Table of Contents

- K A Griffin,
- C B Johnson,
- R K Breger,
- and R B Franklin
Effects of inducers and inhibitors of cytochrome P-450-linked monooxygenases on the toxicity, in vitro metabolism and in vivo irreversible binding of 2-methylnaphthalene in mice.
J Pharmacol Exp Ther June 1982 221:517-524
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- R A Keith,
- A M Burkman,
- T D Sokoloski,
- and R H Fertel
Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle.
J Pharmacol Exp Ther June 1982 221:525-531
- Abstract
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- T V Zenser,
- N S Rapp,
- and B B Davis
Independent mechanisms for bradykinin-mediated prostaglandin E2 and cyclic GMP syntheses in rabbit renal inner medulla slices.
J Pharmacol Exp Ther June 1982 221:532-535
- Abstract
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- K K Vaccaro,
- B T Liang,
- B E Sheard,
- and R L Perlman
Monensin inhibits catecholamine synthesis in pheochromocytoma cells.
J Pharmacol Exp Ther June 1982 221:536-540
- Abstract
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- J F Reinhard, Jr and
- R H Roth
Noradrenergic modulation of serotonin synthesis and metabolism. I. Inhibition by clonidine in vivo.
J Pharmacol Exp Ther June 1982 221:541-546
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- M T Alderdice and
- J E McMillan
Comparison of the effects of trimethadione and its primary metabolite dimethadione on neuromuscular function and the effects of altered pH on the actions of dimethadione.
J Pharmacol Exp Ther June 1982 221:547-551
- Abstract
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- D M Roden,
- H J Duff,
- D Altenbern,
- and R L Woosley
Antiarrhythmic activity of the O-demethyl metabolite of encainide.
J Pharmacol Exp Ther June 1982 221:552-557
- Abstract
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- B A Faraj,
- F M Ali,
- J T Fulenwider,
- E J Malveaux,
- and W M Stacciarini
Hepatorenal failure induced by tetracycline in dogs with portacaval shunt.
J Pharmacol Exp Ther June 1982 221:558-563
- Abstract
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- K T Shiverick,
- A M Delorme,
- J G Scammell,
- and M J Fregly
Effects of chronic treatment with thyroxine and estradiol on estrogen concentration in serum and on hepatic microsomal catechol estrogen formation in female rats.
J Pharmacol Exp Ther June 1982 221:564-569
- Abstract
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- R L Volle,
- K A Alkadhi,
- D D Branisteanu,
- L S Reynolds,
- P M Epstein,
- H Smilowitz,
- J J Lambert,
- and E G Henderson
Ketamine and ditran block end-plate ion conductance and [3H]phencyclidine binding to electric organ membrane.
J Pharmacol Exp Ther June 1982 221:570-576
- Abstract
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- A S Israel,
- Y R Barbella,
- and L X Cubeddu
Effects of chemical sympathectomy on the increases in plasma catecholamines and dopamine-beta-hydroxylase induced by forced immobilization and insulin-induced hypoglycemia: origin and fate of plasma dopamine-beta-hydroxylase.
J Pharmacol Exp Ther June 1982 221:577-583
- Abstract
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- T D Lindstrom,
- P J Murphy,
- J K Smallwood,
- S A Wiest,
- and M I Steinberg
Correlation between the disposition of [14C]clofilium and its cardiac electrophysiological effect.
J Pharmacol Exp Ther June 1982 221:584-589
- Abstract
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- A Küpfer,
- P V Desmond,
- S Schenker,
- and R A Branch
Stereoselective metabolism and disposition of the enantiomers of mephenytoin during chronic oral administration of the racemic drug in man.
J Pharmacol Exp Ther June 1982 221:590-597
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- G F Anderson and
- B H Marks
Spare cholinergic receptors in the urinary bladder.
J Pharmacol Exp Ther June 1982 221:598-603
- Abstract
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- V H Denenberg,
- L P Zeidner,
- E B Thoman,
- P Kramer,
- J C Rowe,
- A F Philipps,
- and J R Raye
Effects of theophylline on behavioral state development in the newborn rabbit.
J Pharmacol Exp Ther June 1982 221:604-608
- Abstract
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- J E Pérez,
- L Borda,
- R Schuchleib,
- and P D Henry
Inotropic and chronotropic effects of vasodilators.
J Pharmacol Exp Ther June 1982 221:609-613
- Abstract
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- H M Sakr and
- E W Dunham
Mechanism of arachidonic acid-induced vasoconstriction in the intact rat kidney: possible involvement of thromboxane A2.
J Pharmacol Exp Ther June 1982 221:614-622
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- D A Koechel and
- G O Rankin
Acute effects of alkylating agents on canine renal function: N-ethylmaleimide and some of its potential biotransformation products.
J Pharmacol Exp Ther June 1982 221:623-628
- Abstract
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- B V Sastry,
- L K Owens,
- and V E Janson
Enhancement of the responsiveness of the rat diaphragm by L-methionine and phospholipid methylation and their relationships to aging.
J Pharmacol Exp Ther June 1982 221:629-636
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- M E Risner
Intravenous self-administration of phencyclidine and related compounds in the dog.
J Pharmacol Exp Ther June 1982 221:637-644
- Abstract
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- P J Marshall,
- J F Dixon,
- and L E Hokin
Prostaglandin E2 derived from phosphatidylinositol breakdown in the exocrine pancreas facilitates secretion by an action on the ducts.
J Pharmacol Exp Ther June 1982 221:645-649
- Abstract
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- P G Conway and
- N J Uretsky
Role of striatal dopaminergic receptors in amphetamine-induced behavioral facilitation.
J Pharmacol Exp Ther June 1982 221:650-655
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- W B Van de Graaff,
- W L Thompson,
- I Sunshine,
- D Fretthold,
- F Leickly,
- and H Dayton
Adsorbent and cathartic inhibition of enteral drug absorption.
J Pharmacol Exp Ther June 1982 221:656-663
- Abstract
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- Z C Wu,
- S D Kisslinger,
- and T S Gaginella
Functional evidence for the presence of cholinergic nerve endings in the colonic mucosa of the rat.
J Pharmacol Exp Ther June 1982 221:664-669
- Abstract
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- D L Niehoff,
- R D Mashal,
- W D Horst,
- R A O'Brien,
- J M Palacios,
- and M J Kuhar
Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.
J Pharmacol Exp Ther June 1982 221:670-675
- Abstract
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- R F Butz,
- R M Welch,
- and J W Findlay
Relationship between bupropion disposition and dopamine uptake inhibition in rats and mice.
J Pharmacol Exp Ther June 1982 221:676-685
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- T A Slotkin,
- G Barnes,
- C Lau,
- F J Seidler,
- P Trepanier,
- S J Weigel,
- and W L Whitmore
Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover.
J Pharmacol Exp Ther June 1982 221:686-693
- Abstract
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- E F El-Fakahany,
- A T Eldefrawi,
- and M E Eldefrawi
Nicotinic acetylcholine receptor desensitization studied by [3H]perhydrohistrionicotoxin binding.
J Pharmacol Exp Ther June 1982 221:694-700
- Abstract
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- N Ackerman,
- S Martinez,
- T Thieme,
- and A Mirkovich
Relationship between adherence, chemotaxis and the accumulation of rat polymorphonuclear leukocytes at an inflammatory site.
J Pharmacol Exp Ther June 1982 221:701-707
- Abstract
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- R C James,
- D R Goodman,
- and R D Harbison
Hepatic glutathione and hepatotoxicity: changes induced by selected narcotics.
J Pharmacol Exp Ther June 1982 221:708-714
- Abstract
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- L C Stoner and
- M E Trimble
Effects of MK-196 and furosemide on rat medullary thick ascending limbs of Henle in vitro.
J Pharmacol Exp Ther June 1982 221:715-720
- Abstract
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- R L Rodgers and
- J H McNeill
Effect of reserpine pretreatment on guinea pig ventricular performance and responsiveness to inotropic agents.
J Pharmacol Exp Ther June 1982 221:721-730
- Abstract
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- K R Krijgsheld,
- H J Koster,
- E Scholtens,
- and G J Mulder
Cholestatic effect of harmol glucuronide in the rat. Prevention of harmol-induced cholestasis by increased formation of harmol sulfate.
J Pharmacol Exp Ther June 1982 221:731-734
- Abstract
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- G T Shearman and
- A Herz
Evidence that the discriminative stimulus properties of fentanyl and ethylketocyclazocine are mediated by an interaction with different opiate receptors.
J Pharmacol Exp Ther June 1982 221:735-739
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- A Berdeaux,
- P Duhazé,
- and J F Giudicelli
Pharmacological analysis of beta adrenoceptor blockade-induced coronary blood flow redistribution in dogs using l-penbutolol.
J Pharmacol Exp Ther June 1982 221:740-747
- Abstract
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- Y Ohizumi,
- Y Ishida,
- and S Shibata
Mode of the ciguatoxin-induced supersensitivity in the guinea-pig vas deferens.
J Pharmacol Exp Ther June 1982 221:748-752
- Abstract
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- N B Shepperson,
- N Duval,
- R Massingham,
- and S Z Langer
Differential blocking effects of several dopamine receptor antagonists for peripheral pre- and postsynaptic dopamine receptors in the anesthetized dog.
J Pharmacol Exp Ther June 1982 221:753-761
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- B Wilffert,
- P B Timmermans,
- and P A van Zwieten
Extrasynaptic location of alpha-2 and noninnervated beta-2 adrenoceptors in the vascular system of the pithed normotensive rat.
J Pharmacol Exp Ther June 1982 221:762-768
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- M Corbic,
- M Dumont,
- G De Couët,
- and S Erlinger
Choleretic and diuretic properties of dihydroxydibutyl ether in the rat.
J Pharmacol Exp Ther June 1982 221:769-774
- Abstract
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- M Endoh,
- S Yamashita,
- and N Taira
Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle.
J Pharmacol Exp Ther June 1982 221:775-783
- Abstract
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- H Y Chang,
- R M Klein,
- and G Kunos
Selective desensitization of cardiac beta adrenoceptors by prolonged in vivo infusion of catecholamines in rats.
J Pharmacol Exp Ther June 1982 221:784-789
- Abstract
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- W Legrum and
- J Frahseck
Acceleration of 7-[methoxy-14C]coumarin-derived carbon dioxide exhalation by cobalt pretreatment in mice.
J Pharmacol Exp Ther June 1982 221:790-794
- Abstract
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- T Satoh,
- T Igarashi,
- T Hirota,
- and H Kitagawa
Induction of hepatic gamma-glutamyl transpeptidase in rats by repeated administration of aminopyrine.
J Pharmacol Exp Ther June 1982 221:795-800
- Abstract
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- K M Schwartz,
- F Urthaler,
- and T N James
The direct negative chronotropic action of prazosin on the canine sinus node.
J Pharmacol Exp Ther June 1982 221:801-805
- Abstract
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- K Munakata,
- J A Dominic,
- and B Surawicz
Variable effects of isoproterenol on action potential duration in guinea-pig papillary muscle: differences between nonsteady and steady state; role of extracellular calcium concentration.
J Pharmacol Exp Ther June 1982 221:806-814
- Abstract
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- J E Bourdeau,
- S L Buss,
- and G G Vurek
Inhibition of calcium absorption in the cortical thick ascending limb of Henle's loop by furosemide.
J Pharmacol Exp Ther June 1982 221:815-819
- Abstract
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- A R Wakade,
- T D Wakade,
- C Müller,
- and M Schwab
Epinephrine as a tool to investigate the question of recycling of sympathetic storage vesicles in the heart: chemical and morphological studies.
J Pharmacol Exp Ther June 1982 221:820-827
- Abstract
- Full Text (PDF)

Effects of inducers and inhibitors of cytochrome P-450-linked monooxygenases on the toxicity, in vitro metabolism and in vivo irreversible binding of 2-methylnaphthalene in mice.

Vascular tolerance to nitroglycerin and cyclic GMP generation in rat aortic smooth muscle.

Independent mechanisms for bradykinin-mediated prostaglandin E2 and cyclic GMP syntheses in rabbit renal inner medulla slices.

Monensin inhibits catecholamine synthesis in pheochromocytoma cells.

Noradrenergic modulation of serotonin synthesis and metabolism. I. Inhibition by clonidine in vivo.

Comparison of the effects of trimethadione and its primary metabolite dimethadione on neuromuscular function and the effects of altered pH on the actions of dimethadione.

Antiarrhythmic activity of the O-demethyl metabolite of encainide.

Hepatorenal failure induced by tetracycline in dogs with portacaval shunt.

Effects of chronic treatment with thyroxine and estradiol on estrogen concentration in serum and on hepatic microsomal catechol estrogen formation in female rats.

Ketamine and ditran block end-plate ion conductance and [3H]phencyclidine binding to electric organ membrane.

Effects of chemical sympathectomy on the increases in plasma catecholamines and dopamine-beta-hydroxylase induced by forced immobilization and insulin-induced hypoglycemia: origin and fate of plasma dopamine-beta-hydroxylase.

Correlation between the disposition of [14C]clofilium and its cardiac electrophysiological effect.

Stereoselective metabolism and disposition of the enantiomers of mephenytoin during chronic oral administration of the racemic drug in man.

Spare cholinergic receptors in the urinary bladder.

Effects of theophylline on behavioral state development in the newborn rabbit.

Inotropic and chronotropic effects of vasodilators.

Mechanism of arachidonic acid-induced vasoconstriction in the intact rat kidney: possible involvement of thromboxane A2.

Acute effects of alkylating agents on canine renal function: N-ethylmaleimide and some of its potential biotransformation products.

Enhancement of the responsiveness of the rat diaphragm by L-methionine and phospholipid methylation and their relationships to aging.

Intravenous self-administration of phencyclidine and related compounds in the dog.

Prostaglandin E2 derived from phosphatidylinositol breakdown in the exocrine pancreas facilitates secretion by an action on the ducts.

Role of striatal dopaminergic receptors in amphetamine-induced behavioral facilitation.

Adsorbent and cathartic inhibition of enteral drug absorption.

Functional evidence for the presence of cholinergic nerve endings in the colonic mucosa of the rat.

Binding of a radiolabeled triazolopyridazine to a subtype of benzodiazepine receptor in the rat cerebellum.

Relationship between bupropion disposition and dopamine uptake inhibition in rats and mice.

Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover.

Nicotinic acetylcholine receptor desensitization studied by [3H]perhydrohistrionicotoxin binding.

Relationship between adherence, chemotaxis and the accumulation of rat polymorphonuclear leukocytes at an inflammatory site.

Hepatic glutathione and hepatotoxicity: changes induced by selected narcotics.

Effects of MK-196 and furosemide on rat medullary thick ascending limbs of Henle in vitro.

Effect of reserpine pretreatment on guinea pig ventricular performance and responsiveness to inotropic agents.

Cholestatic effect of harmol glucuronide in the rat. Prevention of harmol-induced cholestasis by increased formation of harmol sulfate.

Evidence that the discriminative stimulus properties of fentanyl and ethylketocyclazocine are mediated by an interaction with different opiate receptors.

Pharmacological analysis of beta adrenoceptor blockade-induced coronary blood flow redistribution in dogs using l-penbutolol.

Mode of the ciguatoxin-induced supersensitivity in the guinea-pig vas deferens.

Differential blocking effects of several dopamine receptor antagonists for peripheral pre- and postsynaptic dopamine receptors in the anesthetized dog.

Extrasynaptic location of alpha-2 and noninnervated beta-2 adrenoceptors in the vascular system of the pithed normotensive rat.

Choleretic and diuretic properties of dihydroxydibutyl ether in the rat.

Positive inotropic effect of amrinone in relation to cyclic nucleotide metabolism in the canine ventricular muscle.

Selective desensitization of cardiac beta adrenoceptors by prolonged in vivo infusion of catecholamines in rats.

Acceleration of 7-[methoxy-14C]coumarin-derived carbon dioxide exhalation by cobalt pretreatment in mice.

Induction of hepatic gamma-glutamyl transpeptidase in rats by repeated administration of aminopyrine.

The direct negative chronotropic action of prazosin on the canine sinus node.

Variable effects of isoproterenol on action potential duration in guinea-pig papillary muscle: differences between nonsteady and steady state; role of extracellular calcium concentration.

Inhibition of calcium absorption in the cortical thick ascending limb of Henle's loop by furosemide.

Epinephrine as a tool to investigate the question of recycling of sympathetic storage vesicles in the heart: chemical and morphological studies.

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