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Table of Contents
November 1990; 255 (2)
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K M Hull
and
T J Maher
L-tyrosine potentiates the anorexia induced by mixed-acting sympathomimetic drugs in hyperphagic rats.
J Pharmacol Exp Ther
November 1990
255
:
403
-
409
Abstract
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H U Bryant
and
R E Roudebush
Suppressive effects of morphine pellet implants on in vivo parameters of immune function.
J Pharmacol Exp Ther
November 1990
255
:
410
-
414
Abstract
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R P Garay
,
J P Labaune
,
D Mesangeau
,
C Nazaret
,
T Imbert
,
and
G Moinet
CRE 10904 [2-(p-fluorophenoxy), 1-(o-hydroxyphenyl)-ethane]: a new diuretic and antihypertensive drug acting by in vivo sulfation.
J Pharmacol Exp Ther
November 1990
255
:
415
-
422
Abstract
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S P Han
,
L Naes
,
and
T C Westfall
Calcitonin gene-related peptide is the endogenous mediator of nonadrenergic-noncholinergic vasodilation in rat mesentery.
J Pharmacol Exp Ther
November 1990
255
:
423
-
428
Abstract
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C Ripoll
,
W J Lederer
,
and
C G Nichols
Modulation of ATP-sensitive K+ channel activity and contractile behavior in mammalian ventricle by the potassium channel openers cromakalim and RP49356.
J Pharmacol Exp Ther
November 1990
255
:
429
-
435
Abstract
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P P Sokol
Effect of DQ-2556, a new cephalosporin, on organic ion transport in renal plasma membrane vesicles from the dog, rabbit and rat.
J Pharmacol Exp Ther
November 1990
255
:
436
-
441
Abstract
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F Zavala
,
V Taupin
,
and
B Descamps-Latscha
In vivo treatment with benzodiazepines inhibits murine phagocyte oxidative metabolism and production of interleukin 1, tumor necrosis factor and interleukin-6.
J Pharmacol Exp Ther
November 1990
255
:
442
-
450
Abstract
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A I Faden
,
R Shirane
,
L H Chang
,
T L James
,
M Lemke
,
and
P R Weinstein
Opiate-receptor antagonist improves metabolic recovery and limits neurochemical alterations associated with reperfusion after global brain ischemia in rats.
J Pharmacol Exp Ther
November 1990
255
:
451
-
458
Abstract
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E R Jacobs
and
T E DeCoursey
Mechanisms of potassium channel block in rat alveolar epithelial cells.
J Pharmacol Exp Ther
November 1990
255
:
459
-
472
Abstract
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M Y Farhat
,
P W Ramwell
,
and
G Thomas
Endothelium-mediated effects of N-substituted arginines on the isolated perfused rat kidney.
J Pharmacol Exp Ther
November 1990
255
:
473
-
477
Abstract
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C J Schmidt
,
G M Abbate
,
C K Black
,
and
V L Taylor
Selective 5-hydroxytryptamine2 receptor antagonists protect against the neurotoxicity of methylenedioxymethamphetamine in rats.
J Pharmacol Exp Ther
November 1990
255
:
478
-
483
Abstract
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T Shimizu
,
T Kawabata
,
and
M Nakamura
Protective effect of a novel calcium blocker, S-312-d, on ischemic acute renal failure in rat.
J Pharmacol Exp Ther
November 1990
255
:
484
-
490
Abstract
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P G Cox
,
W M Moons
,
F G Russel
,
and
C A van Ginneken
Renal disposition and effects of naproxen and its l-enantiomer in the isolated perfused rat kidney.
J Pharmacol Exp Ther
November 1990
255
:
491
-
496
Abstract
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J G Drewett
,
R J Ziegler
,
and
G J Trachte
Neuromodulatory effects of atrial natriuretic factor are independent of guanylate cyclase in adrenergic neuronal pheochromocytoma cells.
J Pharmacol Exp Ther
November 1990
255
:
497
-
503
Abstract
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Y Kumagai
,
T Todaka
,
and
S Toki
A new metabolic pathway of morphine: in vivo and in vitro formation of morphinone and morphine-glutathione adduct in guinea pig.
J Pharmacol Exp Ther
November 1990
255
:
504
-
510
Abstract
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D R Haubrich
,
S J Ward
,
E Baizman
,
M R Bell
,
J Bradford
,
R Ferrari
,
M Miller
,
M Perrone
,
A K Pierson
,
and
J K Saelens
Pharmacology of pravadoline: a new analgesic agent.
J Pharmacol Exp Ther
November 1990
255
:
511
-
522
Abstract
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M Feria
,
C Alvarez
,
J Domínguez
,
A Sánchez
,
and
J Boada
Naloxone potentiation of cardiovascular responses to sympathomimetic amines in the rat.
J Pharmacol Exp Ther
November 1990
255
:
523
-
528
Abstract
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E Freneaux
,
B Fromenty
,
A Berson
,
G Labbe
,
C Degott
,
P Letteron
,
D Larrey
,
and
D Pessayre
Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids.
J Pharmacol Exp Ther
November 1990
255
:
529
-
535
Abstract
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A L Giordano
,
B Nock
,
and
T J Cicero
Antagonist-induced up-regulation of the putative epsilon opioid receptor in rat brain: comparison with kappa, mu and delta opioid receptors.
J Pharmacol Exp Ther
November 1990
255
:
536
-
540
Abstract
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W Löscher
,
D Hönack
,
R Scherkl
,
A Hashem
,
and
H H Frey
Pharmacokinetics, anticonvulsant efficacy and adverse effects of the beta-carboline abecarnil, a novel ligand for benzodiazepine receptors, after acute and chronic administration in dogs.
J Pharmacol Exp Ther
November 1990
255
:
541
-
548
Abstract
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H E Shannon
and
S C Peters
A comparison of the effects of cholinergic and dopaminergic agents on scopolamine-induced hyperactivity in mice.
J Pharmacol Exp Ther
November 1990
255
:
549
-
553
Abstract
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J Hidalgo
,
J S Garvey
,
and
A Armario
On the metallothionein, glutathione and cysteine relationship in rat liver.
J Pharmacol Exp Ther
November 1990
255
:
554
-
564
Abstract
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R C Falcone
and
D Aharony
Modulation of ligand binding to leukotriene B4 receptors on guinea pig lung membranes by sulfhydryl modifying reagents.
J Pharmacol Exp Ther
November 1990
255
:
565
-
571
Abstract
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D J Fretland
,
D Widomski
,
B S Tsai
,
J M Zemaitis
,
S Levin
,
S W Djuric
,
R L Shone
,
and
T S Gaginella
Effect of the leukotriene B4 receptor antagonist SC-41930 on colonic inflammation in rat, guinea pig and rabbit.
J Pharmacol Exp Ther
November 1990
255
:
572
-
576
Abstract
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R E Galinsky
,
D H Johnson
,
R E Kane
,
and
M R Franklin
Effect of aging on hepatic biotransformation in female Fischer 344 rats: changes in sulfotransferase activities are consistent with known gender-related changes in pituitary growth hormone secretion in aging animals.
J Pharmacol Exp Ther
November 1990
255
:
577
-
583
Abstract
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P C Wong
,
S D Hart
,
A M Zaspel
,
A T Chiu
,
R J Ardecky
,
R D Smith
,
and
P B Timmermans
Functional studies of nonpeptide angiotensin II receptor subtype-specific ligands: DuP 753 (AII-1) and PD123177 (AII-2).
J Pharmacol Exp Ther
November 1990
255
:
584
-
592
Abstract
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P Polster
,
B Christophe
,
M Van Damme
,
A Houlliche
,
and
P Chatelain
SR 33557, a novel calcium entry blocker. I. In vitro isolated tissue studies.
J Pharmacol Exp Ther
November 1990
255
:
593
-
599
Abstract
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P Nokin
,
M Clinet
,
P Beaufort
,
L Meysmans
,
R Laruel
,
and
P Chatelain
SR 33557, a novel calcium entry blocker. II. Interactions with 1,4-dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes.
J Pharmacol Exp Ther
November 1990
255
:
600
-
607
Abstract
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A I Faden
,
S W Yum
,
M Lemke
,
and
R Vink
Effects of TRH-analog treatment on tissue cations, phospholipids and energy metabolism after spinal cord injury.
J Pharmacol Exp Ther
November 1990
255
:
608
-
614
Abstract
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M T Whittico
,
Y A Gang
,
and
K M Giacomini
Cimetidine transport in isolated brush border membrane vesicles from bovine choroid plexus.
J Pharmacol Exp Ther
November 1990
255
:
615
-
623
Abstract
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B F Thomas
,
D R Compton
,
and
B R Martin
Characterization of the lipophilicity of natural and synthetic analogs of delta 9-tetrahydrocannabinol and its relationship to pharmacological potency.
J Pharmacol Exp Ther
November 1990
255
:
624
-
630
Abstract
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T A Heming
,
C G Vanoye
,
and
A Bidani
Dipyridamole inhibition of HCO3(-)-Cl- exchange in human erythrocytes.
J Pharmacol Exp Ther
November 1990
255
:
631
-
635
Abstract
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J A Qi
,
W D Bowen
,
H I Mosberg
,
R B Rothman
,
and
F Porreca
Opioid agonist and antagonist antinociceptive properties of [D-Ala2,Leu5,Cys6]enkephalin: selective actions at the deltanoncomplexed site.
J Pharmacol Exp Ther
November 1990
255
:
636
-
641
Abstract
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J Turgeon
,
H N Pavlou
,
W Wong
,
C Funck-Brentano
,
and
D M Roden
Genetically determined steady-state interaction between encainide and quinidine in patients with arrhythmias.
J Pharmacol Exp Ther
November 1990
255
:
642
-
649
Abstract
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S A Keitz
,
R Osman
,
W P Clarke
,
J Goldfarb
,
and
S Maayani
Functional interactions in smooth muscle: kinetic characterization of the relaxation and desensitization responses to a beta adrenergic agonist in the rabbit aorta.
J Pharmacol Exp Ther
November 1990
255
:
650
-
656
Abstract
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M Maitre
,
V Hechler
,
P Vayer
,
S Gobaille
,
C D Cash
,
M Schmitt
,
and
J J Bourguignon
A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties.
J Pharmacol Exp Ther
November 1990
255
:
657
-
663
Abstract
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J B Cheng
,
J S Pillar
,
M J Conklyn
,
R Breslow
,
J T Shirley
,
and
H J Showell
Evidence that peptidoleukotriene is a prerequisite for antigen-dependent thromboxane synthesis in IgG1-passively sensitized guinea pig lungs.
J Pharmacol Exp Ther
November 1990
255
:
664
-
671
Abstract
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N A Boughattas
,
F Lévi
,
C Fournier
,
B Hecquet
,
G Lemaigre
,
A Roulon
,
G Mathé
,
and
A Reinberg
Stable circadian mechanisms of toxicity of two platinum analogs (cisplatin and carboplatin) despite repeated dosages in mice.
J Pharmacol Exp Ther
November 1990
255
:
672
-
679
Abstract
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Y Nasa
,
K Ichihara
,
and
Y Abiko
Both d-cis- and l-cis-diltiazem have anti-ischemic action in the isolated, perfused working rat heart.
J Pharmacol Exp Ther
November 1990
255
:
680
-
689
Abstract
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G K Lloyd
,
G Danielou
,
and
F Thuret
The activity of zolpidem and other hypnotics within the gamma-aminobutyric acid (GABAA) receptor supramolecular complex, as determined by 35S-t-butylbicyclophosphorothionate (35S-TBPS) binding to rat cerebral cortex membranes.
J Pharmacol Exp Ther
November 1990
255
:
690
-
696
Abstract
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T R Jones
,
L Charette
,
M L Garcia
,
and
G J Kaczorowski
Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor.
J Pharmacol Exp Ther
November 1990
255
:
697
-
706
Abstract
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T J Cicero
,
M L Adams
,
L O'Connor
,
B Nock
,
E R Meyer
,
and
D Wozniak
Influence of chronic alcohol administration on representative indices of puberty and sexual maturation in male rats and the development of their progeny.
J Pharmacol Exp Ther
November 1990
255
:
707
-
715
Abstract
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T Okaniwa
,
H Echizen
,
T Ishizaki
,
M Kasao
,
and
T Iizuka
Pharmacodynamic characterization of posture-related diuretic and saluretic responses to furosemide in humans.
J Pharmacol Exp Ther
November 1990
255
:
716
-
723
Abstract
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H Tanaka
and
T Tokiwa
Pharmacokinetics of recombinant human granulocyte colony-stimulating factor studied in the rat by a sandwich enzyme-linked immunosorbent assay.
J Pharmacol Exp Ther
November 1990
255
:
724
-
729
Abstract
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K C Kirby
,
M L Stitzer
,
and
S J Heishman
Acute opioid physical dependence in humans: effect of varying the morphine-naloxone interval II.
J Pharmacol Exp Ther
November 1990
255
:
730
-
737
Abstract
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C D Jeck
and
M R Rosen
Use-dependent effects of lidocaine in neonatal and adult ventricular myocardium.
J Pharmacol Exp Ther
November 1990
255
:
738
-
743
Abstract
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W R Martin
,
J W Sloan
,
and
E Wala
Precipitated abstinence in orally dosed benzodiazepine-dependent dogs.
J Pharmacol Exp Ther
November 1990
255
:
744
-
755
Abstract
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J E Bleasdale
,
N R Thakur
,
R S Gremban
,
G L Bundy
,
F A Fitzpatrick
,
R J Smith
,
and
S Bunting
Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.
J Pharmacol Exp Ther
November 1990
255
:
756
-
768
Abstract
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D Paul
,
J A Levison
,
D H Howard
,
C G Pick
,
E F Hahn
,
and
G W Pasternak
Naloxone benzoylhydrazone (NalBzoH) analgesia.
J Pharmacol Exp Ther
November 1990
255
:
769
-
774
Abstract
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K M Merchant
,
L G Bush
,
J W Gibb
,
and
G R Hanson
Neurotensin-dopamine interactions in the substantia nigra of the rat brain.
J Pharmacol Exp Ther
November 1990
255
:
775
-
780
Abstract
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Y N Kwok
,
C McIntosh
,
and
J Brown
Augmentation of release of gastric somatostatin-like immunoreactivity by adenosine, adenosine triphosphate and their analogs.
J Pharmacol Exp Ther
November 1990
255
:
781
-
788
Abstract
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T Nabeshima
,
K Tohyama
,
K Ichihara
,
and
T Kameyama
Effects of benzodiazepines on passive avoidance response and latent learning in mice: relationship to benzodiazepine receptors and the cholinergic neuronal system.
J Pharmacol Exp Ther
November 1990
255
:
789
-
794
Abstract
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C G Parsons
and
A Herz
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for activation by enkephalin-like opioid peptides after cold water swim stress.
J Pharmacol Exp Ther
November 1990
255
:
795
-
802
Abstract
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L Ahtee
,
L M Attila
,
and
K R Carlson
Augmentation of morphine-induced changes in brain monoamine metabolism after chronic naltrexone treatment.
J Pharmacol Exp Ther
November 1990
255
:
803
-
808
Abstract
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P C Chang
,
K Szemeredi
,
E Grossman
,
I J Kopin
,
and
D S Goldstein
Fate of tritiated 6-fluorodopamine in rats: a false neurotransmitter for positron emission tomographic imaging of sympathetic innervation and function.
J Pharmacol Exp Ther
November 1990
255
:
809
-
817
Abstract
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K Masuzawa
,
M Asano
,
T Matsuda
,
Y Imaizumi
,
and
M Watanabe
Possible involvement of ATP-sensitive K+ channels in the relaxant response of dog middle cerebral artery to cromakalim.
J Pharmacol Exp Ther
November 1990
255
:
818
-
825
Abstract
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R Kawai
,
Y Sawada
,
M Channing
,
B Dunn
,
A H Newman
,
K C Rice
,
and
R G Blasberg
Kinetic analysis of the opiate antagonist cyclofoxy in rat brain: simultaneous infusion of active and inactive enantiomers.
J Pharmacol Exp Ther
November 1990
255
:
826
-
835
Abstract
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J F Giudicelli
,
C D la Rochelle
,
and
A Berdeaux
Effects of cromakalim and pinacidil on large epicardial and small coronary arteries in conscious dogs.
J Pharmacol Exp Ther
November 1990
255
:
836
-
842
Abstract
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N M Appel
,
W M Mitchell
,
R K Garlick
,
R A Glennon
,
M Teitler
,
and
E B De Souza
Autoradiographic characterization of (+-)-1-(2,5-dimethoxy-4-[125I] iodophenyl)-2-aminopropane ([125I]DOI) binding to 5-HT2 and 5-HT1c receptors in rat brain.
J Pharmacol Exp Ther
November 1990
255
:
843
-
857
Abstract
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D Beauchamp
,
G Laurent
,
P Maldague
,
S Abid
,
B K Kishore
,
and
P M Tulkens
Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid.
J Pharmacol Exp Ther
November 1990
255
:
858
-
866
Abstract
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B K Kishore
,
Z Kállay
,
P Lambricht
,
G Laurent
,
and
P M Tulkens
Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. I. Polyaspartic acid binds gentamicin and displaces it from negatively charged phospholipid layers in vitro.
J Pharmacol Exp Ther
November 1990
255
:
867
-
874
Abstract
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B K Kishore
,
P Lambricht
,
G Laurent
,
P Maldague
,
R Wagner
,
and
P M Tulkens
Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids.
J Pharmacol Exp Ther
November 1990
255
:
875
-
885
Abstract
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W P Schiemann
,
J M Walther
,
and
I L Buxton
On the ability of endogenous adenosine to regulate purine nucleoside receptor binding of antagonists in smooth muscle membranes.
J Pharmacol Exp Ther
November 1990
255
:
886
-
892
Abstract
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W M Pardridge
,
D Triguero
,
J Buciak
,
and
J Yang
Evaluation of cationized rat albumin as a potential blood-brain barrier drug transport vector.
J Pharmacol Exp Ther
November 1990
255
:
893
-
899
Abstract
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C Alzheimer
and
G ten Bruggencate
Nonopioid actions of the kappa-opioid receptor agonists, U 50488H and U 69593 on electrophysiologic properties of hippocampal CA3 neurons in vitro.
J Pharmacol Exp Ther
November 1990
255
:
900
-
905
Abstract
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H Hara
and
K Kogure
Prevention of hippocampus neuronal damage in ischemic gerbils by a novel lipid peroxidation inhibitor (quinazoline derivative).
J Pharmacol Exp Ther
November 1990
255
:
906
-
913
Abstract
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B A Sabel
,
P Dominiak
,
W Häuser
,
M J During
,
and
A Freese
Levodopa delivery from controlled-release polymer matrix: delivery of more than 600 days in vitro and 225 days of elevated plasma levels after subcutaneous implantation in rats.
J Pharmacol Exp Ther
November 1990
255
:
914
-
922
Abstract
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J Szolcsanyi
,
A Szallasi
,
Z Szallasi
,
F Joo
,
and
P M Blumberg
Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons.
J Pharmacol Exp Ther
November 1990
255
:
923
-
928
Abstract
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November 1990; 255 (2)
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