Table of Contents

September 1984; 230 (3)

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- S Hayashi and
- M K Park
Neurogenic and myogenic contractile responses of dog mesenteric arteries to reduced K+ concentration and their interactions with ouabain.
J Pharmacol Exp Ther September 1984 230:527-533
- Abstract
- Full Text (PDF)
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- R I Fishleder and
- C K Buckner
Studies on the relationship between contraction and mediator release produced by ovalbumin in superfused trachea isolated from the actively sensitized guinea pig.
J Pharmacol Exp Ther September 1984 230:534-540
- Abstract
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- J M Moerschbaecher,
- J Mastropaolo,
- P J Winsauer,
- and D M Thompson
Effects of opioids on accuracy of a fixed-ratio discrimination in monkeys and rats.
J Pharmacol Exp Ther September 1984 230:541-549
- Abstract
- Full Text (PDF)
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- L E Rinkema,
- K G Bemis,
- and J H Fleisch
Production and antagonism of cutaneous vascular permeability in the guinea pig in response to histamine, leukotrienes and A23187.
J Pharmacol Exp Ther September 1984 230:550-557
- Abstract
- Full Text (PDF)
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- R A Hahn and
- B R MacDonald
Systemic hemodynamic and regional blood flow effects of LY141865, a selective dopamine receptor agonist.
J Pharmacol Exp Ther September 1984 230:558-568
- Abstract
- Full Text (PDF)
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- G E Martin,
- M Williams,
- D J Pettibone,
- G G Yarbrough,
- B V Clineschmidt,
- and J H Jones
Pharmacologic profile of a novel potent direct-acting dopamine agonist, (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO].
J Pharmacol Exp Ther September 1984 230:569-576
- Abstract
- Full Text (PDF)
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- J M Stolk,
- G Vantini,
- B D Perry,
- R B Guchhait,
- and D C U'Prichard
Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism.
J Pharmacol Exp Ther September 1984 230:577-586
- Abstract
- Full Text (PDF)
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- R R Ruffolo, Jr,
- E L Morgan,
- and K Messick
Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.
J Pharmacol Exp Ther September 1984 230:587-594
- Abstract
- Full Text (PDF)
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- R R Ruffolo, Jr,
- M R Goldberg,
- and E L Morgan
Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.
J Pharmacol Exp Ther September 1984 230:595-600
- Abstract
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- T O Pitts,
- J H Dominguez,
- and J B Puschett
Interference by prostaglandin E2 with the phosphaturic effects of nonhormonal agents.
J Pharmacol Exp Ther September 1984 230:601-606
- Abstract
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- E M Luchowski,
- F Yousif,
- D J Triggle,
- S C Maurer,
- J G Sarmiento,
- and R A Janis
Effects of metal cations and calmodulin antagonists on [3H] nitrendipine binding in smooth and cardiac muscle.
J Pharmacol Exp Ther September 1984 230:607-613
- Abstract
- Full Text (PDF)
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- R N Pittman,
- E E Reynolds,
- and P B Molinoff
Relationship between intrinsic activities of agonists in normal and desensitized tissue and agonist-induced loss of beta adrenergic receptors.
J Pharmacol Exp Ther September 1984 230:614-618
- Abstract
- Full Text (PDF)
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- M A Maleque,
- K Takahashi,
- B Witkop,
- A Brossi,
- and E X Albuquerque
A study of the novel synthetic analog (+/-)-depentylperhydrohistrionicotoxin on the nicotinic receptor-ion channel complex.
J Pharmacol Exp Ther September 1984 230:619-626
- Abstract
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- M Danhof,
- M Hisaoka,
- and G Levy
Kinetics of drug action in disease states. II. Effect of experimental renal dysfunction on phenobarbital concentrations in rats at onset of loss of righting reflect.
J Pharmacol Exp Ther September 1984 230:627-631
- Abstract
- Full Text (PDF)
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- E Patterson,
- D G Montgomery,
- J J Lynch,
- and B R Lucchesi
Cardiac electrophysiologic actions of KB-944 (Fostedil), a new calcium antagonist, in the anesthetized dog.
J Pharmacol Exp Ther September 1984 230:632-640
- Abstract
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- G R Slizgi,
- C J Taylor,
- and J H Ludens
Effects of the highly selective kappa opioid, U-50, 488, on renal function in the anesthetized dog.
J Pharmacol Exp Ther September 1984 230:641-645
- Abstract
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- Y Hattori and
- R Levi
Negative inotropic effect of leukotrienes: leukotrienes C4 and D4 inhibit calcium-dependent contractile responses in potassium-depolarized guinea-pig myocardium.
J Pharmacol Exp Ther September 1984 230:646-651
- Abstract
- Full Text (PDF)
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- C P France,
- A E Jacobson,
- and J H Woods
Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine.
J Pharmacol Exp Ther September 1984 230:652-657
- Abstract
- Full Text (PDF)
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- H Marcucella,
- I Munro,
- and J S MacDonall
Patterns of ethanol consumption as a function of the schedule of ethanol access.
J Pharmacol Exp Ther September 1984 230:658-664
- Abstract
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- L L Simpson
Molecular basis for the pharmacological actions of Clostridium botulinum type C2 toxin.
J Pharmacol Exp Ther September 1984 230:665-669
- Abstract
- Full Text (PDF)
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- L B Katz,
- H M Theobald,
- R C Bookstaff,
- and R E Peterson
Characterization of the enhanced paw edema response to carrageenan and dextran in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.
J Pharmacol Exp Ther September 1984 230:670-677
- Abstract
- Full Text (PDF)
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- W L Woolverton,
- L I Goldberg,
- and J Z Ginos
Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.
J Pharmacol Exp Ther September 1984 230:678-683
- Abstract
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- S R Childers
Interaction of opiate receptor binding sites and guanine nucleotide regulatory sites: selective protection from N-ethylmaleimide.
J Pharmacol Exp Ther September 1984 230:684-691
- Abstract
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- G Rubanyi and
- R J Paul
O2-sensitivity of beta adrenergic responsiveness in isolated bovine and porcine coronary arteries.
J Pharmacol Exp Ther September 1984 230:692-698
- Abstract
- Full Text (PDF)
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- N A Flavahan,
- T J Rimele,
- J P Cooke,
- and P M Vanhoutte
Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein.
J Pharmacol Exp Ther September 1984 230:699-705
- Abstract
- Full Text (PDF)
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- L P Rybak,
- T P Green,
- S K Juhn,
- and T Morizono
Probenecid reduces cochlear effects and perilymph penetration of furosemide in chinchilla.
J Pharmacol Exp Ther September 1984 230:706-709
- Abstract
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- J A Hirsch
Structure-activity relationship between guanidine alkyl derivatives and norepinephrine release: site(s) and mechanism(s) of action.
J Pharmacol Exp Ther September 1984 230:710-717
- Abstract
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- A B Ahmad,
- P N Bennett,
- and M Rowland
Influence of route of hepatic administration on drug availability.
J Pharmacol Exp Ther September 1984 230:718-725
- Abstract
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- R Hori,
- K Yamamoto,
- H Saito,
- M Kohno,
- and K Inui
Effect of aminoglycoside antibiotics on cellular functions of kidney epithelial cell line (LLC-PK1): a model system for aminoglycoside nephrotoxicity.
J Pharmacol Exp Ther September 1984 230:724-728
- Abstract
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- H A Strong,
- J Oates,
- J Sembi,
- A G Renwick,
- and C F George
Role of the gut flora in the reduction of sulfinpyrazone in humans.
J Pharmacol Exp Ther September 1984 230:726-732
- Abstract
- Full Text (PDF)
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- L Illum,
- P D Jones,
- R W Baldwin,
- and S S Davis
Tissue distribution of poly(hexyl 2-cyanoacrylate) nanoparticles coated with monoclonal antibodies in mice bearing human tumor xenografts.
J Pharmacol Exp Ther September 1984 230:733-736
- Abstract
- Full Text (PDF)
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- H Itoh,
- T Ishikawa,
- and H Hidaka
Effects on calmodulin of bepridil, an antianginal agent.
J Pharmacol Exp Ther September 1984 230:737-741
- Abstract
- Full Text (PDF)
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- F Marceau and
- T E Hugli
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
J Pharmacol Exp Ther September 1984 230:749-754
- Abstract
- Full Text (PDF)
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- S A Belinsky,
- J A Popp,
- F C Kauffman,
- and R G Thurman
Trypan blue uptake as a new method to investigate hepatotoxicity in periportal and pericentral regions of the liver lobule: studies with allyl alcohol in the perfused liver.
J Pharmacol Exp Ther September 1984 230:755-760
- Abstract
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- K T Shiverick,
- E Ortiz,
- C Fuhrman-Lane,
- and P Crowley
Effects of beta-naphthoflavone and 3-methylcholanthrene administered to pregnant rats on steroid metabolism in the isolated basal zone of the placenta.
J Pharmacol Exp Ther September 1984 230:761-767
- Abstract
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- H S Pan,
- J B Penney, Jr,
- and A B Young
Characterization of benzodiazepine receptor changes in substantia nigra, globus pallidus and entopeduncular nucleus after striatal lesions.
J Pharmacol Exp Ther September 1984 230:768-775
- Abstract
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Article

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- RYOHEI HORI,
- KYOKO YAMAMOTO,
- HIDEYUKI SAITO,
- MICHIAKI KOHNO,
- and KEN-ICHI INUI
Effect of Aminoglycoside Antibiotics on Cellular Functions of Kidney Epithelial Cell Line (LLC-PK₁): A Model System for Aminoglycoside Nephrotoxicity
J Pharmacol Exp Ther September 1984 230:742-748
- Abstract
- Full Text (PDF)

Current Issue

November 2009, 331 (2)

Neurogenic and myogenic contractile responses of dog mesenteric arteries to reduced K+ concentration and their interactions with ouabain.

Studies on the relationship between contraction and mediator release produced by ovalbumin in superfused trachea isolated from the actively sensitized guinea pig.

Effects of opioids on accuracy of a fixed-ratio discrimination in monkeys and rats.

Production and antagonism of cutaneous vascular permeability in the guinea pig in response to histamine, leukotrienes and A23187.

Systemic hemodynamic and regional blood flow effects of LY141865, a selective dopamine receptor agonist.

Pharmacologic profile of a novel potent direct-acting dopamine agonist, (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO].

Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism.

Possible relationship between receptor reserve and the differential antagonism of alpha-1 and alpha-2 adrenoceptor-mediated pressor responses by calcium channel antagonists in the pithed rat.

Interactions of epinephrine, norepinephrine, dopamine and their corresponding alpha-methyl-substituted derivatives with alpha and beta adrenoceptors in the pithed rat.

Interference by prostaglandin E2 with the phosphaturic effects of nonhormonal agents.

Effects of metal cations and calmodulin antagonists on [3H] nitrendipine binding in smooth and cardiac muscle.

Relationship between intrinsic activities of agonists in normal and desensitized tissue and agonist-induced loss of beta adrenergic receptors.

A study of the novel synthetic analog (+/-)-depentylperhydrohistrionicotoxin on the nicotinic receptor-ion channel complex.

Kinetics of drug action in disease states. II. Effect of experimental renal dysfunction on phenobarbital concentrations in rats at onset of loss of righting reflect.

Cardiac electrophysiologic actions of KB-944 (Fostedil), a new calcium antagonist, in the anesthetized dog.

Effects of the highly selective kappa opioid, U-50, 488, on renal function in the anesthetized dog.

Negative inotropic effect of leukotrienes: leukotrienes C4 and D4 inhibit calcium-dependent contractile responses in potassium-depolarized guinea-pig myocardium.

Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine.

Patterns of ethanol consumption as a function of the schedule of ethanol access.

Molecular basis for the pharmacological actions of Clostridium botulinum type C2 toxin.

Characterization of the enhanced paw edema response to carrageenan and dextran in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.

Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.

Interaction of opiate receptor binding sites and guanine nucleotide regulatory sites: selective protection from N-ethylmaleimide.

O2-sensitivity of beta adrenergic responsiveness in isolated bovine and porcine coronary arteries.

Characterization of postjunctional alpha-1 and alpha-2 adrenoceptors activated by exogenous or nerve-released norepinephrine in the canine saphenous vein.

Probenecid reduces cochlear effects and perilymph penetration of furosemide in chinchilla.

Structure-activity relationship between guanidine alkyl derivatives and norepinephrine release: site(s) and mechanism(s) of action.

Influence of route of hepatic administration on drug availability.

Effect of aminoglycoside antibiotics on cellular functions of kidney epithelial cell line (LLC-PK1): a model system for aminoglycoside nephrotoxicity.

Role of the gut flora in the reduction of sulfinpyrazone in humans.

Tissue distribution of poly(hexyl 2-cyanoacrylate) nanoparticles coated with monoclonal antibodies in mice bearing human tumor xenografts.

Effects on calmodulin of bepridil, an antianginal agent.

Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.

Trypan blue uptake as a new method to investigate hepatotoxicity in periportal and pericentral regions of the liver lobule: studies with allyl alcohol in the perfused liver.

Effects of beta-naphthoflavone and 3-methylcholanthrene administered to pregnant rats on steroid metabolism in the isolated basal zone of the placenta.

Characterization of benzodiazepine receptor changes in substantia nigra, globus pallidus and entopeduncular nucleus after striatal lesions.

Article

Effect of Aminoglycoside Antibiotics on Cellular Functions of Kidney Epithelial Cell Line (LLC-PK1): A Model System for Aminoglycoside Nephrotoxicity

This Issue

Current Issue

Effect of Aminoglycoside Antibiotics on Cellular Functions of Kidney Epithelial Cell Line (LLC-PK₁): A Model System for Aminoglycoside Nephrotoxicity