashi
,
E Kobayashi
,
H Nakano
,
C Murakata
,
H Saitoh
,
K Suzuki
,
and
T Tamaoki
Potent selective inhibition of 7-O-methyl UCN-01 against protein kinase C.
J Pharmacol Exp Ther
December 1990
255
:
1218
-
1221
Abstract
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F W Lee
,
T Salmonson
,
C H Metzler
,
and
L Z Benet
Pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its two dinitrate metabolites in conscious dogs.
J Pharmacol Exp Ther
December 1990
255
:
1222
-
1229
Abstract
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S J Ward
,
D Mastriani
,
F Casiano
,
and
R Arnold
Pravadoline: profile in isolated tissue preparations.
J Pharmacol Exp Ther
December 1990
255
:
1230
-
1239
Abstract
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A Poling
,
J Cleary
,
K Berens
,
and
T Thompson
Neuroleptics and learning: effects of haloperidol, molindone, mesoridazine and thioridazine on the behavior of pigeons under a repeated acquisition procedure.
J Pharmacol Exp Ther
December 1990
255
:
1240
-
1245
Abstract
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S M Evans
,
F R Funderburk
,
and
R R Griffiths
Zolpidem and triazolam in humans: behavioral and subjective effects and abuse liability.
J Pharmacol Exp Ther
December 1990
255
:
1246
-
1255
Abstract
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E A Kowaluk
and
H L Fung
Spontaneous liberation of nitric oxide cannot account for in vitro vascular relaxation by S-nitrosothiols.
J Pharmacol Exp Ther
December 1990
255
:
1256
-
1264
Abstract
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D M Burnett
,
J F Bowyer
,
J M Masserano
,
and
N R Zahniser
Effect of aging on alpha-1 adrenergic stimulation of phosphoinositide hydrolysis in various regions of rat brain.
J Pharmacol Exp Ther
December 1990
255
:
1265
-
1270
Abstract
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C P France
,
Y Lu
,
and
J H Woods
Interactions between N-methyl-D-aspartate and CGS 19755 administered intramuscularly and intracerebroventricularly in pigeons.
J Pharmacol Exp Ther
December 1990
255
:
1271
-
1277
Abstract
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R J Knapp
,
L K Vaughn
,
S N Fang
,
C L Bogert
,
M S Yamamura
,
V J Hruby
,
and
H I Yamamura
A new, highly selective CCK-B receptor radioligand ([3H][N-methyl-Nle28,31]CCK26-33): evidence for CCK-B receptor heterogeneity.
J Pharmacol Exp Ther
December 1990
255
:
1278
-
1286
Abstract
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D M Ignar
and
C M Kuhn
Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat.
J Pharmacol Exp Ther
December 1990
255
:
1287
-
1295
Abstract
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M A Wallace
and
E Claro
Comparison of serotoninergic to muscarinic cholinergic stimulation of phosphoinositide-specific phospholipase C in rat brain cortical membranes.
J Pharmacol Exp Ther
December 1990
255
:
1296
-
1300
Abstract
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D D Schoepp
,
P L Ornstein
,
J D Leander
,
D Lodge
,
C R Salhoff
,
S Zeman
,
and
D M Zimmerman
Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.
J Pharmacol Exp Ther
December 1990
255
:
1301
-
1308
Abstract
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M H Fernandes
and
P Soares-da-Silva
Effects of MAO-A and MAO-B selective inhibitors Ro 41-1049 and Ro 19-6327 on the deamination of newly formed dopamine in the rat kidney.
J Pharmacol Exp Ther
December 1990
255
:
1309
-
1313
Abstract
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J J Beutler
,
H A Koomans
,
J A Bijlsma
,
and
E J Dorhout Mees
Renal actions of theophylline and atrial natriuretic peptide in humans: a comparison by means of clearance studies.
J Pharmacol Exp Ther
December 1990
255
:
1314
-
1319
Abstract
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M C Dyson
,
J A Bellan
,
R K Minkes
,
R C Beckerman
,
M J Wegmann
,
P Braquet
,
D B McNamara
,
and
P J Kadowitz
Influence of SK&F 95587 and BN 50730 on bronchoconstrictor responses in the cat.
J Pharmacol Exp Ther
December 1990
255
:
1320
-
1327
Abstract
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J G Wettstein
,
E S Teeple
,
and
W H Morse
Respiratory effects of benzodiazepine-related drugs in awake rhesus monkeys.
J Pharmacol Exp Ther
December 1990
255
:
1328
-
1334
Abstract
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L E Schechter
,
F J Bolaños
,
H Gozlan
,
L Lanfumey
,
S Haj-Dahmane
,
A M Laporte
,
C M Fattaccini
,
and
M Hamon
Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies.
J Pharmacol Exp Ther
December 1990
255
:
1335
-
1347
Abstract
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O A Fasehun
,
S S Gross
,
L E Rubin
,
E A Jaffe
,
O W Griffith
,
and
R Levi
L-arginine, but not N alpha-benzoyl-L-arginine ethyl ester, is a precursor of endothelium-derived relaxing factor.
J Pharmacol Exp Ther
December 1990
255
:
1348
-
1353
Abstract
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X Pascaud
,
J P Defaux
,
C Rozé
,
and
J L Junien
Effect of selective sigma ligands on duodenal alkaline secretion in the rat.
J Pharmacol Exp Ther
December 1990
255
:
1354
-
1359
Abstract
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D G Soergel
,
F Gusovsky
,
T Yasumoto
,
and
J W Daly
Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown.
J Pharmacol Exp Ther
December 1990
255
:
1360
-
1365
Abstract
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L F Jones
and
R L Tackett
Chronic cocaine treatment enhances the responsiveness of the left anterior descending coronary artery and the femoral artery to vasoactive substances.
J Pharmacol Exp Ther
December 1990
255
:
1366
-
1370
Abstract
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B Fromenty
,
C Fisch
,
G Labbe
,
C Degott
,
D Deschamps
,
A Berson
,
P Letteron
,
and
D Pessayre
Amiodarone inhibits the mitochondrial beta-oxidation of fatty acids and produces microvesicular steatosis of the liver in mice.
J Pharmacol Exp Ther
December 1990
255
:
1371
-
1376
Abstract
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B Fromenty
,
C Fisch
,
A Berson
,
P Letteron
,
D Larrey
,
and
D Pessayre
Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II.
J Pharmacol Exp Ther
December 1990
255
:
1377
-
1384
Abstract
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S Imaoka
,
K Enomoto
,
Y Oda
,
A Asada
,
M Fujimori
,
T Shimada
,
S Fujita
,
F P Guengerich
,
and
Y Funae
Lidocaine metabolism by human cytochrome P-450s purified from hepatic microsomes: comparison of those with rat hepatic cytochrome P-450s.
J Pharmacol Exp Ther
December 1990
255
:
1385
-
1391
Abstract
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P J Robinson
,
H C Cheng
,
C K Black
,
C J Schmidt
,
T Kariya
,
W D Jones
,
and
R C Dage
MDL 27,032 [4-propyl-5-(4-pyridinyl)-2(3H)-oxazolone], an active site-directed inhibitor of protein kinase C and cyclic AMP-dependent protein kinase that relaxes vascular smooth muscle.
J Pharmacol Exp Ther
December 1990
255
:
1392
-
1398
Abstract
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J J Anderson
and
J A DiMicco
Effect of local inhibition of gamma-aminobutyric acid uptake in the dorsomedial hypothalamus on extracellular levels of gamma-aminobutyric acid and on stress-induced tachycardia: a study using microdialysis.
J Pharmacol Exp Ther
December 1990
255
:
1399
-
1407
Abstract
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G M Kalabis
and
P G Wells
Biphasic modulation of acetaminophen bioactivation and hepatotoxicity by pretreatment with the interferon inducer polyinosinic-polycytidylic acid.
J Pharmacol Exp Ther
December 1990
255
:
1408
-
1419
Abstract
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Article
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ERRATUM
J Pharmacol Exp Ther
December 1990
255
:
1407
Abstract
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