Table of Contents

July 1987; 242 (1)

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- J E Shook,
- J T Pelton,
- P K Lemcke,
- F Porreca,
- V J Hruby,
- and T F Burks
Mu opioid antagonist properties of a cyclic somatostatin octapeptide in vivo: identification of mu receptor-related functions.
J Pharmacol Exp Ther July 1987 242:1-7
- Abstract
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- H Bitterman,
- G R Phillips, 3rd,
- G Dragon,
- and A M Lefer
Potentiation of the protective effects of a converting enzyme inhibitor and a thromboxane synthetase inhibitor in hemorrhagic shock.
J Pharmacol Exp Ther July 1987 242:8-14
- Abstract
- Full Text (PDF)
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- R A Cruciani,
- R A Lutz,
- P J Munson,
- and D Rodbard
Naloxonazine effects on the interaction of enkephalin analogs with mu-1, mu and delta opioid binding sites in rat brain membranes.
J Pharmacol Exp Ther July 1987 242:15-20
- Abstract
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- J A Van Loon and
- R M Weinshilboum
Human lymphocyte thiopurine methyltransferase pharmacogenetics: effect of phenotype on 6-mercaptopurine-induced inhibition of mitogen stimulation.
J Pharmacol Exp Ther July 1987 242:21-26
- Abstract
- Full Text (PDF)
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- Z Gregus,
- A F Stein,
- and C D Klaassen
Effect of inhibition of gamma-glutamyltranspeptidase on biliary and urinary excretion of glutathione-derived thiols and methylmercury.
J Pharmacol Exp Ther July 1987 242:27-32
- Abstract
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- J D Leander,
- J C Hart,
- and R L Zerbe
Kappa agonist-induced diuresis: evidence for stereoselectivity, strain differences, independence of hydration variables and a result of decreased plasma vasopressin levels.
J Pharmacol Exp Ther July 1987 242:33-39
- Abstract
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- J V Barnett,
- D S Segal,
- and R Kuczenski
Repeated amphetamine pretreatment alters the responsiveness of striatal dopamine-stimulated adenylate cyclase to amphetamine-induced desensitization.
J Pharmacol Exp Ther July 1987 242:40-47
- Abstract
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- P P De Deyn and
- R L Macdonald
CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture.
J Pharmacol Exp Ther July 1987 242:48-55
- Abstract
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- T E Nelson
Ryanodine: antithetical calcium channel effects in skeletal muscle sarcoplasmic reticulum.
J Pharmacol Exp Ther July 1987 242:56-61
- Abstract
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- R A Hahn and
- B R MacDonald
Primate myocardial and systemic hemodynamic responses to leukotriene D4: antagonism by LY171883.
J Pharmacol Exp Ther July 1987 242:62-69
- Abstract
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- S J Moore,
- J C Norris,
- D A Walsh,
- and A S Hume
Antidotal use of methemoglobin forming cyanide antagonists in concurrent carbon monoxide/cyanide intoxication.
J Pharmacol Exp Ther July 1987 242:70-73
- Abstract
- Full Text (PDF)
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- R P Shank,
- J F Gardocki,
- C R Schneider,
- J L Vaught,
- P E Setler,
- B E Maryanoff,
- and D F McComsey
Preclinical evaluation of McN-5707 as a potential antidepressant.
J Pharmacol Exp Ther July 1987 242:74-84
- Abstract
- Full Text (PDF)
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- B P Fine,
- A Ty,
- N Lestrange,
- E Maher,
- and O R Levine
Diuretic-induced growth failure in rats and its reversal by sodium repletion.
J Pharmacol Exp Ther July 1987 242:85-89
- Abstract
- Full Text (PDF)
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- S Wigdor and
- G L Wilcox
Central and systemic morphine-induced antinociception in mice: contribution of descending serotonergic and noradrenergic pathways.
J Pharmacol Exp Ther July 1987 242:90-95
- Abstract
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- S M Owens,
- W C Hardwick,
- and D Blackall
Phencyclidine pharmacokinetic scaling among species.
J Pharmacol Exp Ther July 1987 242:96-101
- Abstract
- Full Text (PDF)
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- J Joselevitz-Goldman,
- M E Upsher,
- and H R Weiss
Effects of propranolol on regional O2 supply and O2 consumption in reperfused dog myocardium.
J Pharmacol Exp Ther July 1987 242:102-107
- Abstract
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- B M Clancy,
- R Osman,
- and S Maayani
Kinetics of competitive drug action at 5-hydroxytryptamine2 receptors in isolated rabbit aorta.
J Pharmacol Exp Ther July 1987 242:108-114
- Abstract
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- C A Altar,
- W C Boyar,
- E Oei,
- and P L Wood
Dopamine autoreceptors modulate the in vivo release of dopamine in the frontal, cingulate and entorhinal cortices.
J Pharmacol Exp Ther July 1987 242:115-120
- Abstract
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- P J Rice,
- A Hamada,
- D D Miller,
- and P N Patil
Asymmetric catecholimidazolines and catecholamidines: affinity and efficacy relationships at the alpha adrenoreceptor in rat aorta.
J Pharmacol Exp Ther July 1987 242:121-130
- Abstract
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- C J Helke,
- E T Phillips,
- and J T O'Neill
Intrathecal administration of a substance P receptor antagonist: studies on peripheral and central nervous system hemodynamics and on specificity of action.
J Pharmacol Exp Ther July 1987 242:131-136
- Abstract
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- E D Hall,
- J M McCall,
- R L Chase,
- P A Yonkers,
- and J M Braughler
A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage.
J Pharmacol Exp Ther July 1987 242:137-142
- Abstract
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- S Nagahama,
- H S Ann,
- Y F Chen,
- M D Lindheimer,
- and S Oparil
Role of vasopressin in the cardiovascular effects of LY171555, a selective dopamine D2 receptor agonist: studies in conscious Brattleboro and Long-Evans rats.
J Pharmacol Exp Ther July 1987 242:143-151
- Abstract
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- P P Sokol,
- P D Holohan,
- and C R Ross
The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles.
J Pharmacol Exp Ther July 1987 242:152-157
- Abstract
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- R J Shebuski,
- E H Ohlstein,
- J M Smith, Jr,
- and R R Ruffolo, Jr
Enhanced pulmonary alpha-2 adrenoceptor responsiveness under conditions of elevated pulmonary vascular tone.
J Pharmacol Exp Ther July 1987 242:158-165
- Abstract
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- S Wanwimolruk and
- G Levy
Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition.
J Pharmacol Exp Ther July 1987 242:166-172
- Abstract
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- S H Zorn,
- R S Duman,
- A Giachetti,
- R Micheletti,
- E Giraldo,
- P Krogsgaard-Larsen,
- and S J Enna
(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.
J Pharmacol Exp Ther July 1987 242:173-178
- Abstract
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- J L Katz and
- S R Goldberg
Psychomotor stimulant effects of caffeine alone and in combination with an adenosine analog in the squirrel monkey.
J Pharmacol Exp Ther July 1987 242:179-187
- Abstract
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- R M Rapoport
Effects of norepinephrine on contraction and hydrolysis of phosphatidylinositols in rat aorta.
J Pharmacol Exp Ther July 1987 242:188-194
- Abstract
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- C P France and
- J H Woods
Morphine, saline and naltrexone discrimination in morphine-treated pigeons.
J Pharmacol Exp Ther July 1987 242:195-202
- Abstract
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- P M Beardsley and
- R L Balster
Behavioral dependence upon phencyclidine and ketamine in the rat.
J Pharmacol Exp Ther July 1987 242:203-211
- Abstract
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- J A Gray and
- R J Kavlock
Pharmacologic probing of mercuric chloride-induced renal dysfunction in the neonatal rat.
J Pharmacol Exp Ther July 1987 242:212-216
- Abstract
- Full Text (PDF)
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- N Aiyar,
- P Nambi,
- F L Stassen,
- and S T Crooke
Effects of N-ethylmaleimide on arginine vasopressin-induced responses in an established smooth muscle cell line.
J Pharmacol Exp Ther July 1987 242:217-221
- Abstract
- Full Text (PDF)
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- B I Ghanayem,
- L T Burka,
- and H B Matthews
Metabolic basis of ethylene glycol monobutyl ether (2-butoxyethanol) toxicity: role of alcohol and aldehyde dehydrogenases.
J Pharmacol Exp Ther July 1987 242:222-231
- Abstract
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- T A Slotkin,
- L Orband-Miller,
- and K L Queen
Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions.
J Pharmacol Exp Ther July 1987 242:232-237
- Abstract
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- J Xu and
- D M Chuang
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists.
J Pharmacol Exp Ther July 1987 242:238-244
- Abstract
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- D C Stump,
- L Kieckens,
- F De Cock,
- and D Collen
Pharmacokinetics of single chain forms of urokinase-type plasminogen activator.
J Pharmacol Exp Ther July 1987 242:245-250
- Abstract
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- E Hovav and
- M Weinstock
Temporal factors influencing the development of acute tolerance to opiates.
J Pharmacol Exp Ther July 1987 242:251-256
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- H N Doods,
- M J Mathy,
- D Davidesko,
- K J van Charldorp,
- A de Jonge,
- and P A van Zwieten
Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.
J Pharmacol Exp Ther July 1987 242:257-262
- Abstract
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- Z Terashita,
- Y Imura,
- M Takatani,
- S Tsushima,
- and K Nishikawa
CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo.
J Pharmacol Exp Ther July 1987 242:263-268
- Abstract
- Full Text (PDF)
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- I Muramatsu,
- M Noda,
- M Nishio,
- and M Fujiwara
Mechanism of sodium channel block in crayfish giant axons by 711389-S, a new antiarrhythmic drug.
J Pharmacol Exp Ther July 1987 242:269-276
- Abstract
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- M Seiler and
- D G Weiss
Nocodazole irreversibly reduces the capacity of rapid axoplasmic transport in vitro.
J Pharmacol Exp Ther July 1987 242:277-283
- Abstract
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- G R Bolt,
- H Itoh,
- K Lederis,
- and K L MacCannell
Differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by urotensin I, a selective mesenteric vasodilator peptide.
J Pharmacol Exp Ther July 1987 242:284-291
- Abstract
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- M P Moffat
Concentration-dependent effects of prostacyclin on the response of the isolated guinea pig heart to ischemia and reperfusion: possible involvement of the slow inward current.
J Pharmacol Exp Ther July 1987 242:292-299
- Abstract
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- S Consolo,
- C F Wu,
- and R Fusi
D-1 receptor-linked mechanism modulates cholinergic neurotransmission in rat striatum.
J Pharmacol Exp Ther July 1987 242:300-305
- Abstract
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- S Narumiya,
- K Ohno,
- M Fukushima,
- and M Fujiwara
Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei.
J Pharmacol Exp Ther July 1987 242:306-311
- Abstract
- Full Text (PDF)
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- M D Threadgill,
- D B Axworthy,
- T A Baillie,
- P B Farmer,
- K C Farrow,
- A Gescher,
- P Kestell,
- P G Pearson,
- and A J Shaw
Metabolism of N-methylformamide in mice: primary kinetic deuterium isotope effect and identification of S-(N-methylcarbamoyl)glutathione as a metabolite.
J Pharmacol Exp Ther July 1987 242:312-319
- Abstract
- Full Text (PDF)
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- C Lambert,
- R Cardinal,
- M Vermeulen,
- D Lamontagne,
- R Nadeau,
- P Paradis,
- and J L Rouleau
Lack of relation between the ventricular refractory period prolongation by amiodarone and the thyroid state in rats.
J Pharmacol Exp Ther July 1987 242:320-325
- Abstract
- Full Text (PDF)
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- S Yamada,
- N Ashizawa,
- H Ushijima,
- K Nakayama,
- E Hayashi,
- and K Honda
Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy.
J Pharmacol Exp Ther July 1987 242:326-330
- Abstract
- Full Text (PDF)
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- B S Gan,
- M D Hollenberg,
- K L MacCannell,
- K Lederis,
- M E Winkler,
- and R Derynck
Distinct vascular actions of epidermal growth factor-urogastrone and transforming growth factor-alpha.
J Pharmacol Exp Ther July 1987 242:331-337
- Abstract
- Full Text (PDF)
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- S Marleau,
- H Ong,
- L Gariépy,
- and P du Souich
Lidocaine and indocyanine green kinetics: effect of hypoxemia and/or hypercapnia.
J Pharmacol Exp Ther July 1987 242:338-343
- Abstract
- Full Text (PDF)
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- D L Graham and
- P Skett
Endocrine regulation of the metabolism of 1-naphthol in the rat.
J Pharmacol Exp Ther July 1987 242:344-348
- Abstract
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- S Urien,
- J L Pinquier,
- B Paquette,
- P Chaumet-Riffaud,
- J R Kiechel,
- and J P Tillement
Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug.
J Pharmacol Exp Ther July 1987 242:349-353
- Abstract
- Full Text (PDF)
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- P Haddad,
- P A Coulombe,
- and M Gascon-Barré
Influence of the vitamin D hormonal status on the hepatic response to bromobenzene.
J Pharmacol Exp Ther July 1987 242:354-363
- Abstract
- Full Text (PDF)
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- R J D'Amato,
- B L Largent,
- A M Snowman,
- and S H Snyder
Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine.
J Pharmacol Exp Ther July 1987 242:364-371
- Abstract
- Full Text (PDF)
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- L F Chuang,
- R Y Chuang,
- E M Acton,
- M Israel,
- and M Yu
Effect of morpholinyladriamycin analogs and adriamycin on the activities of DNA polymerase alpha and RNA polymerase II of chicken leukemia cells.
J Pharmacol Exp Ther July 1987 242:372-377
- Abstract
- Full Text (PDF)
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- J A Mastrianni and
- A J Ingenito
On the relationship between clonidine hypotension and brain beta-endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers.
J Pharmacol Exp Ther July 1987 242:378-387
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Mu opioid antagonist properties of a cyclic somatostatin octapeptide in vivo: identification of mu receptor-related functions.

Potentiation of the protective effects of a converting enzyme inhibitor and a thromboxane synthetase inhibitor in hemorrhagic shock.

Naloxonazine effects on the interaction of enkephalin analogs with mu-1, mu and delta opioid binding sites in rat brain membranes.

Human lymphocyte thiopurine methyltransferase pharmacogenetics: effect of phenotype on 6-mercaptopurine-induced inhibition of mitogen stimulation.

Effect of inhibition of gamma-glutamyltranspeptidase on biliary and urinary excretion of glutathione-derived thiols and methylmercury.

Kappa agonist-induced diuresis: evidence for stereoselectivity, strain differences, independence of hydration variables and a result of decreased plasma vasopressin levels.

Repeated amphetamine pretreatment alters the responsiveness of striatal dopamine-stimulated adenylate cyclase to amphetamine-induced desensitization.

CGS 9896 and ZK 91296, but not CGS 8216 and RO 15-1788, are pure benzodiazepine receptor antagonists on mouse neurons in culture.

Ryanodine: antithetical calcium channel effects in skeletal muscle sarcoplasmic reticulum.

Primate myocardial and systemic hemodynamic responses to leukotriene D4: antagonism by LY171883.

Antidotal use of methemoglobin forming cyanide antagonists in concurrent carbon monoxide/cyanide intoxication.

Preclinical evaluation of McN-5707 as a potential antidepressant.

Diuretic-induced growth failure in rats and its reversal by sodium repletion.

Central and systemic morphine-induced antinociception in mice: contribution of descending serotonergic and noradrenergic pathways.

Phencyclidine pharmacokinetic scaling among species.

Effects of propranolol on regional O2 supply and O2 consumption in reperfused dog myocardium.

Kinetics of competitive drug action at 5-hydroxytryptamine2 receptors in isolated rabbit aorta.

Dopamine autoreceptors modulate the in vivo release of dopamine in the frontal, cingulate and entorhinal cortices.

Asymmetric catecholimidazolines and catecholamidines: affinity and efficacy relationships at the alpha adrenoreceptor in rat aorta.

Intrathecal administration of a substance P receptor antagonist: studies on peripheral and central nervous system hemodynamics and on specificity of action.

A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage.

Role of vasopressin in the cardiovascular effects of LY171555, a selective dopamine D2 receptor agonist: studies in conscious Brattleboro and Long-Evans rats.

The neurotoxins 1-methyl-4-phenylpyridinium and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine are substrates for the organic cation transporter in renal brush border membrane vesicles.

Enhanced pulmonary alpha-2 adrenoceptor responsiveness under conditions of elevated pulmonary vascular tone.

Kinetics of drug action in disease states. XX. Effects of acute starvation on the pharmacodynamics of phenobarbital, ethanol and pentylenetetrazol in rats and effects of refeeding and diet composition.

(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.

Psychomotor stimulant effects of caffeine alone and in combination with an adenosine analog in the squirrel monkey.

Effects of norepinephrine on contraction and hydrolysis of phosphatidylinositols in rat aorta.

Morphine, saline and naltrexone discrimination in morphine-treated pigeons.

Behavioral dependence upon phencyclidine and ketamine in the rat.

Pharmacologic probing of mercuric chloride-induced renal dysfunction in the neonatal rat.

Effects of N-ethylmaleimide on arginine vasopressin-induced responses in an established smooth muscle cell line.

Metabolic basis of ethylene glycol monobutyl ether (2-butoxyethanol) toxicity: role of alcohol and aldehyde dehydrogenases.

Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions.

Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists.

Pharmacokinetics of single chain forms of urokinase-type plasminogen activator.

Temporal factors influencing the development of acute tolerance to opiates.

Selectivity of muscarinic antagonists in radioligand and in vivo experiments for the putative M1, M2 and M3 receptors.

CV-6209, a highly potent antagonist of platelet activating factor in vitro and in vivo.

Mechanism of sodium channel block in crayfish giant axons by 711389-S, a new antiarrhythmic drug.

Nocodazole irreversibly reduces the capacity of rapid axoplasmic transport in vitro.

Differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by urotensin I, a selective mesenteric vasodilator peptide.

Concentration-dependent effects of prostacyclin on the response of the isolated guinea pig heart to ischemia and reperfusion: possible involvement of the slow inward current.

D-1 receptor-linked mechanism modulates cholinergic neurotransmission in rat striatum.

Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei.

Metabolism of N-methylformamide in mice: primary kinetic deuterium isotope effect and identification of S-(N-methylcarbamoyl)glutathione as a metabolite.

Lack of relation between the ventricular refractory period prolongation by amiodarone and the thyroid state in rats.

Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy.

Distinct vascular actions of epidermal growth factor-urogastrone and transforming growth factor-alpha.

Lidocaine and indocyanine green kinetics: effect of hypoxemia and/or hypercapnia.

Endocrine regulation of the metabolism of 1-naphthol in the rat.

Effect of the binding of isradipine and darodipine to different plasma proteins on their transfer through the rat blood-brain barrier. Drug binding to lipoproteins does not limit the transfer of drug.

Influence of the vitamin D hormonal status on the hepatic response to bromobenzene.

Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine.

Effect of morpholinyladriamycin analogs and adriamycin on the activities of DNA polymerase alpha and RNA polymerase II of chicken leukemia cells.

On the relationship between clonidine hypotension and brain beta-endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers.

This Issue

Current Issue