Table of Contents

November 1989; 251 (2)

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- R Rozental,
- Y Aracava,
- G T Scoble,
- K L Swanson,
- S Wonnacott,
- and E X Albuquerque
Agonist recognition site of the peripheral acetylcholine receptor ion channel complex differentiates the enantiomers of nicotine.
J Pharmacol Exp Ther November 1989 251:395-404
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- T L Wimpey,
- K E Opheim,
- and C Chavkin
Effects of chronic morphine administration on the mu and delta opioid responses in the CA1 region of the rat hippocampus.
J Pharmacol Exp Ther November 1989 251:405-411
- Abstract
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- E T Iwamoto
Antinociception after nicotine administration into the mesopontine tegmentum of rats: evidence for muscarinic actions.
J Pharmacol Exp Ther November 1989 251:412-421
- Abstract
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- E M Hull,
- R K Warner,
- T J Bazzett,
- R C Eaton,
- J T Thompson,
- and L L Scaletta
D2/D1 ratio in the medial preoptic area affects copulation of male rats.
J Pharmacol Exp Ther November 1989 251:422-427
- Abstract
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- L D Van de Kar,
- M Carnes,
- R J Maslowski,
- A M Bonadonna,
- P A Rittenhouse,
- K Kunimoto,
- R A Piechowski,
- and C L Bethea
Neuroendocrine evidence for denervation supersensitivity of serotonin receptors: effects of the 5-HT agonist RU 24969 on corticotropin, corticosterone, prolactin and renin secretion.
J Pharmacol Exp Ther November 1989 251:428-434
- Abstract
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- R L Kleiman-Wexler,
- C G Adair,
- and K S Ephgrave
Pharmacokinetics of naloxone: an insight into the locus of effect on stress-ulceration.
J Pharmacol Exp Ther November 1989 251:435-438
- Abstract
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- A Lasdun,
- S Reznik,
- C J Molineaux,
- and M Orlowski
Inhibition of endopeptidase 24.15 slows the in vivo degradation of luteinizing hormone-releasing hormone.
J Pharmacol Exp Ther November 1989 251:439-447
- Abstract
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- I Y Hwang and
- A A Elfarra
Cysteine S-conjugates may act as kidney-selective prodrugs: formation of 6-mercaptopurine by the renal metabolism of S-(6-purinyl)-L-cysteine.
J Pharmacol Exp Ther November 1989 251:448-454
- Abstract
- Full Text (PDF)
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- A J Bertalmio and
- J H Woods
Reinforcing effect of alfentanil is mediated by mu opioid receptors: apparent pA2 analysis.
J Pharmacol Exp Ther November 1989 251:455-460
- Abstract
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- J A Clark,
- L Liu,
- M Price,
- B Hersh,
- M Edelson,
- and G W Pasternak
Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.
J Pharmacol Exp Ther November 1989 251:461-468
- Abstract
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- M A Gistrak,
- D Paul,
- E F Hahn,
- and G W Pasternak
Pharmacological actions of a novel mixed opiate agonist/antagonist: naloxone benzoylhydrazone.
J Pharmacol Exp Ther November 1989 251:469-476
- Abstract
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- D Paul,
- K M Standifer,
- C E Inturrisi,
- and G W Pasternak
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.
J Pharmacol Exp Ther November 1989 251:477-483
- Abstract
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- E Elton,
- D C Chiossone,
- G P McCafferty,
- F M Ryan,
- and P L Smith
SK&F 104353: selective antagonism of peptidoleukotrine-induced changes in electrolyte transport by rat ileal mucosa in vitro.
J Pharmacol Exp Ther November 1989 251:484-489
- Abstract
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- S Trivedi,
- I I Kaiser,
- M Tanaka,
- and L L Simpson
Pharmacologic experiments on the interaction between crotoxin and the mammalian neuromuscular junction.
J Pharmacol Exp Ther November 1989 251:490-496
- Abstract
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- D Budai and
- S P Duckles
Opioid-induced prejunctional inhibition of vasoconstriction in the rabbit ear artery: alpha-2 adrenoceptor activation and external calcium.
J Pharmacol Exp Ther November 1989 251:497-501
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- K M Harnett,
- C T Walsh,
- and L H Zhang
Effects of Bay o 2752, a hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification.
J Pharmacol Exp Ther November 1989 251:502-509
- Abstract
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- K Raynor and
- T Reisine
Analogs of somatostatin selectively label distinct subtypes of somatostatin receptors in rat brain.
J Pharmacol Exp Ther November 1989 251:510-517
- Abstract
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- H E Shannon and
- B D Sawyer
Glutamate receptors of the N-methyl-D-aspartate subtype in the myenteric plexus of the guinea pig ileum.
J Pharmacol Exp Ther November 1989 251:518-523
- Abstract
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- R L Stephens,
- T Garrick,
- H Weiner,
- and Y Taché
Serotonin depletion potentiates gastric secretory and motor responses to vagal but not peripheral gastric stimulants.
J Pharmacol Exp Ther November 1989 251:524-530
- Abstract
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- S H Burstein,
- C A Audette,
- S A Doyle,
- K Hull,
- S A Hunter,
- and V Latham
Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid.
J Pharmacol Exp Ther November 1989 251:531-535
- Abstract
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- A M Moudy,
- C J Coscia,
- and M B Laskowski
A mu-specific opioid peptide agonist increases excitability of pyramidal neurons in untreated and receptor up-regulated hippocampus.
J Pharmacol Exp Ther November 1989 251:536-542
- Abstract
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- W Surichamorn,
- E A Abdallah,
- and E E el-Fakahany
Aging does not alter brain muscarinic receptor-mediated phosphoinositide hydrolysis and its inhibition by phorbol esters, tetrodotoxin and receptor desensitization.
J Pharmacol Exp Ther November 1989 251:543-549
- Abstract
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- J G Gerber and
- P H Guth
Role of adenosine in the gastric blood flow response to pentagastrin in the rat.
J Pharmacol Exp Ther November 1989 251:550-556
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- T A Morinelli,
- J E Oatis, Jr,
- A K Okwu,
- D E Mais,
- P R Mayeux,
- A Masuda,
- D R Knapp,
- and P V Halushka
Characterization of an 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist.
J Pharmacol Exp Ther November 1989 251:557-562
- Abstract
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- A K Mandal,
- K J Kellar,
- E Friedman,
- S V Pineo,
- P Hamosh,
- and R A Gillis
Importance of central nervous system serotonin-1A receptors for mediating the hypotensive effect of urapidil.
J Pharmacol Exp Ther November 1989 251:563-570
- Abstract
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- A C Uprichard,
- L G Chi,
- J M Kitzen,
- J J Lynch,
- J W Frye,
- and B R Lucchesi
Celiprolol does not protect against ventricular tachycardia or sudden death in the conscious canine: a comparison with pindolol in assessing the role of intrinsic sympathomimetic activity.
J Pharmacol Exp Ther November 1989 251:571-577
- Abstract
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- K M Baker,
- H A Singer,
- and J F Aceto
Angiotensin II receptor-mediated stimulation of cytosolic-free calcium and inositol phosphates in chick myocytes.
J Pharmacol Exp Ther November 1989 251:578-585
- Abstract
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- L Noronha-Blob,
- V C Lowe,
- J S Peterson,
- and R C Hanson
The anticholinergic activity of agents indicated for urinary incontinence is an important property for effective control of bladder dysfunction.
J Pharmacol Exp Ther November 1989 251:586-593
- Abstract
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- E K Hong and
- A E Takemori
Indirect involvement of delta opioid receptors in cholecystokinin octapeptide-induced analgesia in mice.
J Pharmacol Exp Ther November 1989 251:594-598
- Abstract
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- C R Bowden and
- C S Marchione
Effects of nebivolol, atenolol and propranolol on in vivo cardiovascular and metabolic responses to isoproterenol in dogs.
J Pharmacol Exp Ther November 1989 251:599-605
- Abstract
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- H G Meyer,
- B J Lukey,
- R T Gepp,
- M P McCluskey,
- and C N Lieske
Development and application of a radioimmunoassay for physostigmine.
J Pharmacol Exp Ther November 1989 251:606-611
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- R J Mandel,
- A D Chen,
- D J Connor,
- and L J Thal
Continuous physostigmine infusion in rats with excitotoxic lesions of the nucleus basalis magnocellularis: effects on performance in the water maze task and cortical cholinergic markers.
J Pharmacol Exp Ther November 1989 251:612-619
- Abstract
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- R Kraemer and
- K M Mullane
Neutrophils delay functional recovery of the post-hypoxic heart of the rabbit.
J Pharmacol Exp Ther November 1989 251:620-626
- Abstract
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- J Willetts and
- R L Balster
Effects of competitive and noncompetitive N-methyl-D-aspartate (NMDA) antagonists in rats trained to discriminate NMDA from saline.
J Pharmacol Exp Ther November 1989 251:627-633
- Abstract
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- E Sehic and
- K U Malik
Influence of protein kinase C activators on vascular tone and adrenergic neuroeffector events in the isolated rat kidney.
J Pharmacol Exp Ther November 1989 251:634-639
- Abstract
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- D B Bylund and
- C Ray-Prenger
Alpha-2A and alpha-2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype.
J Pharmacol Exp Ther November 1989 251:640-644
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- L Kerecsen and
- R D Bunag
Selective pressor enhancement by monoamine oxidase inhibitors in conscious rats.
J Pharmacol Exp Ther November 1989 251:645-649
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- M Nishimura,
- C H Follmer,
- and D H Singer
Amiodarone blocks calcium current in single guinea pig ventricular myocytes.
J Pharmacol Exp Ther November 1989 251:650-659
- Abstract
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- F J Ehlert,
- F M Delen,
- S H Yun,
- D J Friedman,
- and D W Self
Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart.
J Pharmacol Exp Ther November 1989 251:660-671
- Abstract
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- W D Atchison
Dihydropyridine-sensitive and -insensitive components of acetylcholine release from rat motor nerve terminals.
J Pharmacol Exp Ther November 1989 251:672-678
- Abstract
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- M E Maragoudakis,
- M Sarmonika,
- and M Panoutsacopoulou
Antiangiogenic action of heparin plus cortisone is associated with decreased collagenous protein synthesis in the chick chorioallantoic membrane system.
J Pharmacol Exp Ther November 1989 251:679-682
- Abstract
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- C F van Bezooijen and
- R M van Oorschot
The effect of age on antipyrine pharmacokinetics and metabolite formation in rats.
J Pharmacol Exp Ther November 1989 251:683-686
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- L X Cubeddu,
- T W Lovenberg,
- I S Hoffman,
- and R K Talmaciu
Phorbol esters and D2-dopamine receptors.
J Pharmacol Exp Ther November 1989 251:687-693
- Abstract
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- J L Reyes,
- E Meléndez,
- B A Escalante,
- and M C Namorado
Effect of synthesis inhibitors of thromboxane A2 and prostaglandin E2 on the regulation of sodium and water.
J Pharmacol Exp Ther November 1989 251:694-699
- Abstract
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- M Rudin and
- A Sauter
Dihydropyridine calcium antagonists reduce the consumption of high-energy phosphates in the rat brain. A study using combined 31P/1H magnetic resonance spectroscopy and 31P saturation transfer.
J Pharmacol Exp Ther November 1989 251:700-706
- Abstract
- Full Text (PDF)
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- N Inatomi,
- H Satoh,
- Y Maki,
- N Hashimoto,
- Z Itoh,
- and S Omura
An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs.
J Pharmacol Exp Ther November 1989 251:707-712
- Abstract
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- C Severi,
- D H Coy,
- R T Jensen,
- L Boschero,
- M C Anania,
- and G Delle Fave
Pharmacological characterization of [Leu-13-psi-CH2NH-Leu14]-bombesin as a specific bombesin receptor antagonist on isolated smooth muscle cells.
J Pharmacol Exp Ther November 1989 251:713-717
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- T Dennis,
- A Fournier,
- S St Pierre,
- and R Quirion
Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity.
J Pharmacol Exp Ther November 1989 251:718-725
- Abstract
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- G B Glavin
Activity of selective dopamine DA1 and DA2 agonists and antagonists on experimental gastric lesions and gastric acid secretion.
J Pharmacol Exp Ther November 1989 251:726-730
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- T Berg,
- E Schlichting,
- H Ishida,
- and O A Carretero
Kinin antagonist does not protect against the hypotensive response to endotoxin, anaphylaxis or acute pancreatitis.
J Pharmacol Exp Ther November 1989 251:731-734
- Abstract
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- J De Vry,
- I Donselaar,
- and J M Van Ree
Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol.
J Pharmacol Exp Ther November 1989 251:735-740
- Abstract
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- E J van Hoogdalem,
- C D Heijligers-Feijen,
- R A Mathôt,
- A T Wackwitz,
- J B van Bree,
- J C Verhoef,
- A G de Boer,
- and D D Breimer
Rectal absorption enhancement of cefoxitin and desglycinamide arginine vasopressin by sodium tauro-24,25-dihydrofusidate in conscious rats.
J Pharmacol Exp Ther November 1989 251:741-744
- Abstract
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- M Kato,
- H Maegawa,
- T Okano,
- K Inui,
- and R Hori
Effect of various chemical modifiers on H+ coupled transport of cephradine via dipeptide carriers in rabbit intestinal brush-border membranes: role of histidine residues.
J Pharmacol Exp Ther November 1989 251:745-749
- Abstract
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- P G Cox,
- W M Moons,
- F G Russel,
- and C A van Ginneken
Renal handling of salicyluric acid in the isolated perfused rat kidney: evidence for accumulation in tubular cells.
J Pharmacol Exp Ther November 1989 251:750-755
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- T Furukawa,
- Y Tsujimura,
- K Kitamura,
- H Tanaka,
- and Y Habuchi
Time- and voltage-dependent block of the delayed K+ current by quinidine in rabbit sinoatrial and atrioventricular nodes.
J Pharmacol Exp Ther November 1989 251:756-763
- Abstract
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- M Asano
Divergent pharmacological effects of three calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), chlorpromazine and calmidazolium, on isometric tension development and myosin light chain phosphorylation in intact bovine tracheal smooth muscle.
J Pharmacol Exp Ther November 1989 251:764-773
- Abstract
- Full Text (PDF)
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- L B Katz and
- D A Shriver
Rioprostil heals pre-existing aspirin-induced gastric lesions in dogs during daily aspirin administration without altering the anti-inflammatory or analgesic efficacy of aspirin.
J Pharmacol Exp Ther November 1989 251:774-781
- Abstract
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- S Estus and
- J L Blumer
Critical period of phenytoin teratogenic action in the sea urchin, Arbacia punctulata embryo.
J Pharmacol Exp Ther November 1989 251:782-789
- Abstract
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- G G Schnier,
- C L Laethem,
- and D R Koop
Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow.
J Pharmacol Exp Ther November 1989 251:790-796
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Agonist recognition site of the peripheral acetylcholine receptor ion channel complex differentiates the enantiomers of nicotine.

Effects of chronic morphine administration on the mu and delta opioid responses in the CA1 region of the rat hippocampus.

Antinociception after nicotine administration into the mesopontine tegmentum of rats: evidence for muscarinic actions.

D2/D1 ratio in the medial preoptic area affects copulation of male rats.

Neuroendocrine evidence for denervation supersensitivity of serotonin receptors: effects of the 5-HT agonist RU 24969 on corticotropin, corticosterone, prolactin and renin secretion.

Pharmacokinetics of naloxone: an insight into the locus of effect on stress-ulceration.

Inhibition of endopeptidase 24.15 slows the in vivo degradation of luteinizing hormone-releasing hormone.

Cysteine S-conjugates may act as kidney-selective prodrugs: formation of 6-mercaptopurine by the renal metabolism of S-(6-purinyl)-L-cysteine.

Reinforcing effect of alfentanil is mediated by mu opioid receptors: apparent pA2 analysis.

Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.

Pharmacological actions of a novel mixed opiate agonist/antagonist: naloxone benzoylhydrazone.

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

SK&F 104353: selective antagonism of peptidoleukotrine-induced changes in electrolyte transport by rat ileal mucosa in vitro.

Pharmacologic experiments on the interaction between crotoxin and the mammalian neuromuscular junction.

Opioid-induced prejunctional inhibition of vasoconstriction in the rabbit ear artery: alpha-2 adrenoceptor activation and external calcium.

Effects of Bay o 2752, a hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification.

Analogs of somatostatin selectively label distinct subtypes of somatostatin receptors in rat brain.

Glutamate receptors of the N-methyl-D-aspartate subtype in the myenteric plexus of the guinea pig ileum.

Serotonin depletion potentiates gastric secretory and motor responses to vagal but not peripheral gastric stimulants.

Antagonism to the actions of platelet activating factor by a nonpsychoactive cannabinoid.

A mu-specific opioid peptide agonist increases excitability of pyramidal neurons in untreated and receptor up-regulated hippocampus.

Aging does not alter brain muscarinic receptor-mediated phosphoinositide hydrolysis and its inhibition by phorbol esters, tetrodotoxin and receptor desensitization.

Role of adenosine in the gastric blood flow response to pentagastrin in the rat.

Characterization of an 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist.

Importance of central nervous system serotonin-1A receptors for mediating the hypotensive effect of urapidil.

Celiprolol does not protect against ventricular tachycardia or sudden death in the conscious canine: a comparison with pindolol in assessing the role of intrinsic sympathomimetic activity.

Angiotensin II receptor-mediated stimulation of cytosolic-free calcium and inositol phosphates in chick myocytes.

The anticholinergic activity of agents indicated for urinary incontinence is an important property for effective control of bladder dysfunction.

Indirect involvement of delta opioid receptors in cholecystokinin octapeptide-induced analgesia in mice.

Effects of nebivolol, atenolol and propranolol on in vivo cardiovascular and metabolic responses to isoproterenol in dogs.

Development and application of a radioimmunoassay for physostigmine.

Continuous physostigmine infusion in rats with excitotoxic lesions of the nucleus basalis magnocellularis: effects on performance in the water maze task and cortical cholinergic markers.

Neutrophils delay functional recovery of the post-hypoxic heart of the rabbit.

Effects of competitive and noncompetitive N-methyl-D-aspartate (NMDA) antagonists in rats trained to discriminate NMDA from saline.

Influence of protein kinase C activators on vascular tone and adrenergic neuroeffector events in the isolated rat kidney.

Alpha-2A and alpha-2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype.

Selective pressor enhancement by monoamine oxidase inhibitors in conscious rats.

Amiodarone blocks calcium current in single guinea pig ventricular myocytes.

Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart.

Dihydropyridine-sensitive and -insensitive components of acetylcholine release from rat motor nerve terminals.

Antiangiogenic action of heparin plus cortisone is associated with decreased collagenous protein synthesis in the chick chorioallantoic membrane system.

The effect of age on antipyrine pharmacokinetics and metabolite formation in rats.

Phorbol esters and D2-dopamine receptors.

Effect of synthesis inhibitors of thromboxane A2 and prostaglandin E2 on the regulation of sodium and water.

Dihydropyridine calcium antagonists reduce the consumption of high-energy phosphates in the rat brain. A study using combined 31P/1H magnetic resonance spectroscopy and 31P saturation transfer.

An erythromycin derivative, EM-523, induces motilin-like gastrointestinal motility in dogs.

Pharmacological characterization of [Leu-13-psi-CH2NH-Leu14]-bombesin as a specific bombesin receptor antagonist on isolated smooth muscle cells.

Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity.

Activity of selective dopamine DA1 and DA2 agonists and antagonists on experimental gastric lesions and gastric acid secretion.

Kinin antagonist does not protect against the hypotensive response to endotoxin, anaphylaxis or acute pancreatitis.

Food deprivation and acquisition of intravenous cocaine self-administration in rats: effect of naltrexone and haloperidol.

Rectal absorption enhancement of cefoxitin and desglycinamide arginine vasopressin by sodium tauro-24,25-dihydrofusidate in conscious rats.

Effect of various chemical modifiers on H+ coupled transport of cephradine via dipeptide carriers in rabbit intestinal brush-border membranes: role of histidine residues.

Renal handling of salicyluric acid in the isolated perfused rat kidney: evidence for accumulation in tubular cells.

Time- and voltage-dependent block of the delayed K+ current by quinidine in rabbit sinoatrial and atrioventricular nodes.

Divergent pharmacological effects of three calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), chlorpromazine and calmidazolium, on isometric tension development and myosin light chain phosphorylation in intact bovine tracheal smooth muscle.

Rioprostil heals pre-existing aspirin-induced gastric lesions in dogs during daily aspirin administration without altering the anti-inflammatory or analgesic efficacy of aspirin.

Critical period of phenytoin teratogenic action in the sea urchin, Arbacia punctulata embryo.

Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow.

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