Table of Contents

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- J M Goldstein,
- L C Litwin,
- E B Sutton,
- and J B Malick
Effects of ICI 169,369, a selective serotonin2 antagonist, in electrophysiological tests predictive of antipsychotic activity.
J Pharmacol Exp Ther June 1989 249:673-680
- Abstract
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- A J Bean,
- T E Adrian,
- I M Modlin,
- and R H Roth
Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations.
J Pharmacol Exp Ther June 1989 249:681-687
- Abstract
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- F Lux,
- Y H Han,
- D A Brase,
- and W L Dewey
Studies on the mechanism of hypoglycemia induced by intrathecal morphine: dissociation from behavioral effects, effects of tolerance and depletion of liver glycogen.
J Pharmacol Exp Ther June 1989 249:688-693
- Abstract
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- F A Gesek,
- E J Cragoe, Jr,
- and J W Strandhoy
Synergistic alpha-1 and alpha-2 adrenergic stimulation of rat proximal nephron Na+/H+ exchange.
J Pharmacol Exp Ther June 1989 249:694-700
- Abstract
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- R Weizman,
- A Weizman,
- K A Kook,
- F Vocci,
- S I Deutsch,
- and S M Paul
Repeated swim stress alters brain benzodiazepine receptors measured in vivo.
J Pharmacol Exp Ther June 1989 249:701-707
- Abstract
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- M A Rogawski,
- A Thurkauf,
- S Yamaguchi,
- K C Rice,
- A E Jacobson,
- and M V Mattson
Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline.
J Pharmacol Exp Ther June 1989 249:708-712
- Abstract
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- T R Insel,
- G Battaglia,
- J N Johannessen,
- S Marra,
- and E B De Souza
3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys.
J Pharmacol Exp Ther June 1989 249:713-720
- Abstract
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- D D Mott,
- A C Bragdon,
- D V Lewis,
- and W A Wilson
Baclofen has a proepileptic effect in the rat dentate gyrus.
J Pharmacol Exp Ther June 1989 249:721-725
- Abstract
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- J Loscalzo,
- D Smick,
- N Andon,
- and J Cooke
S-nitrosocaptopril. I. Molecular characterization and effects on the vasculature and on platelets.
J Pharmacol Exp Ther June 1989 249:726-729
- Abstract
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- J P Cooke,
- N Andon,
- and J Loscalzo
S-nitrosocaptopril. II. Effects on vascular reactivity.
J Pharmacol Exp Ther June 1989 249:730-734
- Abstract
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- W D Atchison
Alterations of spontaneous and evoked release of acetylcholine during dithiobiuret-induced neuromuscular weakness.
J Pharmacol Exp Ther June 1989 249:735-743
- Abstract
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- N J Riachi,
- J C LaManna,
- and S I Harik
Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain.
J Pharmacol Exp Ther June 1989 249:744-748
- Abstract
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- R L Balster
Substitution and antagonism in rats trained to discriminate (+)-N-allylnormetazocine from saline.
J Pharmacol Exp Ther June 1989 249:749-756
- Abstract
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- K A Kirchner
Role of medullary plasma flow in the attenuated furosemide response in indomethacin-treated rats.
J Pharmacol Exp Ther June 1989 249:757-761
- Abstract
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- S C Roerig and
- J M Fujimoto
Multiplicative interaction between intrathecally and intracerebroventricularly administered mu opioid agonists but limited interactions between delta and kappa agonists for antinociception in mice.
J Pharmacol Exp Ther June 1989 249:762-768
- Abstract
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- V L Coffin,
- M B Latranyi,
- and R E Chipkin
Acute extrapyramidal syndrome in Cebus monkeys: development mediated by dopamine D2 but not D1 receptors.
J Pharmacol Exp Ther June 1989 249:769-774
- Abstract
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- B T Liang
Characterization of the adenosine receptor in cultured embryonic chick atrial myocytes: coupling to modulation of contractility and adenylate cyclase activity and identification by direct radioligand binding.
J Pharmacol Exp Ther June 1989 249:775-784
- Abstract
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- S Kalsner and
- M Quillan
Cholinergic contraction to field stimulation in coronary arteries of cattle.
J Pharmacol Exp Ther June 1989 249:785-789
- Abstract
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- A S Freeman,
- M D Kelland,
- C Rouillard,
- and L A Chiodo
Electrophysiological characteristics and pharmacological responsiveness of midbrain dopaminergic neurons of the aged rat.
J Pharmacol Exp Ther June 1989 249:790-797
- Abstract
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- S J Kelly,
- A C Black, Jr,
- and J R West
Changes in the muscarinic cholinergic receptors in the hippocampus of rats exposed to ethyl alcohol during the brain growth spurt.
J Pharmacol Exp Ther June 1989 249:798-804
- Abstract
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- E F Smith, 3rd,
- M J Slivjak,
- R D Eckardt,
- and J F Newton
Antagonism of leukotriene C4, leukotriene D4 and leukotriene E4 vasoconstrictor responses in the conscious rat with the peptidoleukotriene receptor antagonist SK&F 104353: evidence for leukotriene D4 receptor heterogeneity.
J Pharmacol Exp Ther June 1989 249:805-811
- Abstract
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- T A Deisher,
- S Mankani,
- and B B Hoffman
Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.
J Pharmacol Exp Ther June 1989 249:812-819
- Abstract
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- S K Youngster,
- P K Sonsalla,
- B A Sieber,
- and R E Heikkila
Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.
J Pharmacol Exp Ther June 1989 249:820-828
- Abstract
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- S K Youngster,
- W J Nicklas,
- and R E Heikkila
Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs.
J Pharmacol Exp Ther June 1989 249:829-835
- Abstract
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- K Yamada,
- M D Saltarelli,
- and J T Coyle
Specificity of the activation of [3H]hemicholinium-3 binding by phospholipase A2.
J Pharmacol Exp Ther June 1989 249:836-842
- Abstract
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- L Noronha-Blob,
- V Lowe,
- A Patton,
- B Canning,
- D Costello,
- and W J Kinnier
Muscarinic receptors: relationships among phosphoinositide breakdown, adenylate cyclase inhibition, in vitro detrusor muscle contractions and in vivo cystometrogram studies in guinea pig bladder.
J Pharmacol Exp Ther June 1989 249:843-851
- Abstract
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- S Sabatini,
- J C Wharton,
- H K Lim,
- and N A Kurtzman
Dimethyl sulfoxide affects water flow through a nonosmolar action.
J Pharmacol Exp Ther June 1989 249:852-857
- Abstract
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- G M Rubanyi,
- D Desiderio,
- A Luisi,
- A Johns,
- and E J Sybertz
Phorbol dibutyrate inhibits release and action of endothelium-derived relaxing factor(s) in canine blood vessels.
J Pharmacol Exp Ther June 1989 249:858-863
- Abstract
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- M H Heijna,
- F Hogenboom,
- P S Portoghese,
- A H Mulder,
- and A N Schoffelmeer
Mu- and delta-opioid receptor-mediated inhibition of adenylate cyclase activity stimulated by released endogenous dopamine in rat neostriatal slices; demonstration of potent delta-agonist activity of bremazocine.
J Pharmacol Exp Ther June 1989 249:864-868
- Abstract
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- I Braakman,
- G M Groothuis,
- and D K Meijer
Zonal compartmentation of perfused rat liver: plasma reappearance of rhodamine B explained.
J Pharmacol Exp Ther June 1989 249:869-873
- Abstract
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- M Polhuijs,
- F Kuipers,
- R J Vonk,
- and G J Mulder
Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.
J Pharmacol Exp Ther June 1989 249:874-878
- Abstract
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- E Hamel,
- J P Robert,
- A R Young,
- and E T MacKenzie
Pharmacological properties of the receptor(s) involved in the 5-hydroxytryptamine-induced contraction of the feline middle cerebral artery.
J Pharmacol Exp Ther June 1989 249:879-889
- Abstract
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- K Kamata,
- N Miyata,
- and Y Kasuya
Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats.
J Pharmacol Exp Ther June 1989 249:890-894
- Abstract
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- A Abe and
- H Karaki
Effect of forskolin on cytosolic Ca++ level and contraction in vascular smooth muscle.
J Pharmacol Exp Ther June 1989 249:895-900
- Abstract
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- J B van Bree,
- A G de Boer,
- J C Verhoef,
- M Danhof,
- and D D Breimer
Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells.
J Pharmacol Exp Ther June 1989 249:901-905
- Abstract
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- N F Schor
Neocarzinostatin induces neuronal morphology of mouse neuroblastoma in culture.
J Pharmacol Exp Ther June 1989 249:906-910
- Abstract
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- R M Booze,
- E A Crisostomo,
- and J N Davis
Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.
J Pharmacol Exp Ther June 1989 249:911-920
- Abstract
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- W A Khan,
- S S Park,
- H V Gelboin,
- D R Bickers,
- and H Mukhtar
Epidermal cytochrome P-450: immunochemical characterization of isoform induced by topical application of 3-methylcholanthrene to neonatal rat.
J Pharmacol Exp Ther June 1989 249:921-927
- Abstract
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- N M Appel,
- J F Contrera,
- and E B De Souza
Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies.
J Pharmacol Exp Ther June 1989 249:928-943
- Abstract
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- P F Smith,
- G D Hoke,
- D W Alberts,
- P J Bugelski,
- S Lupo,
- C K Mirabelli,
- and G F Rush
Mechanism of toxicity of an experimental bidentate phosphine gold complexed antineoplastic agent in isolated rat hepatocytes.
J Pharmacol Exp Ther June 1989 249:944-950
- Abstract
- Full Text (PDF)

Effects of ICI 169,369, a selective serotonin2 antagonist, in electrophysiological tests predictive of antipsychotic activity.

Dopamine and neurotensin storage in colocalized and noncolocalized neuronal populations.

Studies on the mechanism of hypoglycemia induced by intrathecal morphine: dissociation from behavioral effects, effects of tolerance and depletion of liver glycogen.

Synergistic alpha-1 and alpha-2 adrenergic stimulation of rat proximal nephron Na+/H+ exchange.

Repeated swim stress alters brain benzodiazepine receptors measured in vivo.

Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline.

3,4-Methylenedioxymethamphetamine ("ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys.

Baclofen has a proepileptic effect in the rat dentate gyrus.

S-nitrosocaptopril. I. Molecular characterization and effects on the vasculature and on platelets.

S-nitrosocaptopril. II. Effects on vascular reactivity.

Alterations of spontaneous and evoked release of acetylcholine during dithiobiuret-induced neuromuscular weakness.

Entry of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine into the rat brain.

Substitution and antagonism in rats trained to discriminate (+)-N-allylnormetazocine from saline.

Role of medullary plasma flow in the attenuated furosemide response in indomethacin-treated rats.

Multiplicative interaction between intrathecally and intracerebroventricularly administered mu opioid agonists but limited interactions between delta and kappa agonists for antinociception in mice.

Acute extrapyramidal syndrome in Cebus monkeys: development mediated by dopamine D2 but not D1 receptors.

Characterization of the adenosine receptor in cultured embryonic chick atrial myocytes: coupling to modulation of contractility and adenylate cyclase activity and identification by direct radioligand binding.

Cholinergic contraction to field stimulation in coronary arteries of cattle.

Electrophysiological characteristics and pharmacological responsiveness of midbrain dopaminergic neurons of the aged rat.

Changes in the muscarinic cholinergic receptors in the hippocampus of rats exposed to ethyl alcohol during the brain growth spurt.

Antagonism of leukotriene C4, leukotriene D4 and leukotriene E4 vasoconstrictor responses in the conscious rat with the peptidoleukotriene receptor antagonist SK&F 104353: evidence for leukotriene D4 receptor heterogeneity.

Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.

Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.

Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs.

Specificity of the activation of [3H]hemicholinium-3 binding by phospholipase A2.

Muscarinic receptors: relationships among phosphoinositide breakdown, adenylate cyclase inhibition, in vitro detrusor muscle contractions and in vivo cystometrogram studies in guinea pig bladder.

Dimethyl sulfoxide affects water flow through a nonosmolar action.

Phorbol dibutyrate inhibits release and action of endothelium-derived relaxing factor(s) in canine blood vessels.

Mu- and delta-opioid receptor-mediated inhibition of adenylate cyclase activity stimulated by released endogenous dopamine in rat neostriatal slices; demonstration of potent delta-agonist activity of bremazocine.

Zonal compartmentation of perfused rat liver: plasma reappearance of rhodamine B explained.

Stereoselectivity of glutathione conjugation: blood elimination of alpha-bromoisovalerylurea enantiomers and biliary excretion of the conjugates in unanesthetized normal or congenitally jaundiced rats.

Pharmacological properties of the receptor(s) involved in the 5-hydroxytryptamine-induced contraction of the feline middle cerebral artery.

Involvement of endothelial cells in relaxation and contraction responses of the aorta to isoproterenol in naive and streptozotocin-induced diabetic rats.

Effect of forskolin on cytosolic Ca++ level and contraction in vascular smooth muscle.

Transport of vasopressin fragments across the blood-brain barrier: in vitro studies using monolayer cultures of bovine brain endothelial cells.

Neocarzinostatin induces neuronal morphology of mouse neuroblastoma in culture.

Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.

Epidermal cytochrome P-450: immunochemical characterization of isoform induced by topical application of 3-methylcholanthrene to neonatal rat.

Fenfluramine selectively and differentially decreases the density of serotonergic nerve terminals in rat brain: evidence from immunocytochemical studies.

Mechanism of toxicity of an experimental bidentate phosphine gold complexed antineoplastic agent in isolated rat hepatocytes.

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