Table of Contents

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- J M Roesler,
- J P McCafferty,
- R M DeMarinis,
- W D Matthews,
- and J P Hieble
Characterization of the antihypertensive activity of SK&F 86466, a selective alpha-2 antagonist, in the rat.
J Pharmacol Exp Ther January 1986 236:1-7
- Abstract
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- D E Gmerek,
- A Cowan,
- and J H Woods
Independent central and peripheral mediation of morphine-induced inhibition of gastrointestinal transit in rats.
J Pharmacol Exp Ther January 1986 236:8-13
- Abstract
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- B I Hirschowitz
Desensitization within and between secretagogues of canine gastric acid and pepsin secretion.
J Pharmacol Exp Ther January 1986 236:14-23
- Abstract
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- J A Severson,
- R N Pittman,
- J Gal,
- P B Molinoff,
- and C E Finch
Genetic influence on the regulation of beta adrenergic receptors in mice.
J Pharmacol Exp Ther January 1986 236:24-29
- Abstract
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- L J Ignarro,
- R G Harbison,
- K S Wood,
- and P J Kadowitz
Dissimilarities between methylene blue and cyanide on relaxation and cyclic GMP formation in endothelium-intact intrapulmonary artery caused by nitrogen oxide-containing vasodilators and acetylcholine.
J Pharmacol Exp Ther January 1986 236:30-36
- Abstract
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- S A Knizner,
- A J Jacobs,
- R C Lyon,
- and C E Swenberg
In vivo dephosphorylation of WR-2721 monitored by 31P NMR spectroscopy.
J Pharmacol Exp Ther January 1986 236:37-40
- Abstract
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- K Kanda and
- S F Flaim
Effects of nimodipine on cerebral blood flow in conscious rat.
J Pharmacol Exp Ther January 1986 236:41-47
- Abstract
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- R N Cory,
- R Osman,
- and S Maayani
Kinetic definition of agonist efficacy at a 5-hydroxytryptamine (5-HT2) receptor in the isolated rabbit aorta.
J Pharmacol Exp Ther January 1986 236:48-54
- Abstract
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- C A Heyneman and
- M J Reasor
Role of the alveolar macrophage in the induction of pulmonary phospholipidosis by chlorphentermine. I. Drug and phospholipid levels.
J Pharmacol Exp Ther January 1986 236:55-59
- Abstract
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- C A Heyneman and
- M J Reasor
Role of the alveolar macrophage in the induction of pulmonary phospholipidosis by chlorphentermine. II. Drug uptake into cells in vitro.
J Pharmacol Exp Ther January 1986 236:60-64
- Abstract
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- M H Sabouni,
- K A Alkadhi,
- and M F Lokhandwala
Pharmacological characterization of dopamine receptors in the stellate ganglia with selective DA1 and DA2 receptor agonists and antagonists.
J Pharmacol Exp Ther January 1986 236:65-70
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- S P Duckles and
- J S Hurlbert
Effect of age on beta adrenergic relaxation of the rat jugular vein.
J Pharmacol Exp Ther January 1986 236:71-74
- Abstract
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- G R Hageman,
- B H Neely,
- F Urthaler,
- and L V Rosenshtraukh
Effects of the diethylamino analog of ethmozin (ethacizin) upon sympathetic and parasympathetic efferent activity to the canine heart.
J Pharmacol Exp Ther January 1986 236:75-79
- Abstract
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- K Ramos,
- W T Gerthoffer,
- and D P Westfall
Denervation-induced supersensitivity to calcium of chemically skinned smooth muscle of the guinea-pig vas deferens.
J Pharmacol Exp Ther January 1986 236:80-84
- Abstract
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- R K Gordon and
- P K Chiang
Antimuscarinic activities of hycanthone analogs: possible relationship with animal toxicity.
J Pharmacol Exp Ther January 1986 236:85-89
- Abstract
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- J P Hieble,
- R M DeMarinis,
- P J Fowler,
- and W D Matthews
Selective alpha-2 adrenoceptor blockade by SK&F 86466: in vitro characterization of receptor selectivity.
J Pharmacol Exp Ther January 1986 236:90-96
- Abstract
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- R M Fielding,
- J A Waschek,
- D J Effeney,
- A C Pogany,
- S M Pond,
- and T N Tozer
Extrahepatic extraction of salicylamide in dogs.
J Pharmacol Exp Ther January 1986 236:97-102
- Abstract
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- M J DiMartino,
- J C Lee,
- A M Badger,
- K A Muirhead,
- C K Mirabelli,
- and N Hanna
Antiarthritic and immunoregulatory activity of spirogermanium.
J Pharmacol Exp Ther January 1986 236:103-110
- Abstract
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- G F Steinfels and
- L Cook
Antinociceptive profiles of mu and kappa opioid agonists in a rat tooth pulp stimulation procedure.
J Pharmacol Exp Ther January 1986 236:111-117
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- E W Taylor,
- S P Duckles,
- and D L Nelson
Dissociation constants of serotonin agonists in the canine basilar artery correlate to Ki values at the 5-HT1A binding site.
J Pharmacol Exp Ther January 1986 236:118-125
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- J B Cheng,
- E I Cheng,
- F Kohi,
- and R G Townley
[3H]leukotriene B4 binding to the guinea-pig spleen membrane preparation: a rich tissue source for a high-affinity leukotriene B4 receptor site.
J Pharmacol Exp Ther January 1986 236:126-132
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- R E Galinsky
Role of glutathione turnover in drug sulfation: differential effects of diethylmaleate and buthionine sulfoximine on the pharmacokinetics of acetaminophen in the rat.
J Pharmacol Exp Ther January 1986 236:133-139
- Abstract
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- J S Loredo,
- R R Gonzalez, Jr,
- and D A Hessinger
Effect of Portuguese man-of-war venom on isolated vascular segments.
J Pharmacol Exp Ther January 1986 236:140-143
- Abstract
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- C Harris,
- R M Philpot,
- O Hernandez,
- and J R Bend
Rabbit pulmonary cytochrome P-450 monooxygenase system: isozyme differences in the rate and stereoselectivity of styrene oxidation.
J Pharmacol Exp Ther January 1986 236:144-149
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- J T Hjelle,
- G A Hazelton,
- C D Klaassen,
- and J J Hjelle
Glucuronidation and sulfation in rabbit kidney.
J Pharmacol Exp Ther January 1986 236:150-156
- Abstract
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- B S Neal and
- S B Sparber
Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine.
J Pharmacol Exp Ther January 1986 236:157-165
- Abstract
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- Z S Katusic,
- J T Shepherd,
- and P M Vanhoutte
Oxytocin causes endothelium-dependent relaxations of canine basilar arteries by activating V1-vasopressinergic receptors.
J Pharmacol Exp Ther January 1986 236:166-170
- Abstract
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- M K Ahlijanian and
- A E Takemori
Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.
J Pharmacol Exp Ther January 1986 236:171-176
- Abstract
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- J F Valentine,
- D C Brater,
- and G J Krejs
Clearance of furosemide by the gastrointestinal tract.
J Pharmacol Exp Ther January 1986 236:177-180
- Abstract
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- Y Vulliemoz,
- M Verosky,
- and L Triner
Effect of halothane on myocardial cyclic AMP and cyclic GMP content of mice.
J Pharmacol Exp Ther January 1986 236:181-186
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- R W Lappe,
- J A Todt,
- and R L Wendt
Effects of fenoldopam on regional vascular resistance in conscious spontaneously hypertensive rats.
J Pharmacol Exp Ther January 1986 236:187-191
- Abstract
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- A Sawamura,
- N Sperelakis,
- J Azuma,
- H Harada,
- and K Fukuda
Stimulation of cardiac slow Ca++ current by high concentration of cimetidine.
J Pharmacol Exp Ther January 1986 236:192-196
- Abstract
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- R A Jensen
Doxorubicin cardiotoxicity: contractile changes after long-term treatment in the rat.
J Pharmacol Exp Ther January 1986 236:197-203
- Abstract
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- C E Jones,
- I Y Liang,
- and M R Maulsby
Cardiac and coronary effects of prazosin and phenoxybenzamine during coronary hypotension.
J Pharmacol Exp Ther January 1986 236:204-211
- Abstract
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- R L Panek,
- R R Gaddis,
- and W R Dixon
Effects of ouabain on the nerve stimulation-evoked release of norepinephrine from the isolated perfused guinea-pig heart.
J Pharmacol Exp Ther January 1986 236:212-218
- Abstract
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- J Nedoma,
- S Tucek,
- A F Danilov,
- and S A Shelkovnikov
Stabilization of antagonist binding to cardiac muscarinic acetylcholine receptors by gallamine and other neuromuscular blocking drugs.
J Pharmacol Exp Ther January 1986 236:219-223
- Abstract
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- R Segstro and
- C Greenway
Alpha adrenoceptor subtype mediating sympathetic mobilization of blood from the hepatic venous system in anesthetized cats.
J Pharmacol Exp Ther January 1986 236:224-229
- Abstract
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- L Beani,
- S Tanganelli,
- T Antonelli,
- and C Bianchi
Noradrenergic modulation of cortical acetylcholine release is both direct and gamma-aminobutyric acid-mediated.
J Pharmacol Exp Ther January 1986 236:230-236
- Abstract
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- H Fouin-Fortunet,
- M Tinel,
- V Descatoire,
- P Letteron,
- D Larrey,
- J Geneve,
- and D Pessayre
Inactivation of cytochrome P-450 by the drug methoxsalen.
J Pharmacol Exp Ther January 1986 236:237-247
- Abstract
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- J Fryklund and
- B Wallmark
Sulfide and sulfoxide derivatives of substituted benzimidazoles inhibit acid formation in isolated gastric glands by different mechanisms.
J Pharmacol Exp Ther January 1986 236:248-253
- Abstract
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- D W Schwertz,
- J I Kreisberg,
- and M A Venkatachalam
Gentamicin-induced alterations in pig kidney epithelial (LLC-PK1) cells in culture.
J Pharmacol Exp Ther January 1986 236:254-262
- Abstract
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- B U Bradford,
- M Marotto,
- J J Lemasters,
- and R G Thurman
New, simple models to evaluate zone-specific damage due to hypoxia in the perfused rat liver: time course and effect of nutritional state.
J Pharmacol Exp Ther January 1986 236:263-268
- Abstract
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- T Cresteil,
- P Beaune,
- C Celier,
- J P Leroux,
- and F P Guengerich
Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene.
J Pharmacol Exp Ther January 1986 236:269-276
- Abstract
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- J M Whaun,
- G A Miura,
- N D Brown,
- R K Gordon,
- and P K Chiang
Antimalarial activity of neplanocin A with perturbations in the metabolism of purines, polyamines and S-adenosylmethionine.
J Pharmacol Exp Ther January 1986 236:277-283
- Abstract
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- E I Tietz,
- H C Rosenberg,
- and T H Chiu
Autoradiographic localization of benzodiazepine receptor downregulation.
J Pharmacol Exp Ther January 1986 236:284-292
- Abstract
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- A H Ganong and
- C W Cotman
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
J Pharmacol Exp Ther January 1986 236:293-299
- Abstract
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ERRATUM
J Pharmacol Exp Ther January 1986 236:300
- Abstract
- Full Text (PDF)

Characterization of the antihypertensive activity of SK&F 86466, a selective alpha-2 antagonist, in the rat.

Independent central and peripheral mediation of morphine-induced inhibition of gastrointestinal transit in rats.

Desensitization within and between secretagogues of canine gastric acid and pepsin secretion.

Genetic influence on the regulation of beta adrenergic receptors in mice.

Dissimilarities between methylene blue and cyanide on relaxation and cyclic GMP formation in endothelium-intact intrapulmonary artery caused by nitrogen oxide-containing vasodilators and acetylcholine.

In vivo dephosphorylation of WR-2721 monitored by 31P NMR spectroscopy.

Effects of nimodipine on cerebral blood flow in conscious rat.

Kinetic definition of agonist efficacy at a 5-hydroxytryptamine (5-HT2) receptor in the isolated rabbit aorta.

Role of the alveolar macrophage in the induction of pulmonary phospholipidosis by chlorphentermine. I. Drug and phospholipid levels.

Role of the alveolar macrophage in the induction of pulmonary phospholipidosis by chlorphentermine. II. Drug uptake into cells in vitro.

Pharmacological characterization of dopamine receptors in the stellate ganglia with selective DA1 and DA2 receptor agonists and antagonists.

Effect of age on beta adrenergic relaxation of the rat jugular vein.

Effects of the diethylamino analog of ethmozin (ethacizin) upon sympathetic and parasympathetic efferent activity to the canine heart.

Denervation-induced supersensitivity to calcium of chemically skinned smooth muscle of the guinea-pig vas deferens.

Antimuscarinic activities of hycanthone analogs: possible relationship with animal toxicity.

Selective alpha-2 adrenoceptor blockade by SK&F 86466: in vitro characterization of receptor selectivity.

Extrahepatic extraction of salicylamide in dogs.

Antiarthritic and immunoregulatory activity of spirogermanium.

Antinociceptive profiles of mu and kappa opioid agonists in a rat tooth pulp stimulation procedure.

Dissociation constants of serotonin agonists in the canine basilar artery correlate to Ki values at the 5-HT1A binding site.

[3H]leukotriene B4 binding to the guinea-pig spleen membrane preparation: a rich tissue source for a high-affinity leukotriene B4 receptor site.

Role of glutathione turnover in drug sulfation: differential effects of diethylmaleate and buthionine sulfoximine on the pharmacokinetics of acetaminophen in the rat.

Effect of Portuguese man-of-war venom on isolated vascular segments.

Rabbit pulmonary cytochrome P-450 monooxygenase system: isozyme differences in the rate and stereoselectivity of styrene oxidation.

Glucuronidation and sulfation in rabbit kidney.

Mianserin attenuates naloxone-precipitated withdrawal signs in rats acutely or chronically dependent upon morphine.

Oxytocin causes endothelium-dependent relaxations of canine basilar arteries by activating V1-vasopressinergic receptors.

Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.

Clearance of furosemide by the gastrointestinal tract.

Effect of halothane on myocardial cyclic AMP and cyclic GMP content of mice.

Effects of fenoldopam on regional vascular resistance in conscious spontaneously hypertensive rats.

Stimulation of cardiac slow Ca++ current by high concentration of cimetidine.

Doxorubicin cardiotoxicity: contractile changes after long-term treatment in the rat.

Cardiac and coronary effects of prazosin and phenoxybenzamine during coronary hypotension.

Effects of ouabain on the nerve stimulation-evoked release of norepinephrine from the isolated perfused guinea-pig heart.

Stabilization of antagonist binding to cardiac muscarinic acetylcholine receptors by gallamine and other neuromuscular blocking drugs.

Alpha adrenoceptor subtype mediating sympathetic mobilization of blood from the hepatic venous system in anesthetized cats.

Noradrenergic modulation of cortical acetylcholine release is both direct and gamma-aminobutyric acid-mediated.

Inactivation of cytochrome P-450 by the drug methoxsalen.

Sulfide and sulfoxide derivatives of substituted benzimidazoles inhibit acid formation in isolated gastric glands by different mechanisms.

Gentamicin-induced alterations in pig kidney epithelial (LLC-PK1) cells in culture.

New, simple models to evaluate zone-specific damage due to hypoxia in the perfused rat liver: time course and effect of nutritional state.

Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene.

Antimalarial activity of neplanocin A with perturbations in the metabolism of purines, polyamines and S-adenosylmethionine.

Autoradiographic localization of benzodiazepine receptor downregulation.

Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.

Article

ERRATUM

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