Table of Contents

April 1990; 253 (1)

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- G Iacono and
- M Vassalle
On the mechanism of the different sensitivity of Purkinje and myocardial fibers to strophanthidin.
J Pharmacol Exp Ther April 1990 253:1-12
- Abstract
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- F J Ehlert,
- F M Delen,
- S H Yun,
- and H A Liem
The interaction of amitriptyline, doxepin, imipramine and their N-methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart.
J Pharmacol Exp Ther April 1990 253:13-19
- Abstract
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- K M Boje and
- H L Fung
Endothelial nitric oxide generating enzyme(s) in the bovine aorta: subcellular location and metabolic characterization.
J Pharmacol Exp Ther April 1990 253:20-26
- Abstract
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- M J Wiester,
- J S Tepper,
- M F Weber,
- and M G Ménache
Histamine and methacholine aerosol bronchial challenge in awake guinea pigs.
J Pharmacol Exp Ther April 1990 253:27-33
- Abstract
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- R Sabra,
- K Takahashi,
- R A Branch,
- and K F Badr
Mechanisms of amphotericin B-induced reduction of the glomerular filtration rate: a micropuncture study.
J Pharmacol Exp Ther April 1990 253:34-37
- Abstract
- Full Text (PDF)
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- J Peris,
- S J Boyson,
- W A Cass,
- P Curella,
- L P Dwoskin,
- G Larson,
- L H Lin,
- R P Yasuda,
- and N R Zahniser
Persistence of neurochemical changes in dopamine systems after repeated cocaine administration.
J Pharmacol Exp Ther April 1990 253:38-44
- Abstract
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- T H Lin and
- J H Lin
Effects of protein binding and experimental disease states on brain uptake of benzodiazepines in rats.
J Pharmacol Exp Ther April 1990 253:45-50
- Abstract
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- R J Lukas
Heterogeneity of high-affinity nicotinic [3H]acetylcholine binding sites.
J Pharmacol Exp Ther April 1990 253:51-57
- Abstract
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- R A Hahn,
- B R MacDonald,
- P J Simpson,
- B D Potts,
- and C J Parli
Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size.
J Pharmacol Exp Ther April 1990 253:58-66
- Abstract
- Full Text (PDF)
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- K Nishino,
- Y F Su,
- C S Wong,
- W D Watkins,
- and K J Chang
Dissociation of mu opioid tolerance from receptor down-regulation in rat spinal cord.
J Pharmacol Exp Ther April 1990 253:67-72
- Abstract
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- M Iscan and
- M D Maines
Differential regulation of heme and drug metabolism in rat testis and prostate: response to cis-platinum and human chorionic gonadotropin.
J Pharmacol Exp Ther April 1990 253:73-79
- Abstract
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- G J Trachte
Pharmacological differentiation of angiotensin effects in the rabbit isolated vas deferens with dithiothreitol and pertussis toxin.
J Pharmacol Exp Ther April 1990 253:80-84
- Abstract
- Full Text (PDF)
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- W N Shaw,
- C H Mitch,
- J D Leander,
- and D M Zimmerman
Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat.
J Pharmacol Exp Ther April 1990 253:85-89
- Abstract
- Full Text (PDF)
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- M Mistry and
- A Nasjletti
Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats.
J Pharmacol Exp Ther April 1990 253:90-94
- Abstract
- Full Text (PDF)
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- B S Givens and
- G R Breese
Electrophysiological evidence that ethanol alters function of medial septal area without affecting lateral septal function.
J Pharmacol Exp Ther April 1990 253:95-103
- Abstract
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- R Zaczek,
- G Battaglia,
- S Culp,
- N M Appel,
- J F Contrera,
- and E B De Souza
Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data.
J Pharmacol Exp Ther April 1990 253:104-112
- Abstract
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- B D Anderson,
- B L Hoesterey,
- D C Baker,
- and R E Galinsky
Uptake kinetics of 2',3'-dideoxyinosine into brain and cerebrospinal fluid of rats: intravenous infusion studies.
J Pharmacol Exp Ther April 1990 253:113-118
- Abstract
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- D P Brooks,
- L C Contino,
- W Trizna,
- R M Edwards,
- E H Ohlstein,
- and H A Solleveld
Effect of enalapril or the thromboxane receptor antagonist, daltroban, in rats with subtotal renal ablation.
J Pharmacol Exp Ther April 1990 253:119-123
- Abstract
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- T Massamiri and
- S P Duckles
Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses.
J Pharmacol Exp Ther April 1990 253:124-129
- Abstract
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- J J Grigg and
- E G Anderson
Competitive and noncompetitive N-methyl-D-aspartate antagonists modify hypoxia-induced membrane potential changes and protect rat hippocampal slices from functional failure: a quantitative comparison.
J Pharmacol Exp Ther April 1990 253:130-135
- Abstract
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- B I Ghanayem,
- J M Sanders,
- A M Clark,
- J Bailer,
- and H B Matthews
Effects of dose, age, inhibition of metabolism and elimination on the toxicokinetics of 2-butoxyethanol and its metabolites.
J Pharmacol Exp Ther April 1990 253:136-143
- Abstract
- Full Text (PDF)
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- R J Sheldon,
- P J Rivière,
- M E Malarchik,
- H I Moseberg,
- T F Burks,
- and F Porreca
Opioid regulation of mucosal ion transport in the mouse isolated jejunum.
J Pharmacol Exp Ther April 1990 253:144-151
- Abstract
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- R F Kirby and
- A K Johnson
Effects of sympathetic activation on plasma renin activity in the developing rat.
J Pharmacol Exp Ther April 1990 253:152-157
- Abstract
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- D L Barringer and
- R D Buñag
Age-dependent baroreflex attenuation by centrally infused verapamil in rats.
J Pharmacol Exp Ther April 1990 253:158-164
- Abstract
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- H M Vargas and
- B Ringdahl
Centrally active antimuscarinic analogs of oxotremorine selectively block physostigmine-induced hypertension, but not peripheral muscarinic vasodepression.
J Pharmacol Exp Ther April 1990 253:165-170
- Abstract
- Full Text (PDF)
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- U del Balzo,
- I Sakuma,
- and R Levi
Cardiac dysfunction caused by recombinant human C5A anaphylatoxin: mediation by histamine, adenosine and cyclooxygenase arachidonate metabolites.
J Pharmacol Exp Ther April 1990 253:171-179
- Abstract
- Full Text (PDF)
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- W R Rebagay and
- R W Caldwell
Different patterns of autonomic nerve activity produced by a polar vs. a neutral cardiac glycoside.
J Pharmacol Exp Ther April 1990 253:180-184
- Abstract
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- R K Hoover and
- M L Toews
Activation of protein kinase C inhibits internalization and downregulation of muscarinic receptors in 1321N1 human astrocytoma cells.
J Pharmacol Exp Ther April 1990 253:185-191
- Abstract
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- M W Church,
- E L Abel,
- B A Dintcheff,
- and C Matyjasik
Maternal age and blood alcohol concentration in the pregnant Long-Evans rat.
J Pharmacol Exp Ther April 1990 253:192-199
- Abstract
- Full Text (PDF)
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- S Chakder and
- S Rattan
[Tyr0]-calcitonin gene-related peptide 28-37 (rat) as a putative antagonist of calcitonin gene-related peptide responses on opossum internal anal sphincter smooth muscle.
J Pharmacol Exp Ther April 1990 253:200-206
- Abstract
- Full Text (PDF)
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- T Nishimiya,
- H B Daniell,
- J G Webb,
- J Oatis,
- T Walle,
- T E Gaffney,
- and P V Halushka
Chronic treatment with propranolol enhances the synthesis of prostaglandins E2 and I2 by the aorta of spontaneously hypertensive rats.
J Pharmacol Exp Ther April 1990 253:207-213
- Abstract
- Full Text (PDF)
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- V Simonneaux,
- L C Murrin,
- and M Ebadi
Characterization of D1 dopamine receptors in the bovine pineal gland with [3H]SCH 23390.
J Pharmacol Exp Ther April 1990 253:214-220
- Abstract
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- M T Nakada,
- J M Stadel,
- and S T Crooke
Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts.
J Pharmacol Exp Ther April 1990 253:221-229
- Abstract
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- B J Aungst,
- J A Blake,
- N J Rogers,
- and B A Dusak
Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent.
J Pharmacol Exp Ther April 1990 253:230-236
- Abstract
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- N K Mello,
- J H Mendelson,
- S Palmieri,
- B W Lex,
- and S K Teoh
Operant acquisition of alcohol by women.
J Pharmacol Exp Ther April 1990 253:237-245
- Abstract
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- F Amenta,
- A Ricci,
- and J A Vega
Pharmacological characterization of rat renal medulla dopamine-sensitive cyclic adenosine monophosphate generating system.
J Pharmacol Exp Ther April 1990 253:246-249
- Abstract
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- Y Hattori,
- H Nakaya,
- M Endou,
- and M Kanno
Inotropic, electrophysiological and biochemical responses to histamine in rabbit papillary muscles: evidence for coexistence of H1- and H2-receptors.
J Pharmacol Exp Ther April 1990 253:250-256
- Abstract
- Full Text (PDF)
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- C Eva,
- S R Gamalero,
- E Genazzani,
- and E Costa
Molecular mechanisms of homologous desensitization and internalization of muscarinic receptors in primary cultures of neonatal corticostriatal neurons.
J Pharmacol Exp Ther April 1990 253:257-265
- Abstract
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- R L Kline and
- P F Mercer
Contribution of renal nerves to the natriuretic and diuretic effect of alpha-2 adrenergic receptor activation.
J Pharmacol Exp Ther April 1990 253:266-271
- Abstract
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- R Tabrizchi and
- C R Triggle
Comparison between the vasoactive actions of endothelin and arginine vasopressin in pithed rats after pretreatment with BAY K 8644, nifedipine or pertussis toxin.
J Pharmacol Exp Ther April 1990 253:272-276
- Abstract
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- F T van Amsterdam,
- N C Punt,
- M Haas,
- and J Zaagsma
Calcium antagonists show two modes of protection in ischemic heart failure.
J Pharmacol Exp Ther April 1990 253:277-283
- Abstract
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- M Joëls,
- C M Pennartz,
- H Sijbesma,
- and J Schipper
Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus.
J Pharmacol Exp Ther April 1990 253:284-289
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- F L Christofi,
- T J McDonald,
- and M A Cook
Adenosine receptors are coupled negatively to release of tachykinin(s) from enteric nerve endings.
J Pharmacol Exp Ther April 1990 253:290-295
- Abstract
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- M Clergue,
- B Riou,
- and Y Lecarpentier
Inotropic and lusitropic effects of chlorpromazine on rat left ventricular papillary muscle.
J Pharmacol Exp Ther April 1990 253:296-304
- Abstract
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- S Urien,
- R Zini,
- M Lemaire,
- and J P Tillement
Assessment of cyclosporine A interactions with human plasma lipoproteins in vitro and in vivo in the rat.
J Pharmacol Exp Ther April 1990 253:305-309
- Abstract
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- R Micheletti and
- A Schiavone
Functional determination of McN-A-343 affinity for M1 muscarinic receptors.
J Pharmacol Exp Ther April 1990 253:310-314
- Abstract
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- A Tsuji,
- T Terasaki,
- I Tamai,
- and K Takeda
In vivo evidence for carrier-mediated uptake of beta-lactam antibiotics through organic anion transport systems in rat kidney and liver.
J Pharmacol Exp Ther April 1990 253:315-320
- Abstract
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- B Ferrier,
- M Martin,
- and G Baverel
Effect of lithium on renal transport and utilization of alpha-ketoglutarate in the rat.
J Pharmacol Exp Ther April 1990 253:321-327
- Abstract
- Full Text (PDF)
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- A López-Farré,
- F Bernabeu,
- D Gómez-Garre,
- S Ramon y Cajal,
- P Braquet,
- and J M López-Novoa
Platelet-activating factor antagonists treatment protects against postischemic acute renal failure in rats.
J Pharmacol Exp Ther April 1990 253:328-333
- Abstract
- Full Text (PDF)
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- D N Stephens,
- H H Schneider,
- W Kehr,
- J S Andrews,
- K J Rettig,
- L Turski,
- R Schmiechen,
- J D Turner,
- L H Jensen,
- and E N Petersen
Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.
J Pharmacol Exp Ther April 1990 253:334-343
- Abstract
- Full Text (PDF)
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- L Turski,
- D N Stephens,
- L H Jensen,
- E N Petersen,
- B S Meldrum,
- S Patel,
- J B Hansen,
- W Löscher,
- H H Schneider,
- and R Schmiechen
Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio.
J Pharmacol Exp Ther April 1990 253:344-352
- Abstract
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- M Nayebpour,
- M Talajic,
- W Jing,
- and S Nattel
Autonomic modulation of the frequency-dependent actions of diltiazem on the atrioventricular node in anesthetized dogs.
J Pharmacol Exp Ther April 1990 253:353-361
- Abstract
- Full Text (PDF)
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- F H Noormohamed,
- W R McNabb,
- and A F Lant
Pharmacokinetic and pharmacodynamic actions of enalapril in humans: effect of probenecid pretreatment.
J Pharmacol Exp Ther April 1990 253:362-368
- Abstract
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- S Fujita,
- M Chiba,
- M Ohta,
- K Kitani,
- and T Suzuki
Alteration of plasma sex hormone levels associated with old age and its effect on hepatic drug metabolism in rats.
J Pharmacol Exp Ther April 1990 253:369-374
- Abstract
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- M J Stevens and
- R F Moulds
Alpha adrenoceptor activation and postreceptor contractile mechanisms in the human digital artery.
J Pharmacol Exp Ther April 1990 253:375-380
- Abstract
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- J Black,
- L Diment,
- C Armour,
- L Alouan,
- and P Johnson
Distribution of substance P receptors in rabbit airways, functional and autoradiographic studies.
J Pharmacol Exp Ther April 1990 253:381-386
- Abstract
- Full Text (PDF)
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- I de Waziers,
- P H Cugnenc,
- C S Yang,
- J P Leroux,
- and P H Beaune
Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.
J Pharmacol Exp Ther April 1990 253:387-394
- Abstract
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- M G Lacey,
- P Calabresi,
- and R A North
Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors.
J Pharmacol Exp Ther April 1990 253:395-400
- Abstract
- Full Text (PDF)
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- A K Louie,
- E S Bass,
- J Zhan,
- P Y Law,
- and H H Loh
Attenuation of opioid receptor activity by phorbol esters in neuroblastoma x glioma NG108-15 hybrid cells.
J Pharmacol Exp Ther April 1990 253:401-407
- Abstract
- Full Text (PDF)
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- P Ernsberger,
- R Giuliano,
- R N Willette,
- and D J Reis
Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla.
J Pharmacol Exp Ther April 1990 253:408-418
- Abstract
- Full Text (PDF)
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- A N Schoffelmeer,
- Y H Yao,
- T L Gioannini,
- J M Hiller,
- D Ofri,
- B P Roques,
- and E J Simon
Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex.
J Pharmacol Exp Ther April 1990 253:419-426
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

On the mechanism of the different sensitivity of Purkinje and myocardial fibers to strophanthidin.

The interaction of amitriptyline, doxepin, imipramine and their N-methyl quaternary ammonium derivatives with subtypes of muscarinic receptors in brain and heart.

Endothelial nitric oxide generating enzyme(s) in the bovine aorta: subcellular location and metabolic characterization.

Histamine and methacholine aerosol bronchial challenge in awake guinea pigs.

Mechanisms of amphotericin B-induced reduction of the glomerular filtration rate: a micropuncture study.

Persistence of neurochemical changes in dopamine systems after repeated cocaine administration.

Effects of protein binding and experimental disease states on brain uptake of benzodiazepines in rats.

Heterogeneity of high-affinity nicotinic [3H]acetylcholine binding sites.

Antagonism of leukotriene B4 receptors does not limit canine myocardial infarct size.

Dissociation of mu opioid tolerance from receptor down-regulation in rat spinal cord.

Differential regulation of heme and drug metabolism in rat testis and prostate: response to cis-platinum and human chorionic gonadotropin.

Pharmacological differentiation of angiotensin effects in the rabbit isolated vas deferens with dithiothreitol and pertussis toxin.

Effect of phenylpiperidine opioid antagonists on food consumption and weight gain of the obese Zucker rat.

Contrasting effect of thromboxane synthase inhibitors and a thromboxane receptor antagonist on the development of angiotensin II-salt-induced hypertension in rats.

Electrophysiological evidence that ethanol alters function of medial septal area without affecting lateral septal function.

Effects of repeated fenfluramine administration on indices of monoamine function in rat brain: pharmacokinetic, dose response, regional specificity and time course data.

Uptake kinetics of 2',3'-dideoxyinosine into brain and cerebrospinal fluid of rats: intravenous infusion studies.

Effect of enalapril or the thromboxane receptor antagonist, daltroban, in rats with subtotal renal ablation.

Multiple vascular effects of sigma and PCP ligands: inhibition of amine uptake and contractile responses.

Competitive and noncompetitive N-methyl-D-aspartate antagonists modify hypoxia-induced membrane potential changes and protect rat hippocampal slices from functional failure: a quantitative comparison.

Effects of dose, age, inhibition of metabolism and elimination on the toxicokinetics of 2-butoxyethanol and its metabolites.

Opioid regulation of mucosal ion transport in the mouse isolated jejunum.

Effects of sympathetic activation on plasma renin activity in the developing rat.

Age-dependent baroreflex attenuation by centrally infused verapamil in rats.

Centrally active antimuscarinic analogs of oxotremorine selectively block physostigmine-induced hypertension, but not peripheral muscarinic vasodepression.

Cardiac dysfunction caused by recombinant human C5A anaphylatoxin: mediation by histamine, adenosine and cyclooxygenase arachidonate metabolites.

Different patterns of autonomic nerve activity produced by a polar vs. a neutral cardiac glycoside.

Activation of protein kinase C inhibits internalization and downregulation of muscarinic receptors in 1321N1 human astrocytoma cells.

Maternal age and blood alcohol concentration in the pregnant Long-Evans rat.

[Tyr0]-calcitonin gene-related peptide 28-37 (rat) as a putative antagonist of calcitonin gene-related peptide responses on opossum internal anal sphincter smooth muscle.

Chronic treatment with propranolol enhances the synthesis of prostaglandins E2 and I2 by the aorta of spontaneously hypertensive rats.

Characterization of D1 dopamine receptors in the bovine pineal gland with [3H]SCH 23390.

Subtype-selective regulation of beta adrenergic receptor-adenylyl cyclase coupling by phorbol esters in 3T3-L1 fibroblasts.

Effects of plasma protein binding displacement on the pharmacokinetics, tissue and tumor concentrations and efficacy of brequinar, a highly protein-bound antitumor agent.

Operant acquisition of alcohol by women.

Pharmacological characterization of rat renal medulla dopamine-sensitive cyclic adenosine monophosphate generating system.

Inotropic, electrophysiological and biochemical responses to histamine in rabbit papillary muscles: evidence for coexistence of H1- and H2-receptors.

Molecular mechanisms of homologous desensitization and internalization of muscarinic receptors in primary cultures of neonatal corticostriatal neurons.

Contribution of renal nerves to the natriuretic and diuretic effect of alpha-2 adrenergic receptor activation.

Comparison between the vasoactive actions of endothelin and arginine vasopressin in pithed rats after pretreatment with BAY K 8644, nifedipine or pertussis toxin.

Calcium antagonists show two modes of protection in ischemic heart failure.

Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus.

Adenosine receptors are coupled negatively to release of tachykinin(s) from enteric nerve endings.

Inotropic and lusitropic effects of chlorpromazine on rat left ventricular papillary muscle.

Assessment of cyclosporine A interactions with human plasma lipoproteins in vitro and in vivo in the rat.

Functional determination of McN-A-343 affinity for M1 muscarinic receptors.

In vivo evidence for carrier-mediated uptake of beta-lactam antibiotics through organic anion transport systems in rat kidney and liver.

Effect of lithium on renal transport and utilization of alpha-ketoglutarate in the rat.

Platelet-activating factor antagonists treatment protects against postischemic acute renal failure in rats.

Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.

Anticonvulsant action of the beta-carboline abecarnil: studies in rodents and baboon, Papio papio.

Autonomic modulation of the frequency-dependent actions of diltiazem on the atrioventricular node in anesthetized dogs.

Pharmacokinetic and pharmacodynamic actions of enalapril in humans: effect of probenecid pretreatment.

Alteration of plasma sex hormone levels associated with old age and its effect on hepatic drug metabolism in rats.

Alpha adrenoceptor activation and postreceptor contractile mechanisms in the human digital artery.

Distribution of substance P receptors in rabbit airways, functional and autoradiographic studies.

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

Muscarine depolarizes rat substantia nigra zona compacta and ventral tegmental neurons in vitro through M1-like receptors.

Attenuation of opioid receptor activity by phorbol esters in neuroblastoma x glioma NG108-15 hybrid cells.

Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla.

Cross-linking of human [125I]beta-endorphin to opioid receptors in rat striatal membranes: biochemical evidence for the existence of a mu/delta opioid receptor complex.

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