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Journal of Pharmacology And Experimental Therapeutics, Vol. 95, Issue 3, 318-321, 1949
Copyright © 1949 by American Society for Pharmacology and Experimental Therapeutics

EFFECTS OF MORPHINE, CODEINE, AND DILAUDID ON BLOOD FLOW

R. A. HUGGINS 1, C. A. HANDLEY 1, and M. LA FORGE 1

1 Department of Pharmacology, Baylor University College of Medicine

1. Elevation of the hind legs or head of a dog to 45° after the administration of morphine causes a significant reduction in blood flow to the part raised.

2. Morphine may produce a partial inhibition of the vasoconstrictor center.

3. Codeine and dilaudid lack this effect.

Submitted on November 8, 1948






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Copyright © 1949 by the American Society for Pharmacology and Experimental Therapeutics.