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Table of Contents
December 1989; 251 (3)
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Y Furukawa
,
D W Wallick
,
and
P Martin
Differential blocking effects of atropine and gallamine on negative chronotropic and dromotropic responses to vagus stimulation in anesthetized dogs.
J Pharmacol Exp Ther
December 1989
251
:
797
-
802
Abstract
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P Blandina
,
J Goldfarb
,
B Craddock-Royal
,
and
J P Green
Release of endogenous dopamine by stimulation of 5-hydroxytryptamine3 receptors in rat striatum.
J Pharmacol Exp Ther
December 1989
251
:
803
-
809
Abstract
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E G Henderson
,
D J Post-Munson
,
L S Reynolds
,
and
P M Epstein
Echothiophate and cogeners decrease the voltage dependence of end-plate current decay in frog skeletal muscle.
J Pharmacol Exp Ther
December 1989
251
:
810
-
816
Abstract
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H Ishida
,
A G Scicli
,
and
O A Carretero
Contributions of various rat plasma peptidases to kinin hydrolysis.
J Pharmacol Exp Ther
December 1989
251
:
817
-
820
Abstract
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W M Pardridge
,
D Triguero
,
and
J Buciak
Transport of histone through the blood-brain barrier.
J Pharmacol Exp Ther
December 1989
251
:
821
-
826
Abstract
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J G Zhi
and
G Levy
Kinetics of drug action in disease states. XXXVII. Effects of acute fluid overload and water deprivation on the hypnotic activity of phenobarbital and the neurotoxicity of theophylline in rats.
J Pharmacol Exp Ther
December 1989
251
:
827
-
832
Abstract
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D J Henry
,
M A Greene
,
and
F J White
Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration.
J Pharmacol Exp Ther
December 1989
251
:
833
-
839
Abstract
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D H Bobker
,
K Z Shen
,
A Surprenant
,
and
J T Williams
DTG and (+)-3-PPP inhibit a ligand-activated hyperpolarization in mammalian neurons.
J Pharmacol Exp Ther
December 1989
251
:
840
-
845
Abstract
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C A Catanese
,
R C Falcone
,
and
D Aharony
Guanyl-5'-yl-lmidodiphosphate regulation of ligand binding to LTD4 receptors on guinea pig lung membranes.
J Pharmacol Exp Ther
December 1989
251
:
846
-
851
Abstract
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H Q Vu
,
D Budai
,
and
S P Duckles
Neuropeptide Y preferentially potentiates responses to adrenergic nerve stimulation by increasing rate of contraction.
J Pharmacol Exp Ther
December 1989
251
:
852
-
857
Abstract
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E K Jackson
,
W A Herzer
,
and
J A Lawson
Defective modulation of noradrenergic neurotransmission by exogenous prostaglandins in aging spontaneously hypertensive rats.
J Pharmacol Exp Ther
December 1989
251
:
858
-
869
Abstract
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R E Hampson
,
T C Foster
,
and
S A Deadwyler
Effects of delta-9-tetrahydrocannabinol on sensory evoked hippocampal activity in the rat: principal components analysis and sequential dependency.
J Pharmacol Exp Ther
December 1989
251
:
870
-
877
Abstract
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M T Piascik
,
B T Butler
,
J W Kusiak
,
J Pitha
,
and
J R Holtman, Jr
Effect of an alkylating analog of prazosin on alpha-1 adrenoceptor subtypes and arterial blood pressure.
J Pharmacol Exp Ther
December 1989
251
:
878
-
883
Abstract
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Y Vulliemoz
and
M Verosky
Effect of clonidine on myocardial cyclic GMP content in the mouse-activation of central and peripheral alpha adrenoceptors.
J Pharmacol Exp Ther
December 1989
251
:
884
-
887
Abstract
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M F Jarvis
,
R Schulz
,
A J Hutchison
,
U H Do
,
M A Sills
,
and
M Williams
[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.
J Pharmacol Exp Ther
December 1989
251
:
888
-
893
Abstract
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H A Navarro
,
F J Seidler
,
J P Eylers
,
F E Baker
,
S S Dobbins
,
S E Lappi
,
and
T A Slotkin
Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain.
J Pharmacol Exp Ther
December 1989
251
:
894
-
900
Abstract
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L A Matsuda
,
G R Hanson
,
and
J W Gibb
Neurochemical effects of amphetamine metabolites on central dopaminergic and serotonergic systems.
J Pharmacol Exp Ther
December 1989
251
:
901
-
908
Abstract
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P Li
and
E K Jackson
Enhanced slow-pressor response to angiotensin II in spontaneously hypertensive rats.
J Pharmacol Exp Ther
December 1989
251
:
909
-
921
Abstract
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G T Somogyi
and
J M Perel
Antagonism by tricyclic antidepressants of the muscarinic receptors located on the adrenergic nerve endings in rabbit heart atrium.
J Pharmacol Exp Ther
December 1989
251
:
922
-
928
Abstract
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C Hoegler
,
J McIntyre
,
G Zeballos
,
J Shapiro
,
M DeLeonardis
,
P Needleman
,
and
T Hintze
Relationship between plasma atriopeptin concentration and function in the conscious primate.
J Pharmacol Exp Ther
December 1989
251
:
929
-
936
Abstract
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P P Sokol
,
K R Huiatt
,
P D Holohan
,
and
C R Ross
Gentamicin and verapamil compete for a common transport mechanism in renal brush border membrane vesicles.
J Pharmacol Exp Ther
December 1989
251
:
937
-
942
Abstract
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M H Sabouni
,
D J Cushing
,
and
S J Mustafa
Adenosine receptor-mediated relaxation in coronary artery: evidence for a guanyl nucleotide-binding regulatory protein involvement.
J Pharmacol Exp Ther
December 1989
251
:
943
-
948
Abstract
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D D Christ
and
T Walle
Stereoselective sulfation of R,S-4'-hydroxypropranolol by canine hepatic cytosol and partially purified phenolsulfotransferases.
J Pharmacol Exp Ther
December 1989
251
:
949
-
955
Abstract
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P P Tamburini
,
J A Koehn
,
J P Gilligan
,
D Charles
,
R A Palmesino
,
R Sharif
,
C McMartin
,
M D Erion
,
and
M J Miller
Rat vascular tissue contains a neutral endopeptidase capable of degrading atrial natriuretic peptide.
J Pharmacol Exp Ther
December 1989
251
:
956
-
961
Abstract
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J C Gordon
,
D S Barefoot
,
N S Sarbin
,
and
L M Pinkus
[3H]zacopride binding to 5-hydroxytryptamine3 sites on partially purified rabbit enteric neuronal membranes.
J Pharmacol Exp Ther
December 1989
251
:
962
-
968
Abstract
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C B Jin
and
R W Rockhold
Effects of paraventricular hypothalamic microinfusions of kainic acid on cardiovascular and renal excretory function in conscious rats.
J Pharmacol Exp Ther
December 1989
251
:
969
-
975
Abstract
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W B Pickworth
,
R I Herning
,
and
J E Henningfield
Spontaneous EEG changes during tobacco abstinence and nicotine substitution in human volunteers.
J Pharmacol Exp Ther
December 1989
251
:
976
-
982
Abstract
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L Carpenter-Deyo
and
R A Roth
Cyclooxygenase inhibition in lungs or in neutrophils attenuates neutrophil-dependent edema in rat lungs perfused with phorbol myristate acetate.
J Pharmacol Exp Ther
December 1989
251
:
983
-
991
Abstract
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N H Lee
,
A D Fryer
,
C Forray
,
and
E E el-Fakahany
Different mechanisms of antagonism by methoctramine of two neuronal muscarinic receptor-mediated second messenger responses.
J Pharmacol Exp Ther
December 1989
251
:
992
-
999
Abstract
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E G McMahon
,
M A Palomo
,
P Mehta
,
and
G M Olins
Depressor and natriuretic effects of M&B 22,948, a guanosine cyclic 3',5'-monophosphate-selective phosphodiesterase inhibitor.
J Pharmacol Exp Ther
December 1989
251
:
1000
-
1005
Abstract
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M L Cohen
,
C J Parli
,
and
R W Fuller
5-Hydroxytryptamine2 receptor antagonist activity of the acid metabolite (1-isopropyl dihydrolysergic acid) of the ergoline ester, sergolexole (LY281067).
J Pharmacol Exp Ther
December 1989
251
:
1006
-
1011
Abstract
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W M Armstead
,
R Mirro
,
D W Busija
,
and
C W Leffler
Permissive role of prostanoids in acetylcholine-induced cerebral vasoconstriction.
J Pharmacol Exp Ther
December 1989
251
:
1012
-
1019
Abstract
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G J Grover
,
C S Parham
,
P G Sleph
,
and
S Moreland
Anti-ischemic and vasorelaxant effects of the new benzazepine calcium channel blocker SQ 31,765.
J Pharmacol Exp Ther
December 1989
251
:
1020
-
1025
Abstract
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G S Sedek
,
T I Ruo
,
M C Frederiksen
,
J W Frederiksen
,
S R Shih
,
and
A J Atkinson, Jr
Splanchnic tissues are a major part of the rapid distribution spaces of inulin, urea and theophylline.
J Pharmacol Exp Ther
December 1989
251
:
1026
-
1031
Abstract
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J B Schwartz
,
D Verotta
,
and
L B Sheiner
Pharmacodynamic modeling of verapamil effects under steady-state and nonsteady-state conditions.
J Pharmacol Exp Ther
December 1989
251
:
1032
-
1038
Abstract
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T W Vickroy
and
E D Cadman
Dissociation between muscarinic receptor-mediated inhibition of adenylate cyclase and autoreceptor inhibition of [3H] acetylcholine release in rat hippocampus.
J Pharmacol Exp Ther
December 1989
251
:
1039
-
1044
Abstract
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J M Fujimoto
and
J J Rady
Intracerebroventricular physostigmine-induced analgesia: enhancement by naloxone, beta-funaltrexamine and nor-binaltorphimine and antagonism by dynorphin A (1-17).
J Pharmacol Exp Ther
December 1989
251
:
1045
-
1052
Abstract
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W K Bickel
,
G E Bigelow
,
K L Preston
,
and
I A Liebson
Opioid drug discrimination in humans: stability, specificity and relation to self-reported drug effect.
J Pharmacol Exp Ther
December 1989
251
:
1053
-
1063
Abstract
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C S Hornfeldt
and
A A Larson
Selective inhibition of excitatory amino acids by divalent cations. A novel means for distinguishing N-methyl-D-aspartic acid-, kainate- and quisqualate-mediated actions in the mouse spinal cord.
J Pharmacol Exp Ther
December 1989
251
:
1064
-
1068
Abstract
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N Ballatori
and
A T Truong
Altered hepatic junctional permeability, bile acid excretion and glutathione efflux during oxidant challenge.
J Pharmacol Exp Ther
December 1989
251
:
1069
-
1075
Abstract
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J N Stallone
,
H Nishimura
,
and
M C Khosla
Angiotensin II vascular receptors in fowl aorta: binding specificity and modulation by divalent cations and guanine nucleotides.
J Pharmacol Exp Ther
December 1989
251
:
1076
-
1082
Abstract
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H Takayama
,
M D Majewska
,
and
E D London
Interactions of noncompetitive inhibitors with nicotinic receptors in the rat brain.
J Pharmacol Exp Ther
December 1989
251
:
1083
-
1089
Abstract
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G E DeLander
and
J J Wahl
Morphine (intracerebroventricular) activates spinal systems to inhibit behavior induced by putative pain neurotransmitters.
J Pharmacol Exp Ther
December 1989
251
:
1090
-
1095
Abstract
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J A Kiritsy-Roy
,
L Marson
,
and
G R Van Loon
Sympathoadrenal, cardiovascular and blood gas responses to highly selective mu and delta opioid peptides.
J Pharmacol Exp Ther
December 1989
251
:
1096
-
1103
Abstract
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K L Marquis
,
N C Paquette
,
R P Gussio
,
and
J E Moreton
Comparative electroencephalographic and behavioral effects of phencyclidine, (+)-SKF-10,047 and MK-801 in rats.
J Pharmacol Exp Ther
December 1989
251
:
1104
-
1112
Abstract
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D M Ackerman
,
M M Brady
,
A G MacLean
,
and
T M Smith
AY-31,906, a novel high ceiling diuretic: characterization of its relative potassium-sparing actions in rats and dogs.
J Pharmacol Exp Ther
December 1989
251
:
1113
-
1119
Abstract
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R Kafiluddi
,
R H Kennedy
,
and
E Seifen
Extracellular magnesium and cardiotonic steroid toxicity in isolated myocardial preparations.
J Pharmacol Exp Ther
December 1989
251
:
1120
-
1127
Abstract
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C F Uyehara
,
S Caltabiano
,
L B Kinter
,
and
M Gellai
Noncyclic vasopressin analogs are effective diuretics in conscious rats.
J Pharmacol Exp Ther
December 1989
251
:
1128
-
1133
Abstract
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H D Allescher
,
E E Daniel
,
J E Fox
,
F Kostolanska
,
and
L A Rovati
Effect of the novel cholecystokinin receptor antagonist CR-1392 on cholecystokinin-induced antroduodenal and pyloric motor activity in vivo.
J Pharmacol Exp Ther
December 1989
251
:
1134
-
1141
Abstract
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G Maura
,
R Carbone
,
and
M Raiteri
Aspartate-releasing nerve terminals in rat striatum possess D-2 dopamine receptors mediating inhibition of release.
J Pharmacol Exp Ther
December 1989
251
:
1142
-
1146
Abstract
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G R Bolt
,
H Itoh
,
K Lederis
,
and
K L MacCannell
Differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated vasoconstrictor responses by a vasodilator peptide, urotensin I: comparison with nifedipine.
J Pharmacol Exp Ther
December 1989
251
:
1147
-
1154
Abstract
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A Miyanoshita
,
M Terada
,
and
H Endou
Furosemide directly stimulates prostaglandin E2 production in the thick ascending limb of Henle's loop.
J Pharmacol Exp Ther
December 1989
251
:
1155
-
1159
Abstract
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R K Talmaciu
,
I S Hoffmann
,
and
L X Cubeddu
Differential effects of phorbol ester on prefrontal cortex and striatal dopamine terminals: dependence on rate and duration of stimulation.
J Pharmacol Exp Ther
December 1989
251
:
1160
-
1165
Abstract
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S Abraham
,
G N Beatch
,
B A MacLeod
,
and
M J Walker
Antiarrhythmic properties of tetrodotoxin against occlusion-induced arrhythmias in the rat: a novel approach to the study of the antiarrhythmic effects of ventricular sodium channel blockade.
J Pharmacol Exp Ther
December 1989
251
:
1166
-
1173
Abstract
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H Kai
,
H Kanaide
,
and
M Nakamura
Effects of nicorandil on cytosolic calcium concentrations in quin2-loaded rat aortic vascular smooth muscle cells in primary culture.
J Pharmacol Exp Ther
December 1989
251
:
1174
-
1180
Abstract
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W Endres
,
A Spuler
,
and
G ten Bruggencate
Acetylcholinesterase reactivators antagonize epileptiform bursting induced by paraoxon in guinea pig hippocampal slices.
J Pharmacol Exp Ther
December 1989
251
:
1181
-
1186
Abstract
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J S Saulnier-Blache
,
M Taouis
,
M Dauzats
,
A Uzan
,
M Berlan
,
and
M Lafontan
Lipolytic action of a new alpha-2 adrenergic antagonist of the piperazinopyrimidine family: RP 55462.
J Pharmacol Exp Ther
December 1989
251
:
1187
-
1192
Abstract
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J S Saulnier-Blache
,
M Taouis
,
M Dauzats
,
A Uzan
,
M Berlan
,
and
M Lafontan
Mechanism of lipolytic action of a new alpha-2 adrenergic antagonist of the piperazinopyrimidine family: RP 55462.
J Pharmacol Exp Ther
December 1989
251
:
1193
-
1198
Abstract
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H Tanaka
,
Y Okada
,
M Kawagishi
,
and
T Tokiwa
Pharmacokinetics and pharmacodynamics of recombinant human granulocyte-colony stimulating factor after intravenous and subcutaneous administration in the rat.
J Pharmacol Exp Ther
December 1989
251
:
1199
-
1203
Abstract
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S F Liu
,
D G McCormack
,
T W Evans
,
and
P J Barnes
Characterization and distribution of P2-purinoceptor subtypes in rat pulmonary vessels.
J Pharmacol Exp Ther
December 1989
251
:
1204
-
1210
Abstract
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I A de Lannoy
,
R Nespeca
,
and
K S Pang
Renal handling of enalapril and enalaprilat: studies in the isolated red blood cell-perfused rat kidney.
J Pharmacol Exp Ther
December 1989
251
:
1211
-
1222
Abstract
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L I Simpson
The binary toxin produced by Clostridium botulinum enters cells by receptor-mediated endocytosis to exert its pharmacologic effects.
J Pharmacol Exp Ther
December 1989
251
:
1223
-
1228
Abstract
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P H Franklin
,
G Zhang
,
E D Tripp
,
and
T F Murray
Adenosine A1 receptor activation mediates suppression of (-) bicuculline methiodide-induced seizures in rat prepiriform cortex.
J Pharmacol Exp Ther
December 1989
251
:
1229
-
1236
Abstract
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S S Hedge
,
A Ricci
,
F Amenta
,
and
M F Lokhandwala
Evidence from functional and autoradiographic studies for the presence of tubular dopamine-1 receptors and their involvement in the renal effects of fenoldopam.
J Pharmacol Exp Ther
December 1989
251
:
1237
-
1245
Abstract
Full Text (PDF)
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