Table of Contents

July 1989; 250 (1)

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- C W Stevens and
- T L Yaksh
Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.
J Pharmacol Exp Ther July 1989 250:1-8
- Abstract
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- E K Jackson
Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.
J Pharmacol Exp Ther July 1989 250:9-21
- Abstract
- Full Text (PDF)
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- S J Haleen,
- R P Steffen,
- I Sircar,
- T C Major,
- M D Taylor,
- T A Pugsley,
- and R E Weishaar
PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties.
J Pharmacol Exp Ther July 1989 250:22-30
- Abstract
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- R G Pendleton,
- G Gessner,
- and E Horner
Studies defining minimal receptor domains for angiotensin II.
J Pharmacol Exp Ther July 1989 250:31-36
- Abstract
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- D H Bobker and
- J T Williams
Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors.
J Pharmacol Exp Ther July 1989 250:37-43
- Abstract
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- R J Heaslip and
- B D Sickels
Evidence that prostaglandins can contract the rat aorta via a novel protein kinase C-dependent mechanism.
J Pharmacol Exp Ther July 1989 250:44-51
- Abstract
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- G J Marek,
- A A Li,
- and L S Seiden
Selective 5-hydroxytryptamine2 antagonists have antidepressant-like effects on differential-reinforcement-of-low-rate 72-second schedule.
J Pharmacol Exp Ther July 1989 250:52-59
- Abstract
- Full Text (PDF)
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- G J Marek,
- A A Li,
- and L S Seiden
Evidence for involvement of 5-hydroxytryptamine1 receptors in antidepressant-like drug effects on differential-reinforcement-of-low-rate 72-second behavior.
J Pharmacol Exp Ther July 1989 250:60-71
- Abstract
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- G Bagdy,
- K Szemeredi,
- B Kanyicska,
- and D L Murphy
Different serotonin receptors mediate blood pressure, heart rate, plasma catecholamine and prolactin responses to m-chlorophenylpiperazine in conscious rats.
J Pharmacol Exp Ther July 1989 250:72-78
- Abstract
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- S Barone,
- P C Churchill,
- and K A Jacobson
Adenosine receptor prodrugs: towards kidney-selective dialkylxanthines.
J Pharmacol Exp Ther July 1989 250:79-85
- Abstract
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- J Zawilska and
- P M Iuvone
Catecholamine receptors regulating serotonin N-acetyltransferase activity and melatonin content of chicken retina and pineal gland: D2-dopamine receptors in retina and alpha-2 adrenergic receptors in pineal gland.
J Pharmacol Exp Ther July 1989 250:86-92
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- R E Howell,
- P N Lanken,
- J H Hansen-Flaschen,
- F R Haselton,
- S M Albelda,
- and A P Fishman
Pulmonary extraction of propranolol in normal and oxygen-toxic sheep.
J Pharmacol Exp Ther July 1989 250:93-99
- Abstract
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- J W Ferkany,
- D J Kyle,
- J Willets,
- W J Rzeszotarski,
- M E Guzewska,
- S R Ellenberger,
- S M Jones,
- A I Sacaan,
- L D Snell,
- and S Borosky
Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.
J Pharmacol Exp Ther July 1989 250:100-109
- Abstract
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- B S Schonwetter,
- R R Luedtke,
- M P Kung,
- J Billings,
- H F Kung,
- and P B Molinoff
Characterization of membrane-bound and soluble D2 receptors in canine caudate using [125I]IBZM.
J Pharmacol Exp Ther July 1989 250:110-116
- Abstract
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- D M Niedzwiecki,
- L X Cubeddu,
- and R B Mailman
Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.
J Pharmacol Exp Ther July 1989 250:117-125
- Abstract
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- D M Niedzwiecki,
- L X Cubeddu,
- and R B Mailman
Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.
J Pharmacol Exp Ther July 1989 250:126-133
- Abstract
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- D J Greenblatt,
- B L Ehrenberg,
- J Gunderman,
- J M Scavone,
- N T Tai,
- J S Harmatz,
- and R I Shader
Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam.
J Pharmacol Exp Ther July 1989 250:134-140
- Abstract
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- J C Chen,
- P B Crino,
- P W Schnepper,
- A C To,
- and L Volicer
Increased serotonin efflux by a partially oxidized serotonin: tryptamine-4,5-dione.
J Pharmacol Exp Ther July 1989 250:141-148
- Abstract
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- L S Ramsammy,
- C Josepovitz,
- B P Lane,
- and G J Kaloyanides
Polyaspartic acid protects against gentamicin nephrotoxicity in the rat.
J Pharmacol Exp Ther July 1989 250:149-153
- Abstract
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- T D Bjornsson,
- D E Schneider,
- and H Berger, Jr
Aspirin acetylates fibrinogen and enhances fibrinolysis. Fibrinolytic effect is independent of changes in plasminogen activator levels.
J Pharmacol Exp Ther July 1989 250:154-161
- Abstract
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- B M Baron,
- M W Dudley,
- D R McCarty,
- F P Miller,
- I J Reynolds,
- and C J Schmidt
Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.
J Pharmacol Exp Ther July 1989 250:162-169
- Abstract
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- C F Neely,
- P J Kadowitz,
- H Lippton,
- M Neiman,
- and A L Hyman
Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed.
J Pharmacol Exp Ther July 1989 250:170-176
- Abstract
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- Y Ohno and
- J E Warnick
Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro.
J Pharmacol Exp Ther July 1989 250:177-183
- Abstract
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- K L Preston,
- G E Bigelow,
- W K Bickel,
- and I A Liebson
Drug discrimination in human postaddicts: agonist-antagonist opioids.
J Pharmacol Exp Ther July 1989 250:184-196
- Abstract
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- C P France,
- A M Snyder,
- and J H Woods
Analgesic effects of phencyclidine-like drugs in rhesus monkeys.
J Pharmacol Exp Ther July 1989 250:197-201
- Abstract
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- M D Dulaney, Jr,
- R W Rockhold,
- A C Porter,
- B Hoskins,
- and I K Ho
Changes in drinking activity, urine volume and urinary electrolyte excretion after intracerebroventricular administration of diisopropylfluorophosphate.
J Pharmacol Exp Ther July 1989 250:202-209
- Abstract
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- A K Cho,
- M Hiramatsu,
- R N Pechnick,
- and E Di Stefano
Pharmacokinetic and pharmacodynamic evaluation of phencyclidine and its decadeutero variant.
J Pharmacol Exp Ther July 1989 250:210-215
- Abstract
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- J F Tomera and
- J Martyn
Intraperitoneal endotoxin but not protein malnutrition shifts d-tubocurarine dose-response curves in mouse gastrocnemius muscle.
J Pharmacol Exp Ther July 1989 250:216-220
- Abstract
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- J C Deutsch and
- J F Kolhouse
Structural specificity of mechanisms controlling the hepatic uptake and biliary output of methotrexate in the rat.
J Pharmacol Exp Ther July 1989 250:221-226
- Abstract
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- M M Foreman,
- R W Fuller,
- M D Hynes,
- J S Gidda,
- C L Nichols,
- J M Schaus,
- E C Kornfeld,
- and J A Clemens
Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist.
J Pharmacol Exp Ther July 1989 250:227-235
- Abstract
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- E M Kudlacz,
- H A Navarro,
- and T A Slotkin
Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation.
J Pharmacol Exp Ther July 1989 250:236-240
- Abstract
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- K W Locke,
- B Gorney,
- M Cornfeldt,
- and S Fielding
Characterization of the discriminative stimulus effects of physostigmine in the rat.
J Pharmacol Exp Ther July 1989 250:241-246
- Abstract
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- A M Torres,
- J V Rodriguez,
- and M M Elías
Vulnerability of the thick ascending limb to glutathione depletion in rat kidney: effects of diuretics and indomethacin.
J Pharmacol Exp Ther July 1989 250:247-253
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- T Tadano,
- S Satoh,
- N Satoh,
- K Kisara,
- Y Arai,
- S K Kim,
- and H Kinemuchi
Potentiation of para-hydroxyamphetamine-induced head-twitch response by inhibition of monoamine oxidase type A in the brain.
J Pharmacol Exp Ther July 1989 250:254-260
- Abstract
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- U Quast and
- N S Cook
In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide.
J Pharmacol Exp Ther July 1989 250:261-271
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- Y Kitada,
- M Kobayashi,
- A Narimatsu,
- and Y Ohizumi
Potent stimulation of myofilament force and adenosine triphosphatase activity of canine cardiac muscle through a direct enhancement of troponin C Ca++ binding by MCI-154, a novel cardiotonic agent.
J Pharmacol Exp Ther July 1989 250:272-277
- Abstract
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- M Hiraoka and
- Z Fan
Activation of ATP-sensitive outward K+ current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes.
J Pharmacol Exp Ther July 1989 250:278-285
- Abstract
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- E Okabe,
- M Sugihara,
- K Tanaka,
- H Sasaki,
- and H Ito
Calmodulin and free oxygen radicals interaction with steady-state calcium accumulation and passive calcium permeability of cardiac sarcoplasmic reticulum.
J Pharmacol Exp Ther July 1989 250:286-292
- Abstract
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- O Marquis,
- C Robaut,
- and I Cavero
Evidence for the existence and ionic modulation of platelet-activating factor receptors mediating degranulatory responses in human polymorphonuclear leukocytes.
J Pharmacol Exp Ther July 1989 250:293-300
- Abstract
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- B Zimmerli,
- J Valantinas,
- and P J Meier
Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles.
J Pharmacol Exp Ther July 1989 250:301-308
- Abstract
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- J P Gies,
- C Bertrand,
- P Vanderheyden,
- F Waeldele,
- P Dumont,
- G Pauli,
- and Y Landry
Characterization of muscarinic receptors in human, guinea pig and rat lung.
J Pharmacol Exp Ther July 1989 250:309-315
- Abstract
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- B M Bennett,
- D C Leitman,
- H Schröder,
- J H Kawamoto,
- K Nakatsu,
- and F Murad
Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines.
J Pharmacol Exp Ther July 1989 250:316-323
- Abstract
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- T Nohjoh,
- H Suzuki,
- Y Sawada,
- Y Sugiyama,
- T Iga,
- and M Hanano
Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus.
J Pharmacol Exp Ther July 1989 250:324-328
- Abstract
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- M Mousli,
- C Bronner,
- J L Bueb,
- E Tschirhart,
- J P Gies,
- and Y Landry
Activation of rat peritoneal mast cells by substance P and mastoparan.
J Pharmacol Exp Ther July 1989 250:329-335
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- M Wong and
- P G Wells
Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).
J Pharmacol Exp Ther July 1989 250:336-342
- Abstract
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- Y Y Zeng,
- C G Benishin,
- and P K Pang
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.
J Pharmacol Exp Ther July 1989 250:343-351
- Abstract
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- Y Y Zeng,
- C G Benishin,
- and P K Pang
Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. II. Studies with guanosine 5'-(gamma)triphosphate.
J Pharmacol Exp Ther July 1989 250:352-357
- Abstract
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- X M Yang,
- Z P Luo,
- and J H Zhou
Behavioral evidence for the role of noradrenaline in the putative anxiogenic actions of the inverse benzodiazepine receptor agonist methyl-4-ethyl-6,7-dimethoxy-beta-carboline-3-carboxylate.
J Pharmacol Exp Ther July 1989 250:358-363
- Abstract
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- U Ravens,
- X L Wang,
- and E Wettwer
Alpha adrenoceptor stimulation reduces outward currents in rat ventricular myocytes.
J Pharmacol Exp Ther July 1989 250:364-370
- Abstract
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- F J Ayesta and
- J Flórez
Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance.
J Pharmacol Exp Ther July 1989 250:371-378
- Abstract
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- M Frenken
Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.
J Pharmacol Exp Ther July 1989 250:379-387
- Abstract
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- H Ishihara,
- H Ozaki,
- K Sato,
- M Hori,
- H Karaki,
- S Watabe,
- Y Kato,
- N Fusetani,
- K Hashimoto,
- and D Uemura
Calcium-independent activation of contractile apparatus in smooth muscle by calyculin-A.
J Pharmacol Exp Ther July 1989 250:388-396
- Abstract
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- A Zaza,
- G Malfatto,
- and M R Rosen
Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart.
J Pharmacol Exp Ther July 1989 250:397-405
- Abstract
- Full Text (PDF)
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- M W Kalichman,
- H C Powell,
- and R R Myers
Quantitative histologic analysis of local anesthetic-induced injury to rat sciatic nerve.
J Pharmacol Exp Ther July 1989 250:406-413
- Abstract
- Full Text (PDF)
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- K Beaumont,
- D A Vaughn,
- and D P Healy
Thiazide diuretic receptors: autoradiographic localization in rat kidney with [3H]metolazone.
J Pharmacol Exp Ther July 1989 250:414-419
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.

Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.

PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties.

Studies defining minimal receptor domains for angiotensin II.

Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors.

Evidence that prostaglandins can contract the rat aorta via a novel protein kinase C-dependent mechanism.

Selective 5-hydroxytryptamine2 antagonists have antidepressant-like effects on differential-reinforcement-of-low-rate 72-second schedule.

Evidence for involvement of 5-hydroxytryptamine1 receptors in antidepressant-like drug effects on differential-reinforcement-of-low-rate 72-second behavior.

Different serotonin receptors mediate blood pressure, heart rate, plasma catecholamine and prolactin responses to m-chlorophenylpiperazine in conscious rats.

Adenosine receptor prodrugs: towards kidney-selective dialkylxanthines.

Catecholamine receptors regulating serotonin N-acetyltransferase activity and melatonin content of chicken retina and pineal gland: D2-dopamine receptors in retina and alpha-2 adrenergic receptors in pineal gland.

Pulmonary extraction of propranolol in normal and oxygen-toxic sheep.

Pharmacological profile of NPC 12626, a novel, competitive N-methyl-D-aspartate receptor antagonist.

Characterization of membrane-bound and soluble D2 receptors in canine caudate using [125I]IBZM.

Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum.

Comparative anticholinergic properties of thioridazine, mesoridazine and sulforidazine.

Kinetic and dynamic study of intravenous lorazepam: comparison with intravenous diazepam.

Increased serotonin efflux by a partially oxidized serotonin: tryptamine-4,5-dione.

Polyaspartic acid protects against gentamicin nephrotoxicity in the rat.

Aspirin acetylates fibrinogen and enhances fibrinolysis. Fibrinolytic effect is independent of changes in plasminogen activator levels.

Guanine nucleotides are competitive inhibitors of N-methyl-D-aspartate at its receptor site both in vitro and in vivo.

Adenosine does not mediate the pulmonary vasodilator response of adenosine 5'-triphosphate in the feline pulmonary vascular bed.

Presynaptic activation of the spinal serotonergic system in the rat by phencyclidine in vitro.

Drug discrimination in human postaddicts: agonist-antagonist opioids.

Analgesic effects of phencyclidine-like drugs in rhesus monkeys.

Changes in drinking activity, urine volume and urinary electrolyte excretion after intracerebroventricular administration of diisopropylfluorophosphate.

Pharmacokinetic and pharmacodynamic evaluation of phencyclidine and its decadeutero variant.

Intraperitoneal endotoxin but not protein malnutrition shifts d-tubocurarine dose-response curves in mouse gastrocnemius muscle.

Structural specificity of mechanisms controlling the hepatic uptake and biliary output of methotrexate in the rat.

Preclinical studies on quinelorane, a potent and highly selective D2-dopaminergic agonist.

Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation.

Characterization of the discriminative stimulus effects of physostigmine in the rat.

Vulnerability of the thick ascending limb to glutathione depletion in rat kidney: effects of diuretics and indomethacin.

Potentiation of para-hydroxyamphetamine-induced head-twitch response by inhibition of monoamine oxidase type A in the brain.

In vitro and in vivo comparison of two K+ channel openers, diazoxide and cromakalim, and their inhibition by glibenclamide.

Potent stimulation of myofilament force and adenosine triphosphatase activity of canine cardiac muscle through a direct enhancement of troponin C Ca++ binding by MCI-154, a novel cardiotonic agent.

Activation of ATP-sensitive outward K+ current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes.

Calmodulin and free oxygen radicals interaction with steady-state calcium accumulation and passive calcium permeability of cardiac sarcoplasmic reticulum.

Evidence for the existence and ionic modulation of platelet-activating factor receptors mediating degranulatory responses in human polymorphonuclear leukocytes.

Multispecificity of Na+-dependent taurocholate uptake in basolateral (sinusoidal) rat liver plasma membrane vesicles.

Characterization of muscarinic receptors in human, guinea pig and rat lung.

Relationship between biotransformation of glyceryl trinitrate and cyclic GMP accumulation in various cultured cell lines.

Transport of cefodizime, a novel third generation cephalosporin antibiotic, in isolated rat choroid plexus.

Activation of rat peritoneal mast cells by substance P and mastoparan.

Modulation of embryonic glutathione reductase and phenytoin teratogenicity by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU).

Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. I. Studies with fluoride.

Guanine nucleotide binding proteins may modulate gating of calcium channels in vascular smooth muscle. II. Studies with guanosine 5'-(gamma)triphosphate.

Behavioral evidence for the role of noradrenaline in the putative anxiogenic actions of the inverse benzodiazepine receptor agonist methyl-4-ethyl-6,7-dimethoxy-beta-carboline-3-carboxylate.

Alpha adrenoceptor stimulation reduces outward currents in rat ventricular myocytes.

Tolerance to respiratory actions of sufentanil: functional tolerance and route-dependent differential tolerance.

Evidence for two populations of 5-hydroxytryptamine receptors in dog basilar artery.

Calcium-independent activation of contractile apparatus in smooth muscle by calyculin-A.

Electrophysiologic effects of ketanserin on canine Purkinje fibers, ventricular myocardium and the intact heart.

Quantitative histologic analysis of local anesthetic-induced injury to rat sciatic nerve.

Thiazide diuretic receptors: autoradiographic localization in rat kidney with [3H]metolazone.

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