The Role of Prostaglandin E Receptor-Dependent Signaling via cAMP in Mdr1b Gene Activation in Primary Rat Hepatocyte Cultures
J Pharmacol Exp Ther Ziemann et al.
317: 378
Data Supplement
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FIG. 1. Enhancement of intracellular cAMP levels in misoprostol-treated rat hepatocytes.
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FIG. 2. Concomitant incubation of hepatocytes with AH23848B and Rho123 during the Rho123 accumulation assay did not significantly interfere with attainment of steady-state Rho123 levels.
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FIG. 3. EP4 mRNA expression in primary rat hepatocyte cultures. One-step RT-PCR analysis.
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FIG. 4. Complete prevention of IBMX-induced mdr1b mRNA expression by the PKA inhibitor H89.