Data Supplement

Files in this Data Supplement:

• Data Supplement - Supplemental Figure 1. Data for each μ10 M dose of β-PEA tyramine, tryptamine, octopamine, dopamine,norepinephrine, serotonin and (+) methamphetamine are shown in Figure 7, and the full dose response curves for these compounds as well as (+)amphetamine, (-)amphetamine,(+)MDMA, (-)MDMA modafinil, GABA and Salvinorin A are shown in Supplemental Fig. S1.
• Data Supplement - Supplemental Figure 2. In DAT-TAAR1, NET-TAAR1 or SERT-TAAR1 cells indatraline, or methylphenidate, desipramine and citalopram (each at 10 μM) respectively, largely reduced enhancement of TAAR1 activation by β-PEA, tyramine, tryptamine, octopamine, dopamine or (+)methamphetamine. Data for each 10 μM dose is shown in Fig. 8, and the full dose response curves for these compounds are shown in Supplemental Fig. S2.
• Data Supplement - Supplemental Figure 3. Whereas DAT enhanced the TAAR1 response to dopamine, DAT had no effect on D1 response to dopamine. Data for each 10 μM dose is shown in Fig. 9A-B, and the full dose response curves are shown in Supplemental Fig.S3.