Abstract
The calculation of the index λ in parallel line biological assays yields comparative information about the precision of the method. Further calculations and logarithmic transformations are needed to describe the minimum standard error of potency estimates derived in the assay with a given number of subjects, or alternatively to estimate the minimum number of assay subjects to achieve a desired minimum error.
The table presented in this paper obviates the need for such calculations. If shows directly the relationship between λ, the number of assay subjects and the minimum standard error expressed as a per cent of a potency estimate. Examples are given of the use of the table.
Footnotes
- Received April 30, 1958.
JPET articles become freely available 12 months after publication, and remain freely available for 5 years.Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page.
|
Log in using your username and password
Purchase access
You may purchase access to this article. This will require you to create an account if you don't already have one.